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Withaferin A (Ashwaganda)
Withaferin A (Ashwaganda)
2, 3-Dihydro-3ฮฒ-methoxy Withaferin-A Protects Normal Cells against Stress: Molecular Evidence of Its Potent Cytoprotective Activity
2, 3-Dihydrowithaferin A-3ฮฒ-O-sulfate, a new potential prodrug ofย withaferin Aย from aeroponically grown Withania somnifera
3beta-methoxy derivation ofย Withaferin-aย Attenuates its Anticancer potency: Bioinformatics and molecular evidences
5,6-De-epoxy-5-en-7-one-17-
hydroxyย withaferin A, a new cytotoxic steroid from Withania somnifera L. Dunal leaves
A novel combination ofย withaferin Aย and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers
A novel combination ofย withaferin Aย and sulforaphane inhibits epigenetic machinery, cellular viability and induces apoptosis of breast cancer cells
A rapid and simple high performance thin layer chromatographic method for simultaneous analysis of ฮฒ-sitosterol-D-glucoside, gallic acid,ย withaferin Aย and withanolide A in Ashvagandharishta
A Study on the efficacy ofย Withaferin-Aย in reducing oxidative stress against DEN induced hepatocellular carcinoma
A validated and densitometric HPTLC method for the quantification of Withaferin-A and Withanolide-A in different plant parts of two morphotypes of Withania somnifera
A110 THORACIC CANCERS: PATHOGENESIS AND NOVEL TARGETS: The Use Of Withaferin-A As An Anti-Metastatic Agent In Non-Small Cell Lung Cancer
Abstract A10: Withaferin-A, a natural compound inhibits AKT-induced metastatic colorectal cancer
Abstract A115:ย withaferin Aย downregulates her-2/neu protein expression in human breast cancer cells.
Abstract A2-32: Identification ofย withaferin Aย as a novel cancer stem cell inhibitor to overcome drug resistance in non-small cell lung carcinoma
Abstract A29: Targeting adenylate kinase-4 modulation of HIF-1ฮฑ: Stability identifies Withaferin-A suppresses lung cancer metastasis
Abstract A4:ย withaferin Aย induces apoptosis in imatinib-resistant CML cells by repressing the Akt signaling pathway
Abstract A48: Ovarian tumor-induced immunosuppression of NK cells and its prevention by dietary supplementation of herbalย withaferin Aย (Ashwagandha).
Abstract B41:ย withaferin Aย promotes ROS-mediated differentiation of neuroblastoma
Abstract B57: A natural plant-derived compound,ย withaferin A, exploits the stress pathway to induce antitumor immunity.
Abstract B84: WithaferinโA is a novel HSFโ1 inhibitor with potent antitumor effects in melanoma in vivo
Abstract C218: Novel therapeutic potential in targeting micro tubules by naturally occurring anti cancer agentย withaferin Aย in human cancers.
Abstract LB-113: A novel role ofย withaferin Aย as an effective pro-apoptotic receptor agonist (PARA) and insights into the underlying molecular mechanisms
Abstract LB-154: Epigenetic silencing of triple-negative breast cancer hallmarks byย withaferin A
Abstract NTOC-100: OVARIAN TUMOR-ASSOCIATED GRP78 INDUCES IMMUNOSUPPRESSION ANDย withaferin Aย (ASHWAGANDHA) ENHANCES ANTI โฆ
Abstract P2-09-12:ย withaferin A-mediated inhibition of breast carcinoma involves concomitant activation of CHOP and Elk1 via ERK/ribosomal S6 kinase (RSK) โฆ
Abstract# 3903: Inhibition of human cervical cancer cell growth byย withaferin Aย and potential mechanisms
Actin microfilament aggregation induced byย withaferin Aย is mediated by annexin II
Activation of signal transducer and activator of transcription 3 fails to confer resistance againstย withaferin A-induced apoptosis in human breast cancer cells
Age related differences in stress-induced neurobehavioral patterns in rats modulated by withaferin-A and other antioxidants
Agrobacterium rhizogenes mediated hairy root culture system of Withania somnifera L Dunal forย withaferin Aย production
Ameliorative effect ofย withaferin Aย on ageing-mediated impairment in the dopamine system and its associated behavior of Wistar Albino Rat
An adaptogen:ย withaferin Aย ameliorates in vitro and in vivo pulmonary fibrosis by modulating the interplay of fibrotic, matricelluar proteins, and cytokines
An analog ofย withaferin Aย activates the MAPK and glutathione โstressโ pathways and inhibits pancreatic cancer cell proliferation
Anti-cancer activity ofย withaferin Aย in B-cell lymphoma
Anti-cancer Effects and Molecular Mechanisms ofย withaferin A
Anticancer Effects ofย withaferin Aย in Head and Neck Squamous Cell Carcinomas through Modulation of Heat Shock Protein Expression
Anticancer effects ofย withaferin Aย on UP-LN1 carcinoma cells through the inhibition of STAT3 phosphorylation and IFN-ฮณ-mediated induction of metastatic cancer stem โฆ
Anti-cancer Mechanisms of the Natural Plant Derived Compound,ย withaferin Aย in HER-2/neu Breast Cancer
Anti-inflammatory effect ofย withaferin Aย on dopaminergic neuron of aged rat.
Anti-inflammatory effects ofย withaferin Aย in islet transplantation and pancreatitis.
Antiplatelet, anticoagulant, and profibrinolytic activities ofย withaferin A
Antiproliferation potential ofย withaferin Aย on human osteosarcoma cells via the inhibition of G2/M checkpoint proteins
Antitumor and radiosensitizing effects ofย withaferin Aย on mouse Ehrlich ascites carcinoma in vivo
Apoptosis induction by ayurvedic medicine constituentย withaferin Aย in human breast cancer cells is mediated by reactive oxygen species-dependent activation of Bak
Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitorย withaferin Aย and is facilitated by apoptotic topoisomerase IโDNA complex
AshwaMAX andย withaferin Aย inhibits gliomas in cellular and murine orthotopic models
Assessment of hepatoprotective and nephroprotective potential ofย withaferin Aย on bromobenzene-induced injury in Swiss albino mice: possible involvement of โฆ
Assessment of the Immune Status in โwithaferin Aโ Treated Rats in Experimental Mammary Carcinogenesis by Flow Cytometry
Astaxanthin andย withaferin Aย block paracrine cytokine interactions between UVB-exposed human keratinocytes and human melanocytes via the attenuation of โฆ
Autophagy fails to alterย withaferin A-mediated lethality in human breast cancer cells
Axl is a novel target ofย withaferin Aย in the induction of apoptosis and the suppression of invasion
Ayurvedic medicine constituentย withaferin Aย causes G2 and M phase cell cycle arrest in human breast cancer cells
Barrier protective effects ofย withaferin Aย in HMGB1-induced inflammatory responses in both cellular and animal models
Biomass production andย withaferin Aย synthesis by Withania somnifera grown in aeroponics and hydroponics
Biosynthesis of Withanolides in Acnistus breviflorus Chemical Degradation of 14C-Labelled Jaborosalactone A andย withaferin A
Biotransformation of withaferin-a by a culture ofArthrobacter simplex
Broad-spectrum antitumor properties ofย withaferin A: a proteomic perspective
Carbohydrate and elicitor enhanced withanolide (withaferin Aย and withanolide A) accumulation in hairy root cultures of Withania somnifera (L.)
Characterizingย withaferin Aย as a novel NRF2 inducer: implications for liver disease prevention
CHEMICAL PROFILING FOR FEW PLANT METABOLITES (WITHANOLIDE-A AND WITHAFERIN-A) INCLUDING ANTI-CANCER COMPOUNDS IN FOREST SPECIES โฆ
Chemistry ofย withaferin-A: chemo, regio, and stereoselective synthesis of novel spiro-pyrrolizidino-oxindole adducts of withaferin-A via one-pot three-component [3+ 2] โฆ
Chemo prevention effect ofย withaferin A, a natural compound, on mouse models of colorectal carcinogenesis
Chemopreventive and chemotherapeutic effect of Withaferin-A on in vivo models of prostate cancer
Chemotherapeutic effect ofย withaferin Aย in human oral cancer cells
CHEMOTHERAPEUTIC EFFICACY OF WITHAFERIN-A IN EXPERIMENTAL HEPATOCELLULAR CARCINOMA
Circadian time-dependent chemopreventive potential ofย withaferin-Aย in 7, 12-dimethyl-benz [a] anthracene-induced oral carcinogenesis
Combination ofย withaferin Aย and X-ray irradiation enhances apoptosis in U937 cells
Combination strategies for management of ovarian cancer using doxorubicin andย withaferin A
Combinatorialย withaferin Aย and Sulforaphane and Their Potential Roles in Breast Cancer Prevention and Therapy
Comparison of the Protective Effect of Withaferin-โAโand Hydrocortisone against CCL~ 4 induced Hepatotoxicity in Rats
Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase inย withaferin A-mediated inhibition of โฆ
Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy ofย withaferin Aย in Hepatocellular Carcinoma
Constituents of Withania somnifera Dun. III. The Side Chain ofย withaferin A*,1
Constituents of Withania somnifera Dun. Part IV. The structure ofย withaferin A
Constituents of Withania somnifera Dun. Part VI. The stereochemistry ofย withaferin A
Constituents of Withania somnifera Dun. Part VII. Rearrangements inย withaferin A
Constituents of Withania somnifera Dun. Part VIII. A new steroidal lactone, 27-deoxy-14-hydroxy-withaferin A
Correction:ย withaferin Aย Inhibits the Proteasome Activity in Mesothelioma In Vitro and In Vivo
Cytotoxicity of Ashwagandha Derivedย withaferin Aย to Human Cancer Cells: Molecular Insights into the Response of Telomerase Plus and Minus Cell
Cytotoxicity of Phytocompounds Cannabigerol (CBG) andย withaferin Aย to SKOV3 Ovarian Cancer Cells
Cytotoxicity ofย withaferin Aย in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling โฆ
Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated withย withaferin Aย (WA)
DD-03THE NATURALLY OCCURRING STEROID,ย withaferin A, IN SYNERGISTIC CONCERT WITH HER2/EGFR INHIBITORS ABROGATES PROLIFERATION OF โฆ
DDEL-04 AshwaMAX andย withaferin Aย inhibits gliomas in cellular and murine orthotopic models
Ddis-15. Synergistic Inhibition Of Glioma Cell Proliferation Byย withaferin Aย And Tumor Treating Fields
Determination ofย withaferin Aย and withanolide A in mice plasma using high-performance liquid chromatography-tandem mass spectrometry: application to โฆ
DETERMINATION OFย withaferin Aย CONTENT OF ROOT, STEM AND LEAF EXTRACTS OF WITHANIA SOMNIFERA (L) DUNAL COLLECTED IN KENYA
Determination ofย Withaferin-Aย in two Withania Species by RP-HPLC method
Development and optimization of hairy root culture systems in Withania somnifera (L.) Dunal forย withaferin-Aproduction
Development of a goat model for evaluation ofย withaferin A: Cervical implants for the treatment of cervical intraepithelial neoplasia
Development of a new method for identification and estimation of Withania somnifera root, and a method for quantitative analysis ofย withaferin Aย in young and old โฆ
Development of HPTLC fingerprint by simultaneous estimation of Ashwagandha (withaferin-A) and Glycyrrhiza (18-ฮฒ-glycyrrhetinic acid) in some polyherbal over the โฆ
DEVELOPMENT OF VALIDATED RP-HPLC METHOD FOR THE ESTIMATION OFย WITHAFERIN-Aย IN WITHANIA SOMNIFERA, Its EXTRACT AND POLYHERBAL โฆ
Development ofย withaferin Aย analogs as probes of angiogenesis
Different effects of 4ฮฒ-hydroxywithanolide E andย withaferin A, two withanolides from Solanaceae plants, on the Akt signaling pathway in human breast cancer cells
Differential activities of the two closely related withanolides,ย withaferin Aย and Withanone: bioinformatics and experimental evidences
Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells byย withaferin Aย and Siamois polyphenols
Differential effect ofย withaferin Aย treatment on activation of Notch1 and Notch2 in human breast cancer cells.
Disease subtype independent biomarkers of breast cancer prevention byย withaferin A
Disease SubtypeโIndependent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemicalย withaferin A
Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated withย withaferin A-induced apoptosis in MCF-7 โฆ
DOXIL when combined withย withaferin Aย (WFA) targets ALDH1 positive cancer stem cells in ovarian cancer
Drug carrier for sustained release ofย withaferin Aย for pancreatic cancer treatment
Dual Elicitation for Improved Production ofย withaferin Aย by Cell Suspension Cultures of Withania somnifera
Early-stage treatment withย withaferin Aย reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral โฆ
Effect of a radiosensitiser,ย withaferin A, on the free radical metabolising enzymes of neutrophils, in carcinoma of uterine cervix subjected to radiotherapy
Effect of rhizobacterial inoculation on withaferin-a content of ashwagandha (var. Jawahar 20) roots.
Effect ofย withaferin Aย on A549 cellular proliferation and apoptosis in non-small cell lung cancer
Effect ofย withaferin Aย on cells in tissue culture
Effect ofย withaferin Aย on Ehrlich ascites tumor cells. II. Target tumor cell destruction in vivo by immune activation
Effect ofย withaferin Aย on Ehrlich ascites tumor cellsโcytological observations
Effect ofย withaferin Aย on the development and decay of thermotolerance in B16F1 melanoma: A preliminary study
Effect of withaferin, a radiosensitizer, on the erythrocyte antioxid-ants in carcinoma of uterine cervix
Effects of dietary compounds sulforaphane andย withaferin Aย on MCF-7 breast cancer cells
Effects ofย withaferin Aย on Mouse Models of Alexander Disease
Efficacy of Withania somnifera chemotypes NMITLI โ 101R, 118R andย withaferin Aย against experimental visceral leishmaniasis
Elicitation of withaferin-A in hairy root culture of Withania somnifera (L.) Dunal using natural polysaccharides
Elucidating Anticancer Activity ofย withaferin A, Major Constituent of Withania somnifera Through Suppression of NF-ะบB, a Prominent Marker in Cancer
Elucidation of molecular mechanism of butyrate andย withaferin Aย induced antiangiogenesis and apoptosis
Endoplasmic reticulum stress mediatesย withaferin A-induced apoptosis in human renal carcinoma cells
Enhanced activity of chemotherapeutic drugs by blueberry anthocyanidins andย withaferin Aย against human lung cancer cells.
Enhanced bioproduction ofย withaferin Aย from suspension cultures of Withania somnifera.
Enhanced production ofย withaferin-Aย in shoot cultures of Withania somnifera (L) Dunal
Enhancement of radiation induced cell death in chicken B lymphocytes byย withaferin A
Enhancement of the response of B16F1 melanoma to fractionated radiotherapy and prolongation of survival byย withaferin Aย and/or hyperthermia
Epigenetic silencing of triple negative breast cancer hallmarks byย withaferin A
ERBB2 overexpression establishes ERBB3-dependent hypersensitivity of breast cancer cells toย withaferin A
ET-71 the antitumor effects ofย withaferin Aย in glioblastoma stem cells
Evaluation of analgesic, antipyretic and ulcerogenic effect ofย withaferin A
EVALUATION OF IN VITROย withaferin Aย PRODUCTION FROM WITHANIA COAGULANS (STOCKS) DUNAL
EVALUATION OFย withaferin Aย CONTENT IN DIFFERENT ACCESSIONS AND IN IN VITRO CULTURES OF WITHANIA COAGULANS (STOCKS) DUNAL
Evaluation ofย withaferin Aย content in different accessions and in in vitro cultures of Withania coagulans (Stocks) Dunal.
Evaluation of withaferin-A and analogues as antibacterial agents: Structure-activity relationship study
Examination of the effect of the natural plant extract,ย withaferin A, on heat shock protein gene expression in Xenopus laevis A6 cells
Examination of the effect ofย withaferin Aย on heat shock protein gene expression in Xenopus laevis A6 kidney epithelial cells
Expanding the Chemical Space ofย withaferin Aย by Incorporating Silicon to Improve its Clinical Potential on Human Ovarian Carcinoma Cells
Exploring the inhibitory activity of Withaferin-A against Pteridine reductase-1 of L. donovani
Extraction and Isolation ofย withaferin Aย (Steroidal Lactone) from Withania Somnifera Leafs and itโs TLC and HPLC Analysis.
Extraction Optimization for Phenolic- and Withanolide-Rich Fractions from Withania somnifera Roots: Identification and Quantification ofย withaferin A, 12-Deoxywithastromonolide, and Withanolide A in Plant Materials and Marketed Formulations Using a Reversed-Phase HPLCโPhotodiode Array Detection Method
FORMULATION AND EVALUATION OF SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM FOR SOLUBILITY AND BIOAVAILABILITY ENHANCEMENT OF POORLY WATER SOLUBLEย withaferin A
Genetic andย withaferin Aย Analysis of Iranian Natural Populations of Withania Somnifera and W. Coagulans by RAPD and HPTLC
Glucose metabolismโtargeted therapy andย withaferin Aย are effective for epidermal growth factor receptor tyrosine kinase inhibitorโinduced drugโtolerant persisters
Growth arrest by the antitumor steroidal lactoneย withaferin Aย in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of ฮฒ โฆ
Growth inhibitory effects ofย withaferin Aย on MDS-L cellsโA human 5q Myelodysplastic Syndrome (MDS) cell line
High performance thin layer chromatography method for simultaneous estimation of vicine, trigonelline andย withaferin Aย in a polyherbal antidiabetic formulation
Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme byย Withaferin-A
HPLC analysis ofย withaferin Aย in Withania somnifera (L.) Dunal
HPTLC method for analysis ofย withaferin-Aย in Ashwagandha (Withania somnifera)
Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drugย withaferin A
Hypothalamic ATP Has a Crucial Role in the Pathogenesis of Leptin Resistance: A Potential Mechanism for the Amelioration of Leptin Resistance by Celastrol andย withaferin A
Identification and quantitative analysis of cellular proteins affected by treatment withย withaferin Aย using a SILAC-based proteomics approach
Identification of Biological Targets of the Angiogenic Agentย withaferin A
Identification ofย withaferin Aย as a potential candidate for anti-cancer therapy in non-small cell lung cancer
Imagingย withaferin A-Vimentin Interactions in Live Cells and Fibrotic Tissues
Immunosuppressive activity of two plant steroidal lactonesย withaferin Aย and withanolide E.
Impeding the single-strand annealing pathway of DNA double-strand break repair byย withaferin A-mediated FANCA degradation
In Vitro and In Vivo Cytotoxic Effects ofย withaferin Aย on Retinal Epithelial Pigmented Cells
In vitro propagation andย withaferin Aย production in Withania ashwagandha, a rare medicinal plant of India
IN VITROย withaferin Aย PRODUCTION BY WITHANIA SOMNIFERA SUSPENSION CULTURE
In vivo growth inhibitory and radiosensitizing effects ofย withaferin Aย on mouse Ehrlich ascites carcinoma
Increase ofย withaferin And a glutathione contents of Withania somnifera (L.) Dun. shoots cultivated in vitro on medium supplemented with Zn*[2+
Increased production of withanolide A, withanone, andย withaferin Aย in hairy root cultures of Withania somnifera (L.) Dunal elicited with methyl jasmonate and salicylic โฆ
INCREASING BIOMASS ACCUMULATION ANDย withaferin Aย PRODUCTION IN CELL SUSPENSION CULTURE OF WITHANIA SOMNIFERA
Induction of apoptosis byย withaferin Aย in human leukemia U937 cells through down-regulation of Akt phosphorylation
Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolideย withaferin A
Inhibition of inflammatory cytokine-induced response in human islet cells byย withaferin A
Inhibition of monosodium urate crystal-induced inflammation byย withaferin A
Inhibition of NFฮบB by the natural productย withaferin Aย in cellular models of Cystic Fibrosis inflammation
Inhibition of the NEMO/IKKฮฒ association complex formation, a novel mechanism associated with the NF-ฮบB activation suppression by Withania somniferaโs key metaboliteย withaferin A
Inhibition of VEGF: a novel mechanism to control angiogenesis by Withania somniferaโs key metaboliteย withaferin A
Inhibitory effect ofย withaferin Aย on Helicobacter pyloriโinduced ILโ8 production and NFโฮบB activation in gastric epithelial cells
Insights from the predicted structural analysis of carborane substitutedย withaferin Aย with Indoleamine-2, 3-dioxygenase as a potent inhibitor
Integrated In silico Docking and MoMA Simulation Approaches Revealย withaferin A, Withalongolides A and B as Potent Aldo-Keto Reductase (AKR) 1C3 โฆ
Interaction studies of Withania somniferaโs key metaboliteย withaferin Aย with different receptors associated with cardiovascular disease
Investigation of the role ofย withaferin Aย derivative in modulating signaling pathways in transformed cancer cells for inhibition of invasion and metastasis
ISOLATION AND CHARACTERIZATION OF WITHAFERIN-A FROM THE WITHANIA SOMNIFERA (ASHWAGANDHA)
Isolation and identification ofย withaferin Aย (Steroidal Lactone) from Withania somnifera (Ashwagandha).
Isolation ofย Withaferin-Aย from Withania Somnifera plant root and its effects on cancer rats
Lack of the cytochrome P450 3A interaction of methanolic extract of Withania somnifera,ย withaferin A, Withanolide A and Withanoside IV
L-Arginine abolishes the anxiolytic-like effect ofย withaferin Aย in the elevated plus-maze test in rats
LC-MS/MS method for the quantification ofย withaferin-Ain plant extracts of Withania spp.
Leaf ontogenic phase-related dynamics ofย withaferin Aย and withanone biogenesis in ashwagandha (Withania somnifera Dunal.)- an important medicinal herb
Ligand based virtual screening to identify potential anti cancer ligands similar toย withaferin Aย targeting indoleamine 2, 3-dioxygenase
Lipopolysaccharides-stimulated macrophage products enhanceย withaferin A-induced apoptosis via activation of caspases and inhibition of NF-ฮบB pathway in human โฆ
Liquid chromatography-tandem mass spectrometry to assess the pharmacokinetics and tissue distribution ofย withaferin Aย in rats
Mammary cancer chemoprevention byย withaferin Aย is accompanied by in vivo suppression of self-renewal of cancer stem cells
Mechanistic elucidation of the antitumor properties ofย withaferin Aย in breast cancer
Metabolic alterations in mammary cancer prevention byย withaferin Aย in a clinically relevant mouse model
Metabolomics and proteomics reveal inhibition of glycolysis inย withaferin A-mediated prevention of mammary carcinogenesis in MMTV-neu mice.
Microbial transformations of natural antitumor agents. 23. conversion of withaferin-A to 12ฮฒ-and 15ฮฒ-hydroxy derivatives of withaferin-A.
Microbial transformations of natural antitumor agents. 7. 14-alpha-Hydroxylation of withaferin-A by Cunninghamella elegans (NRRL 1393)
Microbiological and chemical dehydrogenation ofย withaferin A
Mild ThioโDiversification of Bioactive Natural Products.ย withaferin A: A Case study.
Mitotic catastrophe and inhibition of growth of Castration Resistant Prostate Cancers by a dietary agent Withaferin-A.
Molecular conformations. Part VI. The structure ofย withaferin A: X-ray analysis ofย withaferin Aย acetate p-bromobenzoate
Molecular docking and dynamic simulation studies evidenced plausible immunotherapeutic anticancer property byย withaferin Aย targeting indoleamine 2, 3 โฆ
Molecular insight in the multifunctional activities ofย withaferin A
Molecular insights into cancer therapeutic effects of the dietary medicinal phytochemicalย withaferin A
Molecular Insights Into Withaferin-A-Induced Senescence: Bioinformatics and Experimental Evidence to the Role of NFฮบB and CARF
Molecular mechanisms of hyperthermia-induced apoptosis enhanced byย withaferin A
Molecular targets and mechanisms of cancer prevention and treatment byย withaferin A, a naturally occurring steroidal lactone
Myeloid-derived suppressor cell function is reduced byย withaferin A, a potent and abundant component of Withania somnifera root extract
Natural products triptolide, celastrol, andย withaferin Aย inhibit the chaperone activity of peroxiredoxin I
Natural withanolideย withaferin Aย induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation
Neuroprotective Effect of CR-777, a Glutathione Derivative ofย withaferin A, Obtained through the Bioconversion of Withania somnifera (L.) Dunal Extract by the Fungus โฆ
Neuroprotective efficacy ofย withaferin Aย on aging mediated oxidative stress in striatum and Substantia nigra of wistar albino rat.
Nf-ฮบb-Dependent Inhibition of HIV-1 Transcription byย withaferin A
Niosomalย withaferin Aย with better antitumor efficacy
Nitrogen treatment enhances sterols andย withaferin Aย through transcriptional activation of jasmonate pathway, WRKY transcription factors, and biosynthesis genes in โฆ
Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drugย withaferin A
Notch-1 inhibition byย Withaferin-A: a therapeutic target against colon carcinogenesis
Novel cytotoxic and antitumor agents. IV.ย withaferin A: relation of its structure to the in vitro cytotoxic effects on P388 cells.
Novel validated HPTLC method for estimation ofย withaferin Aย in polyherbal formulations
On the action and mechanism of withaferin-A from Withania somnifera, a novel and potent melanin dispersing agent in frog melanophores
Optimisation of a microwaveโassisted method for extractingย withaferin Aย from Withania somnifera Dunal. using central composite design
Optimization of Carbon Source for Hairy Root Growth andย withaferin Aย and Withanone Production in Withania somnifera
Oral administration ofย withaferin Aย inhibits carcinogenesis of prostate in TRAMP model
Oral administration of Withaferin-A effectively suppresses prostate carcinogenesis in PTEN-Knockout mice
Overexpression of microRNA-25 byย withaferin Aย induces cyclooxygenase-2 expression in rabbit articular chondrocytes
Oxidative cytotoxic agentย withaferin Aย resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway โฆ
Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A
Parโ4 dependent modulation of cellular ฮฒโcatenin by medicinal plant natural product derivative 3โazidoย withaferin A
Par-4-dependent apoptosis by the dietary compoundย withaferin Aย in prostate cancer cells
Pathological Evaluation of Anti-Tumour Effects ofย withaferin Aย against Experimentally Induced Mammary Tumour in Rats
PAWR-mediated suppression of BCL2 promotes switching of 3-azidoย withaferin Aย (3-AWA)-induced autophagy to apoptosis in prostate cancer cells
Peptidylโprolyl cis/trans isomerase Pin1 regulatesย withaferin Aโmediated cell cycle arrest in human breast cancer cells
Pharmacogenomic Analysis of Adenylate Kinase-4 Gene Expression Signature Identifies Withaferin-A as an Anti-Metastatic Agent in Non-Small Cell Lung Cancer
Pharmacological and analytical aspects ofย withaferin A: A concise report of current scientific literature
Pharmacological levels ofย withaferin Aย (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells
Pharmaological Control of Angiofibrosis byย withaferin A
Phytochemicals,ย withaferin Aย and carnosol, overcome pancreatic cancer stem cells as c-Met inhibitors
Pin1 is a novel target ofย withaferin A, a mammary cancer chemopreventative steroidal lactone from Withania somnifera
Piriformospora indica elicitation ofย withaferin Aย biosynthesis and biomass accumulation in cell suspension cultures of Withania somnifera
PO-293 Withaferin-A: a candidate anti-tumour natural compound for non-small cell lung cancer and stem cells
Possible nitric oxide modulation in protective effects ofย withaferin Aย against stress induced neurobehavioural changes
Potent Anti-Fibrotic Activity ofย withaferin Aย in Ocular Injury Models
Potential Angiopreventive Mode of Action ofย withaferin A
Preliminary Study on the Synthesis ofย withaferin A.
Prevention of articular cartilage degeneration in a rat model of monosodium iodoacetate induced osteoarthritis by oral treatment withย withaferin A
Prevention of mammary carcinogenesis and pulmonary metastasis by Ayurvedic medicine constituentย withaferin Aย in a clinically-relevant transgenic mouse model.
Preventive effects ofย withaferin Aย isolated from the leaves of an Indian medicinal plant Withania somnifera (L.): comparisons with 17-ฮฒ-estradiol and alendronate
Probing the anticancer mechanism of prospective herbal drugย withaferin Aย on mammals: a case study on human and bovine proteasomes
Production dynamics ofย withaferin Aย in Withania somnifera (L.) Dunal complex
Production of reactive oxygen species byย withaferin Aย causes loss of type collagen expression and COX-2 expression through the PI3K/Akt, p38, and JNK pathways in โฆ
Production of the Anticancer Compoundย withaferin Aย from Genetically Transformed Hairy Root Cultures of Withania Somnifera
Production ofย withaferin Aย in shoot cultures of Withania somnifera
Proinflammatory cytokines IL-6 and TNF-ฮฑ increased telomerase activity through NF-ฮบB/STAT1/STAT3 activation, andย withaferin Aย inhibited the signaling in colorectal โฆ
Protection against cerebral infarction byย withaferin Aย involves inhibition of neuronal apoptosis, activation of PI3K/Akt signaling pathway, and reduced intimal โฆ
Protective effect ofย Withaferin-Aย on micronucleus frequency and detoxication agents during experimental oral carcinogenesis
Protective effect ofย Withaferin-Aย on tumour formation in 7, 12-dimethylbenz [a] anthracene induced oral carcinogenesis in hamsters
Protective Effect Of Withania Somnifera And Its Active Componentย withaferin Aย In Bromobenzene Induced Hepato And Nephrotoxicity
Protective role of withaferinโA on 7, 12โdimethylbenz (a) anthraceneโinduced genotoxicity in bone marrow of Syrian golden hamsters
Protective role of Withaferin-A on immunoexpression of p53 and bcl-2 in 7, 12-dimethylbenz (a) anthracene-induced experimental oral carcinogenesis
Protective role of Withaferin-A on red blood cell integrity during 7, 12-dimethylbenz [a] anthracene induced oral carcinogenesis
Proteomic characterization ofย withaferin A-targeted protein networks for the treatment of monoclonal myeloma gammopathies
Quantification of withaferin-A and withanolide-A in diploid (nโ=โ12) and tetraploid cytotypes (nโ=โ24) of โRassbharyโ, Physalis angulata L
Radiosensitization of a mouse melanoma byย withaferin A: In vivo studies
Radiosensitizing effect ofย withaferin Aย combined with hyperthermia on mouse fibrosarcoma and melanoma
Rapid and sensitive method for determination of withaferin-A in human plasma by HPLC
Reactions ofย withaferin-Aย with model biological nucleophiles
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compoundย withaferin Aย with concomitant protection by N-acetyl cysteine
Regiospecific Synthesis of Ring A Fusedย withaferin Aย Isoxazoline Analogues: Induction of Premature Senescence by W-2b in Proliferating Cancer Cells
Relationship between chemical structure and antitumor activity ofย withaferin Aย analogues
Response of a mouse fibrosarcoma toย withaferin Aย and radiation
Response Surface Optimization Of In Vitro Culture Medium For Enhanced Production Of The Therapeutically Important Secondary Metaboliteโwithaferin A
Ring A structural modified derivatives ofย withaferin Aย and the evaluation of their cytotoxic potential
Role of mitogenโactivated protein kinases and Mclโ1 in apoptosis induction byย withaferin Aย in human breast cancer cells
Role ofย withaferin Aย as a Neuroprotectant against Beta Amyloid Induced Toxicity and associated mechanism
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OFย WITHAFERIN-Aย IN RANGER CAPSULE
Safety and Pharmacokinetics ofย Withaferin-Aย in advanced stage high grade Osteosarcoma: A phase I trial
Safety assessment of Withania somnifera extract standardized forย withaferin A: acute and sub-acute toxicity study
Scientific Evidence for Anticancer Effects of Withania somnifera and Its Primary Bioactive Componentย withaferin A
Selective cytotoxicity of non-small cell lung cancer cells by theย withaferin A-fortified root extract of Ashwagandha involves differential cell-cycle arrest and โฆ
Semi-synthesis of a novel hybrid isoxazolidino withaferin via chemoselective and diastereoselective 1, 3-dipolar nitrone cycloaddition reaction
Semi-synthetic approach ofย withaferin A: Related steroidal lactones as a potent anti proliferative agents
Simultaneous estimation of guggulsterone E, guggulsterone Z, KBA, AKBA,ย withaferin Aย and 6-gingerol by using HPLC-DAD method from ariflex tablet โฆ
Simultaneous Estimation of Stigmasterol andย withaferin Aย in Union Total Herbal Formulation Using Validated HPTLC Method
Simultaneous Estimation ofย withaferin Aย and Z-Guggulsterone in Marketed Formulation by RP-HPLC
Simultaneous High-Performance Thin-Layer Chromatographic Quantification ofย withaferin Aย and Withanolide A in Solanum nigrum L. โBlack Nightshadeโ
STAT3 inhibitory activity of structurally simplifiedย withaferin Aย analogues
Stress induced somatic embryogenesis: an alternative technique to enhance production ofย withaferin Aย in Indian ginseng (Withania somnifera L.) Dunal
Structure-based design of new analogs ofย withaferin Aย as antitumor agents
Structure-based design, synthesis, and biological evaluation ofย withaferin A-analogues as potent apoptotic inducers
Studies on oral bioavailability and firstโpass metabolism ofย withaferin Aย in rats using LCโMS/MS and QโTRAP
Study on the Anticarcinogenic Efficacy of Withaferin-A in DEN Induced Hepatocellular Carcinoma: Morphology and Histopathology
Synergistic antitumor activity ofย withaferin Aย combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human โฆ
Synergistic cytotoxic action of cisplatin andย withaferin Aย on ovarian cancer cell lines
Synergistic inhibition of glioma cell proliferation byย withaferin Aย and tumor treating fields
Synthetic studies of withanolide I Synthesis of AB ring moiety ofย withaferin A
Targeting glioblastoma stem cells withย withaferin A
Targeting Her-2/neu breast cancers with a plant derived natural compound,ย withaferin Aย (53.15)
Targeting NFฮบB and MAP Kinases in Pancreatic Beta Cells to Suppress Islet Inflammation Byย withaferin A.: Abstract# C1727
Targeting RAW 264.7 macrophages (M1 type) withย Withaferin-Aย decorated mannosylated liposomes induces repolarization via downregulation of NF-ฮบB and โฆ
The Anti-Angiogenic Activity ofย withaferin Aย Is Mediated by the Intermediate Filament Protein Vimentin
The chemopreventive effect ofย withaferin Aย on spontaneous and inflammation-associated colon carcinogenesis models
The effect ofย withaferin Aย on human peripheral blood lymphocytes: An electron-microscope study
The effect ofย withaferin Aย on plant cells
The effect ofย withaferin A, a natural steroidal lactone, on the fine structure of S-180 tumor cells
The Effects ofย withaferin Aย on Normal and Malignant Immune Cells
The glucose metabolism targeting therapies andย withaferin Aย eliminate epidermal growth factor tyrosine kinase inhibitor-induced drug-tolerant persisters in non-small โฆ
The inhibitory effect ofย withaferin Aย on the growth of orthotopic xenograft tumor of hepatocellular carcinoma in nude mice and the mechanism
The Natural Compoundย withaferin Aย Covalently Binds to Cys239 of ฮฒ-Tubulin to Promote Tubulin Degradation
The tumor inhibitor and antiangiogenic agentย withaferin Aย targets the intermediate filament protein vimentin
The tumor proteasome is a primary target for the natural anticancer compoundย withaferin Aย isolated from โIndian winter cherryโ
The use ofย withaferin Aย to study intermediate filaments
Therapeutic relevance ofย withaferin-Aย induced apoptotic and autophagic regulation in human cancer cell-lines
Thiol dependent NF-ฮบB suppression and inhibition of T-cell mediated adaptive immune responses by a naturally occurring steroidal lactoneย withaferin A
To check the glioprotective effect ofย withaferin Aย on C6 Glioma cell Culture challenged with Kainic Acid
To Test The Role Ofย withaferin Aย In Neuroprotection On Sh-Sy5Y Cell Line Challenged By Kainic Acid
Towards Therapeutic Chemical Genetics: Polypharmacology ofย withaferin Aย on Corneal Angiogenesis and Retinal Gliosis is Mediated by Type III Intermediate โฆ
Treatment of adult and pediatric high-grade gliomas withย withaferin A: antitumor mechanisms and future perspectives
Tumor inhibitors. XXXIX. Active principles of Acnistur arborescens. Isolation and structural and spectral studies ofย withaferin Aย and withacnistin
Tumor Size Reduction Withย withaferin Aย In A Murine Model Of Uveal Melanoma
Validated HPLC method development for simultaneous analysis ofย withaferin-Aย and 6-gingerol
Vassobia breviflora root-extractย withaferin Aย as a novel cytotoxic and synergistic agent against malignant gliomas
Vimentin and Glial Fibrillar Acidic Protein are Targeted byย withaferin Aย in Retinal Gliosis
Vimentin Phosphorylation Underlies Corneal Myofibroblast Sensitivity toย withaferin A
Vimentin phosphorylation underlies myofibroblast sensitivity toย withaferin Aย in vitro and during corneal fibrosis
Water-solubleย withaferin Aย polymer prodrugs via a drug-functionalized RAFT CTA approach
withaferin A
withaferin Aย (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells
withaferin Aย abolishes the stem cell factor-stimulated pigmentation of human epidermal equivalents by interrupting the auto-phosphorylation of c-KIT in human โฆ
withaferin Aย activates stress signalling proteins in high risk acute lymphoblastic leukemia
withaferin Aย activity against glioblastoma cells: Supression of microtubule dynamics
withaferin Aย alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells
withaferin Aย alters intermediate filament organization, cell shape and behavior
withaferin Aย ameliorates ovarian cancer-induced cachexia and proinflammatory signaling
withaferin Aย ameliorates renal injury due to its potent effect on inflammatory signaling
withaferin Aย analogs that target the AAA+ chaperone p97
withaferin Aย analogues up-regulate the MAPK and glutathione metabolic pathways prior to activation of apoptosis in pancreatic cancer cells
withaferin Aย and its potential role in glioblastoma (GBM)
withaferin Aย and sulforaphane regulate breast cancer cell cycle progression through epigenetic mechanisms
withaferin Aย and tumor treating fields synergistically inhibit glioma proliferation
withaferin Aย and Withanolide D analogues with dual heat-shock-inducing and cytotoxic activities: semisynthesis and biological evaluation
withaferin Aย associated differential regulation of inflammatory cytokines
withaferin Aย attenuates Alcohol Abstinence Signs in Rats
withaferin Aย attenuates bleomycinโinduced scleroderma by targeting FoxO3a and NFโฮบฮฒ signaling: Connecting fibrosis and inflammation
withaferin Aย attenuates lipopolysaccharide-induced acute lung injury in neonatal rats.
withaferin Aย Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondrial Death Cascade Blockade in an AMPK Dependent Manner
withaferin Aย attenuates ovalbumin induced airway inflammation
withaferin Aย binds covalently to the N-terminal domain of annexin A2
withaferin Aย blocks formation of IFN-ฮณ-induced metastatic cancer stem cells through inhibition of the CXCR4/CXCL12 pathway in the UP-LN1 carcinoma cell model
withaferin Aย causes activation of Notch2 and Notch4 in human breast cancer cells
withaferin Aย causes autophagy in normal as well as cancerous human breast cells
withaferin Aย causes FOXO3a-and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo
withaferin Aย disrupts ubiquitin-based NEMO reorganization induced by canonical NF-ฮบB signaling
withaferin Aย down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial โฆ
withaferin Aย downregulates tubulins and covalently binds ฮฒ-tubulin at cysteine-303 in human breast cancer cells
withaferin Aย effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis
withaferin Aย enhances radiation-induced apoptosis in Caki cells through induction of reactive oxygen species, Bcl-2 downregulation and Akt inhibition
withaferin Aย exerts anti-tumor effects in gliobIastoma cells by arresting cell cycle at G2/M phase
withaferin Aย from cell cultures of Withania somnifera
withaferin Aย Improves Nonalcoholic Steatohepatitis in Mice
withaferin Aย in combination with cisplatin targets CD44 and Oct4 positive cancer stem cells in ovarian cancer
withaferin Aย induced impaired autophagy and unfolded protein response in human breast cancer cell-lines MCF-7 and MDA-MB-231
withaferin Aย induces apoptosis and inhibits adipogenesis in 3T3โL1 adipocytes
withaferin Aย induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through โฆ
withaferin Aย induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells
withaferin Aย induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2
withaferin Aย induces apoptosis in rat C6 glioma cells through regulating NF-ฮB nuclear translocation and activation of caspase cascade
withaferin Aย induces apoptosis through the generation of thiol oxidation in human head and neck cancer cells
withaferin Aย induces cell death and differentiation in multiple myeloma cancer stem cells
withaferin Aย induces cell death selectively in androgen-independent prostate cancer cells but not in normal fibroblast cells
withaferin Aย induces cytoprotective autophagy in hepatocellular cancer cells and concomitant autophagic inhibition augments the efficacy ofย withaferin Aย in โฆ
withaferin Aย induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway
withaferin Aย induces mitochondrial-dependent apoptosis in non-small cell lung cancer cells via generation of reactive oxygen species.
withaferin Aย induces nonprotective autophagy in a STK11-independent manner and mediates breast cancer inhibition via energetic impairment
withaferin Aย induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms
withaferin Aย induces oxidative stress-mediated apoptosis and DNA damage in oral cancer cells
withaferin Aย Induces p27Kip1 Expression to Inhibit Corneal Angio-Fibrosis
withaferin Aย induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells
withaferin Aย induces proteasome inhibition, endoplasmic reticulum stress, the heat shock response and acquisition of thermotolerance
withaferin Aย induces proteasome-dependent degradation of breast cancer susceptibility gene 1 and heat shock factor 1 proteins in breast cancer cells
withaferin Aย induces ROS-mediated paraptosis in human breast cancer cell-lines MCF-7 and MDA-MB-231
withaferin Aย inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells
withaferin Aย inhibits adipogenesis in 3T3-F442A cell line, improves insulin sensitivity and promotes weight loss in high fat diet-induced obese mice
withaferin Aย inhibits apoptosis via activated Akt-mediated inhibition of oxidative stress
withaferin Aย inhibits breast cancer invasion and metastasis at subโcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
withaferin Aย inhibits epithelial to mesenchymal transition in non-small cell lung cancer cells
withaferin Aย inhibits epithelial-to-mesenchymal transition in non-small lung cell cancer cells via regulation of SMAD and NFkB signaling
withaferin Aย inhibits experimental epithelialโmesenchymal transition in MCFโ10A cells and suppresses vimentin protein level in vivo in breast tumors
withaferin Aย inhibits expression of ataxia telangiectasia and Rad3โrelated kinase and enhances sensitivity of human breast cancer cells to cisplatin
withaferin Aย inhibits helicobacter pylori-induced production of IL-1ฮฒ in dendritic cells by regulating NF-ฮบB and NLRP3 inflammasome activation
withaferin Aย inhibits hepatoma cell proliferation through induction of apoptosis and cell cycle arrest
withaferin Aย inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown
withaferin Aย inhibits inflammatory responses induced by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in macrophages
withaferin Aย inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-ฮบB in RAW 264.7 cells
withaferin Aย inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells
withaferin Aย inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells
withaferin Aย inhibits matrix metalloproteinase-9 activity by suppressing the Akt signaling pathway
withaferin Aย inhibits NF-kappaB activation by targeting cysteine 179 in IKKฮฒ
withaferin Aย inhibits nuclear factor-ฮบB-dependent pro-inflammatory and stress response pathways in the astrocytes
withaferin Aย inhibits osteosarcoma cells through inactivation of Notch-1 signalling
withaferin Aย inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation
withaferin Aย inhibits prostate carcinogenesis in a PTEN-deficient mouse model of prostate cancer
withaferin Aย inhibits STAT3 and induces tumor cell death in neuroblastoma and multiple myeloma
withaferin Aย inhibits the malignant pleural mesothelioma growth in vitro and in vivo
withaferin Aย inhibits the proliferation of gastric cancer cells by inducing G2/M cell cycle arrest and apoptosis
withaferin Aย inhibits the proteasome activity in mesothelioma in vitro and in vivo
withaferin Aย inhibits tumor necrosis factor-ฮฑ-induced expression of cell adhesion molecules by inactivation of Akt and NF-ฮบB in human pulmonary epithelial cells
withaferin Aย Is a Chemical Genetic Probe of the Intermediate Filament Protein Vimentin
withaferin Aย is a leptin sensitizer with strong antidiabetic properties in mice
withaferin Aย is a potent inhibitor of angiogenesis
withaferin Aย is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo
withaferin Aย is effective in inhibiting the survival of B cell lymphomas and chronic lymphocytic leukemias (P2052)
withaferin Aย modulates AIM2 inflammasome and caspase-1 expression in THP-1 polarized macrophages
withaferin Aย modulates the Spindle Assembly Checkpoint by degradation of Mad2โCdc20 complex in colorectal cancer cell lines
withaferin Aย Prevents Myocardial Ischemia/Reperfusion Injury by Upregulating AMP-Activated Protein Kinase-Dependent B-Cell Lymphoma2 Signaling
withaferin Aย Production by Root Cultures of Withania coagulans
withaferin Aย promotes proliferation and migration of brain endothelial cells
withaferin Aย Protects Against High-Fat DietโInduced Obesity Via Attenuation of Oxidative Stress, Inflammation, and Insulin Resistance
withaferin Aย protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation
withaferin Aย protects against spinal cord injury by inhibiting apoptosis and inflammation in mice
withaferin Aย regulates LRRK2 levels by interfering with the Hsp90-Cdc37 chaperone complex
withaferin Aย Regulates Muller Glial Cell Cycle During Retinal Gliosis
withaferin Aย reverses bile duct ligationโinduced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFฮบB signaling
withaferin Aย sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
withaferin Aย strongly elicits IฮบB kinase ฮฒ hyperphosphorylation concomitant with potent inhibition of its kinase activity
withaferin Aย suppresses and inhibits hepatocellular carcinoma-cell proliferation and tumor burden via activation of ERK1/2-ELK1-RSK-DR5 axis
withaferin Aย suppresses anti-apoptotic BCL2, Bcl-xL, XIAP and Survivin genes in cervical carcinoma cells
withaferin Aย suppresses Beta amyloid in APP expressing cells: Studies for Tat and Cocaine associated neurological dysfunctions
withaferin Aย suppresses estrogen receptorโฮฑ expression in human breast cancer cells
withaferin Aย suppresses liver tumor growth in a nude mouse model by downregulation of cell signaling pathway leading to invasion and angiogenesis
withaferin Aย suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 transcription factor
withaferin Aย suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression
withaferin Aย suppresses the upโregulation of acetylโcoA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse model
withaferin Aย suppresses tumor promoter 12โOโtetradecanoylphorbol 13โacetateโinduced decreases in isocitrate dehydrogenase 1 activity and mitochondrial function โฆ
withaferin Aย synergistically enhances the effects of paclitaxel against lung cancer.
withaferin Aย synergizes the therapeutic effect of doxorubicin through ROS-mediated autophagy in ovarian cancer
withaferin Aย targeting both cancer stem cells and metastatic cancer stem cells in the UP-LN1 carcinoma cell model
withaferin Aย targets apoptosis inhibitor cIAP1: A potential anticancer candidate
withaferin Aย targets heat shock protein 90 in pancreatic cancer cells
withaferin Aย targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis
withaferin Aย triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4โATF3โCHOP axis
withaferin A, a constituent of Indian Ayurvedic medicinal plant Withania somnifera, causes G2 phase and mitotic arrest in human breast cancer cells
withaferin A, a Cytotoxic Steroid from Vassobia breviflora, Induces Apoptosis in Human Head and Neck Squamous Cell Carcinoma
withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPฮฒ
withaferin A, a novel compound of Indian ginseng (Withania somnifera), ameliorates Ceruleinโinduced acute pancreatitis: Possible role of oxidative stress and โฆ
withaferin A, a potent and abundant component of Withania somnifera root extract, reduces myeloid-derived suppressor cell function (P2103)
withaferin A, a potent and abundant component of Withania somnifera root extract, reduces myeloid-derived suppressor cell function.
withaferin A, a Potential Regulator of Astrocyte Reactivity
withaferin A, a Steroidal Lactone from Withania somnifera, Induces Mitotic Catastrophe and Growth Arrest in Prostate Cancer Cells
withaferin A: a new radiosensitizer from the Indian medicinal plant Withania somnifera
withaferin A: A NOVEL THERAPEUTIC APPROACH FOR MALIGANT BRAIN TUMORS
withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone
withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug
withaferin AโA Phytosteroid of Promise for Tumour Sensitization in Cancer Therapy
withaferin A-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes
withaferin A-induced apoptosis in human breast cancer cells is associated with suppression of inhibitor of apoptosis family protein expression
withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species
withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics
withaferin A-mediated inhibition of breast carcinoma involves concomitant activation of CHOP and Elk1 via ERK/ribosomal S6 kinase (RSK) signaling axis regulating โฆ
withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells
withaferin A-stimulated Ca2+ entry, ceramide formation and suicidal death of erythrocytes
Withaferin-Aย as a Potential Candidate for Cancer Therapy: Experimental Evidence of Its Effects on Telomerase Plus and Minus Cancer Cells
Withaferin-Aย attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes
Withaferin-Aย displays enhanced anxiolytic efficacy without tolerance in rats following sub chronic administration
Withaferin-Aย in Ameliorating the Effects of High Glucose on Inflammatory and Phagocytic Response of Mouse Macrophages.
Withaferin-Aย induces apoptosis in osteosarcoma U2OS cell line via generation of ROS and disruption of mitochondrial membrane potential
Withaferin-Aย inhibits colon cancer cell growth by blocking STAT3 transcriptional activity
Withaferin-Aย Inhibits Growth of Drug-Resistant Breast Carcinoma by Inducing Apoptosis and Autophagy, Endogenous Reactive Oxygen Species (ROS) โฆ
Withaferin-Aย inhibits prostate tumor growth by enhancing anti-tumor immune response
Withaferin-Aย isolated from the cell cultures of Withania somnifera
Withaferin-Aย isolated from the cell cultures of Withania somnifera.
Withaferin-Aย kills cancer cells with and without telomerase: chemical, computational and experimental evidences
Withaferin-Aย reduces acetaminophen-induced liver injury in mice
Withaferin-Aย reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo
Withaferin-Aย suppress AKT induced tumor growth in colorectal cancer cells
Withaferin-A, a steroidal lactone encapsulated mannose decorated liposomes ameliorates rheumatoid arthritis by intriguing the macrophage repolarization in adjuvant โฆ
Withaferin-A: A Potential Anticancer Withanolide from Withania somnifera (L.) Dun.
Withaferin-AโA natural anticancer agent with pleitropic mechanisms of action
Withania somnifera (Ashwagandha) andย withaferin A: Potential in integrative oncology
Withania somnifera chemotypes NMITLI 101R, NMITLI 118R, NMITLI 128R andย withaferin Aย protect Mastomys coucha from Brugia malayi infection
Withania somnifera Extract/withaferin Aย as a Prospective Anti-pigmenting Agent
WITHDRAWN: Anti-tumor and proapoptotic effect ofย withaferin Aย is mediated by up-regulation of Bax and inhibition NF-ฮบB in Ehrlich ascites tumor cells
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