Ketone production
Hepatic ketogenesis from fatty acids
Also searched as Hepatic ketogenesis from fatty acids.
Fatty acids released into the blood have exactly two honest destinations: burned in muscle, or turned into ketones by the liver. Everything else is recapture — back into the fat cell, or rebuilt from glycerol. That is why releasing fat without opening an exit moves it around rather than removing it, and why a release agent should be paired with something that burns.
In depth
Released fatty acids converted to ketones — one of only two ways fat genuinely leaves the body.
What drives it
Releases stored fat increases it.
10.1186/s13054-019-2506-6 — The other disposal route, and the one that actually removes fat from the body. 'Die aus der enzymatischen Spaltung entstandenen Fettsäuren werden in das Blut abgegeben. Sie können von der Muskulatur zur beta-oxidation oder von der Leber zur KETOGENESE aufgenommen und verstoffwechselt werden' = the fatty acids from lipolysis enter the blood and can be taken up by muscle for beta-oxidation or by the liver for ketogenesis (DocCheck Flexikon — Lipolyze (deutsch)). ⇒ released fat has exactly two honest exits — burned in muscle, OR converted to ketones in the liver. Everything else is recapture. A release agent with neither exit open is moving fat around, not removing it. doi 10.1186/s13054-019-2506-6
What it drives
It increases Ketone fuel.
10.3390/vetsci7030095 — Nbk560564 — the other disposal route, and the one that actually removes fat from the body. 'Die aus der enzymatischen Spaltung entstandenen Fettsäuren werden in das Blut abgegeben. Sie können von der Muskulatur zur beta-oxidation oder von der Leber zur KETOGENESE aufgenommen und verstoffwechselt werden' = the fatty acids from lipolysis enter the blood and can be taken up by muscle for beta-oxidation or by the liver for ketogenesis (DocCheck Flexikon — Lipolyze (deutsch)). ⇒ released fat has exactly two honest exits — burned in muscle, OR converted to ketones in the liver. Everything else is recapture. A release agent with neither exit open is moving fat around, not removing it. doi 10.3390/vetsci7030095
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.