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Phlorizin
Phlorizin
– Phlorizin is a natural compound found in fruit trees that has been used for over 150 years in pharmaceutical and physiological research.
– Its main pharmacological action is to produce renal glycosuria and block intestinal glucose absorption.
– Phlorizin has played a significant role in the history of diabetes mellitus and has been used as a tool to study renal function.
– It inhibits the sodium-glucose symporters (SGLTs) located in the proximal renal tubule and mucosa of the small intestine.
– Phlorizin has potential uses in the treatment of diabetes, obesity, and stress hyperglycemia.
– It improves insulin sensitivity and normalizes blood glucose levels in diabetic animals.
– Phlorizin has antioxidant properties and may have potential cardiovascular benefits.
– It has been studied for its potential use in the treatment of various conditions, including diabetes, cancer, and neurodegenerative diseases.
PHLORIZIN: a review
Correction of hyperglycemia with PHLORIZIN normalizes tissue sensitivity to insulin in diabetic rats.
On the identity between the small intestinal enzymes PHLORIZIN hydrolase and glycosylceramidase
Transcriptional regulation of the lactase-PHLORIZIN hydrolase gene by polymorphisms associated with adult-type hypolactasia
A method for preparing C-glycosides related to PHLORIZIN
Acute anti‐hyperglycaemic effects of an unripe apple preparation containing PHLORIZIN in healthy volunteers: a preliminary study
Evaluation of the anti-inflammatory effects of phloretin and PHLORIZIN in lipopolysaccharide-stimulated mouse macrophages
Reevaluation of renal tubular glucose transport inhibition by PHLORIZIN analogs
PHLORIZIN prevents glomerular hyperfiltration but not hypertrophy in diabetic rats
The action of PHLORIZIN on the excretion of glucose, xylose, sucrose, creatinine and urea by man
Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase PHLORIZIN hydrolase
Effects of PHLORIZIN and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia
Probing the antioxidant potential of phloretin and PHLORIZIN through a computational investigation
Complete primary structure of human and rabbit lactase‐PHLORIZIN hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme.
Simultaneous separation and purification of total polyphenols, chlorogenic acid and PHLORIZIN from thinned young apples
The human lactase‐PHLORIZIN hydrolase gene is located on chromosome 2
Regulation of lactase–PHLORIZIN hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2
PHLORIZIN-like effect of Fraxinus excelsior in normal and diabetic rats
Energy-dependence of PHLORIZIN binding to isolated renal microvillus membranes
Biosynthesis and maturation of lactase-PHLORIZIN hydrolase in the human small intestinal epithelial cells
Insulin Sensitivity-Enhancing Activity of PHLORIZIN Is Associated with Lipopolysaccharide Decrease and Gut Microbiota Changes in Obese and Type 2 Diabetes (db/db …
PHLORIZIN, a competitive inhibitor of glucose transport, facilitates memory storage in mice
Hypothesis for the interaction of PHLORIZIN and phloretin with membrane carriers for sugars
Normalization of blood glucose in diabetic rats with PHLORIZIN treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose …
Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by PHLORIZIN during ischemia-reperfusion injury in mice
Effect of PHLORIZIN on SGLT2 expression in the kidney of diabetic rats.
Purification and characterisation of amphiphilic lactase/PHLORIZIN hydrolase from human small intestine
PHLORIZIN as a probe of the small-intestinal Na+, D-glucose cotransporter. A model
Fourth ventricular PHLORIZIN dissociates feeding from hyperglycemia in rats
Isolation and characterization of a novel glycosyltransferase that converts phloretin to PHLORIZIN, a potent antioxidant in apple
Competitive inhibition of intestinal glucose transport by PHLORIZIN analogs
Structure of the chromosomal gene and cDNAs coding for lactase-PHLORIZIN hydrolase in humans with adult-type hypolactasia or persistence of lactase.
Renal tubular reabsorption of acetoacetate, inorganic sulfate and inorganic phosphate in the dog as affected by glucose and PHLORIZIN
Beneficial effects of PHLORIZIN on diabetic nephropathy in diabetic db/db mice
Use of PHLORIZIN binding to demonstrate induction of intestinal glucose transporters
On the mode of action of PHLORIZIN as an antimalarial agent in in vitro cultures of Plasmodium falciparum
Investigation of the protective effects of PHLORIZIN on diabetic cardiomyopathy in db/db mice by quantitative proteomics
Further characterization of intestinal lactase/PHLORIZIN hydrolase
PHLORIZIN enhancement of memory in rats and mice
Lactose intolerance and the genetic regulation of intestinal lactase‐PHLORIZIN hydrolase
PHLORIZIN supplementation attenuates obesity, inflammation, and hyperglycemia in diet-induced obese mice fed a high-fat diet
Comparative oral and intravenous pharmacokinetics of PHLORIZIN in rats having type 2 diabetes and in normal rats based on phase II metabolism
Feeding response of Aphis pomi, Myzus persicae, and Amphorophora agathonica to PHLORIZIN
Intestinal lactase-PHLORIZIN hydrolase (LPH): the two catalytic sites; the role of the pancreas in pro-LPH maturation
Inhibition of glucose transport into brain by PHLORIZIN, phloretin and glucose analogues
Interaction between the homeodomain proteins Cdx2 and HNF1α mediates expression of the lactase-PHLORIZIN hydrolase gene
Effects of hyperglycemia on glucose transporters of the muscle: use of the renal glucose reabsorption inhibitor PHLORIZIN to control glycemia.
Inhibition of photophosphorylation by PHLORIZIN and closely related compounds
PHLORIZIN administration increases hepatic gluconeogenic enzyme mRNA abundance but not feed intake in late-lactation dairy cows
… Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptors in Goto-Kakizaki Rats Is Partially Restored by PHLORIZIN Treatment and Accentuated by …
Apple PHLORIZIN attenuates oxidative stress in Drosophila melanogaster
Complex regulation of the lactase-PHLORIZIN hydrolase promoter by GATA-4
Protective effect of apple PHLORIZIN on hydrogen peroxide‐induced cell damage in HepG2 cells
Phloretin and PHLORIZIN promote lipolysis and inhibit inflammation in mouse 3 T 3‐L 1 cells and in macrophage‐adipocyte co‐cultures
Regional localization of the lactase‐PHLORIZIN hydrolase gene, LCT, to chromosome 2q21
Intestinal uptake of quercetin-3-glucoside in rats involves hydrolysis by lactase PHLORIZIN hydrolase
… sites in intestinal lactase-PHLORIZIN hydrolase. Comparison with sucrase-isomaltase and with other glycosidases, the membrane anchor of lactase-PHLORIZIN …
Correction of chronic hyperglycemia with vanadate, but not with PHLORIZIN, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic …
PHLORIZIN recognition in a C-terminal fragment of SGLT1 studied by tryptophan scanning and affinity labeling
Dietary PHLORIZIN enhances osteoblastogenic bone formation through enhancing β-catenin activity via GSK-3β inhibition in a model of senile osteoporosis
PHLORIZIN pretreatment reduces acute renal toxicity in a mouse model for diabetic nephropathy
Molecular and cellular aspects and regulation of intestinal lactase-PHLORIZIN hydrolase
Dietary Supplementation of Apple PHLORIZIN Attenuates the Redox State Related to Gut Microbiota Homeostasis in C57BL/6J Mice Fed with a High-Fat Diet
Coordinate expression of lactase-PHLORIZIN hydrolase mRNA and enzyme levels in rat intestine during development.
Na+‐Dependent and PHLORIZIN‐Inhibitable Transport of Glucose and Cycasin in Brain Endothelial Cells
… β‐glucosidase gene bglA of Clostridium thermocellum Sequence analysis reveals a superfamily of cellulases and β‐glycosidases including human lactase/PHLORIZIN …
Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-PHLORIZIN hydrolase gene
Renal excretion of PHLORIZIN and PHLORIZIN glucuronide
Enzymatic properties of rat lactase-PHLORIZIN hydrolase
Comparative effects of PHLORIZIN and phloretin on glucose transport in the cat kidney
Probing the conformation of the sugar transport inhibitor PHLORIZIN by 2D-NMR, molecular dynamics studies, and pharmacophore analysis
Effects of PHLORIZIN on vascular complications in diabetes db/db mice
Expression of a full-length cDNA coding for human intestinal lactase-PHLORIZIN hydrolase reveals an uncleaved, enzymatically active, and transport-competent protein
PHLORIZIN induced autophagocytosis during hepatocytic glycogenolysis
PHLORIZIN-and 6-ketocholestanol-mediated antagonistic modulation of alamethicin activity in phospholipid planar membranes
d-Glucose-Recognition and PHLORIZIN-Binding Sites in Human Sodium/d-Glucose Cotransporter 1 (hSGLT1): A Tryptophan Scanning Study
PHLORIZIN treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism
Studies on the mechanism of intestinal absorption of sugars VII. Phenylglycoside transport and its possible relationship to PHLORIZIN inhibition of the active transport of …
Effects of salbutamol and PHLORIZIN on acute pulmonary inflammation and disease severity in experimental sepsis
Purified PHLORIZIN from DocynIa Indica (Wall.) Decne by HSCCC, compared with whole extract, PHLORIZIN and non-PHLORIZIN fragment ameliorate obesity, insulin …
Enzymatic synthesis of PHLORIZIN fructosides
P38 and JNK signal pathways are involved in the regulation of PHLORIZIN against UVB‐induced skin damage
PHLORIZIN administration does not attenuate hypophagia induced by intraruminal propionate infusion in lactating dairy cattle
PHLORIZIN receptors in isolated kidney brush border membranes
Impact of O-glycosylation on the function of human intestinal lactase-PHLORIZIN hydrolase. Characterization of glycoforms varying in enzyme activity and …
Genotyping of the lactase-PHLORIZIN hydrolase− 13910 polymorphism by LightCycler PCR and implications for the diagnosis of lactose intolerance
Biosynthesis of intestinal microvillar proteins intracellular processing of lactase-PHLORIZIN hydrolase
Kinetics of Metabolism of Glucose, Propionate and CO2 in Steers as Affected by Injecting PHLORIZIN and Feeding Propionate
Biotransformation of PHLORIZIN by human intestinal flora and inhibition of biotransformation products on tyrosinase activity
Extracellular space estimation in rat kidney slices using C14 saccharides and PHLORIZIN
New insights into lactase and glycosylceramidase activities of rat lactase-PHLORIZIN hydrolase
The effects on renal activity of the oral administration of PHLORIZIN in man
The pro region of human intestinal lactase-PHLORIZIN hydrolase.
Competitive inhibition of PHLORIZIN binding by D-glucose and the influence of sodium: a study on isolated brush border membrane of rat kidney
Hydrolysis by lactase PHLORIZIN hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro
Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-PHLORIZIN hydrolase (LCT) gene in adult-type hypolactasia
Inhibition of glucose absorption by PHLORIZIN affects intestinal functions in rats
HIGH-RESOLUTION RADIOAUTOGRAPHY OF PHLORIZIN-3H IN RINGS OF HAMSTER INTESTINE
AICAR and PHLORIZIN reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat
Benzyl benzoates: New PHLORIZIN analogs as mushroom tyrosinase inhibitors
Effects of PHLORIZIN on metabolism and function of pancreatic β-cell
A novel intestinal trans-factor (NF-LPH1) interacts with the lactase-PHLORIZIN hydrolase promoter and co-varies with the enzymatic activity.
The prosequence of human lactase-PHLORIZIN hydrolase modulates the folding of the mature enzyme
Biosynthesis, glycosylation, and intracellular transport of intestinal lactase-PHLORIZIN hydrolase in rat.
Biogenesis of intestinal lactase-PHLORIZIN hydrolase in adults with lactose intolerance. Evidence for reduced biosynthesis and slowed-down maturation in enterocytes.
Differential mechanism‐based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/PHLORIZIN hydrolase
The comparative effects of some PHLORIZIN analogs on the renal reabsorption of glucose
… comparative study on the metabolism of Epimedium koreanum Nakai-prenylated flavonoids in rats by an intestinal enzyme (lactase PHLORIZIN hydrolase) and intestinal …
Effects of PHLORIZIN on diabetic retinopathy according to isobaric tags for relative and absolute quantification–based proteomics in db/db mice
Transcriptional regulation of pig lactase-PHLORIZIN hydrolase: involvement of HNF-1 and FREACs
Random, presumably hydrolytic, and lysosomal glycogenolysis in the livers of rats treated with PHLORIZIN and of newborn rats
Transmembrane disposition of the PHLORIZIN binding protein of intestinal brush borders
In vitro evaluation of relative inhibitory potency of PHLORIZIN and its congeners
Effect of PHLORIZIN on the osmotic behavior of mitochondria in isotonic sucrose
Some effects of PHLORIZIN on the metabolism of mitochondria
PHLORIZIN inhibition of hypothalamic necrosis induced by gold thioglucose
Two-step mechanism of PHLORIZIN binding to the SGLT1 protein in the kidney
High affinity PHLORIZIN receptor sites and their relation to the glucose transport mechanism in the proximal tubule of dog kidney
Inhibition of [3H] PHLORIZIN binding to isolated kidney brush border membranes by PHLORIZIN-like compounds
PHLORIZIN exerts direct protective effects on palmitic acid (PA)-induced endothelial dysfunction by activating the PI3K/AKT/eNOS signaling pathway and …
Comprehensive Transcriptome Analysis Revealed the Effects of the Light Quality, Light Intensity, and Photoperiod on PHLORIZIN Accumulation in Lithocarpus …
Additional N-glycosylation and its impact on the folding of intestinal lactase-PHLORIZIN hydrolase
Highly selective electrochemical determination of PHLORIZIN using square wave voltammetry at a boron-doped diamond electrode
A study of some effects of PHLORIZIN on the metabolism of kidney tissue in vitro
Characteristics of glucose-PHLORIZIN interactions in isolated proximal tubules
Dietary carbohydrates enhance lactase/PHLORIZIN hydrolase gene expression at a transcription level in rat jejunum
High affinity PHLORIZIN binding to the LLC-PK1 cells exhibits a sodium: PHLORIZIN stoichiometry of 2: 1.
Identification of PHLORIZIN binding domains in sodium-glucose cotransporter family: SGLT1 as a unique model system
Apple PHLORIZIN oxidation product 2 inhibits proliferation and differentiation of 3T3-L1 preadipocytes
Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase PHLORIZIN hydrolase and the sodium-dependent glucose …
Effects of PHLORIZIN on glucose kinetics in the bovine
Effects of PHLORIZIN and acipimox on insulin resistance in STZ-diabetic rats
PHLORIZIN and Trilobatin, Sweet Dihydrochalcone-Glucosides from Leaves of Lithocarpus litseifolius (Hance) Rehd. (Fagaceae)
Evidence for biosynthesis of lactase-PHLORIZIN hydrolase as a single-chain high-molecular weight precursor
Some quantitative studies on PHLORIZIN inhibition of glucose transport in the kidney
Effect of PHLORIZIN on hepatic glucose output
Binding of PHLORIZIN to the Isolated C-Terminal Extramembranous Loop of the Na+/Glucose Cotransporter Assessed by Intrinsic Tryptophan Fluorescence
Short‐term PHLORIZIN treatment attenuates adipose tissue inflammation without alerting obesity in high‐fat diet fed mice
Quantitative proteomics study on the protective mechanism of PHLORIZIN on hepatic damage in diabetic db/db mice
Effects of PHLORIZIN on net chloride movements across the valinomycin-treated erythrocyte membrane
PHLORIZIN exerts potent effects against aging induced by d-galactose in mice and PC12 cells
Insulin but not PHLORIZIN treatment induces a transient increase in GLUT2 gene expression in the kidney of diabetic rats
Lactase-PHLORIZIN hydrolase and sucrase-isomaltase genes are expressed differently along the villus-crypt axis of rat jejunum
Radiation inactivation studies of the renal brush-border membrane PHLORIZIN-binding protein.
Biosynthesis of intestinal microvillar proteins. Dimerization of aminopeptidase N and lactase-PHLORIZIN hydrolase
Expression of lactase-PHLORIZIN hydrolase in sheep is regulated at the RNA level
Pharmacological research on natural substances in Latvia: Focus on lunasin, betulin, polyprenol and PHLORIZIN
A method for measuring apical glucose transporter site density in intact intestinal mucosa by means of PHLORIZIN binding
Interaction of PHLORIZIN and sodium with the renal brush-border membrane D-glucose transporter: stoichiometry and order of binding
The T‐13910C polymorphism in the lactase PHLORIZIN hydrolase gene is associated with differences in serum calcium levels and calcium intake
Rat lactase-PHLORIZIN hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice
Pharmacokinetic and pharmacodynamic modeling of the effect of an sodium-glucose cotransporter inhibitor, PHLORIZIN, on renal glucose transport in rats
PHLORIZIN, an active ingredient of Eleutherococcus senticosus, increases proliferative potential of keratinocytes with inhibition of MiR135b and increased …
Physical interaction between GATA-5 and hepatocyte nuclear factor-1α results in synergistic activation of the human lactase-PHLORIZIN hydrolase promoter
Studies on the inhibition of immune hemolysis by PHLORIZIN
Sodium-glucose cotransporters display sodium-and PHLORIZIN-dependent water permeability
Structure, biosynthesis and regulation of lactase-PHLORIZIN hydrolase
Dual SGLT1/SGLT2 inhibitor PHLORIZIN ameliorates non-alcoholic fatty liver disease and hepatic glucose production in type 2 diabetic mice
Comparison of improving effects for diabetic erectile dysfunction according to the anti-glycemic agents: PHLORIZIN and insulin
Investigation of three doses of oral insulin-like growth factor-I on jejunal lactase PHLORIZIN hydrolase activity and gene expression and enterocyte proliferation …
PHLORIZIN released by apple root debris is related to apple replant disease
Asymmetric inhibition by PHLORIZIN of sulfate movements across the red blood cell membrane
Synthesis of PHLORIZIN derivatives and their inhibitory effect on the renal sodium/D-glucose cotransport system
Similarity in effects of Na+ gradients and membrane potentials on D-glucose transport by, and PHLORIZIN binding to, vesicles derived from brush borders of rabbit …
PHLORIZIN induces lipolysis and alters meal patterns in both early-and late-lactation dairy cows
Effects of PHLORIZIN on membrane cation-dependent adenosine triphosphatase and p-nitrophenyl phosphatase activities
Adrenergic mechanisms in the metabolic adaptation to fasting and feeding: effects of PHLORIZIN on diet-induced changes in sympathoadrenal activity in the rat
Identification of a region critically involved in the interaction of PHLORIZIN with the rabbit sodium-D-glucose cotransporter SGLT1
Some new synthetic flavonoid glycosides related in structure to PHLORIZIN
Glycosylation of lactase-PHLORIZIN hydrolase in rat small intestine during development
Lactase-PHLORIZIN hydrolase and aminopeptidase N are differentially regulated in the small intestine of the pig
PHLORIZIN inhibits hexose transport across the plasmalemma of Riccia fluitans
Transport, function, and sorting of lactase-PHLORIZIN hydrolase in Madin-Darby canine kidney cells.
Modular metabolic engineering for production of phloretic acid, phloretin and PHLORIZIN in Escherichia coli
Lactase-PHLORIZIN hydrolase complex from monkey small intestine: purification, properties and evidence for two catalytic sites
Hierarchy of sorting signals in chimeras of intestinal lactase-PHLORIZIN hydrolase and the influenza virus hemagglutinin
Partial purification of the sugar carrier of intestinal brush border membranes. Enrichment of the PHLORIZIN-binding component by selective extractions
Targeting of sodium–glucose cotransporters with PHLORIZIN inhibits polycystic kidney disease progression in Han: SPRD rats
PHLORIZIN-induced normoglycemia partially restores glucoregulation in diabetic dogs
The HOXC11 homeodomain protein interacts with the lactase-PHLORIZIN hydrolase promoter and stimulates HNF1α-dependent transcription
Follicular phase gonadotropin secretion in cyclic postpartum beef cows with PHLORIZIN-induced hypoglycemia
Partial purification of hog kidney sodium-D-glucose cotransport system by affinity chromatography on a PHLORIZIN polymer
PHLORIZIN administration ameliorates cognitive deficits by reducing oxidative stress, tau hyper‐phosphorylation, and neuroinflammation in a rat model of Alzheimer’s …
Crystal structure of PHLORIZIN and the iodothyronine deiodinase inhibitory activity of phloretin analogues
Recognition of PHLORIZIN by the carriers of sucrose and hexose in broad bean leaves
Oral IGF-I alters the posttranslational processing but not the activity of lactase-PHLORIZIN hydrolase in formula-fed neonatal pigs
β-Glucosidase (PHLORIZIN hydrolase) activity of the lactase fraction isolated from the small intestinal mucosa of infant rats, and the relationship between β-glucosidases …
Dimerization of lactase-PHLORIZIN hydrolase occurs in the endoplasmic reticulum, involves the putative membrane spanning domain and is required for an efficient …
Influence of glucose on the transmembrane action potential of papillary muscle: effects of concentration, PHLORIZIN and insulin, nonmetabolizable sugars, and …
A second enzyme defect in acquired lactase deficiency: lack of small‐intestinal PHLORIZIN‐hydrolase
Asymmetric inhibition by PHLORIZIN of halide movements across the red blood cell membrane
Apple PHLORIZIN supplementation attenuates oxidative stress in hamsters fed a high‐fat diet
High‐affinity PHLORIZIN binding to brush border membranes from small intestine: Identity with (a part of) the glucose transport system, dependence on the Na+‐gradient …
Normalization of glucose entry under the high glucose condition by PHLORIZIN attenuates the high glucose-induced morphological and functional changes of …
Isolation ofn-ethylmaleimide-labelled PHLORIZIN-sensitived-glucose binding protein of brush border membrane from rat kidney cortex
Distribution of sulfhydryl groups in intestinal brush border membranes. Localization of side-chains essential for glucose transport and PHLORIZIN binding.
Enzymatic hydrolysis of pyridoxine-5′-β-d-glucoside is catalyzed by intestinal lactase-PHLORIZIN hydrolase
Sequence of the precursor of intestinal lactase-PHLORIZIN hydrolase from fetal rat
Mitigation effects of PHLORIZIN immersion on acrylamide formation in fried potato strips
Maturation of Human Intestinal Lactase‐PHLORIZIN Hydrolase: Generation of the Brush Border form of the Enzyme Involves at Least Two Proteolytic Cleavage Steps
The Action of PHLORIZIN on Photosynthesis and Light-stimulated Ion Transport in Hydrodictyon africanum
Apple leaves and their major secondary metabolite PHLORIZIN exhibit distinct neuroprotective activities: Evidence from in vivo and in silico studies
Linear relationship of PHLORIZIN‐binding capacity and hexose uptake during differentiation in a clone of LLC‐PK1 cells
PHLORIZIN attenuates visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome
Transcriptional regulation of the lactase-PHLORIZIN hydrolase promoter by PDX-1
APPLICATIONS OF PHLORIZIN AND RECENT ADVANCES OF ITS SEPARATION AND PURIFICATION [J]
Insulin resistance in rats with non-insulin-dependent diabetes induced by neonatal (5 days) streptozotocin: evidence for reversal following PHLORIZIN treatment
Ultrastructure of isolated kidney mitochondria treated with PHLORIZIN and ATP
PHLORIZIN from sweet tea inhibits the progress of esophageal cancer by antagonizing the JAK2/STAT3 signaling pathway
PHLORIZIN binding to isolated enterocytes: membrane potential and sodium dependence
The Pancreatic β-Cell Recognition of Insulin Secretagogues: V. Binding and Stimulatory Action of PHLORIZIN
Effects of PHLORIZIN on glucose, water and sodium handling by the rat kidney.
Protein domains implicated in intracellular transport and sorting of lactase-PHLORIZIN hydrolase
PCR-RFLP genotyping assay for a lactase persistence polymorphism upstream of the lactase-PHLORIZIN hydrolase gene
Structural state of the Na+/d-glucose cotransporter in calf kidney brush-border membranes Target size analysis of Na+-dependent PHLORIZIN binding and Na+ …
Effect of PHLORIZIN on metabolic abnormalities in Spontaneously Diabetic Torii (SDT) rats
Two substrate sites in the renal Na+-d-glucose cotransporter studied by model analysis of PHLORIZIN binding and-d-glucose transport measurements
Studies on the Metabolism of Adipose Tissue. XVI. Inhibition by PHLORIZIN and Phloretin of the Insulin-stimulated Uptake of Glucose*
Inhibition of absorption of d-xylose by PHLORIZIN in the anesthetized rat
An enhancer activates the pig lactase PHLORIZIN hydrolase promoter in intestinal cells
The pro sequence of lactase-PHLORIZIN hydrolase is required for the enzyme to reach the plasma membrane: an intramolecular chaperone?
Lactase PHLORIZIN hydrolase synthesis is decreased in protein-malnourished pigs
Hydrogen ion-coupled transport of D-glucose by PHLORIZIN-sensitive sugar carrier in intestinal brush-border membranes
PHLORIZIN prevents electrically-induced ventricular tachyarrhythmia during ischemia in langendorff-perfused guinea-pig hearts
Novel interaction at the Cdx-2 binding sites of the lactase–PHLORIZIN hydrolase promoter
… under controlled electroosmotic flow and micellar electrokinetic chromatography for on-line concentration and determination of trace PHLORIZIN and quercitrin in urine …
The effect of PHLORIZIN on amino acid transport in rat-kidney-cortex slices
Two intestinal specific nuclear factors binding to the lactase‐PHLORIZIN hydrolase and sucrase‐isomaltase promoters are functionally related oligomeric molecules
Solid-phase synthesis of β-mono-substituted ketones and an application to the synthesis of a library of PHLORIZIN derivatives
Routing and processing of lactase-PHLORIZIN hydrolase in transfected Caco-2 cells
ALKALINE PHOSPHATASE ACTIVITY OF THE PROXIMAL CONVOLUTED TUBULES AND THE MECHANISM OF PHLORIZIN GLYCURESIS
Simultaneous separation and purification of chlorogenic acid, epicatechin, hyperoside and PHLORIZIN from thinned young Qinguan apples by successive use of …
Metabolomics insights of the immunomodulatory activities of PHLORIZIN and phloretin on human THP-1 macrophages
PHLORIZIN inhibition of the insulin expansion of the galactose space in the eviscerate rat
PHLORIZIN treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker …
Proteolytic processing of human lactase-PHLORIZIN hydrolase is a two-step event: identification of the cleavage sites
Effects of PHLORIZIN and p-chloromercuribenzenesulfonic acid on sucrose and proline accumulation in detached tomato leaves submitted to NaCl and osmotic stresses
1 kb of the lactase‐PHLORIZIN hydrolase promoter directs post‐weaning decline and small intestinal‐specific expression in transgenic mice
Treatment of streptozotocin-induced diabetic rats with vanadate and PHLORIZIN prevents the over-expression of the liver insulin receptor gene
Circular dichroism spectra of the inclusion complexes of PHLORIZIN in cyclodextrins
Effects of PHLORIZIN on glucose transport into blood and lymph
Effects of insulin on monosaccharide transport and incorporation of amino acids into protein in diaphragm differentiated with PHLORIZIN
Effect of glucose, PHLORIZIN, and parathyroid extract on renal phosphate transport in chickens
PHLORIZIN ameliorates obesity-associated endotoxemia and insulin resistance in high-fat diet-fed mice by targeting the gut microbiota and intestinal barrier integrity
The effect of PHLORIZIN on the multiplication of measles virus
Studies on the arrangement of a glucose sensitive PHLORIZIN binding site in the microvilli of isolated rat kidney brushborder
PHLORIZIN and renal phosphate secretion in the spiny dogfish Squalus acanthias
Developmental changes in lactase-PHLORIZIN hydrolase precursor isoforms in the rat.
The inhibition by PHLORIZIN of kidney microsomal inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphatase
In vivo sucrase-isomaltase and lactase-PHLORIZIN hydrolase turnover in the fed adult rat
Maturation of human lactase‐PHLORIZIN hydrolase Proteolytic cleavage of precursor occurs after passage through the Golgi complex
Quantitation of PHLORIZIN and phloretin using an ultra high performance liquid chromatography–electrospray ionization tandem mass spectrometric method
Transepithelial transport in cell culture: Stoichiometry of Na/PHLORIZIN binding and Na/D-glucose cotransport. A two-step, two-sodium model of binding and …
Further studies of glycosylation and intracellular transport of lactase–PHLORIZIN hydrolase in rat small intestine
PHLORIZIN: its effect on glucose-induced insulin secretion and protection against the alloxan effect in isolated islets
Hepatocyte nuclear factor-1α is required for expression but dispensable for histone acetylation of the lactase-PHLORIZIN hydrolase gene in vivo
Competitive inhibition of SGLT2 by tofogliflozin or PHLORIZIN induces urinary glucose excretion through extending splay in cynomolgus monkeys
A hydrolase-related transport system is not required to explain the intestinal uptake of glucose liberated from PHLORIZIN
Abnormal B-cell function in rats with non-insulin-dependent diabetes induced by neonatal streptozotocin: effect of in vivo insulin, PHLORIZIN, or vanadate treatments.
Studies on transmural potentials in vitro in relation to intestinal absorption: IV. PHLORIZIN-sugar interactions in rat gut
Interrelations during renal tubular reabsorption in the dog among several anions showing a sensitivity to glucose and PHLORIZIN
Inhibition by PHLORIZIN of insulin-and protease-stimulated glucose utilization in isolated adipose cells
PHLORIZIN-induced glycosuria does not prevent gentamicin nephrotoxicity in rats
Derivatives of Plant Beta-GIucans Are Hydrolyzed by Intestinal Lactase-PHLORIZIN Hydrolase of Mammals
Processing of human pro-lactase-PHLORIZIN hydrolase at reduced temperatures: cleavage is preceded by complex glycosylation
Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor PHLORIZIN
Verification of the lactase site of rat lactase-PHLORIZIN hydrolase by site-directed mutagenesis
Insulin, anaerobiosis, and PHLORIZIN in entry of d-galactose into skeletal muscle
Mechanism of maturational decline of rat intestinal lactase-PHLORIZIN hydrolase
A comparative study of intestinal PHLORIZIN hydrolase in various animal species
Folding of human intestinal lactase-PHLORIZIN hydrolase
Action of PHLORIZIN on Acid Phosphatase Activity and on Glucose Phosphorylation of Kidney Cortex Extracts.
Hypoglycemic and hypolipidemic activities of PHLORIZIN from Lithocarpus polystachyus Rehd in diabetes rats
Genetic regulation of enterocyte function: a quantitative in situ hybridisation study of lactase-PHLORIZIN hydrolase and Na+-glucose cotransporter mRNAs in rabbit small …
Apple PHLORIZIN reduce plasma cholesterol by down-regulating hepatic HMG-CoA reductase and enhancing the excretion of fecal sterols
Processing and transport of human small intestinal lactase-PHLORIZIN hydrolase (LPH): Role of N-linked oligosaccharide modification
Effects of PHLORIZIN and ouabain on the polarity of mouse 4-cell/16-cell stage blastomere heterokaryons
Effects of glucose, 2-deoxyglucose, PHLORIZIN, and insulin on food intake of lean and fatty rats
Action of PHLORIZIN on luminal and antiluminal membranes of proximal cells of kidney
Studies on the Inhibitors of the Sodium-Potassium Activated Adenosinetriphos phatase. I. Effect of PHLORIZIN and Related Natural Products
The effect of PHLORIZIN on the metabolism of cytolysing sea-urchin eggs
Isolation and partial purification of a Na+-dependent PHLORIZIN receptor from dog kidney proximal tubule.
Demonstration of glucose inhibitable PHLORIZIN binding to renal brushborder proteins separated by gel electrophoresis
A two sodium ion/D-glucose symport mechanism: membrane potential effects on PHLORIZIN binding
Small-intestinal Na+/D-glucose cotransport. Inactivation of sugar transport and PHLORIZIN binding by thiol-group and amino-group reagents
N-ethylmaleimide labeling of a PHLORIZIN-sensitive D-glucose binding site of brush border membrane from the rat kidney
Region-specific expression of multiple lactase-PHLORIZIN hydrolase genes in intestine of rabbit
Regulatory regions in the rat lactase-PHLORIZIN hydrolase gene that control cell-specific expression
Specific photoaffinity inactivation of the D-glucose transporter in small intestinal brush border membrane using new PHLORIZIN analogs
The kinetic advantage for transport into hamster intestine of glucose generated from PHLORIZIN by brush border β-glucosidase
Isolation and characterization of the proximal and distal forms of lactase-PHLORIZIN hydrolase from the small intestine of the suckling rat
Studies on the spatial relationship between intestinal disaccharidases and the PHLORIZIN-sensitive transport of glucose
Systemic PHLORIZIN prevents gold thioglucose necrosis in the ventromedial hypothalamus
Genotyping of the Lactase-PHLORIZIN Hydrolase C/T-13910 Polymorphism by Means of a New Rapid Denaturing High-Performance Liquid Chromatography-Based …
Effect of PHLORIZIN on the in Vitro Release of Histamine from Lung Tissue1
Biotransformation of PHLORIZIN by Eurotium cristatum to Increase the Antioxidant and Antibacterial Activity of Docynia indica Leaves
Proteolytic processing of human intestinal lactase-PHLORIZIN hydrolase precursor is not a prerequisite for correct sorting in Madin Darby canine kidney (MDCK) cells
PHLORIZIN treatment attenuates obesity and related disorders through improving BAT thermogenesis
Synthesis of [3H] PHLORIZIN and its binding behavior to renal brush-border membranes
Light activation of pyruvate, Pi dikinase and NADP-malate dehydrogenase in mesophyll protoplasts of maize: effect of DCMU, antimycin A, CCCP, and PHLORIZIN
Effect of PHLORIZIN on exchange and non-exchange transport of sugars in human erythrocytes
The effects of PHLORIZIN stress on the protective enzyme and metabolic regulation substances in the root of M. micromalus
PHLORIZIN or vanadate treatment reverses impaired expression of albumin and hepatocyte nuclear factor 1 in diabetic rats
Hymenolepis diminuta: properties of PHLORIZIN inhibition of glucose transport
The pro-region of human intestinal lactase-PHLORIZIN hydrolase is enzymatically inactive towards lactose.
Immunocytochemical heterogeneity of lactase-PHLORIZIN hydrolase in adult lactase deficiency
The apical sorting of lactase-PHLORIZIN hydrolase implicates sorting sequences found in the mature domain.
Quantitative analysis of lactase‐PHLORIZIN hydrolase expression in the absorptive enterocytes of newborn rat small intestine
On the absence of PHLORIZIN hydrolase in renal brush border membranes
Oligomeric structure of the sodium-dependent PHLORIZIN binding protein from kidney brush-border membranes
Effects of glucagon, glycerol, and insulin on PHLORIZIN-induced ketosis in fasted, non-pregnant ewes.
The effects of PHLORIZIN, phloretin and ouabain on the reabsorption of glucose by the Malpighian tubules of Locusta migratoria migratorioides
Is PHLORIZIN or its aglycon the inhibitor of intestinal glucose transport? A study in normal and lactase deficient man
The affinity of PHLORIZIN-like compounds for a β-glucosidase in intestinal brush borders: comparison with the glucose transport system
Study on Inhibitory Activity of PHLORIZIN against Tyrosinase [J]
Human lactase–PHLORIZIN hydrolase: evidence of dimerization in the endoplasmic reticulum
Interaction of PHLORIZIN, a potent inhibitor of the Na+/D‐glucose cotransporter, with the NADPH‐binding site of mammalian catalases
Different PHLORIZIN binding properties to porcine mucosa of the jejunum and ileum in relation to SGLT1 activity
Immunomodulatory activities of PHLORIZIN metabolites in lipopolysaccharide-stimulated RAW264. 7 cells
The lactase PHLORIZIN hydrolase (LCT) gene maps to pig chromosome 15q13
Suckling rat colon synthesizes and processes active lactase-PHLORIZIN hydrolase immunologically identical to that from jejunum
The Crystal and Molecular Structure of PHLORIZIN Dihydrate
Induction of ependymal, glial, and neuronal transactivation by intraventricular administration of the SGLT1 Na+-D-glucose cotransporter inhibitor PHLORIZIN
Binding of PHLORIZIN to the C-terminal loop 13 of the Na+/glucose cotransporter does not depend on the [560–608] disulfide bond
High-affinity PHLORIZIN binding in Mytilus gill
Competitive kinetics in the inhibition of sugar intestinal transport by PHLORIZIN, in vivo.
Furin, PC1/3, and/or PC6A Process Rabbit, but Not Human, Pro-lactase-PHLORIZIN Hydrolase to the 180-kDa Intermediate (∗)
Effects of PHLORIZIN and heparin on ketonemia in fasted, nonpregnant ewes.
Pharmacological investigations on efficacy of PHLORIZIN a sodium-glucose co-transporter (SGLT) inhibitor in mouse model of intracerebroventricular streptozotocin …
A possible role of a nuclear factor NF-LPH1 in the regional expression of lactase-PHLORIZIN hydrolase along the small intestine
Molecular interaction of PHLORIZIN and cyclodextrins
Paradoxical effect of PHLORIZIN on glucose uptake and intracellular accumulation of amino-acids in rat kidney slices in vitro
Restoration of the Attenuated Neuroprotective Effect of Ischemic Postconditioning in Diabetic Mice by SGLT Inhibitor PHLORIZIN
Human lactase‐PHLORIZIN hydrolase expressed in COS‐1 cells is proteolytically processed by the lysosomal pathway
Heterogeneity of intestinal lactase activity in children: relationship to lactase-PHLORIZIN hydrolase messenger RNA abundance
Study on the dynamic changes of PHLORIZIN and phloretin in leave and branches of apple tree.
PHLORIZIN stimulation of p-aminohippurate uptake in rat kidney cortex slices
Enzymatic Production of 3-OH PHLORIZIN, a Possible Bioactive Polyphenol from Apples, by Bacillus megaterium CYP102A1 via Regioselective Hydroxylation
EFFECTS OF 2-DEOXYGLtJCOSE, PHLORIZIN, INSULIN AND OUABAIN ON GLUCOSE-DEPENDENT ANAPHYLACTIC HISTAMINE RELEASE FROM GUINEA-PIG …
Preparative isolation and purification of PHLORIZIN from apple tree bark by high-speed counter-current chromatography.
Structural determinants for transport of lactase PHLORIZIN-hydrolase in the early secretory pathway as a multi-domain membrane glycoprotein
Antecedent chronic hyperglycaemia blocks PHLORIZIN-induced insulin resistance in the dog
Hexosamine metabolism II. effect of insulin and PHLORIZIN on the absorption and metabolism, in vivo, of d-glucosamine and N-acetyl-d-glucosamine in the rat
PHLORIZIN receptors in isolated kidney brush border membranes Differential enzymatic modification of high-affinity receptors and unspecific binding sites
PHLORIZIN glycosuria in the diagnosis of pregnancy
Effect of PHLORIZIN on galactose influx in rabbit intestine
… competitive inhibition and activation in Michaelian enzyme and transport systems. Application to the competitive inhibition of glucose transport in brain by PHLORIZIN …
In Vivo Absorption of Phenytoin from Rat Small Intestine and its Inhibition by PHLORIZIN
Thyroid and glucocorticoid hormones induce expression of lactase-PHLORIZIN hydrolase gene in CDX-2/HNF-1α co-transfected IEC-6 cells
Fluorescence probe studies on the interaction of PHLORIZIN with rabbit intestinal brush border membranes
The interaction of phenformin and PHLORIZIN with brush border membrane vesicles, phospholipid liposomes, and phospholipid liposomes containing brush border …
Identification and characterization of PHLORIZIN transporter from Arabidopsis thaliana and its application for PHLORIZIN production in Saccharomyces cerevisiae
Deglycosylation of individual flavonoids and flavonoid containing plant extracts by purified human intestinal lactase-PHLORIZIN hydrolase (LPH)
Translocation of organic compounds in sunflower III. Effect of oligomycin, ouabain and PHLORIZIN on translocation of sugars
Effects of epinephrine, hydrocortisone, and thyroxine on PHLORIZIN-induced ketosis in fasted, nonpregnant ewes.
D‐glucose transporter on mussel mantle cell membranes: Effect of sodium and PHLORIZIN
Rabbit intestinal glucose-6-phosphate phosphohydrolase and inorganic pyrophosphate glucose phosphotransferase: inhibition by PHLORIZIN
Lactase and PHLORIZIN hydrolase from rabbit small intestine
A PHLORIZIN Polymer as Affinity Gel for Sugar‐Binding Proteins
Disposition of the car☐ y-terminus tail of rabbit lactase-PHLORIZIN hydrolase elucidated by phosphorylation with protein kinase A in vitro and in tissue culture
Lactase-PHLORIZIN hydrolase complex from monkey small intestine: Stimulation of pillorizin hydrolase activity by organic acids
Purification of a putative Na+ /D‐glucose cotransporter from pig kidney brush border membranes on a PHLORIZIN affinity column
Study on interaction between PHLORIZIN and human serum albumin by spectroscopic methods
In vitro hepatic gluconeogenesis during experimental ketosis produced in steers by 1, 3-butanediol and PHLORIZIN
Effect of PHLORIZIN treatment on postharvest gray mold of apples.
Protein metabolism in PHLORIZIN diabetes
Changes in glucose uptake by and PHLORIZIN binding to brush-border membrane vesicles of small intestine from streptozotocin-induced diabetic rats
… acid sequence and mRNA analysis of cytosolic pyridoxine-beta-D-glucoside hydrolase from porcine intestinal mucosa: proposed derivation from the lactase-PHLORIZIN …
D-galactose uptake by snail intestine: competitive inhibition by PHLORIZIN and sodium dependence.
Effect of PHLORIZIN on the changes of membrane potential, water, Na and K transport induced by cevadine in frog muscle.
… BETWEEN DNA METHYLATION OF THE CHALCONE ISOMERASE GENE IN LITHOCARPUS POLYSTACHYUS REHD.(FAGACEAE) AND PHLORIZIN …
Isoosmotic Transport of Fluid Across the Hamster Small Intestine in the Presence of PHLORIZIN-Induced Inhibition of Sugar Transport
The inhibition of glucose-6-phosphatase by PHLORIZIN and structurally related compounds
Administration of 3, 5, 3’‐triiodothyronine induces a rapid increase in enterocyte lactase‐PHLORIZIN hydrolase activity of young pigs on a low energy intake
Investigating the stimulatory mechanisms of PHLORIZIN, phloretin and chlorogenic acid polyphenols on Akkermansia muciniphila in vitro
PHLORIZIN binding to bilayer vesicles of phospholipids and phospholipid-cholesterol
Some effects of PHLORIZIN and phloretin on renal amino acid reabsorption in the dog
Substrate oxidation by isolated ovine enterocytes is increased by PHLORIZIN-induced glucosuria
PHLORIZIN and sorbitol in Vitis labrusca grape juices
Study on Extraction Technology of PHLORIZIN in Litchi Pericarp [J]
The PHLORIZIN effect on the transport of sugars at the antiluminal face of teased flounder tubules.
PHLORIZIN-receptor interactions in fat cell plasma membranes
Studies on the mechanism of action of PHLORIZIN
[43] Photoafflnity-labeling analogs of PHLORIZIN and phloretin: Synthesis and effects on cell membranes
Effect of PHLORIZIN on hepatic bile production before and during glucose infusion
… ) phenoxy]-d-glucopyranoside and [(4′-benzoyl) phenoxy]-d-glucopyranoside for the identification of sugar-binding and PHLORIZIN-binding sites in the sodium/d …
Molecular cloning of a novel cDNA from Mus muscular BALB/c mice encoding glycosyl hydrolase family 1: a homolog of human lactase-PHLORIZIN hydrolase.
Structure, Function, and Regulation of Intestinal Lactase-PHLORIZIN Hydrolase and Sucrase-Isomaltase in Health and Disease
A comparison of PHLORIZIN and phloretin adsorption by the tapeworm Hymenolepis diminuta.
Analysis of the proteolytic processing of lactase-PHLORIZIN hydrolase
Effect of PHLORIZIN on the action potential and voltage-dependent ionic conductances in frog skeletal muscle.
Persistence of disturbed adipocyte metabolism in sterptozocin-induced diabetic rats despite near-euglycemia with PHLORIZIN
The combined action of insulin and PHLORIZIN on transport and metabolism of sugars and nucleotide turnover in the isolated rat diaphragm
Reduction in the Amplitude of Shortening and Ca2+ Transient by PHLORIZIN and Quercetin-3-O-Glucoside in Ventricular Myocytes From Streptozotocin-Induced …
Chloride-dependence of the actions of PHLORIZIN on frog skeletal muscle membrane.
Amelioration of PHLORIZIN-induced autotoxicity in Malus hupehensis by rhizobium
Effect of PHLORIZIN on glucose transport in the inner ear
The mechanism of coupling between glucose transport and electrical potential in the proximal tubule: A study of potential-dependent PHLORIZIN binding to isolated renal …
Binding of [3H] PHLORIZIN to rat kidney plasma membranes
PHLORIZIN derivatives as photoaffinity labels of the Na+, D-glucose transporter in brush border membranes
The action of inhibitors of sugar transport PHLORIZIN, phloretin and cytochalasin B in model systems
Inhibition of sodium for sodium exchange by PHLORIZIN in frog sartorius muscle.
Defective Intracellular Processing of Lactase‐PHLORIZIN Hydrolase Protein in Rats Prenatally Exposed to Ethanol
… Reactive Ezrin Surface Area Increases in Glomerular Podocytes of STZ Diabetic Rats Precede Their Detachment, Is Prevented by PHLORIZIN But Not by Insulin
PHLORIZIN vs
The role of transporter ectodomains in drug recognition and binding: PHLORIZIN and the sodium–glucose cotransporter
Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-PHLORIZIN hydrolase (LPH) 5′ flanking sequence
Variations in the acid-base equilibrium in hypoglycemic PHLORIZIN diabetes.
Effects of PHLORIZIN and phloretin on passive and dynamic electrical properties in muscle membrane.
LXI.—On PHLORIZIN
The Effects of PHLORIZIN, 2, 4-dinitrophenol, and Oxygen Deprivation on the Intestinal Transport of D-glucose
Human lactase-PHLORIZIN hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases
Immunoelectron Microscopic Localization of Lactase-PHLORIZIN Hydrolase in Rat Small Intestine
Do co-translated product (s) of lactase-PHLORIZIN hydrolase accumulate in the rat intestine?
Characterization of natural and artificial mutants of human intestinal lactase PHLORIZIN hydrolase
Distinguishing between hydrophilic and hydrophobic subunits of human lactase-PHLORIZIN hydrolase by gel filtration
I. INHIBITION OF PHOTOPHOSPHORYLATION BY PHLORIZIN
In-Vitro Antioxidant Activity and Free Radical Scavenging Potential of PHLORIZIN Derived Sodium Glucose Cotransporter 2 Inhibitor
THE INTRAVENOUS PHLORIZIN TEST
Effects of PHLORIZIN on Renal Function
THE EFFECT OF PHLORIZIN UPON GLOMERULAR FILTRATION
Photo-activated inhibition of sulfate equilibrium exchange in human erythrocyte ghosts by A 4-azido-2-nitrobenzoate derivative of PHLORIZIN
Interaction and Antioxidant Activities of PHLORIZIN and Bovine Hemoglobin in Three Different Solvents
Comparition of PHLORIZIN recovery with different solid phase extraction cartridges
Isolation, Identification and Degrading Properties of PHLORIZIN-Degrading Fungi
A STUDY OF SOME EFFECTS OF PHLORIZIN ON THE METABOLISM OF KIDNEY TISSUE IN VITRO
Effects of PHLORIZIN on aorta of diabetes db/db mice
Lack of effect of charge of PHLORIZIN and phloretin on mutarotase action
Purification of PHLORIZIN from Malus domestica Borkh. leaves by solid-phase extraction and semi-preparative high performance liquid chromatography.
Therapeutic effects of PHLORIZIN on the early stage of diabetic retinopathy in diabetic db/db mice
High affinity PHLORIZIN binding to the small intestinal Na exp+, D-glucose carrier
The effects of PHLORIZIN on serum lipid profile and oxidative stress parameters in sheep.
Effect of PHLORIZIN on sugar uptake by broadbean leaf discs.[Vica faba L]
Expression and characterization of Lactase PHLORIZIN Hydrolase region III.
Interaction of PHLORIZIN and phloretin with glucose transport system of the pigeon intestine
Component analysis of Valsa mali var. mali fermentation liquid degrading PHLORIZIN
Component analysis of Valsa mali var. mali fermentation liquid degrading PHLORIZIN.
Bioconversion of PHLORIZIN to phloretin by a selected Penicillium purpurescens strain QL-9204
Enhancement of Gibberellic Acid-stimulated Hypocotyl Elongation of Lettuce (Lactuca sativa L. cv. Grand Rapids) by PHLORIZIN and Light
Lactase-PHLORIZIN hydrolase: primary structure determination via cDNA cloning of the rabbit enzyme and developmental regulation in rabbit and human
Hyperglycæmia following absorption of glucose in dogs subjected to different treatments: normal diet, high sugar diet, starvation, injection of PHLORIZIN.
The Influence on the Yield of PHLORIZIN in Lithocarpus Polysachyus Rehd Fermented by Saussurea Bacteria
PHLORIZIN Significantly Increases Glucosuria in Normoglycemic Rats but not in Zucker Diabetic Fatty (ZDF) or Streptozotocin-Induced (STZ) Diabetic Rats
GLYCOSYLATION OF LACTASE-PHLORIZIN HYDROLASE (L-Ph) IN RAT SMALL INTESTINE DURING DEVELOPMENT
COORDINATE EXPRESSION OF LACTASE-PHLORIZIN HYDROLASE (L-PH) mRNA AND ENZYME LEVELS IN RAT INTESTINE DURING DEVELOPMENT
The biochemical and genetical analysis of lactase PHLORIZIN hydrolase: with specific reference to the lactase persistence/non-persistence polymorphism in …
P003: PHLORIZIN, an active ingredient of eleutherococcus senticosus, increases proliferative activity of keratinocytes with increased expression of type iv collagen and …
INTESTINAL ABSORPTION OF GLUCOSE HYDROLYZED FROM PHLORIZIN BY A BRUSH BORDER GLYCOSIDASE AND AN AFFINITY CHROMATOGRAPHY …
49 SEQUENCE VARIABILITY AMONG THE PROMOTER REGION OF THE HUMAN LACTASE-PHLORIZIN HYDROLASE (LPH) GENE
Routing of normal and mutant brush-border sucrase-isomaltase and lactase-PHLORIZIN hydrolase
PRIMARY SEQUENCE OF CODING RECION OF LACTASE-PHLORIZIN HYDROLASE GENE IN CONGENITAL HUMAN LACTASE DEFICIENCY
Hepatocyte nuclear factor-1alpha is required for gene-expression, but dispensable for histone acetylation of the lactase-PHLORIZIN hydrolase gene
PHLORIZIN Treatment Of Zucker Diabetic Fatty (ZDF) Rats For One Week Decreased Blood Glucose And Triglycerides Without Significant Alterations of Urine Volume …
1. 48 to 6. 28+ 1. 20 pmol/mm min (P & 0.01) when glucose was added to the perfusate. PHLORIZIN 10-5M in the lumen reduced the lumen
48 RAT LACTASE-PHLORIZIN HYDROLASE HAS ONE MAIN ACTIVE SITE WITH B-GLUCOSIDASE AND B-GALACTOSIDASE ACTIVITY
… STUDIES WITH HYPOGLYCEMIC AND KETONEMIC SHEEP. I. EFFECTS OF GLUCAGON, GLYCEROL AND INSULIN ON PHLORIZIN-INDUCED KETOSIS IN …
EFFECTS OF 2-DEOXYGLtJCOSE, PHLORIZIN, INSULIN AND OUABAIN ON GLUCOSE-DEPENDENT ANAPHYLACTIC HISTAMINE RELEASE FROM GUINEA-PIG …
(18) Biodiversity of the Flavonoid PHLORIZIN in a Subset of the USDA Apple Germplasm Core Collection
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