Membrane lipids
Synthesis begins in the peroxisome, so peroxisomal function limits it. The vinyl-ether bond is preferentially oxidized, which has been read as a sacrificial antioxidant role — plausible and not established as an outcome.
In depth
Ether phospholipids that act as sacrificial antioxidants in the membrane itself — they are consumed protecting the lipids around them. Depleted early in neurodegeneration.
What drives it
Peroxisomes increases it.
Plasmalogen synthesis begins in the peroxisome, so peroxisomal function limits it. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
What it drives
It increases Memory & focus.
Weaker evidence - heavily represented in brain membranes and reduced in neurodegenerative disease; causality not established. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
It reduces Oxidative stress.
The vinyl-ether bond is preferentially oxidized - read as a sacrificial antioxidant role, plausible and not established as an outcome. Carried by the intermediary-metabolism, micronutrient and redox reviews. doi 10.3390/nu18132141 · PMC9967593
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.