Luteolin
In stomach growths taken from patients and grown in mice, luteolin cut cMet, MMP9 and the division marker Ki-67.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
Luteolin switched on AMPK signaling in the fat under the skin of mice.
In animals given this dietary flavone, the electron microscope found cells packed with fresh disposal vesicles, the self-clearing program switched on, and luteolin reaches it by two routes at once.
In two independent laboratories, luteolin taken by mouth raised the NRF2 defense and lowered the NF-kB inflammation switch.
In the follicle, luteolin guards against the oxidative harm that ages hair, and protects the melanocyte stem cells that restock pigment with each new cycle.
Take the antioxidant switch out of a mouse and luteolin stops protecting.
Found in celery and parsley, luteolin raises antioxidant defense, mutes inflammatory NF-kB, and shields kidney cells against untimely self-destruction.
Two independent laboratories, both oral: Nrf2 raised with HO-1 and NQO1 behind it, and NF-κB lowered.
Luteolin, from celery and thyme, blunts an NAD+-eating enzyme that multiplies with age — so the cell's store of that coenzyme holds.
In mice with a cut knee ligament it slowed the joint's decay.
A flavone in celery, thyme and artichoke, luteolin intercepts the signal that turns inflammation on inside the cell before it reaches the surrounding tissue.
In head-to-head panels on senescent human cells, luteolin showed senotherapeutic activity alongside quercetin, fisetin and kaempferol.
Luteolin raises SIRT1 in a run of animal studies, several of which closed the loop by abolishing the effect with a chemical that shuts the enzyme down.
A flavone found in celery and artichoke, luteolin calms inflammation around the follicle and lowers a prostaglandin, the lipid that brakes hair growth.
Celery and parsley share this flavone, which damps inflammatory messengers and hands the cell the instruction to raise its protective enzymes.
Where it appears
15 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- ACB (Cell-Cycle Checkpoint Restraint)
- Adipocyte Apoptosis (Mature Fat Cell Clearance)
- Autophagy Activator (Cellular Self-Renewal)
- Ceramide Blocker (Lipotoxicity Neutralizer)
- Endurance Eternal (Pigment Preservation)
- Hormesis (Adaptive Stress Conditioning)
- Jing Force (Kidney Restoration)
- Liver Regenerator (Hepatic Restoration)
- NAD+ Booster (Cellular Energy Currency)
- NRF2 Activator (Endogenous Antioxidant Induction)
- Peel (Flavonoid Powerhouse)
- Senolytic (Senescent Zombie Cell Clearance)
- SIRT1 Activator (Caloric-Restriction Mimetic)
- Super Tonic Hair (Follicular Restoration)
- Victorious (Antiviral Immunity)