Androgen precursor
Androstenedione
Also searched as Androstenedione.
It sits at a junction. Where it goes next shapes the hormonal balance downstream, which is why it matters in fertility and cycle disorders.
In depth
An adrenal and ovarian androgen precursor that can be converted onward to either testosterone or estrogen.
What it drives
It increases Estrogen balance.
Using labelled steroid infusions in healthy men and women, the authors measured peripheral conversion of circulating androstenedione into estrone and estradiol, quantifying androstenedione as a direct precursor of blood estrogen. doi 10.1172/JCI106185 · PMID 5355335
Blends that modulate it
Each blend page names this pathway and carries the study behind its claim.
See it on the map
Open the causal map to follow this pathway upstream and downstream, arrow by arrow, each with its study.