Amycenone (Hericium/Lion's mane)
Hericium erinaceus
Lion's mane gives amycenone, which stirs nerve growth factor and BDNF — plasticity for the brain to build new links and sharpen recall.
What the evidence shows
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In colon cells resistant to 5-fluorouracil, erinacine S raised programmed death from 7% to 59%.
In a randomized trial in mild cognitive impairment, cognition improved against placebo; further randomized trials tested cognition and mood in young adults, over one day and over 28 days.
Yamabushitake, the monk's-beard mushroom, carries hericenones that raise brain growth factors, spur new neurons and rewiring, and shelter them from attrition.
Where it appears
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