Sulforaphane
In people, broccoli-sprout sulforaphane raised the glutathione-bound clearance of an airborne toxin by 61%; in mice given binge alcohol, it kept fat out of the liver and restored its glutathione.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
In a double-blind trial of 144 healthy older adults, twelve weeks of sulforaphane quickened processing speed and eased negative mood against placebo.
Lowered ALT, the liver-damage enzyme, in a registered 24-week trial of 70 people, corroborated on gamma-GT.
The broccoli isothiocyanate — Nrf2 activation with human data on blood pressure and glycemic control, the master antioxidant switch.
Sulforaphane raises survival a quarter in human cells held a day under the 2.45 gigahertz field of microwaves and wi-fi, restoring 56% of the charge a cell needs to make energy.
Broccoli sprouts release it when chewed. Sulforaphane turns down NF-kB, dimming the inflammatory signal that lingers in hard-worked tissue.
The strongest Nrf2 activator here, proven three times over in cadmium models, and Nrf2 is what drives the body to build its own metal-binding protein.
Lowers serum ALT. 35 against 35 over 24 weeks, registered before enrollment, and corroborated separately on ALT and gamma-GTP.
The reference for benefit from mild stress: it frees the antioxidant switch directly, and small amounts drive the defense.
From broccoli sprouts, sulforaphane switches on the lung's detox genes — the airway widens for easier breathing and flinches less at each trigger.
It binds the sensor protein directly, mice bred without Nrf2 lose the benefit, and more than 20 human trials have tracked the switch responding in people.
The haze that clouds vision months after cataract surgery is lens cells creeping back across the membrane they were cleared from.
Broccoli sprout sulforaphane flips on antioxidant defense and glutathione conjugation, quiets inflammation, powers neurons and sharpens insulin's hearing.
Sulforaphane is what broccoli makes when you chew it, and it kept human fibroblasts dividing longer by firing up their built-in antioxidant response and easing oxidative damage.
In a randomized trial of nearly 300 people, broccoli-sprout sulforaphane switched on the body's own defense enzymes, speeding the clearance of airborne pollutants.
Where it appears
18 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- Anti-Adipogenic (Preadipocyte Arrest)
- Autonomous (Executive Command)
- Autophagy Activator (Cellular Self-Renewal)
- Ceramide Blocker (Lipotoxicity Neutralizer)
- EKG Cardioprotective (Contractile Reserve)
- Event Horizon (Post-Ethanol Restoration)
- Force Field (Genomic Radioprotection)
- Gainz (Muscle, Strength & Recovery)
- Heavy Metal Detox (Toxic Burden Excretion)
- Helico (Gastric Colonization Defense)
- Holy Grail (Fat Leaves As Breath)
- Hormesis (Adaptive Stress Conditioning)
- Lung Power (Respiratory Capacity)
- NRF2 Activator (Endogenous Antioxidant Induction)
- Ocular (Retinal & Macular Support)
- Rewire (Total Brain Reset)
- Senolytic (Senescent Zombie Cell Clearance)
- Victorious (Antiviral Immunity)