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Rottlerin

  1. … (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn
  2. … Receptor Crosstalk: The IL-4-induced Alternate Pathway for BCR Signaling Operates in Parallel with the Classical Pathway, Is Sensitive to Rottlerin, and Depends on …
  3. 303 ENHANCED THERAPY SUCCESS OF RENAL CELL CARCINOMA USING TYROSINE KINASE INHIBITORS COMBINED WITH ROTTLERIN
  4. 64PEffects of Rottlerin and genistein through EF2K on proliferation, invasion and cell cycle/death in neuroblastoma cells
  5. A polyphenolic compound Rottlerin demonstrates significant in vitro cytotoxicity against human cancer cell lines: isolation and characterization from the fruits of …
  6. AB161. Rottlerin-induced autophagy leads to the apoptosis in bladder cancer cells
  7. Abstract LB-011: PAK1 inhibitor FRAX1036 sensitizes ovarian cancer cells with amplified 11q13 to cytotoxic effect of rottlerin
  8. Activation of BKCa Channels With Rottlerin Greatly Improves Cardiac Functional Improvement Following Surgical Ischemia Associated With Cardioplegic Arrest.
  9. Alternative pathways of cancer cell death by rottlerin: apoptosis versus autophagy
  10. Anti-allergic actions of Rottlerin from Mallotus philippinensis in experimental mast cell-mediated anaphylactic models
  11. Antiproliferative effect of Rottlerin on SK-MEL-28 melanoma cells
  12. Arsenite-Stimulated Glucose Uptake in 3T3-L1 Adipocytes Is Sensitive to Inhibition by Rottlerin and Ro-31-8220
  13. Biosynthesis of promatrix metalloproteinase-9/chondroitin sulphate proteoglycan heteromer involves a Rottlerin-sensitive pathway
  14. Coadministration of sorafenib with Rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells
  15. Critical appraisal of the MTT assay in the presence of Rottlerin and uncouplers
  16. Design, synthesis and functional characterization of Rottlerin analogs
  17. Determination of rottlerin, a natural protein kinases C inhibitor, in pancreatic cancer cells and mouse xenografts by RP-HPLC method
  18. Development and validation of a RP-HPLC method for quantification of Rottlerin in Kamala (Mallotus philppinensis).
  19. Development and validation of a RP-HPLC method for the simultaneous determination of Embelin, Rottlerin and Ellagic acid in Vidangadi churna
  20. Down-regulation of caspase-2 by Rottlerin via protein kinase C-δ–independent pathway
  21. Down-regulation of Caspase-2 by Rottlerin via Protein Kinase CD–Independent Pathway
  22. Effect of rottlerin, a PKC-δ inhibitor, on TLR-4-dependent activation of murine microglia
  23. Effects of Rottlerin on in vitro proliferation of and expressions of interleukin-17C, CCL20 and nuclear factor-κB in a human keratinocyte cell line HaCaT
  24. Effects of Rottlerin on silica-exacerbated systemic autoimmune disease in New Zealand mixed mice
  25. Effects of rottlerin, an inhibitor of calmodulin-dependent protein kinase III, on cellular proliferation, viability, and cell cycle distribution in malignant glioma cells.
  26. Effects of Rottlerin, an Inhibitor of Calmodulin-dependent Protein Kinase Ill, on Cellular Proliferation, Viability, and Cell Cycle Distribution in Malignant Glioma …
  27. Efficient synthesis of Rottlerin and its two subunits
  28. Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor Rottlerin and relative insensitivity towards staurosporine
  29. Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor Rottlerin and relative insensitivity towards staurosporine
  30. Expression of protein kinase c (pkc) isoforms and the effect of selective pkc-s inhibition by Rottlerin on the induction of apoptosis in acute promyelocytic leukemia
  31. Improved synergistic anticancer efficacy of quercetin in combination with PI-103, rottlerin, and G0 6983 against MCF-7 and RAW 264.7 cells
  32. Inhibition of amyloid fibril formation and disassembly of pre-formed fibrils by natural polyphenol rottlerin
  33. Inhibition of eukaryotic elongation factor-2 kinase mediates Rottlerin induced effects in apoptosis and cell proliferation inhibition in human pancreatic cancer cells.
  34. Inhibition of Notch-1 pathway is involved in rottlerin-induced tumor suppressive function in nasopharyngeal carcinoma cells
  35. Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing
  36. Integrated in Silico Docking and MOMA Simulation Methods Reveal Rottlerin as a Potent Janus kinase 2 (JAK2) Inhibitor
  37. Integrin signaling and cell spreading alterations by Rottlerin treatment of chick limb bud mesenchymal cells
  38. Kinase inhibitors tyrphostin 9 and Rottlerin block early steps of rabies virus cycle
  39. Links between L-glutamate transporters, Na+/K+-ATPase and cytoskeleton in astrocytes: evidence following inhibition with rottlerin
  40. Mechanisms of apoptosis-induction by rottlerin: therapeutic implications for B-CLL
  41. Mechanisms of Rottlerin-mediated inhibition of chlamydial growth
  42. Mo1954 Rottlerin Promotes Apoptosis and Autophagy in Pancreatic Stellate Cells via AMPK Activation
  43. Multi-Functional Role of Rottlerin, PKC-Delta Inhibitor, in Immune Cells and Cancer Cells
  44. Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells
  45. Neuroprotective effect of protein kinase Cδ inhibitor Rottlerin in cell culture and animal models of Parkinson’s disease
  46. Non-conventional Rottlerin anticancer properties
  47. NOX, RAS and PKC-Δ as Key Players in Kidney Diseases: A Possible Role of Rottlerin
  48. Phosphorylation-independent mTORC1 inhibition by the autophagy inducer Rottlerin
  49. Possible mechanism of Rottlerin induced modulation of ischemia reperfusion injury in isolated rat hearts
  50. Potent stimulation of large‐conductance Ca2+‐activated K+ channels by rottlerin, an inhibitor of protein kinase C‐δ, in pituitary tumor (GH3) cells and in cortical …
  51. Potential in for PKC inhibitor Rottlerin in murine experimental model of asthma
  52. Potentiation of tumor necrosis factor-α-induced cell death by Rottlerin through a cytochrome-c-independent pathway
  53. Prevention of TNF-induced necrotic cell death by Rottlerin through a Nox1 NADPH oxidase
  54. Protection of human colon epithelial cells against deoxycholate by rottlerin
  55. Protein kinase C-δ inhibitor, Rottlerin inhibits growth and survival of mycobacteria exclusively through Shikimate kinase
  56. Protein kinase C‐delta is commonly expressed in multiple myeloma cells and its downregulation by Rottlerin causes apoptosis
  57. Receptor Activator of Nuclear Factor-icB Is Induced by a Rottlerin-sensitive and p38 MAP Kinase-dependent Pathway during Monocyte Differentiation.
  58. Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation
  59. Research Article Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy
  60. Research Article Rottlerin Inhibits ROS Formation and Prevents NFκB Activation in MCF-7 and HT-29 Cells
  61. Reversal of the negative effects of TGFβ1 on human articular chondrocytes by PKCδ inhibition with rottlerin
  62. Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues
  63. Rottlerin and cancer: novel evidence and mechanisms
  64. Rottlerin and curcumin: a comparative analysis
  65. Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma
  66. Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies
  67. Rottlerin causes pulmonary edema in vivo: a possible role
  68. Rottlerin causes pulmonary edema in vivo: a possible role for PKCδ
  69. Rottlerin Derivatives and Other Compounds from Mallotus philippinensis Fruits and Their Potential Antimycobactrial Activity
  70. Rottlerin diminished the lipid accumulation in 3T3-L1 cell line and enhanced the uncoupling of oxidative phosphorylation in D16 cell line via LRP6 mediated pathway
  71. Rottlerin dissolves pre-formed protein amyloid: A study on hen egg white lysozyme
  72. Rottlerin enhances IL-1β-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells
  73. Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells
  74. Rottlerin exhibits anti-cancer effect through inactivation of S phase kinase-associated protein 2 in pancreatic cancer cells
  75. Rottlerin Exhibits Antiangiogenic Effects In vitro
  76. Rottlerin exhibits antitumor activity via down-regulation of TAZ in non-small cell lung cancer
  77. Rottlerin greatly improves cardiac functional recovery following ischemic cardioplegic arrest (CP) in wild-type but not BKCa channel knockout mice
  78. Rottlerin impairs the formation and maintenance of psychostimulant-supported memory
  79. Rottlerin Increases Cardiac Contractile Performance and Coronary Perfusion Through BKCa++ Channel Activation After Cold Cardioplegic Arrest in Isolated Hearts
  80. Rottlerin induce early autophagy and late apoptosis via PKC-delta independent pathway.
  81. Rottlerin induced autophagy by targeting multiple sites that leads to the apoptosis in cancer stem cells
  82. Rottlerin induces a transformed phenotype in human keratinocytes
  83. Rottlerin induces apoptosis in pancreatic cancer cells through the interaction with Bcl-2 family proteins
  84. Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism
  85. Rottlerin induces apoptosis of human blood eosinophils: A possible role for PKC-[delta] in mediating eosinophil survival
  86. Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC δ-independent mechanism in human malignant tumor cells
  87. Rottlerin Induces Apoptosis via Death Receptor5 (DR5) Up-Regulation through CHOP-Dependent and PKC d-Independent Mechanism in Human Malignant Tumor …
  88. Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
  89. Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of …
  90. Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
  91. Rottlerin induces calcium influx and protein degradation in cultured lenses independent of effects on protein kinase Cδ
  92. Rottlerin induces cyclooxygenase-2 upregulation through an ATF4 and reactive oxygen species-independent pathway in HEI-OC1 cells
  93. Rottlerin induces ER stress-mediated cell death in pancreatic stellate cells
  94. Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC δ-independent pathway in human colon …
  95. Rottlerin Induces Heme Oxygenase-1 through ROS generation, p38 and Akt Phosphorylation and Nrf2/ARE Activation in Human Colon Cancer HT29 Cells
  96. Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-δ-independent pathway in human colon cancer cells
  97. Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells
  98. Rottlerin inhibitis agonist-stimulated tyrosine phosphorylation (TyrP), MAPK activation, and amylase secretion by depleting intracellular ATP in rat …
  99. Rottlerin Inhibits (Na+, K+)-ATPase Activity in Brain Tissue and Alters d-Aspartate Dependent Redistribution of Glutamate Transporter GLAST in Cultured Astrocytes
  100. Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-Aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes
  101. Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cells
  102. Rottlerin inhibits cell growth and invasion via down-regulation of EZH2 in prostate cancer
  103. Rottlerin inhibits cell growth, induces apoptosis and cell cycle arrest, and inhibits cell invasion in human hepatocellular carcinoma
  104. Rottlerin inhibits chlamydial intracellular growth and blocks chlamydial acquisition of sphingolipids from host cells
  105. Rottlerin inhibits human T cell responses
  106. Rottlerin inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes by uncoupling mitochondrial oxidative phosphorylation
  107. Rottlerin inhibits Lonicera japonica-induced photokilling in human lung cancer cells through cytoskeleton-related signaling cascade
  108. Rottlerin inhibits migration of follicular thyroid carcinoma cells by PKCδ‐independent destabilization of the focal adhesion complex
  109. Rottlerin inhibits migration of thyroid follicular carcinoma through destablization of the focal adhesion complex
  110. Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes
  111. Rottlerin inhibits P2X7 receptor‐stimulated phospholipase D activity in chronic lymphocytic leukaemia B‐lymphocytes
  112. Rottlerin Inhibits ROS Formation and Prevents NF 𝜅 B Activation in MCF-7 and HT-29 Cells
  113. Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-δ …
  114. Rottlerin inhibits the nuclear factor κB/Cyclin-D1 cascade in MCF-7 breast cancer cells
  115. Rottlerin inhibits tonicity-dependent expression and action of TonEBP in a PKCδ-independent fashion
  116. Rottlerin is a mitochondrial uncoupler that decreases cellular ATP
  117. Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cδ tyrosine phosphorylation
  118. Rottlerin is a pan phosphodiesterase inhibitor and can induce neurodifferentiation in IMR-32 human neuroblastoma cells
  119. Rottlerin Mediated Modulation of Tonicity-Responsive Enhancer Binding Protein (TonEBP) In Wistar Rats
  120. Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I …
  121. Rottlerin promotes apoptosis and autophagy in pancreatic stellate cells via AMPK activation
  122. Rottlerin promotes autophagy and apoptosis in gastric cancer cell lines
  123. Rottlerin protected dopaminergic cell line from cytotoxicity of 6-hydroxydopamine by inhibiting PKCδ phosphorylation
  124. Rottlerin Reduces cAMP/CREB-Mediated Melanogenesis via Regulation of Autophagy
  125. Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria …
  126. Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
  127. Rottlerin stimulates apoptosis in pancreatic cancer
  128. Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family
  129. Rottlerin stimulates apoptosis in pancreatic cancer through inhibition of Bcl-xL
  130. Rottlerin stimulates metallothionein gene expression but inhibits metal transport in Chinese hamster ovary cells
  131. Rottlerin Suppresses Airway Hyperreactivity And Inflammation In Mouse Models Of Experimental Asthma
  132. Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from KrasG12D mice
  133. Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein …
  134. Rottlerin upregulates DDX3 expression in hepatocellular carcinoma
  135. Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-δ in hemopoietic cells
  136. Rottlerin-induced autophagy leads to apoptosis in bladder cancer cells
  137. Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms
  138. Rottlerin-induced BKCa channel activation impairs specific contractile responses and promotes vasodilation
  139. Rottlerin-mediated inhibition of Chlamydia trachomatis growth and uptake of sphingolipids is independent of p38-regulated/activated protein kinase (PRAK)
  140. Rottlerin-mediated inhibition of Toxoplasma gondii growth in BeWo trophoblast-like cells
  141. Rottlerin, a novel protein kinase inhibitor
  142. Rottlerin, a PKC isozyme‐selective inhibitor, affects signaling events and cytokine production in human monocytes
  143. Rottlerin, a PKC-delta Inhibitor, Strongly Suppresses Cell Cycle Progression in Vascular Smooth Muscle Cell Through AMPK Activation.
  144. Rottlerin, a polyphenolic compound from the fruits of Mallotus phillipensis (Lam.) Müll. Arg., impedes oxalate/calcium oxalate induced pathways of oxidative stress in …
  145. Rottlerin, a specific inhibitor of protein kinase C-delta, impedes barrier repair response by increasing intracellular free calcium
  146. Rottlerin, an inhibitor of protein kinase Cδ (PKCδ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to …
  147. Rottlerin: a multifaced regulator of keratinocyte cell cycle
  148. Rottlerin: An antibacterial agent and inhibitor of plasmid-mediated antibiotic resistance transfer
  149. Rottlerin: an inappropriate and ineffective inhibitor of PKCδ
  150. Rottlerin: bases for a possible usage in psoriasis
  151. SALUBRIOUS EFFECT OF Rottlerin ON HYPEROXALURIA INDUCED OXIDATIVE DAMAGE IN RATS
  152. Selective inhibition by Rottlerin of macropinocytosis in monocyte‐derived dendritic cells
  153. Semisynthesis of mallotus B from rottlerin: evaluation of cytotoxicity and apoptosis-inducing activity
  154. Sorafenib in combination with Rottlerin show an additive effects in renal cell carcinoma (RCC) cells.
  155. Statin and Rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
  156. Stimulation of suicidal erythrocyte death by Rottlerin
  157. Sustained Release of Rottlerin Encapsulated within Poly (D, L-Lactic-co-Glycolic Acid) Nanoparticles Inhibits Migration and Clonogenicity in Pancreatic Cancer Cells
  158. Synergism between PKCδ regulators hypericin and Rottlerin enhances apoptosis in U87 MG glioma cells after light stimulation
  159. The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism
  160. The effect of Rottlerin in calcium regulation in HMC‐1560 cells is mediated by a PKC‐δ independent effect
  161. The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin
  162. The Link between rottlerin, Na+, K+-ATPase activity and Na+-dependent glutamate transport
  163. The mechanisms of proapoptotic effects of Rottlerin in pancreatic cancer cells involve interaction with Bcl-2 protein
  164. The mosaic of rottlerin
  165. The Mosaic of Rottlerin: The Sequel
  166. The natural plant product Rottlerin activates Kv7. 1/KCNE1 channels
  167. The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases’ cascade
  168. The PKC delta inhibitor; rottlerin; induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases’ cascade
  169. The protein kinase C delta inhibitor Rottlerin greatly stimulates apoptosis in pancreatic cancer cells
  170. Therapeutic potential of Rottlerin for skin hyperpigmentary disorders by inhibiting the transcriptional activity of CREB-regulated transcription coactivators
  171. Tumor suppressive role of Rottlerin in cancer therapy
  172. Use of Rottlerin and its derivatives as activators of BK channel for therapy of hypertension and related disorders
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