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Ingredient

Piperine (black pepper)

Piper nigrum

Piperine (black pepper) (Piper nigrum)
Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 3 blend pages, each linked below.

In the dish, black pepper extract killed every adult blood fluke within six to twelve hours, and it also worked in infected hamsters.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Piperine, the pungent principle of black pepper, lowered FAS, SREBP-1c, C/EBP-alpha and FABP4 in visceral fat against the high-fat diet.

Anti-Adipogenic (Preadipocyte Arrest) →

The black-pepper alkaloid switches off the two growth signals that stop a cell recycling its own worn-out parts.

Autophagy Activator (Cellular Self-Renewal) →

Black pepper's piperine blocks the enzyme that returns released fat straight back into storage, the loop that reclaims most of what a resting fat cell lets go.

Lipolytic (Stored-Fat Mobilization) →

Where it appears

3 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

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