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Pathway

Learning Without Knowing

In depth

A subdomain of learning and memory: skills and habits acquired without conscious recollection. Classically preserved in amnesia when declarative memory is destroyed.

What drives it

Motivation increases it.

Levodopa medication enhanced incidental learning by patients with PD on a probabilistic sequence learning paradigm even though the patients were not aware of the existence of the sequence or their acquired knowledge. The results suggest a role in acquiring incidental motor sequence learning for dorsal striatal areas strongly affected by dopamine depletion in early PD. Verbatim from the source for this edge — PMC5155668, PMC4118028. doi 10.1016/j.brainres.2006.12.051 · PMC5155668

What it drives

It increases Learning & memory.

The DSM-5 Neurocognitive Work Group agreed on six principal domains of cognitive function, each with subdomains. Learning and memory comprises immediate memory, recent memory (free recall, cued recall and recognition memory), and very-long-term memory including semantic, autobiographical and implicit learning. Taxonomic edge, not a causal mechanism: this is a DSM-5 domain/subdomain relationship, not a pathway acting on another. Sachdev 2014, Nat Rev Neurol 10:634-642 — Classifying neurocognitive disorders: the DSM-5 approach. doi 10.1038/nrneurol.2014.181 The manual's own table, which carries the immediate/recent nesting this line states, is reproduced verbatim as 'Immediate memory, recent memory' in Table 1 of doi 10.1186/s13643-019-1220-4 (Domains used to diagnose major and mild neurocognitive disorders in the DSM-5). Scope stated before anyone asks: Sachdev's Figure 2 is an ABRIDGED rendering of the DSM-5 table and does not carry every subdomain named here, so the manual's own wording is cited beside it. doi 10.1038/nrneurol.2014.181

See it on the map

Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.

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