Urolithin A
Gut bacteria make it from pomegranate ellagitannins. Urolithin A clears out worn mitochondria and prompts fresh ones to replace them — mitophagy renewed.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
In randomized human trials urolithin A improved muscle strength and mitochondrial health; in animals with diabetic heart disease it raised SIRT1.
Urolithin A restored PINK1- and Parkin-dependent mitophagy in the kidneys of fructose-fed mice.
Urolithin A, made when the gut transforms pomegranate ellagitannins, renews worn mitochondria so muscle burns fat as its steady, primary fuel.
Pomegranate and walnut give gut bacteria the raw material for urolithin A, which clears worn-out mitochondria and makes room for fresh ones.
In a randomized, placebo-controlled trial in middle-aged adults, improved muscle strength and mitochondrial health by recycling damaged mitochondria.
Pomegranate's gift, remade by gut bacteria: it tells tired mitochondria to recycle themselves, and the cell rebuilds its power plants fresh and whole.
Where it appears
8 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- Anti-Fatigue (Cellular Energy Endurance)
- Autophagy Activator (Cellular Self-Renewal)
- Gainz (Muscle, Strength & Recovery)
- Holy Grail (Fat Leaves As Breath)
- NAD+ Booster (Cellular Energy Currency)
- Senolytic (Senescent Zombie Cell Clearance)
- SIRT1 Activator (Caloric-Restriction Mimetic)
- Victorious (Antiviral Immunity)