Sugar burning
Glucose metabolism
Also searched as Glucose metabolism.
You want it apt: brisk fuel when demanded, not a chronic proliferative idle.
In depth
Glycolysis — rapid glucose burning for quick energy; the same shift, unchecked, fuels proliferative disease (the Warburg effect).
What drives it
Hypoxia response increases it.
Semenza 1994, J Biol Chem 269:23757 — HIF-1 directly transactivates glycolytic enzyme genes (aldolase A, PGK1, PKM) via hypoxia-response elements. PMID 8089148
Growth driver increases it.
Osthus & Dang 2000, J Biol Chem — c-Myc directly transactivates glycolytic genes (GLUT1, PFK, enolase, LDHA), driving glucose uptake and the Warburg shift. PMID 10823814
What it drives
It increases Reducing power supply.
Glucose-6-phosphate is the branch point into the pentose phosphate pathway. Carried by the intermediary-metabolism and clinical reviews. doi 10.1016/j.molmet.2023.101755 · PMC9967593
It increases Central fuel molecule.
Pyruvate is decarboxylated to acetyl-CoA. Carried by the intermediary-metabolism and clinical reviews. doi 10.1016/j.molmet.2023.101755 · PMC9967593
It increases Lactate handling.
The terminal step when pyruvate exceeds oxidative capacity. Carried by the intermediary-metabolism, micronutrient and clinical reviews. doi 10.3390/nu18132141 · PMC9967593
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.