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Ingredient

Crocin (saffron)

Crocus sativus

Crocin (saffron) (Crocus sativus)
Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 4 blend pages, each linked below.

In laboratory cells, saffron's coloring acid turned stem-like cells back toward mature nerve cells.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

In a mouse model of immune-driven heart inflammation, crocin, saffron's main component, lowered NLRP3 and cleaved gasdermin D, the proteins behind rupturing heart-cell death, and eased the inflammation.

Myocarditis Antidote (Cardiac Inflammation Resolution) →

Crocetin, the carotenoid crocin becomes in the body, raises NRF2 and heme oxygenase-1 in an arthritis model.

NRF2 Activator (Endogenous Antioxidant Induction) →

Saffron's crocin lifted the signal for two energy-sensing enzymes in people with coronary artery disease.

SIRT1 Activator (Caloric-Restriction Mimetic) →

Where it appears

4 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

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