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Thiazolidinediones
Thiazolidinediones
Thiazolidinediones
Nonhypoglycemic effects of thiazolidinediones
Thiazolidinediones
Thiazolidinediones: an update
The mode of action of thiazolidinediones
Metabolic and additional vascular effects of thiazolidinediones
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
How safe is the use of thiazolidinediones in clinical practice?
Unraveling the mechanism of action of thiazolidinediones
Insulin resistance and its treatment by thiazolidinediones.
A meta-analysis comparing the effect of thiazolidinediones on cardiovascular risk factors
Use of thiazolidinediones and fracture risk
Thiazolidinediones as anti-cancer agents
Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence
Effect of thiazolidinediones on body weight in patients with diabetes mellitus
Thiazolidinediones and fractures in men and women
Thiazolidinediones: a new class of antidiabetic drugs
Thiazolidinediones and liver toxicity.
Protection of the kidney by thiazolidinediones: an assessment from bench to bedside
Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis
Thiazolidinediones: a 2010 perspective
Thiazolidinediones: effects on insulin resistance and the cardiovascular system
Thiazolidinediones and cardiovascular outcomes in older patients with diabetes
Pleiotropic effects of thiazolidinediones
The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones
Hepatotoxicity with thiazolidinediones: is it a class effect?
Hepatotoxicity of the thiazolidinediones
Thiazolidinediones-mechanisms of action
Thiazolidinediones and blood lipids in type 2 diabetes
Thiazolidinediones and heart failure: a teleo-analysis
Thiazolidinediones: metabolic actions in vitro
Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes
The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
Thiazolidinediones and inflammation
Mechanisms by which thiazolidinediones enhance insulin action
Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies
The safety of thiazolidinediones
Considerations for management of fluid dynamic issues associated with thiazolidinediones
Effect of thiazolidinediones on albuminuria and proteinuria in diabetes: a meta-analysis
Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study
Hepatotoxicity of thiazolidinediones
Thiazolidinediones and the risk of edema: a meta-analysis
Thiazolidinediones: a comparative review of approved uses
Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes
Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells
Thiazolidinediones, peripheral edema, and type 2 diabetes: incidence, pathophysiology, and clinical implications
Thiazolidinediones improve β-cell function in type 2 diabetic patients
The effect of thiazolidinediones on BMD and osteoporosis
Thiazolidinediones for the treatment of type 2 diabetes
Visfatin is an adipokine, but it is not regulated by thiazolidinediones
Pharmacokinetic interactions with thiazolidinediones
Thiazolidinediones and fractures: evidence from translating research into action for diabetes
Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones
Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling.
Thiazolidinediones as anti‐inflammatory and anti‐atherogenic agents
Thiazolidinediones: the case for early use
PPARγ-independent antitumor effects of thiazolidinediones
The role of thiazolidinediones in non-alcoholic steatohepatitis–a systematic review and meta analysis
New drugs for the treatment of diabetes mellitus: part I: Thiazolidinediones and their evolving cardiovascular implications
Thiazolidinediones–some recent developments
Thiazolidinediones, insulin resistance and obesity: finding a balance
Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity
Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues
Mechanisms and clinical effects of thiazolidinediones
Effectiveness and side effects of thiazolidinediones for type 2 diabetes: real‐life experience from a tertiary hospital
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.
Thiazolidinediones: a plethro of biological load
Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study
Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
Effects of thiazolidinediones on bone loss and fracture
Second-generation thiazolidinediones and hepatotoxicity
Recent findings concerning thiazolidinediones in the treatment of diabetes
Thiazolidinediones and heart failure
Thiazolidinediones and the liver in humans
Bone loss in diabetes: use of antidiabetic thiazolidinediones and secondary osteoporosis
Thiazolidinediones today
Effects of thiazolidinediones on differentiation, proliferation, and apoptosis
A meta‐analysis of the effect of thiazolidinediones on blood pressure
Effects of thiazolidinediones and sulfonylureas in patients with diabetes
Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?
Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
Therapeutic potential of thiazolidinediones as anticancer agents
Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells
Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition
Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.
Redefining the role of thiazolidinediones in the management of type 2 diabetes
The effect of thiazolidinediones on adiponectin serum level: a meta‐analysis
The Structure− Activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones
Effective use of thiazolidinediones for the treatment of glucocorticoid-induced diabetes
Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones
Thiazolidinediones and type 2 diabetes: new drugs for an old disease
Thiazolidinediones and cardiovascular risk—a question of balance
Reassessing the cardiovascular risks and benefits of thiazolidinediones
Comparison of effects of thiazolidinediones on cardiovascular risk factors: observations from a clinical practice
Thiazolidinediones regulate adipose lineage dynamics
Association between cancer prevalence and use of thiazolidinediones: results from the Vermont Diabetes Information System
Thiazolidinediones ameliorate diabetic nephropathy via cell cycle–dependent mechanisms
Thiazolidinediones and fracture risk in patients with type 2 diabetes
Clinical efficacy of new thiazolidinediones and glinides in the treatment of type 2 diabetes mellitus
Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes
A cohort study of thiazolidinediones and fractures in older adults with diabetes
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
Thiazolidinediones and antiblastics in primary human anaplastic thyroid cancer cells
The risk of fractures associated with thiazolidinediones: a self-controlled case-series study
Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells.
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
Thiazolidinediones, peripheral oedema and congestive heart failure: what is the evidence?
Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers
Thiazolidinediones in diabetes: current status and future outlook.
Recent thiazolidinediones as antidiabetics
Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic …
Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs
The effects of thiazolidinediones on blood pressure levels–a systematic review
Effects of thiazolidinediones on stroke recovery: a case-matched controlled study
Effects of thiazolidinediones beyond glycaemic control
The controversial effects of thiazolidinediones on cardiovascular morbidity and mortality
Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones
Down regulation of peroxisome proliferator-activated receptorγ expression by inflammatory cytokines and its reversal by thiazolidinediones
Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation
Regulation of triglyceride metabolism by PPARs: fibrates and thiazolidinediones have distinct effects
Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products
Effectiveness and long-term safety of thiazolidinediones and metformin in renal transplant recipients
Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability
Trans-differentiation of myoblasts to adipoblasts: triggering effects of fatty acids and thiazolidinediones
Mechanisms of action of thiazolidinediones
Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones
Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture
Thiazolidinediones and glucocorticoids synergistically induce differentiation of human adipose tissue stromal cells: biochemical, cellular, and molecular analysis
Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: A population based case-control study
The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact
Thiazolidinediones in dermatology
Thiazolidinediones and insulin resistance: Peroxisome proliferatoractivated receptor γ activation stimulates expression of the CAP gene
Synthesis and biological activity of novel acridinylidene and benzylidene thiazolidinediones
Structure–activity relationships and molecular modelling of 5-arylidene-2, 4-thiazolidinediones active as aldose reductase inhibitors
Synthesis and biological activity of novel thiazolidinediones
Energy restriction as an antitumor target of thiazolidinediones
Discovery of 5-aryloxy-2, 4-thiazolidinediones as potent GPR40 agonists
Cardiovascular risk and thiazolidinediones—what do meta‐analyses really tell us?
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions …
Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents
Novel phthalazinone and benzoxazinone containing thiazolidinediones as antidiabetic and hypolipidemic agents
Thiazolidinediones and risk of heart failure in patients with or at high risk of type 2 diabetes mellitus: a meta-analysis and meta-regression analysis of placebo …
The preventive anti‐oxidant action of thiazolidinediones: a new therapeutic prospect in diabetes and insulin resistance
β-cell preservation with thiazolidinediones
Effects of thiazolidinediones on blood pressure
Thiazolidinediones for initial treatment of type 2 diabetes?
Response of experimental retinal neovascularization to thiazolidinediones
Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones
Thiazolidinediones for treatment of polycystic ovary syndrome
Beyond peroxisome proliferator-activated receptor γ signaling: the multi-facets of the antitumor effect of thiazolidinediones
Thiazolidinediones: a review of their mechanisms of insulin sensitization, therapeutic potential, clinical efficacy, and tolerability
Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients
Thiazolidinediones and their fluid-related adverse effects: facts, fiction and putative management strategies
Rationale for and role of thiazolidinediones in type 2 diabetes mellitus
Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway
Progress with thiazolidinediones in the management of type 2 diabetes mellitus
Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3β-hydroxysteroid dehydrogenase
Thiazolidinediones as therapy for endometriosis: a case series
Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells
A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells
Thiazolidinediones on PPARγ: The Roles in Bone Remodeling
Thiazolidinediones and fertility in polycystic ovary syndrome (PCOS)
A review of thiazolidinediones and metformin in the treatment of type 2 diabetes with focus on cardiovascular complications
Thiazolidinediones in the treatment of type 2 diabetes
A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone
The role of thiazolidinediones in the treatment of patients with type 2 diabetes mellitus
Synthesis, characterization and antimicrobial activity evaluation of new 2, 4-Thiazolidinediones bearing imidazo [2, 1-b][1, 3, 4] thiadiazole moiety
A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus
Regulation of lipoprotein metabolism by thiazolidinediones occurs through a distinct but complementary mechanism relative to fibrates
Metformin vs thiazolidinediones for treatment of clinical, hormonal and metabolic characteristics of polycystic ovary syndrome: a meta‐analysis
Management of co-existing diabetes mellitus and dyslipidemia: defining the role of thiazolidinediones
Thiazolidinediones and clinical outcomes in type 2 diabetes
Long-term use of thiazolidinediones and the associated risk of pneumonia or lower respiratory tract infection: systematic review and meta-analysis
β-Cell rejuvenation with thiazolidinediones
Drug insight: thiazolidinediones and diabetic nephropathy—relevance to renoprotection
the treatment of non‐alcoholic steatohepatitis with thiazolidinediones
Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms
Addressing the insulin resistance syndrome: a role for the thiazolidinediones
Peroxisome proliferator-activated receptor γ-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells
Dual PPAR-α and-γ activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential
Thiazolidinediones in type 2 diabetes: a cardiology perspective
The potential of antidiabetic thiazolidinediones for anticancer therapy
Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells
Thiazolidinediones (PPARγ agonists) but not PPAR α agonists increase IRS‐2 gene expression in 3T3‐L1 and human adipocytes1
Thiazolidinediones suppress endothelin-1 secretion from bovine vascular endothelial cells: a new possible role of PPARγ on vascular endothelial function
Central role of the adipocyte in the insulin-sensitising and cardiovascular risk modifying actions of the thiazolidinediones
Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: a possible role for PPARγ in endothelial …
The cardiovascular effects of the thiazolidinediones: a review of the clinical data
Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes
Adiponectin gene activation by thiazolidinediones requires PPARγ2, but not C/EBPα—evidence for differential regulation of the aP2 and adiponectin genes
Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment
Thiazolidinediones: pleiotropic drugs with potent anti-inflammatory properties for tissue protection
Thiazolidinediones are partial agonists for the glucocorticoid receptor
Thiazolidinediones for nonalcoholic steatohepatitis—promising but not ready for prime time
Pleiotropic effects of thiazolidinediones on traditional and non‐traditional atherosclerotic risk factors
Thiazolidinediones Inhibit Osteoclast-Like Cell Formation and Bone Resorption in Vitro
Role of PPAR-γ agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: a cardiovascular perspective
Section review: oncologic, endocrine & metabolic: thiazolidinediones
Effects of the thiazolidinediones on cardiovascular risk factors
Thiazolidinediones: do harms outweigh benefits?
Thiazolidinediones: a review of their benefits and risks
Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis
Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression
Thiazolidinediones inhibit growth and invasiveness of the human adrenocortical cancer cell line H295R
Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells
[[. omega.-(Heterocyclylamino) alkoxy] benzyl]-2, 4-thiazolidinediones as potent antihyperglycemic agents
Thiazolidinediones reduce pathological neovascularization in ischemic retina via an adiponectin-dependent mechanism
Thiazolidinediones, peroxisome proliferator-activated receptor γ agonists, regulate endothelial cell growth and secretion of vasoactive peptides
Synthesis, biological evaluation and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities
The new clinical trials with thiazolidinediones–DREAM, ADOPT, and CHICAGO: promises fulfilled?
Topical treatment with thiazolidinediones, activators of peroxisome proliferator‐activated receptor‐γ, normalizes epidermal homeostasis in a murine hyperproliferative …
Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4
Thiazolidinediones: beyond glycemic control
Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model
Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in …
Do thiazolidinediones cause heart failure? A critical review.
Thiazolidinediones: novel treatments for cognitive deficits in mood disorders?
Thiazolidinediones: a pharmacological overview
Thiazolidinediones inhibit TNFα induction of PAI-1 independent of PPARγ activation
Thiazolidinediones inhibit the expression of beta3-adrenergic receptors at a transcriptional level.
Cardiovascular effects of the thiazolidinediones
β‐cell preservation: a potential role for thiazolidinediones to improve clinical care in Type 2 diabetes
Factors associated with results and conclusions of trials of thiazolidinediones
Vascular reactivity and thiazolidinediones
Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1α gene transcription: an autoregulatory loop controls PGC-1α …
The molecular mechanisms underlying the proinflammatory actions of thiazolidinediones in human macrophages
PPARγ activation by thiazolidinediones (TZDs) may modulate breast carcinoma outcome: the importance of interplay with TGFβ signalling
Administration of thiazolidinediones for neuroprotection in ischemic stroke: a pre‐clinical systematic review
Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase
Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones
The potential role of thiazolidinediones in atrial fibrillation
A placebo‐controlled trial of exenatide twice‐daily added to thiazolidinediones alone or in combination with metformin
Evaluation of the sensitivity to chemotherapeutics or thiazolidinediones of primary anaplastic thyroid cancer cells obtained by fine-needle aspiration
Antiatherogenic effects of thiazolidinediones?
Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy
Thiazolidinediones in patients with type 2 diabetes mellitus and heart failure
Fluid retention with thiazolidinediones: does the mechanism influence the outcome?
Role of PPAR in the pharmacological regulation of lipoprotein metabolism by fibrates and thiazolidinediones
Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone
Thiazolidinediones upregulate impaired fatty acid uptake in skeletal muscle of type 2 diabetic subjects
Pro-inflammatory properties for thiazolidinediones
Thiazolidinediones and type 2 diabetes: from cellular targets to cardiovascular benefit
Thiazolidinediones increase the wingless-type MMTV integration site family (WNT) inhibitor Dickkopf-1 in adipocytes: a link with osteogenesis
Combination therapy using metformin or thiazolidinediones and insulin in the treatment of diabetes mellitus
Thiazolidinediones: new evidence of bone loss
Fracture risk a class effect of thiazolidinediones in women
Pleiotropic actions of PPARg activators thiazolidinediones in cardiovascular diseases
Thiazolidinediones: a novel class of drugs for the prevention of diabetic nephropathy?
Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 …
Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats
The effects of fibrates and thiazolidinediones on plasma triglyceride metabolism are mediated by distinct peroxisome proliferator activated receptors (PPARs)
Thiazolidinediones stimulate uncoupling protein-2 expression in cell lines representing white and brown adipose tissues and skeletal muscle
Thiazolidinediones downregulate stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes
Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor
Meta-analysis of the effect of thiazolidinediones on serum C-reactive protein levels
Thiazolidinediones and risk of repeat target vessel revascularization following percutaneous coronary intervention: a meta-analysis
Cardiovascular risk and the thiazolidinediones: déjà vu all over again?
Thiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPARγ agonism
Comparison of the antidiabetic effects of brain‐derived neurotrophic factor and thiazolidinediones in obese diabetic mice
Thiazolidinediones and cardiovascular events in patients with type 2 diabetes mellitus: a retrospective cohort study of over 473 000 patients using the National Health …
Thiazolidinediones—benefits on microvascular complications of type 2 diabetes
Effect of thiazolidinediones on skeletal health in women with Type 2 diabetes
Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent nongenomic signaling
Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner
Insulin sensitizing pharmacology of thiazolidinediones correlates with mitochondrial gene expression rather than activation of PPARγ
Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin
Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats
Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects
Thiazolidinediones decrease vascular endothelial growth factor (VEGF) production by human luteinized granulosa cells in vitro
Thiazolidinediones: effects on the development and progression of type 2 diabetes and associated vascular complications
Thiazolidinediones-the new insulin enhancers
Insulin resistance and the effects of thiazolidinediones on cardiac metabolism
Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer
Thiazolidinediones and the risk of incident congestive heart failure among patients with type 2 diabetes mellitus
Thiazolidinediones plus metformin association on body weight in patients with type 2 diabetes
Thiazolidinediones: clinical data and perspectives
Thiazolidinediones and their effects on glucose transporters
Thiazolidinediones as a novel class of algicides against red tide harmful algal species
The thiazolidinediones rosiglitazone and pioglitazone and the risk of coronary heart disease: a retrospective cohort study using a US health insurance database
Thiazolidinediones for the prevention of diabetes in the non‐obese diabetic (NOD) mouse: implications for human type 1 diabetes
Thiazolidinediones and bone
Hypoglycemic Action of Thiazolidinediones/Peroxisome Proliferator–Activated Receptor γ by Inhibition of the c-Jun NH2-Terminal Kinase Pathway
Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of …
A “futile cycle” induced by thiazolidinediones in human adipose tissue?
Where thiazolidinediones will fit
Differential effect of the antidiabetic thiazolidinediones troglitazone and pioglitazone on human platelet aggregation mechanism.
The influence of thiazolidinediones on adipogenesis in vitro and in vivo: Potential modifiers of intramuscular adipose tissue deposition in meat animals,
Thiazolidinediones inhibit hepatocarcinogenesis in hepatitis B virus–transgenic mice by peroxisome proliferator‐activated receptor γ–independent regulation of …
Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data
Leukopenia and thrombocytopenia caused by thiazolidinediones
The roles of insulin resistance, hyperinsulinemia, and thiazolidinediones in cardiovascular disease
Lipoprotein effects of different thiazolidinediones in clinical practice
Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes
Investigation of the lipophilic behaviour of some thiazolidinediones: Relationships with PPAR-γ activity
Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARγ-dependent and PPARγ-independent pathways
Rapid racemization in thiazolidinediones: a quantum chemical study
Thiazolidinediones inhibit insulin-like growth factor-I–induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity
Effect of thiazolidinediones on bile acid transport in rat liver
Novel actions of thiazolidinediones on vascular function and exercise capacity
Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance
Evaluation of proinflammatory cytokines and inflammation markers as biomarkers for the action of thiazolidinediones in Type 2 diabetes mellitus patients and healthy …
Synthesis of 5-arylidene-2, 4-thiazolidinediones by Knoevenagel condensation catalyzed by baker’s yeast
3T3‐L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator‐activated receptor‐γ‐dependent and mediated by the caspase‐3‐dependent …
Substituted thiazolidinediones and thio-imidazolidinones: synthesis, structural study and pharmacological activity.
Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion
Synthesis of new pyrazolyl-2, 4-thiazolidinediones as antibacterial and antifungal agents
Is weight loss possible in patients treated with thiazolidinediones? Experience with a low-calorie diet
Peroxisome proliferator-activated receptor γ-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein …
Insulin-sensitizing agents–thiazolidinediones (glitazones)
Effects of retinoids and thiazolidinediones on proliferation, insulin release, insulin mRNA, GLUT 2 transporter protein and mRNA of INS‐1 cells
Effects of sulfonylureas on peroxisome proliferator-activated receptor γ activity and on glucose uptake by thiazolidinediones
Metformin, but not thiazolidinediones, inhibits plasminogen activator inhibitor-1 production in human adipose tissue in vitro
Synthetic thiazolidinediones: potential antidiabetic compounds
Mechanism for antioxidative effects of thiazolidinediones in pancreatic β-cells
Thiazolidinediones inhibit lipoprotein lipase activity in adipocytes
Approach to the management of diabetic patients with heart failure: role of thiazolidinediones
Thiazolidinediones for the treatment in NASH: sustained benefit after drug discontinuation?
Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of β-transducin repeat-containing protein
Effects of thiazolidinediones on growth and differentiation of human aorta and coronary myocytes
Risk of cardiovascular events and all-cause mortality in patients treated with thiazolidinediones in a managed-care population
Monogenic polycystic ovary syndrome due to a mutation in the lamin A/C gene is sensitive to thiazolidinediones but not to metformin
Thiazolidinediones: comparison of long-term effects on glycemic control and cardiovascular risk factors
Thiazolidinediones downregulate Wnt/β-catenin signaling via multiple mechanisms in breast cancer cells
Chronic and acute effects of thiazolidinediones BM13. 1258 and BM15. 2054 on rat skeletal muscle glucose metabolism
Thiazolidinediones and hepatic fibrosis: don’t wait too long
The effects of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II
Thiazolidinediones in type 2 diabetes. Role of peroxisome proliferator-activated receptor gamma (PPARgamma)
Thiazolidinediones, dyslipidaemia and insulin resistance syndrome
A selective peroxisome proliferator-activated receptor-γ modulator, telmisartan, binds to the receptor in a different fashion from thiazolidinediones
PEROXISOME PROLIFERATOR‐ACTIVATED RECEPTOR γ‐INDEPENDENT EFFECTS OF THIAZOLIDINEDIONES ON HUMAN CARDIAC MYOFIBROBLAST …
Effect of thiazolidinediones on expression of UCP2 and adipocyte markers in human PAZ6 adipocytes
Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor γ for monocyte recruitment and endothelial regeneration
Thiazolidinediones for NASH—one pill doesn’t fix everything
Thiazolidinediones as a novel class of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
Cost‐Effectiveness Analysis of Thiazolidinediones in Uncontrolled Type 2 Diabetic Patients Receiving Sulfonylureas and Metformin in Thailand
The effects of thiazolidinediones on metabolic complications and lipodystrophy in HIV-infected patients
Thiazolidinediones and bone fractures
Thiazolidinediones are novel insulin-sensitizing agents
Peroxisome proliferator-activated receptor γ-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells
Regulation of glyceroneogenesis and phosphoenolpyruvate carboxykinase by fatty acids, retinoic acids and thiazolidinediones: potential relevance to type 2 diabetes
Thiazolidinediones in patients with diabetes mellitus and heart failure: implications of emerging data
Antagonistic effects of thiazolidinediones and cytokines in lipotoxicity
Thiazolidinediones: potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease
Insulin resistance, diabetes, and atherosclerosis: thiazolidinediones as therapeutic interventions
Thiazolidinediones inhibit apoptosis and heat shock protein 60 expression in human vascular endothelial cells
Effect of thiazolidinediones on in-stent restenosis in patients after coronary stenting: a meta-analysis of randomized controlled trials
Thiazolidinediones—improving endothelial function and potential long-term benefits on cardiovascular disease in subjects with type 2 diabetes
Cellular and molecular effects of thiazolidinediones on bone cells: a review
Differential effects of peroxisome proliferator activated receptor-γ (PPARγ) ligands in proximal tubular cells: Thiazolidinediones are partial PPARγ agonists
Beneficial effects of thiazolidinediones on diabetic nephropathy in OLETF rats
Synthesis and biological evaluation of novel pyrazolyl-2, 4-thiazolidinediones as anti-inflammatory and neuroprotective agents
Thiazolidinediones are potent inducers of fibroblast growth factor 21 expression in the liver
Antidiabetic thiazolidinediones induce ductal differentiation but not apoptosis in pancreatic cancer cells
Thiazolidinediones, deadly sins, surrogates, and elephants
Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein
Effect of thiazolidinediones on high-density lipoprotein subfractions
The anti-atherogenic effects of thiazolidinediones
Stimulation of resorption in cultured mouse calvarial bones by thiazolidinediones
Clinical use of thiazolidinediones: recommendations
Effects of thiazolidinediones on glucocorticoid-induced insulin resistance and GLUT4 glucose transporter expression in rat skeletal muscle
Do thiazolidinediones cause congestive heart failure?
Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical …
Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells
Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle
Thiazolidinediones: a new class of drugs for the therapy of ischemia-reperfusion injury.
Clinical trials with thiazolidinediones in subjects with Type 2 diabetes–is pioglitazone any different from rosiglitazone?
Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism
Nonhypoglycemic effects of thiazolidinediones
Thiazolidinediones and fluid retention
An overview of the beneficial cardiovascular effects of thiazolidinediones
Synthesis of peptides in aqueous medium. VII. Preparation and use of 2, 5-thiazolidinediones in peptide synthesis
The association between thiazolidinediones and hospitalisation for fracture in type 2 diabetic patients: a Taiwanese population-based nested case–control …
Thiazolidinediones in prediabetes and early type 2 diabetes: what can be learned about that disease’s pathogenesis
Alteration in expression profiles of a series of diabetes-related genes in db/db mice following treatment with thiazolidinediones
The emerging role of thiazolidinediones in the treatment of diabetes-mellitus and related disorders
Differential effects among thiazolidinediones on the transcription of thromboxane receptor and angiotensin II type 1 receptor genes
Novel benzoxazole 2, 4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships
Cytotoxic effects of statins and thiazolidinediones on meningioma cells
2, 4-Thiazolidinediones as potent and selective human β3 agonists
The effect of thiazolidinediones on bone mineral density in Chinese older patients with type 2 diabetes
Risk of acute myocardial infarction in patients treated with thiazolidinediones or other antidiabetic medications
… of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: update regarding thiazolidinediones: a consensus statement …
Synthesis and aldose reductase inhibitory activity of 5-arylidene-2, 4-thiazolidinediones
Thiazolidinediones and vascular damage
Thiazolidinediones and the preservation of β‐cell function, cellular proliferation and apoptosis
Can thiazolidinediones delay disease progression in type 2 diabetes?
Use of thiazolidinediones in HIV-infected patients: what have we learned?
Insulin-sensitising agents: beyond thiazolidinediones
Mechanism of action of thiazolidinediones.
Different effects of thiazolidinediones on cardiovascular risk in patients with type 2 diabetes mellitus: pioglitazone vs rosiglitazone
Thiazolidinediones Induce Rab7–RILP–MAPK‐Dependent Juxtanuclear Lysosome Aggregation and Reduce Tumor Cell Invasion
Inhibition of TGF-β expression: a novel role for thiazolidinediones to implement renoprotection in diabetes
Thiazolidinediones and the risk of incident strokes in patients with type 2 diabetes: a nested case‐control study
Three-dimensional quantitative structure-activity relationships (3D-QSAR) of antidiabetic thiazolidinediones.
Adverse events with concomitant use of simvastatin or atorvastatin and thiazolidinediones
The role of the thiazolidinediones in the practical management of patients with type 2 diabetes and cardiovascular risk factors.
Long‐term glycaemic efficacy and weight changes associated with thiazolidinediones when added at an advanced stage of type 2 diabetes
Thiazolidinediones inhibit REG Iα gene transcription in gastrointestinal cancer cells
Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats
Thiazolidinediones may contribute to the intramyocardial lipid accumulation in diabetic myocardium: effects on cardiac function
Quantitative structure–activity analysis of 5-arylidene-2, 4-thiazolidinediones as aldose reductase inhibitors
Thiazolidinediones for the therapeutic management of polycystic ovary syndrome: impact on metabolic and reproductive abnormalities
Treating insulin resistance in type 2 diabetes with metformin and thiazolidinediones
C‐reactive protein, its role in inflammation, type 2 diabetes and cardiovascular disease, and the effects of insulin‐sensitizing treatment with thiazolidinediones
Thiazolidinediones inhibit growth of gastrointestinal, biliary, and pancreatic adenocarcinoma cells through activation of the peroxisome proliferator-activated receptor γ …
Thiazolidinediones and cardiovascular events in high-risk patients with type-2 diabetes mellitus: a comparison with other oral antidiabetic agents
Thiazolidinediones and insulin: rationale for use and role of combination therapy in type 2 diabetes mellitus
Thiazolidinediones modulate the expression of β-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 …
Differential effects of thiazolidinediones on adipocyte growth and recruitment in Zucker fatty rats
Insights on distinct pathways of thiazolidinediones (PPARγ ligand)‐promoted apoptosis in TRAIL‐sensitive or‐resistant malignant urothelial cells
Studies on antidiabetic agents. Synthesis and hypoglycemic activity of 5-[4-(pyridylalkoxy) benzyl]-2, 4-thiazolidinediones.
Effects of thiazolidinediones for early treatment of type 2 diabetes mellitus
… review and meta‐analysis of controlled trials using carotid intima‐media thickness or pulse wave velocity to infer antiatherogenic properties of thiazolidinediones
Expression and characterization of recombinant rat acyl-CoA synthetases 1, 4, and 5: selective inhibition by triacsin C and thiazolidinediones
The thiazolidinediones or” glitazones” a treatment option for type 2 diabetes mellitus.
Could thiazolidinediones increase the risk of heart failure in Friedreich’s ataxia patients?
Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones
Thiazolidinediones increase hepatic insulin extraction in African Americans with impaired glucose tolerance and type 2 diabetes mellitus. A pilot study of rosiglitazone
Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ
Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor γ-independent pathway
… of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: Update regarding the thiazolidinediones
Effects of combination of thiazolidinediones with melatonin in dexamethasone-induced insulin resistance in mice
Targeting insulin resistance and β-cell dysfunction: the role of thiazolidinediones
15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells
Synthesis and biological activity of [[(heterocycloamino) alkoxy] benzyl]-2, 4-thiazolidinediones as PPARγ agonists
Thiazolidinediones inhibit alkaline phosphatase activity while increasing expression of uncoupling protein, deiodinase, and increasing mitochondrial mass in …
Thiazolidinediones and congestive heart failure—exacerbation or new onset of left ventricular dysfunction?
Role of Thiazolidinediones in the Management of Type 2 Diabetes
Thiazolidinediones (PPARγ ligands) increase IRS-1, UCP-2 and C/EBPα expression, but not transdifferentiation, in L6 muscle cells
Using thiazolidinediones: rosiglitazone and pioglitazone in clinical practice
Thiazolidinediones inhibit cell growth of human oral squamous cell carcinoma in vitro independent of peroxisome proliferator-activated receptor γ
Thiazolidinediones: potential link between insulin resistance and cardiovascular disease
Thiazolidinediones and congestive heart failure: a judicious balance of risks and benefits
Thiazolidinediones inhibit TNF-α-mediated osteoclast differentiation of RAW264. 7 macrophages and mouse bone marrow cells through downregulation of NFATC1
Insulin resistance, adipocyte biology, and thiazolidinediones: a review
BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones.
Short insulin tolerance test can determine the effects of thiazolidinediones treatment in type 2 diabetes
Effect of thiazolidinediones on equilibrative nucleoside transporter-1 in human aortic smooth muscle cells
Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study: response to Delea et al.
The use of optical coherence tomography to determine the effect of thiazolidinediones on retinal thickness in patients with type 2 diabetes
Thiazolidinediones and congestive heart failure in veterans with type 2 diabetes
Thiazolidinediones influence plasma steroids of male obese Zucker rats
Skeletal toxicity of thiazolidinediones
Thiazolidinediones, cardiovascular disease and cardiovascular mortality: translating research into action for diabetes (TRIAD)
Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of …
Adiponectin receptor gene expression in human skeletal muscle cells is not regulated by fibrates and thiazolidinediones
Comparison of metformin and thiazolidinediones in the management of polycystic ovary syndrome
Pyruvate dehydrogenase kinase 4: regulation by thiazolidinediones and implication in glyceroneogenesis in adipose tissue
Commentary: What can we learn from the continuing regulatory focus on the thiazolidinediones?
Thiazolidinediones and progression of renal disease in patients with diabetes
Thiazolidinediones with thyroid hormone receptor agonistic activity
Thiazolidinediones and cardiovascular outcomes in type 2 diabetes
Capacitative calcium entry contributes to the differential transactivation of the epidermal growth factor receptor in response to thiazolidinediones
NASH and thiazolidinediones: not to be taken lightly
Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones
Thiazolidinediones and diabetic nephropathy: need for a closer examination?
5-Arylidene-2, 4-thiazolidinediones as inhibitors of protein tyrosine phosphatases
Effect of thiazolidinediones on the erythropoeitic and germinal cells in the male wistar rats
Thiazolidinediones inhibit the progression of established hypertension in the Dahl salt-sensitive rat
In vitro aldose reductase inhibitory activity of 5-benzyl-2, 4-thiazolidinediones
Effect of thiazolidinediones on lipid profile
Cardiovascular disease and benefits of thiazolidinediones.
The impacts of thiazolidinediones on circulating C-reactive protein levels in different diseases: a meta-analysis
Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans
15-Deoxy-Δ12, 14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle …
Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones
Thiazolidinediones increase arachidonic acid release and subsequent prostanoid production in a peroxisome proliferator-activated receptor γ-independent manner
Thiazolidinediones and the influence of media adverse reporting on prescribing attitudes in practice (TZD‐IMPACT) study
Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity …
Pharmacological therapy for non‐alcoholic steatohepatitis: How efficient are thiazolidinediones?
Thiazolidinediones: antidiabetic drugs with cardiovascular effects
Solution-and solid-phase synthesis of peptide-substituted thiazolidinediones as potential PPAR ligands
Why might thiazolidinediones increase exercise capacity in patients with type 2 diabetes?
Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity
Electrophilic α-thiocyanation of chiral and achiral N-acyl imides. A convenient route to 5-substituted and 5, 5-disubstituted 2, 4-thiazolidinediones
The metabolic syndrome: evolving evidence that thiazolidinediones provide rational therapy
Point: recent long-term clinical studies support an enhanced role for thiazolidinediones in the management of type 2 diabetes
Thiazolidinediones inhibit the growth of PC12 cells both in vitro and in vivo
A meta-analysis on treatment effects of thiazolidinediones for type 2 diabetes mellitus in Asian populations
Thiazolidinediones prevent PDGF-BB-induced CREB depletion in pulmonary artery smooth muscle cells by preventing upregulation of casein kinase 2 α …
Glucocorticoids repress induction by thiazolidinediones, fibrates, and fatty acids of phosphoenolpyruvate carboxykinase gene expression in adipocytes
Cardiovascular effects of thiazolidinediones
Synthesis and structure of substituted bromo and nitrobenzyl benzylidene imidazolidinediones and thiazolidinediones
Thiazolidinediones exhibit different effects on preadipocytes isolated from rat mesenteric fat tissue and cell line 3T3‐L1 cells derived from mice
Evaluation of in vitro aldose redutase inhibitory activity of 5-arylidene-2, 4-thiazolidinediones
Relationship between cumulative dose of thiazolidinediones and clinical outcomes in type 2 diabetic patients with history of heart failure: a population‐based cohort …
Osteoprotegerin, thiazolidinediones treatment, and silent myocardial ischemia in type 2 diabetic patients
Thiazolidinediones and cardiovascular disease
Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and …
Synthesis of spirocyclic thiazolidinediones using ring-closing metathesis and one-pot sequential ring-closing/cross metathesis
Synthesis of O-prenylated and O-geranylated derivatives of 5-benzylidene2, 4-thiazolidinediones and evaluation of their free radical scavenging activity as well as …
Diffusion patterns of new anti-diabetic drugs into hospitals in Taiwan: the case of Thiazolidinediones for diabetes
New therapies in diabetes–thiazolidinediones
Impact of the socioeconomic status on the probability of receiving formulary restricted thiazolidinediones (TZDs)
Diabetes and heart failure: the role of thiazolidinediones in managing these partners in crime
Race, ethnicity, and use of thiazolidinediones among US adults with diabetes
Regiospecific reduction of 5-benzylidene-2, 4-thiazolidinediones and 4-oxo-2-thiazolidinethiones using lithium borohydride in pyridine and tetrahydrofuran
Bone metabolism in type 2 diabetes and role of thiazolidinediones
Synthesis of New 3‐(Substituted Phenacyl)‐5‐[3′‐(4H‐4‐oxo‐1‐benzopyran‐2‐yl)‐benzylidene]‐2,4‐thiazolidinediones and their Antimicrobial Activity
Novel PPARγ-dependent and independent effects for thiazolidinediones
Pharmaceutical penetration of new drug and pharmaceutical market structure in Taiwan: hospital-level prescription of thiazolidinediones for diabetes
Oral combination therapy with thiazolidinediones in type 2 diabetes.
Type 2 diabetes, psoriasis and thiazolidinediones
Do thiazolidinediones increase the risk of congestive heart failure and cardiovascular death?
Thiazolidinediones et insulino-sensibilité: rôle du récepteur nucléaire PPARγ
Skeletal effects of thiazolidinediones
Durability of glycemic control: a feature of the thiazolidinediones
3D-QSAR studies on a series of 5-arylidine-2, 4-thiazolidinediones as aldose reductase inhibitors: a self-organizing molecular field analysis approach
Thiazolidinediones increase the number of platelets in immune thrombocytopenic purpura mice via inhibition of phagocytic activity of the reticulo-endothelial system
Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis
Altering PPARγ ligand selectivity impairs adipogenesis by thiazolidinediones but not hormonal inducers
Synthesis and antihyperglycemic activity of novel 5-(naphthalenylsulfonyl)-2, 4-thiazolidinediones
Synthesis and biological activity of some new flavonyl-2, 4-thiazolidinediones
Thiazolidinediones–a new class of oral antidiabetic drugs
Effects of thiazolidinediones on cardiovascular risk factors
Medicaid managed care: disparities in the use of thiazolidinediones compared with metformin.
Down-regulation of uncoupling protein-3 and-2 by thiazolidinediones in C2C12 myotubes
Cardioprotective effects of thiazolidinediones, peroxisome proliferator-activated receptor-gamma agonists.
Thiazolidinediones: reactivity of the active methylene group
What evidence should guide the use of thiazolidinediones?
Novel euglycemic and hypolipidemic agents. 4. Pyridyl-and quinolinyl-containing thiazolidinediones
Thiazolidinediones: From antioxidant to neurotherapeutic?
Thiazolidinediones–a new class of oral antidiabetics
Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARγ-independent pathway in human aortic smooth muscle cells
Novel antidiabetic and hypolipidemic agents. 3. Benzofuran-containing thiazolidinediones
Self-organizing molecular field analysis of 2, 4-thiazolidinediones: A 3D-QSAR model for the development of human PTP1B inhibitors
Thiazolidinediones and the renal and hormonal response to water immersion-induced volume expansion in type 2 diabetes mellitus
Different effects of thiazolidinediones on target vessel revascularization with bare metal stents: a meta-analysis
Synthesis of peptides in aqueous medium. V. Preparation and use of 2, 5-thiazolidinediones (NTA’s). Use of the 13C-H nuclear magnetic resonance signal as …
Information on thiazolidinediones
QSAR study of 5-arylidene-2, 4-thiazolidinediones as aldose reductase inhibitors
Drug class review: Thiazolidinediones
Acute toxicity assessment of new algicides of thiazolidinediones derivatives, TD53 and TD49, using Ulva pertusa Kjellman
Thiazolidinediones and their effect on bone metabolism: a review
Thiazolidinediones and cardiovascular outcomes
Synthesis and antimicrobial activity of chlorobenzyl benzylidene imidazolidinedione derivatives and substituted thiazolidinediones
Thiazolidinediones and lowered HDL cholesterol
Synthesis and aldose reductase inhibitory activity of some new chromonyl-2, 4-thiazolidinediones
Thiazolidinediones in the treatment of managed care patients with type 2 diabetes
Efficient gene regulation by PPARγ and thiazolidinediones in skeletal muscle and heart
15-Deoxy-Δ12, 14-prostaglandin J2 and thiazolidinediones transactivate epidermal growth factor and platelet-derived growth factor receptors in vascular smooth …
Thiazolidinediones exert different effects on insulin resistance between dexamethasone-treated rats and wistar fatty rats
Current developments in thiazolidinediones
Thiazolidinediones for type 2 diabetes: no evidence exists that pioglitazone induces hepatic cytochrome P450 isoform CYP3A4
Rosiglitazone, thiazolidinediones and atherosclerosis
Restoration of impaired p38 activation by insulin in insulin resistant skeletal muscle cells treated with thiazolidinediones
Synthesis and hypoglycemic activity of some substituted flavonyl thiazolidinedione derivatives—fifth communication: flavonyl benzyl substituted 2, 4-thiazolidinediones
Are thiazolidinediones good or bad for the heart?
Use of a PPAR gamma-specific monoclonal antibody to demonstrate thiazolidinediones induce PPAR gamma receptor expression in vitro
Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.
The risk of coronary heart disease in type 2 diabetic patients exposed to thiazolidinediones compared to metformin and sulfonylurea therapy
Direct attenuation of plasminogen activator inhibitor type-1 expression in human adipose tissue by thiazolidinediones
Management of type 2 diabetes mellitus. Role of thiazolidinediones.
Thiazolidinediones and cardiovascular disease: balancing benefit and harm
An overview and comparison of the thiazolidinediones
Thiazolidinediones do not reduce target vessel revascularization in diabetic patients undergoing percutaneous coronary intervention
Regulation of CCAAT/Enhancer Binding Proteinα (C/EBPα) Gene Expression by Thiazolidinediones in 3T3-L1 Adipocytes
Synthesis and antidiabetic activity of some new chromonyl-2, 4-thiazolidinediones
Suspected suppression of the INR by thiazolidinediones: interaction between warfarin and TZDs
Clinical thiazolidinediones as PPARγ ligands with the potential for the prevention of cardiovascular disease in diabetes
Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma
Update on the Safety of Thiazolidinediones
Cardiovascular effects of thiazolidinediones: a review of the literature.
Type 2 diabetes, thiazolidinediones: bad to the bone?
Standardized reversed-phase thin-layer chromatographic study of the lipophilicity of five anti-diabetic thiazolidinediones
Association of diet alone, insulin, sulfonylureas, metformin, and thiazolidinediones with the severity of coronary artery disease in patients with diabetes mellitus
Improving cardiovascular risk–applying evidence‐based medicine to glucose‐lowering therapy with thiazolidinediones in patients with type 2 diabetes
Thiazolidinediones may be effective in the prevention of stent thrombosis with DES
Adiponectin and its response to thiazolidinediones are associated with insulin‐mediated glucose metabolism in type 2 diabetic patients and their first‐degree relatives
… and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12, 14-prostaglandin J2 and thiazolidinediones in breast cancer …
Diabetes mellitus, thiazolidinediones and fractures: an unfinished story
Sitagliptin compared with thiazolidinediones as a third-line oral antihyperglycemic agent in type 2 diabetes mellitus
Closing the gap between clinical research and clinical practice: can outcome studies with thiazolidinediones improve our understanding of type 2 diabetes?
Effects of thiazolidinediones on the triad of type 2 diabetes mellitus, insulin resistance and cardiovascular disease
Thiazolidinediones as PPAR agonists
Rearrangement of oxazolidinethiones to thiazolidinediones or thiazinanediones and their application for the synthesis of chiral allylic ureas and α-methyl-β-amino …
Mass spectrometry of some benzylidene imidazolidinediones and thiazolidinediones. II-chlorobenzyl imidazolidinedione and fluoro or chlorobenzyl thiazolidinedione …
Dicationic ionic liquid mediated synthesis of 5‐arylidine‐2, 4‐thiazolidinediones
Synthesis of Some Novel 5-Substituted Arylidene–2, 4–Thiazolidinediones as Bioactive Agents
c-Fos-driven transcriptional activation of transforming growth factor β-1: inhibition of high glucose-induced promoter activity by thiazolidinediones
Nuclear peroxisome proliferator-activated receptors and thiazolidinediones
Induction of plasminogen activator inhibitor‐1 (PAI‐1) gene expression in adipocytes by thiazolidinediones
Predictors of nonpersistence with thiazolidinediones in patients with type 2 diabetes
The risk of myopathy associated with thiazolidinediones and statins in patients with type 2 diabetes: a nested case-control analysis
Arterial elasticity and plasma levels of adiponectin and leptin in type 2 diabetic patients treated with thiazolidinediones
Use of thiazolidinediones does not affect prostate-specific antigen levels in men with diabetes
Thiazolidinediones may not reduce diabetes incidence in type 1 diabetes
Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study: response to Karter et al
Clinical indications for thiazolidinediones
Type 2 diabetes, thiazolidinediones, and cardiovascular risk
Conversion of C2C12 myoblast into adipoblast with thiazolidinediones-A possible basis for Intramuscular fat generation in meat animals
Myocardial 15-Epi-lipoxin A4 Generation Provides a New Mechanism for the Immunomodulatory Effects of Statins and Thiazolidinediones
Synthesis and antimicrobial evaluation of some 3-(substituted phenacyl)-5-[4′-(4H-4-oxo-1-benzopyran-2-yl)-benzylidene]-2, 4-thiazolidinediones
Are thiazolidinediones first-line agents?
Summarising the use of thiazolidinediones with insulin
Do thiazolidinediones harm skeletal integrity?
Studies on 4‐thiazolidinones. I. Cleavage of 3‐Phenyl‐2, 4‐thiazolidinediones with benzylamine and hydrazine
Design, synthesis and in vitro evaluation of a series thiazolidinediones analogs as PPAR modulators
Drug Class Review: Thiazolidinediones: Final Report Update 1
… metabolic syndrome and implications for the management of cardiovascular risk in type 2 diabetes with particular focus on the emerging role of the thiazolidinediones
The potentially inappropriate prescription of new drug: thiazolidinediones for patients with type II diabetes in Taiwan
Chiral N-(o-aryl)-thiazolidinediones: Synthesis from rhodanines and investigation on rotational enantiomers by NMR spectroscopy
Cardiovascular risk-benefit ratio of thiazolidinediones
Novel euglycemic and hypolipidemic agents: pyridine containing unsaturated thiazolidinediones
CoMFA and CoMSIA analysis of 2, 4-thiazolidinediones derivatives as aldose reductase inhibitors
Thiazolidinediones for dementia and mild cognitive impairment
Improvement of liver function parameters in patients with type 2 diabetes treated with thiazolidinediones
Thiazolidinediones in type 2 diabetes–have they lived up to expectations?
Thiazolidinediones anti-inflammatory and anti-atherosclerotic effects in type 2 diabetes mellitus
Thiazolidinediones alter growth and epithelial cell integrity, independent of PPAR-γ and MAPK activation, in mouse M1 cortical collecting duct cells
Receptor-independent metabolic effects of thiazolidinediones in astrocytes
Bypassing the side effects of thiazolidinediones?
Thiazolidinediones could improve endothelial dysfunction and risk of premature coronary heart disease in HIV-infected patients
Elevated vitamin D status in postmenopausal women on thiazolidinediones for type 2 diabetes
Studies on 4-thiazolidinones. IX, The conversion of 5-substituted 2-thioxo-4-thiazolidinones into corresponding 2, 4-thiazolidinediones
Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome
Synthesis of N-substituted 2, 4-thiazolidinediones from oxazolidinethiones
4‐Thiazolidinones and 2, 4‐thiazolidinediones from α‐mercaptopropionic acid and carbodiimides
5-Aralkylidene-3-isobutyl-2, 4-thiazolidinediones
Tissue triglyceride levels in type 2 diabetes and the role of thiazolidinediones in reversing the effects of tissue hypertriglyceridemia: review of the evidence in animals …
One-Pot Multicomponent Synthetic Route for New Quinolidinyl 2, 4-Thiazolidinediones
An observational study of the effect of two thiazolidinediones on blood lipid levels: Rosiglitazone and pioglitazone in routine clinical practice
The effect of thiazolidinediones on HDL subfractions
Ionic liquid-accelerated N-arylation of 5-arylidene-2, 4-thiazolidinediones with diaryliodonium salts
Clinical difference between thiazolidinediones and biguanides
Regulation of uncoupling protein-2 mRNA in L6 myotubules: I: Thiazolidinediones stimulate uncoupling protein-2 gene expression by a mechanism requiring ongoing …
The transcription factor Fos-related antigen 1 is induced by thiazolidinediones during differentiation of 3T3-L1 cells
Thiazolidinediones as potent inducers of hepatocyte growth factor
Thiazolidinediones and the risk of nontraumatic fractures in patients with diabetes
Effect of thiazolidinediones on insulin resistance and cardiovascular risk factors
Synthesis and antidiabetic activity of some new furochromonyl-2, 4-thiazolidinediones
Thiazolidinediones and salivary gland enlargement
Expression of uncoupling protein-3 mRNA in rat skeletal muscle is acutely stimulated by thiazolidinediones: an exercise-like effect?
Management of type 2 diabetes with thiazolidinediones: link between β-cell preservation and durability of response
Macular edema and thiazolidinediones
On the Reactivity of the Exocyclic Double Bond in 5-Arylidene-3-aryl-2, 4-thiazolidinediones; Their Reaction with Diazoalkanes, p-Thiocresol and Piperidine
Thiazolidinediones associated with recurrent pleural effusions post coronary artery bypass surgery
In vitro aldose reductase inhibitory activity of some flavonyl-2, 4-thiazolidinediones
Mass Spectrometry of Some Benzylidene Imidazolidinediones and Thiazolidinediones. III-Positive and Negative Electron Impact Mass Spectra of Chlorobenzyl …
Thiazolidinediones and PPARgamma system in repair of liver damage
Thiazolidinediones for elderly patients with Type 2 diabetes: safe or not?
Thiazolidinediones for Diabetes Mellitus: Considerations for Reimbursements by Third-Party Payors
Enhancing insulin action: From chemical elements to thiazolidinediones
Thiazolidinediones increased risk for heart failure, myocardial infarction, and death in older patients with type 2 diabetes
Constructing an algorithm for managing type 2 diabetes. Focus on role of the thiazolidinediones.
The thiazolidinediones: a new class of antidiabetic agents
Regulation of MMP-1 expression in vascular endothelial cells by insulin sensitizing thiazolidinediones
Improving management of type 2 diabetes mellitus: 5. Thiazolidinediones
Type 2 Diabetes: Uses of thiazolidinediones and insulin
Thiazolidinediones and cardiovascular risk: Will the evidence so far available modify treatment strategies for type 2 diabetes?
Thiazolidinediones in cardiovascular risk in type 2 diabetes mellitus
Effect of aspirin use on thiazolidinediones and cardiovascular events
Fractures, heart failure and fears of myocardial ischaemia: has the RECORD stuck for rosiglitazone and the thiazolidinediones?
Combination therapy of angiotensin receptor blocker with statin or thiazolidinediones as promising therapeutic strategy for metabolic syndrome and …
The effect of PPAR gamma agonists thiazolidinediones on eosinophil function
Thiazolidinediones and the risk of nontraumatic fractures in patients with diabetes: in reply
Thiazolidinediones could be an effective treatment for HIV-associated progressive multifocal leukoencephalopathy
Risk of heart failure with the use of thiazolidinediones within a medicaid population
A lesson in moderation: applying pharmacodynamics to clarify the relationship between thiazolidinediones and adverse vascular outcomes in type 2 diabetes
Thiazolidinediones increase fracture risk
American Diabetes Association 60th Scientific Sessions, 2000: thiazolidinediones, obesity, and related topics
How beneficial are thiazolidinediones for diabetes mellitus?
… Reagents. XXII. Action of Organomagnesium Compounds on 2-Mercapto-4-arylidene-5-thiazolidones and on 4-Arylidene-2, 5-thiazolidinediones. Reaction of 2 …
Detrimental action of thiazolidinediones on bone
Mass Spectrometry of Some Bromophenacyl Thiothiazolidinones and Thiazolidinediones
Incidence of cardiovascular events in which 2 thiazolidinediones are used as add-on treatments for type 2 diabetes mellitus in a Taiwanese population
Implication for thiazolidinediones (TZDs) as novel potential anti-inflammatory drugs
The place of thiazolidinediones in the treatment of type 2 diabetes
Substituted thiazolidinediones and thioxothiazolidinones: synthesis and structure
Effect of thiazolidinediones (TZDs) on endothelial cell growth and secretion of endothelium-derived vasoactive substances-potential protective action of TZDs on …
Unravelling the antidiabetic mechanisms of the thiazolidinediones
Thiazolidinediones and slowing the progression of diabetes.
Thiazolidinediones in peritoneal dialysis patients
Effects of thiazolidinediones on serum lipoproteins
The effects of thiazolidinediones on blood pressure control among different populations–a meta-analysis
Thiazolidinediones are not associated with increased risk of heart failure hospitalizations in ambulatory patients with diabetes mellitus and heart failure
Dyslipidemia in type 2 diabetes and the effects of thiazolidinediones
Association between the use of thiazolidinediones and the risk of cancer in diabetic patients
Activation of PPAR [Gamma] Inhibits Macrophage Proliferation and Migration: Possible Therapeutic Effectiveness of Thiazolidinediones on Diabetic Vascular …
Thiazolidinediones in NASH An Odd Couple Meant To Be?
What is the future of thiazolidinediones (TZDs) after market introduction of inhaled insulin?
Substituted imidazolidinediones and thiazolidinediones: synthesis, structure and cytotoxic activity
Combination of nateglinide with thiazolidinediones in Type 2 diabetes
Evaluation of Thiazolidinediones on Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus: A Systematic Review
Are thiazolidinediones associated with an increased risk of heart failure and cardiovascular death?
Modulation of cardiac fibroblast function by thiazolidinediones with a focus on the role of LOX-1.
Current management of type 2 diabetes: Why thiazolidinediones should be the cornerstone of therapy
Thiazolidinediones
Synthesis and antifungal activity of chlorobenzyl benzylidene thiazolidinediones and substituted of imidazolidinediones
The impact of thiazolidinediones on microalbuminuria in adults with type 2 diabetes mellitus: a systematic review
Thiazolidinediones regulate expression of proteins involved in triglyceride storage and fatty acid oxidation in 3T3-L1 pre-adipocytes
Thiazolidinediones in heart failure: slippery when wet
A Retrospective Review of Thiazolidinediones with Development of a Troglitazone Conversion Protocol
Synthesis and antihyperglycemic activity of novel flavonyl 2, 4-thiazolidinediones
Possible vascular-protective effects of antidiabetic agents such as the thiazolidinediones (TZDs).
Insulinotropic activity of chromonyl-2, 4-thiazolidinediones
Thiazolidinediones exert a hypotriglyceridemic effect by a distinct, but complementary mechanism relative to fibrates
Synthesis of polymeric thiazolidinediones and L-ascorbic acid towards the development of insulin-sensitizer
SYNTHESIS AND EVALUATION OF NEWER QUINOLINE DERIVATIVES OF THIAZOLIDINEDIONES FOR THEIR ANTIDIABETIC ACTIVITY L. SRIKANTH, N …
Organic reactions in ionic liquids: ionic liquid-accelerated facile synthesis of 3-alkyl-2, 4-thiazolidinediones
Drugs for diabetes: Part 3 thiazolidinediones
Antioxidative activities of thiazolidinediones and dihydropyridine-type calcium antagonists
Thiazolidinediones and the Risk of Incident Congestive Heart Failure Among Patients With Type 2 Diabetes Mellitus: A Population-Based Nested Case-Control Study
Information on thiazolidinediones
Trends in management of type 2 diabetes: role of thiazolidinediones
Thiazolidinediones—the Ongoing Debate
… of uncoupling protein-2 mRNA in L6 myotubules: II: thyroid hormone amplifies stimulation of uncoupling protein-2 gene by thiazolidinediones and other peroxisome …
Opposite effects of two thiazolidinediones, ciglitazone and troglitazone, on proteinase-activated receptor-1-triggered prostaglandin E2 release
Comparative study of thiazolidinediones in clinical use
Recent trends in PPARgamma agonist development of thiazolidinediones and non-thiazolidinediones
Thiazolidinediones: a long way to clinical practice
Thiazolidinediones and Bone
Proper usage of thiazolidinediones
Thiazolidinediones.(Medication Update)
Effects of Thiazolidinediones on Coronary Artery Disease
ADOPT: evidence for early use of thiazolidinediones
Thiazolidinediones and type 2 diabetes
Cardiovascular side effects of thiazolidinediones
Thiazolidinediones and insulin resistance
Potential Cardiovascular Effects Of Thiazolidinediones
Effect of Thiazolidinediones on Glycemia
The Truth about Lipid Effects of the Thiazolidinediones
No increase in HF risk or mortality with thiazolidinediones
Role of insulin resistance with the evidence from thiazolidinediones
Thiazolidinediones: Cardiovascular friend or foe
Impact of thiazolidinediones on cardiovascular disease risk factors
Breaking insulin resistance with thiazolidinediones
Drug Class Review: Thiazolidinediones
Thiazolidinediones may increase risk of heart failure
Thiazolidinediones increase fracture risk in both sexes
Thiazolidinediones and reduced bone density
Synthetic use of the ribosyl derivatives of 2, 4-and 2, 5-thiazolidinediones
Do thiazolidinediones increase the risk of cardiovascular events?
Thiazolidinediones–Emerging Evidence on Bone Formation
Thiazolidinediones Appear Safe for Diabetic Eyes
Metformin and thiazolidinediones
Insulin sensitizer drugs, thiazolidinediones: current state and prospect
The effect of thiazolidinediones on leucocytes in type II diabetic patients
Active pharmaceutical ingredient focus: Thiazolidinediones
Thiazolidinediones associated with increased fracture risk
Thiazolidinediones and cardiovascular outcomes in type 2 diabetes
Obesity, insulin resistance and the implication of thiazolidinediones
Thiazolidinediones in the treatment of type 2 diabetes
Precautions for use and contraindications of thiazolidinediones. A cardiologist opinion
Differences between Thiazolidinediones—Do the Lipid Effects Really Matter?
Rosiglitazone and the thiazolidinediones: A changing context
How about the effect of thiazolidinediones in diabetic nephropathy?
Microwave mediated synthesis and antifungal activity of some 5-benzylidene-2, 4-thiazolidinediones
Macular Edema and Thiazolidinediones—Reply
Thiazolidinediones And Type 2 Diabetes Mellitus Proven And Potential Benefits A Review
Thiazolidinediones in the Treatment of Type 2 Diabetes: A Clinician’s Perspective
Severe Cholestatic Hepatitis caused by Thiazolidinediones
Introduction: the role of the thiazolidinediones in the cardiovascular risk management of type 2 diabetes
Thiazolidinediones inhibit liver regeneration
Heart failure, diabetes and the thiazolidinediones: an unfolding story
REGIOSPECIFIC SYNTHESES OF α-GLUTAMYL PEPTIDES VIA 2, 5-THIAZOLIDINEDIONES. PART III.
Effect of thiazolidinediones on early retinopathy in rats with experimental diabetes
Are Thiazolidinediones Superior to Standard Therapy in the Treatment of Type 2 Diabetes?
THE EFFECTS OF THIAZOLIDINEDIONES ON BONE MINERAL DENSITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Thiazolidinediones Tied to Increased Fracture Risk
Combination of Metformin and Thiazolidinediones in Type 2 Diabetes Mellitus-A Review
Thiazolidinediones and Diabetic Macular Edema: Is There an Association?
The Molecular Mechanisms Underlying the Pro-Inflammatory Actions of Thiazolidinediones (TZDs) in Human Macrophages
Effects of Thiazolidinediones on Vascular Reactivity and Endothelial Dysfunction
Persistence rate with thiazolidinediones compared with other antihyperglycemic agents
Fluid retention with thiazolidinediones in diabetic heart failure
Oral thiazolidinediones increase feed intake and growth in sheep
Molecular characterization of insulin resistance in the adipose tissue and the effects of thiazolidinediones
Thiazolidinediones linked to bone loss in diabetic women
Post-Entry Market Analysis of New Drug for Diabetes: Penetration and Concentration of Thiazolidinediones (TZD)
Association Between Use of Thiazolidinediones and Costs of Heart Failure in Patients with Type 2 Diabetes.
Fracture Risk Spikes With Thiazolidinediones
Thiazolidinediones Improve Asthma Control In Diabetic Asthmatics
Thiazolidinediones combined with metformin in treatment of polycystic ovary syndrome: a systematic review
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA LIGANDS: THIAZOLIDINEDIONES: 502
Thiazolidinediones as selective algicides against harmful red-tide algae
Pharmaceuticals preparations containing thiazolidinediones for the treatment or prevention of IP-10 mediated diseases.
Oral bisphosphonates improve the bone mineral density in men with diabetes with or without thiazolidinediones
Effect of Thiazolidinediones Administration on Neurochemical Composition of MPG Neurons Related to Erection in OLETF Rat
Divergent Effects of Thiazolidinediones on Glucose Transport and Lipid Metabolism in Human Skeletal Muscle Cells
Thiazolidinediones (TZDs) downregulate Wnt/β-catenin signaling via multiple mechanisms in breast cancer cells
Meta-analysis of the Effect of Thiazolidinediones on Restenosis After Coronary Artery Stenting in Patients with or Without Diabetes Mellitus
Do Thiazolidinediones or Statins Suppress Post-Cardiothoracic Surgery Atrial Fibrillation in Diabetics?
Unraveling the effects of Thiazolidinediones and peroxisome proliferator-activated receptor gamma 1 on ovarian cancer
Thiazolidinediones Inhibit Vasoactive Agent-induced [Ca. sup. 2+] Mobilization and Cell Proliferation in Vascular Smooth Muscle Cells
Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function
Glucosamine Induced Insulin Resistance in 3T3L1 Adipocytes is Not Prevented by Thiazolidinediones
Do thiazolidinediones exert their insulin-sensitizing effect through the suppression of free Fatty acids?
The effects of glycemic control and thiazolidinediones on the risk of congestive heart failure among patients with type 2 diabetes
Thiazolidinediones decrease vascular endothelial growth factor (VEGF) production by human luteinized granulosa cells in vitro
Thiazolidinediones on Insulin Resistance and Insulin Secretion in Obese Diabetic OLETF Rats
The Anti-proliferative Effects of Thiazolidinediones and Non-steriodal Anti-inflammatory Drugs on Androgen-independent Prostate Cancer
Appropriateness of the use of Thiazolidinediones for the treatment of Type 2 Diabetes Mellitus at the Southern Arizona Veterans Affairs Hospital
The influence of thiazolidinediones on marbling in pigs: in vitro studies of muscle stromal-vascular cells from fetal and young pigs and in vivo studies of growing pigs
Insights on distinct pathways of thiazolidinediones (PPARc ligand)-promoted apoptosis in TRAIL-sensitive or-resistant malignant urothelial cells
Thiazolidinediones Attenuate Epithelial-Mesenchymal Transition And Pro-fibrotic Functions In Human Alveolar Epithelial Cells And Lung Fibroblasts
Type 2 diabetes mellitus: Which place for thiazolidinediones in the therapeutic strategy?
Effects of Thiazolidinediones on CETP/ApoB-100 Double Transgenic Mice Made Obese and Insulin Resistant by High Fat/High Carbohydrate Feeding
Synthesis and evaluation of antitumor activity of 5-[2-(3, 5-diaryl-4, 5-dihydro-pyrazol-1-yl)-2-oxo-ethylidene]-2, 4-thiazolidinediones
Govindarajan R, Ratnasinghe L, Simmons DL, Siegel ER, Midathada MV, Kim L, Kim PJ, Owens RJ, Lang NP: Thiazolidinediones and the risk of lung, prostate, and …
Thiazolidinediones (TZDs) Inhibit the Expression of Pro-Angiogenic ELR+ CXC Chemokines in Non-Small Cell Lung Cancer (NSCLC) Cells Via a PPAR-γ …
Thiazolidinediones (PPAR [Gamma] Agonists) but Not PPAR [Alpha] Agonists Rapidly Increase IRS-2 Gene Expression in 3T3-L1 Adipocytes
Thiazolidinediones Regulate Internal Ribosome Entry Site Dependent Translation of Insulin-Like Growth Factor-1 Receptor in Human Aortic Smooth Muscle Cells.
… , Prague, Czech Republic OBJECTIVE: Czech guidelines recommend additional therapy with sulfonylurea, insulin or thiazolidinediones (TZD) after met
Differential regulation of stearoyl-CoA desaturase expression and activity by thiazolidinediones, steroid hormones and fatty acid analogs using the mouse 3T3 …
… congenital partial lipodystrophy without lamin A/C and PPARγ mutations (Köbberling type or variety): A long-term follow-up regarding the efficacy of thiazolidinediones …
Thiazolidinediones (Pioglitazone) Blocks P. gingivalis-and F. nucleatum-, but not E. coli-Lipopolysaccharide (LPS)-induced interleukin-6 (IL-6) Production in …
The effect of thiazolidinediones on lipoprotein metabolism: A double blind randomised placebo controlled trial using stable isotopes to investigate the effect of …
Pathological Gambling Associated with Drug Therapy?: Blood Dyscrasias Associated with Thiazolidinediones: Olanzapine Can Cause Metabolic Problems if Used in …
Investigation of the reactivity and tautomerism of azolidines. 41. Reaction of 5-benzylidene-2, 4-thiazolidinediones with formaldehyde
P2-202 Thiazolidinediones are associated with regression of hepatosteatosis in people with type 2 diabetes: the Edinburgh type 2 diabetes study
1058 INSIGHTS ON PATHWAYS OF THIAZOLIDINEDIONES-PROMOTED APOPTOSIS IN “TUMOR NECROSIS FACTOR-RELATED APOPTOSIS INDUCING LIGAND …
Regulation of the Uncoupling Protein-3 Gene Expression by Thiazolidinediones
8 Effects of Thiazolidinediones
Thiazolidinediones: the forgotten diabetes medications
Thiazolidinediones as antidiabetic agents: A critical review
Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes
Thiazolidinediones
Thiazolidinediones and PPARγ agonists: time for a reassessment
Risk of fracture with thiazolidinediones: an updated meta-analysis of randomized clinical trials
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier
The current role of thiazolidinediones in diabetes management
Chemotherapy and chemoprevention by thiazolidinediones
Cancer risk for patients using thiazolidinediones for type 2 diabetes: A meta‐analysis
Thiazolidinediones and advanced liver fibrosis in nonalcoholic steatohepatitis: a meta-analysis
Thiazolidinediones and cancer: results of a meta-analysis of randomized clinical trials
Thiazolidinediones and associated risk of bladder cancer: a systematic review and meta‐analysis
Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus
Use of thiazolidinediones and the risk of bladder cancer among people with type 2 diabetes: a meta-analysis
Association between longer therapy with thiazolidinediones and risk of bladder cancer: a cohort study
Understanding contemporary use of thiazolidinediones: an analysis from the diabetes collaborative registry
Therapeutic actions of the thiazolidinediones in Alzheimer’s disease
Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus?
Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer
An update on the current and emerging use of Thiazolidinediones for type 2 diabetes
The effect of thiazolidinediones on bone mineral density and bone turnover: systematic review and meta-analysis
A new dawn for the use of thiazolidinediones in cancer therapy
Thiazolidinediones and edema: recent advances in the pathogenesis of thiazolidinediones-induced renal sodium retention
Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones: a systematic review
Thiazolidinediones and PPAR orchestra as antidiabetic agents: From past to present
Thiazolidinediones can prevent new onset atrial fibrillation in patients with non-insulin dependent diabetes
Thiazolidinediones and Parkinson disease: a cohort study
Sex and BMI alter the benefits and risks of sulfonylureas and thiazolidinediones in type 2 diabetes: a framework for evaluating stratification using routine clinical and …
Are thiazolidinediones a preferred drug treatment for type 2 diabetes?
An uncatalyzed aldol reaction of thiazolidinediones
Thiazolidinediones for nonalcoholic steatohepatitis: A meta-analysis of randomized clinical trials
Mitochondrial target of thiazolidinediones
A review on thiazolidinediones and bladder cancer in human studies
The journey of thiazolidinediones as modulators of PPARs for the management of diabetes: a current perspective
The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease
Risk of fracture with thiazolidinediones: an individual patient data meta-analysis
Effect of thiazolidinediones and insulin on cognitive outcomes in ACCORD-MIND
Thiazolidinediones are associated with a reduced risk of COPD exacerbations
Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism
Site-specific chemical modification of peptide and protein by thiazolidinediones
Thiazolidinediones under preclinical and early clinical development for the treatment of Parkinson’s disease
Targeting peroxisome proliferator-activated receptors using thiazolidinediones: strategy for design of novel antidiabetic drugs
Role of thiazolidinediones, insulin sensitizers, in non‐alcoholic fatty liver disease
Risk of stroke with thiazolidinediones: a ten-year nationwide population-based cohort study
Pharmacogenomics and pharmacogenetics of thiazolidinediones: role in diabetes and cardiovascular risk factors
The use of metformin, insulin, sulphonylureas, and thiazolidinediones and the risk of fracture: systematic review and meta‐analysis of observational studies
Risk of fracture with thiazolidinediones: disease or drugs?
Thiazolidinediones: an in–depth study of their synthesis and application to medicinal chemistry in the treatment of diabetes mellitus
Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice
Pleiotropic effects of thiazolidinediones: implications for the treatment of patients with type 2 diabetes mellitus
Thiazolidinediones for plaque psoriasis: a systematic review and meta-analysis
Synthesis, biological evaluation and molecular modeling studies of some novel thiazolidinediones with triazole ring
Novel potential artificial MRSA DNA intercalators: Synthesis and biological evaluation of berberine-derived thiazolidinediones
Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: a cohort study
Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes …
Effects of thiazolidinediones on polycystic ovary syndrome: a meta-analysis of randomized placebo-controlled trials
Variation in association between thiazolidinediones and heart failure across ethnic groups: retrospective analysis of large healthcare claims databases in six …
CYP2C8 and SLCO1B1 Variants and Therapeutic Response to Thiazolidinediones in Patients With Type 2 Diabetes
Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus
SP1-independent inhibition of FOXM1 by modified thiazolidinediones
Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women …
… thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones
Thiazolidinediones and risk of colorectal cancer in patients with diabetes mellitus: A meta-analysis
Efficacy and safety of thiazolidinediones in diabetes patients with renal impairment: a systematic review and meta-analysis
Thiazolidinediones attenuate lipolysis and ameliorate dexamethasone-induced insulin resistance
Insulin sensitizing and anti-inflammatory effects of thiazolidinediones are heightened in obese patients
Pyrrolidinediones reduce the toxicity of thiazolidinediones and modify their anti-diabetic and anti-cancer properties
Thiazolidinediones are associated with a decreased risk of atrial fibrillation compared with other antidiabetic treatment: a nationwide cohort study
The role of thiazolidinediones in hepatocellular carcinoma risk reduction: a population-based cohort study in Taiwan
Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists
Effects of three thiazolidinediones on metabolic regulation and cold-induced thermogenesis
The effects of thiazolidinediones on human bone marrow stromal cell differentiation in vitro and in thiazolidinedione-treated patients with type 2 diabetes
Association between colorectal cancer and thiazolidinediones administration in a case-control study
Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: In-silico studies, synthesis, and biological evaluation
Methylene thiazolidinediones as alkylation reagents in catalytic C–H functionalization: Rapid access to glitazones
Increased circulating adiponectin in response to thiazolidinediones: investigating the role of bone marrow adipose tissue
Use of thiazolidinediones and risk of osteoporotic fracture: disease or drugs?
Thiazolidinediones reduce the risk of hepatocellular carcinoma and hepatic events in diabetic patients with chronic hepatitis B
Thiazolidinediones improve flow-mediated dilation: a meta-analysis of randomized clinical trials
Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors …
Use of thiazolidinediones and the risk of colorectal cancer in patients with diabetes: a nationwide, population-based, case-control study
Deciphering the roles of thiazolidinediones and PPARγ in bladder cancer
Antidiabetic drugs for Alzheimer’s and Parkinson’s diseases: Repurposing insulin, metformin, and thiazolidinediones
Thiazolidinediones promote axonal growth through the activation of the JNK pathway
Capsaicin up-regulates pro-apoptotic activity of thiazolidinediones in glioblastoma cell line
Variable modulation by cytokines and thiazolidinediones of the prototype Th1 chemokine CXCL10 in anaplastic thyroid cancer
Pharmacological strategies for insulin sensitivity in obesity and cancer: thiazolidinediones and metformin
Effects of Thiazolidinediones on metabolism and cancer: Relative influence of PPARγ and IGF-1 signaling
Synthesis and structure–activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2
Thiazolidinediones abrogate cervical cancer growth
Effects of first-line diabetes therapy with biguanides, sulphonylurea and thiazolidinediones on the differentiation, proliferation and apoptosis of islet cell …
The direct effect of lobeglitazone, a new thiazolidinedione, on pancreatic beta cells: a comparison with other thiazolidinediones
Mechanistic insights into the augmented effect of bone marrow mesenchymal stem cells and thiazolidinediones in streptozotocin-nicotinamide induced …
Thiazolidinediones and Glucagon‐Like Peptide‐1 Receptor Agonists and the Risk of Nonalcoholic Fatty Liver Disease: A Cohort Study
Thiazolidinediones and risk of atrial fibrillation among patients with diabetes and coronary disease
Synthesis of Chiral Hydantoins and Thiazolidinediones via Iridium‐Catalyzed Asymmetric Hydrogenation
Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case–control study
PPARγ-Independent side effects of thiazolidinediones on mitochondrial redox state in rat isolated hearts
Design, synthesis, biological evaluation and molecular modelling studies of novel diaryl substituted pyrazolyl thiazolidinediones as potent pancreatic lipase inhibitors
The rise and fall of the thiazolidinediones: impact of clinical evidence publication and formulary change on the prescription incidence of thiazolidinediones
The role of thiazolidinediones in the amelioration of nonalcoholic fatty liver disease: a systematic review
Use of thiazolidinediones and risk of hip fracture in old people in a case–control study in Taiwan
Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors
Association of hepatocellular carcinoma with thiazolidinediones use: A population-based case-control study
Thiazolidinediones in the treatment of HIV/HAART-associated lipodystrophy syndrome
Design, synthesis, and molecular docking studies of thiazolidinediones as PPAR‐γ agonists and thymidylate synthase inhibitors
New thiazolidinediones affect endothelial cell activation and angiogenesis
Double-edged swords: diaryl pyrazoline thiazolidinediones synchronously targeting cancer epigenetics and angiogenesis
Use of thiazolidinediones and risk of bladder cancer: disease or drugs?
Synthesis and antihyperglycemic evaluation of new 2, 4-thiazolidinediones having biodynamic aryl sulfonylurea moieties
Benzylidene thiazolidinediones: synthesis, in vitro investigations of antiproliferative mechanisms and in vivo efficacy determination in combination with Imatinib
Thiazolidinediones lower the risk of pneumonia in patients with type 2 diabetes
In search of the neuroprotective mechanism of thiazolidinediones in Parkinson’s disease
Combination therapies with thiazolidinediones are associated with a lower risk of acute exacerbations in new-onset COPD patients with advanced diabetic …
Antifibrotic effects of the thiazolidinediones in eosinophilic esophagitis pathologic remodeling: a preclinical evaluation
Binding of thiazolidinediones to the endoplasmic reticulum protein nutrient-deprivation autophagy factor-1
Density Functional Study on the Cytochrome-Mediated S-Oxidation: Identification of Crucial Reactive Intermediate on the Metabolic Path of Thiazolidinediones
Thiazolidinediones play a positive role in the vascular endothelium and inhibit plaque progression in diabetic patients with coronary atherosclerosis: A …
Insulin sensitization therapy and the heart: focus on metformin and thiazolidinediones
PPARγ-independent activity of thiazolidinediones: a promising mechanism of action for new anticancer drugs?
Sensitivity and precision of adverse effects search filters in MEDLINE and EMBASE: a case study of fractures with thiazolidinediones
Lack of longitudinal association between thiazolidinediones and incidence and progression of diabetic eye disease: the ACCORD eye study
Novel N-phenyl–substituted thiazolidinediones protect neural cells against glutamate-and tBid-induced toxicity
Cardiovascular, ocular and bone adverse reactions associated with thiazolidinediones: a disproportionality analysis of the US FDA adverse event reporting system …
Thiazolidinediones as novel upstream therapy for atrial fibrillation in diabetic patients: a review of current evidence
A novel thiazolidinediones ATZD2 rescues memory deficits in a rat model of type 2 diabetes through antioxidant and antiinflammation
Thiazolidinediones were associated with higher risk of cardiovascular events in patients with type 2 diabetes and cirrhosis
AMP-activated protein kinase mediates the antiplatelet effects of the thiazolidinediones rosiglitazone and pioglitazone
Thiazolidinediones (TZDs)
Metabonomic profiling revealed an alteration in purine nucleotide metabolism associated with cardiac hypertrophy in rats treated with thiazolidinediones
Effects of safety warnings and risk management plan for Thiazolidinediones in Taiwan
Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones
Thiazolidinediones improve hepatic fibrosis in rats with non‐alcoholic steatohepatitis by activating the adenosine monophosphate‐activated protein kinase signalling …
Statins, fibrates, thiazolidinediones and resveratrol as adjunctive therapies in sepsis: could mitochondria be a common target?
Structure–activity analysis of harmful algae inhibition by congeneric compounds: case studies of fatty acids and thiazolidinediones
Reversible inhibition of vasoconstriction by thiazolidinediones related to PI3K/Akt inhibition in vascular smooth muscle cells
GIPR expression is induced by thiazolidinediones in a PPARγ-independent manner and repressed by obesogenic stimuli
How Did Multiple FDA actions affect the utilization and reimbursed costs of thiazolidinediones in US medicaid?
Association of the Pro12Ala gene polymorphism with treatment response to thiazolidinediones in patients with type 2 diabetes: a meta-analysis
Thiazolidinediones protect mouse pancreatic β-cells directly from cytokine-induced cytotoxicity through PPARγ-dependent mechanisms
The medicinal perspective of 2, 4‐thiazolidinediones based ligands as antimicrobial, antitumor and antidiabetic agents: A review
The impact of thiazolidinediones on the risk for prostate cancer in patients with type 2 diabetes mellitus: a review and meta-analysis
Antitumor effects of energy restriction-mimetic agents: thiazolidinediones
Multi-target weapons: diaryl-pyrazoline thiazolidinediones simultaneously targeting VEGFR-2 and HDAC cancer hallmarks
Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of …
Biphenyl tetrazole-thiazolidinediones as novel bacterial peptide deformylase inhibitors: synthesis, biological evaluations and molecular docking study
Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver
Upregulation of hepatic LRP1 by rosiglitazone: a possible novel mechanism of the beneficial effect of thiazolidinediones on atherogenic dyslipidemia
Discovery of rhodanine and thiazolidinediones as novel scaffolds for EGFR inhibition: design, synthesis, analysis and CoMSIA studies
Synthesis, In‐Vitro Evaluation and Molecular Docking Study of N‐Substituted Thiazolidinediones as α‐Glucosidase Inhibitors
Comparing the effects of insulin glargine and thiazolidinediones on plasma lipids in type 2 diabetes: a patient‐level pooled analysis
Association of hemoglobin A1c levels with use of sulfonylureas, dipeptidyl peptidase 4 inhibitors, and thiazolidinediones in patients with type 2 diabetes treated with …
Thiazolidinediones and risk of long-term dialysis in diabetic patients with advanced chronic kidney disease: a nationwide cohort study
Therapeutic journey of 2, 4-thiazolidinediones as a versatile scaffold: An insight into structure activity relationship
Differential effects of thiazolidinediones and dipeptidyl peptidase-4 inhibitors on insulin resistance and β-cell function in type 2 diabetes mellitus: a propensity …
A new series of 2, 4-thiazolidinediones endowed with potent aldose reductase inhibitory activity
Synthesis, characterization and biological evaluation of some novel 2, 4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents
Synthesis of New N‐Substituted 5‐Arylidene‐2,4‐thiazolidinediones as Anti‐Inflammatory and Antimicrobial Agents
Thiazolidinediones, alpha-glucosidase inhibitors, meglitinides, sulfonylureas, and hepatocellular carcinoma risk: a meta-analysis
Correlation between PPARG Pro12Ala Polymorphism and Therapeutic Responses to Thiazolidinediones in Patients with Type 2 Diabetes: A Meta-Analysis
PPARγ-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development
Efficacy and cardiovascular safety of Thiazolidinediones
2, 4-Thiazolidinediones as PTP 1B Inhibitors: A Mini Review (2012-2018)
Molecular remodeling of the insulin receptor pathway by thiazolidinediones in type 2 diabetes mellitus: A brief review
Thiazolidinediones (TZDs) affect osteoblast viability and biomarkers independently of the TZD effects on aromatase
Apolipoprotein E gene polymorphisms affect the efficacy of thiazolidinediones for Alzheimer’s disease: a systematic review and meta-analysis
Current advances in the biochemical and physiological aspects of the treatment of type 2 diabetes mellitus with thiazolidinediones
… of PPARγ2 in the Heart Determines Differences in Hypertrophic Cardiomyopathy After Treatment With Different Thiazolidinediones in a Mouse Model of …
A solvent-free protocol for the green synthesis of 5-arylidene-2, 4-thiazolidinediones using ethylenediamine diacetate as catalyst
Thiazolidinediones regulate the level of ABC transporters expression on lung cancer cells
Recent pharmacological developments on rhodanines and 2, 4-thiazolidinediones
Impact of thiazolidinediones on macular thickness and volume in diabetic eyes
Antimicrobial activity of thiazolyl benzenesulfonamide-condensed 2, 4-thiazolidinediones derivatives
Synthesis and structure-activity relationship studies of 2, 4-thiazolidinediones and analogous heterocycles as inhibitors of dihydrodipicolinate synthase
Clinical outcomes and health care costs combining metformin with sitagliptin or sulphonylureas or thiazolidinediones in uncontrolled type 2 diabetes patients
Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies
Sodium-glucose cotransporter protein-2 inhibitors and glucagon-like peptide-1 receptor agonists versus thiazolidinediones for non-alcoholic fatty liver disease: A …
Long-term therapy with thiazolidinediones and the risk of bladder cancer: A cohort study.
Decreased risk of liver cancer with thiazolidinediones therapy in patients with type 2 diabetes: Results from a meta-analysis
Design, synthesis and biological evaluation of novel 5-(imidazolyl-methyl) thiazolidinediones as antidiabetic agents
Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2,4-thiazolidinediones
Benzisoxazole containing thiazolidinediones as peroxisome proliferator activated receptor-γ agonists: design, molecular docking, synthesis & antidiabetic …
Incretins and thiazolidinediones in glucose homeostasis and cancer: Role of common polymorphisms
An insight into the synthesis and SAR of 2, 4-thiazolidinediones (2, 4-TZD) as multifunctional scaffold: a review
Synthesis of some new 2-amino-6-thiocyanato benzothiazole derivatives bearing 2, 4-thiazolidinediones and screening of their in vitro antimicrobial, antitubercular …
Different effects of thiazolidinediones on in-stent restenosis and target lesion revascularization after PCI: a meta-analysis of randomized controlled trials
Keratinocyte growth factor and thiazolidinediones and linolenic acid differentiate characterized mammary fat pad adipose stem cells isolated from prepubertal Korean …
Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 …
Treatment with thiazolidinediones
Polycystic ovarian syndrome: metformin or thiazolidinediones for cardiovascular risk reduction?
5-Arylidene (chromenyl-methylene)-thiazolidinediones: potential new agents against mutant oncoproteins K-Ras, N-Ras and B-Raf in colorectal cancer and …
Comparison of the Effects of Metformin and Thiazolidinediones on Bone Metabolism: A Systematic Review and Meta-Analysis
Additive effects of omega-3 fatty acids and thiazolidinediones in mice fed a high-fat diet: triacylglycerol/fatty acid cycling in adipose tissue
Association of thiazolidinediones with gastric cancer in type 2 diabetes mellitus: a population-based case–control study
Thiazolidinediones downregulate PPARγ expression via induction of aP2 during mouse 3T3-L1 preadipocyte differentiation
Novel 2, 4-thiazolidinediones: Synthesis, in vitro cytotoxic activity, and mechanistic investigation
The effect of exposure to thiazolidinediones on the development of head-and-neck cancer in patients with diabetes mellitus
Synthesis, biological evaluation and molecular docking studies of novel 3, 5-disubstituted 2, 4-thiazolidinediones derivatives
Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones
Thiazolidinediones in the treatment of type 2 diabetesmellitus
… activating receptor gamma–independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinediones
Comparison of sodium-glucose cotransporter-2 inhibitors and thiazolidinediones for management of non-alcoholic fatty liver disease: A systematic review and meta …
Synthesis and in vitro cytotoxicity evaluation of phenanthrene linked 2, 4-thiazolidinediones as potential anticancer agents
Hydroxyl ammonium ionic liquid-catalyzed simple and efficient synthesis of 5-arylidene-2, 4-thiazolidinediones under solvent-free conditions
Synthesis of 5-Alkylidene-2, 4-thiazolidinediones and Rhodanines Promoted by Propylamino-functionalized Nano-structured SBA-15
Thiazolidinediones and macular edema: comment on “Association between thiazolidinedione treatment and risk of macular edema among patients with type 2 …
Experimental and theoretical study of substituent effect on 13C NMR chemical shifts of 5-arylidene-2, 4-thiazolidinediones
Energy restriction mimetic agents to target cancer cells: comparison between 2-deoxyglucose and thiazolidinediones
Thiazolidinediones Cause Cardiotoxicity via PPARγ-Independent Mechanism
Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC)
Thiazolidinediones as antidiabetic agents-A Review
Synthesis of newer 5-benzylidene-2, 4-thiazolidinediones as potential antimicrobials
Clinical effect of thiazolidinediones in subjects with disorders of carbohydrate metabolism in case of polymorphism rs1801282
Sonochemistry: A good, fast and clean method to promote the synthesis of 5-arylidene-2, 4-thiazolidinediones
Newer second-line glucose-lowering drugs versus thiazolidinediones on cirrhosis risk among older US adult patients with type 2 diabetes
Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon …
The impact of water molecules on binding affinity of the anti-diabetic thiazolidinediones for catalase: Kinetic and mechanistic approaches
Nitro-oleic acid protects mice from diet-induced hepatic steatosis and insulin resistance without the adverse side effects of thiazolidinediones
Effect of thiazolidinediones on adipocytokines and lipid profile in insulin resistant sprague dawley rats
Intensification with dipeptidyl peptidase-4 inhibitor, insulin, or thiazolidinediones and risks of all-cause mortality, cardiovascular diseases, and severe …
… , Hypoglycaemic, Hypolipidemic and PPAR γ Agonist Activities of 5‐(2‐Alkyl/aryl‐6‐Arylimidazo [2, 1‐b][1, 3, 4] thiadiazol‐5‐yl) methylene‐1, 3‐Thiazolidinediones
Substituent and solvent effects on intramolecular charge transfer of 5-arylidene-2, 4-thiazolidinediones
Design and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors
Development of new 5-(chromene-3-yl) methylene-2, 4-thiazolidinediones as antimicrobial agents
Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
Brown Adipose Tissue PPARγ Is Required for the Insulin-Sensitizing Action of Thiazolidinediones
Comparative efficacy of thiazolidinediones and metformin for polycystic ovary syndrome
Synthesis of Bioactive Thioxoimidazolidinones, Oxazolidinones, Thioxothiazolidinones, Thiazolidinediones
Possible Protective Effects of Thiazolidinediones Antidiabetic Drugs in Colorectal Cancer
Implications of removing rosiglitazone’s black box warning and restricted access program on the uptake of thiazolidinediones and dipeptidyl peptidase-4 inhibitors …
Thiazolidinediones Inhibit Mouse Osteoblastic MC3T3-E1 Cell Proliferation in Part Through the Wnt Signaling Pathway
Insilico Activity Prediction of Thiazolidinediones Derivatives
Effects of thiazolidinediones on cardiovascular events in patients with type 2 diabetes mellitus after drug-eluting stent implantation: a retrospective cohort study using …
Solid acid TS-1 catalyst: an efficient catalyst in Knoevenagel condensation for the synthesis of 5-arylidene-2, 4-thiazolidinediones/Rhodanines in aqueous medium
Simultaneous determination of antidiabetic thiazolidinediones using flow through voltammetric sensor
Glitazones (thiazolidinediones)
A review on the clinical safety of thiazolidinediones
DPP4i, thiazolidinediones, or insulin and risks of cancer in patients with type 2 diabetes mellitus on metformin–sulfonylurea dual therapy with inadequate …
Preparation of Mg-doped Ce-Zr solid catalysts and their catalytic potency for the synthesis of 5-arylidene-2, 4-thiazolidinediones via Knoevenagel condensation
Effect of Thiazolidinediones on Renal Outcomes in Diabetic Patients with Microalbuminuria or Macroalbuminuria-A Systematic Review and Meta-analysis
Antioxidant activities of some new chromonyl-2, 4-thiazolidinediones and chromonyl-2, 4-imidazolidinediones having chromone cores
Solvent and substituent effect on intramolecular charge transfer in 5-arylidene-3-substituted-2, 4-thiazolidinediones: Experimental and theoretical study
Insertion of thiazolidinediones into carbon nanotube
Thiazolidine, thiazolidinediones, TZD
Phosphoryl Chloride Mediated Synthesis of 5-Arylidene-2, 4-Thiazolidinediones Derivatives via Aromatic Bisulfite Adducts
Estimation of plasma glucose and creatinine level in alloxan-induced diabetic wistar rats treated with metformin and thiazolidinediones
Is thiazolidinediones use a factor in delaying the need for insulin therapy in type 2 patients with diabetes? A population-based cohort study
Correlation between activation of PPARγ and resistin downregulation in a mouse adipocyte cell line by a series of thiazolidinediones
ZnO nanobelts: an efficient catalyst for synthesis of 5-arylidine-2, 4-thiazolidinediones and 5-arylidine-Rhodanines
Effects of rosiglitazone on the cardiovascular profile in postmenopausal women without diabetes mellitus: interplay of thiazolidinediones and hormone therapy
Cushingoid lipodystrophy can be prevented by thiazolidinediones
… of anti-diabetic therapy on overweight/obesity and dyslipidemia: traditional hypoglycemic agents (metformin, sulfonylureas, thiazolidinediones) versus glucagon-like …
Unexpected regio-and stereoselective [4+ 3] cycloaddition reaction of azomethine ylides with benzylidene thiazolidinediones: synthesis of pharmacologically active …
Synthesis and pharmacological evaluation of 2, 4-thiazolidinediones as antidiabetic agents
Thiazolidinediones versus metformin on improving abnormal liver enzymes in patients with type 2 diabetes mellitus: A meta-analysis
Thiazolidinediones and reduced risk of incident bacterial abscess in adults with type 2 diabetes: A population‐based cohort study
Thiazolidinediones: A class of pharmacologically important molecules.
Effect of hyperglycemia and thiazolidinediones on cardiac angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) in db/db diabetic mice.
Chemistry and Applications of Functionalized 2, 4‐Thiazolidinediones
Molecular docking studies of novel arylidene-2, 4-thiazolidinediones as potential aldose reductase inhibitors
Differential characterization of myogenic satellite cells with linolenic and retinoic acid in the presence of thiazolidinediones from prepubertal Korean black …
Physiologically Based Pharmacokinetic Modeling and Simulation of Thiazolidinediones in Patients with Hepatic Impairment
Chemometric study of retention indices of some thiazolidinediones derivatives in two low polarity stationary phases
Virtual Screening, Docking, Synthesis and Bioactivity Evaluation of Thiazolidinediones as Potential PPARγ Partial Agonists for Preparation of Antidiabetic Agents
Ability of two new thiazolidinediones to downregulate proinflammatory cytokines in peripheral blood mononuclear cells from children with asthma
Role of Galactose, Thiazolidinediones, and NEET proteins in Mitochondrial physiology and therapeutic development.
Deciphering the Roles of Thiazolidinediones and PPAR in Bladder Cancer
Design, Synthesis and Antidiabetic Evaluation of New Cyanoquinoloxy Benzylidenyl 2, 4-Thiazolidinediones.
Assorted applications of N-substituted-2, 4-thiazolidinediones in various pathological conditions
The effect of Thiazolidinediones on the vascular endothelium and plaque in diabetic patients with coronary atherosclerosis: a meta-analysis
Synthesis and evaluating anti-inflammatory, antibacterial activity of substituted benzylidene thiazolidinediones
… : efficient, inexpensive and reusable catalysts for the synthesis of pyrazole derivatives with 2-iminothiazolidin-4-one and 2, 4-thiazolidinediones under solvent-free …
Synthesis of novel 1, 2, 3-triazoles bearing 2, 4 thiazolidinediones conjugates and their biological evaluation
Adiponectin versus thiazolidinediones and angiotensin receptor blockers
Thiazolidinediones and Rheumatoid Arthritis: A Retrospective Cohort Study
Current drug information: Thiazolidinediones associated with increased risk of bladder cancer among adults with type 2 diabetes
Heterocyclyl linked phenyl containing Thiazolidinediones and its Cyclic analogs as potential novel Antidiabetic agents
Clinical Management of Nonalcoholic Steatohepatitis (NASH) With the Use of Thiazolidinediones and the Additive Effect of Thiazolidinediones and a GLP-1 …
Correction: Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the General Practice Research Database and secondary care data
The Effect of Thiazolidinediones and SGLT-2 Inhibitors on Minerals, VIT. D3, Blood Glucose and Weight Gain in Wistar Rats Induced with Type 2 Diabetes
Investigation of substituted thiazolidinediones as corrosion inhibitors on different metals in acidic media
The Spectrum of Thiazolidinediones against Respiratory Tract Pathogenic Bacteria: An In Vitro and In Silico Approach
… range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation, chemotherapy, thiazolidinediones). However, to advance …
Hypoglycemic and Hypolipidemic Swords: Synthesis and In-vivo Biological Assessment of 5-benzylidene-2, 4-thiazolidinediones
… of anti-diabetic drugs on risk of fracture in type 2 diabetes mellitus patients: a network meta-analytic synthesis of randomized controlled trials of thiazolidinediones
The clinical summary of thiazolidinediones in the treatment of T2DM.
Green Synthesis of 5-Arylidene-2, 4-Thiazolidinediones Over FeAlPO-5 Catalysts
Effects of Metformin compared to Thiazolidinediones on vascular endothelial function in Polycystic Ovary syndrome: A systematic review
ROLES OF THIAZOLIDINEDIONES IN TYPE 2 DIABETES MELLITUS TREATMENT AND WEIGHT GAIN
The effect of diabetes mellitus, insulin, and thiazolidinediones on bone histomorphometry in streptozotocin-induced diabetic postmenopausal wistar rats
The Use of Thiazolidinediones in Type 2 Diabetic Patients
Increasing endogenous PPARγ ligands improves insulin sensitivity and protects against diet-induced obesity without side effects of thiazolidinediones
Are thiazolidinediones effective in the treatment of nonalcoholic steatohepatitis (NASH)?
Use of thiazolidinediones and risk of bladder cancer: disease or drugs?
Beneficial Effects of Inhibition of the Mitochondrial Pyruvate Carrier and the Mechanism of Action of Thiazolidinediones
Exploring off‐target binding of thiazolidinediones and a novel mechanism for restoring insulin sensitivity (854.2)
Effects of Thiazolidinediones on In-Stent Restenosis: A Review of IVUS Studies
Thiazolidinediones as selective algicides against harmful algae
Effects of thiazolidinediones on vascular endothelial function in patients with type 2 diabetes mellitus
Development of oedema is associated with an improved glycaemic response in patients initiating thiazolidinediones: a MASTERMIND study
A Retrospective Evaluation of the use of Thiazolidinediones in Patients with Diabetes Mellitus in a Private Hospital in Ras Al Khaimah.
Comparative efficacy of thiazolidinediones and metformin for polycystic ovary syndrome
Modulation of visfatin levels by thiazolidinediones in insulin resistant sprague dawley rats
Substituent effects on chromatographic retention data of 5-arylidene-2, 4-thiazolidinediones in qsar methodology
Modulation of visfatin levels by thiazolidinediones in insulin resistant sprague dawley rats
Effect of thiazolidinediones on insulin resistance and reduced-fat liver
Effect of Thiazolidinediones (Glitazones) groups on Glycemic control and Lipid profile: A Meta-analysis of Randomized Control Trials
Thiazolidinediones as potential therapeutic agents in atopic eczema
Thiazolidinediones Promote Axonal Growth through the Activation of the JNK
In Silico Study on the Interaction of Thiazolidinediones and β-Lactoglobulin by Molecular Dynamics and Docking Approach
… of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation, chemotherapy, thiazolidinediones). However, to advance …
Effect of thiazolidinediones on dislipidemia in patients with metabolic syndrome depending on the gene PPAR-gamma rs1801282 polymorphism
Influence of esomeprazole on the pharmacodynamic activity of thiazolidinediones (pioglitazone and rosiglitazone) in animal models
Controlled clinical trial with the combination therapy with metformin, thiazolidinediones, glucagon-like peptide 1 analog in patients with type 2 diabetes and metabolic …
Clinical Outcomes and Health Care Costs Evaluation of Sulfonamides and Thiazolidinediones Compared with Dipeptidyl Peptidase 4 Inhibitors for the Treatment of …
Triple Therapy with Dpp4 Inhibitor, Insulin, or Thiazolidinediones and Risks of Cardiovascular Diseases and All-Cause Mortality in Patients with Failed Metformin-SU …
Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies
Thiazolidinediones’ Insulin-Sensitizing Properties Depend on Adiponectin-Mediated Reductions in Certain Ceramide Species
… between (UCP1-independent) antidiabetic effects (MSDC-0602) and adipogenic and browning-inducing effects (MSDC-0160) of classical thiazolidinediones …
Thiazolidinediones augment anticancer effects of gemcitabine on human pancreatic cancer cells through PPARδ activation
Effect of thiazolidinediones: PPAR [gamma] agonists on hormones secretion by cells of human adrenocortical cancer in vitro
Differential Effects of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors on Insulin Resistance and b-Cell Function in Type 2 Diabetes Mellitus: A …
Efficacy and Safety of Once-Weekly Semaglutide vs. Sitagliptin as Add-on to Metformin and/or Thiazolidinediones after 56 Weeks in Subjects with Type 2 Diabetes …
Stratification using gender and body mass index (BMI) can predict side-effect risk in people with Type 2 diabetes initiating thiazolidinediones but not sulphonylureas: a …
OR14-05 Hepatocyte Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Offsets the Anti-Steatogenic Effects of Thiazolidinediones in Obese Male Mice
In the article “Incidence of Cardiovascular Events in Which 2 Thiazolidinediones Are Used as Add-on Treatments for Type 2 Diabetes Mellitus in a Taiwanese …
Synthesis of new 5-(chromene-3-yl) methylene-2, 4-thiazolidinediones
Synthesis and In-Vitro Anticancer Evaluation of Novel 5-Substituted Thiazolidinediones
Novel 2, 4-thiazolidinediones: synthesis, in vitro cytotoxic activity, and mechanistic investigation
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