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Botanical

Apocynum venetum

Apocynum venetum
Interstellar grade A

Human trial evidence: Randomized human trials, or a meta-analysis of them, measuring this pathway's own endpoint — either a clinical outcome or a validated biomarker.

Appears on 3 blend pages, each linked below.

Luobuma, the dogbane leaf brewed as tea across northern China — it lowers the cortisol that keeps the mind awake, and sleep arrives deeper and longer.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Eases the cortisol load of a strained day and settles the brain into deeper, longer sleep.

Ecstatic (Nervous System Stand-Down) →

Luobuma, the leaf northwest China brews as tea, eases the load on the stress response (HPA axis). In a randomized, double-blind, placebo-controlled trial of 476 adults seeking relief from stress, perceived stress and sleep disturbance improved significantly faster than on placebo over six weeks, and those on the leaf were significantly more likely to reach a clinically meaningful drop in stress.

Rewire (Total Brain Reset) →

Where it appears

3 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

Pathways it touches

HPA Axis / Cortisol Sleep
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