Supports the aging macula
You want this restrained. There is no cure; the evidence is about slowing progression, not reversing it.
In depth
Age-related macular degeneration — loss of cells in the macula, the part of the retina that carries straight-ahead vision.
What drives it
Builds macular pigment reduces it.
The hazard ratio (HR) for progression to late AMD comparing lutein/zeaxanthin with no lutein/zeaxanthin was 0.91 (95% CI, 0.84-0.99; P = .02) ... When the lutein/zeaxanthin main effects analysis was…. PMID 35653117
Oxidative stress increases it.
Like beta-carotene, lutein and zeaxanthin are antioxidants with activity in the retina. PMID 35653117 Verbatim: “Multiple studies investigating AMD with the use of animal models and cell culture have identified oxidative stress-related retinal damage as an important contributing factor”. doi 10.3945/an.116.013177 · PMID 35653117
Insulin sensitivity reduces it.
Accumulated evidence has demonstrated a strong relationship between IR and a higher incidence of several dramatically vision-threatening retinal diseases, including diabetic retinopathy, age-related macular…. 10.3389/fendo.2024.1415521. doi 10.3389/fendo.2024.1415521
What it drives
It reduces Vision.
Macular degeneration causes cells in the macula to die, eventually leading to vision loss. PMID 35653117
It reduces Visual perception.
The macula is the part of the retina that provides clear and straight-ahead vision. PMID 35653117
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.