What is behind Circulation & Cold Extremities
Core temperature maintenance across metabolic rate, circulation and the hypothalamic set-point.
Evidence on these pathways
Body temperature control. “Prolonged exposure to glucocorticoid suppresses the function of human BAT” — doi.org/10.3390/biom11111573
Body temperature control. “As in other large mammals, skeletal muscles are the primary source of heat production recruited in cold-exposed humans” — doi.org/10.3389/fphys.2017.00889
Body temperature control. “Aging is associated with an attenuated physiological ability to dissipate heat” — doi.org/10.1155/2018/8306154
Formulas that act on these pathways
What this page does not claim
This page names the pathways involved and the published evidence on each. It does not claim that any formula treats, cures or prevents Circulation & Cold Extremities. Every study above is linked by its own identifier so it can be opened and checked.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.