Saffron
Crocus sativus
The stigma of Crocus sativus, saffron raises serotonin tone and the vessel lining's nitric oxide — mood steadies and holds its ground under strain.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
In a 22-week randomized, double-blind trial of 54 older adults with memory decline, saffron matched a prescription comparator on the standard scales of memory and thinking.
In seventy-four teenagers with obesity, saffron brought weight, BMI and waist down over twelve weeks while placebo stood still.
Saffron's crocin and safranal lift mood by sustaining serotonin, and they shield neurons from the glutamate overdrive that frays the nervous system.
Crocin and safranal — human randomized trials show glycemic, lipid and endothelial benefit; the world's most precious spice, earning its place on evidence.
Safranal and crocin lift serotonin and mood, calm cortisol, sharpen memory and deepen sleep.
Crocin and safranal brighten mood, sharpen focus and help vessel linings make nitric oxide.
Crocus-stigma crocin — human randomized trials show meaningful mood elevation and cognitive support; the world's most precious spice, earning its place on evidence.
Pooled randomized trials carry its effect on low mood, measured on scored depression scales.
In 100 adults over fifty with early macular degeneration, crossed over against placebo, acuity and the retina's response improved.
Matched a prescription antidepressant over six weeks in mild to moderate depression, with fewer side effects; beat placebo across trials.
Crocus sativus improved validated depression rating scales in randomized placebo-controlled trials pooled by meta-analysis.
In laboratory cells, saffron's coloring acid turned stem-like cells back toward mature nerve cells.
Where it appears
13 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- ACB (Cell-Cycle Checkpoint Restraint)
- ALZ (Memory Preservation)
- Appetite Suppressant (Hunger Signal Control)
- Ecstatic (Nervous System Stand-Down)
- EKG Cardioprotective (Contractile Reserve)
- Event Horizon (Post-Ethanol Restoration)
- Hypnotic Sleep (Slow-Wave Architecture)
- Spice (Anti-Inflammatory Polyphenol Powerhouse)
- Male Fertility (Seminal Quality)
- Niagra (Desire, Arousal & Climax)
- Ocular (Retinal & Macular Support)
- Rewire (Total Brain Reset)
- Thunder (Erectile Performance)