Apigenin
Apigenin starts the recycling crew by the fasting route, and the clean-up is real: the p62 cargo that piles up when recycling stalls comes down, and stressed mice recover recycling in the hippocampus.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
Apigenin shuts off the master inflammation switch senescent cells use to broadcast damage, quieting aged kidneys and cells grown old in culture.
Chamomile's signature flavone binds the brain's benzodiazepine site, easing the reflex of alarm and lending a calm that leaves the mind awake.
Chamomile's quiet flavone, apigenin preserves NAD+, the coenzyme mitochondria need to burn fuel, by slowing the enzyme that drains it away.
In an accelerated-aging mouse model, the decline slowed.
In mice with autoimmune myocarditis, apigenin by mouth shifted immunity from the attacking gear to the calming one and eased heart inflammation and dysfunction.
Restrains CD38, the enzyme that devours NAD+ with age, leaving more repair currency for every cell.
Aged rat kidneys and human cells grown old in culture both quiet down under apigenin: it shuts off the master inflammation switch that senescent cells use to broadcast damage to their neighbors.
Parsley and chamomile's flavone: in lab studies it lowered TGF-β1, a signal that ends a hair's growth phase, and lengthened follicles grown in culture.
Chamomile's calming flavone has a second trade: it protects the mitochondria and helps them keep the steady output the cell spends its day on.
Where it appears
10 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- Autophagy Activator (Cellular Self-Renewal)
- Ceramide Blocker (Lipotoxicity Neutralizer)
- Ecstatic (Nervous System Stand-Down)
- Gainz (Muscle, Strength & Recovery)
- Hormesis (Adaptive Stress Conditioning)
- Myocarditis Antidote (Cardiac Inflammation Resolution)
- NAD+ Booster (Cellular Energy Currency)
- Senolytic (Senescent Zombie Cell Clearance)
- Super Tonic Hair (Follicular Restoration)
- Victorious (Antiviral Immunity)