Grape seed
Vitis vinifera
Grape-seed proanthocyanidins stalled three lines of abnormal human pancreatic cells at the G2/M gate and tipped them into death, and mice eating them in ordinary feed grew smaller growths with the same fingerprint.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
Grape seed extract moved two numbers at once in pooled human trials: systolic pressure down 1.54 mmHg and resting heart rate down 1.42 bpm.
Oligomeric proanthocyanidins — human randomized trials show blood-pressure and endothelial-function gains, concentrated vascular polyphenols.
Vine seed extract offers oligomeric proanthocyanidins, which spare nitric oxide from oxidative loss so the gas can keep vessels supple and opening freely.
Grape-seed proanthocyanidins are powerful antioxidants; across controlled trials they lowered LDL cholesterol and blood pressure and improved fatty-liver markers — protecting the cardiometabolic system EDCs strain.
In animals, grape-seed proanthocyanidins raise the liver's NAD+ and its SIRT1 in step with the amount given.
Wine grapes lend their seeds and skins: the polyphenols open the vessels and ease the force against their walls, bringing blood where it's needed.
The gut lining kept its villi, the testis its sperm count and testosterone, and in human cells the double-strand DNA breaks fell.
The extract read here is from the leaf: it protected nerve cells against glutamate toxicity and lowered oxidative damage in roundworms through the DAF-16 / FOXO route.
Where it appears
15 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- ACB (Cell-Cycle Checkpoint Restraint)
- Ascendance (Analgesic & Anti-Inflammatory)
- Autonomous (Executive Command)
- EKG Cardioprotective (Contractile Reserve)
- Force Field (Genomic Radioprotection)
- Hormesis (Adaptive Stress Conditioning)
- NAD+ Booster (Cellular Energy Currency)
- Niagra (Desire, Arousal & Climax)
- NRF2 Activator (Endogenous Antioxidant Induction)
- Obesogen Blocker (Endocrine Disruptor Defense)
- Peel (Flavonoid Powerhouse)
- Plush (Collagen, Firmness & Glow)
- Pulsar (Vascular Pressure Regulation)
- SIRT1 Activator (Caloric-Restriction Mimetic)
- Super Tonic Hair (Follicular Restoration)