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Ingredient

St. John's wort

Hypericum perforatum

St. John's wort (Hypericum perforatum)
Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 2 blend pages, each linked below.

Cochrane: superior to placebo in major depression. Interacts with SSRIs, contraceptives and many medicines.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

St John's Wort's hyperforin-type compounds switched on antioxidant and heme-clearing defenses in zebrafish and protected nerve tissue there.

Hormesis (Adaptive Stress Conditioning) →

Where it appears

2 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

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