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Reversing Obesity
Reversing Obesity
Reversal of obesity by targeted ablation of adipose tissue
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
Reversal of obesity-related hypoadiponectinemia by lifestyle intervention: a controlled, randomized study in obese adolescents
Reversal of diet-induced obesity and diabetes in C57BL/6J mice
Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats
Leptin Activation of Corticosterone Production in Hepatocytes May Contribute to the Reversal of Obesity and Hyperglycemia in Leptin-Deficient ob/ob Mice
Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a β3-adrenoceptor agonist
Trends in fatness and the origins of obesity
Reversal of obesity in the genetically obese fa/fa Zucker rat with an ephedrine/methylxanthines thermogenic mixture
Reversal of Obesity-and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption….
Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity
Obesity and sarcopenia after menopause are reversed by sex hormone replacement therapy
Myocardial fatty acid oxidation rates remain elevated in ob/ob mice despite reversal of obesity and diabetes by caloric restriction
Body weight regulation in obese and obese-reduced rats.
Inflammation and the IKKβ/IκB/NF-κB axis in obesity-and diet-induced insulin resistance
Polycythemia of obesity: further studies of its mechanism and a report of two additional cases
Brain responses to obesogenic diets and diet-induced obesity
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
Hypothalamic obesity: the autonomic hypothesis and the lateral hypothalamus
Role of Endoplasmic Reticulum Stress and c-Jun NH2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and Diabetes
Severe orthostatic hypotension following weight reduction surgery
The role of beta3-adrenergic receptors in control of brown and white adipose tissues and of energy balance: Reversal of obesity by CL 316,243, a new beta3 …
The liver in obesity and type 2 diabetes mellitus
Effects of fasting and refeeding on blood pressure are determined by nutritional state, not by body weight change
Maternal obesity is associated with younger age at obesity onset in US adolescent offspring followed into adulthood
Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue
The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity
Using mouse models to dissect the genetics of obesity
Energy balance in reversible obesity
Effect of diet on adipose tissue and skeletal muscle VLDL receptor and LPL: implications for obesity and hyperlipidemia
Pathophysiologic changes of obesity
Role of the autonomic nervous system in the development of ventromedial hypothalamic obesity
Aspirin as a promoter of ephedrine-induced thermogenesis: potential use in the treatment of obesity
The effects of subdiaphragmatic vagotomy in rats with ventromedial hypothalamic obesity
Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity
Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation
Pathogenesis of type 2 diabetes mellitus
Internal regulation and the evolution of normal growth as the basis for prevention of obesity in children
A novel IKKβ inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance
Obesity and alcoholic liver disease
Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid–induced insulin resistance
The growing problem of obesity in dogs and cats
The cross cultural context of obesity: an INCLEN multicentre collaborative study
Leptin: the link between adipose tissue and reproductive system
Reduction of diet-induced obesity in rats with a herbal formulation
Inflammation in obesity is a common link between defects in fatty acid metabolism and insulin resistance
Increase in prevalence of obesity and diabetes and decrease in plasma cholesterol in a central Australian aboriginal community
Obesity, past present and future
Is there a metabolic rationale to support a weight loss programme to prevent diabetes?
Five-year obesity incidence in the transition period between adolescence and adulthood: the National Longitudinal Study of Adolescent Health
Increased CD36 protein as a response to defective insulin signaling in macrophages
Adipose stress-sensing kinases: linking obesity to malfunction
Diabetes and the endocrine pancreas II
Controlling Obesity: School, Work, and Leisure
Reduced skeletal muscle inhibitor of κBβ content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training
Hyperphagia and obesity following ventromedial hypothalamic lesions in rats with subdiaphragmatic vagotomy
The biology of white adipocyte proliferation
Physical activity mediates a healthier body weight in the presence of obesity
The dysregulated adipose tissue: a connecting link between insulin resistance, type 2 diabetes mellitus and atherosclerosis
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance
The hypothalamic‐pituitary‐adrenal axis activity in obesity and the metabolic syndrome
Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety
Insulin resistance: a phosphorylation-based uncoupling of insulin signaling
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
Hyperinsulinemia in rats with hypothalamic obesity: effects of autonomic drugs and glucose
in Obesity and Diabetes
Regulation of 11β‐HSD Genes in Human Adipose Tissue: Influence of Central Obesity and Weight Loss
Adrenal and gonadal function in obesity
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
Nitrosative stress and pathogenesis of insulin resistance
The genetics of human obesity
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Neuropeptides, appetite regulation, and human obesity
DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet
Adipokines: molecular links between obesity and atheroslcerosis
Plasminogen activator inhibitor-1, inflammation, obesity, insulin resistance and vascular risk
Adipokines: at the heart of the relationship between obesity and insulin resistance.
The metabolic syndrome as a risk factor for chronic kidney disease: more than a fat chance?
Obesity: overview of prevalence, etiology, and treatment
Adipokines, inflammation, and the endothelium in diabetes
A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice
Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85α: the two sides of a coin
Low-grade inflammation, obesity, and insulin resistance in adolescents
Surgical management of obesity
Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible
Subclinical inflammation and obesity, diabetes and related disorders
Optimal management of the morbidly obese patient SAGES appropriateness conference statement
Dietary Cyanidin 3-O-β-D-Glucoside-Rich Purple Corn Color Prevents Obesity and Ameliorates Hyperglycemia in Mice
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
Metabolic syndrome, hyperinsulinemia, and cancer
Evidence for alteration of the vitamin D-endocrine system in obese subjects.
Pharmacological treatment of obesity: therapeutic strategies
A rational approach to pathogenesis and treatment of type 2 diabetes mellitus, insulin resistance, inflammation, and atherosclerosis
Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells
Neuroendocrine and metabolic effects of adipocyte-derived hormones
Cellular inflammatory responses: novel insights for obesity and insulin resistance
Tumor necrosis factor and its potential role in insulin resistance and nonalcoholic fatty liver disease
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
Obesity-induced inflammatory changes in adipose tissue
A burning question: does an adipokine-induced activation of the immune system mediate the effect of overnutrition on type 2 diabetes?
Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance
Obesity and androgens: facts and perspectives
Antidiabetic Effects of cis-9, trans-11–Conjugated Linoleic Acid May Be Mediated via Anti-Inflammatory Effects in White Adipose Tissue
Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes
Search for obesity drugs: targeting central and peripheral pathways
#VALUE!
Adipsin and an endogenous pathway of complement from adipose cells.
Decreased insulin receptor (IR) autophosphorylation in fibroblasts from patients with PCOS: effects of serine kinase inhibitors and IR activators
Surgery for obesity: a review of the current state of the art and future directions
Regulation of energy balance in two models of reversible obesity in the rat.
Type 2 diabetes: principles of pathogenesis and therapy
The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
Comparison of short-term diet and exercise on insulin action in individuals with abnormal glucose tolerance
Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
Pathophysiology of obesity-induced insulin resistance and type 2 diabetes mellitus
Inhibitors of preadipocyte replication: opportunities for the treatment of obesity
Obesity and endothelial function
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
Laparoscopic Roux-en-Y gastric bypass for recalcitrant gastroesophageal reflux disease in morbidly obese patients
The evolving role of inflammation in obesity and the metabolic syndrome
Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-κB pathway in rat liver
7 Bariatric Surgery for Obesity
Adipose tissue macrophages
Nonalcoholic fatty liver disease and the epidemic of obesity
The Prevalence and Treatment of Obesity in Adolescence (Weight Control)
Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone
MCH−/− Mice Are Resistant to Aging-Associated Increases in Body Weight and Insulin Resistance
Inflammation, stress, and diabetes
Novel targets and therapeutic strategies for type 2 diabetes
Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
Macrophage-secreted factors induce adipocyte inflammation and insulin resistance
Insulin sensitizers may prevent metabolic inflammation
Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats
Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance
Effects of gonadectomy on glucocorticoid metabolism in obese Zucker rats
Oxidative inflammatory stress in obesity and diabetes
Combined leptin actions on adipose tissue and hypothalamus are required to deplete adipocyte fat in lean rats: implications for obesity treatment
Inflammation, atherosclerosis, and aspects of insulin action
Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes
Increased insulin and leptin sensitivity in mice lacking acyl CoA: diacylglycerol acyltransferase 1
Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study
Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-α
11β-Hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome
Effect of a β-3 agonist on food intake in two strains of rats that differ in susceptibility to obesity
Tackling obesities: future choices-project report
Role of Ser/Thr kinases in the uncoupling of insulin signaling
Obesity, peroxisome proliferator-activated receptor, and atherosclerosis in type 2 diabetes
Transplantation of pancreatic beta-cells prevents development of hypothalamic obesity in rats.
An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial
Anti‐Inflammatory and Antidiabetic Roles of PPARγ
Emerging pharmacological approaches to the treatment of obesity
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study
Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences
Increased glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db …
Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance
Current knowledge in the neurophysiologic modulation of obesity
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.
Role of energy charge and AMP-activated protein kinase in adipocytes in the control of body fat stores
Regulated membrane transport of free fatty acids in adipocytes: role in obesity and non-insulin dependent diabetes mellitus.
Weight loss increases 11β-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue
New approaches in the pharmacological treatment of obesity
Leptin and the treatment of obesity: its current status
Short-and long-term beneficial effects of a multidisciplinary therapy for the control of metabolic syndrome in obese adolescents
Inflammation and insulin resistance
Reduced adipose glucocorticoid reactivation and increased hepatic glucocorticoid clearance as an early adaptation to high-fat feeding in Wistar rats
Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-facp) rats
Insulin signalling and the regulation of glucose and lipid metabolism
Obesity-related differential gene expression in the visceral adipose tissue
Aging up-regulates expression of inflammatory mediators in mouse adipose tissue
IKK-β links inflammation to obesity-induced insulin resistance
Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea
Adipose tissue as source and target for novel therapies
Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial
Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals
Keynote review: the adipocyte as a drug discovery target
Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats
Obesity, inflammation, and insulin resistance
Genistein decreases food intake, body weight, and fat pad weight and causes adipose tissue apoptosis in ovariectomized female mice
Diabetes and obesity: part 1
Molecular and genetic studies examining the inflammatory consequences of obesity
Prevention of genetic fa/fa obesity with an ephedrine-methylxanthines thermogenic mixture
Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and …
Obesity: Overview & Management
Improvement in risk factors for metabolic syndrome and insulin resistance in overweight youth who are treated with lifestyle intervention
C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study
Inflammatory mechanisms in diabetes: lessons from the β-cell
Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals
Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings
Type 2 diabetes and obesity in children and adolescents: experience from studies in Taiwanese population
Ceramides in insulin resistance and lipotoxicity
Resistin-and obesity-associated metabolic diseases
Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
The emerging role of adipokines as mediators of cardiovascular function: physiologic and clinical perspectives
A primer on bariatric surgery: treatment of last resort for morbid obesity
Anti-obesity and anti-tumor pro-apoptotic peptides are sufficient to cause release of cytochrome c from vesicles
Obesity, insulin resistance, and renal function
Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
New drug targets for type 2 diabetes and the metabolic syndrome
Diet-induced obesity and acute hyperlipidemia reduce IκBα levels in rat skeletal muscle in a fiber-type dependent manner
Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fats⃞
Diabesity: an inflammatory metabolic condition
Peroxisome proliferator-activated receptor-α deficiency does not alter insulin sensitivity in mice maintained on regular or high-fat diet: hyperinsulinemic-euglycemic …
Pathogenic role of inflammatory cytokines in obesity: from insulin resistance to diabetes mellitus
Thiazolidinediones influence plasma steroids of male obese Zucker rats
Loss of cyclin‐dependent kinase inhibitors produces adipocyte hyperplasia and obesity
Beyond the scale: understanding mechanisms of weight gain and obesity in diabetes
Adiponectin and hypertension: a putative link between adipocyte function and atherosclerotic risk?
Sibutramine-dependent brown fat activation in rats: an immunohistochemical study
12: Does physical activity help weight loss in obesity?
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
Heterogeneity of adipose tissue metabolism
The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans
The anti-inflammatory and potential anti-atherogenic effect of insulin: a new paradigm
Prevalence, predisposition and prevention of type II diabetes
Neurohumoral regulation of body weight gain
Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-κB and IκB kinase pathway to regulate the release of proinflammatory cytokines from human adipose …
Induction of heat shock proteins may combat insulin resistance
Obesity in Later Childhood and Countermeasures
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
2 Steps for the Medical Evaluation of the Obese Patient
Exercise alone reduces insulin resistance in obese children independently of changes in body composition
Evolutionary origins of insulin resistance: a behavioral switch hypothesis
TLR4 links innate immunity and fatty acid–induced insulin resistance
Improving effect of carteolol on bodyweight and carbohydrate and lipid metabolic responses in the OLETF rat
Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db …
Are oxidative stress− activated signaling pathways mediators of insulin resistance and β-cell dysfunction?
PKC-mediated modulation of L-type calcium channels may contribute to fat-induced insulin resistance
11 [beta]-hydroxysteroid dehydrogenase type 1 in obesity
Role of adipocytokines in metabolism and disease
New insights into the pathophysiology of gestational diabetes mellitus: possible role of human leukocyte antigen-G
Factors influencing body weight regulation
Inhibitor κB kinase is involved in the paracrine crosstalk between human fat and muscle cells
Mechanisms of the antidiabetic effects of the β3-adrenergic agonist CL-316243 in obese Zucker-ZDF rats
Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain
Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo
Contribution of sphingolipids to the pathogenesis of obesity
Autoamplification of tumor necrosis factor-α: a potential mechanism for the maintenance of elevated tumor necrosis factor-α in male but not female obese mice
Insulin receptor substrate proteins and diabetes
Neuroendocrinology of insulin resistance: metabolic and endocrine aspects of adiposity
Increase in insulin action and fat oxidation after treatment with CL 316,243, a highly selective beta3-adrenoceptor agonist in humans.
Interleukin-6 induces cellular insulin resistance in hepatocytes
Les relations entre obésité, inflammation et insulinorésistance: acquisitions récentes
Tumor necrosis factor-α suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-κB activation by …
Acetylsalicylic acid improves lipid-induced insulin resistance in healthy men
A sympathetic defense against obesity
Sex steroids and leptin regulate 11β-hydroxysteroid dehydrogenase I and P450 aromatase expressions in human preadipocytes: sex specificities
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins …
Unexpected deposition of brown fat in mammary gland during postnatal development
Potential utility of natural polyphenols for reversing fat-induced insulin resistance
Turning down insulin signaling
Female rats do not exhibit free fatty acid–induced insulin resistance
A clinical guide to pediatric weight management and obesity
Fat, diabetes, and liver injury in chronic hepatitis C
Molecular basis of insulin action
Diabetic pregnancy in rats leads to impaired glucose metabolism in offspring involving tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 …
Control of body weight: a physiologic and transgenic perspective
Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro
Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice
Skeletal muscle and obesity
SR59230A blocks β3-adrenoceptor-linked modulation of uncoupling protein-1 and leptin in rat brown adipocytes
Adipose tissue remodeling and malfunctioning in obesity revealed by in vivo molecular imaging
Muscle triglyceride and insulin resistance
Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
Risk factors for progression to incident hyperinsulinemia: the Atherosclerosis Risk in Communities Study, 1987–1998
Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy
Studies on the sympathetic efferent nerves of brown adipose tissue of lean and obese Zucker rats
Antioxidants: do they have a role in the treatment of insulin resistance?
Transcriptional control of brown fat determination by PRDM16
AAV-mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats
Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
Preclinical developments in type 2 diabetes
NEUROPEPTIDE, OPIOID RECEPTOR, AND BEHAVIORAL CHANGES FOLLOWING OBESITY-INDUCING VENTROMEDIAL HYPOTHALAMIC LESIONS …
Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines
Disordered lipid metabolism and the pathogenesis of insulin resistance
Lifestyle modification and endothelial function in obese subjects
White adipose tissue contributes to UCP1-independent thermogenesis
Insulin resistance, inflammation, and the IKK/IκB/NF-κB pathway
ALS/Lt: a new type 2 diabetes mouse model associated with low free radical scavenging potential
Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms
Lipids and glucose in type 2 diabetes: what is the cause and effect?
Type 1 diabetes is associated with increased cyclooxygenase-and cytokine-mediated inflammation
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Insulin signaling pathways in time and space
NASH as part of the metabolic (insulin resistance) syndrome
Dehydroepiandrosterone inhibits the amplification of glucocorticoid action in adipose tissue
Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue
Energy metabolism in genetically fat and lean birds and mammals
Insulin resistance, inflammation, and the ikk/ikb/nf-kb pathway
Insulin resistance in NAFLD: Potential mechanisms and therapies
Pathogenesis of type 2 diabetes
The role of AEBP1 in sex-specific diet-induced obesity
Mitochondrial dysfunction and type 2 diabetes
Nitric oxide-induced downregulation of leptin production by 3T3-L1 adipocytes
Insulin resistance, inflammation, and the IKK/IкB/NF-кB pathway
Aspirin and diabetes: inhibition of amylin aggregation by nonsteroidal anti-inflammatory drugs
LXRs regulate the balance between fat storage and oxidation
Tag Polymorphisms at the A20 (TNFAIP3) Locus Are Associated With Lower Gene Expression and Increased Risk of Coronary Artery Disease in Type 2 Diabetes
Adiponectin: a key fat-derived molecule regulating inflammation
The inflammatory response is an integral part of the stress response: Implications for atherosclerosis, insulin resistance, type II diabetes and metabolic syndrome X
Future Pharmacotherapy for Obesity: Integration of Metabolism and Body Weight Regulation
Inflammation and its relationship to insulin resistance, type 2 diabetes mellitus, and endothelial dysfunction
Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B in …
PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
Effect of a high or low ambient perinatal temperature on adult obesity in Osborne-Mendel and S5B/Pl rats
The effect of tea polyphenols on chronic disease: obesity, the metabolic syndrome, and colon cancer
Abscisic acid ameliorates glucose tolerance and obesity-induced inflammation
Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway
C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes
The Apparent Increase in Insulin Sensitivity of Leptin-Treated Rats Appears to be Due to a Decrease in Blood Glucose Concentrations in Response to Fasting
Long-term multidisciplinary therapy decreases predictors and prevalence of metabolic syndrome in obese adolescents
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Not the next tobacco: Defenses to obesity claims
Obesity and nutrition
Drug Therapy for Insulin Resistance—a Look at the Future
Adiponectin oligomers in human serum during acute and chronic exercise: relation to lipid metabolism and insulin sensitivity
Kinase-dependent pathways and the development of insulin resistance in hepatocytes
Effect of high-fat diet on KKAy and ob/ob mouse liver and adipose tissue corticosterone and 11-dehydrocorticosterone concentrations
Mechanisms of insulin resistance in humans and possible links with inflammation
Development and evaluation of a nutrition curriculum to prevent obesity in inner-city teens
Cardiac-specific overexpression of peroxisome proliferator–activated receptor-α causes insulin resistance in heart and liver
Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitus
Increased glucose uptake promotes oxidative stress and PKC-δ activation in adipocytes of obese, insulin-resistant mice
Molecular and cellular aspects of insulin resistance: implications for diabetes
Receptors for insulin, NSILA-s, and growth hormone: applications to disease states in man
Non-alcoholic fatty liver disease and insulin resistance
Role of oxidative stress and inflammation in the origin of Type 2 diabetes–a paradigm shift
Serum concentrations of resistin-like molecules β and γ are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract …
Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis
Energy expenditure, body composition, and glucose metabolism in lean and obese rhesus monkeys treated with ephedrine and caffeine
Role of the Toll-like receptor 4/NF-κB pathway in saturated fatty acid–induced inflammatory changes in the interaction between adipocytes and macrophages
Salicylates targeting insulin resistance
COMMENT: Genetic Variability in Insulin Action Inhibitor Ikkβ (IKBKB) Does Not Play a Major Role in the Development of Type 2 Diabetes
Lowering plasma free fatty acids with Acipimox mimics the antidiabetic effects of the [beta] 3-adrenergic agonist CL-316243 in obese Zucker diabetic fatty rats
Bradykinin Augments Insulin-Stimulated Glucose Transport in Rat Adipocytes via Endothelial Nitric Oxide Synthase–Mediated Inhibition of Jun NH2-Terminal Kinase
Obesity-associated interleukin-6 contributes to hepatic insulin resistance in mice
Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling
Feeding scallop shell powder induces the expression of uncoupling protein 1 (UCP1) in white adipose tissue of rats
The macrophage at the crossroads of insulin resistance and atherosclerosis
Molecular mechanisms of diabetic vasculopathy
Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle …
Central nervous system regulation of fat cell lipid mobilization: The role of the sympathetic nervous system
Treatment of insulin resistance in diabetes mellitus
Adiponectin and leptin: potential tools in the differential diagnosis of pediatric diabetes?
Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis
Sympathetic innervation of white adipose tissue and its regulation of fat cell number
Mechanisms underlying fat-induced hepatic insulin resistance
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Metabolic and cellular plasticity in white adipose tissue I: effects of β3-adrenergic receptor activation
Insulin is an anti-inflammatory and anti-atherosclerotic hormone
Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines
Free fatty acid-induced insulin resistance in the obese is not prevented by rosiglitazone treatment
Phosphorylation of fetuin-A, a physiological inhibitor of insulin action, regulated by insulin and leptin
Functional characterization of resistin, a novel adipokine
Regulating insulin signaling and β-cell function through IRS proteins
Role of cyclin-dependent kinase inhibitors in estrogen regulation of adipogenesis
The effect of salicylates on insulin sensitivity
Adipokine expression and secretion: a target for pharmacologic treatment
Cells of the stroma-vascular fraction of human adipose tissue: characterization and function
Modulation of insulin action
Advanced-glycation end products in insulin-resistant states
Pathophysiology of NASH: insulin resistance, free fatty acids and oxidative stress
The hormone leptin reduces body weight. A mutant gene makes the mouse obese
Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes
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Effects of pioglitazone on promoting energy storage, not expenditure, in brown adipose tissue of obese fa/fa Zucker rats: comparison to CL 316,243
PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
Inflammatory markers and type 2 diabetes
The β3-adrenergic agonist CL316, 243 inhibits insulin signaling but not glucose uptake in primary human adipocytes
Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-α induction of p38 and p42/p44 mitogen-activated protein …
Adipocyte differentiation induces dynamic changes in NF-κB expression and activity
25 Insulin Resistance Syndrome and Its Vascular Complications
Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients?
Association between Helicobacter felis—Induced Gastritis and Elevated Glycated Hemoglobin Levels in a Mouse Model of Type 1 Diabetes
Neuropeptide and peripheral hormone crosstalk with adipocyte function
Prevention of cardiovascular complications of diabetes mellitus by aspirin
THE ANTI-INFLAMMATORY AND POTENTIAL ANTI-ATHEROGENIC EFFECT OF INSULIN
Selenium acts as an insulin-like molecule for the down-regulation of diabetic symptoms via endoplasmic reticulum stress and insulin signalling proteins in diabetes …
The aging pancreas, glucose tolerance and insulin action
Correction of insulin resistance and the metabolic syndrome
Endothelium, inflammation, and diabetes
Prevention of fat-induced insulin resistance by salicylate
Patents in Targets and Drugs for Insulin Resistance: Correlation with Inflammatory Mediators
Treating insulin resistance: future prospects
Transgenic Models of Impaired Insulin Signaling
Insulin resistance, hypertension and endothelial dysfunction
The expanding scope of the metabolic syndrome and implications for the management of cardiovascular risk in type 2 diabetes with particular focus on the emerging …
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle
Adult stem cells for cardiovascular diseases: the adipose tissue potential
A role of vitamin D in low-intensity chronic inflammation and insulin resistance in type 2 diabetes mellitus?
Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment
Investigation of the alternative pathway of complement in the biology of white and brown adipocytes
Effectiveness of a Christian faith-based program for weight loss
Increased in vivo phosphorylation of insulin receptor at serine 994 in the liver of obese insulin-resistant Zucker rats
Glucocorticoid administration: Studies on weight regulation and metabolic implications
Role of insulin resistance and insulin secretory dysfunction in the pathogenesis of type 2 diabetes mellitus: lessons from cross-sectional, prospective, and longitudinal …
The relationship between high-fat feeding, insulin resistance, and TNF-α gene expression in growing rats
β1 to β3 Switch in Control of Cyclic Adenosine Monophosphate during Brown Adipocyte Development Explains Distinct β-Adrenoceptor Subtype Mediation of …
Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism
The metabolic and molecular regulation of adipose triglyceride lipase
Short-term lifestyle intervention significantly increases fasting adiponectin and induces a decline in serum adiponectin during oral glucose tolerance test, without …
Aspirin and diabetes
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
Antioxidants in diabetic complications and insulin resistance
Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non–platelet-mediated effects
IRS proteins and the common path to diabetes
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
Syndromes of Severe Insulin Resistance (SSIRs)
Suppression of DGAT2 Expression Improves Hepatic Steatosis and Prevents Fat Induced Insulin Resistance
Timp3 deficiency in insulin receptor–haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-α
Impact of trans-10, cis-12 conjugated linoleic acid on interleukin (IL)-6 and IL-8 and adipogenic genes in cultures of human adipose tissue explants
STAT‐3 and the liver: A new station on our way to understand diabetes?
Functional anatomy of the ‘Adipose Organ’
Molecular basis of coordination of adipocyte metabolic and inflammatory responses
Age-and sex-related reference values for serum insulin concentration and its biological determinants in a French healthy population. The STANISLAS cohort
Macrophage peroxisome proliferator activated receptor γ as a therapeutic target to combat type 2 diabetes
Cell Signaling Properties of a-Lipoic Acid: Implications in Type 2 Diabetes
an unexpected virus–host interaction–the hepatitis C virus‐diabetes link
Comparison of isoenergetic aerobic versus aerobic plus resistance exercise program during a weight loss program
Tumor necrosis factor α produces insulin resistance in skeletal muscle by activation of inhibitor κB kinase in a p38 MAPK-dependent manner
Real-time RT-PCR and proteomic analysis of adipose tissue from ob/ob mice treated with leptin
Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance
The role of GSK3 in glucose homeostasis and the development of insulin resistance
The relationship of the Diet Quality Index to prevalence of overweight in black and white adolescent girls: an examination of data from the National Heart, Lung, and …
On endothelial function in type 2 diabetic patients with coronary artery disease
Type 2 diabetes impairs interleukin-4 function in macrophages and amplifies the brain-based neuroimmune response
Insulin Signalling and Regulation of Protein kinase B in Adipocytes
Stress and Type 2 diabetes
Insulin Resistance
Pi 3-kinase and its up-and down-stream modulators as potential targets for the treatment of type II diabetes
The Selenium Significantly Activated the ER Stress Signaling Pathway in the Diabetes-Susceptible NOD Mice
Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease: the Diabetes Atherosclerosis Intervention …
Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation
Effect of Huanglian Jiedu Decoction on Glucose Transporter 4 Expression in Adipose and Skeletal Muscle Tissues of Insulin Resistant Rats.
Plasma arachidonic acid influences insulin-stimulated glucose uptake in healthy adult women
Mechanisms of cardiovascular complications in diabetes and potential new pharmacological therapies
Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids
Diabetes, inflammation, proinflammatory cytokines, and diabetic nephropathy
Future targets in the treatment of type 2 diabetes
Gene expression of 11β-hydroxysteroid dehydrogenase type 1 and type 2 in the kidneys of insulin-dependent diabetic rats
Long-term effects of recombinant human insulin-like growth factor I treatment on glucose and lipid metabolism and the growth of a patient with congenital generalized …
Inhibition of translation and insulin signaling by p21-activated protein kinase 2 (Pak2)
Oxidative stress induces insulin resistance by activating the nuclear factor-κB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3 …
Detecting type 2 diabetes by a single post-challenge blood sample
Insulin and cellular stress induced glucose uptake in 3T3-L1 adipoc tes
Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin-and AMPKα-independent manner
Ceramida como mediador de la resistencia a insulina producida por el factor de necrosis tumoral alfa en adipocitos marrones
Influence of calorie restriction on insulin signalling and glucose transport in skeletal muscle of rats
Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives
Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice
Childhood obesity
Predictors of chronic disease at midlife and beyond-the health risks of obesity
Food reward functions as affected by obesity and bariatric surgery
Inflammation in obesity-related diseases
Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet
Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation
Obesity and CKD: how to assess the risk?
Risks and management of obesity in pregnancy: current controversies
Brown adipose tissue and seasonal variation in humans
Vascular targeting of adipose tissue as an anti-obesity approach
Applying Brainpower to Obesity
Changes in adiposity status from childhood to adolescence: A 6-year longitudinal study in Portuguese boys and girls
Differential effects of calorie restriction and exercise on the adipose transcriptome in diet-induced obese mice
n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet
Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary‐induced obesity
Normalization of obesity-associated insulin resistance through immunotherapy
A putative role for apelin in the etiology of obesity
The effect of obesity on sperm disorders and male infertility
Prevention of obesity in preschool children
Response of fractional synthesis rate (FSR) of fibrinogen, concentration of D‐dimer and fibrinolytic balance to physical activity‐based intervention in obese …
Association between obesity and atopic dermatitis in childhood: a case-control study
Obesity-Induced Inflammation and Insulin Resistance
Obesity and Related Co-Morbid Conditions–A Retrograde Study
Changing the future of obesity: science, policy, and action
Adipokines in obesity
A potential role for insulin in management of the metabolic syndrome
“Liking” and “wanting” of sweet and oily food stimuli as affected by high-fat diet-induced obesity, weight loss, leptin, and genetic predisposition
Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration
Food deprivation-induced changes in body fat mobilization after neonatal monosodium glutamate treatment
Fibroblast growth factor 21 corrects obesity in mice
Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans
Inflammation and adipose tissue macrophages in lipodystrophic mice
Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet
Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells
Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high …
Insulin resistance, inflammation, and non-alcoholic fatty liver disease
A highly saturated fat-rich diet is more obesogenic than diets with lower saturated fat content
In vivo imaging of obesity-induced inflammation in adipose tissue
Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway
Weight regain after Roux-en-Y: a significant 20% complication related to PYY
Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress
Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta
Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice
High-fat diet-induced obesity in animal models
Mechanism for improved insulin sensitivity after gastric bypass surgery
Salsalate improves glycemia and inflammatory parameters in obese young adults
Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase–dependent pathway that is impaired with obesity
Adipose tissue as an endocrine organ
Berberine reverses free-fatty-acid-induced insulin resistance in 3T3-L1 adipocytes through targeting IKKβ
Adipose Tissue Secreted Factors in Specific Populations and Metabolic States: Implications for Energy Balance and Metabolic Health
REIN on obesity, proteinuria and CKD
Endoscopic solutions for weight loss
Obesity in children. Part 2: Prevention and management
Obesity surgery and gut–brain communication
Gastric bypass up-regulates insulin signaling pathway
Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
Angiogenesis and obesity
Diet-induced obesity alters protein synthesis: tissue-specific effects in fasted versus fed mice
Emerging role of adipose tissue hypoxia in obesity and insulin resistance
3 The Role of Obesity in
Childhood obesity: Treatment or prevention
Increased production of proinflammatory cytokines in adipose tissue of patients with end-stage renal disease
Oxidative stress and inflammation as therapeutic targets for high-fat diet-induced metabolic diseases
Bariatric surgery in young massively obese diabetic patients
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
Inflammatory links between obesity and metabolic disease
Inflammatory mechanisms in the regulation of insulin resistance
Inflammatory concepts of obesity
Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids
Adipokines: the missing link between insulin resistance and obesity
Insulin sensitivity: modulation by nutrients and inflammation
Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation*[S]
Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency
Obesity, adipogenesis and insulin resistance
Maternal obesity, inflammation, and fetal skeletal muscle development
Obesity: New Mechanisms and Translational Paradigms
Effects of rosiglitazone on intramyocellular lipid accumulation in Psammomys obesus
Endoscopic visceral fat removal as therapy for obesity and metabolic syndrome: a sham-controlled pilot study (with video)
Inflammation and insulin resistance
Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance
Studies on the anti-obesity activity of zinc-α2-glycoprotein in the rat
Is adipose tissue metabolically different at different sites?
Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity
PPAR γ is highly expressed in F4/80hi adipose tissue macrophages and dampens adipose-tissue inflammation
Maternal obesity promotes a proinflammatory signature in rat uterus and blastocyst
Deficiency of angiotensin type 2 receptor rescues obesity but not hypertension induced by overexpression of angiotensinogen in adipose tissue
n-3 PUFA: bioavailability and modulation of adipose tissue function: Symposium on ‘Frontiers in adipose tissue biology’
Overweight, obesity, and related diseases
Metabolic Mechanisms of Muscle Insulin Resistance
Pigment epithelium-derived factor contributes to insulin resistance in obesity
Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice
High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse
Obesity, inflammation, and atherosclerosis
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Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
45Obesity, insulin resistance and free fatty acids
Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
Adipokines in Obesity
TNF-α and adipocyte biology
Role of childhood obesity in atopic dermatitis
Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
Regulation of energy metabolism by inflammation: a feedback response in obesity and calorie restriction
c-Jun N-terminal kinase pathways in diabetes
The clinical implications of blood adiponectin in cardiometabolic disorders
Adipokine Signaling: Implications for Obesity
EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet–fed mice
Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
Food reward, hyperphagia, and obesity
Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases
Therapeutic approaches to target inflammation in type 2 diabetes
Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: involvement of antiadipogenic mechanism and extracellularly regulated …
Investigation of nuclear factor-κB inhibitors and interleukin-10 as regulators of inflammatory signalling in human adipocytes
Biomechanical promotion of mesenchymal stem cell proliferation as a countermeasure to the development of obesity and osteoporosis
Maternal obesity-impaired insulin signaling in sheep and induced lipid accumulation and fibrosis in skeletal muscle of offspring
Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice
Surgery for obesity
Integrating Role of Adipose Tissue Secretory Functions in Response to Dietary and Pharmacological Treatments
Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice
Obesity-Related Upregulation of Monocyte Chemotactic Factors in Adipocytes: Involvement of Nuclear Factor-κB and c-Jun NH2-Terminal Kinase Pathways
Tenomodulin gene and obesity-related phenotypes
Adiponectin levels in women with polycystic ovary syndrome: impact of metformin treatment in a randomized controlled study
Morphological and immunohistochemical features of brown adipocytes and preadipocytes in a case of human hibernoma
Analysis of the involvement of α2-AMPK in the beneficial effects of n-3 polyunsaturated fatty acids on obesity-associated metabolic derangements
Effect of aspirin on the expression of hepatocyte NF-κB and serum TNF-α in streptozotocin-induced type 2 diabetic rats
Angiogenesis and development of adipose tissue
siRNA-mediated reduction of inhibitor of Nuclear Factor-κB Kinase prevents Tumor Necrosis Factor-α–induced insulin resistance in human skeletal muscle
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
Obesity in neurobiology
Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress
Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses
Chemerin, a novel adipokine in the regulation of angiogenesis
The Association between Obesity, Cognition, and Visual Function
Tissular Tregs: A unique population of adipose-tissue-resident Foxp3+ CD4+ T cells that impacts organismal metabolism
Bariatric surgery to correct morbid obesity also ameliorates atherosclerosis in patients with type 2 diabetes mellitus
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models
Molecular mechanisms of obesity and diabetes: at the intersection of weight regulation, inflammation, and glucose homeostasis
Adipose inflammation: cause or consequence of obesity-related insulin resistance
Up-regulation of Toll-like receptor 4/nuclear factor-κB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese …
Intestinal microbiota during infancy and its implications for obesity
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
Large size cells in the visceral adipose depot predict insulin resistance in the canine model
Cardiac lipotoxic effects of obesity
Leptin is essential in maintaining normal vascular compliance independent of body weight
Low birth weight and markers of inflammation and endothelial activation in adulthood: the ARIC study
Hepatic insulin resistance, metabolic syndrome and cardiovascular disease
Inflammatory mediators and insulin resistance in obesity: role of nuclear receptor signaling in macrophages
Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis
The adipocyte as an endocrine cell
Brown adipose tissue in morbidly obese subjects
Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal …
Solidago chilensis Meyen hydroalcoholic extract reduces JNK/IκB pathway activation and ameliorates insulin resistance in diet-induced obesity mice
The Role of Obesity in Insulin Resistance: Epidemiological and Metabolic Aspects
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
The role of inflammatory cytokines in diabetes and its complications
Inflammatory lipid mediators in adipocyte function and obesity
Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of …
Early insulin sensitivity after restrictive bariatric surgery, inconsistency between HOMA-IR and steady-state plasma glucose levels
The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication
Assessment of adiponectin and leptin as biomarkers of positive metabolic outcomes after lifestyle intervention in overweight and obese children
Insulin-sensitizing effects of exercise on adiponectin and retinol-binding protein-4 concentrations in young and middle-aged women
Insulin resistance associated to obesity: the link TNF-alpha
Lycopene inhibits proinflammatory cytokine and chemokine expression in adipose tissue
Nature or nurture?: focus on “Preadipocyte transplantation: an in vivo study of direct leptin signaling on adipocyte morphogenesis and cell size”
The metabolic syndrome is associated with circulating adipokines in older adults across a wide range of adiposity
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Xanthones from mangosteen prevent lipopolysaccharide-mediated inflammation and insulin resistance in primary cultures of human adipocytes
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys
Hypoxia-inducible factor 1α induces fibrosis and insulin resistance in white adipose tissue
Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009
Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity
Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet–induced adipose tissue inflammation coincident with improved glucose homeostasis
Effects of systemic inflammation on insulin sensitivity in horses and inflammatory cytokine expression in adipose tissue
The multiple facets of the fat tissue
Lifestyle modification increases circulating adiponectin concentrations but does not change vaspin concentrations
Determinants of brown adipocyte development and thermogenesis
The protein kinase IKKɛ regulates energy balance in obese mice
Endoplasmic reticulum stress and inflammation in obesity and diabetes
Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRβ …
Bofutsushosan, an oriental herbal medicine, attenuates the weight gain of white adipose tissue and the increased size of adipocytes associated with the increase in …
Using gene expression signatures to dissect insulin resistance subtypes
Structure–effect relation of C18 long-chain fatty acids in the reduction of body weight in rats
Limited weight loss or simply no weight gain following lifestyle-only intervention tends to redistribute body fat, to decrease lipid concentrations, and to improve …
Effects of n-3 polyunsaturated fatty acids, rosiglitazone, low caloric diet and environmental pollutants: obesity and related disorders
Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet
Novel fat depot–specific mechanisms underlie resistance to visceral obesity and inflammation in 11β-hydroxysteroid dehydrogenase type 1–deficient mice
Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity
Type 2 diabetes as an inflammatory disease
Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium
Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue
Role of mitochondrial dysfunction in insulin resistance
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and β-cell dysfunction …
Genetic determinants and molecular pathways in the pathogenesis of Type 2 diabetes
Anthropometric indicators of obesity and their link to lifestyle and cardiovascular risk in Colorado firefighters
Adipokines in health and disease
Getting the message across: mechanisms of physiological cross talk by adipose tissue
Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe
Activation of peroxisome proliferator-activated receptor-δ by GW501516 prevents fatty acid-induced nuclear factor-κB activation and insulin resistance in skeletal …
Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK Action in a Fiber-Type Specific Manner
Polymethoxyflavones Activate Ca2+-Dependent Apoptotic Targets in Adipocytes
Adipose tissue development, structure and function
Increased whole-body and sustained liver cortisol regeneration by 11β-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for …
Uncoupling protein 1 expression and high-fat diets
Diet-induced obesity increases NF-κB signaling in reporter mice
Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats
Role of substance P in the regulation of glucose metabolism via insulin signaling-associated pathways
Vascular endothelial growth factor haplotypes associated with childhood obesity
Regulation by chronic-mild stress of glucocorticoids, monocyte chemoattractant protein-1 and adiposity in rats fed on a high-fat diet
Antidiabetic Properties of Zinc-α2-Glycoprotein in ob/ob Mice
Dissociation between skeletal muscle inhibitor-κB kinase/nuclear factor-κB pathway activity and insulin sensitivity in nondiabetic twins
The effect of aspirin on atherogenic diet‐induced diabetes mellitus
The obesity phenotype in children with asthma
Angiogenesis associated with visceral and subcutaneous adipose tissue in severe human obesity
Fighting fat with fat: the expanding field of adipose stem cells
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in …
Immune Modulation of Metabolism: The Role of Macrophages, NKT Cells and Dendritic Cells in the Development of the Metabolic Disturbances of Obesity
Oxidative stress and the etiology of insulin resistance and type 2 diabetes
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
The efficiency of cellular energy transduction and its implications for obesity
Transdifferentiation properties of adipocytes in the adipose organ
High-fat diet induces Ikkβ and reduces insulin sensitivity in rats with low running capacity
Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment
Central adiposity, systemic inflammation, and the metabolic syndrome
Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation
Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats
Obesity-Associated Inflammation And Its Role In Insulin Resistance
Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERα-deficient mice
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Inflammatory biomarkers associated with obesity and insulin resistance: a focus on lipocalin-2 and adipocyte fatty acid-binding protein
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Adipose tissue-targeted 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity
Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice
Pathogenic perspectives for the role of inflammation in diabetic nephropathy
IKKβ suppression of TSC1 function links the mTOR pathway with insulin resistance
Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention
Salsalate attenuates free fatty acid–induced microvascular and metabolic insulin resistance in humans
11-Beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors in type 2 diabetes mellitus and obesity
SPARC functions as an inhibitor of adipogenesis
Cellular Remodeling during the Growth of the Adipose Tissue
Adipose tissue macrophages: a piece of the PAI of metabolic syndrome
Substance P (SP)-neurokinin-1 receptor (NK-1R) alters adipose tissue responses to high-fat diet and insulin action
Inhibitory effect on protein kinase Cθ by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes
In vivo and in vitro application of black soybean peptides in the amelioration of endoplasmic reticulum stress and improvement of insulin resistance
IκB kinase ε: A potential therapeutic target for obesity (and nonalcoholic fatty liver disease)?
Dietary bitter melon seed increases peroxisome proliferator-activated receptor-γ gene expression in adipose tissue, down-regulates the nuclear factor-κB expression …
Therapeutic prospects of metabolically active brown adipose tissue in humans
14 The Link Between Esophageal Cancer and Morbid Obesity
Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
Rescuing 3T3-L1 adipocytes from insulin resistance induced by stimulation of Akt-mammalian target of rapamycin/p70 S6 kinase (S6K1) pathway and serine …
A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity
Development of obesity-induced inflammation and insulin resistance: The role of adipose tissue, fatty acids, and toll-like receptors
HSP and diabetes
Brown fat biology and thermogenesis
The role of the TWEAK/Fn14 signaling pathway in inflammatory and metabolic responses to diet-induced obesity
The presence and role of brown fat in adult humans
NATURE AND MECHANISMS OF INSULIN RESISTANCE–ROLE OF ADIPOKINES IN ETIOLOGY AND PATHOGENESIS
Transcriptional control of brown adipocyte development and physiological function—of mice and men
Fat Treg cells: a liaison between the immune and metabolic systems
Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight
Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects
Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse
The impact of myeloid cell-restricted insulin receptor deficiency on obesity-induced insulin resistance
Brown adipose tissue in humans is activated by elevated plasma catecholamines levels and is inversely related to central obesity
The relationship between patients’ serum glucose levels and metabolically active brown adipose tissue detected by PET/CT
The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress
THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue
A European evidence-based guideline for the prevention of type 2 diabetes
The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity
The cost-effectiveness of child obesity intervention
Maternal obesity induces sustained inflammation in both fetal and offspring large intestine of sheep
Chronic treatment with the cannabinoid 1 antagonist rimonabant altered vasoactive cyclo-oxygenase-derived products on arteries from obese Zucker rats
Aspirin use and risk of type 2 diabetes in apparently healthy men
Rein, tissu adipeux, adipocytes–quelles nouveautés?
Role of NF-κB in the pathogenesis of diabetes and its associated complications
Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology
The peroxide dilemma: opposing and mediating insulin action
Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure
Serum adiponectin levels are inversely correlated with insulin resistance in obese men with type 2 diabetes
Adipose tissue: development, anatomy and functions
Inflammation as a factor of the pathogenesis of insulin resistance and type 2 diabetes
Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits
Visfatin and adiponectin levels in children: relationships with physical activity and metabolic parameters
aging and Alzheimer’s disease through the biological mechanisms behind obesity and type II diabetes. May 2013 Health IN PRESS
TLR4 and insulin resistance
Obesity and Asthma
Fitness level and body composition are associated with inflammation in non-obese children
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells
The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study
SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes
SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins
Homocysteine upregulates resistin production from adipocytes in vivo and in vitro
A randomized trial of low-dose aspirin in the prevention of clinical type 2 diabetes in women
Gene expression profiles of diabetic mice treated with whole body hyperthermia: A high-density DNA microarray analysis
Role of the adipocyte-specific NF-κB activity in the regulation of IP-10 and T cell migration
Gut Microbes, Immunity, and Metabolism
Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice
The multi-systemic nature of diabetes mellitus: Genotype or phenotype?
Preliminary Studies Investigating a Potential Role of an Intestinal Bacterium in the Development of Diet-Induced Obesity
Muscle-specific IRS-1 Ser→ Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle
1 5 Insulin Resistance and Inhibitors of
The Role of Adipose Tissue Vasculature in Energy Balance.
Is there a relationship between insulin resistance and frailty syndrome?
Kupffer cell activation is a causal factor for hepatic insulin resistance
Gut decontamination with norfloxacin and ampicillin enhances insulin sensitivity in mice
Lipid induced overexpression of NF-κB in skeletal muscle cells is linked to insulin resistance
Potential role of salicylates in type 2 diabetes
Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate
The implication of brown adipose tissue for humans
To be or not to be fat: a novel role of Jak/Stat pathway in brown fat development and preventing obesity
The Role of Fatty Acids on Toll-like Receptor 4 Regulation of Substrate Metabolism with Obesity
The genetics of brown adipose tissue
Long-term effect of lifestyle intervention on adiposity, metabolic parameters, inflammation and physical fitness in obese children: a randomized controlled trial
Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes
Reversible physiological transdifferentiation in the adipose organ: symposium on ‘frontiers in adipose tissue biology’
Regulation of inducible nitric oxide synthase (iNOS) and its potential role in insulin resistance, diabetes and heart failure
Dog obesity, dog walking, and dog health
Effects of a structured exercise program on insulin resistance, inflammatory markers and physical fitness in obese Korean children
Adiponectin, leptin, the adiponectin/leptin ratio, and physical fitness in children and young adults
Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver?
Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet
Insulin resistance induced by tumor necrosis factor-α in myocytes and brown adipocytes
Salicylates increase insulin secretion in healthy obese subjects
Aerobic training reverses high-fat diet-induced pro-inflammatory signalling in rat skeletal muscle
Effect of the dietary fat quality on insulin sensitivity
Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism
Role of PPARγ in renoprotection in type 2 diabetes: molecular mechanisms and therapeutic potential
High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes
Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway
Altered estrogen receptor expression in skeletal muscle and adipose tissue of female rats fed a high-fat diet
Phosphorylation of IRS proteins, insulin action, and insulin resistance
15 Insulin Resistance and Inflammatory Signaling Pathways Modulated by High-Fat Diet
Macrophage infiltration and cytokine release in adipose tissue: angiogenesis or inflammation?
2009 World Congress on the Insulin Resistance Syndrome: Cardiovascular Disease Concepts
Adipose triglyceride lipase-null mice are resistant to high-fat diet–induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation
The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors
Ligands of Adipose Stem Cell Receptors Isolated by High-Throughput Combinatorial Peptide Library Screening
15 Insulin Resistance
Inflammatory signaling in skeletal muscle insulin resistance: green signal for nutritional intervention?
Activation of Fas (CD95) in adipocytes contributes to high fat diet-induced insulin-resistance
Molecular mechanisms of insulin resistance in chronic hepatitis C
Mathematical modeling of preadipocyte fate determination
Sleeve gastrectomy relieves steatohepatitis in high-fat-diet-induced obese rats
Inhibitors of 11β-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy
Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
NF-κB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance
Macrophage-conditioned medium inhibits adipocyte differentiation
Paradoxically high adiponectin in obese 16-year-old girls protects against appearance of the metabolic syndrome and its components seven years later
Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity
Downregulation of genes involved in NFκB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin …
Therapeutic potential of peroxisome proliferators–activated receptor-α/γ dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes
Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat
EFFECT OF ASPIRIN PRETREATMENT IN STREPTOZOTOCINE INDUCED TYPE-II DIABETIC RATS
Protective effect of aspirin in relation to IGF-1 in streptozotocin induced type-II diabetic rats
Plasma adiponectin does not correlate with insulin resistance and cardiometabolic variables in nondiabetic Asian Indian teenagers
Anti-obesity effects of resveratrol, black tea extract and caffeine in mice
CD40L induces inflammation and adipogenesis in adipose cells–a potential link between metabolic and cardiovascular disease
Adipose Tissue Biology: An Update Review
Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications
Nutrient regulation of energy metabolism in relation to obesity and type 2 diabetes
Berberine inhibits inflammatory response and ameliorates insulin resistance in hepatocytes
Body weight, plasma insulin, and coronary events with gemfibrozil in the Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT)
The immune response attenuates growth and nutrient storage in Drosophila by reducing insulin signaling
Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension
Neurodegeneration in an animal model of Parkinson’s disease is exacerbated by a high-fat diet
Reversible transdifferentiation in the adipose organ
Differential metabolic effects in white and brown adipose tissue by conjugated linoleic acid elicit lipodystrophy-associated hepatic insulin resistance
Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
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Tumor necrosis factor-like weak inducer of apoptosis attenuates the action of insulin in hepatocytes
Maternal obesity, inflammation and insulin resistance in skeletal muscle of fetal sheep
Vitamin C inhibits leptin secretion and some glucose/lipid metabolic pathways in primary rat adipocytes
SH2B1 regulates insulin sensitivity and glucose homeostasis by multiple mechanisms
Insulin induced phosphorylation of prohibitin at tyrosine114 recruits Shp1
Celecoxib attenuates liver steatosis and inflammation in non-alcoholic steatohepatitis induced by high-fat diet in rats
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
Lycopene prevents development of steatohepatitis in experimental nonalcoholic steatohepatitis model induced by high-fat diet
Diabetes and apoptosis: liver
Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes
Genetic characterization of the St. Kitts-origin vervet monkey (Chlorocebus aethiops ssp.) as a model of polygenic obesity
A Novel Role for Fetuin-A in the Pathophysiology of Glucocorticoid-Mediated Insulin Resistance
Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes
Age and sex differences in fat distribution in non-obese Japanese children
Role of inflammation in diabetic nephropathy
Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in rats
Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues
Perspective: chronic obstructive pulmonary disease and obesity: more than adipose tissue mass matters
Salsalate Efficacy in Blood Glucose Level Reduction in Diabetes
Association of visceral adiposity with increased intrarenal artery resistive index in HIV-1-infected patients receiving highly active antiretroviral therapy
Salicylate blocks lipolytic actions of tumor necrosis factor-α in primary rat adipocytes
Deposition Eliciting Insulin Resistance
A gene expression signature for insulin resistance
Effects of rosiglitazone and aspirin on experimental model of induced type 2 diabetes in rats: focus on insulin resistance and inflammatory markers
Altered nuclear factor-kappaB inducing kinase expression in insulin-resistant mice
Analysis of Main Proteins Associated with Lipid Droplets from Peri-Adrenal Adipose Tissue of Patients with Cushing’s Syndrome
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Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes
A central role for hepatocyte growth factor in adipose tissue angiogenesis
Antiobesity effect of allenic carotenoid, fucoxanthin
Transcriptional Control of Gene Expression in Different Adipose Tissue Depots
Local activation of the IκK-NF-κB pathway in muscle does not cause insulin resistance
Identification of a novel peptide ligand targeting visceral adipose tissue via transdermal route by in vivo phage display
LOX-1, oxidative stress and inflammation: a novel mechanism for diabetic cardiovascular complications
The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial
IFATS collection: Combinatorial peptides identify α5β1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells
Reactive oxygen species production is increased in the peripheral blood monocytes of obese patients
Extracellular high dosages of adenosine triphosphate induce inflammatory response and insulin resistance in rat adipocytes
Role of inhibitory κB kinase and c-Jun NH2-terminal kinase in the development of hepatic insulin resistance in critical illness diabetes
Role of inflammation and endothelial dysfunction of coronary arterioles in type 2 diabetes
Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis
Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes
Genetic Analysis of Adipose Lineage and Development
Stakeholder perceptions of the CHANGES weight management service
Prenatal hypoxia independent of undernutrition promotes molecular markers of insulin resistance in adult offspring
Bifurcation of in vivo hepatic energy metabolism and glucose production in insulin resistance and diabetes
Inhibition of the Nuclear Factor-κB Pathway Prevents Beta Cell Failure and Diet Induced Diabetes in Psammomys obesus
The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
Fish oil rich diet in comparison to saturated fat rich diet offered protection against lipopolysaccharide-induced inflammation and insulin resistance in mice
Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease
Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase
Enhanced glycogen metabolism in adipose tissue decreases triglyceride mobilization
Lessons in initiating insulin in clinical practice
An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells
Effects of exercise training and diet on lipid kinetics during free fatty acid-induced insulin resistance in older obese humans with impaired glucose tolerance
Reduction of hepatic CEACAM1 levels: an early mechanism of insulin resistance induced by high-fat diet
A new era for brown adipose tissue: New insights into brown adipocyte function and differentiation
Activation of Inflammatory pathways impairs insulin signaling in obese Zucker rat skeletal muscle
Metabolic Characterization of Human FOXC2 in Adipose Tissue
Studies examining the function of adipose tissue macrophages
Exercise and Type 2 Diabetes in Youth
Osteopontin knockout abates high fat diet-induced insulin resistance and adipose tissue inflammation
Aspirin and diabetes mellitus: revisiting an old player
High-fat feeding increases insulin receptor and IRS-1 coimmunoprecipitation with SOCS-3, IKKα/β phosphorylation and decreases PI-3 kinase activity in muscle
Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA
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Methodological and Clinical Studies on Insulin Resistance in Childhood
β3-Adrenergic Signaling Acutely Down Regulates Adipose Triglyceride Lipase in Brown Adipocytes
Effect of the dietary fat quality on insulin sensitivity
Therapeutic Strategies for the Treatment of Insulin Resistance in Various Metabolic Disease States
15 Exercise and Type 2 Diabetes in Youth
Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-α pathway activity in mice
Evidence for increased risk of prediabetes in the uremic patient
Biochemical Evaluation of Serum Adiponectin Level in Egyptian Breast Cancer Patients before and after Treatment
NF-κB activity in muscle from obese and type 2 diabetic subjects under basal and exercise-stimulated conditions
Leucine-induced Impairment of Insulin Sensitivity in Skeletal Muscle of Healthy Rats is Reversible
New Trends of Diabetes Therapy type II of the Animal Model
Objectively measured physical activity is negatively associated with plasma adiponectin levels in minority female youth
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Salicylates increase insulin secretion in healthy obese
Chronically Elevated Glucocorticoids in Conjunction with a High Fat Diet: A Model of Non Alcoholic Fatty Liver Disease
Molecular mechanisms of hepatic insulin resistance following injury
Distinct functions of autophagy kinases ULK1 and ULK2 in adipogenesis and adipocyte metabolism
Sweet heart–contributions of metabolism in the development of heart failure in diabetes mellitus
Chronic inflammation in the metabolic syndrome: emphasis on adipose tissue
Temporal Mechanisms by which a High Fat-diet Induces Skeletal Muscle Insulin Resistance
Insulin action
Oxidative stress in type 2 diabetes mellitus
The effect of high-dose sodium salicylate on chronically elevated plasma nonesterified fatty acid-induced insulin resistance and β-cell dysfunction in overweight and …
Role of the IKKβ/NF-κB inflammatory pathway, free fatty acids, and adiposity in insulin resistance in Hispanic Americans
Diabetes mellitus: metabolic effects and oxidative stress
Inflammation and NF-κB in Alzheimer’s disease and diabetes
Regulation of PGC-1 alpha in white adipose tissue by exercise
100 questions & answers about diabetes
Fatty acid-induced NF-κB activation and insulin resistance in skeletal muscle are chain length dependent
Association of the polymorphisms in the PSMA6 (rs1048990) and PSMB5 (rs2230087) genes with type 2 diabetes in Korean subjects
Overexpression of liver-specific cytochrome P4502E1 impairs hepatic insulin signaling in a transgenic mouse model of nonalcoholic fatty liver disease
Diabetic cardiomyopathy-to take a long story serious
Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria
Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1α and AMPKα
The effect of aspirin (ASA) given in cardiovascular therapeutic doses on glycemic control in type II diabetes
Proteomic Study of the Effect ofBerberine on the Adipose Tissue ofdb/db Mice and 3T3-L1 Adipocytes
The Relationship Between the Insulin Receptor Substrates and Metabolic Disease
Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats
Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
A study of non-alcoholic fatty liver disease (NAFLD) in South African patients and analysis of candidate genes in insulin resistance and fatty acid oxidation.
Elucidation of mechanisms of insulin resistance in human skeletal muscle
Molecular aspects of genetic predisposition to type 2 diabetes mellitus and its monogenic forms
Transcriptional responses of insulin resistance and mechanisms of drug action
Saturated fatty acid-induced NF-κB activation and insulin resistance in skeletal muscle are chain length dependent
Pro-inflammatory cytokines in Omani type 2 diabetic patients presenting anxiety and depression
Genetic predisposition to diabetic nephropathy
A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize …
Diabetische Kardiomyopathie–eine lang währende und ernstzunehmende Erkrankung
Regulation of Insulin and CHOP Gene Expression in Pancreatic Beta Cells
DOES ASPIRIN PRETREATMENT PREVENT DIABETES IN RATS?
Effect of early insulin therapy on nuclear factor κB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats
Depot-Specific Gene Expression Programs of Adipocytes: Physiological and Developmental Implications
Global IRS-1 phosphorylation analysis in insulin resistance
The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
The diabetogenic effects of excessive ethanol: reducing β-cell mass, decreasing phosphatidylinositol 3-kinase activity and GLUT-4 expression in rats
The unsolved problem of diabetes mellitus type 2 and associated complications
β-Arrestins: multifunctional signaling adaptors in type 2 diabetes
Insulin Action in Peripheral Glucose Uptake-The Molecular Perspective
Pilot randomized trial demonstrating reversal of obesity-related abnormalities in reward system responsivity to food cues with a behavioral intervention
Reversal of obesity-induced hypertriglyceridemia by (R)-α-lipoic acid in ZDF (fa/fa) rats
Partial reversal of obesity-induced insulin resistance owing to anti-inflammatory immunomodulatory potential of flaxseed oil
Brown adipose tissue thermogenesis in the resistance to and reversal of obesity: a potential new mechanism contributing to the metabolic benefits of proglucagon …
Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models
Dietary restriction reverses obesity-induced anhedonia
Reversal of obesity and metabolic disorders by exercise in high-fat diet-induced obese c57bl/6 mice
New pharmacological perspectives for the leptin receptor in the treatment of obesity
Metabolic Effects of n-3 PUFA as Phospholipids Are Superior to Triglycerides in Mice Fed a High-Fat Diet: Possible Role of Endocannabinoids
Animal models of dietary-induced obesity
IL-33 reverses an obesity-induced deficit in visceral adipose tissue ST2+ T regulatory cells and ameliorates adipose tissue inflammation and insulin resistance
Weight loss reversed obesity-induced HGF/c-Met pathway and basal-like breast cancer progression
Steps to Growing Up Healthy: a pediatric primary care based obesity prevention program for young children
Inhalation of carbon monoxide is ineffective as a long-term therapy to reduce obesity in mice fed a high fat diet
Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications
Hypothalamic gliosis associated with high-fat diet feeding is reversible in mice: a combined immunohistochemical and magnetic resonance imaging study
The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes
A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication
ATRIAL FIBRILLATION AND OBESITY: CHARACTERIZATION OF ELECTRO-STRUCTURAL ATRIAL SUBSTRATE WITH SUSTAINED OBESITY AND …
Exercise treatment of obesity
Chronic Treatment with Carbon Monoxide Releasing Molecule Reverses Dietary Induced Obesity in Mice
Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity
Atrial fibrillation and obesity: characterization of electro-structural atrial substrate with sustained obesity and reversal upon weight reduction.
Therapeutic assessment of cytochrome C for the prevention of obesity through endothelial cell-targeted nanoparticulate system
Role of obesity in the pathogenesis and progression of Barrett’s esophagus
Recombinant murine fibroblast growth factor 21 ameliorates obesity-related inflammation in monosodium glutamate-induced obesity rats
Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance
Resveratrol inhibits the deleterious effects of diet-induced obesity on thymic function
From abject eating to abject being: Representations of obesity in ‘Supersize vs. Superskinny’
Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice
Hepatic cannabinoid‐1 receptors mediate diet‐induced insulin resistance by increasing de novo synthesis of long‐chain ceramides
Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects
Pathophysiology of obesity-related renal dysfunction contributes to diabetic nephropathy
Abstract IA45: Obesity and the microenvironment in basal-like breast cancer
Physical exercise in overweight to obese individuals induces metabolic-and neurotrophic-related structural brain plasticity
Social Aspects as Maintenance Factors of the Obesity Condition: The Somatic Marker Hypothesis
Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice
Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation
APpEaLINg therapeutic target for obesity cardiomyopathy?
Animal Models for the Study of Human Disease: Chapter 13. Animal Models of Dietary-Induced Obesity
Immune regulation in obesity-associated adipose inflammation
The impact of cash transfers to poor women in Colombia on BMI and obesity: prospective cohort study
Prognosis of morbid obesity patients with advanced heart failure
Two contrasting outcomes of weight loss surgery: Positive impact on the heart, negative impact on the liver
DIEtAry CONtrOL Of OBESIty AND LAMINItIS rISk
Healthy Alberta Communities: Impact of a three-year community-based obesity and chronic disease prevention intervention
Leptin, a mediator of cardiac damage associated with obesity
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes
Role of Adiponectin in the Metabolic Effects of Cannabinoid Receptor-1 Blockade in Mice with Diet-Induced Obesity
Measuring success: a comparison of weight loss calculations
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Treatment of obesity as a potential complementary approach to cancer therapy
Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice
Browning of white adipose tissue by melatonin
A review on obesity and its management
Effects of an intensive short-term diet and exercise intervention: comparison between normal-weight and obese children
Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice
Cytokine profiling of young overweight and obese female African American adults with prediabetes
A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice
Chaperoning to the metabolic party: the emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes
Subcutaneous adipose tissue transplantation in diet‐induced obese mice attenuates metabolic dysregulation while removal exacerbates it
Cichoric acid reverses insulin resistance and suppresses inflammatory responses in the glucosamine-induced HepG2 cells
Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions
Curcumin promotes browning of white adipose tissue in a norepinephrine-dependent way
The complex and multifactorial relationship between testosterone deficiency (TD), obesity and vascular disease
Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting
Effects of metformin on weight loss: potential mechanisms
The neuropathology of obesity: insights from human disease
A role for sphingolipids in the pathophysiology of obesity-induced inflammation
Role of interleukins in obesity: implications for metabolic disease
Cardioprotective modulation of cardiac adiponectin and adiponectin receptors by omega-3 in the high-fat fed rats
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Influence of circular stapler diameter on postoperative stenosis after laparoscopic gastrojejunal anastomosis in morbid obesity
Insulin inhibits IL-10–mediated regulatory T cell function: implications for obesity
Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol
Diabetes and cancer: placing the association in perspective
Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation
Obesity and cholangiocarcinoma
The adipose organ at a glance
Pregnancy is a critical period for prevention of obesity and cardiometabolic risk
Insulin resistance and impaired adipogenesis
The brown fat secretome: metabolic functions beyond thermogenesis
Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control
HealthSTEPS: An Evidence-Based Program to Prevent Obesity and Related Diseases in Young Children
Adipose tissue inflammation in the pathogenesis of type 2 diabetes
Vascular-targeted nanotherapy for obesity: unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery
Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies
Effects of voluntary running on oxygen consumption, RQ, and energy expenditure during primary prevention of diet-induced obesity in C57BL/6N mice
Obesity and Weight Regulation
The bright-nights and dim-days of the urban photoperiod: implications for circadian rhythmicity, metabolism and obesity
Obesity, a health burden of a global nature
Physiotherapists’ perceptions of their role in the rehabilitation management of individuals with obesity
Fat cells directly sense temperature to activate thermogenesis
Mechanisms of insulin resistance in obesity
Vitamin C in the treatment and/or prevention of obesity
Inflammation-induced microvascular insulin resistance is an early event in diet-induced obesity
Metabolic heterogeneity of obesity: role of adipose tissue
Does chronic low-grade endotoxemia define susceptibility of obese humans to insulin resistance via dietary effects on gut microbiota?
Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance
Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1
Role of T cells in malnutrition and obesity
Causes and consequences of obesity: the contribution of recent twin studies
Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity
Constitutive activation of IKKβ in adipose tissue prevents diet-induced obesity in mice
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer’s disease
Maternal hyperglycemia during pregnancy predicts adiposity of the offspring
A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SD …
Bariatric surgery-effects on obesity and related co-morbidities
Decreased circulating levels of oxytocin in obesity and newly diagnosed type 2 diabetic patients
Human brown adipose tissue: what we have learned so far
Impact of abdominal obesity and ambulatory blood pressure in the diagnosis of left ventricular hypertrophy in never treated hypertensives
Age and obesity promote methylation and suppression of 5α-reductase 2: implications for personalized therapy of benign prostatic hyperplasia
Fibroblast growth factor-21 protects human skeletal muscle myotubes from palmitate-induced insulin resistance by inhibiting stress kinase and NF-κB
Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice
Mechanisms in endocrinology: white, brown and pink adipocytes: the extraordinary plasticity of the adipose organ
Oxidative stress and inflammation interactions in human obesity
High-fat load: mechanism (s) of insulin resistance in skeletal muscle
Recruitment of brown adipose tissue as a therapy for obesity-associated diseases
Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development
Metabolic inflammation: connecting obesity and insulin resistance
High-Fat Diet-Induced Obesity Exacerbates Inflammatory Bowel Disease in Genetically Susceptible Mdr1a−/− Male Mice
The impact of generation status on weight of immigrant and non-immigrant school-aged children living in minority situation: Preliminary results
Autophagy regulates inflammation in adipocytes
Populus balsamifera L.(Salicaceae) mitigates the development of obesity and improves insulin sensitivity in a diet-induced obese mouse model
Doxorubicin treatment inhibits PPARγ and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models
From farm to fat cell: why aren’t we all fat?
Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice
The combined effects of physical exercise training and detraining on adiponectin in overweight and obese children
The effect of exercise training in water on serum adiponectin and insulin resistance in obese children and adolescents
Obesity as a risk and severity factor in rheumatic diseases (autoimmune chronic inflammatory diseases)
Methods of a Multidisciplinary, Community-based Treatment Program for Overweight and Obese Preschoolers: A Family-Oriented, Healthy Eating, Activity, and …
Bacteria, viruses, and hypothalamic inflammation: Potential new players in obesity
Free Fatty Acids Induce Lhb mRNA but Suppress Fshb mRNA in Pituitary LβT2 Gonadotropes and Diet-Induced Obesity Reduces FSH Levels in Male Mice and …
Insulin and IGFs in obesity-related breast cancer
Recent advances in obesity-induced inflammation and insulin resistance
Targeting the IKKβ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer
Dichotomous effects of VEGF-A on adipose tissue dysfunction
Inflammation during obesity is not all bad: evidence from animal and human studies
Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after Roux-en-Y gastric bypass surgery in high-fat-fed obese rats
Endocrine changes in obesity
Peripheral targets in obesity treatment: a comprehensive update
Adipose tissue-related proteins locally associated with resolution of inflammation in obese mice
Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
Effectiveness of lifestyle interventions in child obesity: systematic review with meta-analysis
The By-Band study: gastric bypass or adjustable gastric band surgery to treat morbid obesity: study protocol for a multi-centre randomised controlled trial with …
Impact of wheat aleurone structure on metabolic disorders caused by a high-fat diet in mice
Obesity alters the gustatory perception of lipids in the mouse: plausible involvement of lingual CD36
White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
Obesity, but not ethanol, promotes tumor incidence and progression in a mouse model of hepatocellular carcinoma in vivo
Implication of inflammatory signaling pathways in obesity-induced insulin resistance
Aryl hydrocarbon receptor deficiency protects mice from diet-induced adiposity and metabolic disorders through increased energy expenditure
The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival
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Stromal progenitor cells from endogenous adipose tissue contribute to pericytes and adipocytes that populate the tumor microenvironment
BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response
The role of specific chaperons in pathogenesis of obesity and related diseases
Fas (CD 95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance
Influence of the core circadian gene “Clock” on obesity and leptin resistance in mice
Function and control of adipose tissue regulatory T cells: implications for obesity
Antiangiogenic nanotherapy for the control of obesity
Updates on gastric electrical stimulation to treat obesity: Systematic review and future perspectives
Protein tyrosine phosphatase 1B (PTP1B) and obesity
Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization
Inflammation, cytokines and insulin resistance: a clinical perspective
IKKβ links vascular inflammation to obesity and atherosclerosis
A ceramide-centric view of insulin resistance
Placental dysfunction in obese women and antenatal surveillance strategies
Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice
The whitening of brown fat and its implications for weight management in obesity
Role of saturated and polyunsaturated fat in obesity-related inflammation
Surgery for weight loss in adults
Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4
A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of …
Obesity, insulin resistance, and inflammaging
The beta-3 adrenergic agonist (CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice
Vascular rarefaction mediates whitening of brown fat in obesity
Does inflammation determine whether obesity is metabolically healthy or unhealthy? The aging perspective
Genetics and obesity
Two triterpeniods from Cyclocarya paliurus (Batal) Iljinsk (Juglandaceae) promote glucose uptake in 3T3-L1 adipocytes: The relationship to AMPK activation
Appetite and body weight regulation after bariatric surgery
White-to-brown metabolic conversion of human adipocytes by JAK inhibition
Connecting type 1 and type 2 diabetes through innate immunity
Intranasal insulin therapy for cognitive impairment and neurodegeneration: current state of the art
Presence of brown adipocytes in retroperitoneal fat from patients with benign adrenal tumors: relationship with outdoor temperature
Macrophage HIF-2α ameliorates adipose tissue inflammation and insulin resistance in obesity
Adipose tissue immunity and cancer
Avatars of Adipose Tissue–The Saga of Transformation of White Fat, the Villain into 3 Brown Fat, the Protector 4
Distinct time course of the decrease in hepatic AMP-activated protein kinase and Akt phosphorylation in mice fed a high fat diet
Reversion to a control balanced diet is able to restore body weight and to recover altered metabolic parameters in adult rats long-term fed on a cafeteria diet
Apparent histological changes of adipocytes after treatment with CL 316,243, a β-3-adrenergic receptor agonist
Inflammatory causes of obesity and metabolic diseases
Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in …
Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs life spans
Weighing in on adipocyte precursors
Sphingolipid metabolism and obesity-induced inflammation
Role of β-adrenergic receptors in the anti-obesity and anti-diabetic effects of zinc-α2-glycoprotien (ZAG)
Diabetes mellitus in dogs and its associated complications: A review
Obesity, inflammation, and insulin resistance
The adipose organ: white‐brown adipocyte plasticity and metabolic inflammation
Berberine activates thermogenesis in white and brown adipose tissue
Leucine signaling in the pathogenesis of type 2 diabetes and obesity
Effect of obesity on hepatic drug metabolism
Role of oxidative stress in endothelial insulin resistance
Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet
TGF-β/Smad3 signaling regulates brown adipocyte induction in white adipose tissue
B lymphocytes as emerging mediators of insulin resistance
Prospects of use of nutrient fiber, applying different feeding manners, to reduce obesity in dogs.
Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet
Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high‐fat‐diet …
Increased adipose tissue hypoxia and capacity for angiogenesis and inflammation in young diet-sensitive C57 mice compared with diet-resistant FVB mice
4β-Hydroxywithanolide E isolated from Physalis pruinosa calyx decreases inflammatory responses by inhibiting the NF-κB signaling in diabetic mouse adipose tissue
A2B Adenosine Receptors Prevent Insulin Resistance by Inhibiting Adipose Tissue Inflammation via Maintaining Alternative Macrophage Activation
Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice
MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16
Vascular Targeting of Adipose Tissue
Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary …
Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
Omega-3 phospholipids from fish suppress hepatic steatosis by integrated inhibition of biosynthetic pathways in dietary obese mice
Global correlation analysis for microRNA and gene expression profiles in human obesity
Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice
Fibrosis and adipose tissue dysfunction
Acute pancreatitis due to diabetes: the role of hyperglycaemia and insulin resistance
Targeted delivery using peptide-functionalised gold nanoparticles to white adipose tissues of obese rats
The regulation of muscle protein turnover in diabetes
Role of the adipocyte in metabolism and endocrine function
Brown adipose tissue: what have we learned since its recent identification in human adults
Endocrine and metabolic signaling in retroperitoneal white adipose tissue remodeling during cold acclimation
PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway
Effects of an in-patient treatment program based on regular exercise and a balanced diet on high molecular weight adiponectin, resistin levels, and insulin resistance …
Local macrophage proliferation in adipose tissue is a characteristic of obesity-associated inflammation: A dissertation
Food cue reactivity, obesity, and impulsivity: are they associated?
Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice
(−)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress
NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action
Adipocytokines in relation to cardiovascular disease
Metabolic adaptation of white adipose tissue to nutritional and environmental challenges
Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation
Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium
Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease
The role of chronic inflammation in obesity-associated cancers
Stromal cells derived from visceral and obese adipose tissue promote growth of ovarian cancers
Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances …
Celecoxib ameliorates non-alcoholic steatohepatitis in type 2 diabetic rats via suppression of the non-canonical Wnt signaling pathway expression
Brown and Beige Fat: Therapeutic Potential in Obesity
Oligopeptide complex for targeted non-viral gene delivery to adipocytes
Emerging role of JNK in insulin resistance
C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
Adipokines and cardiovascular risk in Cushing’s syndrome
Insulin resistance and atherosclerosis
Role of NKG2D in obesity-induced adipose tissue inflammation and insulin resistance
CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance
Type 2 Diabetes: Disease Overview
Circulating levels of IL-1B+ IL-6 cause ER stress and dysfunction in islets from prediabetic male mice
GLP-1 based therapeutics: simultaneously combating T2DM and obesity
Novel risk factors of cardiovascular disease and their associations between obesity, physical activity and physical fitness
Herbal and microbial products for the management of obesity
Adiponectin, resistin, and visfatin in childhood obesity and exercise
Nuclear factor κB–inducing kinase activation as a mechanism of pancreatic β cell failure in obesity
Insulin resistance
Development of an innovative drug delivery system targeted to adipose vessel utilizing novel nucleic acid aptamer for control of obesity
p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells
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TGF-B/Smad3 signaling regulates brown adipocyte induction in white adipose tissue
Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity
Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure
Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation
Reduction of insulin resistance and plasma glucose level by salsalate treatment in persons with prediabetes
Role of nuclear factor (erythroid-derived 2)-like 2 in metabolic homeostasis and insulin action: a novel opportunity for diabetes treatment?
The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis …
Metabolic inflexibility of white and brown adipose tissues in abnormal fatty acid partitioning of type 2 diabetes
Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by β3-Adrenergic Agonist: A Role for MicroRNAs
Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance
The expression of genes involved in NF-κB activation in peripheral blood mononuclear cells of patients with gestational diabetes
Obesity-related glomerulopathy and podocyte injury: a mini review
Metabolic syndrome, insulin resistance, and roles of inflammation–mechanisms and therapeutic targets
Molecular imaging of brown adipose tissue in health and disease
Ciliary neurotrophic factor (CNTF) protects non-obese Swiss mice against type 2 diabetes by increasing beta cell mass and reducing insulin clearance
Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats
Adipokine inflammation and insulin resistance: the role of glucose, lipids and endotoxin
Mechanisms of disease: role of neurotrophins in diabetes and diabetic neuropathy
Salsalate and adiponectin improve palmitate-induced insulin resistance via inhibition of selenoprotein P through the AMPK-FOXO1α pathway
Glucagon-like peptide 1 regulates adipogenesis in 3T3-L1 preadipocytes
Physical inactivity, insulin resistance, and the oxidative-inflammatory loop
Why does obesity increase the risk for cardiovascular disease?
Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring
Inflammatory markers in pediatric obesity: health and physical activity implications
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH)
Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis
Age impact on weight loss and glycolipid profile after laparoscopic sleeve gastrectomy: experience with 308 consecutive patients
Berries in Prevention of Metabolic Disease–focus on obesity, diabetes and gut microbiota
Astragalus Polysaccharide Improves Palmitate-Induced Insulin Resistance by Inhibiting PTP1B and NF-κB in C2C12 Myotubes
Obesity & the Workplace: Direct, Indirect Costs & the Role of Wellness Education
Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity
Influence of vitamin D treatment on transcriptional regulation of insulin-sensitive genes
Proteomic identification of target proteins of thiodigalactoside in white adipose tissue from diet-induced obese rats
Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo
Serum cytokine, chemokine and hormone levels in Saudi adults with pre-diabetes: a one-year prospective study
Oxidative stress in diabetes
Neural innervation of white adipose tissue and the control of lipolysis
Role of adipose cells in tumor microenvironment
Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?
The total phenolic fraction of Anemarrhena asphodeloides inhibits inflammation and reduces insulin resistance in adipocytes via regulation of AMP-kinase activity
Inactivation of NF-κB p65 (RelA) in liver improves insulin sensitivity and inhibits cAMP/PKA pathway
Interleukin-1 receptor antagonist: a new therapy for type 2 diabetes mellitus
T2D@ ZJU: a knowledgebase integrating heterogeneous connections associated with type 2 diabetes mellitus
KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression
Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity
Comparing physical activity programs for managing osteoarthritis in overweight or obese patients
Role of renin–angiotensin–aldosterone system in adipose tissue dysfunction
Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways
The Relationship Among Obesity, Inflammation, and Insulin Resistance
Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoids
Interactions between the gut, the brain and brown adipose tissue function
Anti diabetic effect of CL 316,243 (a β3-adrenergic agonist) by down regulation of tumour necrosis factor (TNF-α) expression
Linoleic and α-linolenic acid both prevent insulin resistance but have divergent impacts on 1 skeletal muscle mitochondrial bioenergetics in obese Zucker rats 2
Pathological role of adipose tissue dysfunction in cardio-metabolic disorders
Nutrigenomic Approaches to Understanding the Transcriptional and Metabolic Responses of Phytochemicals to Diet‐Induced Obesity and its Complications
Apoptotic pathways in adipose tissue
Adipokines and adipose tissue angiogenesis in obesity
Taking diabetes to heart—deregulation of myocardial lipid metabolism in diabetic cardiomyopathy
Cis-9, trans-11, trans-13-conjugated linolenic acid induces apoptosis and sustained ERK phosphorylation in 3T3-L1 preadipocytes
Type 2 diabetes: pathogenesis and natural history
Roles and tissue source of adiponectin involved in lifestyle modifications
The platform for adipose tissue expansion during positive energy balance
Brown adipose tissue harbors a distinct sub-population of regulatory T cells
Populus balsamifera Extract and Its Active Component Salicortin Reduce Obesity and Attenuate Insulin Resistance in a Diet-Induced Obese Mouse Model
CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
The Potential Epigenetic Modulation of Diabetes Influenced by Nutritional Exposures In Utero
Regulation of diet-induced adipose tissue and systemic inflammation by salicylates and pioglitazone
How brown is brown fat that we can see?
The Poisoning of Our Children: Fighting the Obesity Epidemic in America
Efficacy of commercial weight-loss programs: an updated systematic review
Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development
Do obese children have chronic inflammation & could this contribute to future CVD risk?
The influence of endotoxemia on the molecular mechanisms of insulin resistance
INFLUENCES ON TYPE 2 DIABETES AND OBESITY
Receptor for advanced glycation end products regulates adipocyte hypertrophy and insulin sensitivity in mice: involvement of Toll-like receptor 2
Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytes
Activated Kupffer cells inhibit insulin sensitivity in obese mice
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man
Two types of brown adipose tissue in humans
Epigenetic influences on type 2 diabetes and obesity
Extracellular signal-regulated protein kinase activation in spinal cord contributes to pain hypersensitivity in a mouse model of type 2 diabetes
Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice
Targeting inflammation in diabetes: Newer therapeutic options
Long-term effects of an inpatient weight-loss program in obese children and the role of genetic predisposition-rationale and design of the LOGIC-trial
Targeting inflammation using salsalate in patients with type 2 diabetes: effects on flow-mediated dilation (TINSAL-FMD)
Stem cells from adipose tissue and breast cancer: hype, risks and hope
Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats
Discrimination between brown and white adipose tissue using a 2-point Dixon water–fat separation method in simultaneous PET/MRI
Short term fat feeding rapidly increases plasma insulin but does not result in dyslipidaemia
Genetic deficiency of CD40 in mice exacerbates metabolic manifestations of diet-induced obesity: a dissertation
Energy metabolism in genetically fat and lean
The development mechanisms of overweight in young people
Duration of rise in free fatty acids determines salicylate’s effect on hepatic insulin sensitivity
Dietary ribonucleic acid suppresses inflammation of adipose tissue and improves glucose intolerance that is mediated by immune cells in C57BL/6 mice fed a high-fat …
Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared with normal birth weight
Bad Fat or Just More Fat? Murine Models of Metabolically Healthy Obesity
Dietary supplementation with evodiamine prevents obesity and improves insulin resistance in ageing mice
Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese …
Growth hormone (GH) differentially regulates NF-kB activity in preadipocytes and macrophages: implications for GH’s role in adipose tissue homeostasis in obesity
Burn induces browning of the subcutaneous white adipose tissue in mice and humans
Role of macrophages in exercise-induced enhancement of insulin sensitivity in skeletal muscle
Turning off a viral/lipid sensor improves type 2 diabetes
Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia
Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females
Correlated increase of omentin-1 and adiponectin by exenatide, avandamet and dietary change in diet-induced obese rats
Adipocyte-specific IKKβ signaling suppresses adipose tissue inflammation through an IL-13-dependent paracrine feedback pathway
Fitness and adiposity are independently associated with cardiometabolic risk in youth
Advances in an active and passive targeting to tumor and adipose tissues
Adipose tissue biglycan as a potential anti-inflammatory target of sodium salicylate in mice fed a high fat diet
Flavanone naringenin: An effective antihyperglycemic and antihyperlipidemic nutraceutical agent on high fat diet fed streptozotocin induced type 2 diabetic rats
PI3K/AKT pathway in modulating glucose homeostasis and its alteration in diabetes
Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus
PEDF-induced alteration of metabolism leading to insulin resistance
Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance
Spice up your life: adipose tissue and inflammation
ER stress in adipocytes and insulin resistance: Mechanisms and significance
Salicylate acutely stimulates 5′-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscles
Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele
Insulin Resistance-ECAB
Metabolic Control by Inflammation and Immunity: Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity
Compliance for Lifestyle Modification among Obese/Overweight School Children from 7-12 Years
Mice deficient in proglucagon-derived peptides exhibit glucose intolerance on a high-fat diet but are resistant to obesity
Targeting inflammation in the treatment of type 2 diabetes: time to start
Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue
Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis
Inflammation and oxidative stress in diabetic nephropathy: new insights on its inhibition as new therapeutic targets
A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase
High-protein diets alters body composition and improves insulin resistance in a rat model of low birth weight
Novel aspects of metabolic regulation and inflammation in human adipocytes
Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations
Modulation of the Wnt/β-Catenin Pathway in Obesity: A Role for Bile Acid Metabolic Improvement
Manipulation of the gut microbiota in C57BL/6 mice changes glucose tolerance without affecting weight development and gut mucosal immunity
Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction
The browning of white adipose tissue: some burning issues
Lifestyle modification decreases arterial stiffness in overweight and obese men: dietary modification vs. exercise training
Effect of estrogen on expression of prohibitin in white adipose tissue and liver of diet-induced obese rats
Adipose tissue macrophages in obesity, inflammation, and cancer
The Genetic Mechanisms Underlying Human Obesity
Enhanced prereceptor glucocorticoid metabolism and lipogenesis impair insulin signaling in the liver of fructose-fed rats
20 Adipose Drug Targets
IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade
2, 4-dinitrophenol downregulates genes for diabetes and fatty liver in obese mice
Effects of DAPT on Serum Vascular Endothelial Growth Factor and Its Soluble Receptor in Obese BALB/C Mice.
Insulin resistance and atherosclerosis
Docosahexaenoic acid supplementation improved lipocentric but not glucocentric markers of insulin sensitivity in hypertriglyceridemic men
AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P …
Metabolic characteristics and therapeutic potential of brown and? beige? adipose tissues
The role of CREB in the liver and adipose tissue
Molecular aspects of glucose homeostasis in skeletal muscle–A focus on the molecular mechanisms of insulin resistance
Adipose Tissue-derived progenitor cells and cancer
Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing …
Effect of six-month lifestyle intervention on adiponectin, resistin and soluble tumor necrosis factor-α receptors in obese adolescents
Physiology & pathophysiology of human brown adipose tissue
Selection of aptamers specific for adipose tissue
Salicylic acid: old and new implications for the treatment of type 2 diabetes?
n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet
Bcl10 links saturated fat overnutrition with hepatocellular NF-κB activation and insulin resistance
The roles of diet and SirT3 levels in mediating signaling network changes in insulin resistance
Avatars of adipose tissue: the saga of transformation of white fat, the villain into brown fat, the protector. Focus on “Inflammation induced by RAW macrophages …
CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action
Oligopeptide complex for targeted non-viral gene delivery to adipocytes
Dual actions of a novel bifunctional compound to lower glucose in mice with diet-2 induced insulin resistance 3
Effects of interventions on adiponectin and adiponectin receptors
Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity …
Nutritional modulation of insulin resistance
Targeting inflammation through a physical active lifestyle and pharmaceuticals for the treatment of type 2 diabetes
Erythropoietin inhibits gluconeogenesis and inflammation in the liver and improves glucose intolerance in high-fat diet-fed mice
Best practice dietetic management of overweight and obese children and adolescents: a 2010 update of a systematic review
A randomised trial of salsalate for insulin resistance and cardiovascular risk factors in persons with abnormal glucose tolerance
Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance
Low level of trans-10, cis-12 conjugated linoleic acid decreases adiposity and increases browning independent of inflammatory signaling in overweight Sv129 mice
Influences of the diabetes surgery on pancreatic B-cells mass
Type 2 diabetes mellitus: etiology, pathogenesis, and natural history
Increased Adiposity and Colorectal Cancer
Novel anti-diabetic effect of SCM-198 via inhibiting the hepatic NF-κB pathway in db/db mice
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
Linking mitochondrial bioenergetics to insulin resistance via redox biology
Modified Si-Miao-San inhibits inflammation and promotes glucose disposal in adipocytes through regulation of AMP-kinase
Browning of Adipose Organ
Research Article Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation
Pharmacogenomics of cardiovascular complications in diabetes and obesity
The effect of salsalate on biochemical factors and endothelial dysfunction of prediabetic patients: A randomized clinical trial
Anti-obesity mechanisms of conjugated linoleic acid (CLA): Role of inflammatory signaling and browning in white adipose tissue
Antihyperglycemic effect of carvacrol in combination with rosiglitazone in high-fat diet-induced type 2 diabetic C57BL/6J mice
Regulation of Adipose Tissue Function and Metabolic Homeostasis.
Nerium oleander distillate improves fat and glucose metabolism in high-fat diet-fed streptozotocin-induced diabetic rats
Does 8 weeks of strenuous bicycle exercise improve diabetes-related inflammatory cytokines and free fatty acids in type 2 diabetes patients and individuals at high …
Effect of diclofenac on plasma glucose level, insulin resistance, inflammatory markers and hepatocytes in diabetic albino rats
Effectivity Combination of Bitter Melon (Momordica charantia) and Bitter (Andrographis paniculata) Extract to Suppress Proinflammatory Cytokines in Diabetic Mouse …
Effect of melatonin on obesity, low-grade inflamation and oxidative stress in diabetic fatty (ZDF) rats
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice
Heterozygous rho kinase2 deficinecy increases whole body insulin sensitivity in mice
Aspirin-induced inhibition of adipogenesis was p53-dependent and associated with inactivation of pentose phosphate pathway
Overweight in the military: causes and effects
Normalization of fasting hyperglycemia is beneficial for successful introduction of small amount of the GLP-1 analog liraglutide in an obese patient with type 2 diabetes …
An Approach to Obesity as a Cardiometabolic Disease: Potential Implications for Clinical Practice
Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes
Novel link between inflammation, endothelial dysfunction, and muscle insulin resistance
Regulation of Fluid-phase Uptake in Podocytes by Albumin-associated Lipids and Role of NKG2D in Obesity-induced Adipose Tissue Inflammation and …
Opposite effects of quercetin, luteolin, and epigallocatechin gallate on insulin sensitivity under normal and inflammatory conditions in mice
The effects of stearidonic acid on 3T3-L1 adipocytes
Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity
Toll-like receptor 4 knockout mice are protected against endoplasmic reticulum stress induced by a high-fat diet
Insulin resistance, metabolic stress, and atherosclerosis
Understanding the regulation of adipogenesis and adipocyte metabolism in obesity
The adipose organ: morphological perspectives of adipose tissues
An intimate relationship between ROS and insulin signalling: implications for antioxidant treatment of fatty liver disease
PPARγ as a therapeutic target in diabetic nephropathy and other renal diseases
Correlation of Non-alcoholic Fatty Liver Disease and Diabetes Mellitus
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Effects of exercise and elevated fatty acid availability on muscle lipid metabolism and insulin sensitivity
A peptide probe for targeted brown adipose tissue imaging
Effect of salsalate on insulin action, secretion, and clearance in nondiabetic, insulin-resistant individuals: a randomized, placebo-controlled study
Insulin Sensitivity in Valproate Treated Epileptics.
Salsalate improves glycemic control in patients with newly diagnosed type 2 diabetes
Heme Oxygenase 1 in Hepatocytes Drives Insulin Resistance in Mice and Men
Effect of natural compounds on insulin signaling
Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment
Response to comment on “a peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys”
Effect of medical nutrition therapy on outcomes of patients with pre-diabetes in a rural Nebraska primary care clinic: A pilot study
Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance
Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial
Expression of “brown-in-white” adipocyte biomarkers shows gender differences and the influence of early dietary exposure
Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice
Identification of novel regulators of mesenchymal stem cell commitment to the brown adipocyte lineage
Enhanced glucose tolerance and pancreatic beta cell function by low dose aspirin in hyperglycemic insulin-resistant type 2 diabetic Goto-Kakizaki (GK) rats
The effects of exercise-induced weight loss on ratio of acylated and unacylated ghrelin in obese adolescents
Technological discipline, obese bodies and gender: A sociological analysis of gastric banding surgery
Influence of feeding a fish oil-containing diet to young, lean, adult dogs: effects on lipid metabolites, postprandial glycaemia and body weight
Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance
Influencia de la cirugía de diabetes sobre la masa de células beta pancreáticas
Origin of White and Brown Adipose Cells From Vascular Endothelium: A Dissertation
Evaluation of the CHANGES weight management programme: Prospective Patients
Air pollution as a risk factor for type 2 diabetes
From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates
Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: a randomized controlled trial
An update on the pathogenesis of type 2 diabetes mellitus
Sodium salicylate treatment in early lactation increases whole-lactation milk and milk fat yield in mature dairy cows
Using RNA-seq technology to explore the impact of growth hormone on angiogenesis and other cellular pathways in subcutaneous and epididymal adipose tissue …
Pathogenesis of type 2 diabetes mellitus
Adipose tissue dysfunction and inflammation in cardiovascular
BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy
An ERP investigation of food cue responsivity in non-obese, weight gain prone individuals
High density lipoprotein is positively correlated with the changes in circulating total adiponectin and high molecular weight adiponectin during dietary and fenofibrate …
THE ROLE OF CGI-58/ABHD5 IN LIPID METABOLISM, INFLAMMATION, AND INSULIN ACTION
Examining physiological roles of adipose derived VEGF: Consequences in substrate availability and endurance exercise capacity in adipocyte specific VEGF …
Vascularization in Engineered Adipose Tissue
The culture and differentiation of human pluripotent cells into brown and white adipocytes
Lack of Association of Insulin Receptor Substrate Gene Polymorphisms with Obstructive Sleep Apnea Syndrome
Inhibition of the IKK pathway restores PI3-K activity in high-fat fed rodent skeletal muscles
Role of NF-Kappa B (NF-κB) in diabetes
Isoenergetic feeding of low carbohydrate-high fat diets does not increase brown adipose tissue thermogenic capacity in rats
Lasting Effects on Body Weight and Mammary Gland Gene Expression in Female Mice upon Early Life Exposure to n-3 but Not n-6 High-Fat Diets
THE MECHANISMS OF INSULIN ACTION
Adipose tissue engineering: Obesity disease model and soft tissue regeneration
Unravelling the link between insulin resistance and androgen excess
Hepatic expression of constitutively active IKKβ in mice induces low-grade inflammation, but does not cause insulin resistance: a protective role for A20?
13 Obesity and Diabetes
The effect of endurance and resistance training on adiponectin in sedentary young woman
AMPK activators as a drug for diabetes, cancer and cardiovascular disease
On the horizon: new oral therapies for type 2 diabetes mellitus
Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells
Mechanisms Mediating Antidiabetic Effects of Serviceberry extracts, Curcumin, and Stilbenes
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Loss of adipocyte VEGF impairs endurance exercise capacity in mice
A critical appraisal of brown adipose tissue metabolism in humans
Gene expression of sternohyoid and diaphragm muscles in type 2 diabetic rats
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High fat diet increases tumor incidence in the intestine due to alterations in microbial communities and immune system
Insulin-and growth factor-resistance impairs vascular regeneration in diabetes mellitus
On the horizon: New oral therapies for type 2 diabetes mellitus
Bone mineral density is associated with total body weight loss ten years after Roux-en-Y gastric bypass
Do anti-angiogenic cancer therapies increase risk of significant weight loss?
Pathogenesis of diabetes-tuberculosis comorbidity, The
Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response
ß-cell reserve in insulin resistant pregnant mice
Research Article Nerium oleander Distillate Improves Fat and Glucose Metabolism in High-Fat Diet-Fed Streptozotocin-Induced Diabetic Rats
Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet
Periodontitis modulates insulin signaling, c-Jun N-terminal kinase activity, IKK activity, and insulin receptor substrate-1 ser 307 phosphorylation in muscle and …
Cellular plasticity in white adipose tissue: in vivo identification of bipotent adipocyte progenitors in adult white adipose tissue
Effects of Exercise and Diet-Induced Weight Loss in Overweight/Obese Women on Characterization of Serum/White Blood Cells, microRNAs and Cytokine Gene …
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Insulin plant (Costus pictus) extract improves insulin sensitivity and ameliorates atherogenic dyslipidaemia in fructose induced insulin resistant rats: Molecular …
CHANGES Weight Management Service Evaluation
Studies Defining The Local Function of Adipose Tissue IGF1 And The Role of Lipolysis in Adipose Tissue Macrophage Lipid Uptake
Modified Si-Miao-San () regulates adipokine expression and ameliorates insulin resistance by targeting IKKβ/Insulin receptor substrate-1 in mice.
The interrelationship between insulin resistane and Alzheimer development
Factors of Inflammation in Haitian Americans and African Americans with and without Type 2 Diabetes
Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding …
Diabetes prevention education aimed at Dutch and Turkish relatives at risk: Development and evaluation of DiAlert
Identification of the NF-κB inhibitor A20 as a key regulator for human adipogenesis
Regulation of hepatic insulin receptor activity following injury
A meta-analysis of salicylates for type 2 diabetes mellitus
Resveratrol and Metformin Combination Therapy in Prevention and Treatment of Insulin Resistance
Impact of Co-Administration of Salicylic Acid with Glibenclamide in a Rat Model of Type 2 Diabetes Mellitus
Effects of Amino Acids on the Regulation of Insulin Sensitivity in Skeletal Muscle Cells
Crosstalk between insulin and Toll-like receptor signaling pathways in the central nervous system
Peptides as targeting probes against tumor vasculature for diagnosis and drug delivery
The Effects of Salsalate on Biochemical Factors of Serum and Endothelial Dysfunction in Patients with Newly Diagnosed Type 2 Diabetes
Novel players in rescue of β-cells from inflammation-mediated destruction in Type 2 Diabetes Mellitus
Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase a …
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Alteration in lymphocyte population and humoral immune response in type 2 diabetic Goto–Kakizaki rats
Rosiglitazone inhibits hepatic insulin resistance induced by chronic pancreatitis and IKK-β/NF-κB expression in liver
prevents vascular endothelial dysfunction in a type 2 diabetic rat model
High dose of aspirin moderates diabetes-induced changes of heart glycogen/glucose metabolism in rats
Insulin transcytosis across adipose microvascular endothelial cells: Mechanism and physiological implications
Reversal of obesity-driven aggressiveness of endometrial cancer by metformin
Reversal of obesity and liver steatosis in mice via inhibition of aryl hydrocarbon receptor and altered gene expression of CYP1B1, PPARα, SCD1, and osteopontin
Adipose tissue supports normalization of macrophage and liver lipid handling in obesity reversal
Obesity-related perivascular adipose tissue damage is reversed by sustained weight loss in the rat
Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse …
Reversal of obesity: The quest for the optimum dietary regimen
Nanotechnology advances towards development of targeted-treatment for obesity
Inhibiting glycogen synthase kinase 3 reverses obesity-induced white adipose tissue inflammation by regulating apoptosis inhibitor of macrophage/CD5L-mediated …
Short chain fatty acids in the colon and peripheral tissues: a focus on butyrate, colon cancer, obesity and insulin resistance
Reversal of obesity-driven aggressiveness of endometrial cancer by metformin
Resveratrol reverses the adverse effects of a diet-induced obese murine model on oocyte quality and zona pellucida softening
Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through growth differentiation factor 3
Obesity-related epigenetic changes after bariatric surgery
Blood-brain barriers in obesity
To be or not to be obese: Impact of obesity on lymphatic function
Anti-obesity and insulin-sensitising effects of a glycosaminoglycan mix
SUN-543 Real World Evidence of Successful Weight Management for the Obese Population: Complete Reversal of Obesity Related Metabolic Co-Morbidities …
Simvastatin has anti-tumorigenic effects in endometrial cancer via reversal of obesity-driven upregulation of lipid biosynthesis
Attenuation of Obesity, Hepatic Steatosis and Reversal of Atherosclerosis by the Flavonoids Naringenin and Nobiletin
Mild suppression of hyperinsulinemia to treat obesity and insulin resistance
Vascular targeted nanotherapeutic approach for obesity treatment
Dietary options for rodents in the study of obesity
Role of innate and adaptive immunity in obesity-associated metabolic disease
Dynamic energy balance and obesity prevention
Caloric restriction recovers impaired β-cell-β-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice
Genetics of obesity: can an old dog teach us new tricks?
Milestone weight loss goals (weight normalization and remission of obesity) after gastric bypass surgery: long-term results from the University of Michigan
Obesity and breast cancer–what’s new?
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Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity‐induced chronic kidney disease
Hypothalamic Pomc‐deficiency Impairs the Function of Leptin to Decrease Food Intake and Bodyweight
How does exercise support dietary approaches to weight loss and better health?
Comment on: Five-year changes in dietary intake and body composition in adolescents with severe obesity undergoing laparoscopic Roux-en-Y gastric bypass …
Long-term remission of type 2 diabetes—two roads to the elusive goal
Naltrexone/bupropion for the treatment of obesity and obesity with Type 2 diabetes
Dietary management of obesity: a review of the evidence
Studies of perivascular adipose tissue function in obesity and following diet-induced weight loss
The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed?
Evidence-Based Guidelines for the Treatment of Obesity
Animal models of obesity and diabetes mellitus
Appetite control with relevance to mitochondrial biogenesis and activation of post-prandial lipid metabolism in obesity linked diabetes
Effect of obesity on bladder cancer and renal cell carcinoma incidence and survival
The effects of bariatric surgery on gut microbiota in patients with obesity: a review of the literature
Whole-Food Plant-Based Lifestyle Program and Decreased Obesity: A 10-Year Follow-up
Comprehensive molecular characterization of surgical vs. dietary weight loss: impact on mammary tumor burden
Promises of nanotherapeutics in obesity
Bilobalide abates inflammation, insulin resistance and secretion of angiogenic factors induced by hypoxia in 3T3-L1 adipocytes by controlling NF-κB and JNK …
The possible factors affecting microglial activation in cases of obesity with cognitive dysfunction
Vascular risk reduction in obesity through reduced granulocyte burden and improved angiogenic monocyte content following bariatric surgery
Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes
Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice
Caloric Restriction recovers impaired β-cell-β-cell coupling, calcium oscillation coordination and insulin secretion in prediabetic mice
Targeting IκB kinase β in adipocyte lineage cells for treatment of obesity and metabolic dysfunctions
Profound and redundant functions of arcuate neurons in obesity development
Angiogenesis in obesity
Understanding human physiological limitations and societal pressures in favor of overeating helps to avoid obesity
Obesity in older people: A new scenario and a new challenger
Potential role of aryl hydrocarbon receptor signaling in childhood obesity
Childhood obesity plans already show progress, minister claims
Long-term exercise-secreted extracellular vesicles promote browning of white adipocytes by suppressing miR-191a-5p
Gastric bypass surgery in lean adolescent mice prevents diet-induced obesity later in life
Dietary nitrite reverses features of postmenopausal metabolic syndrome induced by high-fat diet and ovariectomy in mice
Dibenzazepine-loaded nanoparticles induce local browning of white adipose tissue to counteract obesity
Sleeve gastrectomy reversed obesity-induced hypogonadism in a rat model by regulating inflammatory responses in the hypothalamus and testis
Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors
TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl) purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway
Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet
Differential effects of diet and weight on taste responses in diet‐induced obese mice
Potential relationship between dietary long-chain saturated fatty acids and hypothalamic dysfunction in obesity
Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles
Perioperative course, weight loss and resolution of comorbidities after primary sleeve gastrectomy for morbid obesity: are there differences between adolescents and …
Prohibitin–At the crossroads of obesity-linked diabetes and cancer
THE PERCEPTION OF PHYSIOTHERAPISTS OF KARACHI IN THEIR ROLE TO REHABILITATE AND MANAGE OBESITY
Resolution of refractory iron deficiency anemia following sleeve gastrectomy in an adolescent with severe obesity
Persistent microbiome alterations modulate the rate of post-dieting weight regain
Legend of weight loss: a crosstalk between the bariatric surgery and the brain
Zfp423 maintains white adipocyte identity through suppression of the beige cell thermogenic gene program
Trained immunity: linking obesity and cardiovascular disease across the life-course?
Long-term atorvastatin or the combination of atorvastatin and nicotinamide ameliorate insulin resistance and left ventricular diastolic dysfunction in a murine model of …
Exploring the impact of obesity on skeletal muscle function in older age
An eclectic cast of cellular actors orchestrates innate immune responses in the mechanisms driving obesity and metabolic perturbation
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
Obesity and metabolic health status are determinants for the clinical expression of hypertrophic cardiomyopathy
Beiging of white adipose tissue as a therapeutic strategy for weight loss in humans
Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance
Obesity, body weight regulation and the brain: insights from fMRI
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Gut microbiota modulation and its relationship with obesity using prebiotic fibers and probiotics: a review
The correlation between cardiorespiratory fatigue and lower extremity joint moments in obese individuals and the associated reverse causation
Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero
Downward trends in the prevalence of childhood overweight in two pilot towns taking part in the VIASANO community‐based programme in B elgium: data from a …
DNA methylation changes more slowly than physiological states in response to weight loss in genetically diverse mouse strains
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The Effects of Diet Induced Obesity and Metabolic Irregularities on Hippocampal-Based Cognition and Neuroplasticity in Young Female and Male Rat
Turning the tables on obesity: young people, IT and social movements
Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue
Skeletal muscle inflammation and insulin resistance in obesity
New therapeutic approaches for the treatment of obesity
Transcriptional dysregulation of adipose tissue autophagy in obesity
Deletion of the glutaredoxin-2 gene protects mice from diet-induced weight gain, which correlates with increased mitochondrial respiration and proton leaks in skeletal …
Exercise, adipokines and pediatric obesity: a meta-analysis of randomized controlled trials
Pharmacotherapy of obesity: limits and perspectives
The role of WIC in obesity prevention
Neutrophil elastase regulates emergency myelopoiesis preceding systemic inflammation in diet-induced obesity
Obesity in adolescents and youth: the case for and against bariatric surgery
Association between exercise and treatment with liraglutide in obese rats by cafeteria diet
Adipose tissue heterogeneity-development and application of nonlinear microscopy methods
Obesity prevention in a city state: lessons from New York City during the Bloomberg Administration
Link between chemerin, central obesity, and parameters of the Metabolic Syndrome: findings from a longitudinal study in obese children participating in a lifestyle …
Obesity and associated comorbidities in people and companion animals: a one health perspective
An Extract of Russian Tarragon Prevents Obesity‐Related Ectopic Lipid Accumulation
Transgenerational epigenetics, paternal obesity, and insulin resistance
Post-dieting weight gain: the role of persistent microbiome changes
Vascular endothelial regulation of obesity-associated insulin resistance
Selective activation of Gs signaling in adipocytes causes striking metabolic improvements in mice
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Prohibitin: A new player in immunometabolism and in linking obesity and inflammation with cancer
How do structurally distinct compounds exert functionally identical effects in combating obesity?
Peptide-functionalized quantum dots for potential applications in the imaging and treatment of obesity
Targeted proapoptotic peptides depleting adipose stromal cells inhibit tumor growth
A systematic review of studies of DNA methylation in the context of a weight loss intervention
Targeting ceramide metabolism in obesity
Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes
Food for thought: reward mechanisms and hedonic overeating in obesity
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages
The gut microbiome, obesity, and weight control in women’s reproductive health
Carotenoids and carotenoid conversion products in adipose tissue biology and obesity: Pre-clinical and human studies
A transcriptomic analysis reveals novel patterns of gene expression during 3T3-L1 adipocyte differentiation
Effect of resveratrol on adipokines and myokines involved in fat browning: Perspectives in healthy weight against obesity
Visceral adipose tissue macrophage-targeted TACE silencing to treat obesity-induced type 2 diabetes
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Food cues and obesity: overpowering hormones and energy balance regulation
The role of the Nrf2 signaling in obesity and insulin resistance
Activation of neuregulin-4 in adipocytes improves metabolic health by enhancing adipose tissue angiogenesis
Mouse modeling of obese lung disease. Insights and caveats
Steroid metabolomic signature of insulin resistance in childhood obesity
PDGFRβ regulates adipose tissue expansion and glucose metabolism via vascular remodeling in diet-induced obesity
Microbial medicine: prebiotic and probiotic functional foods to target obesity and metabolic syndrome
P62 plasmid can alleviate diet-induced obesity and metabolic dysfunctions
Brown adipose tissue imaging using the TSPO tracer [18F] fluoromethyl-PBR28-d2: A comparison with [18F] FDG
Deletion of interleukin 1 receptor-associated kinase 1 (Irak1) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle
Thyme oxymel by improving of inflammation, oxidative stress, dyslipidemia and homeostasis of some trace elements ameliorates obesity induced by high …
Obesity and cardiovascular disease: a risk factor or a risk marker?
Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: therapeutic targets for obesity and type 2 diabetes
Adipocyte dysfunction, inflammation, and insulin resistance in obesity
Association of oxytocin with glucose intolerance and inflammation biomarkers in metabolic syndrome patients with and without prediabetes
Vascular risk in obesity: Facts, misconceptions and the unknown
Investigating the Role of LRG1 in Obesity and Adipose Tissue Remodelling
Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
Adipose natural killer cells regulate adipose tissue macrophages to promote insulin resistance in obesity
Mast cell stabilizers obviate high fat diet-induced renal dysfunction in rats
10 Mechanisms Mediating Obesity-Induced Inflammation and Insulin Resistance
Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes
High fat diet and associated changes in the expression of micro‐RNAs in tissue: Lessons learned from animal studies
Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome
Central serotonin transporter availability in highly obese individuals compared with non-obese controls: A [11C] DASB positron emission tomography study
Adiposity as a full mediator of the influence of cardiorespiratory fitness and inflammation in schoolchildren: The FUPRECOL Study
Weight management and physical activity throughout the cancer care continuum
Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness
Obesity and the acute respiratory distress syndrome
Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients
Hypoglycemic activity of 6-bromoembelin and vilangin in high-fat diet fed-streptozotocin-induced type 2 diabetic rats and molecular docking studies
Inflammatory signaling and brown fat activity
Targeting innate immune mediators in type 1 and type 2 diabetes
Brassinin, a phytoalexin in cruciferous vegetables, suppresses obesity‐induced inflammatory responses through the Nrf2‐HO‐1 signaling pathway in an adipocyte …
Treatment of insulin resistance in obesity-associated type 2 diabetes mellitus through adiponectin gene therapy
Training motor responses to food: A novel treatment for obesity targeting implicit processes
Obesity 13 of Diabetes
Levels of metabolic markers in drug-naive prediabetic and type 2 diabetic patients
Obesity as a Disease
Diabetes Mellitus and Glucose Metabolism
Anti-inflammatory actions of (−)-epicatechin in the adipose tissue of obese mice
A phytoestrogen secoisolariciresinol diglucoside induces browning of white adipose tissue and activates non-shivering thermogenesis through AMPK pathway
Effects of mixed carotenoids on adipokines and abdominal adiposity in children: a pilot study
Cellular aging contributes to failure of cold-induced beige adipocyte formation in old mice and humans
2-OHOA supplementation reduced adiposity and improved cardiometabolic risk to a greater extent than n-3 PUFA in obese mice
Obesity causes irreversible mitochondria failure in visceral adipose tissue despite successful anti-obesogenic lifestyle-based interventions
Effect of 8 weeks sprint interval training on serum levels of Adiponectin and insulin in overweight children
Role of mitochondria in the skeletal muscle metabolism in obesity and type 2 diabetes
Insulin-sparing and fungible effects of E4orf1 combined with an adipocyte-targeting sequence in mouse models of type 1 and type 2 diabetes
Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases
IKKβ is essential for adipocyte survival and adaptive adipose remodeling in obesity
Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice
MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced …
Neuroinflammation and white matter alterations in obesity assessed by diffusion basis spectrum imaging
Exercise-induced adaptations to white and brown adipose tissue
The colors of adipose tissue
Lysimachia Capillipes inhibit adipogenesis via angiogenesis inhibition
Neural vulnerability factors that increase risk for future weight gain.
Obesity, estrogens and adipose tissue dysfunction–implications for pulmonary arterial hypertension
Intermittent fasting and ‘metabolic switch’: Effects on metabolic syndrome, prediabetes and type 2 diabetes
Mean Platelet Volume (MPV) as an inflammatory marker in type 2 diabetes mellitus and obesity
Regulatory roles of invariant natural killer T cells in adipose tissue inflammation: defenders against obesity-induced metabolic complications
Glucose-6-phosphate dehydrogenase deficiency improves insulin resistance with reduced adipose tissue inflammation in obesity
Hypothalamic insulin-sensitizing effect of exenatide in dietary induced rat model of obesity
Metabolic Abnormalities and Adipose Tissue Leukocyte Dynamics in a Murine Model of Obesity, Weight Loss, and Weight Regain
Luteolin reduces adipose tissue macrophage inflammation and insulin resistance in postmenopausal obese mice
Adipose tissue inflammation in insulin resistance: review of mechanisms mediating anti-inflammatory effects of omega-3 polyunsaturated fatty acids
Peptides and peptidomimetics as potential antiobesity agents: overview of current status
Sex differences in sympathetic innervation and browning of white adipose tissue of mice
Brown adipose tissue: The heat is on the heart
The stability of children’s weight status over time, and the role of television, physical activity, and diet
Elevated Serum Levels of Adropin in Patients with Type 2 Diabetes Mellitus and its Association with Insulin Resistance Insulin Resistance
Adipokines: potential therapeutic targets for vascular dysfunction in type II diabetes mellitus and obesity
Repeatability of brown adipose tissue measurements on FDG PET/CT following a simple cooling procedure for BAT activation
Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats
Mechanisms of Obesity Induced Impairment of Reproduction
Physical Exercise and White Adipose Tissue Plasticity in the Context of Obesity
Effect of short‐term probiotic Enterococcus faecium SF68 dietary supplementation in overweight and obese cats without comorbidities
Effects of microalgal polyunsaturated fatty acid oil on body weight and lipid accumulation in the liver of C57BL/6 mice fed a high fat diet
Corn oil versus lard: Metabolic effects of omega-3 fatty acids in mice fed obesogenic diets with different fatty acid composition
Obesity, NASH, and HCC
Nanomedicine for obesity treatment
Obesity accelerates age defects in mouse and human B cells
Structured Physical Activity and Dietary Education Program for Obese Adolescents: An Evaluation of a Quality Improvement Project at a Rural Primary Care Clinic
Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation
Differential modulation of white adipose tissue endocannabinoid levels by n-3 fatty acids in obese mice and type 2 diabetic patients
Dietary supplementation with purified citrus limonin glucoside does not alter ex vivo functions of circulating T lymphocytes or monocytes in overweight/obese human …
Current mechanisms in obesity and tumor progression
The role of ceramides in insulin resistance
Endothelial cells: new players in obesity and related metabolic disorders
Fructose-enriched diet induces inflammation and reduces antioxidative defense in visceral adipose tissue of young female rats
Exendin-4 modifies adipogenesis of human adipose-derived stromal cells isolated from omentum through multiple mechanisms
Clinical Manifestations of Insulin Resistance in Youth
Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk
The Aryl Hydrocarbon Receptor and Diet-Induced Obesity: An Investigation of How the Canonical Toxicant Receptor Modulates the Obese State via Activation and …
Catabolic and anabolic faces of insulin resistance and their disorders: a new insight into circadian control of metabolic disorders leading to diabetes
Feeding obese diabetic mice a genistein diet induces thermogenic and metabolic change
Plasma acylcarnitines and amino acid levels as an early complex biomarker of propensity to high-fat diet-induced obesity in mice
Aegeline inspired synthesis of novel β3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance
Functional and molecular adaptations of enteroendocrine L-cells in male obese mice are associated with preservation of pancreatic α-cell function and prevention of …
Roles of daily diet and beta-adrenergic system in the treatment of obesity and diabetes
Type II diabetes mellitus and obesity: Common links, existing therapeutics and future developments
Multiple benefits of targeting inflammation in the treatment of type 2 diabetes
Meta-inflammation and cardiometabolic disease in obesity: Can heat therapy help?
Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
Targeted hyaluronate–hollow gold nanosphere conjugate for anti-obesity photothermal lipolysis
Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF …
Stem cell and obesity: current state and future perspective
Peroxisome proliferator-activated receptor γ in white and brown adipocyte regulation and differentiation
Evaluation of Urolithin, a Pomegranate Metabolite as an Inhibitor of Obesity Driven Endoplasmic Reticulum Stress and Inflammation
The protective effects of Chinese yam polysaccharide against obesity-induced insulin resistance
Urtica dioica Whole Vegetable as a Functional Food Targeting Fat Accumulation and Insulin Resistance-a Preliminary Study in a Mouse Pre-Diabetic Model
Effects of growth hormone on uncoupling protein 1 in white adipose tissues in obese mice
Clinical application potential of small molecules that induce brown adipose tissue thermogenesis by improving fat metabolism
Effect of an 8-week individualized training program on blood biomarkers, adipokines and endothelial function in obese young adolescents with and without metabolic …
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
Insulin resistance in HIV-patients: causes and consequences
Non-glycanated decorin is a drug target on human adipose stromal cells
The effect of saffron on weight and lipid profile: A systematic review, meta‐analysis, and dose–response of randomized clinical trials
Browning of white adipose tissue induced by the ß3 agonist CL-316,243 after local and systemic treatment-PK-PD relationship
Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation
The aryl hydrocarbon receptor in energy balance: the road from dioxin-induced wasting syndrome to combating obesity with ahr ligands
CREG1 heterozygous mice are susceptible to high fat diet-induced obesity and insulin resistance
Flaxseed oil alleviates chronic HFD-induced insulin resistance through remodeling lipid homeostasis in obese adipose tissue
Premature ejaculation in type II diabetes mellitus patients: association with glycemic control
Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity
Beneficial Health Effect of Aquarobics (Role of Adiponectin on Women with Obesity)
Essential roles for the non-canonical IκB kinases in linking inflammation to cancer, obesity, and diabetes
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in …
Dietary Supplementation with Dunaliella Tertiolecta Prevents Whitening of Brown Fat and Controls Diet-Induced Obesity at Thermoneutrality in Mice
Muscle insulin resistance and the inflamed microvasculature: fire from within
Obesity and inflammation: Role of adipokines
Adipose tissue remodeling: its role in energy metabolism and metabolic disorders
MKK6 controls T3-mediated browning of white adipose tissue
A Retrospective Comparative Analysis on the Effectiveness of Pharmacologic Weight Loss
Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice
Latent inflammation and insulin resistance in adipose tissue
Influences of nutritional food label understanding in African-American Women with obesity
Classifying the linkage between adipose tissue inflammation and tumor growth through cancer-associated adipocytes
Effects of recombinant irisin on body mass index, serum insulin, luteinizing hormone and testosterone levels in obese female BALB/c mice
Fibroblast Growth Factor 21 Expression in Mice with Altered Growth Hormone Action: Links to Obesity, Type 2 Diabetes Mellitus, and Increased Longevity
Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women
(-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells
Metabolic and molecular mechanisms of macrophage polarisation and adipose tissue insulin resistance
Interplay between H6PDH and 11β-HSD1 implicated in the pathogenesis of type 2 diabetes mellitus
Curcumin inhibits lipolysis via suppression of ER stress in adipose tissue and prevents hepatic insulin resistance [S]
Humans and mice display opposing patterns of “browning” gene expression in visceral and subcutaneous white adipose tissue depots
Influences of Nutritional Food Label Understanding on African American Women with Obesity
PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced …
Using neuroimaging to investigate the impact of Mandolean® training in young people with obesity: a pilot randomised controlled trial
Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity
Hypoglycaemic effect and mechanism of an RG-II type polysaccharide purified from Aconitum coreanum in diet-induced obese mice
Weight gain is associated with changes in neural response to palatable food tastes varying in sugar and fat and palatable food images: a repeated-measures fMRI …
Managing the Obese Living Kidney Donor
Drugs involved in dyslipidemia and obesity treatment: focus on adipose tissue
Exercise regulation of adipose tissue
Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blind …
Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice
Obesity and Exercice: Effects of different Chronic Exercise Models on visceralapipose tissue from obese animals.
Prohibitin in adipose and immune functions
Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease
Does physical activity-based intervention improve systemic proinflammatory cytokine levels in overweight or obese children and adolescents? Insights from a meta …
Nutritional properties of protein sources on diet-induced obesity, hepatic lipid accumulation, and fatty acid composition in mice
Innate obesity, revealed by selection markers, confers significant imprint of hypothalamic genes controlling energy expenditure
Type 2 diabetes and its impact on the immune system
Molecular mechanisms of insulin resistance: An update
Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue
Chenodeoxycholic acid attenuates high‑fat diet‑induced obesity and hyperglycemia via the G protein‑coupled bile acid receptor 1 and proliferator‑activated …
Heat therapy improves glucose tolerance and adipose tissue insulin signaling in polycystic ovary syndrome
EPA and DHA elicit distinct transcriptional responses to high-fat feeding in skeletal muscle and liver
Pentamethylquercetin induces adipose browning and exerts beneficial effects in 3T3-L1 adipocytes and high-fat diet-fed mice
Adipose tissue: a safe haven for parasites?
GNB3 overexpression causes obesity and metabolic syndrome
PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway
Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment
Searching for evidence of an anti-inflammatory diet in children: a systematic review of randomized controlled trials for pediatric obesity interventions with a focus on …
Weight suppression increases odds for future onset of anorexia nervosa, bulimia nervosa, and purging disorder, but not binge eating disorder
Aspirin mitigated tumor growth in obese mice involving metabolic inhibition
Obese adipose tissue secretion induces inflammation in preadipocytes: Role of Toll-like receptor-4
NAFLD and diabetes mellitus
Efficacy of weight loss intervention can be predicted based on early alterations of fMRI food cue reactivity in the striatum
Mitochondrial Damage Accumulation in Oocytes-A Potential Link Between Maternal Obesity and Increased Cardiometabolic Disease Risk in Offspring
Salsalate activates skeletal muscle thermogenesis and protects mice from high-fat diet induced metabolic dysfunction
Control of brown and beige fat development
A possible Role of Salicylates in Diabetes Type II
Metabolic health, insulin, and breast cancer: why oncologists should care about insulin
Nonalcoholic fatty liver disease induced by high-fat diet in C57bl/6 models
Different and unequal: a qualitative evaluation of salient factors influencing energy intake in adults with overweight and obesity
Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?
Layperson-led vs professional-led behavioral interventions for weight loss in pediatric obesity: a systematic review and meta-analysis
Renal insulin sensitizing effect of exenatide in a high-fat diet obesity rat model
Inflammation in human adipose tissues–Shades of gray, rather than white and brown
Differential expression network analysis for diabetes mellitus type 2 based on expressed level of islet cells
Hypocaloric versus Ad Libitum Diet on Cardiometabolic Markers and Microbiota of Overweight Individuals Performing Intense Exercise
Viral and nonviral transfer of genetic materials to adipose tissues: Toward a gold standard approach
Adipose stromal cell expansion and exhaustion: mechanisms and consequences
Hypertension in diabetes and the risk of cardiovascular disease
The mechanism by which safflower yellow decreases body fat mass and improves insulin sensitivity in HFD-induced obese mice
Postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice
The effects of metformin on high-fat diet-induced neuroinflammation and cognitive impairment
Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells
Unsaturated fatty acids from flaxseed oil and exercise modulate GPR120 but not GPR40 in the liver of obese mice: a new anti-inflammatory approach
Preliminary report of inflammatory markers, oxidative stress, and insulin resistance in adolescents of different ethnicities
Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism
TonEBP in macrophages and adipocytes contributes to obesity and type 2 diabetes
Ageing, colonic health, obesity and the gut microbiota
TNF-α as an adipokine
Parental Self-Efficacy, Feeding Practices and Styles, and Obesity in Mexican American Children
Environmental obesogens and their impact on susceptibility to obesity: new mechanisms
Chronic ephedrine administration decreases brown adipose tissue activity in a randomised controlled human trial: implications for obesity
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Dietary intake, nutritional status and energy metabolism in adolescents with severe obesity-Effects of gastric bypass surgery
Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7
Impact of n-3 Polyunsaturated Fatty Acids on Adipose Tissue Inflammation and Metabolic Control in Severely Obese Patients
Exercise-induced adaptations to adipose tissue thermogenesis
Lack of TRPV 2 impairs thermogenesis in mouse brown adipose tissue
Trends in research and development of phenolic phytochemicals as potential antidiabetic therapeutics
Liraglutide and insulin have contrary effects on adipogenesis of human adipose-derived stem cells via wnt pathway
Linseed oil improves hepatic insulin resistance in obese mice through modulating mitochondrial quality control
The role of HMGB1 in the pathogenesis of type 2 diabetes
Antidiabetic, lipid normalizing, and nephroprotective actions of the strawberry: A potent supplementary fruit
LOSS OF SKELETAL MUSCLE PKCθ PROTECTS AGAINST THE PATHOGENESIS OF INSULIN RESISTANCE
Glucagon-like peptide-2 treatment improves glucose dysmetabolism in mice fed a high-fat diet
Weight loss management in client-owned horses
Reduced number of adipose lineage and endothelial cells in epididymal fat in response to omega-3 PUFA in mice fed high-fat diet
In obese mice, exercise training increases 11β-HSD1 expression, contributing to glucocorticoid activation and suppression of pulmonary inflammation
Harmine induces adipocyte thermogenesis through RAC1-MEK-ERK-CHD4 Axis
Association of Atp2a1 Rs3888190 Single Nucleotide Polymorphism with Obesity and Allergic Conditions among Utar Kampar Campus Students
Schistosoma Infection and Schistosoma-Derived Products Modulate the Immune Responses Associated with Protection against Type 2 Diabetes
Micronutrient supplementation to improve the impact of paternal obesity on subsequent generations
Saponins from Boussingaultia gracilis prevent obesity and related metabolic impairments in diet-induced obese mice
Interplay between dietary sugars and fats and insulin resistance
Inhibition of inflammatory signaling pathways in 3T3‐L1 adipocytes by apolipoprotein A‐I
The Role of Christine A Saponins Molecules in the Control of Mild Chronic Inflammation in Obesity Related with Type-II Diabetes Mellitus
Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
Type 2 diabetes mellitus: Prevalence and risk factors
Potent antihyperglycemic and hypoglycemic effect of Tamarix articulata Vahl. in normal and streptozotocin-induced diabetic rats
Low-intensity exercise in the prevention of cardiac insulin resistance-related inflammation and disturbances in NOS and MMP-9 regulation in fructose-fed …
Alterations in niban gene expression as a response to stress conditions in 3T3-L1 adipocytes
CD8+ T cell/adipocyte inflammatory cross talk and ensuing M1 macrophage polarization are reduced by fish-oil-derived n-3 polyunsaturated fatty acids, in part by a …
β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes
IKK/NF-κB-regulated Inflammatory Pathway in Human Adipocytes: Implication in Subsequent Contribution to Insulin Resistance and Atherosclerosis
Systems biology will direct vascular-targeted therapy for obesity
Remodeling of rat stromal-vascular cells to brite/beige adipocytes by prolyl-hydroxyproline
Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver
Protein kinase A induces UCP1 expression in specific adipose depots to increase energy expenditure and improve metabolic health
Omega-3 fatty acids and adipose tissue biology
Toll-like receptor-4 signaling mediates inflammation and tissue injury in diabetic nephropathy
THE LONG PENTRAXIN 3 PLAYS A KEY ROLE IN THE IMMUNOMODULATION OF DIET-INDUCED OBESITY
Protectin DX ameliorates palmitate-or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice
Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes
Investigation of mechanisms of insulin-regulated lipolysis via ABHD15.
Effects of vaspin on insulin resistance in rats and underlying mechanisms
Deficiency of adipocyte IKKβ affects atherosclerotic plaque vulnerability in obese LDLR deficient mice
11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice
Study on development of brown and beige adipocytes in mice: effect of age and diet-induced obesity
Celastrol attenuates mitochondrial dysfunction and inflammation in palmitate-mediated insulin resistance in C3A hepatocytes
Obesity and Type 2 Diabetes Mellitus: Adipocytokines as Markers of Insulin Resistance
Platelet count and 8-year incidence of diabetes: The Korean Genome and Epidemiology Study
Association between serum C-reactive protein and serum gamma-glutamyl transferase with type 2 diabetes in the Kuopio Ischaemic Heart Disease Risk Factor …
Molecular mechanisms of insulin resistance
The Adipose Organ: Cold Acclimation
Exercise, heat shock proteins and insulin resistance
NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia
Micronutrient deficiency, a novel nutritional risk factor for insulin resistance and Syndrom X
Anti-inflammatory agents in the treatment of diabetes and its vascular complications
Effect of dietary pretreatment and obesity on (-)-epigallocatechin-3-gallate (EGCG) mediated hepatotoxicity and the underlying mechanism
Inflammation is not a contributing factor in the development of insulin resistance in diet induced obesity in rats
Consequences of exposure to maternal diabetes on offspring puberty and adiposity
Browning and Beiging of Adipose Tissue: Its Role in the Regulation of Energy Homeostasis and as a Potential Target for Alleviating Metabolic Diseases …
Uncoupling Lipid Metabolism from Inflammation in Adipose Tissue
RESEARCH ON TYPE 2 DIABETES, INSULIN RESISTANCE, AND THE IMMUNE SYSTEM
Artemisinin mimics nitric oxide to reduce adipose weight by targeting mitochondrial complexes
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Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis
The interaction between prohibitin-1 and sex steroid hormones in adipogenesis
Association Between Single Nucleotide Polymorphisms (SNPs) in the Promoter of Adiponectin Gene, Hypoadiponectinemia, and Diabetes
Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
Theoretical review: Effect of caffeine intake on food consumption patterns and body weight gain
A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate
HOMA-estimated insulin resistance as an independent prognostic factor in patients with acute pancreatitis
w Adherence to Weight Loss and Physical Activity
Transcriptional, Epigenetic and Lipidomic Responses to Metabolic Interventions: Implications for Human Obesity
Rosiglitazone elicits an adiponectin-mediated insulin-sensitizing action at the adipose tissue-liver axis in Otsuka Long-Evans Tokushima fatty rats
Repeated ozone exposure exacerbates insulin resistance and activates innate immune response in genetically susceptible mice
Omega-3 fatty acids as feed supplement modulates blood formation and body weight in Rattus norvegicus model
MKK6 controls T3-mediated browning of white adipose tissue
Associations of brain reactivity to food cues with weight loss, protein intake and dietary restraint during the PREVIEW intervention
IRS proteins and diabetic complications
Intestinal microbial metabolites in human metabolism and type 2 diabetes
Leptin Repolarizes Tumor-Associated Macrophages to Boost Immunotherapy Efficacy in Obesity
Protective effects of Ficus carica leaves on glucose and lipids levels, carbohydrate metabolism enzymes and β-cells in type 2 diabetic rats
Targeted molecular magnetic resonance imaging detects brown adipose tissue with ultrasmall superparamagnetic iron oxide
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Diabetes and sepsis: risk, recurrence, and ruination
Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation
3,5 Diiodo-l-Thyronine (T2) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality
Cross-talk between adipose tissue health, myocardial metabolism and vascular function: the adipose-myocardial and adipose-vascular axes
Adipose tissue: Development, physiology, and pathophysiology
Aptamers: novel diagnostic and therapeutic tools for diabetes mellitus and metabolic diseases
Flaxseed oil attenuates hepatic steatosis and insulin resistance in mice by rescuing the adaption to ER stress
Effects of α-lipoic acid on lipid metabolism and mitochondrial biogenesis in adipocytes: study of the molecular mechanisms involved
Bone Morphogenetic Protein 4 regulates white, beige and brown adipose tissue
Weight management in horses: relationships among digestible energy intake, body weight, and body condition
Graphical abstract Chapter 3: PEDF-induced alteration of metabolism leading to insulin resistance
The Effects of Interleukin-10 on Skeletal Muscle Insulin Resistance and Myogenesis
Duration of a” Brown-Like” Phenotype of White Adipose Tissue Induced by the β3 Agonist CL-316,243
The Anti-Obesogenic Effect of Lean Fish Species Is Influenced by the Fatty Acid Composition in Fish Fillets
Oxygen-Dependent Regulation of Fatty Acid Metabolism and Endoplasmic Reticulum Function in Adipocytes
Lowering effects of aspirin eugenol ester on blood lipids in rats with high fat diet
Fármacos usados no tratamento da dislipidemia e da obesidade: foco no tecido adiposo/Drugs involved in dyslipidemia and obesity treatment: focus on …
Exercise training induces depot-specific adaptations to white and brown adipose tissue
Amelioration of high-insulin-induced skeletal muscle cell insulin resistance by resveratrol is linked to activation of AMPK and restoration of GLUT4 translocation
New advances in our understanding of the control and functions of brown adipose tissue thermogenesis
TSH promotes adiposity by inhibiting the browning of white fat
Association of daily home-based hot water bathing and glycemic control in ambulatory japanese patients with type 2 diabetes mellitus during the COVID-19 pandemic …
Serum CXCL2 Level Can Predict High-Fat Diet-Induced Impairment of Bone Marrow Mesenchymal Stem Cells
Metabolomic response of skeletal muscle to aerobic exercise training in insulin resistant type 1 diabetic rats
Adipose Sensory Nerves: Functional and Neuroanatomical Evidence for Their Emerging Role in Energy Balance
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Small Ubiquitin-Like Modifier 4 (SUMO4) Gene M55V Polymorphism and Type 2 Diabetes Mellitus: A Meta-analysis Including 6,823 Subjects
The effect of concurrent aerobic and resistance exercises on glucose homeostasis and serum HS-CRP in overweight and obese anxious adolescent girls
Therapeutic methods against insulin resistance
Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice
Acute insulin deprivation results in altered mitochondrial substrate sensitivity conducive to greater fatty acid transport
Low-dose aspirin improves glucose uptake and attenuates inflammation in rats fed high-fat diet
Panx1 and Panx3 Regulate Adipocyte Development and Fat Accumulation in Vivo
Mechanisms of action of ginger in nuclear factor-kappaB signaling pathways in diabetes
Adiposity and Health in Zoo African and Asian Elephants
The potential roles of artemisinin and its derivatives in the treatment of type 2 diabetes mellitus
Transgenerational glucose intolerance of tumor necrosis factor with epigenetic alteration in rat perirenal adipose tissue induced by intrauterine hyperglycemia
PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes
Role of macrophages in depot-dependent browning of white adipose tissue
The Effect of Endurance Training on Adiponectin and Insulin Resistance in Overweight Female University Students.
Fármacos Usados no Tratamento da Dislipidemia e da Obesidade: Foco no Tecido Adiposo
In Vitro Effects of Oil’s Fatty Acids on T-Cell Function of Obese Men
Being big, becoming small: conversations with Māori women about weight loss surgery: a thesis presented in partial fulfilment of the requirements for the degree of …
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Food-predicting stimuli differentially influence eye movements and goal-directed behavior in normal-weight, overweight, and obese individuals
Oxidative stress and diabetes: antioxidative strategies
Type 2 Diabetes Mellitus Acts as a Risk Factor for the Development of Early Stage Alzheimer’s Disease
Association between normal triglyceride and insulin resistance in US adults without other risk factors: a cross-sectional study from the US National Health and …
Abscisic acid supplementation rescues high fat diet-induced alterations in hippocampal inflammation and IRSs expression
Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice
Novel Adipose Tissue Targets to Prevent and Treat Atherosclerosis
Diabetic cardiomyopathy: an immunometabolic perspective
Fish and fish oil for cardiovascular disease in diabetes
Effects of Aspirin on metabolic alterations in Type 2 Diabetic Rats
Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner
Interventions for sustainable weight loss in military families
Preventive effect of salicylate and pyridoxamine on diabetic nephropathy
HB-EGF and ADAM 12S directed cellular reprogramming results in metabolically active brown adipose tissue-like cells
Molecular remodeling of the insulin receptor pathway by thiazolidinediones in type 2 diabetes mellitus: A brief review
CD24 is required for gene expression, but not glucose uptake, during adipogenesis in vitro
A novel small molecule A2A adenosine receptor agonist, indirubin-3′-monoxime, alleviates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes
Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway
Monocyte Factors in Pathogenesis of Vascular Lesions in Diabetes
Transcriptome sequencing analysis of peripheral blood of type 2 diabetes mellitus patients with thirst and fatigue
A dietary anthocyanin cyanidin-3-O-glucoside binds to PPARs to regulate glucose metabolism and insulin sensitivity in mice
TO STUDY THE EFFECT OF LAPAROSCOPIC SLEEVE GASTRECTOMY ON BMI AND METABOLIC PARAMETERS IN MORBIDLY OBESE PATIENTS.
Metabolic pathways at the crossroads of diabetes and inborn errors
Glycosaminoglycan from Apostichopus japonicus Improves Glucose Metabolism in the Liver of Insulin Resistant Mice
Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes
Associations between anthropometric traits, detailed body composition, fat fraction per adipose tissue and cardiometabolic risks: differences between children …
Anti-TNF-α antibody alleviates insulin resistance in rats with sepsis-induced stress hyperglycemia
CIDEA transcriptionally regulates UCP1 for britening and thermogenesis in human fat cells
Co-expression of HB-EGF and ADAM 12S displays a brown adipose phenotype in mouse and human cell lines.
Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking
Effects of sodium salicylate on glucose kinetics and insulin signaling in postpartum dairy cows
Metabolic syndrome, brain insulin resistance, and Alzheimer’s disease: Thioredoxin Interacting Protein (TXNIP) and inflammasome as core amplifiers
Retinoid X receptor ligands with anti-type 2 diabetic activity
Complementary cholesterol-lowering response of a phytosterol/α-lipoic acid combination in obese zucker rats
Immunoglobulin free light chains: An inflammatory biomarker of diabetes
The Origin of Human White, Brown, and Brite/Beige Adipocytes
Passive heating and glycaemic control in non-diabetic and diabetic individuals: A systematic review and meta-analysis
Angiogenic factors in the white adipose tissue in childhood
Association between fat mass, adipose tissue, fat fraction per adipose tissue, and metabolic risks: a cross-sectional study in normal, overweight, and obese adults
The Serum Level of KL-6 Is Associated with the Risk of Insulin Resistance and New-onset Diabetes Mellitus: The Tanno-Sobetsu Study
Proinflammatory cytokine polarization in type 2 diabetes
Phenotypic characterization of a novel Ucp1-LUC-iRFP713 reporter mouse model for visualization and quantification of brown and beige fat recruitment
Effect of metabolic syndrome on fertility of male type 2 diabetic mice
Alpha-lipoic acid preserves skeletal muscle mass in type 2 diabetic OLETF rats
Graphical abstract Chapter 2: Molecular aspects of glucose homeostasis in skeletal muscle–A focus on the molecular mechanisms of insulin resistance
XENOGRAFT OF MICROENCAPSULATED SERTOLI CELLS RESTORES GLUCOSE HOMEOSTASIS IN db/db MICE WITH SPONTANEOUS DIABETES …
The Immune Deficiency Pathway Attenuates Insulin Signaling to Protect Against Infection.
Alpha-lipoic acid alleviates acute inflammation and promotes lipid mobilization during the inflammatory response in white adipose tissue of mice
Normal Triglyceride is Associated with Insulin Resistance in the Absence of Risk Factors
Evidence-based psychotherapeutic interventions and mhealth for weight management in overweight: A biopsychosocial framework
The Development and Feasibility of a Culturally Tailored Malaysian Diabetes Education Intervention Using Motivational Interviewing (MY DEUMI) for People …
Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway
Sub-toxic exposure to lindane activates redox sensitive kinases and impairs insulin signaling in muscle cell culture: the possible mechanism of lindane-induced …
Electrochemolipolysis of human adipose tissue
Inhibition of Free fatty acid-Induced Insulin Resistance by Rosemary Extract: Investigation of the Mechanisms Involved
W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein …
Effect of sub-toxic chlorpyrifos on redox sensitive kinases and insulin signaling in rat L6 myotubes
Mutation in Sortilin Identified in an Amish Population Results in Hypercholesterolemia and Insulin Resistance in Mice and Humans
A Role for TNMD in Adipocyte Differentiation and Adipose Tissue Function: A Dissertation
Insulin Resistance and T1D: The Effect of Exercise on Skeletal Muscle Lipid Metabolism
Immunoglobulin Free Light Chains: A Biomarker of Diabetes
Omega-3 fatty acid supplementation combined with acute aerobic exercise does not alter the improved post-exercise insulin response in normoglycemic, inactive and …
The effect of the aerobic continues versus high-intensity interval training on IRE1 expression and its correlation with insulin resistance index of liver tissue in rats …
Synthetic salicylates and/or pioglitazone ameliorative effect in type 2 induced diabetic rats
Flavonoid-enriched extract from desert plant Warionia saharae improves glucose and cholesterol levels in diabetic rats
Improvement of insulin signalling rescues inflammatory cardiac dysfunction
Evaluation of glucose and lipid lowering activity of Arganimide A in normal and streptozotocin-induced diabetic rats
Antidiabetic effect of spearmint in streptozotocin-induced diabetic rats
Aqueous extract of Argania spinosa L. fruits ameliorates diabetes in streptozotocin-induced diabetic rats
Insulin plant (Costus pictus) extract restores thyroid hormone levels in experimental hypothyroidism
Advances in antidiabetic drugs targeting insulin secretion
The Effects of Resistance and Aerobic Training Volume on Body Composition and Adipokines
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Clinical decision-making when treating diabetic macular edema patients with dexamethasone intravitreal implants
Metformin alleviates neuronal and renal related stress signals in diabetic C57BL/6 mice.
Sustained NFjB inhibition improves insulin sensitivity but is detrimental to muscle health
Reversal of obesity development in Ceacam1−/− male mice by bone marrow transplantation or introduction of the human CEACAM1 gene
White adipocyte-targeted dual gene silencing of FABP4/5 for anti-obesity, anti-inflammation and reversal of insulin resistance: Efficacy and comparison of …
Association of a self-paid medically supervised weight management program with reversal of obesity-associated impaired fasting glucose
Reciprocal control of obesity and anxiety–depressive disorder via a GABA and serotonin neural circuit
Loss of function of renal Glut2 reverses hyperglycaemia and normalises body weight in mouse models of diabetes and obesity
Trends in US adolescent physical activity and obesity: A 20‐year age‐period‐cohort analysis
Reversal of hypertriglyceridemia in diabetic BTBR ob/ob mice does not prevent nephropathy
FACI Is a Novel CREB-H–Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity
Swertiamarin ameliorates diet-induced obesity by promoting adipose tissue browning and oxidative metabolism in preexisting obese mice: Swertiamarin …
Obesity and chronic diarrhea: a new syndrome?
Peripheral blood mononuclear cells oxidative stress and plasma inflammatory biomarkers in adults with normal weight, overweight and obesity
Whole-food plant-based lifestyle program and decreased obesity
A Novel Symbiotic Formulation Reduces Obesity and Concomitant Metabolic Syndrome in Rats by Raising the Relative Abundance of Blautia
Dieting reverses histone methylation and hypothalamic AgRP regulation in obese rats
Effectiveness of a population‐scaled, school‐based physical activity intervention for the prevention of childhood obesity
Allograft inflammatory factor-1-like is a situational regulator of leptin levels, hyperphagia, and obesity
Essential Oil of Carvone Chemotype Lippia alba (Verbenaceae) Regulates Lipid Mobilization and Adipogenesis in Adipocytes
Reversing the genomic, epigenetic, and triple-negative breast cancer–enhancing effects of obesity
The impact of weight cycling on health outcomes in animal models: A systematic review and meta‐analysis
Metformin booster adipocyte-targeted gene therapy for the treatment of obesity and related metabolic syndromes
Obesity as a major health hazard
233-LB: Ranolazine Fails to Improve Glycemia in Obese Liver-Specific Pyruvate Dehydrogenase–Deficient Mice
Mechanism of action of acupuncture in obesity: a perspective from the hypothalamus
AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity
Precision nutrition, diet and gut-microbiota in obesity
Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus
Nanotechnology-Based Strategies for Treatment of Obesity, Cancer and Anti-microbial Resistance: Highlights of the Department of Science and Innovation/Mintek …
Fetal programming of obesity and type 2 diabetes
The insulin-sensitizer pioglitazone remodels adipose tissue phospholipids in humans
Association between visceral obesity, metformin use, and recurrence risk in early-stage colorectal cancer
Biomaterial-based therapeutic strategies for obesity and its comorbidities
Obesity and metabolic syndrome in atrial fibrillation: cardiac and noncardiac adipose tissue in atrial fibrillation
Impact of Surgical and Dietary Weight Loss Interventions on the Obesity—Gut Microbiome—Breast Cancer Links
The Effects of Obesity and Bariatric Surgery on Rates of Upper Extremity Compression Neuropathies
Revised Protein Sparing Diet in Obesity and Type 2 Diabetes Mellitus
Stress granules determine the development of obesity-associated pancreatic cancer
The tumor promotional role of adipocytes in the breast cancer microenvironment and macroenvironment
Two-year skeletal effects of sleeve gastrectomy in adolescents with obesity assessed with quantitative CT and MR spectroscopy
Obesity, an independent predictor of pre and postoperative tumor grading disagreement in endometrial cancer
The anti-obesity effect of Allium cepa L. leaves on high fat diet induced obesity in male wistar rats
Turning the clock forward: New pharmacological and non pharmacological targets for the treatment of obesity
Association between socioeconomic positions and overweight/obesity in rural Nepal
Impact of digital monitoring on compliance and outcome of lifestyle-change measures in patients with coexistent atrial fibrillation and obesity
Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis-and senescence-related genes in …
Tumor suppressor Par-4 regulates complement factor C3 and obesity
Obesity Hypertension: Clinical Aspects
Skeletal muscle non-shivering thermogenesis as an attractive strategy to combat obesity
Characterization of Allograft Inflammatory Factor-1-Like (AIF1L) in Diet-Induced Obesity
A novel dual-targeted rosiglitazone-loaded nanoparticle for the prevention of diet-induced obesity via the browning of white adipose tissue
Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer
Obesity and bariatric surgery in kidney transplantation: a clinical review
Weight loss and/or sulindac mitigate obesity-associated transcriptome, microbiome, and protumor effects in a murine model of colon cancer
Are individual or group interventions more effective for long‐term weight loss in adults with obesity? A systematic review
The impact of school-based physical activity programs on obesity prevention
The potential mechanisms of white adipose tissue browning: a novel target for the treatment of obesity.
Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness
Childhood overweight and obesity abatement policies in Europe
Cyclin-dependent kinase 4/6 inhibitors require an arcuate-to-paraventricular hypothalamus melanocortin circuit to treat diet-induced obesity
Brown adipose tissue in adults as a study target in the development of new therapies for the management and treatment of obesity: an integrative review
The gut microbiota as a therapeutic target for obesity: a scoping review
Longitudinal gut microbial signals are associated with weight loss: insights from a digital therapeutics program
Actin related protein 2/3 complex subunit 1 up‐regulation in the hypothalamus prevents high‐fat diet induced obesity
Association between distinct body mass index trajectories according to the group‐based trajectory modeling and the risk of incident diabetes: A systematic review
Epicardial adipose tissue, obesity, and the occurrence of atrial fibrillation: an overview of pathophysiology and treatment methods
MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling
Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity
Role of obesity-induced inflammation in the development of insulin resistance and type 2 diabetes: History of the research and remaining questions
Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
Obese adipose tissue as a driver of breast cancer growth and development: Update and emerging evidence
Characteristic MicroRNAs linked to dysregulated metabolic pathways in qatari adult subjects with obesity and metabolic syndrome
Crosstalk between Melanin Concentrating Hormone and Endocrine Factors: Implications for Obesity
Combining a β3 adrenergic receptor agonist with alpha‐lipoic acid reduces inflammation in male mice with diet‐induced obesity
Regulation of body weight: lessons learned from bariatric surgery
An overview of epigenetics in obesity: The role of lifestyle and therapeutic interventions
Lycopene alleviates ionic disturbances and anaemia by improving iron homeostasis, insulin sensitivity, and ATPases activities in obese female rats
Deciphering biochemical and molecular signatures associated with obesity in context of metabolic health
Gintonin-enriched fraction protects against sarcopenic obesity by promoting energy expenditure and attenuating skeletal muscle atrophy in high-fat diet-fed …
Neuroimaging Investigations of Obesity: a Review of the Treatment of Sex from 2010
Evaluation of a group family-based intervention programme for adolescent obesity: the LITE randomised controlled pilot trial
Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
Zebrafish and flavonoids: adjuvants against obesity
The role of the gut microbiome in pediatric obesity and bariatric surgery
Lycopene abrogates obesity-provoked hyperactivity of neurosignalling enzymes, oxidative stress and hypothalamic inflammation in female Wistar rats
Diet-derived antioxidants and their role in inflammation, obesity and gut microbiota modulation
Enhancing fatty acids oxidation via l-carnitine attenuates obesity-related atrial fibrillation and structural remodeling by activating AMPK signaling and …
Role of obesity related inflammation in pathogenesis of peripheral artery disease in patients of type 2 diabetes mellitus
Potential therapeutic effect of medium chain triglyceride oil in ameliorating diabetic liver injury in a streptozotocin-induced diabetic murine model.
New insights into adipose tissue macrophages in obesity and insulin resistance
Injectable cell-targeting fiber rods to promote lipolysis and inflammatory regulation for obesity treatment
Obesity and altered angiogenic-related gene expression in endometrial cancer
Photoacoustic molecular imaging-escorted adipose photodynamic–browning synergy for fighting obesity with virus-like complexes
Macrophage membrane-camouflaged lipoprotein nanoparticles for effective obesity treatment based on a sustainable self-reinforcement strategy
Involvement of TRP channels in adipocyte thermogenesis: An update
Improved outcomes in rheumatoid arthritis with obesity after a weight loss intervention: randomized trial
Does obesity put your brain at risk?
Transdermal photothermal-pharmacotherapy to remodel adipose tissue for obesity and metabolic disorders
Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice
The impacts of exercise on pediatric obesity
Neural vulnerability factors that predict future weight gain
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CREG1 administration stimulates BAT thermogenesis and improves diet-induced obesity in mice
4-Hydroxyisoleucine alleviates macrophage-related chronic inflammation and metabolic syndrome in mice fed a high-fat diet
Outcome of mini gastric bypass after failed vertical band gastroplasty in treatment of morbid obese patients
Circulating acyl and des-acyl ghrelin levels in obese adults: a systematic review and meta-analysis
Transcriptome sequencing of 3, 3′, 4, 4′, 5-Pentachlorobiphenyl (PCB126)-treated human preadipocytes demonstrates progressive changes in pathways …
Metformin Mitigated Obesity-Driven Cancer Aggressiveness in Tumor-Bearing Mice
Hepatokine Fetuin B expression is regulated by leptin-STAT3 signalling and associated with leptin in obesity
Adipose endothelial cells mastering adipose tissues metabolic fate
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
Effects of Obesogenic Environment on Body Weight Regulation: A Review
The physiologic and physiopathologic roles of perivascular adipose tissue and its interactions with blood vessels and the renin-angiotensin system
Liraglutide suppresses obesity and promotes browning of white fat via miR-27b in vivo and in vitro
Cell death and inflammation during obesity:“Know my methods, WAT (son)”
Adipokines, myokines, and hepatokines: crosstalk and metabolic repercussions
Positive effect of combined exercise on adipokines levels and pubertal signs in overweight and obese girls with central precocious puberty
Obesity as a premature aging phenotype—Implications for sarcopenic obesity
Astragalus mongholicus powder, a traditional Chinese medicine formula ameliorate type 2 diabetes by regulating adipoinsular axis in diabetic mice
N-Trimethylated chitosan coating white adipose tissue vascular-targeting oral nano-system for the enhanced anti-obesity effects of celastrol
Optogenetic activation of UCP1-dependent thermogenesis in brown adipocytes
Piecing together human adult comparative pharmacokinetic trials and rodent studies: What happens to drug clearance in obesity?
Caloric restriction overcomes pre-diabetes and hypertension induced by a high fat diet and renal artery stenosis
Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies
Obesity Is Associated with Immunometabolic Changes in Adipose Tissue That May Drive Treatment Resistance in Breast Cancer: Immune-Metabolic Reprogramming …
Insulin and insulin-like growth factor-1 associated cancers
Macrophages, chronic inflammation, and insulin resistance
Brown/Beige Adipose Tissue: Novel Players in the Fight Against Obesity
3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells
The effect of healthy lifestyle strategies on the management of insulin resistance in children and adolescents with obesity: a narrative review
Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice
Deletion of the feeding-induced hepatokine TSK ameliorates the melanocortin obesity syndrome
Understanding Pericardial Adipose Tissue Mitochondrial Bioenergetics in the Context of Obesity
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis
Induction of lipid catabolism and mitochondrial biogenesis in white adipose tissue as therapeutic target for obesity and associated metabolic disorders
Functionalized nanoformulation based on enriched-triterpenes fraction target adipose tissue, as a potential treatment to obesity and type-2 diabetes: preliminary data
Gut Microbiota Modulation and Its Relationship with Obesity Using Prebiotic Fibers and Probiotics: A
Adipocyte phenotype flexibility and lipid dysregulation
Revisiting the contribution of mitochondrial biology to the pathophysiology of skeletal muscle insulin resistance
Revisiting the Principles of Preservation in an Era of Pandemic Obesity
Progress toward molecular therapy for diabetes mellitus: a focus on targeting inflammatory factors
Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity
Prohibitin inactivation in adipocytes results in reduced lipid metabolism and adaptive thermogenesis impairment
Is overweight still a problem of rich in sub-Saharan Africa? Insights based on female-oriented demographic and health surveys
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Genetic advancements in obesity management and CRISPR–Cas9-based gene editing system
Brain regulation of hunger and motivation: The case for integrating homeostatic and hedonic concepts and its implications for obesity and addiction
Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1β secretion from adipose tissue: The implications for obesity-impaired …
Role of insulin resistance in MAFLD
Antidiabetic and Antioxidant Activity of Zanthoxylum armatum DC. On Type 2 Diabetic Rats.(2022)
New Insights into Adipose Tissue Macrophages in Obesity and Insulin Resistance. Cells 2022, 11, 1424
Regenerative Medicine for Polycystic Ovary Syndrome: Stem Cell-Based Therapies and Brown Adipose Tissue Activation
Obesity and Hepatocellular Carcinoma: Epidemiology and Mechanisms
Impact of inflammasome inhibition on the development of insulin
Jean Himms-Hagen, D. Phil.(1933–2021): Pioneering research in brown adipose tissue thermogenesis
Excessive weight gain and poor growth
Durability of changes in biomarkers of cardiometabolic disease: 1-year family-based intervention in children with obesity
Inhibition of LIFR Blocks Adiposity-Driven Endometrioid Endometrial Cancer Growth
REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation
Inflammatory Mediators and Type 2 Diabetes Risk Factors before and in Response to Lifestyle Intervention among Latino Adolescents with Obesity
Cissus Quadrangularis enhances UCP1 mRNA, indicative of white adipocyte browning and decreases central obesity in humans in a randomized trial
Uncoupling hepatic insulin resistance–hepatic inflammation to improve insulin sensitivity and to prevent impaired metabolism-associated fatty liver disease in …
Effect of 8-Week Short-Term Sprint Interval Training on Serum Levels of Adipokines, Inflammatory Markers and Lipid Profile in Overweight Boys
Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning
What Happens to Adipokines and Cytokine in Overweight and Obese Girls with Central Precocious Puberty When They Exercise and Stop Exercising? A randomized …
Evaluation of serum irisin, retinol-binding protein-4 in human obesity
Browning epicardial adipose tissue: friend or foe?
The adipose organ is a unitary structure in mice and humans
Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects
Thermoregulatory responses, heart rate, and the susceptibility to anxiety in obese animals subjected to stress
Endothelial TrkA coordinates vascularization and innervation in thermogenic adipose tissue and can be targeted to control metabolism
Sodium salicylate induces browning of white adipocytes via M2 macrophage polarization by HO-1 upregulation
Obesity Induced Insulin Resistance, Type 2 Diabetes and Emerging Therapeutic Approaches
Deoxysphingolipids – atypical skeletal muscle lipids related to insulin resistance in humans that decrease insulin sensitivity in vitro
Effect of 8-weeks of Combined Exercise Training on Plasma Leptin and Adiponectin levels in Obese Boys
The Influence of Aerobic Exercise on Extracellular Vesicles in Obesity
Peptide Adjuvant to Invigorate Cytolytic Activity of NK Cells in an Obese Mouse Cancer Model
Endothelial prohibitin mediates bidirectional long-chain fatty acid transport in white and brown adipose tissues
Healthy for My Baby Research Protocol-a Randomized Controlled Trial Assessing a Preconception Intervention to Improve the Lifestyle of Overweight Women …
Effects of N-3 PUFA-Derived Epoxides Combined with sEH Inhibition on Brown Adipose Tissue and Brown Adipocytes in Obesity
Eicosapentaenoic Acid Ethyl Esters Prevent Obesity Associated Metabolic Impairments in Male and Female Mice
Weight Loss Strategies
Mechanisms of Action of Berry Bioactives on Obesity-induced Inflammation
Research Article Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by 𝛽3-Adrenergic Agonist: A Role for MicroRNAs
Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice
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Deconstructing adipose tissue heterogeneity one cell at a time
Manipulation of growth conditions of cyanobacteria to potentiate the production of high value compounds for obesity treatment
Application in medicine: obesity and satiety control
The Role of Catechins in Regulating Diabetes: An Update Review
Tissue-specific insulin sensitivity and changes in brain reward reactivity in overweight or obese pre-diabetic adults
Linseed oil supplementation improves altered lipid metabolism and insulin resistance in induced obese rats
Use of DREADD technology to identify novel targets for antidiabetic drugs
Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes
Factors associated with choice of behavioural weight loss program by adults with obesity
Impact of inflammasome inhibition on the development of insulin resistance in the context of diet-induced obesity
Principal predictors of major adverse limb events in diabetic peripheral artery disease: A narrative review
Sandalwood seed oil ameliorates hepatic insulin resistance by regulating the JNK/NF-κB inflammatory and PI3K/AKT insulin signaling pathways
Browning and Beiging of Adipose Tissue: Its Role in the Regulation of Energy Homeostasis and as a Potential Target for Alleviating Metabolic Diseases …
Effects of ADIPOQ Gene Polymorphisms on Combined Training-induced Weight Loss of Obese Boys
Children With Asparaginase-associated Pancreatitis Present Elevated Levels of Insulin, Total Cholesterol, and HOMA-IR Before Starting Acute Lymphoblastic …
Insulin resistance and cancer: In search for a causal link
Development of predictive models for successful weight loss in people living with obesity
High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control
White adipose tissue depots respond to chronic beta-3 adrenergic receptor activation in a sexually dimorphic and depot divergent manner
Somatic ablation of IKKβ in liver and leukocytes is not tolerated in obese mice but hepatic IKKβ deletion improves fatty liver and insulin sensitivity
Diabetes and Hypertension Prevention in Vanuatu: A Community Service Project
Links between insulin resistance and periodontal bacteria: Insights on molecular players and therapeutic potential of polyphenols
The β3 adrenergic receptor agonist CL316243 ameliorates the metabolic abnormalities of high-fat diet-fed rats by activating AMPK/PGC-1α signaling in skeletal …
The crucial role and mechanism of insulin resistance in metabolic disease
Anthocyanins as promising molecules affecting energy homeostasis, inflammation, and gut microbiota in type 2 diabetes with special reference to impact of acylation
Divergence of Chemerin Reduction by an ATS9R Nanoparticle Targeting Adipose Tissue In Vitro vs. In Vivo in the Rat
Adiponectin synthesis, secretion and extravasation from circulation to interstitial space
Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes
Repurposing lenvatinib as a potential therapeutic agent against thyroid eye disease by suppressing adipogenesis in orbital adipose tissues
Effects of a high-fat diet and global aryl hydrocarbon receptor deficiency on energy balance and liver retinoid status in male Sprague-Dawley rats
Regulatory modules of human thermogenic adipocytes: functional genomics of large cohort and Meta-analysis derived marker-genes
Endothelial cells induced progenitors into Brown fat to reduce atherosclerosis
Calcium-deficiency during pregnancy affects insulin resistance in offspring
Novel biomarkers of inflammation for the management of diabetes: immunoglobulin-free light chains
Diabetes as a potential compounding factor in COVID-19-mediated male subfertility
Altered glucose-dependent secretion of glucagon and ACTH is associated with insulin resistance, assessed by population analysis
A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy …
Insulin resistance in children and adolescents: mechanisms and clinical effects
Glucagon shows higher sensitivity than insulin to grapeseed proanthocyanidin extract (GSPE) treatment in cafeteria-fed rats
Effects of anti-inflammatory therapies on glycemic control in type 2 diabetes mellitus
Effects of a Diabetes Prevention Program among Latino Youth with Prediabetes
Emerging roles of myeloid-derived suppressor cells in diabetes
Characterization of peptides targeting metastatic tumor cells as probes for cancer detection and vehicles for therapy delivery
Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line
Role of mitochondria-associated endoplasmic reticulum membranes in insulin sensitivity, energy metabolism, and contraction of skeletal muscle
Decreased glucocorticoid signaling potentiates lipid-induced inflammation and contributes to insulin resistance in the skeletal muscle of fructose-fed male rats …
Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model
Suppression of estrogen receptor beta classical genomic activity enhances systemic and adipose-specific response to chronic beta-3 adrenergic receptor …
Orexin receptor type 2 agonism inhibits thermogenesis in brown adipose tissue by attenuating afferent innervation
Berberine improves TNF-α-induced hepatic insulin resistance by targeting MEKK1/MEK pathway
Studies on Genotype-Phenotype Correlation in Type II Diabetics and Evaluation of Melatonin and DPP-IV inhibitor on Experimental Diabetic Models
Glucagon Shows Higher Sensitivity than Insulin to Grapeseed Proanthocyanidin Extract (GSPE) Treatment in Cafeteria-Fed Rats. Nutrients 2021, 13, 1084
Anti-and non-tumor necrosis factor-α-targeted therapies effects on insulin resistance in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
CXCL2 impairs functions of bone marrow mesenchymal stem cells and can serve as a serum marker in high-fat diet-fed rats
A simple liking survey captures behaviors associated with weight loss in a worksite program among women at risk of type 2 diabetes
Insights on the role of anti-inflammatory and immunosuppressive agents in the amelioration of diabetes
Insights into the development of insulin resistance: Unraveling the interaction of physical inactivity, lipid metabolism and mitochondrial biology
Plant Protein Consumption and Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis
Expatiating the molecular approaches of HMGB1 in diabetes mellitus: Highlighting signalling pathways via RAGE and TLRs
Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Akt‑glucose transporter 4 signaling pathway and inhibiting …
Effects of 8 Weeks of Combined Rehabilitation Training on Plasma Levels of Leptin, Adiponectin, and Resistin
The Impact of Exercise on Serum Levels of Leptin and Adiponectin in Obese Children and Adolescents: A Systematic Review and Meta-Analysis
The Importance of Education in the Management of Diabetes
Genistein enhances NAD+ biosynthesis by binding to Prohibitin 1 and upregulating nicotinamide phosphoribosyltransferase in adipocytes
The Antidiabetic Activities of Neocryptotanshinone: Screened by Molecular Docking and Related to the Modulation of PTP1B
A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects.
The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism. Antioxidants 2021, 10, 591
Critical material designs for mucus-and mucosa-penetrating oral insulin nanoparticle development
Effects of Korean Food-based Dietary Inflammatory Index Potential on the incidence of diabetes and HbA1c level in Korean adults aged 40 years and older
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance
Recent Advances in Molecular Mechanism of Metformin against Gastrointestinal Cancer in Type 2 Diabetics
Novel Muscle-Homing Peptide FGF1 Conjugate Based on AlphaFold for Type 2 Diabetes Mellitus
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