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Ingredient

Nobiletin (citrus peel flavone)

Nobiletin (citrus peel flavone)
Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 2 blend pages, each linked below.

Nobiletin, the citrus-peel flavone, lowered PPAR-gamma, aP2, C/EBP-alpha, FASN and SREBP-1c in both subcutaneous and inguinal fat of high-fat-fed mice.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Nobiletin, a flavone concentrated in the peel of mandarins and other citrus, resets the cell's daily clock and with it the tissue's timely answer to insulin.

Peel (Flavonoid Powerhouse) →

Where it appears

2 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

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