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Pathway

Supports young eyes

The Eye That Grows Too Long

1 blend on this site modulates it.

You want this restrained. Glasses correct the focus; they do not shorten the eye — and a longer eye carries lifelong risk of retinal disease.

In depth

Myopia — short-sightedness driven by excessive axial elongation of the eyeball. Uncorrected refractive error is the single largest cause of vision impairment worldwide.

What drives it

Fasting insulin increases it.

Chronic hyperinsulinemia can result in the suppression of insulin-like growth factor binding protein-3 (IGFBP-3) and the induction of insulin-like growth factor-1 (IGF-1) in scleral fibroblasts, leading to…. 10.1016/j.mehy.2016.01.009. doi 10.1016/j.mehy.2016.01.009

Growth factor increases it.

the promotion of increased insulin-like growth factor-1 (IGF-1) and decreased insulin-like growth factor binding protein-3 (IGFBP-3) action in scleral fibroblasts could contribute to the axial elongation of…. 10.1016/j.mehy.2016.01.009. doi 10.1016/j.mehy.2016.01.009

Blood-sugar support increases it.

High-glycemic diets rich in refined carbohydrates can induce hyperinsulinemia and elevate insulin-like growth factor 1 (IGF-1) levels, which may stimulate excessive axial elongation of the eye. 10.1016/j.mehy.2016.01.009. doi 10.1016/j.mehy.2016.01.009

What it drives

It reduces Vision.

Uncorrected refractive error remains a leading cause of vision impairment in all countries among both children and adult populations. 10.1016/S2214-109X(17)30393-5. doi 10.1016/S2214-109X(17

It increases Supports the optic nerve.

Key risk factors for glaucoma include elevated IOP, genetic predisposition, high myopia, and certain systemic conditions such as hypertension and cardiovascular disease. PMC11289249

Blends that modulate it

Each blend page names this pathway and carries the study behind its claim.

Ocular (Retinal & Macular Support) →

See it on the map

Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.

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