Immune defense under radiation
You want it low: this is the immune system being suppressed, so less of it means more of the defense you already have.
In depth
Immunosuppression — the immune system held below its own baseline by an outside force rather than by disease. Radiation is the case this pathway was built for: it does not make the immune system fight harder, it stops it fighting at all.
What drives it
Radiation exposure increases it.
Verbatim: “机体免疫系统是辐射损伤的敏感系统, 其中T淋巴细胞敏感性最高。机体由于辐射损伤产生免疫功能紊乱状态, 表现为免疫活性细胞数量减少.” (中国辐射卫生 ZGFSWS 2008-1-121; PMID 24161486) [Also stated on the pathology node: the same source, stated on the pathology node. The quote reports a reduction in immunocompetent cell numbers under radiation injury — that is an increase in immunosuppression. No new evidence is claimed; the radiation → immune link (a brake) and the radiation → immunosuppression link (a driver) are the same finding on two nodes of opposite class.]. PMID 24161486
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.