Phloretin

Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 1 blend page, linked below.

The apple compound binds KEAP1, the sensor that holds NRF2 captive, and pries the pair apart.

Where it appears

One blend page carries this ingredient. Open it and you will find this ingredient in the list.

• NRF2 Activator (Endogenous Antioxidant Induction)