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Fungus

Shiitake (Lentinula edodes)

lentinula edodes

Shiitake (Lentinula edodes)
Interstellar grade B+

Human trial evidence: Randomized human trials, or a meta-analysis of them, measuring this pathway's own endpoint — either a clinical outcome or a validated biomarker.

Appears on 5 blend pages, each linked below.

Lentinan, purified from shiitake, has been an approved medicine in Japan since 1985, and mouse work traces the immune route it takes.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Five trials, 650 patients with advanced stomach disease: adding its beta-glucan to standard treatment cut the risk of dying about a fifth.

ACB (Cell-Cycle Checkpoint Restraint) →

Shiitake's beta-glucan kept mice on a fattening diet from losing cognitive ground, working upward from the colon: gut flora shift, inflammation falls, brain growth factor and synapses hold.

Trinity (Mind Body Spirit Harmonizer) →

The forest mushroom of Japanese kitchens: lentinan, its signature glucan, trains the immune system's sentries to recognize and meet a threat.

Victorious (Antiviral Immunity) →

Works on the interferon alarm: the body's earliest antiviral signal, raised in the hours before the wider immune system arrives.

Victorious (Antiviral Immunity) →

The shiitake cap lowers the fats traveling in the blood - a mushroom prized in Japanese kitchens for the same property that earns its place here.

Anti-Fatigue (Cellular Energy Endurance) →

Where it appears

5 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

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