Oncogene Activation

Oncogene activation plays a critical role in human health and aging, but it’s a double-edged sword. Oncogenes are genes that, when activated, promote uncontrolled cell growth and division, a hallmark of cancer. This uncontrolled growth disrupts tissue function and can lead to tumor formation. Mutations or increased expression of oncogenes are found in most cancers, highlighting their importance in cancer development.
However, under normal circumstances, some oncogenes play beneficial roles in cellular processes like development,wound healing, and regeneration. In these cases, tight regulation of oncogene activity is crucial. Aging is associated with a decline in these cellular processes, and some research suggests that low-level oncogene activation might be a compensatory mechanism to counteract this decline. However, this activation needs to be carefully balanced, as excessive or prolonged activation can still tip the scales towards cancer. Understanding the complex role of oncogenes in both health and disease is vital for developing new cancer therapies and potentially even anti-aging strategies.

1. VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR–PI3K–AKT pathway (oncogene,(2018), 37, 41,(5585 …
2. … and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation
3. … and hormonal aspects of 6 human neoplasias with special emphasis on the presentation of the topological features of oncogene activation tumor suppressor gene …
4. … associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation
5. … b-lineage proto-oncogene b–deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance
6. … chemically induced ha‐ras mutation and transformation of BALB/c 3T3 cells: Evidence for chemical‐specific activation and cell type—specific recruitment of oncogene …
7. … coffee intake and serum concentrations of some organochlorine compounds are independently associated with the mutational activation of the K-ras oncogene.
8. … energy particle radiation-associated oncogenic transformation in normal mice: insight into the connection between activation of oncotargets and oncogene …
9. … Epstein–Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases
10. … of chlordane in B6C3F1 and B6D2F1 male mice: evidence for regression in B6C3F1 mice and carcinogenesis independent of ras proto-oncogene activation
11. … of CXC chemokines, growth-related oncogene α expression, and epithelial cell-derived neutrophil-activating protein-78 by ML-1 (interleukin-17F) involves activation …
12. … of the chemokines monocyte chemotactic protein-1, regulated on activation normal T cell expressed and secreted protein, growth-related oncogene, and interferon-γ …
13. … Overexpression of the Wild-Type Gsα as the gsp oncogene Initiates Chronic Extracellularly Regulated Kinase 1/2 Activation and Hormone Hypersecretion in Pituitary …
14. … pathway in response to human papillomavirus infection and over‐expressionof interleukin‐32 controls the expression of the humanpapillomavirus oncogene
15. … pathway through F‐actin: F‐Actin, assembled in response to Galpha12/13 induced RhoA‐GTP, promotes dephosphorylation and activation of the YAP oncogene
16. … T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene
17. 1O Double PIK3CA mutations in cis enhance PI3Kα oncogene activation and sensitivity to PI3Kα inhibitors in breast cancer
18. 291. A Novel Safety Assay for Retroviral Vectors That Reproduces Lmo2 Proto-oncogene Insertional Activation Events
19. A complex containing PBX2 contributes to activation of the proto-oncogene HOX11
20. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene
21. A human cellular sequence implicated in trk oncogene activation is DNA damage inducible.
22. A new mechanism of oncogenic activation: E26 retroviral v-ets oncogene has inverted the C-terminal end of the transcription factor c-ets-1
23. A repetitive element containing a critical tyrosine residue is required for transcriptional activation by the EWS/ATF1 oncogene
24. A role for substance P in cancer promotion and progression: a mechanism to counteract intracellular death signals following oncogene activation or DNA damage
25. A role for Z-DNA in transcriptional activation of the human c-myc oncogene by the vaccinia virus E3L protein
26. A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C.
27. A signal transduction pathway for activation of the mdr1 promoter involves the proto-oncogene c-raf kinase.
28. A study on the activation of oncogene and inactivation of suppressor gene in human gastric cancer
29. A study on the activation of oncogene and inactivation of suppressor gene in human gastric cancer
30. Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic
31. Aberrant splicing events that are induced by proviral integration: implications for myb oncogene activation
32. Abl oncogene bypasses normal regulation of Jak/STAT activation
33. Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs.
34. Absence of Kirsten-ras oncogene activation in B-cell chronic lymphocytic leukemia
35. Absence of ras oncogene activation in rat urinary bladder carcinomas induced by N-methyl-N-nitrosourea or N-butyl-N(4-hydroxybutyl)nitrosamine
36. Abstract A08: Fast and efficient generation of conditional ROSA26-based mouse models that recapitulate oncogene activation in T-cell acute lymphoblastic leukemia
37. Abstract A43: TFG-TEC oncogene modulates beta-enolase expression via both promoter activation and epigenetic modification
38. Abstract B22: oncogene activation of K‐ras in resident myofibroblasts leads to development of spontaneous bronchioalveolar carcinoma in mice
39. Abstract C131: HSP27 is necessary in cells showing oncogene hyper-activation.
40. Abstract LB-128: The N-terminus of the ASPP2 tumor suppressor binds Ras and enhances Ras/Raf/MEK activation to promote oncogene-induced cellular senescence
41. Abstract P1-06-05: Mre11 mediates a p53-independent quiescence program in response to mammary oncogene activation
42. Abstract P6-03-04: Amplification of the WHSC1L1 oncogene regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is …
43. Abstract# 4928: Impact of the targeted activation of the PLAG1 proto-oncogene in salivary glands, mammary glands, adipose tissue and pancreas of PLAG1 …
44. Activation and expression of the K-ras oncogene in mouse lung tumorigenesis.
45. Activation and Specificity of Aflatoxin B1 Binding on hhcM, a Human oncogene of Low Efficiency, and Cell Transformation
46. Activation mechanism of the N-ras oncogene in human leukemias detected by synthetic oligonucleotide probes
47. Activation of a cellular oncogene (c-mos) by DNA transposition
48. ACTIVATION OF A CELLULAR oncogene (C-MOS) BY DNA TRANSPOSITION.
49. Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element
50. Activation of a cellular proto-oncogene in spontaneous liver tumor tissue of the B6C3F1 mouse
51. Activation of a cK-ras oncogene by somatic mutation in mouse lymphomas induced by gamma radiation
52. Activation of a mcf. 2 oncogene by deletion of amino-terminal coding sequences.
53. Activation of a muscle-specific enhancer by the Ski proto-oncogene
54. Activation of a novel proto‐oncogene, Frat1, contributes to progression of mouse T‐cell lymphomas
55. Activation of anthraquinone biosynthesis in long-cultured callus culture of Rubia cordifolia transformed with the rolA plant oncogene
56. Activation of c-Ha-ras proto-oncogene by in vitro chemical modification with 2-amino-6-methyldipyrido [1, 2-a: 3′, 2′-d] imidazole (Glu-P-1) and 4-nitroquinoline N-oxide …
57. Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo (a) pyrene diol-epoxide
58. Activation of c-mos oncogene by integration of an endogenous long terminal repeat element during transfection of genomic DNA from mouse skin tumor cells.
59. Activation of CCND1 oncogene in nasopharyngeal carcinoma
60. Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2
61. Activation of cellular oncogenes in human and mouse leukemia-lymphomas: spontaneous and induced oncogene expression in murine B lymphocytic neoplasms
62. Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat.
63. Activation of Expression of the c‐fos oncogene by UVA Irradiation in Cultured Human Skin Fibroblasts
64. Activation of fibroblast growth factor receptor 3 and oncogene‐induced senescence in skin tumours
65. Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene
66. Activation of H- ras oncogene in 3-methylcholanthrene-transformed human cell line
67. Activation of H-ras oncogene in Rat Bladder Tumors Induced by N-Butyl-N-(4-hydroxybutyl)nitrosamine1
68. Activation of Harvey ras oncogene by mutation at codon 12 is very rare in hemopoietic malignancies.
69. Activation of heat shock protein (hsp) 70 and proto-oncogene expression by alpha1 adrenergic agonist in rat aorta with age.
70. Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL
71. Activation of human papillomavirus type 18 E6–E7 oncogene expression by transcription factor Sp1
72. Activation of IL-2 receptor alpha-chain gene by individual members of the rel oncogene family in association with serum response factor.
73. Activation of Mas oncogene-Related G Protein–Coupled Receptors Inhibits Neurochemical Alterations in the Spinal Dorsal Horn and Dorsal Root Ganglia Associated …
74. Activation of Mas oncogene-related gene (Mrg) C receptors enhances morphine-induced analgesia through modulation of coupling of μ-opioid receptor to Gi-protein …
75. Activation of mouse osteoblast growth hormone receptor: c-fos oncogene expression independent of phosphoinositide breakdown and cyclic AMP
76. Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B
77. Activation of multiple oncogene pathways: a model for experimental carcinogenesis
78. Activation of N-myc oncogene and associated genes to chemoresistance, prognostic value for neuroblastoma
79. Activation of nuclear factor kappa B and oncogene expression by 12 (R)-hydroxyeicosatrienoic acid, an angiogenic factor in microvessel endothelial cells.
80. Activation of oncogene c‐Ha‐ras in gastric cancer of chinese patients
81. Activation of oncogene expression in psoriatic lesions
82. Activation of oncogenicity of the c-rel proto-oncogene.
83. Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants.
84. Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains
85. Activation of protease‐activated receptors in astrocytes evokes a novel neuroprotective pathway through release of chemokines of the growth‐regulated oncogene …
86. Activation of proto-oncogene c-fos in the auditory tract of rats stimulation with wide-band noise
87. Activation of proto-oncogene expression by growth regulatory signals
88. Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors
89. Activation of ras oncogene in aflatoxin-induced rat liver carcinogenesis
90. Activation of ras oncogene in livers with cirrhosis
91. Activation of ras oncogene in myelodysplastic syndrome and acute myelogenous leukemia
92. Activation of specific glutamate receptor subtypes increases c-fos proto-oncogene expression in primary cultures of neonatal rat cerebellar granule cells
93. Activation of spinal MrgC-Gi-NR2B-nNOS signaling pathway by Mas oncogene-related gene C receptor agonist bovine adrenal medulla 8-22 attenuates bone …
94. Activation of the abl oncogene and its involvement in chromosomal translocations in human leukemia
95. Activation of the abl oncogene in murine and human leukemias
96. Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties.
97. Activation of the c-fos Proto-oncogene in the Spinal Cord Following Noxious Stimulation of the Urinary Bladder
98. Activation of the c-Ki-ras oncogene in aflatoxin B1-induced hepatocellular carcinoma and adenoma in the rat: detection by denaturing gradient gel electrophoresis.
99. Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome
100. Activation of the c-myc oncogene
101. Activation of the c-myc oncogene by the immunoglobulin heavy-chain gene enhancer after multiple switch region-mediated chromosome rearrangements in a murine …
102. Activation of the c-myc oncogene in a Precursor-B-Cell Blast Crisis of Follicular Lymphoma, Presenting as Composite Lymphoma
103. Activation of the c-myc oncogene in B and T lymphoid tumors
104. Activation of the c-ski oncogene by overexpression.
105. Activation of the c‐Ha‐ras‐1 proto‐oncogene by methylation in vitro with α‐acetoxy‐N‐nitrosodimethylamine
106. Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus
107. Activation of the cellular proto-oncogene product p21Ras by addition of a myristylation signal
108. Activation of the cH-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.
109. Activation of the cK-ras oncogene in a human pancreas carcinoma
110. Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene
111. Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype
112. Activation of the GLI oncogene through fusion with the β-actin gene (ACTB) in a group of distinctive pericytic neoplasms: pericytoma with t (7; 12)
113. Activation of the H-ras oncogene in hepatocellular carcinomas initiated with diethylnitrosamine and promoted by a dietary methyl deficiency
114. Activation of the Ha-ras oncogene in tumors induced in mice by transplacental exposure to 7, 12-dimethylbenz (a) anthracene
115. Activation of the human c-Ha-ras-1 proto-oncogene by in-vitro reaction with N-nitrosomethyl (acetoxymethyl) amine.
116. Activation of the JNK pathway is essential for transformation by the Met oncogene
117. Activation of the K-ras oncogene in liver tumors of Hudson River tomcod
118. Activation of the K‐ras oncogene in colorectal neoplasms is Associated with decreased apoptosis
119. Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting
120. Activation of the M-CSF gene in mouse macrophages immortalized by retroviruses carrying a v-myc oncogene.
121. Activation of the mas oncogene during transfection of monoblastic cell line DNA.
122. Activation of the mas oncogene involves coupling to human alphoid sequences.
123. Activation of the met oncogene in the human MNNG-HOS cell line involves a chromosomal rearrangement
124. Activation of the met Proto-oncogene in
125. Activation of the met Proto-oncogene in a Human Cell Line
126. Activation of the N-myc2 oncogene by woodchuck hepatitis virus integration in the linked downstreamb3nLocus in woodchuck hepatocellular carcinoma
127. Activation of the Na+/H+-exchanger is NIH 3T3 fibroblasts expressing the Ha-ras oncogene requires stimulated calcium influx and is associated with rearrangement of …
128. Activation of the oncogene ERG by the Ras/ERK and PI3K/AKT pathways
129. Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis
130. Activation of the proto-oncogene c-myc and c-fos by c-ras: involvement of polyamines
131. Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain.
132. Activation of the ras oncogene and its relationship to aflatoxins-DNA adduct formation in the rat liver treated with aflatoxins
133. Activation of the receptor kinase domain of the trk oncogene by recombination with two different cellular sequences.
134. Activation of the ret oncogene in human thyroid carcinomas
135. Activation of the ret-II oncogene without a sequence encoding a transmembrane domain and transforming activity of two ret-II oncogene products differing in carboxy …
136. Activation of the T-Cell oncogene LMO2 after Gene Therapy for X-Linked Severe Combined Immunodeficiency
137. Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos …
138. Activation of the trk oncogene by alternatively spliced muscle and non-muscle tropomyosin sequences.
139. Activation of the Xmrk proto-oncogene of Xiphophorus by overexpression and mutational alterations
140. Activation of transcription of the melanoma inducing Xmrk oncogene by a GC box element
141. Activation of v‐Myb avian myeloblastosis viral oncogene homolog‐like2 (MYBL2)‐LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of …
142. Agent-specific ras oncogene activation in rat thyroid tumours.
143. AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability
144. Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer
145. Alkylating agent-induced mutagenesis and activation of the Ha-ras oncogene
146. Alpha 1 adrenergic receptor activation of proto-oncogene expression in arterial smooth muscle: regulation by nitric oxide and vascular injury.
147. Amplification and activation of c-Ki-ras oncogene in cell line developed from human pancreas explants.
148. Amplification of the proto-neu oncogene facilitates oncogenic activation by a single point mutation
149. An analysis of oncogene activation in ovarian carcinoma
150. An atypical t(12;15) translocation of chromosomes found in murine plasmacytomas and activation of the c‐myc oncogene
151. An experimental model for oncogene activation during tumor progression in vivo.
152. An hsRPB4/7-dependent yeast assay for trans-activation by the EWS oncogene
153. Analysis of the activation of the myc family oncogene and of its stability over time in xenografted human lung carcinomas
154. Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma.
155. Angiogenesis Correlates with Vascular Endothelial Growth Factor Expression but not with Ki-ras oncogene Activation in Non-Small Cell Lung Carcinoma1
156. Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling
157. Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain
158. Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early …
159. Assessment of RET/PTC oncogene activation in thyroid nodules utilizing laser microdissection followed by nested RT-PCR
160. Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway
161. Atypical mechanism of NF-κB activation by TRE17/ubiquitin-specific protease 6 (USP6) oncogene and its requirement in tumorigenesis
162. B‐raf oncogene: Activation by Rearrangements and Assignment to Human Chromosome 7
163. bcr-abl oncogene activation in Philadelphia chromosome-positive acute lymphoblastic leukemia.
164. Blaydes, JP et al. Synergistic activation of p53-dependent transcription by two cooperating damage recognition pathways. oncogene 19, 3829-3839
165. BRCA1 chromatin dissociation induced by oncogene activation promotes formation of senescence-associated heterochromatin foci and senescence via chromatin …
166. c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene
167. c‐fos proto‐oncogene expression in human NK/LGL cells: Expression is not constitutive and is associated with functional activation
168. C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin A expression and alterations of …
169. CAMAL: a new prognostic marker for remission in acute nonlymphoblastic leukemia Absence of kirsten-ras oncogene activation in B-cell chronic lymphocytic leukemia …
170. Can oncogene (RAS) activation predict susceptibility of human melanoma to activated lymphocytes and, therefore, the clinical response of such neoplasms to …
171. Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation
172. Carcinogenic metalloid arsenic induces expression of mdig oncogene through JNK and STAT3 activation
173. Carcinogenicity, metabolism and Ki-ras proto-oncogene activation by 7, 12-dimethylbenz[a] anthracene in rainbow trout embryos
174. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
175. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
176. Cell type-specific E2F activation and cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I
177. Cell type‐specific conditional regulation of the c‐myc proto‐oncogene by combining Cre/loxP recombination and tamoxifen‐mediated activation
178. Cellular analysis of the kinetics of alpha-fetoprotein and nuclear oncogene activation in primary cultures of adult rat hepatocytes stimulated by epidermal growth factor
179. Cellular oncogene activation
180. Cellular oncogene Activation by Chromosomal Translocation
181. Cellular oncogene activation by human cytomegalovirus lack of correlation with virus infectivity and immediate early gene expression
182. Cellular oncogene activation: edited by George Klein, Marcel Dekker, 1988. $110.00 (USA and Canada), $132.00 (elsewhere)(xv+ 396 pages) ISBN 0 8247 7983 5
183. Centrosome aberrations and spindle defects in thyroid carcinoma cells harboring specific oncogene activation
184. Characterization of the mouse transforming growth factor-beta 1 promoter and activation by the Ha-ras oncogene.
185. CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E-cadherin
186. Chromatin Alterations in a Model of oncogene Activation Studied by Advanced Fluorescence Microscopy
187. Chromosome abberation and oncogene activation in two histologically related human and rat B-cell tumors
188. Chromosome Break-Points, Somatic Mutation and oncogene Activation: Some Comments
189. Chromosome rearrangements and oncogene activation in thyroid tumors
190. Chromosome translocations and the activation of C-myc oncogene in mouse plasmacytomas
191. Clinical implications of oncogene activation in human neuroblastomas
192. Clinical significance of K-ras oncogene activation in ampullary neoplasms.
193. Clinical significance of ras oncogene activation in human lung cancer
194. ClinicI significance of ras oncogene activation in human hmg cancer
195. Cloning and activation of the Syrian hamster neu proto-oncogene
196. Cloning of the murine c-fgr proto-oncogene cDNA and induction of c-fgr expression by proliferation and activation factors in normal bone marrow-derived monocytic …
197. Colony stimulating factor‐1 (CSF‐1) stimulates temperature dependent phosphorylation and activation of the RAF‐1 proto‐oncogene product.
198. Combating oncogene activation associated with retrovirus-mediated gene therapy of X-linked severe combined immunodeficiency
199. Comparison of K‐ras oncogene Activation in Pancreatic Duct Carcinomas and Cholangiocarcinomas Induced in Hamsters by N‐Nitrosobis(2‐hydroxypropyl)amine
200. Complement activation causes oncogene expression in Gaucher disease
201. Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene
202. Conditional deletion of Pten tumor suppressor gene and activation of K-Ras oncogene result in the development of Neurofibromatoses
203. Constitutive activation of a variant of the env-mpl oncogene product by disulfide-linked homodimerization.
204. Constitutive activation of stat 3 oncogene product in human ovarian carcinoma cells
205. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia.
206. Constitutive macropinocytosis in oncogene-transformed fibroblasts depends on sequential permanent activation of phosphoinositide 3-kinase and phospholipase C
207. Contribution of the activation of the ras oncogene to the evolution of aldosterone-and renin-secreting tumors.
208. Correlation of Thyroid Hormone Dose-dependent Regulation of K-ras Protoncogene Expression with oncogene Activation by 3-Methylcholanthrene: Loss of Thyroidal …
209. Correlations of morphology, proliferation indices, and oncogene activation in ductal breast carcinoma: nuclear grade, S-phase, proliferating cell nuclear antigen, p53 …
210. Correspondence re: G. Tallini et al., RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly …
211. COT Kinase Proto-oncogene Expression in T Cells IMPLICATION OF THE JNK/SAPK SIGNAL TRANSDUCTION PATHWAY INCOT PROMOTER ACTIVATION
212. CRISPR/Cas9-Based Approaches for Investigating Mechanisms of oncogene Activation and Tumor Suppression
213. DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation
214. Deletion variants within the NF-kappaB activation domain of the LMP1 oncogene in acquired immunodeficiency syndrome-related large cell lymphomas, in …
215. Deletion Variants within the NF-kB Activation Domain of the LMP1 oncogene in Acquired Immunodeficiency Syndrome-Related Large Cell Lymphomas, in …
216. Deletion Variants Within the NF-KB Activation Domain of the LMPl oncogene Prevail in Acquired Immunodeficiency Syndrome-Related Large Cell Lymphomas …
217. DELETIONS AND MUTATIONS WITHIN THE NF-κB ACTIVATION DOMAIN OF THE LATENT MEMBRANE PROTEIN 1 (LMP1) oncogene OCCUR DURING LONG …
218. DELETIONS AND MUTATIONS WITHIN THE NF-κB ACTIVATION DOMAIN OF THE LATENT MEMBRANE PROTEIN 1 (LMP1) oncogene OCCUR DURING LONG …
219. Demonstration of cytogenesis of pancreas ductal carcinomas by conditional activation of mutated human Ha-ras oncogene in vivo in the rat
220. Desmoglein 3 acts as a potential oncogene in promoting cancer cell migration and invasion through regulating AP-1 and PKC dependent-Ezrin activation
221. Detection of K-ras oncogene activation in human lung cancer and its possible clinical application
222. Detection of RET oncogene activation in human papillary thyroid carcinomas by in situ hybridisation
223. Development of multidrug resistance due to multiple factors including P‐glycoprotein overexpression under K‐selection after MYC and HRAS oncogene activation
224. Diagnosis of papillary thyroid carcinoma is facilitated by using an RT-PCR approach on laser-microdissected archival material to detect RET oncogene activation
225. Dietary fatty acids regulate the activation status of Her-2/neu (c-erbB-2) oncogene in breast cancer cells
226. Different mechanisms are responsible for oncogene activation in human mammary neoplasia
227. Differential activation of the c-Ki-ras-2 proto-oncogene in human colorectal carcinoma.
228. Differential Activity of the KRAS oncogene by Method of Activation: Implications for Signaling and Therapeutic Intervention
229. Direct trans-activation of the human cyclin D2 gene by the oncogene product Tax of human T-cell leukemia virus type I
230. DNA amplification is a common mechanism of oncogene activation in lung cancer
231. DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers
232. DNA Damage Response and Genetic Instability; AIMP3 Haploinsufficiency inhibit p53 activation by oncogene including Ras and c-myc, result to Genomic instability
233. Dominant-negative Rac1 suppresses Ras-induced apoptosis possibly through activation of NFκB in Ha-ras oncogene-transformed NIH/3T3 cells
234. Dose dependency of aflatoxin B1 binding on human high molecular weight DNA in the activation of proto-oncogene.
235. Dose-dependent activation of putative oncogene SBSN by BORIS
236. Dose-dependent carcinogenicity and frequent Ki-ras proto-oncogene activation by dietary N-nitrosodiethylamine in rainbow trout
237. Double PIK3CA mutations in cis enhance oncogene activation and sensitivity to PI3K alpha inhibitors in breast cancer
238. Down-regulation of lysyl oxidase-induced tumorigenic transformation in NRK-49F cells characterized by constitutive activation of ras proto-oncogene
239. Drosophila actin-Capping Protein limits JNK activation by the Src proto-oncogene
240. Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells
241. Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha- ras oncogene in rat pancreas
242. E2F1 induction following DNA damage and oncogene activation
243. Early activation of the proto-oncogene c-fgr during Epstein-Barr virus immortalization
244. Early biochemical markers of effects: enzyme induction, oncogene activation and markers of oxidative damage
245. Early biochemical markers of effects: enzyme induction, oncogene activation and markers of oxidative damage
246. Early effects of transplatin on oncogene activation in vivo
247. Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma
248. Effect of activation of HOX11 proto-oncogene on prognosis of acute leukemia in children [J]
249. Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells.
250. Effects of v-src oncogene Activation on Radiation Sensitivity in Drug-Sensitive and in Multidrug-Resistant Rat Fibroblasts
251. EGF promotes development of a differentiated trophoblast phenotype having c-myc and junB proto-oncogene activation
252. ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation
253. Epigenetic activation of WHSC1 functions as an oncogene and is associated with poor prognosis in cervical cancer
254. Establishment of Murine Lung Alveolar Epithelial Cell Lines from Lung Tumors Initiated by Somatic Activation of the K-ras oncogene.
255. Ets and retroviruses–transduction and activation of members of the Ets oncogene family in viral oncogenesis
256. ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex
257. Evaluating the safety of retroviral vectors based on insertional oncogene activation and blocked differentiation in cultured thymocytes
258. Evidence for long‐range oncogene activation by hepadnavirus insertion.
259. Evidence that the ras oncogene-encoded p21 protein induces oocyte maturation via activation of protein kinase C.
260. Expression of FLJ10540, a novel oncogene, is associated with liver carcinogenesis and tumor progression through the activation of PKB/AKT pathway
261. Expression of major histocompatibility class I genes in differentiating leukemic cells is temporally related to activation of c-fos proto-oncogene.
262. Expression of the Bcl-3 proto-oncogene suppresses p53 activation
263. Expression, Function and Activation of the Proto-oncogene c-kit Product in Human Leukemia Cells
264. Extremely stringent activation of p16INK4a prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression
265. Fastest Time to Cancer by Loss of Tumor Suppressor Genes or oncogene Activation
266. Felis catus papillomavirus type 2 E6 oncogene enhances mitogen-activated protein kinases and Akt activation but not EGFR expression in an in vitro feline model of …
267. Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha
268. Follicle-stimulating hormone induces multiple signaling cascades: evidence that activation of Rous sarcoma oncogene, RAS, and the epidermal growth factor receptor …
269. Frequent activation of the Ki‐ras oncogene at codon 12 in N‐methyl‐N‐nitrosourea‐induced rat prostate adenocarcinomas and neurogenic sarcomas
270. Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation
271. Frequent multiple c‐ki‐ras oncogene activation in pancreatic juice from patients with benign pancreatic cysts
272. Function-dependent cooperation between oncogene activation and nonrandom chromosome change during tumorigenic conversion of Syrian hamster cells
273. Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes
274. Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas
275. Genome-wide examination of topological variability reveals cell type-specific mechanisms of oncogene activation
276. Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer
277. Genomic effects of the putative oncogene G alpha s. Chronic transcriptional activation of the c-fos proto-oncogene in endocrine cells.
278. GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer
279. Growth factor biology and oncogene activation in human gliomas and their implications for specific therapeutic concepts
280. Growth, differentiation, and malignant transformation of pre-B cells mediated by inducible activation of v-Abl oncogene
281. GTPγS activation of proto‐oncogene expression in transiently permeabilised Swiss 3T3 fibroblasts
282. H-ras oncogene Activation in Invasive UVR-Induced Corneal Sarcomas of the Opossum Monodelphis domestica
283. Ha-ras oncogene activation in mammary glands of N-methyl-N-nitrosourea-treated rats genetically resistant to mammary adenocarcinogenesis.
284. Ha-ras oncogene induction of invasion and metastasis is associated with the activation and redistribution of protease (s) in rat-kidney cells
285. Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell.
286. Hepatitis B virus integration and oncogene activation
287. HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells
288. High frequency of mas oncogene activation detected in the NIH3T3 tumorigenicity assay.
289. High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis.
290. High Frequency of ras oncogene Activation in Benign and Malignant Human Thyroid Tumours
291. HIGH FREQUENCY OF!~~ oncogene ACTIVATION
292. High Iodine Concentration Attenuates RET/PTC3 oncogene Activation in Thyroid Follicular Cells
293. High prevalence of RET proto-oncogene activation (RET/PTC) in papillary thyroid carcinomas
294. High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene
295. Higher frequency of ras oncogene activation in gastric stump carcinomas due to special conditions in the gastric remnant
296. Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry
297. Homeobox oncogene activation by pan-cancer DNA hypermethylation
298. Human c-fos proto-oncogene mapped to chromosome 14, band q24. 3–q31 possibilities for oncogene activation by chromosomal rearrangements in human …
299. Hyperpolarized 13C Magnetic Resonance Spectroscopy: Probing Enzymatic Activity, Cellular Transport, and oncogene Activation
300. Hyperpolarized 13C Magnetic Resonance Spectroscopy: Probing Enzymatic Activity, Cellular Transport, and oncogene Activation
301. Hypomethylation mediated by decreased DNMTs involves in the activation of proto-oncogene MPL in TK6 cells treated with hydroquinone
302. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit …
303. In vitro activation of the human Harvey-ras proto-oncogene by aflatoxin B1.
304. In vitro activity of the EWS oncogene transcriptional activation domain
305. In vitro transformation of rat cells by 3-methylcholanthrene: activation of the ras oncogene
306. Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung
307. Incidence of ras oncogene activation in lung carcinomas in Hong Kong
308. Influence of HPV16 E7 oncogene activation on the expression of cdc25A and cyclin E in HeLa cells [J]
309. Influence of oleic acid on the expression, activation and activity of gelatinase a produced by oncogene‐transformed human bronchial epithelial cells
310. Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and upregulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced …
311. Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non–small cell lung cancer
312. Initiation factor eIF2B not p70 S6 kinase is involved in the activation of the PI‐3K signalling pathway induced by the v‐src oncogene
313. Insulator dysfunction and epigenetic oncogene activation in SDH-deficient gastrointestinal stromal tumor
314. Insulator dysfunction and oncogene activation in IDH mutant gliomas
315. Insulator dysfunction and oncogene activation in IDH mutant gliomas
316. Integration of transfected LTR sequences into the c‐raf proto‐oncogene: activation by promoter insertion.
317. Interaction between the adhesion receptor, CD44, and the oncogene product, p185 HER2, promotes human ovarian tumor cell activation
318. Interleukin-1 activation of FOS proto-oncogene protein in the rat hypothalamus
319. Intragenic recruitment of NF-κB drives alternative splicing modifications upon activation by the viral oncogene TAX of HTLV-1
320. Involvement of K-ras oncogene Activation in Formaldehyde-induced Rat Nasal Carcinoma
321. Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours
322. Isocitrate Dehydrogenase Mutation Leads to Alteration in 3-Dimensional DNA Structure and oncogene Activation in Gliomas
323. Isoform-specific ras activation and oncogene dependence during MYC-and Wnt-induced mammary tumorigenesis
324. K-ras oncogene Activation as a Prognostic Marker in Adenocarcinoma of the Lung
325. K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction …
326. K-ras oncogene activation in atypical alveolar hyperplasias of the human lung
327. K-ras oncogene Activation in Neoplasias of Patients with Familial Adenomatous Polyposis or Kidney Transplant
328. K‐ras oncogene activation in lung adenocarcinomas from former smokers evidence that K‐ras mutations are an early and irreversible event in the development of …
329. Ki-ras oncogene activation in preinvasive pancreatic cancer
330. Ki-ras oncogene activation in transplantable rat thyroid carcinoma induced by N-bis (2-hydroxypropyl) nitrosamine
331. Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade.
332. LINC01857 as an oncogene regulates CREB1 activation by interacting with CREBBP in breast cancer
333. Lineage-Specific Epigenomic and Genomic Activation of the oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas
334. Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation
335. Long-range effects of direct-hit ultraviolet and particle radiation in oncogene activation.
336. Loss of Retinoic Acid Receptors in Mouse Skin and Skin Tumors Is Associated with Activation of the ras―@ oncogene and High Risk for Premalignant …
337. Loss of retinoic acid receptors in mouse skin and skin tumors is associated with activation of the rasHa oncogene and high risk for premalignant progression
338. Low frequency of detectable oncogene activation in rat liver and mammary tumors induced by a single dose of diethylnitrosamine and continuous treatment with 17 …
339. Low incidence of ras oncogene activation in human squamous cell carcinomas
340. Low rate of ret proto‐oncogene activation (PTC/retTPC) in papillary thyroid carcinomas from saudi arabia
341. Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
342. Mastoparan transiently permeabilises Swiss 3T3 cells and induces c-fos proto-oncogene expression: Role of calcium and G protein activation
343. Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats
344. Mechanism of activation and biological role of the c-myc oncogene in B-cell lymphomagenesis
345. Mechanism of activation of a human oncogene
346. Mechanism of activation of a human oncogene
347. Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells
348. Mechanism of activation of the human trk oncogene.
349. Mechanism of activation of the mouse c‐mos oncogene by the LTR of an intracisternal A‐particle gene.
350. Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations.
351. Mechanism of activation of thec-myc oncogene in Burkitt lymphoma: Structural and functional characterization of the 5’region ofc-myc.
352. Mechanism of estrogen activation of c-myc oncogene expression.
353. Mechanism of H-ras oncogene activation in mouse squamous carcinoma induced by an alkylating agent
354. Mechanism of met oncogene activation
355. Mechanism of oncogene Activation or Antioncogene Inactivation by External Factors
356. Mechanism of oncogenesis and activation of oncogene in human ovarian carcinoma
357. Mechanism of transcriptional activation by the proto-oncogene Twist1
358. Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist.
359. Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes
360. MEK kinase 1 mediates the antiapoptotic effect of the Bcr-Abl oncogene through NF-κB activation
361. met oncogene activation qualifies spontaneous canine osteosarcoma as a suitable pre‐clinical model of human osteosarcoma
362. Metabolic targeting of oncogene MYC by selective activation of the proton-coupled monocarboxylate family of transporters
363. Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells.
364. MMTV-cre-mediated fur inactivation concomitant with PLAG1 proto-oncogene activation delays salivary gland tumorigenesis in mice
365. MNU-induced point mutation and activation of c-Ha-ras oncogene in cell lines derived from human pancreas explants.
366. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15
367. Modes of c-myc oncogene activation in murine plasmacytomas
368. Molecular and biochemical bases for activation of the transforming potential of the proto-oncogene c-ros.
369. Molecular Genetic Alterations such as oncogene Activation as a Tool for the Evaluation of Risks in Chemical Carcinogenesis
370. Molecular Genetics of oncogene Activation and Gene Loss in Carcinogen-Induced Animal Tumours
371. Molecular mechanism of estrogen activation of c-myc oncogene expression in human breast cancer cells
372. Molecular mechanism of the activation of the ret/ptc1 oncogene in papillary thyroid carcinomas and characterization of the promoter of the rat sodium iodide …
373. Molecular mechanisms of cadmium carcinogenesis: The potential roles of lipid peroxidation, oncogene activation and metallothionein expression
374. Molecular mechanisms of oncogene-induced inflammation and inflammation-sustained oncogene activation in gastrointestinal tumors: An underappreciated symbiotic …
375. Mouse c-mos oncogene activation is prevented by upstream sequences
376. Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene
377. Multiple mechanisms of oncogene activation in viral and nonviral neoplasia
378. Multiple oncogene activation in a radiation carcinogenesis model
379. Multistep Scenarios in Tumor Development and the Role of oncogene Activation by Chromosomal Translocations
380. Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding.
381. Mutational activation of c-Ha-ras oncogene or cancer promotion by phenobarbital upregulates the transcription of c-jun and c-myc oncogene in N-nitrosodiethylamine …
382. Mutational activation of H-ras oncogene transformability by alkylnitrosourea-induced DNA damage
383. Mutational activation of k-ras oncogene in human breast-tumors
384. Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine
385. Mutational Activation of the K-ras oncogene
386. Mutational activation of the K-ras oncogene and the effect of chemotherapy in advanced adenocarcinoma of the lung: a prospective study.
387. Mutational activation of the β-catenin proto-oncogene is a common event in the development of Wilms’ tumors
388. Myc oncogene activation in B and T lymphoid tumours
389. N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence
390. N–methyl-d-aspartate receptors mediate activation of the c-fos proto-oncogene in a model of brain injury
391. N-Nitrosocimetidine as an initiator of murine skin tumors with associated H-ras oncogene activation
392. Nanoscale ChIP-seq analysis in primary hepatocellular carcinoma tissues reveals tumor-specific chromatin deregulation for oncogene activation
393. New knowledge on the molecular mechanism of activation of oncogenes and effect of oncogene DNA on protein synthesis
394. Nucleotide sequence of chicken c-myb complementary DNA and implications for myb oncogene activation
395. Nucleotide sequence of testis-derived c-abl cDNAs: implications for testis-specific transcription and abl oncogene activation
396. oncogene activation
397. oncogene activation and apoptosis as possible mechanism of antitumour effect of ferric-sorbitol-citrate
398. oncogene activation and breast cancer progression
399. oncogene activation and expression during carcinogenesis in liver and pancreas
400. oncogene activation and hepatocarcinogenesis
401. oncogene Activation and Human Cancer
402. oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer
403. oncogene activation and surface markers in mouse lymphomas induced by radiation and nitrosomethylurea
404. oncogene activation and tumor suppressor gene inactivation during multistage mouse skin carcinogenesis
405. oncogene activation and tumor suppressor gene inactivation find their sites of expression in the changes in time and space of the age-adjusted cancer incidence rate.
406. oncogene activation as a prognostic marker in head and neck cancer
407. oncogene activation by chromosomal rearrangement in chronic myelocytic leukemia
408. oncogene activation by chromosomal translocation in chronic myelocytic leukemia
409. oncogene activation by chromosomal translocations
410. oncogene activation by chromosomal translocations in B cell-derived tumors
411. oncogene activation by chromosome translocation
412. oncogene activation by chromosome translocation in human malignancy
413. oncogene activation during multi-stage carcinogenesis
414. oncogene activation during radiation induced transformation in vitro
415. oncogene activation in astrocytic neoplasms
416. oncogene activation in chemical carcinogenesis
417. oncogene ACTIVATION IN CHEMICALLY INDUCED RAT NASAL TUMORS
418. oncogene activation in esophageal cancer
419. oncogene activation in experimental carcinogenesis: the role of carcinogen and tissue specificity.
420. oncogene activation in human benign tumors of the skin (keratoacanthomas): is HRAS involved in differentiation as well as proliferation?
421. oncogene activation in human myeloid leukemia
422. oncogene activation in malignant transformation: a study of H-ras in human breast cancer
423. oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence
424. oncogene Activation in Multistage Carcinogenesis
425. oncogene activation in myeloid leukemias by Graffi murine leukemia virus proviral integration
426. oncogene activation in pituitary tumors
427. oncogene activation in radiation-induced lung tumours
428. oncogene activation in radiation-induced rat skin tumors
429. oncogene activation in rheumatoid synovium
430. oncogene activation in spontaneous and chemically induced rodent tumors: implications for risk analysis.
431. oncogene activation in the leukemias
432. oncogene Activation in Xeroderma Pigmentosum Skin Tumors
433. oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells
434. oncogene activation of HIV-LTR-driven expression via the NF-ϰB binding sites
435. oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway.
436. oncogene activation: an informative marker for the human papillomavirus-lesions severity.
437. oncogene activation: c-raf-1 gene mutations in experimental and naturally occurring tumors
438. oncogene activation: Message of myc in context
439. oncogene and tissue specific pathway activation in an HER2 dependent mouse mammary tumor model
440. oncogene cooperativity in Friend erythroleukemia: erythropoietin receptor activation by the env gene of SFFV leads to transcriptional upregulation of PU. 1 …
441. oncogene expression in small‐cell lung cancer cell lines and a testicular germ‐cell tumor: Activation of the N‐myc gene and decreased RB mRNA
442. oncogene involvement in tumor regression: H-ras activation in the rabbit keratoacanthoma model.
443. oncogene pathway activation in mammary tumors dictates FDG-PET uptake
444. oncogene regulation of endonuclease activation in apoptosis
445. oncogene transduction and activation.
446. oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system
447. oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
448. oncogene-induced up-regulation of Caco-2 cell proliferation involves IGF-II gene activation through a protein kinase C-mediated pathway
449. oncogene-specific activation of tyrosine kinase networks during prostate cancer progression
450. Oncogenic activation of the human trk proto‐oncogene by recombination with the ribosomal large subunit protein L7a.
451. Oncogenic activation of the tyrosine kinase domain of the human trk proto-oncogene by fusion to a cell adhesion molecule.
452. Overexpression of human proto-oncogene DEK induces apoptosis in drosophila by histone modification and caspase activation
453. Overexpression of the N-ras proto-oncogene, not somatic mutational activation, associated with malignant tumors in transgenic mice.
454. Overexpression of the novel oncogene SALL4 and activation of the Wnt/β-catenin pathway in myelodysplastic syndromes
455. Overrunning cellular replicative capacities, through telomere maintenance or oncogene activation, alters epigenetic profiles
456. P53 and radiation response. The impact of oncogene activation in oesophagus carcinoma treated by radiotherapy only
457. Parathyroid Hormone‐Related Protein Regulates Glioma‐Associated oncogene Transcriptional Activation: Lessons Learned from Bone Development and Cartilage …
458. Parity and Neu oncogene activation in breast cancer risk and mammary carcinogenesis
459. Pathways for activation of the ras-oncogene-encoded p21 protein
460. Patterns of oncogene activation in human neuroblastoma cells
461. Peptides genetically selected for NF-κB activation cooperate with oncogene Ras and model carcinogenic role of inflammation
462. Pharmacologic activation of REV-ERBs is lethal in cancer and oncogene-induced senescence
463. Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence
464. PHD2 acts as an oncogene through activation of Ras/Raf/MEK/ERK and JAK1/STAT3 pathways in human hepatocellular carcinoma cells
465. Phosphofructokinases Axis Controls Glucose-Dependent mTORC1 Activation Driven by E2F1 oncogene
466. Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene.
467. Phosphorylation of E-box binding USF-1 by PI3K/AKT enhances its transcriptional activation of the WBP2 oncogene in breast cancer cells
468. Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene
469. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
470. PI3K/AKT MEDIATED PHOSPHORYLATION OF USF-1 ENHANCES ITS TRANSCRIPTIONAL ACTIVATION OF WBP2 oncogene IN BREAST CANCER CELLS
471. pim-1 proto-oncogene expression in anti-CD3-mediated T cell activation is associated with protein kinase C activation and is independent of Raf-1.
472. PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.
473. Pronounced activation of protein kinase C, ornithine decarboxylase and c-jun proto-oncogene by paraquat-generated active oxygen species in WI-38 human lung …
474. Protein kinase C regulates activation of mitogen-activated protein kinase and induction of proto-oncogene c-fos by endothelin-1.
475. Protein truncation is required for the activation of the c-myb proto-oncogene.
476. Protein tyrosine phosphatase SHP‐2: a proto‐oncogene product that promotes Ras activation
477. Proteomic analysis reveals a novel mechanism induced by the leukemic oncogene Tel/PDGFRβ in stem cells: activation of the interferon response pathways
478. Proto-oncogene activation during chemically induced hepatocarcinogenesis in rodents
479. Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice
480. Proto-oncogene activation in rodent and human tumors
481. Proto-oncogene activation in surgical specimens of rectal carcinoma.
482. Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1
483. Proviral activation of the c-myb proto-oncogene is detectable in preleukemic mice infected neonatally with Moloney murine leukemia virus but not in resulting end …
484. Proviral activation of the putative oncogene Pim‐1 in MuLV induced T‐cell lymphomas.
485. Proviral tagging in E mu‐myc transgenic mice lacking the Pim‐1 proto‐oncogene leads to compensatory activation of Pim‐2.
486. Ras oncogene activation and occupational exposures in acute myeloid leukemia
487. ras oncogene activation and the expression of ras-related genes in human lung cancer
488. ras oncogene Activation Does Not Induce Sensitivity to Natural Killer Cell-Mediated Lysis in Human Melanoma.
489. Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids
490. Ras oncogene activation in benign and malignant colorectal tumours.
491. ras oncogene activation in human ovarian carcinoma.
492. ras oncogene activation in mammary carcinomas induced by n‐methyl‐n‐nitrosourea in copenhagen rats
493. RAS oncogene activation induces proliferation in normal human thyroid epithelial cells without loss of differentiation
494. ras oncogene activation of a VL30 transcriptional element is linked to transformation.
495. Ras oncogene transformation of human B lymphoblasts is associated with lymphocyte activation and with a block of differentiation.
496. ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors.
497. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid …
498. ras proto-oncogene activation in dichloroacetic add-, trichloroethylene- and tetrachloroethylene-induced liver tumors in B6C3F1 mice
499. ras Proto-oncogene Activation in Human Malignancy
500. Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride
501. Rat c-raf oncogene activation by a rearrangement that produces a fused protein.
502. Rearrangement and Activation of a Cellular oncogene
503. Rearrangement and activation of C-MYc oncogene by chromosome translocation in B cell neoplasias
504. Recurring proviral integration suggests a role for proto-oncogene activation in thymomas induced with Mo-MuLV-rescued BCR/ABL virus
505. Regulation of proto-oncogene expression during T lymphocyte activation and proliferation
506. Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.
507. Relationship between K-ras oncogene activation and smoking in adenocarcinoma of the human lung
508. Relationship between myc oncogene activation and MHC class I expression
509. Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine …
510. Relationship between the oncogene activation profiles and the tumor suppressor gene inactivation profiles in 19 human neoplasias-a regression analysis study of the …
511. Ret and trk proto-oncogene activation in thyroid papillary carcinomas in French patients from the Champagne-Ardenne region
512. RET in papillary carcinoma of the thyroid: oncogene activation parallels nuclear changes even in “borderline” nodules
513. Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.
514. Ret oncogene activation in papillary thyroid carcinoma: prevalence and implication on the histological parameters
515. RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor …
516. RET/PTC oncogene activation is an early event in thyroid carcinogenesis.
517. Retroviral insertion and oncogene activation (current topics in microbiology and immunology, vol. 171): edited by HJ Kung and PK Vogt, Springer-Verlag; Berlin …
518. Retroviral insertional activation of the c-myb proto-oncogene in a Marek’s disease T-lymphoma cell line.
519. Retroviral insertional activation of the EVI1 oncogene does not prevent G-CSF-induced maturation of the murine pluripotent myeloid cell line 32Dcl3.
520. Retroviral insertions in the blal locus result in long-range activation of the bmil proto-oncogene in B cell lymphomas
521. Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma
522. Rgr oncogene: activation by elimination of translational controls and mislocalization
523. RNF4-dependent oncogene activation by protein stabilization
524. Role of oncogene activation during prenatal (transplacental) initiation and postnatal promotion of mouse skin tumours.
525. Role of proto-oncogene activation in carcinogenesis.
526. Role of RPB4 and RPB7 in transcriptional activation by Ewing’s sarcoma oncogene (EWS).
527. Search for Correlations between K-ras oncogene Activation and Pathology, in Sporadic and Familial Colonic Adenomas
528. Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel.
529. Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells
530. Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are …
531. Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
532. Somatic N-ras oncogene Activation in a Patient with Acute Myeloblastic Leukemia
533. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
534. Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors.
535. Specific patterns of oncogene activation in transplacentally induced tumors
536. Spi-1 oncogene activation in Rauscher and Friend murine virus-induced acute erythroleukemias.
537. Spontaneous activation of a human proto-oncogene
538. SREBP-2-driven transcriptional activation of human SND1 oncogene
539. SREBP-2-driven transcriptional activation of human SND1 oncogene
540. Step-wise progression in human skin carcinogenesis in vitro involves mutational inactivation of p53, rasH oncogene activation and additional chromosome loss.
541. STRUCTURAL ANALYSIS OF THE TRANSCRIPTIONAL ACTIVATION DOMAIN OF THE HUMAN C-MYC oncogene
542. Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET proto‐oncogene: Modeling studies
543. Structural changes of chromatin during proto-oncogene activation by cycloheximide: dose-effect
544. Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the …
545. Structure and mechanism of activation of the myb oncogene.
546. Studies of oncogene activation and tumor suppressor gene inactivation in normal and neoplastic rodent tissue
547. Studies on ras oncogene activation in endometrial carcinoma
548. Subtle distinct regulations of late erythroid molecular events by PI3K/AKT-mediated activation of Spi-1/PU. 1 oncogene autoregulation loop
549. Symposia: DNA Damage Response and Genetic Instability; AIMP3 Haploinsufficiency inhibit p53 activation by oncogene including Ras and c-myc, result to Genomic …
550. Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion
551. T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC
552. T-cell proto-oncogene rhombotin-2 is a complex transcription regulator containing multiple activation and repression domains
553. Tac2-N acts as a novel oncogene and promotes tumor metastasis via activation of NF-κB signaling in lung cancer
554. Targeted oncogene activation by site-specific recombination in transgenic mice
555. Tc-99m and Cu-64 PNA-peptide hybridization probes for imaging of oncogene activation in pancreatic cancer
556. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression
557. The coactivator oncogene AF1Q associates with STAT3 activation downstream of MET action in gastro-esophageal cancer patients
558. The Disturbance of Cell-Self-Regulation Due to oncogene Activation and Antioncogene Inactivation
559. The gep proto-oncogene Gα12 mediates LPA-stimulated activation of CREB in ovarian cancer cells
560. The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A–ARF locus in response to oncogene-and stress-induced senescence
561. The HTLV-1 latency-maintenance factor p30II activates p53-dependent metabolic effectors to promote oncogene-activation and aberrant lymphoproliferation
562. THE INFLUENCE OF DIFFERENT CLASSES OF CHEMICAL CARCINOGENS ON RAS oncogene ACTIVATION IN MURINE EPIDERMAL TUMORS.
563. The influence of point mutations in the Epstein-Barr virus LMP1 oncogene on the cell cytoskeleton and activation of inducible form of NO synthase
564. The interaction between hepatitis B virus X protein and AIB1 oncogene is required for the activation of NFκB signal transduction
565. The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation
566. The KIAA1549-BRAF fusion oncogene in pediatric low-grade gliomas undergoes in vitro paradoxical activation in response to RAF specific inhibition
567. The lack of transcriptional activation of the v-erbA oncogene is in part due to a mutation present in the DNA binding domain of the protein
568. The latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus induces expression of the putative oncogene Bcl-3 through activation of the nuclear factor-κB
569. The MYB proto-oncogene suppresses monocytic differentiation of acute myeloid leukemia cells via transcriptional activation of its target gene GFI1
570. The neural ELAVL protein HuB enhances endogenous proto-oncogene activation
571. The Observation of oncogene Activation in Transformed Cells Induced by Glass Fibers
572. The over-activation of Akt1 oncogene heightens the Glypican-3 (GPC3) effects on metastatic progression of murine mammary tumor cells
573. The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk
574. The Proto-oncogene c-myc Acts through the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1to Facilitate the Activation of Cdk4/6 and Early G1Phase Progression
575. The proto-oncogene c-src is involved in primordial follicle activation through the PI3K, PKC and MAPK signaling pathways
576. The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias.
577. The role of oncogene activation in chemical carcinogenesis
578. The role of oncogene activation in tumor progression
579. The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway
580. The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt
581. The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation.
582. The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus.
583. The Wnt-1 proto-oncogene regulates MAP kinase activation by multiple growth factors in PC12 cells.
584. The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation
585. Theoretical considerations on oncogene activation by chemical carcinogens and antioncogene inactivation by ionizing radiations: possibilities of hindrance of the …
586. Theoretical investigations on oncogene activation by chemicals and antioncogene inactivation by radiation.
587. THEORY OF oncogene ACTIVATION BY CHEMICALS AND ANTIoncogene INACTIVATION BY RADIATIONS-POSSIBLE CARCINOGENIC EFFECT OF POWER …
588. Three different activated ras genes in mouse tumours; evidence for oncogene activation during progression of a mouse lymphoma.
589. Thrombin Receptor Activation and Integrin Engagement Stimulate Tyrosine Phosphorylation of the Proto-oncogene Product, p95, in Platelets
590. Topological evidence of differential oncogene activation-tumor suppressor gene inactivation features in 10 human neoplasias, as revealed by sequential regression …
591. tpr-met oncogene product induces maturation-producing factor activation in Xenopus oocytes.
592. Trans-activation by the c-myb proto-oncogene
593. Transcriptional activation analysis of oncogene function.
594. Transcriptional activation by AP‐2α is modulated by the oncogene DEK
595. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene‐mediated apoptosis.
596. Transcriptional activation by the Ewing’s sarcoma (EWS) oncogene can be cis-repressed by the EWS RNA-binding domain
597. Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
598. Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
599. Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt
600. Transcriptional activation of c-myc proto-oncogene by estrogen in human ovarian cancer cells
601. Transcriptional activation of c-myc proto-oncogene by WT1 protein
602. Transcriptional activation of cKi-ras proto-oncogene resulting from retroviral promoter insertion
603. Transcriptional activation of gammaherpesviral oncogene promoters by the hepatitis B viral X protein (HBx)
604. Transcriptional activation of immunoglobulin α heavy-chain genes by translocation of the c-myc oncogene
605. Transcriptional activation of the c-myc oncogene in the T-47D mammary cancer cells by conditioned media from embryonic mouse fibroblasts (BALB/c-3T3). Effect of …
606. Transcriptional activation of the c-myc proto-oncogene in murine keratinocytes enhances the response to epidermal growth factor
607. Transcriptional activation of the human growth hormone gene by ras oncogene
608. Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus
609. Transcriptional activation of the proto-oncogene c-jun by asbestos and H2O2 is directly related to increased proliferation and transformation of tracheal epithelial cells
610. Transcriptional activation of the translocated c-myc oncogene in Burkitt lymphoma
611. Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: similar RNA levels in tumor and proliferating normal cells
612. Transcriptional repression of Sin3B by Bmi-1 prevents cellular senescence and is relieved by oncogene activation
613. Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer
614. Translational activation of the lck proto-oncogene
615. Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway
616. Transmembrane helix of novel oncogene with kinase-domain (NOK) influences its oligomerization and limits the activation of RAS/MAPK signaling
617. Transplacental and transgeneration carcinogenic effect of 7,12-dimethylbenz[a]anthracene: relationship with ras oncogene activation
618. TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB
619. Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process
620. Triiodothyronine (T3) upregulates the expression of proto-oncogene TGFA independent of MAPK/ERK pathway activation in the human breast …
621. Truncated glioma-associated oncogene homolog 1 (tGLI1) mediates mesenchymal glioblastoma via transcriptional activation of CD44
622. Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals
623. Two-edged sword: how activation of the “proto-oncogene” yes-associated protein 1 in lung squamous cell carcinoma can surprisingly inhibit tumor growth
624. Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor).
625. UCHL1 acts as a colorectal cancer oncogene via activation of the β-catenin/TCF pathway through its deubiquitinating activity
626. Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS
627. USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway
628. v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA
629. V-erbA oncogene, model of oncogenic activation of hormone receptor
630. v-Src oncogene induces Trop2 proteolytic activation via cyclin D1
631. V‐AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin …
632. Variant mutational activation of the K-ras oncogene in renal mesenchymal tumors induced in newborn F344 rats by methyl(methoxymethyl)nitrosamine
633. Whole-genome sequencing identified novel non-coding mutations causal of oncogene activation in T-cell acute lymphoblastic leukemia
634. α-Lipoic acid inhibits Helicobacter pylori-induced oncogene expression and hyperproliferation by suppressing the activation of NADPH oxidase in gastric epithelial …
635. α1-Adrenoceptor subtype activation increases proto-oncogene mRNA levels. Role of protein kinase C