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Rottlerin
Rottlerin
… (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn
… Receptor Crosstalk: The IL-4-induced Alternate Pathway for BCR Signaling Operates in Parallel with the Classical Pathway, Is Sensitive to Rottlerin, and Depends on …
303 ENHANCED THERAPY SUCCESS OF RENAL CELL CARCINOMA USING TYROSINE KINASE INHIBITORS COMBINED WITH ROTTLERIN
64PEffects of Rottlerin and genistein through EF2K on proliferation, invasion and cell cycle/death in neuroblastoma cells
A polyphenolic compound Rottlerin demonstrates significant in vitro cytotoxicity against human cancer cell lines: isolation and characterization from the fruits of …
AB161. Rottlerin-induced autophagy leads to the apoptosis in bladder cancer cells
Abstract LB-011: PAK1 inhibitor FRAX1036 sensitizes ovarian cancer cells with amplified 11q13 to cytotoxic effect of rottlerin
Activation of BKCa Channels With Rottlerin Greatly Improves Cardiac Functional Improvement Following Surgical Ischemia Associated With Cardioplegic Arrest.
Alternative pathways of cancer cell death by rottlerin: apoptosis versus autophagy
Anti-allergic actions of Rottlerin from Mallotus philippinensis in experimental mast cell-mediated anaphylactic models
Antiproliferative effect of Rottlerin on SK-MEL-28 melanoma cells
Arsenite-Stimulated Glucose Uptake in 3T3-L1 Adipocytes Is Sensitive to Inhibition by Rottlerin and Ro-31-8220
Biosynthesis of promatrix metalloproteinase-9/
chondroitin sulphate proteoglycan heteromer involves a Rottlerin-sensitive pathway
Coadministration of sorafenib with Rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells
Critical appraisal of the MTT assay in the presence of Rottlerin and uncouplers
Design, synthesis and functional characterization of Rottlerin analogs
Determination of rottlerin, a natural protein kinases C inhibitor, in pancreatic cancer cells and mouse xenografts by RP-HPLC method
Development and validation of a RP-HPLC method for quantification of Rottlerin in Kamala (Mallotus philppinensis).
Development and validation of a RP-HPLC method for the simultaneous determination of Embelin, Rottlerin and Ellagic acid in Vidangadi churna
Down-regulation of caspase-2 by Rottlerin via protein kinase C-δ–independent pathway
Down-regulation of Caspase-2 by Rottlerin via Protein Kinase CD–Independent Pathway
Effect of rottlerin, a PKC-δ inhibitor, on TLR-4-dependent activation of murine microglia
Effects of Rottlerin on in vitro proliferation of and expressions of interleukin-17C, CCL20 and nuclear factor-κB in a human keratinocyte cell line HaCaT
Effects of Rottlerin on silica-exacerbated systemic autoimmune disease in New Zealand mixed mice
Effects of rottlerin, an inhibitor of calmodulin-dependent protein kinase III, on cellular proliferation, viability, and cell cycle distribution in malignant glioma cells.
Effects of Rottlerin, an Inhibitor of Calmodulin-dependent Protein Kinase Ill, on Cellular Proliferation, Viability, and Cell Cycle Distribution in Malignant Glioma …
Efficient synthesis of Rottlerin and its two subunits
Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor Rottlerin and relative insensitivity towards staurosporine
Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor Rottlerin and relative insensitivity towards staurosporine
Expression of protein kinase c (pkc) isoforms and the effect of selective pkc-s inhibition by Rottlerin on the induction of apoptosis in acute promyelocytic leukemia
Improved synergistic anticancer efficacy of quercetin in combination with PI-103, rottlerin, and G0 6983 against MCF-7 and RAW 264.7 cells
Inhibition of amyloid fibril formation and disassembly of pre-formed fibrils by natural polyphenol rottlerin
Inhibition of eukaryotic elongation factor-2 kinase mediates Rottlerin induced effects in apoptosis and cell proliferation inhibition in human pancreatic cancer cells.
Inhibition of Notch-1 pathway is involved in rottlerin-induced tumor suppressive function in nasopharyngeal carcinoma cells
Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing
Integrated in Silico Docking and MOMA Simulation Methods Reveal Rottlerin as a Potent Janus kinase 2 (JAK2) Inhibitor
Integrin signaling and cell spreading alterations by Rottlerin treatment of chick limb bud mesenchymal cells
Kinase inhibitors tyrphostin 9 and Rottlerin block early steps of rabies virus cycle
Links between L-glutamate transporters, Na+/K+-ATPase and cytoskeleton in astrocytes: evidence following inhibition with rottlerin
Mechanisms of apoptosis-induction by rottlerin: therapeutic implications for B-CLL
Mechanisms of Rottlerin-mediated inhibition of chlamydial growth
Mo1954 Rottlerin Promotes Apoptosis and Autophagy in Pancreatic Stellate Cells via AMPK Activation
Multi-Functional Role of Rottlerin, PKC-Delta Inhibitor, in Immune Cells and Cancer Cells
Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells
Neuroprotective effect of protein kinase Cδ inhibitor Rottlerin in cell culture and animal models of Parkinson’s disease
Non-conventional Rottlerin anticancer properties
NOX, RAS and PKC-Δ as Key Players in Kidney Diseases: A Possible Role of Rottlerin
Phosphorylation-independent mTORC1 inhibition by the autophagy inducer Rottlerin
Possible mechanism of Rottlerin induced modulation of ischemia reperfusion injury in isolated rat hearts
Potent stimulation of large‐conductance Ca2+‐activated K+ channels by rottlerin, an inhibitor of protein kinase C‐δ, in pituitary tumor (GH3) cells and in cortical …
Potential in for PKC inhibitor Rottlerin in murine experimental model of asthma
Potentiation of tumor necrosis factor-α-induced cell death by Rottlerin through a cytochrome-c-independent pathway
Prevention of TNF-induced necrotic cell death by Rottlerin through a Nox1 NADPH oxidase
Protection of human colon epithelial cells against deoxycholate by rottlerin
Protein kinase C-δ inhibitor, Rottlerin inhibits growth and survival of mycobacteria exclusively through Shikimate kinase
Protein kinase C‐delta is commonly expressed in multiple myeloma cells and its downregulation by Rottlerin causes apoptosis
Receptor Activator of Nuclear Factor-icB Is Induced by a Rottlerin-sensitive and p38 MAP Kinase-dependent Pathway during Monocyte Differentiation.
Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation
Research Article Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy
Research Article Rottlerin Inhibits ROS Formation and Prevents NFκB Activation in MCF-7 and HT-29 Cells
Reversal of the negative effects of TGFβ1 on human articular chondrocytes by PKCδ inhibition with rottlerin
Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues
Rottlerin and cancer: novel evidence and mechanisms
Rottlerin and curcumin: a comparative analysis
Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies
Rottlerin causes pulmonary edema in vivo: a possible role
Rottlerin causes pulmonary edema in vivo: a possible role for PKCδ
Rottlerin Derivatives and Other Compounds from Mallotus philippinensis Fruits and Their Potential Antimycobactrial Activity
Rottlerin diminished the lipid accumulation in 3T3-L1 cell line and enhanced the uncoupling of oxidative phosphorylation in D16 cell line via LRP6 mediated pathway
Rottlerin dissolves pre-formed protein amyloid: A study on hen egg white lysozyme
Rottlerin enhances IL-1β-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells
Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells
Rottlerin exhibits anti-cancer effect through inactivation of S phase kinase-associated protein 2 in pancreatic cancer cells
Rottlerin Exhibits Antiangiogenic Effects In vitro
Rottlerin exhibits antitumor activity via down-regulation of TAZ in non-small cell lung cancer
Rottlerin greatly improves cardiac functional recovery following ischemic cardioplegic arrest (CP) in wild-type but not BKCa channel knockout mice
Rottlerin impairs the formation and maintenance of psychostimulant-supported memory
Rottlerin Increases Cardiac Contractile Performance and Coronary Perfusion Through BKCa++ Channel Activation After Cold Cardioplegic Arrest in Isolated Hearts
Rottlerin induce early autophagy and late apoptosis via PKC-delta independent pathway.
Rottlerin induced autophagy by targeting multiple sites that leads to the apoptosis in cancer stem cells
Rottlerin induces a transformed phenotype in human keratinocytes
Rottlerin induces apoptosis in pancreatic cancer cells through the interaction with Bcl-2 family proteins
Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism
Rottlerin induces apoptosis of human blood eosinophils: A possible role for PKC-[delta] in mediating eosinophil survival
Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC δ-independent mechanism in human malignant tumor cells
Rottlerin Induces Apoptosis via Death Receptor5 (DR5) Up-Regulation through CHOP-Dependent and PKC d-Independent Mechanism in Human Malignant Tumor …
Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of …
Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
Rottlerin induces calcium influx and protein degradation in cultured lenses independent of effects on protein kinase Cδ
Rottlerin induces cyclooxygenase-2 upregulation through an ATF4 and reactive oxygen species-independent pathway in HEI-OC1 cells
Rottlerin induces ER stress-mediated cell death in pancreatic stellate cells
Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC δ-independent pathway in human colon …
Rottlerin Induces Heme Oxygenase-1 through ROS generation, p38 and Akt Phosphorylation and Nrf2/ARE Activation in Human Colon Cancer HT29 Cells
Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-δ-independent pathway in human colon cancer cells
Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells
Rottlerin inhibitis agonist-stimulated tyrosine phosphorylation (TyrP), MAPK activation, and amylase secretion by depleting intracellular ATP in rat …
Rottlerin Inhibits (Na+, K+)-ATPase Activity in Brain Tissue and Alters d-Aspartate Dependent Redistribution of Glutamate Transporter GLAST in Cultured Astrocytes
Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-Aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes
Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cells
Rottlerin inhibits cell growth and invasion via down-regulation of EZH2 in prostate cancer
Rottlerin inhibits cell growth, induces apoptosis and cell cycle arrest, and inhibits cell invasion in human hepatocellular carcinoma
Rottlerin inhibits chlamydial intracellular growth and blocks chlamydial acquisition of sphingolipids from host cells
Rottlerin inhibits human T cell responses
Rottlerin inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes by uncoupling mitochondrial oxidative phosphorylation
Rottlerin inhibits Lonicera japonica-induced photokilling in human lung cancer cells through cytoskeleton-related signaling cascade
Rottlerin inhibits migration of follicular thyroid carcinoma cells by PKCδ‐independent destabilization of the focal adhesion complex
Rottlerin inhibits migration of thyroid follicular carcinoma through destablization of the focal adhesion complex
Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes
Rottlerin inhibits P2X7 receptor‐stimulated phospholipase D activity in chronic lymphocytic leukaemia B‐lymphocytes
Rottlerin Inhibits ROS Formation and Prevents NF 𝜅 B Activation in MCF-7 and HT-29 Cells
Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-δ …
Rottlerin inhibits the nuclear factor κB/Cyclin-D1 cascade in MCF-7 breast cancer cells
Rottlerin inhibits tonicity-dependent expression and action of TonEBP in a PKCδ-independent fashion
Rottlerin is a mitochondrial uncoupler that decreases cellular ATP
Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cδ tyrosine phosphorylation
Rottlerin is a pan phosphodiesterase inhibitor and can induce neurodifferentiation in IMR-32 human neuroblastoma cells
Rottlerin Mediated Modulation of Tonicity-Responsive Enhancer Binding Protein (TonEBP) In Wistar Rats
Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I …
Rottlerin promotes apoptosis and autophagy in pancreatic stellate cells via AMPK activation
Rottlerin promotes autophagy and apoptosis in gastric cancer cell lines
Rottlerin protected dopaminergic cell line from cytotoxicity of 6-hydroxydopamine by inhibiting PKCδ phosphorylation
Rottlerin Reduces cAMP/CREB-Mediated Melanogenesis via Regulation of Autophagy
Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria …
Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
Rottlerin stimulates apoptosis in pancreatic cancer
Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family
Rottlerin stimulates apoptosis in pancreatic cancer through inhibition of Bcl-xL
Rottlerin stimulates metallothionein gene expression but inhibits metal transport in Chinese hamster ovary cells
Rottlerin Suppresses Airway Hyperreactivity And Inflammation In Mouse Models Of Experimental Asthma
Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from KrasG12D mice
Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein …
Rottlerin upregulates DDX3 expression in hepatocellular carcinoma
Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-δ in hemopoietic cells
Rottlerin-induced autophagy leads to apoptosis in bladder cancer cells
Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms
Rottlerin-induced BKCa channel activation impairs specific contractile responses and promotes vasodilation
Rottlerin-mediated inhibition of Chlamydia trachomatis growth and uptake of sphingolipids is independent of p38-regulated/activated protein kinase (PRAK)
Rottlerin-mediated inhibition of Toxoplasma gondii growth in BeWo trophoblast-like cells
Rottlerin, a novel protein kinase inhibitor
Rottlerin, a PKC isozyme‐selective inhibitor, affects signaling events and cytokine production in human monocytes
Rottlerin, a PKC-delta Inhibitor, Strongly Suppresses Cell Cycle Progression in Vascular Smooth Muscle Cell Through AMPK Activation.
Rottlerin, a polyphenolic compound from the fruits of Mallotus phillipensis (Lam.) Müll. Arg., impedes oxalate/calcium oxalate induced pathways of oxidative stress in …
Rottlerin, a specific inhibitor of protein kinase C-delta, impedes barrier repair response by increasing intracellular free calcium
Rottlerin, an inhibitor of protein kinase Cδ (PKCδ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to …
Rottlerin: a multifaced regulator of keratinocyte cell cycle
Rottlerin: An antibacterial agent and inhibitor of plasmid-mediated antibiotic resistance transfer
Rottlerin: an inappropriate and ineffective inhibitor of PKCδ
Rottlerin: bases for a possible usage in psoriasis
SALUBRIOUS EFFECT OF Rottlerin ON HYPEROXALURIA INDUCED OXIDATIVE DAMAGE IN RATS
Selective inhibition by Rottlerin of macropinocytosis in monocyte‐derived dendritic cells
Semisynthesis of mallotus B from rottlerin: evaluation of cytotoxicity and apoptosis-inducing activity
Sorafenib in combination with Rottlerin show an additive effects in renal cell carcinoma (RCC) cells.
Statin and Rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
Stimulation of suicidal erythrocyte death by Rottlerin
Sustained Release of Rottlerin Encapsulated within Poly (D, L-Lactic-co-Glycolic Acid) Nanoparticles Inhibits Migration and Clonogenicity in Pancreatic Cancer Cells
Synergism between PKCδ regulators hypericin and Rottlerin enhances apoptosis in U87 MG glioma cells after light stimulation
The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism
The effect of Rottlerin in calcium regulation in HMC‐1560 cells is mediated by a PKC‐δ independent effect
The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin
The Link between rottlerin, Na+, K+-ATPase activity and Na+-dependent glutamate transport
The mechanisms of proapoptotic effects of Rottlerin in pancreatic cancer cells involve interaction with Bcl-2 protein
The mosaic of rottlerin
The Mosaic of Rottlerin: The Sequel
The natural plant product Rottlerin activates Kv7. 1/KCNE1 channels
The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases’ cascade
The PKC delta inhibitor; rottlerin; induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases’ cascade
The protein kinase C delta inhibitor Rottlerin greatly stimulates apoptosis in pancreatic cancer cells
Therapeutic potential of Rottlerin for skin hyperpigmentary disorders by inhibiting the transcriptional activity of CREB-regulated transcription coactivators
Tumor suppressive role of Rottlerin in cancer therapy
Use of Rottlerin and its derivatives as activators of BK channel for therapy of hypertension and related disorders
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