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Ingredient

Hesperetin

Hesperetin
Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 3 blend pages, each linked below.

Hesperetin, the aglycone freed from orange-peel hesperidin, prompts the artery lining to release nitric oxide, and the vessel eases open under the pulse.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Hesperetin raises SIRT1, a cell-maintenance enzyme, in animal models of treatment-related heart damage.

SIRT1 Activator (Caloric-Restriction Mimetic) →

Where it appears

3 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

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