Peroxide-clearing enzyme
Catalase
Also searched as Catalase.
Concentrated in peroxisomes, where hydrogen peroxide is produced deliberately. Requires heme, so iron status reaches antioxidant defense as well as oxygen carriage.
In depth
Decomposes hydrogen peroxide to water and oxygen at extraordinary speed.
What drives it
Superoxide dismutase increases it.
The product of one is the substrate of the other. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
Antioxidant defense increases it.
10.3390/antiox11050978 — NRF2 induces catalase. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/antiox11050978 · PMC9967593
Heme iron increases it.
Catalase is a hemoprotein - iron status reaches antioxidant defense as well as oxygen carriage. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
Peroxisomes increases it.
Catalase is concentrated where hydrogen peroxide is made deliberately. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
What it drives
It reduces Oxidative stress.
Decomposes hydrogen peroxide to water. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.