Hesperidin
In roundworms this citrus compound lengthens lifespan, raises oxidative-stress resistance and blunts amyloid toxicity by driving autophagy, the cell's clear-out of damaged parts.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
The citrus flavanone hesperidin lowered all five markers of new fat-cell formation in subcutaneous fat.
In mice on a high-fat diet, hesperidin, the main flavonoid of oranges, lowered liver fat and blood fats.
Citrus-peel hesperidin prompts cells to make more of their own antioxidant enzymes through Nrf2.
Orange-peel hesperidin tones veins and fine vessels, raises nitric oxide, trims blood fats, broadens insulin's reach and damps NF-kB's inflammatory call.
Part of a quercetin, rutin, luteolin and hesperidin combination studied in people for markers of immune aging.
Where it appears
8 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- Anti-Adipogenic (Preadipocyte Arrest)
- Ceramide Blocker (Lipotoxicity Neutralizer)
- Event Horizon (Post-Ethanol Restoration)
- Hormesis (Adaptive Stress Conditioning)
- Jing Force (Kidney Restoration)
- Peel (Flavonoid Powerhouse)
- Senolytic (Senescent Zombie Cell Clearance)
- Super Tonic Hair (Follicular Restoration)