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Nad+
Nad+
NAD+ kinase—a review
A methanol/dioxygen biofuel cell that uses NAD+-dependent dehydrogenases as catalysts: application of an electro-enzymatic method to regenerate nicotinamide …
Glyceraldehyde-3-phosphate Dehydrogenase Selectively Binds AU-rich RNA in the NAD+-binding Region (Rossmann Fold)(∗)
Activities of citrate synthase and NAD+-linked and NADP+-linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates
Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity
ADP-ribosyl cyclase: an enzyme that cyclizes NAD+ into a calcium-mobilizing metabolite.
Control of the shift from homolactic acid to mixed-acid fermentation in Lactococcus lactis: predominant role of the NADH/NAD+ ratio
Calcium ions and the regulation of NAD+-linked isocitrate dehydrogenase from the mitochondria of rat heart and other tissues
Inhibitor and NAD+ Binding to Poly(ADP-ribose) Polymerase As Derived from Crystal Structures and Homology Modeling,
The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation …
NAD+-Dependent Enzyme Electrodes: Electrical Contact of Cofactor-Dependent Enzymes and Electrodes
Prostaglandin-Metabolizing Enzymes During Pregnancy: Characterization of NAD+-Dependent Prostaglandin Dehydrogenase, Carbonyl Reductase, and …
Roles of glycerol and glycerol-3-phosphate dehydrogenase (NAD+) in acquired osmotolerance of Saccharomyces cerevisiae
A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer …
Electroreduction of NAD+ to enzymatically active NADH at poly (neutral red) modified electrodes
… of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by …
A molecular mechanics force field for NAD+ NADH, and the pyrophosphate groups of nucleotides
Causes and elimination of erratic blanks in enzymatic metabolite assays involving the use of NAD+ in alkaline hydrazine buffers: improved conditions for the assay of …
… dismutase, catalase, glutathione reductase, inorganic peroxides, TBA-reactive material, GSH/GSSG, NADPH/NADP+ and NADH/NAD+ in Drosophila melanogaster
Regulation of NAD+-linked isocitrate dehydrogenase and 2-oxoglutarate dehydrogenase by Ca2+ ions within toluene-permeabilized rat heart mitochondria. Interactions with …
Purification and properties of the NAD+-dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase
A gene encoding sn‐glycerol 3‐phosphate dehydrogenase (NAD+) complements an osmosensitive mutant of Saccharomyces cerevisiae
Purification and properties of the NAD+-xylitol-dehydrogenase from the yeast Pichia stipitis
Osmoregulation in Saccharomyces cerevisiae studies on the osmotic induction of glycerol production and glycerol 3-phosphate dehydrogenase (NAD+)
The mechanism of conversion of rat liver xanthine dehydrogenase from an NAD+-dependent form (type D) to an O2-dependent form (type O)
Utilization of Glycerol as a Hydrogen Acceptor by Lactobacillus reuteri: Purification of 1,3-Propanediol:NAD+ Oxidoreductase
NAD+ ‐dependent malic enzyme of Rhizobium meliloti is required for symbiotic nitrogen fixation
Nicotinamide adenine dinucleotide (NAD+) and related compounds. Electrochemical redox pattern and allied chemical behavior
Cloning and characterization of GPD2, a second gene encoding sn‐glycerol 3‐phosphate dehydrogenase (NAD+) in Saccharomyces cerevisiae, and its comparison …
Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols
Large supplements of nicotinic acid and nicotinamide increase tissue NAD+ and poly (ADP-ribose) levels but do not affect diethylnitrosamine-induced altered hepatic …
The effect of growth conditions on NAD+ and NADH concentrations and the NAD+: NADH ratio in normal and transformed fibroblasts
… coli K+‐uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport
Sjögren-Larsson syndrome. Deficient activity of the fatty aldehyde dehydrogenase component of fatty alcohol: NAD+ oxidoreductase in cultured fibroblasts.
NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase from Thermoproteus tenax: the first identified archaeal member of the aldehyde …
Widespread occurrence in animal tissues of an enzyme catalyzing the conversion of NAD+ into a cyclic metabolite with intracellular Ca2+-mobilizing activity
Localization of Glycerol‐3‐Phosphate Oxidase in the Mitochondrion and Particulate NAD+‐Linked Glycerol‐3‐Phosphate Dehydrogenase in the Microbodies of the Bloodstream …
Adsorption phenomena in the NAD+/NADH system at glassy carbon electrodes
NAD+ depletion and cytotoxicity in isolated hepatocytes
Klebsiella pneumoniae 1, 3-propanediol: NAD+ oxidoreductase
Reduced pyruvate decarboxylase and increased glycerol‐3‐phosphate dehydrogenase [NAD+] levels enhance glycerol production in Saccharomyces cerevisiae
Nicotinamide as a precursor for NAD+ prevents apoptosis in the mouse brain induced by tertiary-butylhydroperoxide
… IFCC methods for the measurement of catalytic concentration of enzymes. Part 8. IFCC Method for Lactate Dehydrogenase (l-Lactate: NAD+ Oxidoreductase, EC 1.1 …
Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP): prevention by the poly (ADP-ribose) polymerase …
Marcus Theory of a Parallel Effect on α for Hydride Transfer Reaction between NAD+ Analogues
Diabetes-induced glomerular dysfunction: links to a more reduced cytosolic ratio of NADH/NAD+
Transition State Structure for the Hydrolysis of NAD+ Catalyzed by Diphtheria Toxin
Reactions between diaphorase and quinone compounds in bioelectrocatalytic redox reactions of NADH and NAD+
Role of Glutamate-oxaloacetate Transaminase and Malate Dehydrogenase in the Regeneration of NAD+ for Glycine Oxidation by Spinach leaf Mitochondria
Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion
Nitric oxide toxicity in islet cells involves poly (ADP-ribose) polymerase activation and concomitant NAD+ depletion
Determinants of Cofactor Specificity in Isocitrate Dehydrogenase: Structure of an Engineered NADP+ → NAD+ Specificity-Reversal Mutant,
cDNA cloning and characterization of a new human microsomal NAD+-dependent dehydrogenase that oxidizes all-trans-retinol and 3α-hydroxysteroids
Structural analysis of the fds operon encoding the NAD+-linked formate dehydrogenase of Ralstonia eutropha
Effect of NAD+ on Malate Oxidation in Intact Plant Mitochondria
Nucleotide sequence of the Escherichia coli gap gene: Different evolutionary behavior of the NAD+‐binding domain and of the catalytic domain of D …
Oxidation of formaldehyde and acetaldehyde by NAD+-dependent dehydrogenases in rat nasal mucosal homogenates
The reaction between NAD+ and rabbit-muscle glyceraldehydephosphate dehydrogenase
Slow-binding inhibition of NAD+ glycohydrolase by arabino analogues of beta-NAD.
Macromolecular enzymatic product of NAD+ in liver mitochondria.
[112] Energy-linked reduction of NAD+ by succinate
A New Immobilized NAD+ Analogue, Its Application in Affinity Chromatography and as a Functioning Coenzyme
Dietary Niacin Deficiency Lowers Tissue Poly(ADP-Ribose) and NAD+ Concentrations in Fischer-344 Rats
Inhibition of the intrinsic NAD+ glycohydrolase activity of CD38 by carbocyclic NAD analogues
Purification and molecular characterization of the NAD+-dependent acetaldehyde/alcohol dehydrogenase from Entamoeba histolytica
THE EFFECT OF MODERATE AND MARKED HYPERCAPNIA UPON THE ENERGY STATE AND UPON THE CYTOPLASMIC NADH/NAD+ RATIO OF THE RAT …
Electrochemistry of NADH/NAD+ analogs. A detailed mechanistic kinetic and thermodynamic analysis of the 10-methylacridan/10-methylacridinium couple in …
Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 Å resolution
Structure of 3–isopropylmalate dehydrogenase in complex with NAD+: ligand–induced loop closing and mechanism for cofactor specificity
The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 Å resolution
A new NAD+-dependent opine dehydrogenase from Arthrobacter sp. strain 1C
A kinetic study of the NAD+-xylitol-dehydrogenase from the yeast Pichia stipitis
… biosensor for lactic acid based on a screen-printed carbon electrode containing Meldola’s Blue and coated with lactate dehydrogenase, NAD+ and cellulose acetate
Activities of citrate synthase, NAD+-linked and NADP+-linked isocitrate dehydrogenases, glutamate dehydrogenase, aspartate aminotransferase and alanine …
An enzyme from Saccharomyces cerevisiae uses NAD+ to transfer the splice junction 2′-phosphate from ligated tRNA to an acceptor molecule
An experimentally based family of potential energy surfaces for hydride transfer between NAD+ analogs
NAD+ levels and glucose uptake of cultured human epidermal cells exposed to sulfur mustard
Structural determination and stereospecificity of the choleragen-catalyzed reaction of NAD+ with guanidines.
Crystal structure of NH3‐dependent NAD+ synthetase from Bacillus subtilis.
2, 2′-Dichlorodiethyl sulfide (sulfur mustard) decreases NAD+ levels in human leukocytes
A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure
Enzymatic amplification for spectrophotometric and electrochemical assays of NAD+ and NADH
The binding of Ca2+ ions to pig heart NAD+-isocitrate dehydrogenase and the 2-oxoglutarate dehydrogenase complex
Molecular Cloning of the Mature NAD+-dependent Succinic Semialdehyde Dehydrogenase from Rat and Human: cDNA ISOLATION, EVOLUTIONARY …
1, 3-Propanediol: NAD+ oxidoreductases of Lactobacillus brevis and Lactobacillus buchneri
NAD+‐Dependent d‐2‐Hydroxyisocaproate Dehydrogenase of Lactobacillus Delbrueckii subsp. Bulgaricus Gene Cloning and Enzyme Characterization
A comparative study of the regulation of Ca2+ of the activities of the 2-oxoglutarate dehydrogenase complex and NAD+-isocitrate dehydrogenase from a variety of …
Nitric oxide (NO) in apoptotic versus necrotic RAW 264.7 macrophage cell death: the role of NO-donor exposure, NAD+ content, and p53 accumulation
High affinity NAD+-dependent 11β-hydroxysteroid dehydrogenase in the human heart
Mapping of the catalytic and epitopic sites of human CD38/NAD+ glycohydrolase to a functional domain in the carboxyl terminus.
Histidine 21 is at the NAD+ binding site of diphtheria toxin
Transition State Analysis of NAD+ Hydrolysis by the Cholera Toxin Catalytic Subunit
Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive …
Marcus theory of a perpendicular effect on. alpha. for hydride transfer between NAD+ analogs
Brain Levels of NADH and NAD+ Under Hypoxic and Hypoglycaemic Conditions In Vitro
NAD+ glycohydrolase, an ecto-enzyme of calf spleen cells
Electron-transfer function of NAD+-immobilized alginic acid
A novel archaebacterial NAD+‐dependent alcohol dehydrogenase: Purification and properties
Energetics of the one-electron steps in the NAD+/NADH redox couple
ADP‐Ribosylation of DNA‐Dependent RNA Polymerase of Escherichia coli by an NAD+: Protein ADP‐ribosyltransferase from Bacteriophage T4
Properties of NAD+– and NADP+-dependent malic enzymes of Rhizobium (Sinorhizobium) meliloti and differential expression of their genes in nitrogen-fixing …
A rapid NAD+-linked assay for microsomal uridine diphosphate glucuronyltransferase of rat liver and some observations on substrate specificity of the enzyme
Yeast mitochondrial NAD+-dependent isocitrate dehydrogenase is an RNA-binding protein
Structure sensitivity of the Marcus. lambda. for hydride transfer between NAD+ analogs
… expression and site-directed mutagenesis of two critical residues (tyrosine-151 and lysine-155) of human placental NAD+-dependent 15-hydroxyprostaglandin …
NAD+‐dependent internalization of the transmembrane glycoprotein CD38 in human Namalwa B cells
Crystal and molecular structure of the lithium salt of nicotinamide adenine dinucleotide dihydrate (NAD+, DPN+, cozymase, codehydrase I)
Studies on the interaction of arylazido-beta-alanyl NAD+ with the mitochondrial NADH dehydrogenase.
Thermostable NAD+-dependent alcohol dehydrogenase from Sulfolobus solfataricus: gene and protein sequence determination and relationship to other alcohol …
Slow passive diffusion of NAD+ between intact isolated plant mitochondria and suspending medium
Electrochemistry of the 9‐phenyl‐10‐methyl‐acridan/acridinium redox system; a high‐potential NADH/NAD+ analogue
Energy-linked reactions in photosynthetic bacteria: I. Succinate-linked ATP-driven NAD+ reduction by Rhodospirillum rubrum chromatophores
An efficient chemical and enzymic synthesis of nicotinamide adenine dinucleotide (NAD+)
Identification of bovine liver mitochondrial NAD+ glycohydrolase as ADP-ribosyl cyclase
The X-ray structure of Escherichia coli enoyl reductase with bound NAD+ at 2.1 Å resolution
NAD+-Linked Isocitrate Dehydrogenase: Isolation, Purification, and Characterization of the Protein from Pea Mitochondria
Metabolism of aromatic compounds in bacteria: purification and properties of the catechol-forming enzyme, 3, 5-cyclohexadiene-1, 2-diol-1-carboxylic acid (NAD+) …
Amperometric biosensors based on electrocatalytic regeneration of NAD+ at redox polymer-modified electrodes
The role of adsorption in the initial one-electron electrochemical reduction of nicotinamide adenine dinucleotide (NAD+)
Helminthosporium maydis Race T Toxin Induces Leakage of NAD+ from T Cytoplasm Corn Mitochondria
… evaluation of conformational preferences of NAD+ and NADH: an approach to understanding the stereospecificity of NAD+/NADH-dependent dehydrogenases
Nicotinamide adenine dinucleotide (NAD+). Formal potential of the NAD+/NAD· couple and NAD· dimerization rate
Development of an amperometric alcohol sensor based on immobilized alcohol dehydrogenase and entrapped NAD+
Activation of plant quinate:NAD+ 3-oxidoreductase by Ca2+ and calmodulin
Water- and solute-accessible spaces of purified peroxisomes. Evidence that peroxisomes are permeable to NAD+
Purification and structural characterization of placental NAD+-linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to …
Kinetic analysis of NAD+-isocitrate dehydrogenase with altered isocitrate binding sites: contribution of IDH1 and IDH2 subunits to regulation and catalysis
Phenylglyoxylate: NAD+ oxidoreductase (CoA benzoylating), a new enzyme of anaerobic phenylalanine metabolism in the denitrifying bacterium Azoarcus evansii
Mechanism of cyclization of pyridine nucleotides by bovine spleen NAD+ glycohydrolase
Synthesis and Kinetic Properties of a New NAD+ Derivative Carrying a Vinyl Group
Regulation of malate oxidation in plant mitochondria. Response to rotenone and exogenous NAD+
Covalent modification of proteins by metabolites of NAD+.
Redox Potentials for Yeast, Escherichia coli and Human Glutathione Reductase Relative to the NAD+/NADH Redox Couple: Enzyme Forms Active in Catalysis
The conformation of NAD+ bound to lactate dehydrogenase determined by nuclear magnetic resonance with suppression of spin diffusion
Niacin requirement and inability of tryptophan to act as a precursor of NAD+ in channel catfish, Ictalurus punctatus
Binding of NAD+ by cholera toxin
NAD+-glycohydrolase from Streptococcus pyogenes shows cyclic ADP-ribose forming activity
… with known three-dimensional structure: steady-state kinetics of the forward and reverse reactions catalysed by the NAD+-dependent glutamate dehydrogenase of …
Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome
Highly reactive and stereoselective (R)-and (S)-3-(N, N-dimethylcarbamoyl)-1, 2, 4-trimethyl-1, 4-dihydropyridines for NADH-NAD+ mimicry
… in the Dual Coenzyme-Specific Glucose-6-Phosphate Dehydrogenase fromLeuconostoc mesenteroidesThat Plays a Key Role in Binding NADP+ but Not NAD+
A few amino acid substitutions are responsible for the higher thermostability of a novel NAD+‐dependent bacillar alcohol dehydrogenase
Hydride transfer between NAD+ analogues
A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or …
Synthesis, Characterisation and Biological Significance of (2′‐5′)Oiigoadenylate Derivatives of NAD+, ADP‐Ribose and Adenosine(5′)Tetraphosph0(5′) …
Evolutionary relationship of NAD+-dependent D-lactate dehydrogenase: comparison of primary structure of 2-hydroxy acid dehydrogenases
Reusable ethanol sensor based on a NAD+-dependent dehydrogenase without coenzyme addition
Alcohol dehydrogenase (ADH) in yeasts II. NAD+‐and NADP+‐dependent alcohol dehydrogenases in Saccharomycopsis lipolytica
Enzymic electrocatalysis: electrochemical regeneration of NAD+ with immobilized lactate dehydrogenase modified electrodes
A relation between (NAD+)/(NADH) potentials and glucose utilization in rat brain slices.
3′-Deoxy-NAD+ as a substrate for poly (ADP-ribose) polymerase and the reaction mechanism of poly (ADP-ribose) elongation.
UDP-Galactose 4-Epimerase: NAD+ Content and a Charge-Transfer Band Associated with the Substrate-Induced Conformational Transition
Comparison of the effects of Ca2+, adenine nucleotides and pH on the kinetic properties of mitochondrial NAD+-isocitrate dehydrogenase and oxoglutarate dehydrogenase …
Comparison of the Kinetic Behavior toward Pyridine Nucleotides of NAD+-Linked Dehydrogenases from Plant Mitochondria
Stimulation of ADP‐Ribosyl Cyclase Activity of the Cell Surface Antigen CD38 by Zinc Ions Resulting from Inhibition of Its NAD+ Glycohydrolase Activity
Effect of pH on kinetic parameters of NAD+-dependent formate dehydrogenase
Transition State Structure of the Solvolytic Hydrolysis of NAD+
Novel Selection for Isoniazid (INH) Resistance Genes Supports a Role for NAD+-Binding Proteins in Mycobacterial INH Resistance
Metabolic Bypass of the Tricarboxylic Acid Cycle during Lipid Mobilization in Germinating Oilseeds Regulation of NAD+-Dependent Isocitrate Dehydrogenase Versus …
Isotope effects on hydride transfer between NAD+ analogs
NAD+-dependent retinol dehydrogenase in liver microsomes
Coenzyme Properties of NAD+ Bound to Different Matrices through the Amino Group in the 6‐Position
Hydride transfer and oxyanion addition equilibria of NAD+ analogs
Spectrophotometric investigation of products formed following the initial one-electron electrochemical reduction of nicotinamide adenine dinucleotide (NAD+)
Inhibition of bovine heart NAD-specific isocitrate dehydrogenase by reduced pyridine nucleotides: modulation of inhibition by ADP, NAD+, calcium (2+), citrate, and …
Role of NAD+ and ADP-Ribosylation in the Maintenance of the Golgi Structure
Chemical evidence in favor of a stabilized oxocarbonium-ion intermediate in the NAD+ glycohydrolase-catalyzed reactions
Isotope effects on binding of NAD+ to lactate dehydrogenase
Theoretical study of conformational features of NAD+ and NADH analogs: protonated nicotinamide and 1, 4-dihydronicotinamide
Transport of NAD+ in Percoll-Purified Potato Tuber Mitochondria: Inhibition of NAD+ Influx and Efflux by N-4-Azido-2-nitrophenyl-4-aminobutyryl-3′-NAD+
Photoswitching of NAD+-mediated enzyme reaction through photoreversible antigen-antibody reaction
Bacterial catabolism of threonine. Threonine degradation initiated by L-threonine-NAD+ oxidoreductase
Purification and properties of glucose-6-phosphate dehydrogenase (NADP+/NAD+) and 6-phosphogluconate dehydrogenase (NADP+/NAD+) from methanol-grown …
Electrochemical reduction of NAD+ and pyridinium cations adsorbed at the mercury/water interface: Electrochemical behavior of adsorbed pyridinyl radicals
Enzymic synthesis of NAD+ with the specific incorporation of atomic labels
Coupling of the electroenzymatic reduction of NAD+ with a synthesis reaction
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in human endometrium
X-ray study of the lithium complex of NAD+
Efficient indirect electrochemical in situ regeneration of NAD+ and NADP+ for enzymatic oxidations using iron bipyridine and phenanthroline complexes as redox …
Synthesis of Coenzymically Active Soluble and Insoluble Macromolecularized NAD+ Derivatives
NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase: detection of the mRNA in normal murine tissues and transcriptional regulation of the …
The recycling of NAD+ (free and immobilized) within semipermeable aqueous microcapsules containing a multi-enzyme system
Bi-enzyme amperometric d-lactate sensor using macromolecular NAD+
Human brain “high Km” aldehyde dehydrogenase: purification, characterization, and identification as NAD+-dependent succinic semialdehyde dehydrogenase
Molecular cloning and deduced amino acid sequences of the α- and β- subunits of mammalian NAD+-isocitrate dehydrogenase
A steady-state-kinetic model for formaldehyde dehydrogenase from human liver. A mechanism involving NAD+ and the hemimercaptal adduct of glutathione and …
Identification and partial characterization of inositol; NAD+ epimerase and inosose: NAD(P)H reductase from the fat body of the American cockroach, Periplaneta …
2′-Ribose Substituent Effects on the Chemical and Enzymic Hydrolysis of NAD+
Inhibition of cell proliferation in Saccharomyces cerevisiae by expression of human NAD+ ADP-ribosyltransferase requires the DNA binding domain (“zinc fingers”)
… relationships with quantum mechanical corrections: classical and quantum mechanical rate constants for hydride transfer between NAD+ analogs in solutions
NAD+-dependent ADP-ribosylation of T Lymphocyte Alloantigen RT6. 1 Reversibly Proceeding in Intact Rat Lymphocytes (∗)
An NAD+-dependent alanine dehydrogenase from a methylotrophic bacterium
NAD+ stimulated the spermidine-dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells
Purification and some properties of NAD+-dependent glutamate dehydrogenase from Halobacterium halobium
NAD+ analogs substituted in the purine base as substrates for poly (ADP-ribosyl) transferase
Overproduction of a 37-kilodalton cytoplasmic protein homologous to NAD+-linked d-lactate dehydrogenase associated with vancomycin resistance in …
Cyclic ADP-ribose: A calcium mobilizing metabolite of NAD+
Modulation of quinate: NAD+ oxidoreductase activity through reversible phosphorylation in carrot cell suspensions
N-Arylazido-. beta.-alanyl-NAD+, a new NAD+ photoaffinity analog. Synthesis and labeling of mitochondrial NADH dehydrogenase
Transition metal complexes of 1, 10-phenanthroline-5, 6-dione as efficient mediators for the regeneration of NAD+ in enzymatic synthesis
Molecular cloning and deduced amino acid sequences of the γ-subunits of rat and monkey NAD+-isocitrate dehydrogenases
Synthesis and properties of 2-azido-NAD+. A study of interaction with glutamate dehydrogenase.
Mechanism of action of urocanase: Specific 13C‐labelling of the prosthetic NAD+ and revision of the structure of its adduct with imidazolylpropionate
Control of mitochondrial β-oxidation: sensitivity of the trifunctional protein to [NAD+]/[NADH] and [acetyl-CoA]/[CoA]
Purification and Properties of the NAD+: Protein ADP‐ribosyltransferase Responsible for the T4‐Phage‐Induced Modification of the œ Subunit of DNA‐Dependent RNA …
Simultaneous extraction and combined bioluminescent assay of NAD+ and NADH
Lung poly (ADP-ribose) and NAD+ concentrations during hyperoxia and niacin deficiency in the Fischer-344 rat
Effect of age and gender on in vivo ethanol elimination, hepatic alcohol dehydrogenase activity, and NAD+ availability in F344 rats
Theoretical Investigation of the Hydride Transfer from Formate to NAD+ and the Implications for the Catalytic Mechanism of Formate Dehydrogenase
Cytosolic NAD+ content strictly depends on ATP concentration in isolated liver cells
Plant mitochondrial NAD+-dependent malic enzyme. cDNA cloning, deduced primary structure of the 59-and 62-kDa subunits, import, gene complexity and …
Crystallization of an NAD+-dependent glutamate dehydrogenase from Clostridium symbiosum
Pyridine coenzyme analogs. 3. Synthesis of three NAD+ analogs containing a 2′-deoxy-2′-substituted nicotinamide arabinofuranosyl moiety
Interactions and spatial arrangement of spin-labeled NAD+ bound to glyceraldehyde-3-phosphate dehydrogenase. Comparison of EPR and X-ray modeling data.
Human Nuclear NAD+ ADP-Ribosyltransferase(polymerizing): Organization of the Gene
Characterization of a cDNA clone for human NAD+-specific isocitrate dehydrogenase α-subunit and structural comparison with its isoenzymes from different species
REGENERATION OF NAD+ AND NADP+ COFACTORS BY PHOTOSENSITIZED ELECTRON TRANSFER
The rhodium complex of a tris(bipyridine) ligand—Its electrochemical behaviour and function as mediator for the regeneration of NADH from NAD+
Measured and calculated NAD+/NADH ratios in human erythrocytes
Isolation and characterization of a novel eukaryotic monofunctional NAD+-dependent 5, 10-methylenetetrahydrofolate dehydrogenase
Sulfoxylate ion (HSO2-), the hydride donor in dithionite-dependent reduction of NAD+ analogs
Cloning of the Staphylococcus aureus ddh gene encoding NAD+-dependent d-lactate dehydrogenase and insertional inactivation in a glycopeptide-resistant isolate
A reagentless amperometric electrode based on carbon paste, chemically modified with D‐lactate dehydrogenase, NAD+, and mediator containing polymer for D …
Human nuclear NAD+ ADP-ribosyltransferase: localization of the gene on chromosome 1q41-q42 and expression of an active human enzyme in Escherichia coli.
Transglutaminase-catalysed Formation of Coenzymatically Active NAD+ Analog • Casein Conjugates
NAD+-malic enzyme. Regulatory properties of the enzyme from Ascaris suum.
Affinity purification and kinetic analysis of mutant forms of yeast NAD+-specific isocitrate dehydrogenase
8‐Azidoadenine Analogs of NAD+ and FAD: Synthesis and Coenzyme Properties with NAD+ ‐Dependent and FAD‐Dependent Enzymes
Biomimetic Oxidation of Aldehyde with NAD+ Models: Glycolysis‐Type Hydrogen Transfer in an NAD+/NADH Model System
Production of essential L‐branched‐chain amino acids in bioreactors containing artificial cells immobilized multienzyme systems and dextran–NAD+
Fluorescence in situ mapping of the human nuclear NAD+ ADP-ribosyltransferase gene (ADPRT) and two secondary sites to human chromosomal bands 1q42, 13q34 …
Pyruvate catabolism during transient state conditions in chemostat cultures of Enterococcus faecalis NCTC 775: importance of internal pyruvate concentrations and NADH/NAD …
Structural properties of long- and short-chain alcohol dehydrogenases. Contribution of NAD+ to stability
Rat RT6. 2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity.
Dynamics of hydride transfer between NAD+ analogs
Kinetics of the catalysis by the Alcaligenes eutrophus H16 hydrogenase of the electrochemical reduction of NAD+
ATPase activity of isolated plasma membrane vesicles of leaves of Elodea as affected by thiol reagents and NADH/NAD+ ratio
Submitochondrial localization of the NAD+ glycohydrolase. Implications for the role of pyridine nucleotide hydrolysis in mitochondrial calcium fluxes.
Classical Raman spectroscopic studies of NADH and NAD+ bound to lactate dehydrogenase by difference techniques
2-Azido-[32P] NAD+, a photoactivatable probe for G-protein structure: evidence for holotransducin oligomers in which the ADP-ribosylated carboxyl terminus of alpha …
Regulation of NAD+ glycohydrolase activity by NAD+-dependent auto-ADP-ribosylation
Histochemical studies of Ca-ATPase, succinate and NAD+-dependent isocitrate dehydrogenases in the shell gland of laying Japanese quails: with special reference …
Classical Raman spectroscopic studies of NADH and NAD+ bound to liver alcohol dehydrogenase by difference techniques
Histidine-21 is involved in diphtheria toxin NAD+ binding
The effect of raising the NAD+ content on the pathways of carbohydrate metabolism and lipogenesis in rat liver.
Three-dimensional model of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase and relationships to the NADP+-dependent enzyme (carbonyl reductase)
Candida utilis NAD+ kinase: purification, properties and affinity gel studies.
Use of pyridinium and flavin derivatives for recycling of catalystic amounts of NAD+ during preparative-scale horse liver alchohol dehydrogenase-catalysed oxidations …
Purification and properties of a mitochondrial NAD+ glycohydrolase
Bimolecular reactions of pyridinyl radicals in water and the mechanism of NAD+-NADH dehydrogenase reactions
Molecular characterization and expression of the gene for mouse NAD+: arginine ecto-mono (ADP-ribosyl) transferase, Art1
Molecular characterization of a novel, nuclear-encoded, NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase in plastids of the gymnosperm Pinus …
Circulating IgG-LD complex, dissociable by addition of NAD+.
12-L-hydroxy-5, 8, 10-heptadecatrienoic acid (HHT) is an excellent substrate for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Regulation of energy metabolism in Trypanosoma (schizotrypanum) cruzi epimastigotes. II. NAD+-dependent ǵlutamate dehydrogenase
Purification, properties, and metabolic roles of NAD+-glutamate dehydrogenase in Clostridium botulinum 113B
A novel type of pyridine nucleotide-disulfide oxidoreductase is essential for NAD+-and NADPH-dependent degradation of epoxyalkanes by Xanthobacter strain Py2
Purification and Properties of Glycerol: NAD+ 2-Oxidoreductase (Glycerol Dehydrogenase) from Schizosaccharomyces pombe
The binding of tyrosine and NAD+ to chorismate mutase/prephenate dehydrogenase from Escherichia coli K12 and the effects of these ligands on the activity and self …
Actions of NAD+ on renal brush border transport of phosphate in vivo and in vitro
A conformational transition of the oligomer of glutamate dehydrogenase induced by half-saturation with NAD+ or NADP+
A lactate dehydrogenase amperometric pyruvate electrode exploiting direct detection of NAD+ at a poly (3-methylthiophene): Poly (phenol red) modified platinum …
Redox potentials and acid-base equilibria of NADH/NAD+ analogs in acetonitrile
Thiosulfate-linked ATP-dependent NAD+ reduction in Rhodopseudomonas palustris
Purification and Characterization of a NAD+-Dependent Formate Dehydrogenase Produced by Paracoccus sp.
Involvement of cytosolic NAD+ glycohydrolase in cyclic ADP-ribose metabolism
Enantioselective dehydrogenation of β-hydroxysilanes by horse liver alcohol dehydrogenase with a novel in-situ NAD+ regeneration system
Cloning and overexpression of the Lactobacillus bulgaricus NAD+-dependent D-lactate dehydrogenase gene in Escherichia coli: purification and characterization of …
Regulation of bile acid 7-dehydroxylase activity by NAD+ and NADH in cell extracts of Eubacterium species VPI 12708
Bioelectrocatalysis of NAD+ reduction
Demonstration and possible function of NADH: NAD+ transhydrogenase from ascaris muscle mitochondria.
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney: I. Purification and partial characterization
The effect of alcohol stress on nicotinamide adenine dinucleotide (NAD+) levels in Drosophila
… role of the pentose phosphate shunt in glucose-induced insulin release: in vitro studies with 6-aminonicotinamide, methylene blue, NAD+, NADH, NADP+, NADPH …
… –NAD+ transhydrogenase peptide of the mitochondrial NADH-CoQ reductase (Complex I). A photodependent labeling study utilizing arylazido-beta-alanyl NAD+.
Transient Kinetics of Intracomplex Electron-Transfer in the Human Cytochrome B5 Reductase-Cytochrome B5 System: NAD+ Modulates Protein-Protein Binding and …
Cloning and expression of the cDNA for mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
… polyethyleneimine microcapsules for immobilizing multienzymes with soluble dextran-NAD+ for the continuous recycling of the microencapsulated dextran-NAD+
Characterization of the genomic structure and promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene
Application of linear free-energy relationships to the mechanistic probing of nonenzymatic and NAD+-glycohydrolase-catalyzed hydrolysis of pyridine dinucleotides
Conformation of NAD+ bound to yeast and horse liver alcohol dehydrogenase in solution: The use of the proton-proton transferred nuclear Overhauser enhancement
Inhibition of NAD+ glycohydrolase and ADP-ribosyl cyclase activities of leukocyte cell surface antigen CD38 by gangliosides
Mechanistic study of the addition of pyruvate to NAD+ catalyzed by lactate dehydrogenase
Purification and characterization of NAD+:ADP-ribosyltransferase (polymerizing) from Dictyostelium discoideum
On the mechanism of action of calf spleen NAD+ glycohydrolase
Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD + ADP ribosyl transferase in rats
Site-directed mutagenesis of the conserved serine 138 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase to an alanine results in an …
The binding of NAD+ to rabbit muscle glyceraldehyde-3-phosphate dehydrogenase studied by protein fluorescence quenching
Regeneration of NAD+ cofactor by photosensitized electron transfer in an immobilized alcohol dehydrogenase system
Structure of the liver alcohol dehydrogenase-NAD+-pyrazole complex as determined by nitrogen-15 NMR spectroscopy
Photolabelling of mutant forms of the S1 subunit of pertussis toxin with NAD+
Immunochemical properties of NAD+-linked glycerol dehydrogenases from Escherichia coli and Klebsiella pneumoniae
Coenzymatic properties of low molecular-weight and macromolecular N6-derivatives of NAD+ and NADP+ with dehydrogenases of interest for organic synthesis
Chloranil as a Catalyst for the Electrochemical Oxidation of NADH to NAD+
Crystallization of Arthrobacter sp. strain 1C N-(1-D-carboxyethyl)-L-norvaline dehydrogenase and its complex with NAD+
New Coenzymically‐Active Soluble and Insoluble Macromolecular NAD + Derivatives
Allosteric effect of fructose 1, 6-bisphosphate on the conformation of NAD+ as bound to L-lactate dehydrogenase from Thermus caldophilus GK24.
Bioelectrocatalytic reduction of NAD+ to NADH on diaphorase modified electrodes
Preparation and properties of rabbit-muscle glyceraldehyde-phosphate dehydrogenase with equal binding parameters for the third and fourth NAD+ molecules.
… analysis of eletrochemical reactions involving two successive one-electron transfers with dimerization of intermediate-applicaiton to NAD+/NADH redox couple
The Activation of Ox‐Brain NAD+‐Dependent Isocitrate Dehydrogenase by Magnesium Ions
Abnormal NAD+ levels in cells from patients with Fanconi’s anaemia
Conformational Studies on Lipoamide Dehydrogenase from Pig Heart: 4. The Binding of NAD+ to Non‐Equivalent Sites
Marcus theory of hydride transfer from an anionic reduced deazaflavin to NAD+ analogs
Photochemical labeling of yeast alcohol dehydrogenase with an azide analog of NAD+
Micro method for determination of borohydride with NAD+
Mechanistic implications of cyclic ADP-ribose hydrolysis and methanolysis catalyzed by calf spleen NAD+ glycohydrolase
Inactivation of S-adenosyl-L-homocysteine hydrolase by cAMP results from dissociation of enzyme-bound NAD+.
Sensitivity to pH, product inhibition, and inhibition by NAD+ of 1, 3-propanediol dehydrogenase purified from Enterobacter agglomerans CNCM 1210
Cloning of cDNA encoding an NAD+-dependent isoform of 11β-hydroxysteroid dehydrogenase in sheep kidney
Involvement of a single thiol group in the conversion of the NAD+-dependent activity of rat liver xanthine oxidoreductase to the O2-dependent activity
The role of NAD+ as a signal during nitrogenase switch-off in Rhodospirillum rubrum
The Metabolism of [carboxyl-14C]Anthranilic Acid: I. The Incorporation of Radioactivity into NAD+ and NADP+
Oxygen free radicals enhance the nitric oxide-induced covalent NAD+-linkage to neuronal glyceraldehyde-3-phosphate dehydrogenase
Stimulation of synthesis de novo of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester
Analysis of the promoter of the NAD+ dependent 11β-hydroxysteroid dehydrogenase (HSD11K) gene in JEG-3 human choriocarcinoma cells
The synthesis of spin-label derivatives of NAD+ and its structural components and their binding to lactate dehydrogenase
The effect of substrates, effectors, acetyl phosphate and iodoacetate on the binding of NAD+ and NADH to rabbit-muscle glyceraldehydephosphate dehydrogenase
Hydrolysis of nicotinamide-adenine dinucleotide by purified renal brush-border membranes. Mechanism of NAD+ inhibition of brush-border membrane phosphate …
Conformation of NAD+ bound to allosteric L-lactate dehydrogenase activated by chemical modification
Electrochemical regeneration of NAD+. A new evaluation of its actual yield
Effects of γ Radiation and Hyperthermia on DNA Repair Synthesis and the Level of NAD+ in Cultured Human Mononuclear Leukocytes
The effect of NAD+ on the catalytic efficiency of glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle
Direct electrochemistry of the flavin domain of assimilatory nitrate reductase: effects of NAD+ and NAD+ analogs
Regulation of synthesis and activity of NAD+-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human …
Identification and purification of a bovine liver mitochondrial NAD+-glycohydrolase
Activation of calmodulin-dependent NAD+ kinase by trypsin
The MTCY428.08 Gene ofMycobacterium tuberculosis Codes for NAD+ Synthetase
Efficient NAD+-regeneration system with heteroaromatic o-quinones and molecular oxygen
NAD+ binding site of Clostridium botulinum C3 ADP-ribosyltransferase. Identification of peptide in the adenine ring binding domain using 2-azido NAD.
Construction of a new leucine dehydrogenase with preferred specificity for NADP+ by site-directed mutagenesis of the strictly NAD+-specific enzyme.
Bienzyne Electrodes for ATP, NAD+, Starch and Disaccharides Based on a Glucose Sensor
Genetics of ocular NAD+-dependent alcohol dehydrogenase and aldehyde dehydrogenase in the mouse: Evidence for genetic identity with stomach isozymes and localization …
UMP-dependent reduction of UDP-galactose 4-epimerase-NAD+ complex by sodium cyanoborohydride
A role for NAD+ and cADP-ribose in melatonin signal transduction
Purification and characterization of a NAD+-dependent secondary alcohol dehydrogenase from propane-grown Rhodococcus rhodochrous PNKb1
Activity of NMN+, nicotinamide ribose and analogs in alcohol oxidation promoted by horse‐liver alcohol dehydrogenase: Improvement of this activity and structural requirements …
Isolation, characterization, and biological activity of ferredoxin-NAD+ reductase from the methane oxidizer Methylosinus trichosporium OB3b
Immobilization of alcohol dehydrogenase, malic dehydrogenase and dextran—NAD+ within nylon-polyethyleneimine microcapsules: preparation and cofactor …
Mitochondrial membrane potential, transmembrane difference in the NAD+ redox potential and the equilibrium of the glutamate-aspartate translocase in the isolated …
Characterization and expression of the plasmid-borne bedD gene from Pseudomonas putida ML2, which codes for a NAD+-dependent cis-benzene dihydrodiol …
Mechanisms of reductive methylation of NAD+ analogues by a trans-dimethylcobalt (III) complex
Calf spleen NAD+ glycohydrolase: solubilization, purification, and properties of the intact form of the enzyme
UDP-galactose 4-epimerase. Phosphorus-31 nuclear magnetic resonance analysis of NAD+ and NADH bound at the active site
Membrane-associated NAD+ glycohydrolase from rabbit erythrocytes is solubilized by phosphatidylinositol-specific phospholipase C
Electrolytic regeneration of NADH from NAD+ with a liquid crystal membrane electrode
Poly (ADP-ribose) biosynthesis and suicidal NAD+ depletion following carcinogen exposure of mammalian cells
Control of fatty acid oxidation by intramitochondrial [NADH]/[NAD+] in developing rat small intestine
The redox state of NAD+-NADH systems in rat liver during ketosis, and the so-called “triosephosphate block”
Evidence for the presence of a new NAD+-dependent formate dehydrogenase in Pseudomonas sp. 101 cells grown on a molybdenum-containing medium
Reduction of NAD+ and NADP+ and reductive cleavage of NADH and NADPH yielding NAD. and NADP.
Selective enzyme amplification of NAD+/NADH using coimmobilized glycerol dehydrogenase and diaphorase with amperometric detection
Association of the quinate : NAD+ oxidoreductase with one dehydroquinate hydro-lyase isoenzyme in corn seedlings
An NAD+-independent L-lactate dehydrogenase from Rhizopus oryzae
Direct electrochemistry of Rhodococcus opacus hydrogenase for the catalysis of NAD+ reduction
The calculation of the mitochondrial free [NAD+]/[NADH][H+] ratio in brain: effect of electroconvulsive seizure
Substrate and metal ion interactions in the NAD+ malic enzyme from cauliflower
Regioselectivity of hydride transfer to and between NAD+ analogs
Surface-enhanced Raman spectroscopy of NAD+ and related compounds
Transition metal requirement to express high level NAD+-dependent formate dehydrogenase from a serine-type methylotrophic bacterium
Conformational changes of glyceraldehyde-3-phosphate dehydrogenase induced by the binding of NAD+: A unified model for positive and negative cooperativity
Rapid purification of pig heart NAD+-isocitrate dehydrogenase. Studies on the regulation of activity by Ca2+, adenine nucleotides, Mg2+ and other metal ions
Enzyme Electrode for Amplification of NAD+/NADH Using Glycerol Dehydrogenase and Diaphorase with Amperometric Detection
Bovine heart mitochondrial transhydrogenase catalyzes an exchange reaction between NADH and NAD+.
Glucose oxidase bienzyme electrodes for ATP, NAD+, starch and disaccharides
Isolation and characterization of a Chinese hamster ovary cell line deficient in fatty alcohol: NAD+ oxidoreductase activity.
Synthesis of carbocyclic NAD+ containing a methylenebisphosphonate linkage for the investigation of ADP-ribosyl cyclase
DNA repair dependent NAD+ metabolism is impaired in cells from patients with Fanconi’s anemia.
The Effect of pH on the Allosteric Behaviour of Ox‐Brain NAD+‐Dependent Isocitrate Dehydrogenase
Purification and characterization of glycerol-3-phosphate dehydrogenase (NAD+) in the salt-tolerant yeast Debaryomyces hansenii
Topography, purification and characterization of thyroidal NAD+ glycohydrolase
FAD-mediated enzymatic conversion of NAD+ to NADH: application to chiral synthesis of L-lactate
Effects of Hyperthermia and Nicotinamide on DNA Repair Synthesis, ADP-ribosyl Transferase Activity, NAD+ and ATP Pools, and Cytotoxicity in γ-irradiated Human …
Stereoselective hydride uptake in modelsystems related to the redox-couple NAD+/nadh
Bilirubin: a potent inhibitor of NAD+-linked isocitrate dehydrogenase
Ichthyosis, mental retardation, and asymptomatic spasticity: a new neurocutaneous syndrome with normal fatty alcohol: NAD+ oxidoreductase activity
Do organophosphate insecticides inhibit the conversion of tryptophan to NAD+ in ovo?
Effects of NAD+ Binding on the Luminescence of Tryptophans 84 and 310 of Glyceraldehyde-3-phosphate Dehydrogenase from Bacillus stearothermophilus
Distribution of prostaglandin E 9-ketoreductase and NAD+-dependent and NADP+-dependent 15-hydroxyprostaglandin dehydrogenase in the renal cortex and …
Kinetics and Dissociation Constants of Liver Alcohol Dehydrogenase with 3‐Acetyl Pyridine NAD+ and NADH
Gene structure, expression in Escherichia coli and biochemical properties of the NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase from Pinus sylvestris …
… essential amino acids, L‐leucine, L‐valine, and L‐isoleucine, using artificial cells containing an immobilized multienzyme system and dextran‐NAD+. 2. Yeast alcohol …
Preparation of 3-chloroacetylpyridine adenine dinucleotide: An alkylating analogue of NAD+
NAD+-specific glycerol 3-phosphate dehydrogenase from developing castor bean endosperm
Electrostatic effects of bound NADH and NAD+ on ionizing groups in liver alcohol dehydrogenase
A new highly selective physicochemical assay to measure NAD+ in intact cells
Characterization of Detergent-Solubilized Beef Liver Mitochondrial NAD+ Glycohydrolase and Its Truncated Hydrosoluble Form
Effect of NADH on hypoxanthine hydroxylation by native NAD+-dependent xanthine oxidoreductase of rat liver, and the possible biological role of this effect
Monoclonal antibodies that inhibit the enzyme activity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Patterns of Product Inhibition of a Bifunctional Dehydrogenase; l‐Histidinol : NAD+ Oxidoreductase
Effects of calcium ions and adenosine diphosphate on the activities of NAD+-linked isocitrate dehydrogenase from the radular muscles of the whelk and flight muscles …
Nuclear magnetic resonance studies on pyridine dinucleotides: The pH dependence of the carbon-13 nuclear magnetic resonance of NAD+ analogs
Localization and properties of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in the rat kidney
Identification of an NAD+ binding site of brain glutamate dehydrogenase isoproteins by photoaffinity labeling
Exogenous NAD+ Effects on Plant Mitochondria: A Reinvestigation of the Transhydrogenase Hypothesis
Spatial arrangement of coenzyme and substrates bound to L-3-hydroxyacyl-CoA dehydrogenase as studied by spin-labeled analogs of NAD+ and CoA
Electrochemical characterization of immobilized NAD+
Comparative adsorption of adenine and nicotinamide adenine dinucleotide (NAD+) at an aqueous solution/mercury interface
NAD+ kinase activity in root tips of nearly Isogenic linesof wheat (Triticum aestivum L.) that differ in their tolerance to aluminium
Enzymatic Improvement of Food Flavor. V. Oxidation of Aldehydes in Soybean Extracts by an NAD+-Regenerating System Made up of Aldehyde …
Induction by retinoic acid of NAD+-glycohydrolase activity of myelomonocytic cell lines HL-60, THP-1 and U-937, and fresh human acute promyelocytic leukemia cells …
Ester Synthesis by NAD+-dependent Dehydrogenation of Hemiacetal: Production of Methyl Formate by Cells of Methylotrophic Yeasts
Conformational Variability of NAD+ in the Free and Bound States: a Nicotinamide Sandwich in NAD+ Crystals
Characterization of metastable intermediates of enzymatic peroxidation of NAD+ by on‐line capillary electrophoresis/electrospray ionization mass spectrometry
The effect of NAD+ and NAD+ analogs on protein synthesis in rabbit reticulocytes: Replacement of the energy regenerating system
Ca2+ dependence of gluconeogenesis stimulation by glucagon at different cytosolic NAD+-NADH redox potentials
Alternative NAD+-dependent formate dehydrogenases in the facultative methylotroph Mycobacterium vaccae 10
NAD+/NADH recycling by coimmobilized lactate dehydrogenase and glutamate dehydrogenase
Electrochemical behaviour of 1-benzyl-3-carbamoylpyridinium chloride, a NAD+ model compound
Isolation and properties of glyceraldehyde-3-phosphate dehydrogenase from a sturgeon from the Caspian Sea and its interaction with spin-labeled NAD+ derivatives
Submitochondrial Location and Some Properties of NAD+ – and NADP+-Linked Malate Dehydrogenase in Euglena
Purification of lipoamide dehydrogenase from Ascaris muscle mitochondria and its relationship to NADH: NAD+ transhydrogenase activity
Cloning and expression of the cDNA for rat NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
IFCC methods for the measurement of catalytic concentration of enzymes. Part 8. IFCC method for lactate dehydrogenase (L-lactate: NAD+ oxidoreductase, EC 1.1 …
Binding of NAD+ to pertussis toxin.
The purification of a cysteine-dependent NAD+ glycohydrolase activity from bovine erythrocytes and evidence that it exhibits a novel ADP-ribosyltransferase activity
Molecular characterization of glycosomal NAD+-dependent glycerol 3-phosphate dehydrogenase from Trypanosoma brucei rhodesiense
Effects of cold on NAD+ kinase activity in winter rape plants
NAD+ biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet
Preparation and kinetic properties of 5‐ethylphenazine – poly(ethylene glycol) – NAD+ conjugate, a unique catalyst having an intramolecular reaction step
Determination of the concentration of free Ca2+ in the presence of magnesium (or manganese) and chelating effectors of the NAD+-linked isocitrate dehydrogenase
NAD+-dependent oxidation of 20-hydroxyleukotriene B4 to 20-carboxyleukotriene B4 by rat liver cytosol
Mutations in theIDH2Gene Encoding the Catalytic Subunit of the Yeast NAD+-Dependent Isocitrate Dehydrogenase Can Be Suppressed by Mutations in theCIT1Gene …
Potentiation of alkylation-induced sister chromatid exchange frequency by 3-aminobenzamide is mediated by intracellular loss of NAD +
Subunit interactions in rabbit-muscle glyceraldehyde-phosphate dehydrogenase, as measured by NAD+ and NADH binding.
Identification of an (arylazido)-. beta.-alanyl-NAD+-modified site in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase by microsequencing and fast atom …
Evidence of a role for NAD+-glycohydrolase and ADP-ribosyltransferase in growth and differentiation of Streptomyces griseus NRRL B-2682: inhibition by m …
The electrochemical regeneration of NAD+ revisited
Anaerobic energy metabolism of goldfish,Carassius auratus (L.) Effects of anoxia on the measured and calculated NAD+/NADH ratios in muscle and liver
NAD+-glycohydrolase productivity of haemolytic streptococci assayed by a simple fluorescent method and its relation to T serotype
Catalytic activity of noncovalent complexes of horse liver alcohol dehydrogenase, NAD+ and polymers, dissolved or suspended in organic solvents
NAD+-dependent ADP-ribosyltransferase in renal brush-border membranes
Isozymes of Glucose-6-phosphate Dehydrogenase and NAD+-malate Dehydrogenase in Shoot-forming Foliar Discs of Tobacco
An enzymatic cycling procedure for NAD+ using an irreversible reaction with NAD+-peroxidase
Identification of peptides in the adenine ring binding domain of glutamate and lactate dehydrogenase using 2-azido-NAD+
The nature of the substrate inhibition in lactate dehydrogenases as studied by a spin-labeled derivative of NAD+
ELECTROCONVULSIVE SEIZURE: AN INVESTIGATION INTO THE VALIDITY OF CALCULATING THE CYTOPLASMIC FREE [NAD+]/[NADH] [H+] RATIO FROM …
Characterization of the NAD+ Glycohydrolase Associated with the Rat Liver Nuclear Envelope
One-electron Reduction of 1-Benzyl-3-carbamoylpyridinium as a NAD+ Model
NAD+ biosynthesis from tryptophan in the presence of nicotinic acid or vice versa by rat hepatocytes–effect of clofibrate-feeding.
Modification of alcohol dehydrogenases with two NAD+-analogues containing reactive substituents on the functional side of the molecule
NAD+-induced inhibition of phosphate transport in canine renal brush-border membranes Mediation through a process other than or in addition to NAD+ hydrolysis
Drosophila melanogaster alcohol dehydrogenase. Biochemical properties of the NAD+-plus-acetone-induced isoenzyme conversion
Inhibition of cADPR-hydrolase by ADP-ribose potentiates cADPR synthesis from β-NAD+
The synthesis of N 6‐(6‐aminohexyl)‐NAD+ and its application to affinity chromatography
Stimulation and inhibition of the protein synthetic process by NAD+ in lysed rabbit reticulocytes.
The effect of adenine nucleotides and dehydroepiandrosterone on the isoenzymes of NADP+-and NAD+-glucose-6-phosphate dehydrogenase and 6 …
Study of Coenzyme Binding Site of Octopine Dehydrogenase Using Analogues of NAD+
Calatytic Mechanism and Activity of Bis(2,2′ : 6′,2″-terpyridine) rhodium(III) for the Reduction of NAD+ into NADH in a Photosensitized Reaction System
Provoked changes in cellular calcium controlled protein phosphorylation and activity of quinate: NAD+ oxidoreductase in carrot cells
NAD+ Dependent Alcohol Dehydrogenase from Sulfolobus Solfataricus: Structural and Functional Features
Cysteine 182 is essential for enzymatic activity of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Electrochemical bioreactor with regeneration of NAD+ by rotating graphite disk electrode with PMS adsorbed
D-1-amino-2-propanol: NAD+ oxidoreductase. Purification and general properties of the large molecular form of the enzyme from Escherichia coli K12.
The use of bacterial luciferase and a liquid scintillation spectrometer to assay the enzymatic synthesis of NAD+
Developmental regulation of NAD+ kinase in Neurospora crassa
Entrapment of co-enzymically active NAD+ polymers in fibres
Effect of monovalent cations on the inhibition by NAD+ of NADH oxidation in submitochondrial particles
Partial purification and characteristics of membrane-associated NAD+-dependent isocitrate dehydrogenase activity from etiolated pea mitochondria
NAD+-dependent conversion of 20-OH-LTB4 to 20-COOH-LTB4 by a cell-free system of human polymorphonuclear leukocytes
Nitric Oxide–Induced Modification of Glyceraldehyde-3-Phosphate Dehydrogenase with NAD+ Is Not ADP-Ribosylation
Photoinduced Hydride Reduction of an NAD+ Analogue with Permethylpolysilanes Acting as Electron Sources and Water as a Proton Source
Modulation of Ca2+-dependent K+ transport by modifications of the NAD+/NADH ratio in intact human red cells
Kinetic and modelling studies of NAD+ and poly (ethylene glycol)-bound NAD+ in horse liver alcohol dehydrogenase
Effects of univalent cations on the properties of yeast NAD+ acetaldehyde dehydrogenase
Conversion of α‐ketoglutarate into L‐glutamic acid with urea as ammonium source using multienzyme systems and dextran‐NAD+ immobilized by …
Inactivation of pulmonary NAD+-dependent 15-hydroxyprostaglandin dehydrogenase by acrolein
Isolation of a cDNA clone for human NAD+: protein ADP-ribosyltransferase.
Effect of increasing the intracellular ratio of NADH to NAD+ on human erythrocyte metabolism: new estimation of the turnover through the phosphoglycerate shunt
… or urea into L-leucine, L-valine, and L-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD+. Glucose dehydrogenase for …
Evidence for an Essential Lysine at the Active Site of l‐Histidinol : NAD+ Oxidoreductase; a Bifunctional Dehydrogenase
Alkylation of Adenine, Adenosine, and NAD+ with 1,3‐Propanesultone. Synthesis of N6‐(3‐sulfonatopropyl)‐NAD+, a new NAD+ derivative with substantial …
A calcium-binding protein is a regulatory subunit of quinate: NAD+ oxidoreductase from dark-grown carrot cells
Poly (ADP-ribose) polymerase inhibits DNA synthesis initiation in the absence of NAD+
Preparations of holodehydrogenases by covalent fixation of NAD+-analogs to alcohol and lactate dehydrogenase
Uridine diphosphate galactose 4-epimerase. pH dependence of the reduction of NAD+ by a substrate analog.
Characterization and reconstitution of a cell free system for NAD+-dependent deoxyhypusine formation on the 18 kDa eIF-4D precursor
Electrochemical reduction of ε-adenine, ε-adenosine, and ε-NAD+ in aqueous media
Transmural gradient of NAD+/NADH ratio in the canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient
Further studies on the bioaffinity chromatography of NAD+-dependent dehydrogenases using the locking-on effect
Alcohol: NAD+ Oxidoreductase Is Present in Rat Liver Peroxisomes (∗)
Novel photocatalytic NAD+ recycling system with a semiconductor in organic solvent
Skeletal muscle NAD+ (P) and NADP+‐dependent malic enzyme in Friedreich’s ataxia
NAD+ and NAD+ analogues in horse liver alcohol dehydrogenase. Relationship between reactivity and conformation simulated with molecular mechanics
A Two‐step Synthesis of New Water‐Soluble Polymers of NAD+ and ADP: The Biological Properties of These Polymers
NAD+ and NADH regulate an ATP-dependent kinase that phosphorylates enzyme I of the Escherichia coli phosphotransferase system.
NAD+-mediated stimulation of adenylate cyclase in cardiac membranes
A study of formaldehyde dismutation by liver alcohol dehydrogenase with NAD+-analogs
… peptide labeled by 2-(4-bromo-2, 3-dioxobutylthio) adenosine 5′-diphosphate in the allosteric ADP site of pig heart NAD+-dependent isocitrate dehydrogenase
Pressure relaxation studies of isomerisations of horse liver alcohol dehydrogenase linked to NAD+ binding
Simplified luciferase assay of NAD+ applied to microsamples from liver, kidney and pancreatic islets
Redox Polymer-Modified Electrodes for the Electrocatalytic Regeneration of NAD+
Assimilatory nitrate reductase: reduction and inhibition by NADH/NAD+ analogs
Purification of malic enzyme from Ascaris suum using NAD+-agarose
L-fucose metabolism in mammals. Kinetic studies on pork liver 2-keto-3-deoxy-L-fuconate: NAD+ oxidoreductase
Purification and characterization of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney
Red-ox transformations of NAD+ model compounds
Role of NAD+ in the stimulation of protein synthesis in rabbit reticulocyte lysates
The amino acid composition and some properties of the NAD+-specific glutamate dehydrogenase from Neurospora crassa
Sequence of a novel mRNA coding for a C-terminal-truncated form of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
A comparative study of NAD+ binding sites in dehydrogenases by circular polarization of fluorescence
The presence of α-glycerophosphate dehydrogenase (NAD+-linked) and adenylate kinase as core and integral membrane enzymes respectively in the glycosomes of …
Reaction of 4-trans-(N, N-dimethylamino) cinnamaldehyde with the liver alcohol dehydrogenase-NAD+ complex
… of Escherichia coli D-1-amino-2-propanol: NAD+ oxidoreductase with E. coli glycerol dehydrogenase but not with Neisseria gonorrhoeae 1, 2-propanediol: NAD+ …
Crystallization and quaternary structure analysis of the NAD+-dependent leucine dehydrogenase from Bacillus sphaericus
Isolation and Some Properties of NAD+ Reductase of the Green Photosynthetic Bacterium Prosthecochloris aestuarii
Targeting of liposomes by covalent coupling with ecto-NAD+-glycohydrolase ligands
Effect of nicotinamide-adenine dinucleotides on Ca2+ transport system in rat liver nuclei: stimulation of Ca2+ release by NAD+
6-Phospho-D-gluconate: NAD+ 2-oxidoreductase (decarboxylating) from slow-growing rhizobia
A simple, rapid extraction and assay procedure for NAD+-dependent sorbitol dehydrogenase (SDH) in peach
Covalent binding of an NAD+ analogue to horse liver alcohol dehydrogenase in a ternary complex with pyrazole
Structure-function studies on glyceraldehyde-3-phosphate dehydrogenase. III. Dependency of proteolysis on NAD+ concentration
Chiral discrimination in the quenching of an enzyme-bound fluorescent NAD+ analog by an optically active quencher
The redox state of NAD+/NADH systems in guinea pig liver during increased fatty acid oxidation
S-adenosyl-L-homocysteine hydrolase from Dictyostelium discoideum is inactivated by cAMP and reactivated by NAD+
Catalytic mechanism and interactions of NAD+ with glyceraldehyde-3-phosphate dehydrogenase: correlation of EPR data and enzymatic studies
Preparation and Properties of 3‐Halopyridine–adenine Dinucleotides, NAD + Analogues and of Model Compounds
Conformations of the coenzymes and the allosteric activator, ADP, bound to NAD+-dependent isocitrate dehydrogenase from pig heart
Light-induced conversion of NAD+ to NADP+ in Chlorella cells
Oxidative Phosphorylation in Micrococcus denitrfricans III. ATP-supported Reduction of NAD+ by Succinate
Generation of Reactive Oxygen Species and Reduction of Ferric Chelates by Microsomes in the Presence of a Reconstituted System Containing Ethanol, NAD+ and …
Syntheses and redox behavior of novel cyclic hosts having multiple redox centers of NAD+ analogue
Recycling of NAD+ using coimmobilized alcohol dehydrogenase andE. coli
Molecular mechanics calculation of geometries of NAD+ derivatives, modified in the nicotinamide group, in a ternary complex with horse liver alcohol dehydrogenase
Synthesis and properties of (4‐13C)NAD+ Observation of its binding to yeast alcohol dehydrogenase by 13C‐NMR spectroscopy
NAD+-dependent isocitrate dehydrogenase from Arabidopsis thaliana. Characterization of two closely related subunits
NAD+-Glycohydrolase of Thyroid Homogenates
Purification and Characterization of a New NAD+-Dependent Enzyme, L-Tartrate Decarboxylase, from Pseudomonas sp. Group Ve-2
… into essential amino acids, L-leucine, L-valine, and L-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD+: Part IV. Malate …
Photochemical redox transformations of dimers of NAD+ and N′-methylnicotinamide
The reversible association of quinate: NAD+ oxidoreductase from carrot cells with a putative regulatory subunit depends on light conditions
NAD+ – and NADP+-Dependent Glutamate Dehydrogenases in Nitrobacter agilis
Effect of feeding clofibrate-containing diet on the hepatic NAD+ level in rats
Photoaffinity labeling of ATP and NAD+ binding sites on recombinant human interleukin 2.
High-resolution solid-state carbon-13 NMR. Conformational studies of NADH and NAD+ model systems
Crystallization and preliminary X-ray analysis of an NAD+-dependent alcohol dehydrogenase from the extreme thermophilic archaebacterium Sulfolobus solfataricus
Purification and properties of NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase from spinach leaves
Preparation of analogues of NAD+ as substrates for a sensitive fluorimetric assay of nucleotide pyrophosphatase
On the function of half-site reactivity: intersubunit NAD+-dependent activation of acyl-glyceraldehyde 3-phosphate dehydrogenase reduction by NADH
Purification and properties of NAD+-dependent maltose dehydrogenase produced by alkalophilic Corynebacterium sp. No. 93-1
Macromolecular derivatives of NAD+ in heart nuclei: poly adenosine diphosphoribose and adenosine diphosphoribose proteins
Latex beads phagocytosis capacity and ecto-NAD+ glycohydrolase activity of rat brain microglia cells in vitro
PURIFICATION AND CHARACTERIZATION OF OX BRAIN NAD+ ‐DEPENDENT ISOCITRATE DEHYDROGENASE
Conceptual Error in Determination of NAD+-Malic Enzyme in Extracts Containing NAD+-Malic Dehydrogenase
Acetaldehyde oxidation in Drosophila melanogaster and Drosophila simulans: Evidence for the presence of an NAD+-dependent dehydrogenase
NAD+-dependent formation ofγ-aminobutyrate (GABA) from glutamate
… kinase activity, calmodulin levels during the growth of isolated cells from Lycopersicon pimpinellifolium and kinetic constants of the calmodulin-dependent NAD+ …
Effect of thioridazine or chlorpromazine on increased hepatic NAD+ level in rats fed clofibrate, a hypolipidaemic drug
High surface area catalysts for hydrogen reduction of an enzyme. Reduction of NAD+ to NADH
… spectra of pyridinyl radical dimers detected by reverse pulse polarography. Revised view of the electrochemistry of nicotinamide adenine dinucleotide (NAD+)
Reduction of the pyridine ring of niazid and isoniazid on mercury electrodes. Comparison with other NAD+ model compounds
Effects of molecular weight of dextran and NAD+ density on coenzyme activity of high molecular weight NAD+ derivative covalently bound to dextran
L-fucose metabolism in mammals. Purification of pork liver 2-keto-3-deoxy-L-fuconate: NAD+ oxidoreductase by NAD+-Agarose affinity chromatography
Identification of the Amino Acid Residue Modified in Bacillus stearothermophilus Alcohol Dehydrogenase by the NAD+ Analogue 4‐(3‐Bromoacetylpyridinio) …
Genetic divergence at the NAD+‐dependent malic enzyme locus in Atlantic salmon from Europe and North America
Two NAD+-Isocitrate Dehydrogenase Forms in Phycomyces blakesleeanus. Induction in Response to Acetate Growth and Characterization, Kinetics, and Regulation …
Efficient NAD+-recycling system for ADH-catalysed oxidation in organic media
Streptozotocin, an inducer of NAD+ decrease, attenuates M‐potassium current inhibition by ATP, bradykinin, angiotensin II, endothelin 1 and acetylcholine in NG108 …
Synthesis of Some “Abbreviated” NAD+ Analogues
Regulation of succinate oxidation by NAD+ in mitochondria purified from potato tubers
The redox state of NAD+/NADH systems in rat liver during in vivo inhibition of fatty acid oxidation by adenosine
Determinations of redox states in A2 and B-cell rich islet specimens from guinea pigs, using bioluminescence assay of NAD+ and NADH
Effect of Viologen Structure on Electroreduction of NAD+ Catalyzed by Diaphorase Immobilized on Electrodes
Base interactions in the triplet states of NAD+ and NADH
Molecular orbital study on the interaction between coenzymes and enzymes; NAD+ or NADH and dehydrogenases
Kinetic and physical properties of the l-malate-NAD+ oxidoreductase from Methanospirillum hungatii and comparison with the enzyme from other sources
The role of the nicotinamide moiety of NAD+ for negative cooperativity in glyceraldehyde-3-phosphate dehydrogenase as studied by spin-labeled cofactors
Metabolism of prostaglandins in spontaneously hypertensive rats: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity is decreased in kidney and …
Direct reduction of NAD+ by electrochemical procedure and application of the regenerated NADH to enzyme reaction
O-methylhydroxylamine as a reagent for NAD+ modification in urocanase
The polymorphic ADP-ribosyltransferase (NAD+) pseudogene 1 in humans interrupts an endogenous pol-like element on 13q34
SOME CHARACTERISTICS OF THE D‐GLUCOSE‐6‐PHOSPHATE: CYCLOALDOLASE (NAD+ DEPENDENT) FROM Neurospora crassa *
The stoichiometry of the tightly bound NAD+ in urocanase: Separation and characterization of fully active and inhibited forms of the enzyme
The mechanism of adduct formation between NAD+ and pyruvate bound to pig heart lactate dehydrogenase
NAD+-15-hydroxyprostaglandin dehydrogenase distribution in rat kidney.
Isoenzymes of NADP+-and NAD+-glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in rat adipose tissue
Determination of the absolute configuration of (-)-(2R)-succinic-2-d acid by neutron diffraction study: unambiguous proof of the absolute stereochemistry of the NAD+ …
Recycling of NAD+ crosslinked to albumin or hemoglobin immobilized with multienzyme systems in artificial cells
Inhibition of the GTPase activity of transducin by an NAD+:arginine ADP-ribosyltransferase from turkey erythrocytes
Chemical mechanism of saccharopine dehydrogenase (NAD+, L-lysine-forming) as deduced from initial rate pH studies
Detection of an NAD+-dependent malic enzyme locus in the atlantic salmonSalmo salar and other salmonid fish
The synthesis of deuterium-substituted, spin-labeled analogues of AMP and NAD+ and their use in ESR studies of lactate dehydrogenase
Involvement of Bovine Spleen NAD+ Glycohydrolase in the Metabolism of Cyclic ADP-Ribose-Mechanism of the Cyclization Reaction
Oxidative phosphorylation in fractionated bacterial systems XLIII. Coupling factors associated with the NAD+-linked electron transport pathway
Immobilized thermophilic bacteria as a source of respiratory chain for the recycling of NAD+
… glutamate dehydrogenase by Ellman’s reagent: determination of the enzyme’s dissociation constant for the binary complex with NAD+ from protection studies
Kinetic mechanism of Halobacterium halobium NAD+-glutamate dehydrogenase
Catabolism of NAD+ in rabbit reticulocyte lysates
Regulation of the salvage pathway of purine nucleotide synthesis by the oxidation state of NAD+ in rat heart cells
Properties of the cold-labile NAD+-specific glutamate dehydrogenase from Bacillus cereus DSM 31
Electrochemical Reduction of Nicotinamide Coenzyme (NAD+) Mediated with Rhodium Ion Immobilized in Polymer Modified Electrodes
Rat T cell differentiation alloantigens RT6. 1 and RT6. 2 are NAD+-metabolizing ecto-enzymes that differ in their enzymatic activities
Stereospecificity of hydride transfer for the catalytically recycled NAD+ in CDP-D-glucose 4, 6-dehydratase
Crystallization of NAD+-dependent phenylalanine dehydrogenase from Nocardia sp239
Cellular NAD+ and ATP levels in alkylation-induced cytotoxicity enhanced by an inhibitor of poly (ADP-ribose) synthesis.
Binding of NAD+ to rabbit-muscle glyceraldehydephosphate dehydrogenase. The use of N-methylnicotinamidium chloride as a spectral and conformational probe
ADPRibosylation of chicken red cell tubulin and inhibition of microtubule self-assembly in vitro by the NAD+-dependent avian ADPRibosyl transferase
Synthesis of NAD+ in erythrocytes incubated with nicotinic acid and the effect of di-(2-ethyl hexyl) phthalate (DEHP).
[118] NAD+ kinase from Azotobacter vinelandii and rabbit liver
Immobilized metal-ion affinity partitioning of NAD+-dependent dehydrogenases in poly (ethylene glycol)-dextran two-phase systems
Regulation of a NAD+ kinase activity isolated from asynchronous cultures of the achlorophyllous ZC mutant of Euglena gracilis
Thermodynamic characteristics of NADH/NAD+ analogues in acetonitrile: 2-methyl, 4-methyl and 2,4-dimethyl 1-benzyl-dihydronicotinamides and the corresponding …
HPLC analysis of cyclic adenosine diphosphate ribose and adenosine diphosphate ribose: determination of NAD+ metabolites in hippocampal membranes.
NAD+, ADP-ribosylation and transcription in permeabilized mammalian cells
Inhibition of NADH-dehydrogenase by low concentrations of NAD+
Inhibition of protein synthesis by glucose 6-phosphate and fructose 1, 6-diphosphate in lysed rabbit reticulocytes and the reversal of inhibition by NAD+
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney: II. Kinetic studies
Induction of a decrease in renal NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity by estradiol in rats
Influence of Hyperthermia and γ Radiation on ADP-Ribosyl Transferase, NAD+, and ATP Pools in Human Mononuclear Leukocytes
The synthesis of 15N-and deuterium-substituted, spin-labeled analogues of NAD+ and their use in EPR studies of dehydrogenases
Potentiometric method for subatrate analysis using immobilized NAD+‐dependent oxidoreductase enzymes
Kinetics of NADH oxidation of NAD+ reduction by mitochondrial complex I
Sjögren-Larsson-like syndrome with bone dysplasia and normal fatty alcohol NAD+ oxidoreductase activity
Direct binding of η5-pentamethylcyclopentadienyl-rhodium (III) to nicotinamide cofactors: a step towards NAD+/NADH recycling
An amperometric lactate sensor based on a NAD+‐analog and lactate dehydrogenase coimmobilized on reticulated vitreous carbon
Glutamate deshydrogenase de levure specifique du NAD+: Role du phosphate sur la reaction de desamination oxydative du glutamate
Lipid-membrane characteristics of large lipid-vesicles prepared by two-step emulsification technique and enzymatic NAD+-recycling in the vesicles
Substrate specificity of nine NAD+-dependent alcohol dehydrogenases in Aspergillus nidulans
Comparative studies of NAD+-dependent maltose dehydrogenase and D-glucose dehydrogenase produced by two strains of alkalophilic Corynebacterium …
A new mechanistic model for hydride transfer related to the redox couple NADH/NAD+. Criticism on the quantum‐chemical MO approach
Some properties of mitochondrial NAD+ linked malic enzyme and malate dehydrogenase from the flight muscles of Leptinotarsa decemlineata
[58] dl-Lactate dehydrogenases (NAD+-independent) from Lactobacillus arabinosus
Degradation of (–)-Ephedrine by Pseudomonas putida Detection of (–)-Ephedrine: NAD+-oxidoreductase from Arthrobacter globiformis
Photolabelling of cholera toxin by NAD+
Oxidation of Alcohols via Alkoxymagnesium Halides by an NAD+ Model Compound
Circadian Variations in the Affinities of Nad Kinase and Nadp Phosphatase for their Substrates, NAD+ and Nadp+ in Dividing and Nondividing Cells of the Achlorophyllous Zc …
Conformation about the glycosidic bond: Ribose-nicotinamide of NAD+ bound to some dehydrogenases
Synthesis of spin‐labeled photoaffinity derivatives of NAD+ and their interaction with lactate dehydrogenase
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase: immunochemical characterization of the lung enzyme from pregnant rabbits
Preparative, Electroenzymatic Reduction of NAD+ to NADH on a Thin Poly(Acrylic Acid) Layer-Coated Graphite Felt Electrode Coimmobilizing Ion-paired Methyl …
The photoactivatable NAD+ analogue [32P]2-azido-NAD+ defines intra- and inter-molecular interactions of the C-terminal domain of the G-protein Gαt
Effect of (NH4) 2 SO4 and glycerol on the preservation of the “NAD+-independent” activity of d-glucose-6-phosphate, l-myo-inositol-1-phosphate cycloaldolase from …
Significance of the Zero-Current Potential of the NAD+-NADH system
Reagentless enzyme electrode for glucose-6-phosphate using a mediator-modified graphite electrode and macromolecular NAD+
Specific Intermolecular Association between NAD+ and Rh(terpy)23+
Abbreviated NAD+ Analogues Containinga Phosphonate Function
Spectrofluorometric assay of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity
Action of filipin on phytochrome-modulated D-usnic acid: NAD+ (H) oxido-reductase activity in the lichen Evernia prunastri
Bound NAD+ in glucose 6-phosphate cycloaldolase of Acer pseudoplatanus
The site-selective incorporation of a NAD+ cofactor mimic into a folded helix–loop–helix polypeptide motif
Sex and age differences in the specific activity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase in human fetal kidney tissue
[20] Isolation and properties of an NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from human placenta
NADH production from NAD+ using malic enzyme of Pseudomonas diminuta IFO-13182
NAD+ Glycohydrolase of the Plasma Membrane Prepared from Glial and Neuronal Cells
An Investigation of the Active Site of Lactate Dehydrogenase with NAD+ Analogues
On the participation of adenine reduction in the electrochemical reduction of the coenzyme NAD+
Isolation and characterization of an alkali metal ion-sensitive NAD+-dependent glyceraldehyde 3-phosphate dehydrogenase from germinating green gram (Phaseolus …
Synthesis and purification of deoxyribose analogues of NAD+ by affinity chromatography and strong-anion-exchange high-performance liquid chromatography
A quantitative assay for the cytoplasmic androgen receptor using [3H]dihydrotestosterone in the presence of NAD+-nucleosidase
Candida utilis NAD+ kinase: kinetic and inhibition studies with ADP.
Changes in ovarian NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in pregnant and pseudopregnant rabbits
Pulmonary NAD+-linked 15-hydroxyprostaglandin dehydrogenase activity is decreased by cigarette smoking
Purification, separation, and characterization of two molecular forms of D-1-amino-2-propanol: NAD+ oxidoreductase activity from extracts of Escherichia coli …
Chicken liver xanthine dehydrogenase kinetic behaviour with oxygen or NAD+ as electron acceptors
Peroxidase activity of horse liver alcohol dehydrogenase in the presence of β-NAD+ and hydrogen peroxide
Crystallization of NAD+ synthetase from Bacillus subtilis
Fate of ecto‐NAD+ glycohydrolase during phagocytosis of normal and mannosylated latex beads by murine macrophages
Purification of an NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from the human placenta
Regulation of NAD+‐ and NADP+‐linked isocitrate dehydrogenase in the obligate methylotrophic bacterium Pseudomonas W6
Hexose metabolism in pancreatic islets: regulation of the mitochondrial NADH/NAD+ ratio
The application of continuous monitoring microdensitometry to an analysis of NAD+ binding and 3β-hydroxy-Δ5-steroid dehydrogenase activity in the regressing …
Coupling of uridine-5′-diphosphate (UDP) formation and nicotinamide adenine dinucleotide (NAD+) reduction for cytochemical localization of …
Calcium inhibition of the NAD+-linked isocitrate dehydrogenase from blowfly flight muscle mitochondria.
On the mechanism of rotenone‐insensitive reduction of quinones by mitochondrial NADH:ubiquinone reductase The high affinity binding of NAD+ and NADH to the …
Regulation of Rates of Ethanol Metabolism and Liver [NAD+]/[NADH] Ratio
NADH production from NAD+ with a formate dehydrogenase system involving immobilized cells of a methylotrophic Arthrobacter strain
Occurrence of two NAD+-linked malate dehydrogenase isozymes in Euglena gracilis
PHOSPHORESCENCE MAXIMA AND TRIPLET STATE LIFETIMES OF NAD+ AND ε‐NAD+ IN TERNARY COMPLEXES WITH HORSE LIVER ALCOHOL …
Effect of High Physiological Temperatures on NAD+ Content of Green Leaf Mitochondria (Apparent Inhibition of Glycine Oxidation)
Renal gluconeogenesis and mitochondrial NAD+-NADH ratios in nursing and adult rats
Methods to extract NAD+‐malate dehydrogenase efficiently from white spruce needles
Investigation of the reduction mechanism of the NAD+ model compound N’-methyl nicotinamide on mercury electrodes in strongly acidic solutions
An unassembled subunit of NAD+-dependent isocitrate dehydrogenase is insoluble and covalently modified
Purification and characterisation of an NAD+-dependent secondary alcohol dehydrogenase from Pseudomonas maltophilia MB11L
Isolation of rat renal NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Coenzyme production using immobilized enzymes. I. Preparation, characterization, and laboratory-scale application of an immobilized NAD+ kinase
NAD+-dependent ethanol oxidation: redox effects and rate limitation
5β-Cholestane-3α, 7α, 12α, 26-tetrol: NAD+ oxidoreductase and 5β-cholestane-3α, 7α, 12α-triol-26-al: NAD+ oxidoreductase in rat liver
Application of High Enzyme Activities Present in Clostridium Thermoaceticum for the Efficient Regeneration of NADPH, NADP+, NADH AND NAD+
Corner-cutting tunneling in hydride transfer between NAD+ analogues
NAD+ kinase activities in Euglena gracilis and Phaseolus vulgaris
A pyrophosphatase which degrades NAD+ is located on the external surface of cultured fibroblasts: Evidence that NAD+ is not extruded during treatment with N …
Sequential conformational changes with the binding of NAD+ to rabbit muscle glyceraldehyde-3-phosphate dehydrogenase
In vitro drug delivery mediated by ecto-NAD+-glycohydrolase ligand-targeted liposomes
… . The enzymes from the thermoacidophilic organisms Sulfolobus acidocaldarius and Thermoplasma acidophilum show A-side stereospecificity for NAD+.
Stimulation by arsenate of ATP-driven energy-linked reduction of NAD+ by succinate
Cysteinyl peptide labeled by 3-bromo-2-ketoglutarate in the active site of pig heart NAD+-dependent isocitrate dehydrogenase
Implication of a tyrosyl residue at the active site of mitochondrial l-Malate: NAD+ oxidoreductase
Transcription of Mouse Ribosomal RNA Gene with Inactive Extracts Is Activated by NAD+In Vitro
[15] NAD+ kinase from sea urchin eggs
Possible Model of Liver Carcinogenesis Using Inhibitors of NAD+ ADP Ribosyl Transferase in Rats
NAD+-dependent hydrogenase from the hydrogen oxidizing bacterium Alcaligenes eutrophus Z1. Stabilization against temperature and urea induced inactivation
Adaptive changes in NAD+ metabolism in ultraviolet light-irradiated murine lymphoma cells
Acute Stimulation of Thyroidal NAD+ Kinase, NADPH Reoxidation, and Peroxidase Activities by Physiological Concentrations of Thyroid Stimulating Hormone Acting …
Preparation and kinetic properties of 5‐ethylphenazine‐glucose‐dehydrogenase‐NAD+ conjugate, a semisynthetic glucose oxidase
Photodependent inhibition of rat liver NAD (P) H: quinone acceptor oxidoreductase by (A)-2-azido-NAD+ and (A)-8-azido-NAD+
Reactivation of NAD(H) biosynthetic pathway by exogenous NAD+ in nil cells severely depleted of NAD(H)
Effect of an anti-ulcer drug, plaunotol, and its metabolites on NAD+ dependent 15-hydroxyprostaglandin dehydrogenase from gastric mucosa
Flavin plus 5-deazaflavin as a turnover oxidation system: model for the electron bridge from NAD+ to flavin
Succinate Semialdehyde Dehydrogenase of Rhodopseudomonas spheroides which is Active with Both NADP+ and NAD+
Drug effects on retinol oxidation: retinal alcohol: NAD+ oxidoreductase
[27] Covalent modification of proteins by metabolites of NAD+
Preparation and kinetic properties of 5‐ethylphenazine–lactate‐dehydrogenase–NAD+ conjugate, a semisynthetic lactate oxidase showing a hide‐and‐seek effect
Coenzyme models. 28. Facile oxidation of alcohols and amines by 3-hydroxy-N-methylacridinium ion, a new NAD+ model compound
Photodependent inhibition of bovine spleen NAD+ glycohydrolase by 8-azido carbocyclic analogs of NAD+
Studies on NAD+ permeability in intact mitochondria from rabbit reticulocytes.
The effect of chloride on the electroreduction of NAD+ in the presence of [Cp* RhIII] 2+ species
The binding of spin-labeled derivatives of NAD+ and its structural components to pig skeletal muscle lactate dehydrogenase
Differential pulse polarography as a tool for the determination of trace levels of nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide …
The metabolism of prostaglandin D2 evidence for the sequential conversion by NADPH and NAD+ dependent pathways
Purification and characterization of an NAD+-linked formaldehyde dehydrogenase from the facultative RuMP cycle methylotrophArthrobacter P1
Synthesis and chiroptical properties of some abbreviated NAD+ analogues
[108] Preparation and properties of α-NAD+ and α-NADH
[22] myo-Inositol: NAD+ 2-oxidoreductase
Purification and characterization of an NAD+-dependent dehydrogenase that catalyzes the oxidation of thromboxane B2 at C-11 from porcine liver. Development and …
Stimulation of Mg2+-dependent endonuclease activity of rat testis nuclei on incubation with NAD+ in vitro
Serum proteins with NAD+ glycohydrolase activity and anti-CD38 reactivity–elevated levels in serum of tumour patients
[7] Synthesis and use of radioactive photoactivatable NAD+ derivatives as probes for G-protein structure
Rotational barriers of 1, 3-substituted pyridines and benzenes as models for the NAD+/NADH coenzyme
The influence of NAD+-linked substrates on energy conservation at sites 2 and 3 in mitochondria treated with inorganic arsenate
Glycoxylic acid prevents NAD+ and NADH depletion in K562 cells cultured at limiting dilution
Photochemical reduction of NAD+ to 1, 4-NADH without an enzyme
NAD+/NADP+-dependent malic enzyme: evidence of a NADP+ preferring activity in human skeletal muscle
Bovine Liver Mitochondrial NAD+ Glycohydrolase: Relationship to ADP-Ribosylation and Calcium Fluxes
NAD+ binding by yeast alcohol dehydro-genase in the presence of pyrazole and a new method for the determination of the enzyme active site concentration
Kinetic studies on the binding of 1, N6-etheno-NAD+ to glutamate dehydrogenase from Clostridium symbiosum
Reduction of NAD+ by the reversed respiratory electron flow in Azotobacter vinelandii
NAD+-linked isocitrate dehydrogenase in fish tissues
On the biological role of the nuclear polymerizing NAD+: protein (ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the …
The effect of NADH and NAD+ on the proteolysis of lactate dehydrogenase isozymes by trypsin
Efficient NAD+-Regeneration System with Heterocyclic o-Quinones and Molecular Oxygen Catalyzed by Diaphorase
Regio-specific behaviour in electrochemical two-electron reduction of NAD+ analogs
A Kinetic Study on the Binding of Monomeric and Polymeric Derivatives of NAD + to Yeast Alcohol Dehydrogenase
Stabilization of NAD+‐dependent dehydrogenases and diaphorase by bilayer encagement
A general colorimetric procedure using oxidized chlorpromazine hydrochloride for the estimation Of enzymes dependent on NADH/NAD+ and NADPH/NADP+ …
Requirement of down‐regulation of NAD+ ADP‐ribosyltransferase for the interferon‐γ‐induced activation process of murine macrophage tumor cells
Enzyme electrode based on gold-plated polyester cloth: 2. NAD+ and NADH regeneration by diaphorase-immobilized electrode
Electron exchange and photoreduction of NAD+ and NADP+
Electroanalytical Study on Nicotinamide 7-Methylguanine Dinucleotide (Nm7GD+), Analog of Coenzyme NAD+ and Related Compounds
Enzyme-like Reaction Catalyzed by NAD+–Reduced Keratin Systems
A novel spectrophotometric method for the enzymatic determination of NAD+ and NADH.
Effects of 1, 2-dihydro-4-hydroxy-6-methoxy-N-methyl quinoline in relation to circadian rhythms of NAD+ kinase and NADP+ autoreduction in Neurospora crassa and …
Signal Transduction Via the CD38/NAD+ Glycohydrolase
Sodium Nitroprusside Promotes NAD+ Labeling of a 116-kDa Protein in NG108-15 Cell Homogenates
Energy-linked reactions in photosynthetic bacteria: VII. Inhibition of NAD+ reduction by phenethylbiguanide
High-performance liquid chromatography separation of some NAD+ derivatives suitable for covalent binding
Conformational energy calculations for dinucleotide molecules: A study of the nucleotide coenzyme nicotinamide adenine dinucleotide (NAD+)
Monoelectronic reduction of 1-alkyl-3, 5-di (alkylcarbamoyl) pyridinium ions as a model of the NAD+/NADH system: Obtaining 1, 4-dihydropyridines
Determination of the absolute stereospecificity of the enzymatic reduction of NAD+ analogs by means of the primary acid cyclization reaction
Regioselective addition of 2-nitropropane anion to NAD+ analogues
[29] Use of differently immobilized nucleotides for binding NAD+-dependent dehydrogenases
DNA-Damage and NAD+-Depletion are Initial Events in Oxygen Radical Induced Islet Cell Death
Molecular Biology of Human Nuclear NAD+: ADPRibosyl-transferase (polymerizing)
NAD+ kinase: molecular weight determination by low‐angle laser‐light scattering
A coupled NAD+-peroxidase spectrophotometric assay for cholesterol.
The binding of NAD+ and NADH to glyceraldehydephosphate dehydrogenase
Intracellular NAD+ content and ADP‐ribose polymerase activity of serum‐stimulated baby hamster kidney fibroblasts
Characterization of Hydrosoluble and Detergent-Solubilized Forms of Mitochondrial NAD+ Glycohydrolase from Bovine Liver
… of ADP-ribosyltransferase inhibitors on the intracellular NAD and ATP levels in Ehrlich ascites tumor cells: implication for the altered NAD+ ATP-dependent cellular …
Differential Effect of Benzamide on NAD+ Content and the Frequency of Chromatid Aberrations in X-Irradiated L5178Y-R and L5178Y-S Cells
Sources of alcohol dehydrogenase (NAD+-linked) in the cockroach, Leucophaea maderae
Influence of NAD+ on development of mouse blastocysts in vitro
Enzymatic “In Vitro” Reduction Of Ketones. V. (1) Reduction of 1‐alkyl‐4‐piperidones in an ethanol ‐ NAD+ ‐ HLAD ‐ system
FACILE OXIDATION OF ALCOHOLS BY 3-HYDROXY-N-METHYLACRIDINIUM ION (A NEW NAD+ MODEL COMPOUND)
Inhibition Studies of Dehydrogenases by Structural Analogues of NAD+
Immobilization ofmyo-inositol-1-phosphate synthase containing active, self-regenerating coenzyme (NAD+) on the same matrix
Conformation of NAD+ in solution, in holoenzymes and in the crystalline Li+-complex
The contribution of tryptophan to the regulation of the NAD+ level in mouse liver.
NAD+ analogue binding to glyceraldehyde‐3‐phosphate dehydrogenase
Xanthine: NAD+ oxidoreductase in the liver of grass snake Natrix natrix.
Substrate oxidation and NAD+ reduction by phototrophic bacteria
Asymmetric reassociation of calf spleen NAD+ glycohydrolase into liposomes
On the Mechanism of the Urocanase Reaction: Confirmation of the Structure of the NAD+‐Inhibitor Adduct by Direct 13C‐13C Coupling
On the Mechanism of Action of Urocanase: Observation of the Enzyme‐Bound NAD+ ‐Inhibitor Adduct by 13C NMR Spectroscopy
Hydrosoluble polymers of NAD+ and ADP. Study of their coenzymatic properties as a function of their size
… activities of the mitochondrial reduced nicotinamide adenine dinucleotide-ubiquinone reductase (complex I) utilizing arylazido-β-alanyl NAD+ and arylazido-β-alanyl …
[28] Coenzyme activity of NAD+ bound to polymer supports through the adenine moiety
Effects of steroids on renal NAD+-dependent 15-hydroxy-prostaglandin dehydrogenase activity in ovariectomized rats
Mouse RT6 Locus 1 and RAT RT6.2 are NAD+ Arginine ADP-Ribosyltransferases with Auto-ADP-Ribosylation Activity
Properties of 3-aldoxime pyridine adenine dinucleotide, an NAD+ analogue
Purification and Immunological Properties of NAD+-linked Malate Dehydrogenase Isozymes from Euglena gracilis
On the electrochemical behaviour in aprotic media of dihydropyridines and tetrahydrobipyridines derived from NAD+ model compounds
Relationship between NAD+/NADH Levels and Animal Cell Growth
… -3-carbamoylpyridinium: Indole-3-acetic acid (1: 1) monohydrate complex. A model for the intermolecular stacking interaction between the indole ring and NAD+
Distribution of NAD+-dependent prostaglandin dehydrogenase activity among human fetal tissues
NAD+-dependent formation of 2-amino-4-hydroxy-6-carboxypteridine from 2-amino-4-hydroxy-6-formylpteridine by cell-free extracts of Escherichia coli
Conversion of Ammonia to Glutamate by L-Glutamic Dehydrogenase, Alcohol Dehydrogenase and NAD+ Immobilized within Lipid-Polyamide Polyethyleneimine …
Conservation of sequences between human and gorilla lineages: ADP-ribosyltransferase (NAD+) pseudogene 1 and neighboring retroposons
Die Wirkung von Blei auf die NAD+-abhängige Malat-Dehydrogenase in Medicago sativa L. and Zebrina pendula SCHNIZL: The Effect of Lead on the NAD+ …
NAD+ induced nucleoside specificity of oxidative phosphorylation
Comparison of xanthine: NAD+ oxidoreductase from liver of toad Bufo viridis and other vertebrates.
Ion-pair reverse-phase high-performance liquid chromatography. Application to the study of chicken liver NAD+ kinase
NAD+-braking action of ascorbic acid in the presence of Cu2+
[22] Microassay procedure for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
NAD+ loading of mammalian cells by electrotransfection leads to increased poly (ADP-ribosyl) ation capacity
Rat testis mitochondrial aldehyde dehydrogenase: kinetic evidence for a direct reaction between capronaldehyde and enzyme-bound NAD+ in the presence of Mg2+ …
Hydroperoxide Inhibitor of Horse Liver Alcohol Dehydrogenase Activity, Tightly Bound to the Enzyme-NAD+ Complex, Characteristically Degrades the Coenzyme
NAD+-kinase from Neurospora crassa: isolation and properties
NAD+ kinase in the development of a silkworm, Bombyx mori L.
Voltammetric behavior studies on the interaction between lanthanide ions and NAD+, NAD-LDH complex
Reductive Methylation of NAD+ Analogues by a trans-Dimethylcobalt(III) Complex
[59] NAD+-dependent retinol dehydrogenase in liver microsomes
A Molecular Orbital Study on the Approach of Hydride Ion to NAD+ as a Coenzyme
Synthesis and Application of Matrix Bound AMP, NAD+ and Other Adenine Nucleotides
Symmetry and NAD+-dependent structural changes in d-glyceraldehyde-3-phosphate dehydrogenase
Synthesis of Novel Spin-Labeled Photoaffinity Derivatives of NAD+ and ATP and Their Characterization as Coenzymes and Substrates of Several Enzymes
Photocatalyzed Anaerobic Oxidation of Nicotinamide Coenzyme Dimers to NAD+ by Adriamycin
Chemical and structural relationships of NAD+ and platinum binding to malate dehydrogenase
Streptococcal extracellular NAD+ nucleosidase. Characterization of changes occurring during purification
Succinate-dependent NAD+ reduction by the reversed respiratory electron transport in Bradyrhizobium japonicum
The Role of NAD+ in the Catalytic Mechanism of Lipoamide Dehydrogenase
The effects of silica on the free, apparent redox state (NAD+/NADH) of the alveolar macrophage; a possible mitochondrial membrane effect
Effect of aluminium on the NAD+ kinase activity of Euglena gracilis grown heterotrophically
Electrochemical and spectroscopic study of redox transformation of the 7-methylguanine analog of coenzyme NAD+
Adriamycin-catalyzed aerobic photooxidation of NAD dimers to NAD+
Expression of the cDNA for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase as a catalytically active enzyme in Escherichia coli
Monitoring enzymic peroxidation of NAD+ by capillary electrophoresis
Purification and properties of a nucleoside diphosphosugar: NAD+ 2-hexosyl oxidoreductase
Chilling followed by incubation at 37 C causes a reduction in NAD+ levels which can be prevented by the poly (ADP-ribose) transferase inhibitor 3-aminobenzamide
On the redox state of NAD+/NADH systems in guinea pig liver under different experimental conditions
Electrospray mass spectral analysis of the (N)-arylazido-β-alanyl NAD+ modified bovine heart mitochondrial NADH dehydrogenase
Analysis of the interactions of NAD+ with horse liver alcohol dehydrogenase using molecular mechanics
Conformational preference and rotational barriers in NAD+ model systems. Temperature dependence of NMR spectra for some N‐aralkylpyridinium ions
Cathodic Reduction of Nicotinamide Coenzyme (NAD+) Mediated with Rhodium Complex Immobilized on Electrode Surface
Isoproterenol-stimulated labelling of particulate proteins by using [adenylate-32P] NAD+ independent on a cAMP-dependent protein kinase in parotid acinar ells
Fine Control of Regioselectivity in the Reduction of NAD+ Analogues by Ketene Silyl Acetals
Photodependent incorporation of arylazido-β-alanyl-NAD+ into the coenzyme binding site of yeast glyceraldehyde-3-phosphate dehydrogenase
A 3-aminobenzamide-resistant labeled protein in [32P] NAD+-labeled cells
Modeling of NAD+ analogues in horse liver alcohol dehydrogenase
Temperature dependence of the primary kinetic isotope effect in hydride transfer reactions with NAD+ and NADH models
TR-NOE NMR study of the E. coli wild-type GAPDH and its THR 313 mutant/ NAD+ complex
An NMR study of 1H and 31P relaxation and molecular dynamics in polycrystalline nicotinamide adenine dinucleotide (NAD+)
[NAD+]/[NADH] redox-state metabolites of freezed-clamped livers of rats fed casein or gelatin diets
Investigation on Photochemical Reduction of NAD+ to NADH in Liposomal Solution
Sterospecificity of NAD+/NADH reactions: A project experiment for advanced undergraduates
The behaviour of NAD+ and NADH inAcinetobacter calcoaceticus duringn-alkane assimilation
Interaction and activities of NAD+ and NAD+ analogs with four dehydrogenases
ΔpH driven energy-linked NAD+ reduction in Rhodospirillum rubrum chromatophores
Spectroscopic characterization of a functionalized NAD+ analogue and its polyethyleneimine-bound derivative
Kinetics of alpha-dicarbonyls reduction by L-glycol dehydrogenase (NAD+) from Enterobacter aerogenes.
β‐NAD+ and its stack interaction
Xanthine: NAD+ oxidoreductase from embryo liver of hen Gallus gallus
Bioelectrocatalytic Reduction of NAD+ Using Baker’s Yeast
Coenzyme Modeis 17. Is 5-Deazaflavin a Model for NAD+? Comment on
Binding of Inhibiting Adducts of Ketones and NAD+ to Alcohol Dehydrogenase fromDrosophila melanogaster
The electron-accepting strength of NAD+
NAD+-linked formate dehydrogenase from Alcaligenes eutrophus: a molybdo-iron-sulfur-flavo protein
Comparison of xanthine: NAD+ oxidoreductase from liver of two uricotelic species: hen Gallus gallus and snake Natrix natrix.
The Effect of Ligands on the Irreversible Inhibition of the NAD+‐Dependent Isocitrate Dehydrogenase from Ox Brain
Specific binding of nucleotides and NAD+ to Clostridium difficile toxin A
… -mediated reactions. Part 11. Experiments on the dismutation of aldehyde to alcohol and carboxylic acid by the complex of liver alcohol dehydrogenase and NAD+
The cytochemical assay of NAD+ kinase activity in the follicular cells of guinea-pig thyroid gland
Electrochemical behaviour of 1-alkyl-3, 5-di (alkylcarbamoyl) pyridinium ions as a model of the NAD+/NADH system in aqueous solution
Photoaffinity Labeling of Lactate Dehydrogenase by the Bis-azido Analog of NAD+: P1-N6-(4-azidopheny lethyl) adenosine-P2-[4-(3-azidopyridinio) butyl] …
Solvent effects in 5-deazaflavin oxidation as a model for NAD+ dependent enzymes
Spectrophotometric determination of cyanide based on the formation of NAD+-cyanide addition compound
Synthesis and Properties of 7-Acetyl-1, N6-etheno-AMP and 7-Acetyl-1, N6-etheno-NAD+
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in kidney tissue from NZB/NZW F1 hybrid mice.
Evidence for several fold more activity of NAD+-dependent uterine prostaglandin 15-hydroydehydrogenase in transsexual than in non-transsexual women
Metabolic conversions of NAD+ and cyclic ADP ribose at the outer surface of human red blood cells
Assignment of FRA1H common fragile site to human chromosome band 1q42. 1 proximal to the nuclear NAD+ ADP-ribosyltransferase gene (ADPRT) and to the main …
Synthesis and Kinetic Properties of a New NAD+ Derivative Carrying a Vinyl Group
New Reactive Coenzyme Analogues for Affinity Labeling of NAD+ and NADP+ Dependent Dehydrogenases
Structure of the Dimers Obtained From the Reduction of 1‐Benzyl‐3,5‐bis(dialkylcarbamoyl)pyridinium Ions – Models of NAD+
The response of plant NAD+ kinase to abiotic stresses.
Trevor Slater, Free Radical Redox Chemistry and Antioxidants: from NAD+ and Vitamin C TO CCl4 and Vitamin E, to Thiols, Myoglobin and Vitamins A and D
[21] Assay of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase using (15S)-[15-3H] PGE2
Transfer of hydrogen from NADPH to NAD+ in frozen aqueous solution
Spectral evidence for an intermediate in the glutamate dehydrogenase catalyzed reduction of NAD+ by glutamate
Effect of mercaptoethanol in the radioactive thin layer chromatography assay of NAD+-15-hydroxyprostagland in dehydrogenase
Aldehyde dehydrogenase activities and NAD+-dependent formaldehyde oxidation in perivenous and periportal hepatocytes: effect of induction by beta …
Identification of essential amino acids in the active center of thyroidal NAD+ glycohydrolase.
AN 125I‐LABELED N6‐SUBSTITUTED AZIDO ANALOG OF NAD+ FOR THE PHOTOAFFINITY LABELING OF NAD+‐LINKED ENZYMES
An increase of NAD+ kinase activity in Neurospora cells during adaptation to environmental stress
Purification and immobilization of NAD+ synthetase from Escherichia coli
NAD+ analogs in formation of new fluorophores on ultraviolet irradiation with D-glyceraldehyde-3-phosphate dehydrogenase.
Analysis of NAD+ in picomole amounts with sodium [32P] pyrophosphate and NAD-pyrophosphorylase
Subband formation of human LDH isozyme with contaminants of commercial β-NAD+ sample
In Vitro ADP-Ribosylation Utilizing 2′Deoxy-NAD+ as a Substrate
Enzymatic determination of anti-NAD+ glycohydrolase in serum
NAD+ and NADH in brain cortex from mice exposed to high oxygen pressure
Rat survival and mitochondrial ratio of free NAD+/NADH in the liver under the effect of ionizing radiation and sodium succinate
[Correlation between [NAD+]:[NADH] and the” phosphate potential” in liver cytoplasm of developing chicken embryos].
Tricho monas vaginalis: Localization and character ization of malate dehydrogenase and NAD+-linked malic enzyme
The Pressure Dependence of the Rotation of the N-Aralkyl-pyridinium Moiety in a Synthetic NAD+ Model System Studied by High Pressure HRNMR
The synthesis of a bisphosphonate carbocyclic NAD+ analogue for the investigation of ADP-ribosyl cyclase
The analysis of transients in NAD+-linked dehydrogenases
Activation of complex I in the reaction of NADH oxidation and delta mu H+-dependent NAD+ reduction by succinate
Properties of native calf spleen NAD+ glycohydrolase immobilized by hydrophobic interaction.
Divergency of structure and function of vertebrate xanthine: NAD+ oxidoreductase.
The influence of chronic cobalt poisoning on glycogen content and isoenzymic patterns of lactate dehydrogenase (LDH) and NAD+-dependent malate dehydrogenase …
Amplified Detection of NAD+ and NADH by the Enzymatic Cycling with the Use of Immobilized Enzymes in a Flow System
Cloning, Expression and Site-Directed Mutagenesis of the cDNA for Human Placental NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase
Total LDH activity and its fractions (L-lactate: NAD+-oxidoreductase, EC 1.1. 1.27) in amniotic fluid and serum in high risk pregnancies.
Determination of L-lactate: NAD+-oxidoreductase (EC 1.1. 1.27) and its isoenzymes during pregnancy.
Photoaffinity labelling of lactate dehydrogenase from pig heart with a bifunctional NAD+-analogue
REACTIONS OF NAD+-MODEL COMPOUNDS WITH BASE. THE REVISED STRUCTURE OF DITTMER’S TRIMER
Temperature dependence of difference‐absorption coefficients of NADH minus NAD+ and NADPH minus NADP+ in the near ultraviolet
The effect of NO2 on erythrocyte glucose metabolism as related to changes in redox ratio [NAD+][NADH]
REGULATION OF PROTEIN SYNTHESIS: ROLE OF NAD+ AND SUGAR PHOSPHATES IN LYSED RABBIT RETICULOCYTES
Differential binding of NAD+ to acyl glyceraldehyde-3-phosphate dehydrogenase and its role in the acyl group transfer reaction.
[17] Photoaffinity labeling of NAD+-linked enzymes
Polymères hydrosolubles de NAD+ et d’ADP: Etude de leurs propriétés coenzymatiques en fonction de leur taille
NAD+ synthesis in the isolated kidney cell nuclei of dogs after the intravenous administration of amphotericin B
Dynamics of the NADP+ and NAD+ levels in the mycelium of P. nigricans Thom strains of varying productivity depending on the carbon source
Temperature effects at the NADP+ and NAD+ levels in the mycelium of P. nigricans Thom. strains grown on different carbon sources
Purification of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney
Metabolism of NAD+ in the nuclei of human placenta
Kinetics of IMP: NAD+ oxidoreductase in serum of normal Iraqi individuals.
Effect of additions of the carbon and nitrogen sources on the NADP+ and NAD+ level in the mycelium of a producing strain of P. nigricans Thom
Synthesis and characterisation of a flourinated analogue of NAD+
Independence of the (NAD+):(NADH) ratio from the adenylic system in the liver cytoplasm of the developing chick embryo
The relationship between the (NAD+)/(NAD-H) ratio and the adenylate system in the cytoplasm of loach oocytes and embryos
Dipodascus magnusii (Saccharomycetes) contains multiple glucose-6-phosphate dehydrogenases with different NAD+/NADP+ dependencies.
Enzymes of NAD+ catabolism in differentiating rabbit erythroid cells
5β-CHOLESTANE-3α, 27-DIOL: NAD+ OXIDOREDUCTASE AND 3α-HYDROXY-5β-CHOLESTAN-27-AL: NAD+ OXIDOREDUCTASE IN RAT LIVER EXTRACT
15-Hydroxyprostaglandin dehydrogenase (NAD+)
NAD+ Biosynthesis in Human Placenta: Characterization of Homogeneous NMN Adenylyltransferase
GTP-dependent modification of a 21-kDa substrate with NAD+ in bovine brain soluble fraction is not ADP-ribosylation of small G-protein but tailing of tRNA
The Fertility Expression of Dual-purpose Genic Male Sterile Line Indica Rice Pei’ai 64S: Changes of NAD+-MDH and AP Isoenzyme during Spikelet Development
Muscle Glyceraldehydephosphate Dehydrogenase: NAD+ Binding and its Implications for the Mechanism of Action of the Enzyme
Amperometric biosensors based on electrocatalytic regeneration of NAD+ at redox polymer-modified electrodes* zyxwvutsrqponmlkjihgfedcb
A new ternary complex between horse liver alcohol dehydrogenase, NAD+, and acetone
NAD+/NADH ratio in the mitochondria of the oocytes and ova of groundling, Misgurnus fossilis (L.)
Xanthine oxidase activity: NAD+-dependent and O2-dependent forms in carrageenan granuloma in the rat
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from the human term placenta
Xanthine oxidase activity: O2-dependent and NAD+-dependent forms in the liver, in rats with adjuvant arthritis and hepatitis
Hysteresis behavior of complex I in delta mu H+-dependent reduction of NAD+ succinate
Specificity of 3 alpha, 20 beta-hydroxysteroid: NAD+-oxidoreductase (author’s transl)
The importance of the position of the adenosine linkage in NAD+ for its coenzyme activity via lactate dehydrogenase (author’s transl)
Characteristic features of the function of the NAD+-and NADP+-dehydrogenase systems in the milk of cows with different levels of milk production
I3 C NMR Spectroscopy of Some Pyrimidine Nucleosides, 5′-AMP-di-Na-Salt, NAD+ and NADH-di-Na-Salt. The Analysis of Coupling Constants 3 J I3 C 6-HI’, 3 J I3 C …
Enzymatic NAD + Recycling in Large Liposomes Prepared by Means of the Two-Step Emulsification Procedure
Mechanism of Action of Urocanase: Ruling Out a 1, 5 Sigmatropic H-Shift in the Intermediate NAD+ Urocanate Adduct
Substrate-selective photo-oxidation of benzyl alcohol derivatives with oxygen, catalysed by an NAD+ model compound
Conformational Effects of NAD+ on Yeast Glyceraldehyde-3-Phosphate Dehydrogenase
Characteristics of Enzymatic NAD+-Recycling Reaction In Microcapsule Of Liquid-Surfactant Membrane
Genetic variation and immunochemical properties of L-malate: NAD+ oxidoreductase isozymes in the bandicoot, Isoodon macrourus.
Influence of urea and organic solvents on the activity of immobilizedmyo-inositol-1-phosphate synthase containing active, self-regenerating coenzyme (NAD+) on the …
A study of Neurospora genes encoding NAD+-specific glutamate dehydrogenase (gdh) and heat shock protein 80 (hspe-1) by repeat-induced point mutations
… NAD+. NADP+(nicotinamide adenine dinucleotide phosphate, triphosphopyridine nucleotide, TPN). NADP+ has the same chemical structure as NAD+ except for an …
MACROMOLECULAR NAD+-DERIVATIVE OF HIGH COENZYME ACTIVITY AND ITS APPLICATION FOR A MODEL REACTION
Saccharopine dehydrogenase (NAD+, L-lysine forming)
Utilization of Glycerol as Hydrogen Acceptor by Lactobacillus reuteri: Purification of 1, 3-Propanediol: NAD+ Oxidoreductaset
NAD+ 57 Na-K-ATase 71 see phosphofructokinase see Pyruvate pH effects 69
Synthesis and structure-reactivity studies of 2′-substituted nicotinamide nucleoside analogs of NAD+
Glycerol-3-phosphate dehydrogenase (NAD+)
REDOX-PHOTOSENSITIZED REACTIONS OF AN NAD+/NADH MODEL AND RELATED COMPOUNDS BY Ru (II) AND Re (I) 2, 2′-BIPYRIDINE COMPLEXES
Regulation of glutamate dehydrogenase synthesis, and studies on subunit structure and properties of NAD+-specific glutamate dehydrogenase in Neurospora crassa
Déshydrogénases réduisant le NAD+ en présence du d (—) 3-phosphoglycérate chez les mycobactéries (BCG, H37Ra, M. phlei)
Artificial cells containing multienzyme systems with dextran-NAD+ recycling for the conversion of Ammonia and urea into L-amino acids especially essential amino …
… Studies Supporting the Medical Chemical Defense Program. Time and Dose Response Characterization of the Prevention of HD-Induced NAD+ Depletion and HD …
THE BINDING OF ACONITASE,(NAD+) ISOCITRATE DEHYDROGENASE, AND (NADP+) ISOCITRATE DEHYDROGENASE TO THE INNER MEMBRANES …
Alkaline phosphatase activity in relation to LDH5 (L-lactate: NAD+-oxidoreductase, EC 1.1. 1.27) in patients with precancerous conditions of the endometrium.
NUCLEAR MAGNETIC RESONANCE (NMR) AND POLAROGRAPHIC STUDIES OF SELECTED NAD+ AND NADP+ MODEL COMPOUNDS.
The effect of phosphorylation on oxidative and CoA-and NAD+-independent turnover of pyruvate by pyruvate dehydrogenase complex in the brain
Soluble NAD+-Derivatives of High Molecular Weight in Enzymic Recycling Systems
NAD+ ADP-ribosyltransferase
Marcus Theory of a Parallel Effect on a for Hydride Transfer Reaction between NAD+ Analogues
NAD+ metabolism in health and disease
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
NAD+ and NADH in cellular functions and cell death
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet-and age-induced diabetes in mice
Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of …
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
NAD+ depletion is necessary and sufficient forPoly (ADP-ribose) polymerase-1-mediated neuronal death
Connexin 43 hemichannels mediate Ca2+‐regulated transmembrane NAD+ fluxes in intact cells
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
Poly (ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis
Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
NAD+ and vitamin B3: from metabolism to therapies
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
NAD+-Dependent Deacetylase Hst1p Controls Biosynthesis and Cellular NAD+ Levels in Saccharomyces cerevisiae
Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition
NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels
NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes
Poly (ADP-ribosyl) ation by PARP-1:PAR-laying’NAD+ into a nuclear signal
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
Imaging cytosolic NADH-NAD+ redox state with a genetically encoded fluorescent biosensor
NAD+ and NADH in brain functions, brain diseases and brain aging
Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against Excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger …
Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae
Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor
Enzymology of NAD+ homeostasis in man
Role of NAD+ in the deacetylase activity of the SIR2-like proteins
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD+ Synthesis in Cardiac Myocytes
Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD+ and inhibition of glycolysis
Metabolic engineering of Escherichia coli: increase of NADH availability by overexpressing an NAD+-dependent formate dehydrogenase
Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1
Mechanism of sirtuin inhibition by nicotinamide: altering the NAD+ cosubstrate specificity of a Sir2 enzyme
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD+
Chemistry of Gene Silencing: The Mechanism of NAD+-Dependent Deacetylation Reactions
SIRT1-dependent regulation of chromatin and transcription: linking NAD+ metabolism and signaling to the control of cellular functions
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway
NAD+ as a metabolic link between DNA damage and cell death
The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient …
Compartmentation of NAD+-dependent signalling
Substrate Specificity and Kinetic Mechanism of the Sir2 Family of NAD+-Dependent Histone/Protein Deacetylases
NAD+ released during inflammation participates in T cell homeostasis by inducing ART2-mediated death of naive T cells in vivo
NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway
Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin
Intra-mitochondrial poly (ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress
A novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3 (2)
NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance
Bioorganometallic Chemistry. 13. Regioselective Reduction of NAD+ Models, 1-Benzylnicotinamde Triflate and β-Nicotinamide Ribose-5′-methyl Phosphate, with in Situ …
Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins
Enzymology of NAD+ synthesis
Linking chromatin function with metabolic networks: Sir2 family of NAD+-dependent deacetylases
Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate
H2O2 Accelerates Cellular Senescence by Accumulation of Acetylated p53 via Decrease in the Function of SIRT1 by NAD+ Depletion
Transcription corepressor CtBP is an NAD+-regulated dehydrogenase
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme
Bacterial Na+-translocating ferredoxin:NAD+ oxidoreductase
Pre–B-Cell Colony–Enhancing Factor Regulates NAD+-Dependent Protein Deacetylase Activity and Promotes Vascular Smooth Muscle Cell Maturation
Differences among cell types in NAD+ compartmentalization: A comparison of neurons, astrocytes, and cardiac myocytes
NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells
Poly (ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2α deacetylase …
Autocrine and Paracrine Calcium Signaling by the CD38/NAD+/Cyclic ADP‐Ribose System
Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD+ Redox Homeostasis in Cancer Cells
Altered NADH/NAD+ Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria
Fasting promotes the expression of SIRT1, an NAD+-dependent protein deacetylase, via activation of PPARα in mice
Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE
Poly(ADP‐ribose) The most elaborate metabolite of NAD+
Preventing NAD+ Depletion Protects Neurons against Excitotoxicity: Bioenergetic Effects of Mild Mitochondrial Uncoupling and Caloric Restriction
A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts
Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide
Structural identification of 2′-and 3′-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of β-NAD+-dependent histone/protein …
NAD+‐glycohydrolase acts as an intracellular toxin to enhance the extracellular survival of group A streptococci
NAD+-dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: crystal structure of the adenylation domain and identification of novel inhibitors
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs
NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10
Determination of NAD+ and NADH in a Single Cell under Hydrogen Peroxide Stress by Capillary Electrophoresis
Adenosine Mimetics as Inhibitors of NAD+-Dependent Histone Deacetylases, from Kinase to Sirtuin Inhibition
Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+‐Dependent Histone Deacetylases (Sirtuins)
Regulatory Loop between Redox Sensing of the NADH/NAD+ Ratio by Rex (YdiH) and Oxidation of NADH by NADH Dehydrogenase Ndh in Bacillus subtilis
Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision Repair
NAD+, sirtuins, and cardiovascular disease
A Novel Whole-Cell Biocatalyst with NAD+ Regeneration for Production of Chiral Chemicals
An enzymatic assay for poly (ADP-ribose) polymerase-1 (PARP-1) via the chemical quantitation of NAD+: application to the high-throughput screening of small …
Determining the Extremes of the Cellular NAD(H) Level by Using an Escherichia coli NAD+-Auxotrophic Mutant
Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD+
Pathophysiological relevance of mitochondria in NAD+ metabolism
Telomeric and rDNA Silencing in Saccharomyces cerevisiae Are Dependent on a Nuclear NAD+ Salvage Pathway
Is the Glycolytic Flux in Lactococcus lactisPrimarily Controlled by the Redox Charge?: KINETICS OF NAD+ AND NADH POOLS DETERMINEDIN VIVO BY …
Nicotinamide offers multiple protective mechanisms in stroke as a precursor for NAD+, as a PARP inhibitor and by partial restoration of mitochondrial function
Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals
Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations
Cofactor Regeneration of NAD+ from NADH: Novel Water‐Forming NADH Oxidases
NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity
Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae
A bacterial flavin reductase system reduces chromate to a soluble chromium (III)–NAD+ complex
Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in …
TNF regulates cellular NAD+ metabolism in primary macrophages
Regioselective Reduction of NAD+ Models with [Cp*Rh(bpy)H]+: Structure–Activity Relationships and Mechanistic Aspects in the Formation of the 1,4‐NADH …
Transient Species in the Stepwise Interconversion of NADH and NAD+
Effects of Kynurenine Pathway Inhibition on NAD+ Metabolism and Cell Viability in Human Primary Astrocytes and Neurons
Cofactor Regeneration of both NAD+ from NADH and NADP+ from NADPH:NADH Oxidase from Lactobacillus sanfranciscensis
PropaneMonooxygenase and NAD+-Dependent Secondary AlcoholDehydrogenase in Propane Metabolism by Gordonia sp.StrainTY-5
Ligand‐induced internalization of CD38 results in intracellular Ca2+ mobilization: role of NAD+ transport across cell membranes
Identification of the NAD+-binding fold of glyceraldehyde-3-phosphate dehydrogenase as a novel RNA-binding domain
Structural basis for NADH/NAD+ redox sensing by a Rex family repressor
NAD + -linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer
Vibrio fischeri Genes hvnA andhvnB Encode Secreted NAD+-Glycohydrolases
Crystal structure of NAD+-dependent DNA ligase: modular architecture and functional implications
NAD+: a modulator of immune functions
Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes
NAD+ as a signaling molecule modulating metabolism
Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation
Conserved Enzymatic Production and Biological Effect of O-Acetyl-ADP-ribose by Silent Information Regulator 2-like NAD+-dependent Deacetylases∗
Control of Acetyl-Coenzyme A Synthetase (AcsA) Activity by Acetylation/Deacetylation without NAD+ Involvement in Bacillus subtilis
Kinetic Analysis of Bifidobacterial Metabolism Reveals a Minor Role for Succinic Acid in the Regeneration of NAD+ through Its Growth-Associated Production
A candidate NAD+ transporter in an intracellular bacterial symbiont related to Chlamydiae
NAD+/NADH-Sensitive Quantum Dots: Applications To Probe NAD+-Dependent Enzymes and To Sense the RDX Explosive
NAD+-linked 15-hydroxyprostaglandin dehydrogenase: structure and biological functions
NAD+ activates KNa channels in dorsal root ganglion neurons
Pathway analysis of NAD+ metabolism
Emerging Roles of NAD+ and Its Metabolites in Cell Signaling
Specific and potent inhibition of NAD+-dependent DNA ligase by pyridochromanones
Decreased cADPR and increased NAD+ in the Cd38−/− mouse
Zinc neurotoxicity is dependent on intracellular NAD+ levels and the sirtuin pathway
Discovery of a Ferredoxin:NAD+‐Oxidoreductase (Rnf) in Acetobacterium woodii A Novel Potential Coupling Site in Acetogens
NAD+ Modulates p53 DNA Binding Specificity and Function
Biomimetic NAD+ Models for Tandem Cofactor Regeneration, Horse Liver Alcohol Dehydrogenase Recognition of 1,4‐NADH Derivatives, and Chiral Synthesis
Effects of Kynurenine Pathway Metabolites on Intracellular NAD+ Synthesis and Cell Death in Human Primary Astrocytes and Neurons
The NAD+ Precursor Nicotinamide Governs Neuronal Survival During Oxidative Stress Through Protein Kinase B Coupled to FOXO3a and Mitochondrial …
Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide
The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate
Effects of cytosolic NADH/NAD+ levels on sarcoplasmic reticulum Ca2+ release in permeabilized rat ventricular myocytes
Equilibrium (NAD+/NADH) potential on poly (Neutral Red) modified electrode
Paracrine roles of NAD+ and cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts
The Soluble NAD+-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha H16 Consists of Six Subunits and Can Be Specifically Activated by NADPH
Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling
NAD+ and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration
Photochemical and Radiolytic Production of an Organic Hydride Donor with a RuII Complex Containing an NAD+ Model Ligand
Bioorganometallic chemistry: biocatalytic oxidation reactions with biomimetic NAD+/NADH co-factors and [Cp* Rh (bpy) H]+ for selective organic synthesis
Gold nanoparticles: Catalyst for the oxidation of NADH to NAD+
Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes
The effect of NAPRTase overexpression on the total levels of NAD, the NADH/NAD+ ratio, and the distribution of metabolites in Escherichia coli
Pilot scale production and isolation of recombinant NAD+‐ and NADP+‐specific formate dehydrogenases
Distinct intracellular localization of Gpd1p and Gpd2p, the two yeast isoforms of NAD+-dependent glycerol-3-phosphate dehydrogenase, explains their …
A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ
… riboside and nicotinic acid riboside salvage in fungi and mammals: Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ …
Regulation of hydrogen production by Enterobacter aerogenes by external NADH and NAD+
Eukaryotic NAD+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase
NAD+‐dependent histone deacetylases (sirtuins) as novel therapeutic targets
Regulation of yeast sirtuins by NAD+ metabolism and calorie restriction
Where in the cell is SIRT3? – functional localization of an NAD+-dependent protein deacetylase
Aging, proteotoxicity, mitochondria, glycation, NAD+ and carnosine: possible inter-relationships and resolution of the oxygen paradox
Noncovalent Attachment of NAD+ Cofactor onto Carbon Nanotubes for Preparation of Integrated Dehydrogenase-Based Electrochemical Biosensors
Oxidative stress and NAD+ in ischemic brain injury: current advances and future perspectives
Roles of NAD+/NADH and NADP+/NADPH in cell death
The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation
Electrochemical reduction of NAD+ on a polycrystalline gold electrode
Thiamine Biosynthesis in Saccharomyces cerevisiae Is Regulated by the NAD+-Dependent Histone Deacetylase Hst1
Enhancement of pyruvate productivity in Torulopsis glabrata: increase of NAD+ availability
Reversible, Electrochemical Interconversion of NADH and NAD+ by the Catalytic (Iλ) Subcomplex of Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I)
Esterification of borate with NAD+ and NADH as studied by electrospray ionization mass spectrometry and 11B NMR spectroscopy
Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In Vivo
Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration
Phosphate-responsive signaling pathway is a novel component of NAD+ metabolism in Saccharomyces cerevisiae
Quantitation of NAD+ biosynthesis from the salvage pathway in Saccharomyces cerevisiae
A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP‐ribosyl cyclase, a putative intracellular NAD+ sensor
The NAD+/NADH redox state in astrocytes: Independent control of the NAD+ and NADH content
Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+-dependent phospho-α-glucosidase from Bacillus subtilis
Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal
The role of NAD+ dependent histone deacetylases (sirtuins) in ageing
Connexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport
Regulation of blood flow in activated human brain by cytosolic NADH/NAD+ ratio
NAD+-dependent formate dehydrogenase from plants
Electrocatalytic Detection of NADH and Glycerol by NAD+-Modified Carbon Electrodes
Old enzymes, new tricks: sirtuins are NAD+-dependent de-acylases
Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+
Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies
… coli cells co-expressing pyridine nucleotide transhydrogenase, NADP+-dependent alcohol dehydrogenase and NAD+-dependent formate dehydrogenase
Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases
Sir2 Deacetylases Exhibit Nucleophilic Participation of Acetyl-Lysine in NAD+ Cleavage
… of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ …
Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis
Nicotinamide Attenuates Focal Ischemic Brain Injury in Rats: With Special Reference to Changes in Nicotinamide and NAD+ Levels in Ischemic Core and Penumbra
Determining a novel NAD+-dependent amine dehydrogenase with a broad substrate range from Streptomyces virginiae IFO 12827: purification and characterization
Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status
Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor
Assimilation of NAD+ precursors in Candida glabrata
The time of metabolism: NAD+, SIRT1, and the circadian clock
Implication of Poly(ADP‐Ribose) Polymerase (PARP) in Neurodegeneration and Brain Energy Metabolism: Decreases in Mouse Brain NAD+ and ATP Caused by …
Nicotinamidase modulation of NAD+ biosynthesis and nicotinamide levels separately affect reproductive development and cell survival in C. elegans
Probing the Active Site of an O2‐Tolerant NAD+‐Reducing [NiFe]‐Hydrogenase from Ralstonia eutropha H16 by In Situ EPR and FTIR Spectroscopy
Inhibitors to understand molecular mechanisms of NAD+-dependent deacetylases (sirtuins)
Reversible Redox of NADH and NAD+ at a Hybrid Lipid Bilayer Membrane Using Ubiquinone
Mitochondrial NAD+‐linked State 3 respiration and complex‐I activity are compromised in the cerebral cortex of 3‐nitropropionic acid‐induced rat model of …
Reactivity of Poly(anilineboronic acid) with NAD+ and NADH
Interleukin-10 Modifies the Effects of Interleukin-1β and Tumor Necrosis Factor-α on the Activity and Expression of Prostaglandin H Synthase-2 and the NAD+ …
Mechanism of Hydride Donor Generation Using a Ru(II) Complex Containing an NAD+ Model Ligand: Pulse and Steady-State Radiolysis Studies
Cyanobacterial-Type, Heteropentameric, NAD+-Reducing NiFe Hydrogenase in the Purple Sulfur Photosynthetic Bacterium Thiocapsa roseopersicina
Effects of salinities on the gene expression of a (NAD+)-dependent glycerol-3-phosphate dehydrogenase in Dunaliella salina
Mycobacterium tuberculosis NAD+-dependent DNA ligase is selectively inhibited by glycosylamines compared with human DNA ligase I
SIRT1 markedly extends replicative lifespan if the NAD+ salvage pathway is enhanced
Evaluating Enzyme Cascades for Methanol/Air Biofuel Cells Based on NAD+‐Dependent Enzymes
Resveratrol inhibited Tat-induced HIV-1 LTR transactivation via NAD+-dependent SIRT1 activity
Levels of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-α
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD+ biosynthesis
Crystal structure of Thermotoga maritima α-glucosidase AglA defines a new clan of NAD+-dependent glycosidases
High Yields of 2,3-Butanediol and Mannitol in Lactococcus lactis through Engineering of NAD+ Cofactor Recycling
Catalytic Properties of the Isolated Diaphorase Fragment of the NAD+-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha
Direct electrochemical regeneration of NADH from NAD+ using cholesterol-modified gold amalgam electrode
Computational prediction and experimental verification of the gene encoding the NAD+/NADP+-dependent succinate semialdehyde dehydrogenase in Escherichia …
Catalysis of regioselective reduction of NAD+ by ruthenium(II) arene complexes under biologically relevant conditions
Nrt1 and Tna1-Independent Export of NAD+ Precursor Vitamins Promotes NAD+ Homeostasis and Allows Engineering of Vitamin …
Characterization of Streptococcus pyogenes β-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesis
Hydrolase regulates NAD+ metabolites and modulates cellular redox
Extracellular NAD+ induces a rise in [Ca2+] i in activated human monocytes via engagement of P2Y1 and P2Y11 receptors
Inhibitors of NAD+ dependent histone deacetylases (sirtuins)
Synthesizing and Salvaging NAD+: Lessons Learned from Chlamydomonas reinhardtii
Novel 3-Arylideneindolin-2-ones as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)
Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases
Identification of selective inhibitors of NAD+-dependent deacetylases using phenotypic screens in yeast
NAD+-dependent DNA ligase encoded by a eukaryotic virus
In situ NAD+ regeneration using 2, 2′-azinobis (3-ethylbenzothiazoline-6-sulfonate) as an electron transfer mediator
Evidence for an intracellular ADP-ribosyl cyclase/NAD+-glycohydrolase in brain from CD38-deficient mice
Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases
A Substrate in Pieces: Allosteric Activation of Glycerol 3-Phosphate Dehydrogenase (NAD+) by Phosphite Dianion
… for flow injection analysis based on a screen-printed carbon electrode containing Meldola’s Blue-Reinecke salt, coated with lactate dehydrogenase and NAD+
Regulation of active site coupling in glutamine-dependent NAD+ synthetase
Local Administration of the Poly(ADP-Ribose) Polymerase Inhibitor INO-1001 Prevents NAD+ Depletion and Improves Water Maze Performance after Traumatic Brain …
NAD+ auxotrophy is bacteriocidal for the tubercle bacilli
Functional analysis of structural genes for NAD+‐dependent formate dehydrogenase in Saccharomyces cerevisiae
Molecular Dynamics Simulations of Ground and Transition States for the Hydride Transfer from Formate to NAD+ in the Active Site of Formate Dehydrogenase
Structure of the adenylation domain of an NAD+-dependent DNA ligase
Promotion of cellular NAD+ anabolism: Therapeutic potential for oxidative stress in ageing and alzheimer’s disease
Reversible cyclic voltammetry of the NADH/NAD+ redox system on hybrid poly (luminol)/FAD film modified electrodes
Serum or target deprivation‐induced neuronal death causes oxidative neuronal accumulation of Zn2+ and loss of NAD+
Free [NADH]/[NAD+] regulates sirtuin expression
NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-β-D-glucosides
The Hydrogenase Subcomplex of the NAD+‐Reducing [NiFe] Hydrogenase from Ralstonia eutropha – Insights into Catalysis and Redox Interconversions
Biochemical characterization of Plasmodium falciparum Sir2, a NAD+-dependent deacetylase
Optical and Electrochemical Detection of NADH and of NAD+‐Dependent Biocatalyzed Processes by the Catalytic Deposition of Copper on Gold Nanoparticles
Mouse lacking NAD+-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle
The NAD+-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication
Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs
SIR2: the biochemical mechanism of NAD+-dependent protein deacetylation and ADP-ribosyl enzyme intermediates
Crystal Structure of a Ternary Complex of Tritrichomonas foetus Inosine 5′-Monophosphate Dehydrogenase: NAD+ Orients the Active Site Loop for Catalysis,
An integrated NAD+-dependent enzyme-functionalized field-effect transistor (ENFET) system: development of a lactate biosensor
A Novel NAD+-dependent aldehyde dehydrogenase encoded by the puuC gene of Klebsiella pneumoniae DSM 2026 that utilizes 3-hydroxypropionaldehyde as a …
New biotechnological perspectives of a NADH oxidase variant from Thermus thermophilus HB27 as NAD+-recycling enzyme
Glutamine-dependent NAD+ synthetase: how a two-domain, three-substrate enzyme avoids waste
… composites of conducting poly (p-ABSA) and flavins (FAD, FMN, RF) films and their use as electrochemical sensors: A new potent electroanalysis of NADH and NAD+
Vitamins and aging: pathways to NAD+ synthesis
Peroxisome-proliferator regulates key enzymes of the tryptophan-NAD+ pathway
Ligation reaction specificities of an NAD+-dependent DNA ligase from the hyperthermophile Aquifex aeolicus
Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+
Liposomal NAD+ prevents diminished O2consumption by immunostimulated Caco-2 cells
Biofuel cell anode: NAD+/glucose dehydrogenase-coimmobilized ketjenblack electrode
Evaluation of NAD+-Dependent DNA Ligase of Mycobacteria as a Potential Target for Antibiotics
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies
Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX
Deletion or Overexpression of Mitochondrial NAD+ Carriers in Saccharomyces cerevisiae Alters Cellular NAD and ATP Contents and Affects Mitochondrial …
The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+-dependent deacetylase and ADP-ribosyltransferase
… of horse liver alcohol dehydrogenase (HLADH): results of molecular dynamics simulations of HLADH-NAD+-PhCH2OH, HLADH-NAD+-PhCH2O-, and HLADH-NADH …
A novel ISFET-based NAD+-dependent enzyme sensor for lactate
The Effect of Antioxidant Supplementation on Fatigue during Exercise: Potential Role for NAD+(H)
NAD+ depletion or PAR polymer formation: which plays the role of executioner in ischaemic cell death?
Purification and characterization of a NAD+-dependent sorbitol dehydrogenase from Japanese pear fruit
The general anesthetic sevoflurane affects the expression of clock gene mPer2 accompanying the change of NAD+ level in the suprachiasmatic nucleus of mice
Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicumNMN adenylyltransferase …
Crystal Structure of meso-2,3-Butanediol Dehydrogenase in a Complex with NAD+ and Inhibitor Mercaptoethanol at 1.7 A Resolution for Understanding of Chiral …
Acute ammonia intoxication induces an NMDA receptor‐mediated increase in poly(ADP‐ribose) polymerase level and NAD+ metabolism in nuclei of rat brain cells
Determination of formal potential of NADH/NAD+ redox couple and catalytic oxidation of NADH using poly (phenosafranin)-modified carbon electrodes
Mutation in the HPGD gene encoding NAD+ dependent 15-hydroxyprostaglandin dehydrogenase underlies isolated congenital nail clubbing (ICNC)
NADH/NAD+ interaction with NADH: ubiquinone oxidoreductase (complex I)
Poly (neutral red) as a NAD+ reduction catalyst and a NADH oxidation catalyst: Towards the development of a rechargeable biobattery
NAD+‐dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: Novel structure‐function relationship and identification of a specific inhibitor
Mechanism of action and NAD+-binding mode revealed by the crystal structure of l-histidinol dehydrogenase
Selective Complexation of N‐Alkylpyridinium Salts: Binding of NAD+ in Water
NADP+ and NAD+ binding to the dual coenzyme specific enzyme Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: different interdomain hinge …
A chemical synthesis of nicotinamide adenine dinucleotide (NAD+)
Selective release and function of one of the two FMN groups in the cytoplasmic NAD+‐reducing [NiFe]‐hydrogenase from Ralstonia eutropha
5′-Nucleotidases and their new roles in NAD+ and phosphate metabolism
Benzo [a] pyrene-induced necrosis in the HepG2 cells via PARP-1 activation and NAD+ depletion
Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition
Mitochondrial dysfunction, proteotoxicity, and aging: causes or effects, and the possible impact of NAD+-controlled protein glycation
Allosteric motions in structures of yeast NAD+-specific isocitrate dehydrogenase
… of complex I (NADH: ubiquinone oxidoreductase) from bovine heart mitochondria: insights into the mechanisms of NADH oxidation and NAD+ reduction from protein …
Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells
A second NAD+-dependent DNA ligase (LigB) in Escherichia coli
Systematic evaluation of the dihydrogen-oxidising and NAD+-reducing soluble [NiFe]-hydrogenase from Ralstonia eutropha H16 as a cofactor regeneration catalyst
The Human NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Gene Promoter Is Controlled by Ets and Activating Protein-1 Transcription Factors and …
Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide
A kinetic study of NAD+ reduction on a ruthenium modified glassy carbon electrode
Identification and functional characterization of a novel, tissue-specific NAD+-dependent isocitrate dehydrogenase β subunit isoform
Inhibition of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents
Photochemical Stereospecific Hydrogenation of a Ru Complex with an NAD+/NADH-Type Ligand
ATP‐ and NAD+‐dependent DNA ligases share an essential function in the halophilic archaeon Haloferax volcanii
Thermotoga maritima AglA, an extremely thermostable NAD+-, Mn2+-, and thiol-dependent α-glucosidase
Logic of a mammalian metabolic cycle: an oscillated NAD+/NADH redox signaling regulates coordinated histone expression and S-phase progression
Extracellular NAD+ regulates intracellular free calcium concentration in human monocytes
Plasmodium falciparum Sir2 is an NAD+-Dependent Deacetylase and an Acetyllysine-Dependent and Acetyllysine-Independent NAD+ Glycohydrolase
Kinetic competence of the cADP-ribose–CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling
Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus
Flow-through 3D biofuel cell anode for NAD+-dependent enzymes
Quinolinate phosphoribosyl transferase, a key enzyme in de novo NAD+ synthesis, suppresses spontaneous cell death by inhibiting overproduction of active …
Substituting Nε-thioacetyl-lysine for Nε-acetyl-lysine in Peptide Substrates as a General Approach to Inhibiting Human NAD+-dependent Protein Deacetylases
Metabolism of 4-Hydroxy-trans-2-nonenal by Central Nervous System Mitochondria Is Dependent on Age and NAD+ Availability
High-Affinity Transporters for NAD+ Precursors in Candida glabrata Are Regulated by Hst1 and Induced in Response to Niacin Limitation
Characterization of the NAD+ binding site of Candida boidinii formate dehydrogenase by affinity labelling and site‐directed mutagenesis
Amperometric Ethanol Biosensors Based on Chitosan‐NAD+‐Alcohol Dehydrogenase Films
Artificial redox coenzymes: biomimetic analogues of NAD+
Functional domains of an NAD+-dependent DNA ligase
The NAD+ precursors, nicotinic acid and nicotinamide upregulate glyceraldehyde-3-phosphate dehydrogenase and glucose-6-phosphate dehydrogenase mRNA in …
Interactive Adsorption Behavior of NAD+ at a Gold Electrode Surface
Involvement of P2X receptors in the NAD+-induced rise in [Ca2+]i in human monocytes
A single‐point mutation enables lactate dehydrogenase from Bacillus subtilis to utilize NAD+ and NADP+ as cofactor
NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine‐1‐phosphate levels accompanying G1 …
Implicating PARP and NAD+ depletion in type I diabetes
Bi-enzyme biosensor based on NAD+-and glutathione-dependent recombinant formaldehyde dehydrogenase and diaphorase for formaldehyde assay
Crystal structures of the short-chain flavin reductase HpaC from Sulfolobus tokodaii strain 7 in its three states: NAD (P)+-free, NAD+-bound, and NADP+-bound
Tryptophan–NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation
NAD+ ameliorates inflammation-induced epithelial barrier dysfunction in cultured enterocytes and mouse ileal mucosa
NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Regulates Levels of Bioactive Lipids in Non–Small Cell Lung Cancer
Diastereocontrolled Electrophilic Fluorinations of 2-Deoxyribonolactone: Syntheses of All Corresponding 2-Deoxy-2-fluorolactones and 2′-Deoxy-2′-fluoro-NAD+s
… evaluation of the reaction rate between methyl viologen mediator and diaphorase enzyme for the electrocatalytic reduction of NAD+ and digital simulation for its …
NAD+‐Dependent DNA Ligase: A novel target waiting for the right inhibitor
Liposomal atp or NAD+ protects human endothelial cells from energy failure in a cell culture model of sepsis.
Purification and physical and kinetic characterization of an NAD+‐dependent malate dehydrogenase from leaves of pineapple (Ananas comosus)
Conformations of nicotinamide adenine dinucleotide (NAD+) in various environments
Primary Kinetic Isotope Effects on Hydride Transfer from 1,3-Dimethyl-2-phenylbenzimidazoline to NAD+ Analogues
Cloning and characterization of a NAD+-dependent glycerol-3-phosphate dehydrogenase gene from Candida glycerinogenes, an industrial glycerol producer
Quantitative assays for characterization of the Sir2 family of NAD+-dependent deacetylases
Coupling of NAD+ Biosynthesis and Nicotinamide Ribosyl Transport: Characterization of NadR Ribonucleotide Kinase Mutants of Haemophilus influenzae
Depletion of intracellular NAD+ and ATP levels during ricin-induced apoptosis through the specific ribosomal inactivation results in the cytolysis of U 937 cells
The gdhB Gene of Pseudomonas aeruginosaEncodes an Arginine-Inducible NAD+-Dependent Glutamate Dehydrogenase Which Is Subject to Allosteric Regulation
Saccharomyces cerevisiae QNS1 codes for NAD+ synthetase that is functionally conserved in mammals
Steady-state kinetic mechanism of the NADP+-and NAD+-dependent reactions catalysed by betaine aldehyde dehydrogenase from Pseudomonas aeruginosa
The action of quercetin on the mitochondrial NADH to NAD+ ratio in the isolated perfused rat liver
Homologous binding sites in yeast isocitrate dehydrogenase for cofactor (NAD+) and allosteric activator (AMP)
Thiazolidinediones as a novel class of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
Specificity of Streptococcus pyogenes NAD+ glycohydrolase in cytolysin‐mediated translocation
Functional Analysis by Site-Directed Mutagenesis of the NAD+-Reducing Hydrogenase from Ralstonia eutropha
Deprotonation of the Horse Liver Alcohol Dehydrogenase−NAD+ Complex Controls Formation of the Ternary Complexes
Direct detection of formaldehyde in air by a novel NAD+-and glutathione-independent formaldehyde dehydrogenase-based biosensor
High-Affinity Inhibitors of Human NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships
Variation in Streptococcus pyogenes NAD+ Glycohydrolase Is Associated with Tissue Tropism
Converting NADH to NAD+ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging
Induction of NAD+-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells
Molecular dynamics simulations of NAD+-induced domain closure in horse liver alcohol dehydrogenase
A Dual Function α-Dioxygenase-Peroxidase and NAD+Oxidoreductase Active Enzyme from Germinating Pea Rationalizing α-Oxidation of Fatty Acids in Plants,
Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+
Copper Ions Inhibit S-Adenosylhomocysteine Hydrolase by Causing Dissociation of NAD+ Cofactor
Involvement of matrix NADP turnover in the oxidation of NAD+‐linked substrates by pea leaf mitochondria
Biochemical characterization of isocitrate dehydrogenase from Methylococcus capsulatus reveals a unique NAD+-dependent homotetrameric enzyme
A disubstituted NAD+ analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase
NAD+-metabolizing ecto-enzymes shape tumor–host interactions: The chronic lymphocytic leukemia model
Structural basis for stereo‐specific catalysis in NAD+‐dependent (R)‐2‐hydroxyglutarate dehydrogenase from Acidaminococcus fermentans
… hepatic S-adenosylmethionine and S-adenosylhomocysteine levels in the isolated perfused rat liver through changes in the redox state of the NADH/NAD+ …
… in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274→ Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and …
Comparative study of the surface enhanced near infrared Raman spectra of adenine and NAD+ on a gold electrode
Unifying mechanism for Aplysia ADP-ribosyl cyclase and CD38/NAD+ glycohydrolases
Coulometric determination of NAD+ and NADH in normal and cancer cells using LDH, RVC and a polymer mediator
Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD+ catabolizing enzyme
Characterization of a thermally stable and organic solvent–adaptative NAD+‐dependent formate dehydrogenase from Bacillus sp. F1
A combined experimental and theoretical study of the pH‐dependent binding mode of NAD+ by water‐soluble molecular clips
Experimental and Theoretical Electron Density Studies in Large Molecules: NAD+, β-Nicotinamide Adenine Dinucleotide
Structural basis of Streptococcus pyogenes immunity to its NAD+ glycohydrolase toxin
Water Maze Performance in Young Male Long-Evans Rats Is Inversely Affected by Dietary Intakes of Niacin and May Be Linked to Levels of the NAD+ Metabolite …
Regulation of NAD+-dependent isocitrate dehydrogenase in the citrate producing yeast yarrowia lipolytica
Dimethyl sulfoxide at 2.5% (v/v) alters the structural cooperativity and unfolding mechanism of dimeric bacterial NAD+ synthetase
Polyubiquitylation of PARP‐1 through ubiquitin K48 is modulated by activated DNA, NAD+, and dipeptides
Molecular Dynamics Simulations of NAD+ in Solution
Identification and characterization of an inhibitor specific to bacterial NAD+‐dependent DNA ligases
The Tightness Contribution to the Brønsted α for Hydride Transfer between NAD+ Analogues
… of oxidized nicotinamide adenine dinucleotide (NAD+) analogues using a high-pressure-liquid-chromatography-based NAD+-glycohydrolase assay and comparison …
Biochemical and molecular characterization of the NAD+-dependent isocitrate dehydrogenase from the chemolithotroph Acidithiobacillus thiooxidans
Increased activity of glucose dehydrogenase co-immobilized with a redox mediator in a bioreactor with electrochemical NAD+ regeneration
The catalytic mechanism of Drosophila alcohol dehydrogenase: Evidence for a proton relay modulated by the coupled ionization of the active site Lysine/Tyrosine pair and a …
Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis
Photoinduced four-and six-electron reduction of mononuclear ruthenium complexes having NAD+ analogous ligands
Differences of pH-Dependent Mechanisms on Generation of Hydride Donors using Ru(II) Complexes Containing Geometric Isomers of NAD+ Model Ligands: NMR …
Improvement of Coenzyme Q10 Production by Increasing the NADH/NAD+ Ratio in Agrobacterium tumefaciens
Muscle type-specific responses to NAD+ salvage biosynthesis promote muscle function in Caenorhabditis elegans
Structure–function analysis of the yeast NAD+-dependent tRNA 2′-phosphotransferase Tpt1
The structure of the 1L-myo-inositol-1-phosphate synthase-NAD+-2-deoxy-D-glucitol 6-(E)-vinylhomophosphonate complex demands a revision of the …
Biochemical characterisation of LigN, an NAD+-dependent DNA ligase from the halophilic euryarchaeon Haloferax volcanii that displays maximal in vitro …
Dysregulation of Myeloid‐specific Transcription Factors in Congenital Neutropenia: Rescue by NAMPT/NAD+/SIRT1
Structure and quantum chemical analysis of NAD+‐dependent isocitrate dehydrogenase: Hydride transfer and co‐factor specificity
Synthesis and biological activity of splitomicin analogs targeted at human NAD+-dependent histone deacetylases (sirtuins)
Discovery of bacterial NAD+-dependent DNA ligase inhibitors: Optimization of antibacterial activity
Optimization of the mediated electrocatalytic reduction of NAD+ by cyclic voltammetry and construction of electrochemically driven enzyme bioreactor
Insulin-stimulated NADH/NAD+ redox state increases NAD (P) H oxidase activity in cultured rat vascular smooth muscle cells
Recent Advances in Physiological and Pathological Significance of tryptophan-NAD+Metabolites: lessons from insulin-producing pancreatic ß-Cells
Thymidine production by overexpressing NAD+ kinase in an Escherichia coli recombinant strain
Pd (core)–Au (shell) nanoparticles catalyzed conversion of NADH to NAD+ by UV–vis spectroscopy—a kinetic analysis
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain
Atomic resolution crystal structure of NAD+ dependent formate dehydrogenase from bacterium Moraxella sp. C-1
NH3-dependent NAD+ synthetase from Bacillus subtilis at 1 Å resolution
NAD+ and NADH in Neuronal Death
Amperometric detection of d-sorbitol with NAD+-d-sorbitol dehydrogenase modified carbon paste electrode
Characterization of mimivirus NAD+-dependent DNA ligase
Structures of NAD+-and NADH-bound 1-l-myo-inositol 1-phosphate synthase
Cofactor binding modulates the conformational stabilities and unfolding patterns of NAD+-dependent DNA ligases from Escherichia coli and Thermus …
Isocitrate binding at two functionally distinct sites in yeast NAD+-specific isocitrate dehydrogenase
Gene expression of NAD+-dependent sorbitol dehydrogenase and NADP+-dependent sorbitol-6-phosphate dehydrogenase during development of loquat (Eriobotrya …
The hidden life of NAD+-consuming ectoenzymes in the endocrine system
Effects of 2-deoxyglucose and dehydroepiandrosterone on intracellular NAD+ level, SIRT1 activity and replicative lifespan of human Hs68 cells
Adenylation-dependent conformation and unfolding pathways of the NAD+-dependent DNA ligase from the thermophile Thermus scotoductus
Glutamate-115 renders specificity of human 11β-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+
An NAD+-dependent glutamate dehydrogenase cloned from the ruminal ciliate protozoan, Entodinium caudatum
Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation
Structure of D-lactate dehydrogenase from Aquifex aeolicus complexed with NAD+ and lactic acid (or pyruvate)
A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2in chromosome …
Prediction of the active-site structure and NAD+ binding in SQD1, a protein essential for sulfolipid biosynthesis in Arabidopsis
Isolation of a GPD gene from Debaryomyces hansenii encoding a glycerol 3‐phosphate dehydrogenase (NAD+)
Inhibition of the Kynurenine-NAD+ Pathway Leads to Energy Failure and Exacerbates Apoptosis in Pneumococcal Meningitis
SERS Investigation of NAD+ Adsorbed on a Silver Electrode
Hydride-exchange reactions between NADH and NAD+ model compounds under non-steady-state conditions. Apparent and real kinetic isotope effects
Extracellular NAD+ metabolism modulates osteoclastogenesis
Drug Selectivity Is Determined by Coupling Across the NAD+ Site of IMP Dehydrogenase
NADH oxidation and NAD+ reduction catalysed by tightly coupled inside‐out vesicles from Paracoccus denitrificans
Experimental cancer therapy using restoration of NAD+-linked 15-hydroxyprostaglandin dehydrogenase expression15-PGDH–Mediated Cancer Therapy
Preparation of axially chiral quinolinium salts related to NAD+ models: new investigations of these biomimetic models as ‘chiral amide-transferring agents’
Overproduction of NAD+ and 5′-inosine monophosphate in the presence of 10 μM Mn 2+ by a mutant of Corynebacterium ammoniagenes with thermosensitive …
NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae
NAD+-dependent post-translational modification of Escherichia coli glyceraldehyde-3-phosphate dehydrogenase
A Shared Binding Site for NAD+ and Coenzyme A in an Acetaldehyde Dehydrogenase Involved in Bacterial Degradation of Aromatic Compounds
The Antarctic Psychrobacter sp. TAD1 has two cold-active glutamate dehydrogenases with different cofactor specificities. Characterisation of the NAD+-dependent …
Therapeutic potential of NAD+ for neurological diseases
Expression of NAD+-dependent formate dehydrogenase in Enterobacter aerogenes and its involvement in anaerobic metabolism and H2 production
Alteration of the NAD+/NADH ratio in CHO cells by stable transfection with human cytosolic glycerol-3-phosphate dehydrogenase: resistance to oxidative …
Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis
4-Pyridone-3-carboxamide-1-β-d-ribonucleoside Triphosphate (4PyTP), a Novel NAD+ Metabolite Accumulating in Erythrocytes of Uremic Children: A Biomarker for a Toxic …
Genes malh and pagl of Clostridium acetobutylicum ATCC 824 encode NAD+-and Mn2+-dependent phospho-α-glucosidase (s)
Kinetic study of the enzymatic cycling reaction conducted with 3α-hydroxysteroid dehydrogenase in the presence of excessive thio-NAD+ and NADH
Extracellular NAD+ induces calcium signaling and apoptosis in human osteoblastic cells
Small-angle X-ray scattering study of a Rex family repressor: conformational response to NADH and NAD+ binding in solution
Identification of residues important for NAD+ binding by the Thermotoga maritima α-glucosidase AglA, a member of glycoside hydrolase family 4
Survey of normal appearing mouse strain which lacks enzyme and NAD+-linked glycerol phosphate dehydrogenase: Normal pancreatic beta cell function, but …
Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Hydride Reduction of NAD+ Analogues by Isopropyl Alcohol: Kinetics, Deuterium Isotope Effects and Mechanism
NAD+ Treatment Induces Delayed Autophagy in Neuro2a Cells Partially by Increasing Oxidative Stress
Adenosine binding sites at S-adenosylhomocysteine hydrolase are controlled by the NAD+/NADH ratio of the enzyme
NAD+-dependent (S)-specific secondary alcohol dehydrogenase involved in stereoinversion of 3-pentyn-2-ol catalyzed by Nocardia fusca AKU 2123
Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Determination of lactose and D-galactose using thio-NAD+ instead of NAD+
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD+ synthetase
The linear dependence of log (kcat/Km) for reduction of NAD+ by PhCH2OH on the distance between reactants when catalyzed by horse liver alcohol dehydrogenase …
Novel Chemo‐Enzymatic Mimic of Hydrogen Peroxide‐Forming NAD(P)H Oxidase for Efficient Regeneration of NAD+ and NADP+
… ) hydroborato zinc complexes: Unexpected example of zinc hydride formation in a protic solvent and its relevance towards hydrogen transfer to NAD+ mimics by tris …
Allosteric Inhibition of NAD+-Specific Isocitrate Dehydrogenase by a Mitochondrial mRNA
Structure of 2‐deoxy‐scyllo‐inosose synthase, a key enzyme in the biosynthesis of 2‐deoxystreptamine‐containing aminoglycoside antibiotics, in complex with a mechanism …
NAD+‐dependent DNA ligases of Mycobacterium tuberculosis and Streptomyces coelicolor
NAD+ Utilization in Pasteurellaceae: Simplification of a Complex Pathway
Isolation and characterization of a benzoylformate decarboxylase and a NAD+/NADP+-dependent benzaldehyde dehydrogenase involved in D-phenylglycine …
Bovine NAD+-Dependent Isocitrate Dehydrogenase: Alternative Splicing and Tissue-Dependent Expression of Subunit 1
Selective aerobic oxidation of sulfides to sulfoxides catalyzed by coenzyme NAD+ models
The Role of NAD+ Depletion in the Mechanism of Sulfur Mustard–Induced Metabolic Injury
NAD+ and NADH in ischemic brain injury
Picomolar Detection of Hydrogen Peroxide at Glassy Carbon Electrode Modified with NAD+ and Single Walled Carbon Nanotubes
Electrocatalytic reduction of NAD+ at glassy carbon electrode modified with single-walled carbon nanotubes and Ru(III) complexes
Regiospecific Hydride Transfer from cis‐[Ru(bpy)2(CO)(CHO)]+ to NAD+ Model Compounds: A Model for Enzymatic Reactions by Aldehyde Dehydrogenases
Effect of NAD+-dependent isocitrate dehydrogenase gene (IDH1, IDH2) disruption of sake yeast on organic acid composition in sake mash
Electrocatalytic properties of NDGA and NDGA/FAD hybrid film modified electrodes for NADH/NAD+ redox reaction
Characterization and possible redox regulation of the purified calmodulin‐dependent NAD+ kinase from Lycopersicon pimpinellifolium
Factors Controlling the Mechanism of NAD+ Non-Redox Reactions
Toward the virtual screening of potential drugs in the homology modeled NAD+ dependent DNA ligase from Mycobacterium tuberculosis
Tween-20 Activates and Solubilizes the Mitochondrial Membrane-bound, Calmodulin Dependent NAD+ Kinase of Avena sativa L.
NAD+-induced vasotoxicity in the pericyte-containing microvasculature of the rat retina: effect of diabetes
Genomic structure and transcriptional regulation of the human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene
Oxidation of butane to butanol coupled to electrochemical redox reaction of NAD+/NADH
Extracellular NAD+: a novel autocrine/paracrine signal in osteoblast physiology
Photocatalytic oxidation of primary and secondary benzyl alcohol catalyzed by two coenzyme NAD+ models
Engineered Glycolytic Glyceraldehyde-3-Phosphate Dehydrogenase Binds theAntiConformation of NAD+ Nicotinamide but Does Not Experience A-Specific Hydride …
Improving the Purification of NAD+‐Dependent Formate Dehydrogenase from Candida methylica
The base exchange reaction of NAD+ glycohydrolase: identification of novel heterocyclic alternative substrates
Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD+ and triclosan
Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD+ Concentration in Human Primary Astrocytes
Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH
Cloning and expression of a NAD+-dependent xylitol dehydrogenase gene (xdhA) of Aspergillus oryzae
Structure-guided mutational analysis of the nucleotidyltransferase domain of Escherichia coli NAD+-dependent DNA ligase (LigA)
Molecular cloning and functional expression of bovine spleen ecto-NAD+ glycohydrolase: structural identity with human CD38
Electrochemical and Photochemical Behavior of a Ruthenium(II) Complex Bearing Two Redox Sites as a Model for the NAD+/NADH Redox Couple
CD38 expression and NAD+‐induced intracellular Ca2+ mobilization in isolated retinal Müller cells
Increased synthesis and decreased stability of mitochondrial translation products in yeast as a result of loss of mitochondrial (NAD+)‐dependent isocitrate …
Significant Enhancement of Electron Transfer Reduction of NAD+ Analogues by Complexation with Scandium Ion and the Detection of the Radical Intermediate …
Can the combination of electrochemical regeneration of NAD+, selectivity of L‐α‐amino‐acid dehydrogenase, and reductive amination of α‐keto‐acid be applied to …
Structure of D-3-hydroxybutyrate dehydrogenase prepared in the presence of the substrate D-3-hydroxybutyrate and NAD+
Pre–B-cell Colony-Enhancing Factor Regulates Vascular Smooth Muscle Maturation Through a NAD+-Dependent Mechanism: Recognition of a New Mechanism for …
Structural determinants of discrimination of NAD+ from NADH in yeast mitochondrial NADH kinase Pos5
Stereospecificity of hydrogen transfer by the NAD+-linked alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123
Resveratrol increases intracellular NAD+ levels through up regulation of the NAD+ synthetic enzyme nicotinamide mononucleotide adenylyltransferase
Membrane permeability of redox active metal chelators: an important element in reducing hydroxyl radical induced NAD+ depletion in neuronal cells
Kinetics of the Hydride Reduction of an NAD+ Analogue by Isopropyl Alcohol in Aqueous and Acetonitrile Solutions: Solvent Effects, Deuterium Isotope Effects, and …
Crystal structures of complexes of NAD+-dependent formate dehydrogenase from methylotrophic bacterium Pseudomonas sp. 101 with formate
Purification and characterisation of NAD+-dependent xylitol dehydrogenase from Fusarium oxysporum
Effects of Deletion and Site-Directed Mutations on Ligation Steps of NAD+-Dependent DNA Ligase: A Biochemical Analysis of BRCA1 C-Terminal Domain
Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes
Mechanism of the catalysis by Alcaligenes eutrophus H16 hydrogenase of direct electrochemical reduction of NAD+
Trypanosoma brucei UDP-galactose-4′-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-α-D-galactose
Roles of His205, His296, His303 and Asp259 in catalysis by NAD+‐specific D‐lactate dehydrogenase
Mutational analyses of the thermostable NAD+-dependent DNA ligase from Thermus filiformis
NAD+ Availability and Proteotoxicity
Molecular Cloning and Characterization of NAD+‐Dependent Xylitol Dehydrogenase from Candida tropicalis ATCC 20913
The NAD+ metabolism of Leishmania, notably the enzyme nicotinamidase involved in NAD+ salvage, offers prospects for development of anti‐parasite …
Kinetic and Physiological Effects of Alterations in Homologous Isocitrate-Binding Sites of Yeast NAD+-Specific Isocitrate Dehydrogenase
In Search for New Antipsoriatic Agents: NAD+ Topical Composition
Characterization of a mutation in the IDH-II subunit of the NAD+-dependent isocitrate dehydrogenase from Arabidopsis thaliana
Oxovanadium (IV) complexes of phosphates of biological relevance: NAD+, NADP+ and thiamine mono-and diphosphate
Sir2-Related Protein 1 from Leishmania amazonensis is a glycosylated NAD+-dependent deacetylase
The effect of iron limitation on glycerol production and expression of the isogenes for NAD+-dependent glycerol 3-phosphate dehydrogenase in …
Novel nicotinamide adenine dinucleotide analogues as selective inhibitors of NAD+-dependent enzymes
Characterization of azido-NAD+ to assess its potential as a two-dimensional infrared probe of enzyme dynamics
Subunit interactions of yeast NAD+-specific isocitrate dehydrogenase
Nicotinamide 2-Fluoroadenine Dinucleotide Unmasks the NAD+ Glycohydrolase Activity of Aplysia californica Adenosine 5′-Diphosphate Ribosyl Cyclase
Reinterpretation of the Brønsted α for Redox Reactions Based on the Effect of Substituents on Hydride Transfer Reaction Rates between NAD+ Analogues
Proton-Induced Dynamic Equilibrium between Cyclometalated Ruthenium rNHC (Remote N-Heterocyclic Carbene) Tautomers with an NAD+/NADH Function
Sorbitol-and other sugar-induced expressions of the NAD+-dependent sorbitol dehydrogenase gene in Japanese pear fruit
Insulin increases NADH/NAD+ redox state, which stimulates guanylate cyclase in vascular smooth muscle
Catalytic Oxidoreduction of Pyruvate/Lactate and Acetaldehyde/EthanolCoupled to Electrochemical Oxidoreduction of NAD+/NADH
Bias from H2 Cleavage to Production and Coordination Changes at the Ni−Fe Active Site in the NAD+-Reducing Hydrogenase from Ralstonia eutropha
Synthesis, in silico screening and bioevaluation of dispiro-cycloalkanones as antitubercular and mycobacterial NAD+-dependent DNA ligase inhibitors
… Reduction of a Ruthenium Complex Bearing an N, N‐Bis [(benzo [g][1, 5] naphthyridin‐2‐yl) methyl] propane‐2‐amine Ligand as an NAD+/NADH‐Type Redox Site
Allosteric activation of pyruvate kinase via NAD+ in rat liver cells
NAD+ treatment decreases tumor cell survival by inducing oxidative stress
Transformation products of extracellular NAD+ in the rat liver: kinetics of formation and metabolic action
Polymer-Assisted Solution-Phase Synthesis of 2′-Amido-2′-deoxyadenosine Derivatives Targeted at the NAD+-Binding Sites of Parasite Enzymes
In situ Raman spectra of an NAD+‐modified silver electrode at various potentials
Efficient repeated use of alcohol dehydrogenase with NAD+ regeneration in an aqueous-organic two-phase system
Poly(ADP‐Ribose)‐Polymerase‐Catalyzed Hydrolysis of NAD+: QM/MM Simulation of the Enzyme Reaction
Aplysia californica mediated cyclisation of novel 3′-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5′-diphosphate …
Unique ligation properties of eukaryotic NAD+-dependent DNA ligase from Melanoplus sanguinipes entomopoxvirus
Redesign of Schistosoma mansoni NAD+ Catabolizing Enzyme: Active Site H103W Mutation Restores ADP-Ribosyl Cyclase Activity
Effective thermal oxidation of isopropanol by an NAD+ model
… salinarum: evidence that the gene sequence currently assigned to the NADP+-dependent enzyme is in fact that of the NAD+-dependent glutamate dehydrogenase
Examining the Relative Timing of Hydrogen Abstraction Steps during NAD+-Dependent Oxidation of Secondary Alcohols Catalyzed by Long-Chain d-Mannitol Dehydrogenase …
Dual control by regulatory gene fdsR of the fds operon encoding the NAD+‐linked formate dehydrogenase of Ralstonia eutropha
Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase
… of organometallic aqua complexes [Cp* Rh III (bpy)(OH2)] 2+ and [Cp* Rh III (6, 6′-Me2bpy)(OH2)] 2+ used as key catalysts in regioselective reduction of NAD+ …
Gene cloning and characterization of dihydrolipoamide dehydrogenase from Microbacterium luteolum: a useful enzymatic regeneration system of NAD+ from NADH
The formation of a diaphorase enzyme multilayer bound to a self-assembled monolayer for the mediated enzyme-catalyzed reduction of NAD+
Transformation and action of extracellular NAD+ in perfused rat and mouse livers
Arrest of cell cycle by inhibition of ribonucleotide reductase induces accumulation of NAD+ by Mn2+-supplemented growth of Corynebacterium ammoniagenes
C‐Terminal region of human NAD+‐dependent 15‐hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates
Preliminary report of NAD+-dependent amino acid dehydrogenase producing bacteria isolated from soil
Purification and characterization of cytoplasmic NAD+-dependent polypropylene glycol dehydrogenase from Stenotrophomonas maltophilia
Complex Gangliosides as Cell Surface Inhibitors for the Ecto-NAD+ Glycohydrolase of CD38
NAD+ hydrogenation on Au electrode deposited on modified glassy carbon
Non-toxic hydride energy source for biochemical and industrial venues: ORP and NAD+ reduction analyses
Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing …
Chain length analysis of ADP-ribose polymers generated by poly (ADP-ribose) polymerase (PARP) as a function of beta-NAD+ and enzyme concentrations.
The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before and after NAD+ and acetate binding suggest a dynamical reaction mechanism as a …
Partial cloning and expression analysis of genes encoding NAD+-dependent sorbitol dehydrogenase in pear bud during flower bud formation
Evidence for the existence of two soluble NAD+ kinase isoenzymes in Euglena gracilis Z
Expression of NAD+ dependent 15‐hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle
Detection of NAD+-dependent alcohol dehydrogenase activities in YR-1 strain of Mucor circinelloides, a potential bioremediator of petroleum contaminated soils
Characterization of rat and mouse NAD+-dependent 3α/17β/20α-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site …
The action of extracellular NAD+ on Ca2+ efflux, hemodynamics and some metabolic parameters in the isolated perfused rat liver
Primary Kinetic Isotope Effects on Hydride Transfer from Heterocyclic Compounds to NAD+ Analogues
An ancestral glutamine-dependent NAD+ synthetase revealed by poor kinetic synergism
Changes in soluble and membrane-bound isoforms of calcium-calmodulin-dependent and-independent NAD+ kinase, during the culture of after-ripened and dormant …
1.6 Å structure of an NAD+-dependent quinate dehydrogenase from Corynebacterium glutamicum
Diphtheria Toxin Catalyzed Hydrolysis of NAD+: Molecular Dynamics Study of Enzyme-Bound Substrate, Transition State, and Inhibitor
Changes in NAD+ kinase activity during germination of Phaseolus vulgaris and P. acutifolius, and effects of drought stress
Sol-gel immobilization of aldehyde dehydrogenase and NAD+ on screen-printed electrodes for designing of amperometric acetaldehyde biosensor
Cytosolic NADP phosphatases I and II from Arthrobacter sp. strain KM: Implication in regulation of NAD+/NADP+ balance
Potent and Selective Inhibitors of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD)
Presence and expression of NAD+-dependent sorbitol dehydrogenase and sorbitol-6-phosphate dehydrogenase genes in strawberry
Chromosomal characterization and localization of the NAD+-dependent histone deacetylase gene sirtuin 1 in the mouse
Threonine 11 of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase may interact with NAD+ during catalysis
Metabolic engineering of cofactors (NADH /NAD+) in Escherichia coli
The influence of electrode material on NAD+ oxidation
SUBCELLULAR LOCALIZATION OF THE NAD+-DEPENDENT ALCOHOL DEHYDROGENASE IN ENTAMOEBA HISTOLYTICA TROPHOZOITES
Mechanistic study on the role of the NAD+–NADH ratio in the glycolytic oscillation with a pyruvate sensor
NAD+-dependent glutamate dehydrogenase of the edible mushroom Agaricus bisporus: biochemical and molecular characterization
Effect of accessible immobilized NAD+ concentration on the bioaffinity chromatographic behavior of NAD+-dependent dehydrogenases using the kinetic locking-on …
Cloning and expression of NAD+-dependent L-arabinitol 4-dehydrogenase gene (ladA) of Aspergillus oryzae
Novel Synthesis, Properties, and NAD+-NADH Type Redox Ability of 1,3-Dimethylcyclohepta[4,5]pyrrolo[2,3-d]pyrimidine- 2,4(1,3H)-dionylium Ions Annulated with Additional Pyrrolo[2,3 …
… at the migrating hydrogen in the transition state of hydride transfer reactions from CH groups to hydride acceptors. Dynamics of the redox‐couple NADH‐NAD+
Host–guest properties of NAD+/NADH models
Thermostable NAD+-dependent (R)-specific secondary alcohol dehydrogenase from cholesterol-utilizingBurkholderia sp. AIU 652
Hydrogen-Transferred Radical Cations of NADH Model Compounds. 2. Sequential Electron−Proton Addition to NAD+
A cDNA encoding the highly immunodominant antigen of Strongyloides stercoralis: γ-subunit of isocitrate dehydrogenase (NAD+)
Anaerobic synthesis of succinic acid by recombinant Escherichia coli strains with activated NAD+-reducing pyruvate dehydrogenase complex
The action of extracellular NAD+ on gluconeogenesis in the perfused rat liver
Assignment of mitochondrial NAD+-specific isocitrate dehydrogenase (Beta subunit) gene (IDH3B) to human chromosome band 20p13 by in situ hybridization and …
Denaturation Studies by Fluorescence and Quenching of Thermophilic Protein NAD+-Glutamate Dehydrogenase from Thermus thermophilus HB8
Cloning, expression and characterization of NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase of adult Haemonchus contortus
Potentialities of expanded natural graphite as a new transducer for NAD+-dependent dehydrogenase amperometric biosensors
Rat NAD+-dependent 3α-hydroxysteroid dehydrogenase (AKR1C17): a member of the aldo-keto reductase family highly expressed in kidney cytosol
Crystal structure of 3-isopropylmalate dehydrogenase in complex with NAD+ and a designed inhibitor
Disulfide Bond Formation in Yeast NAD+-Specific Isocitrate Dehydrogenase
Electrochemical Preparation, Characterization, and Electrocatalytic Properties of OsPtCl6 Film Electrodes Towards Reduction of NAD+, Chloroacetic Acids, and …
Expression of NAD+-dependent isocitrate dehydrogenase in brown adipose tissue
Construction and Analyses of Tetrameric Forms of Yeast NAD+-Specific Isocitrate Dehydrogenase
NAD+ and metabolic regulation of age-related proteoxicity: A possible role for methylglyoxal?
Dexamethasone inhibits the induction of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells
NAD+-dependent mechanisms of disturbances of viability of brain cells during the acute period of hypoxic-ischemic perinatal injury
Induction of NAD+ dependent alcohol dehydrogenases with activity towards long chain aliphatic alcohols in mesophilic, thermophilic and extreme thermophilic …
Kinetic characterisation of recombinant Corynebacterium glutamicum NAD+-dependent LDH over-expressed in E. coli and its rescue of an lldD− phenotype in C …
A novel α-N-acetylgalactosaminidase family with an NAD+-dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens
Virtual screening of specific chemical compounds by exploring E.coli NAD+-dependent DNA ligase as a target for antibacterial drug discovery
Structure of the adenylation domain of NAD+-dependent DNA ligase from Staphylococcus aureus
Reduced glutathione inhibits β-NAD+-activated non-selective cation currents in the CRI-G1 rat insulin-secreting cell line
NAD+ Inhibits the self-splicing of the group I intron
NAD+-dependent DNA ligase (Rv3014c) from M. tuberculosis: Strategies for inhibitor design
13C NMR Analysis of Electrostatic Interactions between NAD+ and Active Site Residues of UDP-galactose 4-Epimerase: Implications for the Activation Induced by …
Physiological consequences of loss of allosteric activation of yeast NAD+-specific isocitrate dehydrogenase
NMR spectra and potentiometry studies of aluminum (III) binding with coenzyme NAD+ in acidic aqueous solutions
Rate enhancements brought about by uridine nucleotides in the reduction of NAD+ at the active site of UDP-galactose 4-epimerase
Liver parenchyma heterogeneity in the response to extracellular NAD+
… -linked immobilized NAD+ derivative using a rapid solid-phase modular approach: Suitability for use with the kinetic locking-on tactic for bioaffinity purification of NAD+ …
Molecular cloning and characterization of two inducible NAD+-adh genes encoding NAD+-dependent alcohol dehydrogenases from Acetobacter pasteurianus …
Determination of the transglycosidation activity of NAD+ glycohydrolases with 4-(2′-alkyl-sulfanyl-vinyl)-pyridine derivatives generating chromophoric NAD+ analogs
Highly stable amplified low-potential electrocatalytic detection of NAD+ at azure-chitosan modified carbon electrodes
Re‐engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the …
Protein nitration, PARP activation and NAD+ depletion may play a critical role in the pathogenesis of cyclophosphamide-induced hemorrhagic cystitis in the rat
Characterization of hybrid poly (acriflavine)/FAD films and their electrocatalytic properties with NAD+ and NADH
Automated assay for nicotinamide adenine dinucleotide (NAD+)†‡
Metabolism of cyclic ADP-ribose: A new role for NAD+ glycohydrolases
Design of a novel nucleoside analog as potent inhibitor of the NAD+ dependent deacetylase, SIRT2
… pathway as the main route for hexose catabolism in Bradyrhizobium sp. lacking Entner–Doudoroff pathway. A role for NAD+-dependent 6-phosphogluconate …
Analysis of Interactions with Mitochondrial mRNA Using Mutant Forms of Yeast NAD+-Specific Isocitrate Dehydrogenase
The electrochemical properties of NADH and NAD+ and their electrocatalytic reactions with tin hexachloroplatinate films
Structure and Function of Human NAD+-Linked 15-Hydroxyprostaglandin Dehydrogenase
Homotropic allosteric control in clostridial glutamate dehydrogenase: Different mechanisms for glutamate and NAD+?
NAD+ and NADP+ as Prosthetic Groups for Enzymes
NAD+ Consumption in Carcinogen-Treated Hamster Cells Overexpressing a Dominant Negative Mutant of Poly (ADP-ribose) Polymerase
Properties of an NAD+-dependent DNA ligase from the hyperthermophile Thermotoga maritima and its application in PCR amplification of long DNA fragments
Isolation and characterization of an NAD+-degrading bacterium PTX1 and its role in chromium biogeochemical cycle
Identification of NAD+-dependent isocitrate dehydrogenase 3 γ-like (IDH3GL) gene and its genetic polymorphisms
NAD+-consuming enzymes in the regulation of lung immune responses
Effect of AMP on mRNA Binding by Yeast NAD+-Specific Isocitrate Dehydrogenase
Gene Identification and Characterization of 5-Formyl-3-Hydroxy-2-Methylpyridine 4-Carboxylic Acid 5-Dehydrogenase, an NAD+-Dependent Dismutase
Crystallization and preliminary X-ray crystallographic analysis of yeast NAD+-specific isocitrate dehydrogenase
Molecular cloning and expression of the complete DNA sequence encoding NAD+-dependent acetaldehyde dehydrogenase fromAcinetobacter sp. strain HBS-2
Coupling of single-wall carbon nanotube and l-histidine on Ag microwires: New architectures for the assembling of NAD+ sensors
Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control
Botulinum Neurotoxin Types A, B, and E: Fragmentations by Autoproteolysis and Other Mechanisms Including by O-Phenanthroline–Dithiothreitol, and Association of the …
Characterization of soluble calcium calmodulin-dependent and-independent NAD+ kinases from Avena sativa seeds
Electrochemical Preparation of VPtCl6 Film and Its Electrocatalytic Properties with NAD+ and Sulfur Oxoanions
Characteristics of liposome immunosorbent assay (LISA) using liposomes encapsulating coenzyme β-NAD+
Developmental ontogeny of NAD+ kinase in the rat conceptus
NAD+ Mediated Differential Thermotolerance Between Chloroplastic and Cytosolic L‐myo‐Inositol‐1‐phosphate Synthase from Diplopterygium glaucum (Thunb.) …
Cloning and characterization of a glycerol‐3‐phosphate dehydrogenase (NAD+) gene from the halotolerant yeast Pichia farinosa
… Site-Directed Mutagenesis of Putative Key Residues in the Determination of Coenzyme Specificity in Clostridial NAD+-Dependent Glutamate Dehydrogenase
Control of Mitochondrial β-Oxidation at the Levels of [NAD+]/[NADH] and CoA Acylation
Nicotinoprotein (NAD+-containing) alcohol dehydrogenase: structural relationships and functional interpretations
ATP- and polyphosphate-dependent bacterial NAD+ kinases
Molecular cloning, expression, and immunolocalization of the NAD+-dependent glycerol 3-phosphate dehydrogenase (GPD) from Clonorchis sinensis
Novel allosteric properties produced by residue substitutions in the subunit interface of yeast NAD+-specific isocitrate dehydrogenase
NAD+ blocks H2O2‐induced HMGB1 translocation of PC12 cells and decreases survival of microglia
Isolation and RNA-binding analysis of NAD+-isocitrate dehydrogenases from Kluyveromyces lactis and Schizosaccharomyces pombe
NAD+ specificity of bacterial DNA ligase revealed
NAD+ treatment can block rotenone‐induced nuclear apoptotic changes of PC12 cells
A comparison of biospecific affinity chromatographic methodologies for the purification of NAD+-dependent dehydrogenases: studies with bovine l-lactate …
NAD+-malic enzyme affects nitrogenase activity of Mesorhizobium loti bacteroids in Lotus japonicus nodules
Agents for replacement of NAD+/NADH system in enzymatic reactions
Identification of NAD+ Synthetase from Streptococcus sobrinus as a B-Cell-Stimulatory Protein
GMX1777: a novel inhibitor of NAD+ biosynthesis via inhibition of nicotinamide phosphoribosyl transferase.
Flow monitoring of NADH consumption in bioassays based on packed-bed reactors bearing NAD+-dependent dehydrogenases: Determination of acetaldehyde using …
NAD+ and NADH concentrations in younger and older human adults
How to keep glycolytic metabolite concentrations constant when ATP/ADP and NADH/NAD+ change
Determination of NAD+ and NADH level in a single cell under hydrogen peroxide stress by capillary electrophoresis
Expression of Hsd11K (NAD+ Dependent 11β-Hydroxysteroid Dehydrogenase) Promoter Constructs in Renal Cell Lines
Inhibition of Nicotinoprotein (NAD+-Containing) Alcohol Dehydrogenase by trans-4-(N,N-Dimethylamino)-Cinnamaldehyde Binding to the Active Site
Biochemical characterization of isocitrate dehydrogenase from Methylococcus capsulatus reveals a unique NAD+-dependent homotetrameric enzyme
Basis for Half-Site Ligand Binding in Yeast NAD+-Specific Isocitrate Dehydrogenase
A “Stripping” Ligand Tactic for Use with the Kinetic Locking-on Strategy: Its Use in the Resolution and Bioaffinity Chromatographic Purification of NAD+-Dependent …
INTERACTION OF NAD+ AND NADP+ WITH NATIVE AND PYRIDOXAL PHOSPHATE-MODIFIED GLUCOSE 6-PHOSPHATE DEHYDROGENASE PURIFIED …
Application of an Electrochemical NAD+ Recycling System Involving a String-Like Carbon Fiber to an Enzyme Reactor
Purification and Properties of NAD+-dependent Sorbitol Dehydrogenase from Bacillus fructosus
NAD+ induces C6 glioma cell death by generating oxidative stress and increasing intracellular calcium concentrations
NAD+ administration can profoundly decrease the brain injury induced by hypoxia‐ischemia
NAD+‐dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of mitochondrial ribosomal protein L10
Crystallization and preliminary X-ray crystallographic analysis of yeast NAD+-specific isocitrate dehydrogenase. Corrigendum
Subcellular and Extracellular Trafficking of NAD+ and Cyclic ADP-Ribose: A New Way for Regulating Intracellular Calcium Homeostasis
Mannitol increases lactic acid production by shifting NADH/NAD+ ratio inhibiting ethanol production
Effect of selected NAD+ analogues on mitochondria activity and proliferation of endothelial EA. hy926 cells
Aromatic interactions at atom-to-atom contact and just beyond: a case study of protein interactions of NAD+/NADP+
Effects of Electrochemical Pretreatments on NADH Oxidation at NAD+‐Modified Carbon Paste Electrodes
An exploratory ab initio conformational analysis of selected fragments of nicotinamide adenine dinucleotide (NAD+). Part I: 5-deoxyribose nicotinamide N-glycoside
1H, 13C, and 15N backbone assignments and secondary structure for the 60.8 kD dimer of the NAD+ synthetase from Bacillus subtilis
Enzymatic synthesis of beta-NAD+ selectively marked with tritium at adenine and its use for determining the activity of poly (ADP-ribose) polymerase
NAD+ catabolism in pheochromocytoma rat cells.
Electrocatalytic Reduction of NAD+ at Multi‐walled Carbon Nanotubes Modified Electrode
Crystallization and preliminary X-ray crystallographic analysis of NAD+-dependent DNA ligase from Thermus filiformis
Recycling of vitamin B12 and NAD+ within the Pdu microcompartment of Salmonella enterica
MonoADP-Ribosylation of the NAD+-Dependent Alcohol Dehydrogenase from Entamoeba histolytica
Determination of intracellular NAD+ levels to study biological damage induced by pesticides
Oxytocin released from mouse hypothalamus and nerve endings by extracellular applicaion of beta-NAD+ and cyclic ADP-ribose
Regeneration and Aging: Regulation by Sirtuins and the NAD+ Salvage Pathway
Preparation and characterization of CePtCl6 films and their electrocatalytic properties with NAD+, l-cystine and sulfur oxoanions
Intercellular and intracellular trafficking of NAD+ and NAD+ precursors, intermediate metabolites and signal metabolites
In-situ SERS Raman Spectra of NAD+ on Silver Electrode Recorded during a Potential Scanning Procedure
Structure of the Sir2 Family of NAD+-Dependent Histone/Protein Deacetylases
Liposome immune lysis assay of antibodies by liposomes encapsulating coenzyme β-NAD+
Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD+ regeneration
Redefining neuroprotective gene therapeutic strategies: Lessons learned from caloric restriction and NAD+ metabolism
An exploratory ab initio conformational analysis of selected fragments of nicotinamide adenine dinucleotide (NAD+). Part II: adenosine
Synthesis, Properties, and NAD+-NADH-Type Redox Ability of 14-Substituted 1,3-Dimethyl-5,10-methanocycloundeca[4,5]pyrrolo[2,3-d]pyrimidine-2,4(1,3H) …
Crystallization and preliminary crystallographic analysis of NAD+-preferring aldohexose dehydrogenase from the thermoacidophilic archaeon Thermoplasma …
Mutational Analysis of Bacterial NAD+-dependent DNA Ligase: Role of Motif IV in Ligation Catalysis
On the nonspecific degradation of NAD+ to nicotinamide riboside
Use of a Reverse Micelle System for Study of Oligomeric Structure of NAD+-Reducing Hydrogenase from Ralstonia eutropha H16.
Effect of NAD+ against radiation injury and its dose-effect relationship
Delayed treatment of NAD+ can restore intracellular ATP levels and prevent PC12 cell death induced by oxidative stress
Nicotinamidase modulation of nicotinamide levels and NAD+ synthesis separately affect development and physiology of multiple organ systems in C. elegans
The catalysis of NAD+ on methanol anode oxidation electrode for direct methanol fuel cell
Searching for the Source: Determining NAD+ Concentrations in the Yeast Vacuole
Threonine 11 is involved in the interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
Complex gangliosides as cell surface inhibitors for the ecto-NAD+ glycohydrolase of CD38
Effects of deamido‐NAD+ on self‐splicing of primary transcripts of phage T4 thymidylate synthase gene
1: Activation of poly (adp-ribose) polymerase-1 contributes to NAD+ depletion and impaired NAD+ dependent mitochondrial respiration following status epilepticus
Electrochemical behaviour of NAD+ -modified carbon paste electrodes
NAD+ Consumption in Carcinogen-Treated Hamster Cells Overexpressing a Dominant Negative Mutant of Poly (ADP-ribose) Polymerase
Sodium activated potassium channels (K (Na)) are modulated by nicotinamide adenine dinucleotide (NAD+) in adult dorsal root ganglion (DRG) neurons
The action of extracellular NAD+ in the liver of healthy and tumor-bearing rats: Model analysis of the tumor-induced modified response
A Methylotrophic Thermotolerant Actinomycete With a NAD+-Dependent Methanol Dehydrogenase
Crystallization and preliminary crystallographic studies of the NAD+-dependent deacetylase HST1 from Saccharomyces cerevisiae
Crystallization and X-ray analysis of NH3-dependent NAD+ synthetase from Helicobacter pylori
Characterization of iron hexachloroplatinate films and their electrocatalytic properties with NAD+, hemoglobin and O2
Anaerobic synthesis of succinic acid by Escherichia coli strains with activated NAD+ reducing pyruvate dehydrogenase complex
Bioluminescent method for determination of concentration metabolic substrates and NAD+ in the lymphocytes
Functional Analysis of Rex, a Sensor of the NADH/NAD+ Redox Poise in Streptomyces Coelicolor
Effect of Overexpression of NAD+-dependent Malic Enzyme on Anaerobic Mixed Acid Fermentation of E. coli FMJ39
Polymer modified electrodes for the reversible oxidation-reduction of NAD+/NADH for use within amperometric biosensors
Crystallographic report: Crystal structures of organometallic aqua complexes [Cp*RhIII(bpy)(OH2)]2+ and [Cp*RhIII(6,6′‐Me2bpy)(OH2)]2+ used as key catalysts in …
Kinetic properties of fractions of extracellular NAD+ nucleosidase fromStreptococcus pyogenes as an example of host selection by a pathogen: Possible role of …
Development of a Reagentless Amperometric Ethanol Biosensor Based on Yeast Alcohol Dehydrogenase and its Coenzyme, NAD+, Coimmobilized on a Carbon …
Electron transfer from NADH bound to horse liver alcohol dehydrogenase (NAD+ dependent dehydrogenase): Visualisation of the activity in the enzyme crystals and …
Unusual enzymatic hydrolysis of NAD by solubilized form of NAD+ glycohydrolase
The role of yeast NAD+-isocitrate dehydrogenase in mitochondrial translation
Regulation of NAD+– Specific Isocitrate Dehydrogenase from Pythium ultimum
NAD+ Induces Autophagy of Neuro2a Cells by Increasing Oxidative Stress
NAD+ Treatment Can Attenuate the Oxidative Stress‐Induced, PARP‐Mediated ATP Depletion in PC12 Cells
NAD+ treatment can prevent multiple rotenone‐induced apoptotic changes of PC12 cells
Activation of P2X7 receptor can lead to NAD+ release from astrocytes
Integrating metabolic control by NAD+ sensors
Glyceraldehyde-3-phosphate dehydrogenase is posttranslationally modified by NAD+ in enterohemorrhagic Escherichia coli
NAD+ can induce autophagy of Neuro2a cells and PC12 cells
NAD+ Treatment Induces Tumor Cell Necrosis by P2X7 Receptor‐Independent Pathways
Simultaneous determination of the reduction of NAD+ and NADP+ by glutamate dehydrogenase supports preferential utilization of NAD+ in glutamate oxidation
Studies of NAD+-mediated melanogenesis.
MP-01.18: Extracellular beta-NAD+ increases intracellular free calcium in human detrusor muscle cells and induces relaxation of human detrusor detrusor muscle
NAD+ as a Vasoactive Signal in the Retinal Microvasculature
Atomic resolution study of the substrate binding sites in NH3-dependent NAD+ synthetase from B. subtilis
Effects of NAD+ on cell morphology and viability of Hela cell Lines exposed to 6-aminonicotinamide
Metabolism of NAD+ in Nuclei of Saccharomyces cerevisiae during Stimulation of Its Biosynthesis by Nicotinamide
Abstract B98: Induction of metabolic and oxidative stresses by the novel inhibitor of NAD+ biosynthesis, GMX 1778, for specific killing of human glioblastomas
Design, synthesis of biologically interesting dinucleotides, ADPR, cADPR and NAD+ alkyne (bisphonate) analogs.
Effects of Cytosolic NADH/NAD+ Levels on Ca2+ Release from the Sarcoplasmic Reticulum in Rat Ventricular Myocytes
NAD+ metabolism in lymphocytes of patients affected by B-cell chronic lymphocytic leukaemia.
Nicotinamide Phosphoribosyltransferase (Nampt) Induces NAD+ / SIRT1 Mediated Deacetylation of p53 in Myeloid Cells.
Nampt is a Critical Regulator of NAD+ Synthesis in Cardiomyocytes
Relationship between Nicotinaamide Adenine Dinucleotide (NAD+) Metabolism and Inositol Biosynthesis
An electrochemical study of NAD+ interaction with a polycrystalline gold surface
Investigation of NAD+ binding to glyceraldehyde 3-phosphate dehydrogenase
Light-induced Death Of Photoreceptor And RPE Cells: Role Of Zinc And NAD+
Nicotinamide Phosphoribosyltransferase (Nampt) Induces NAD+/SIRT1 Mediated Deacetylation of FOXO3a in Myeloid Cells.
… E2 levels in human colorectal cancer liver metastases is associated with differences in NAD+ levels and expression of NAD+-dependent 15-prostaglandin …
Boron complexation with NAD+ inhibits ADP-ribosyl cyclase non-competitively
Characterization of ammonia transport in NAD+ synthetase from Mycobacterium tuberculosis
A Novel NAD+-Dependent Aldehyde Dehydrogenase from Klebsiella pneumoniae Utilizes 3-Hydroxypropionaldehyde as a Major Substrate
Attempts to change coenzyme specificity of NAD+ dependent formate dehydrogenase from Candida metylica by rational design
The effects of etoposide and niacin deficiency on bone marrow NAD+ and telomere length in Long-Evans rats
Impaired NAD+ Metabolism in Neuronal Dysfunction in Critical Conditions
Virtual screening of specific chemical compounds by exploring E. coli NAD+-dependent DNA ligase as a target for antibacterial…
Targeting NAD+ Salvage Pathway Induces Autophagy in Multiple Myeloma Cells
Catalysis of Mitochondrial NADH→NAD+ Transhydrogenation in Adult Ascaris suum (Nematoda)
PARP-1-induced cell death requires NAD+ depletion and mitochondrial permeability transition
Glutamine-dependent NAD+ Synthetase
Production of 3-Hydroxypropionic acid by a Recombinant Escherichia coli with a Novel NAD+-Dependent Aldehyde Dehydrogenase Encoded by the puuC gene of …
Synthesis and characterization of NAD+-modified silica: a convenient immobilization of biomolecule via its phosphate group
The Preparation of Butyrylated NAD+ Type of Biological Molecules
Regulation Of Cardiac Na+ Channel By NAD+/NADH
1.6 Å crystal structure of an NAD+ dependent quinate dehydrogenase from Corynebacterium glutamicum
Investigation of the Structure, Function, and Regulation of Quinolinate Synthase: the Iron-Sulfur Cluster Enzyme Involved in Prokaryotic NAD+ Biosynthesis
Pilot scale production and isolation of recombinant NAD+-and NADPH+-specific formate dehydrogenase
New pathways of NAD+ metabolism and longevity
Alteration of CD38 expression and NAD+ metabolism induced by Doxorubicin in bone marrow cells
Anaerobic synthesis of succinic acid by Escherichia coli strains with activated NAD+ reducing pyruvate dehydrogenase complex
L-lactate: NAD+ Oxide-reductase (LDH; EC. 1.1. 1.27) isoenzymes expression during embryonary development of siamese fighting fish Betta splendens (REGAN …
NAD +‐Reducing [NiFe]‐Hydrogenase
Bioluminescent method for determination of concentration metabolic substrates and NAD+ in the lymphocytes
New strategies for co-immobilization of dehydrogenases, NAD+ cofactor and redox mediators in sol-gel thin films for bioelectrocatalytic applications
Relaxing the cofactor specificity of formate dehydrogenase from NAD+ to NADP+
Characterization of a benzoylformate decarboxylase and a NAD+/NADP+‐dependent benzaldehyde dehydrogenase from Pseudomonas stutzeri ST‐201
Regulation of the NAD+‐dependent histone deacetylase Sirt1 in conditions of muscle use and disuse
Affinity purification of NAD+-dependent formate dehydrogenase (EC 1.2. 1.2) and activity of FDH in miniature enzyme bioreactors
Novel Class of NAD+-dependent 15-Hydroxyprostaglandin Dehydrogenase Inhibitors
Understanding the kinetic and structural features of plasmodium falciparum Sir2: a NAD+ dependent deacetylase
Overproduction of NAD+ and 5′-inosine monophosphate in the presence of 10 µM Mn2+ by a mutant ofCorynebacterium ammoniageneswith thermosensitive nucleotide …
Delayed Wallerian degeneration of sympathetic axons: a potential role of NAD+ and the MEK/Erk pathway
Intermediates along the NAD+ cyclisation reaction pathway of ADP-ribosyl cyclase
NAD+ IMPROVES SURVIVAL OF ENDOTOXEMIC MICE.: 225
Novel Class of NAD+-dependent 15-HydroxyprostagJandin Dehydrogenase Inhibitors
NAD+-Linked Methylglyoxal Dehydrogenase in Streptomyces coelicolor A3(2)
Isolation, cloning and expression of NAD+ glycohydrolase from neurospora crassa
Localization of NAD+ Synthesis Enzymes in the Pathogenic Yeast Candida glabrata
… nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism. VOLUME 284 …
Regulatory function of sucrose in gene expression of lipase and NAD+-and NADP+-dependent isocitric dehydrogenase in organs of germinating yellow lupine seeds …
Function and regulation of the human NAD+-dependent protein deacetylase SIRT2
22 NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10
Flow Injection Procedure for Determination of NAD+ Using Immobilized Enzyme with Spectrophotometric Detection
Correction to Kinetics of the Hydride Reduction of an NAD+ Analogue by Isopropyl Alcohol in Aqueous and Acetonitrile Solutions: Solvent Effects, Deuterium Isotope …
Enzyme Properties and mRNA Expression of an NAD+ Scavenging System: NatV and NadV of Vibrio parahaemolyticus Phage KVP40
… of 10 nM FK866, 100 μg/ml VA, 500 μM BU, or their combination. 48 h later, NAD+ levels were determined by enzymatic cycling assay. NAD+ values were normalized …
Levels of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease. Evidence for involvement of TNF-α
Detection of the Activity of NAD+ Dependent Sorbitol Dehydrogenase and Its cDNA Cloning but No Activity of Sorbitol-6-phosphate Dehydrogenase in Strawberry
NAD+ and sirtuins in aging and disease
NAD+ in aging, metabolism, and neurodegeneration
NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus
The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice
The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
Biosensor reveals multiple sources for mitochondrial NAD+
NAD+ intermediates: the biology and therapeutic potential of NMN and NR
Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue
NAD+ metabolism: Bioenergetics, signaling and manipulation for therapy
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
NAD+ in aging: molecular mechanisms and translational implications
Extreme vulnerability of IDH1 mutant cancers to NAD+ depletion
Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
SARM1 activation triggers axon degeneration locally via NAD+ destruction
Elevated microRNA‐34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT
NAD+-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease
De novo NAD+ synthesis enhances mitochondrial function and improves health
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression
Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis
De novo NAD+ biosynthetic impairment in acute kidney injury in humans
The SARM1 toll/interleukin-1 receptor domain possesses intrinsic NAD+ cleavage activity that promotes pathological axonal degeneration
Activation of SIRT3 by the NAD+ precursor nicotinamide riboside protects from noise-induced hearing loss
Normalization of NAD+ Redox Balance as a Therapy for Heart Failure
It takes two to tango: NAD+ and sirtuins in aging/longevity control
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease
Emerging therapeutic roles for NAD+ metabolism in mitochondrial and age-related disorders
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD+/SIRT1 reduction
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation
NAD+ replenishment improves lifespan and healthspan in ataxia telangiectasia models via mitophagy and DNA repair
Targeting sirtuin 1 to improve metabolism: all you need is NAD+?
NAD+/NADH and skeletal muscle mitochondrial adaptations to exercise
A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ decline
Targeted, LCMS-based metabolomics for quantitative measurement of NAD+ metabolites
Hepatic NAD+ deficiency as a therapeutic target for non‐alcoholic fatty liver disease in ageing
Sources and implications of NADH/NAD+ redox imbalance in diabetes and its complications
… -label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy …
Modulating NAD+ metabolism, from bench to bedside
SIRT1-mediated eNAMPT secretion from adipose tissue regulates hypothalamic NAD+ and function in mice
NAD+ metabolism: A therapeutic target for age-related metabolic disease
Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio
AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD+ elevation
The NAD+-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells
NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Environment dictates dependence on mitochondrial complex I for NAD+ and aspartate production and determines cancer cell sensitivity to metformin
The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel …
Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion
A conserved NAD+ binding pocket that regulates protein-protein interactions during aging
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion
NAD+ biosynthesis, aging, and disease
Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation
A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome
Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging
NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns
Axon self-destruction: new links among SARM1, MAPKs, and NAD+ metabolism
Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio
NAMPT-mediated NAD+ biosynthesis is essential for vision in mice
Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism
The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
Dual inhibition of the lactate transporters MCT1 and MCT4 is synthetic lethal with metformin due to NAD+ depletion in cancer cells
Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo …
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells
NAD+ salvage pathway in cancer metabolism and therapy
SoNar, a highly responsive NAD+/NADH sensor, allows high-throughput metabolic screening of anti-tumor agents
Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
Efficient Catalytic Interconversion between NADH and NAD+ Accompanied by Generation and Consumption of Hydrogen with a Water-Soluble Iridium Complex at …
Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation
The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA
Genetically encoded fluorescent indicator for imaging NAD+/NADH ratio changes in different cellular compartments
NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains
TIR domain proteins are an ancient family of NAD+-consuming enzymes
Inhibition of de novo NAD+ synthesis by oncogenic URI causes liver tumorigenesis through DNA damage
CD38-NAD+ axis regulates immunotherapeutic anti-tumor T cell response
ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion
NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response
Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells …
The Rnf Complex of Clostridium ljungdahlii Is a Proton-Translocating Ferredoxin:NAD+ Oxidoreductase Essential for Autotrophic Growth
The NAD+/PARP1/SIRT1 axis in aging
Nicotinamide mononucleotide, an NAD+ precursor, rescues age-associated susceptibility to AKI in a sirtuin 1–dependent manner
Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk
NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis
Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases
Flavin-Based Electron Bifurcation, Ferredoxin, Flavodoxin, and Anaerobic Respiration With Protons (Ech) or NAD+ (Rnf) as Electron Acceptors: A Historical …
Nicotinamide mononucleotide inhibits post-ischemic NAD+ degradation and dramatically ameliorates brain damage following global cerebral ischemia
Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence
Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells
A need for NAD+ in muscle development, homeostasis, and aging
The ferredoxin: NAD+ oxidoreductase (Rnf) from the acetogen Acetobacterium woodii requires Na+ and is reversibly coupled to the membrane potential
ARTD1 (PARP1) activation and NAD+ in DNA repair and cell death
Pharmacological activation of NQO1 increases NAD+ levels and attenuates cisplatin-mediated acute kidney injury in mice
Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment
Why NAD+ declines during aging: it’s destroyed
The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+
Targeting NAD+ in metabolic disease: New insights into an old molecule
Exploring the therapeutic space around NAD+
Enhancing NAD+ salvage pathway reverts the toxicity of primary astrocytes expressing amyotrophic lateral sclerosis-linked mutant superoxide dismutase 1 …
… Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion–Mediated CytotoxicityTMZ Induces NAD+ Depletion in IDH1 …
NAD+ administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia
Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes
Obesity Is Associated With Low NAD+/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins
Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition
Enhancing NAD+ salvage metabolism is neuroprotective in a PINK1 model of Parkinson’s disease
An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma
SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation
Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD
NAMPT-mediated NAD+ biosynthesis in adipocytes regulates adipose tissue function and multi-organ insulin sensitivity in mice
Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration
NAD+ as the link between oxidative stress, inflammation, caloric restriction, exercise, DNA repair, longevity, and health span
Dietary restriction involves NAD+‐dependent mechanisms and a shift toward oxidative metabolism
Regulation of poly (ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase
The oxygen‐tolerant and NAD+‐dependent formate dehydrogenase from Rhodobacter capsulatus is able to catalyze the reduction of CO2 to formate
MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells
Sirtuins: NAD+-dependent deacetylase mechanism and regulation
Exogenous NAD+ supplementation protects H9c2 cardiac myoblasts against hypoxia/reoxygenation injury via Sirt1‐p53 pathway
Eukaryotic RNA 5′-end NAD+ capping and DeNADding
Identification of NAD+ capped mRNAs in Saccharomyces cerevisiae
In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD+/NADH redox state
Highly efficient 5′ capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase
Evidence for a Direct Effect of the NAD+ Precursor Acipimox on Muscle Mitochondrial Function in Humans
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses
NAD+-Metabolizing Ectoenzymes in Remodeling Tumor–Host Interactions: The Human Myeloma Model
NAD+ protects against EAE by regulating CD4+ T-cell differentiation
NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy
Therapeutic potential of boosting NAD+ in aging and age-related diseases
NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in …
Redox dysregulation in schizophrenia revealed by in vivo NAD+/NADH measurement
Silibinin Restores NAD+ Levels and Induces the SIRT1/AMPK Pathway in Non-Alcoholic Fatty Liver
The Current State of NAD+‐Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets
Emerging potential benefits of modulating NAD+ metabolism in cardiovascular disease
Investigating the sensitivity of NAD+-dependent sirtuin deacylation activities to NADH
NAD+ in DNA repair and mitochondrial maintenance
Adipose tissue NAD+-homeostasis, sirtuins and poly (ADP-ribose) polymerases-important players in mitochondrial metabolism and metabolic health
Head to Head Comparison of Short-Term Treatment with the NAD+ Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese …
Restoration of Mitochondrial NAD+ Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells
CapZyme-seq comprehensively defines promoter-sequence determinants for RNA 5′ capping with NAD+
Intracellular NAD+ depletion enhances bortezomib-induced anti-myeloma activity
NAD+: A key metabolic regulator with great therapeutic potential
Silybin inhibits NLRP3 inflammasome assembly through the NAD+/SIRT2 pathway in mice with nonalcoholic fatty liver disease
NAD+-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1
Methylotrophic Bacillus methanolicus Encodes Two Chromosomal and One Plasmid Born NAD+ Dependent Methanol Dehydrogenase Paralogs with …
Exogenous NAD+ decreases oxidative stress and protects H2O2-treated RPE cells against necrotic death through the up-regulation of autophagy
Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy
The peroxisomal NAD+ carrier of Arabidopsis thaliana transports coenzyme A and its derivatives
Accurate Measurement of Nicotinamide Adenine Dinucleotide (NAD+) with High-Performance Liquid Chromatography
Exploring NAD+ metabolism in host–pathogen interactions
NNMT activation can contribute to the development of fatty liver disease by modulating the NAD+ metabolism
NAD+ Biosynthesis and Signaling in Plants
Poly (ADP-ribose) polymerase-1-induced NAD+ depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation
MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption
Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence
Troxerutin improves hepatic lipid homeostasis by restoring NAD+-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice
Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress
Cytosolic NADH-NAD+ Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging
Ketone-Based Metabolic Therapy: Is Increased NAD+ a Primary Mechanism?
… formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD+-dependent formate dehydrogenase
… myeloma cells are equipped with ectoenzymes belonging to canonical and non-canonical adenosinergic pathways and produce adenosine from ATP and NAD+
The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control
The PduQ Enzyme Is an Alcohol Dehydrogenase Used to Recycle NAD+ Internally within the Pdu Microcompartment of Salmonella enterica
Detection of cerebral NAD+ in humans at 7T
Intracellular redox state revealed by in vivo 31P MRS measurement of NAD+ and NADH contents in brains
The NAD+ salvage pathway supports PHGDH-driven serine biosynthesis
Live-Cell Imaging of Cytosolic NADH–NAD+ Redox State Using a Genetically Encoded Fluorescent Biosensor
Weight Loss Is Associated With Increased NAD+/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue
NAD+ metabolism and NAD+-dependent enzymes: promising therapeutic targets for neurological diseases
Detection of cerebral NAD+ by in vivo 1H NMR spectroscopy
Rhodium-Coordinated Poly(arylene-ethynylene)-alt-Poly(arylene-vinylene) Copolymer Acting as Photocatalyst for Visible-Light-Powered NAD+/NADH Reduction
NAD+ Content and Its Role in Mitochondria
Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach
Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1 …
Engineering NADH/NAD+ ratio in Halomonas bluephagenesis for enhanced production of polyhydroxyalkanoates (PHA)
NMNAT: It’s an NAD+ synthase… It’sa chaperone… It’sa neuroprotector
The potential regulatory roles of NAD+ and its metabolism in autophagy
Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism
The NAD+ precursor nicotinamide riboside decreases exercise performance in rats
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid
Hydrogen Evolution from Aliphatic Alcohols and 1,4-Selective Hydrogenation of NAD+ Catalyzed by a [C,N] and a [C,C] Cyclometalated Organoiridium Complex at …
Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site,“selectivity pocket” and NAD+-binding site
Spectroscopic and kinetic properties of the molybdenum-containing, NAD+-dependent formate dehydrogenase from Ralstonia eutropha
NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD+ Pools
Regulation of serine-threonine kinase Akt activation by NAD+-dependent deacetylase SIRT7
Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors
NAD+-dependent SIRT1 deactivation has a key role on ischemia–reperfusion-induced apoptosis
c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration
Regulatory effects of NAD+ metabolic pathways on sirtuin activity
Augmentation of NAD+ by NQO1 attenuates cisplatin-mediated hearing impairment
Ketogenic Diet Modulates NAD+-Dependent Enzymes and Reduces DNA Damage in Hippocampus
Treatment with NAD+ inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune …
Bioorthogonally Functionalized NAD+ Analogues for In‐Cell Visualization of Poly(ADP‐Ribose) Formation
Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum
Chain‐Terminating and Clickable NAD+ Analogues for Labeling the Target Proteins of ADP‐Ribosyltransferases
Exogenous NAD+ administration significantly protects against myocardial ischemia/reperfusion injury in rat model
NAD+ Kinase as a Therapeutic Target in CancerTargeting NAD+ Kinase
Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle
Engineering NAD+ availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production
NAD+ and nicotinamide: sex differences in cerebral ischemia
Theobromine increases NAD+/Sirt-1 activity and protects the kidney under diabetic conditions
Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program
The NAD+-Dependent Family of Sirtuins in Cerebral Ischemia and Preconditioning
Streptococcus mutans NADH Oxidase Lies at the Intersection of Overlapping Regulons Controlled by Oxygen and NAD+ Levels
NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion
The Effects of NAD+ on Apoptotic Neuronal Death and Mitochondrial Biogenesis and Function after Glutamate Excitotoxicity
Targeting NAD+/PARP DNA Repair Pathway as a Novel Therapeutic Approach to SDHB-Mutated Cluster I Pheochromocytoma and ParagangliomaCombination …
Electrocatalytic oxidation of NADH at electrogenerated NAD+ oxidation product immobilized onto multiwalled carbon nanotubes/ionic liquid nanocomposite …
The NAD+ salvage pathway modulates cancer cell viability via p73
Mitochondrial Dysfunction and NAD+ Metabolism Alterations in the Pathophysiology of Acute Brain Injury
Nutritional Ketosis Increases NAD+/NADH Ratio in Healthy Human Brain: An in Vivo Study by 31P-MRS
NAD+ dependent deacetylase Sirtuin 5 rescues the innate inflammatory response of endotoxin tolerant macrophages by promoting acetylation of p65
Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD+ biosynthetic machinery in mammalian …
Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in …
CD38 is methylated in prostate cancer and regulates extracellular NAD+
Social memory, amnesia, and autism: brain oxytocin secretion is regulated by NAD+ metabolites and single nucleotide polymorphisms of CD38
Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery …
Mitochondrial Matrix Ca2+ Accumulation Regulates Cytosolic NAD+/NADH Metabolism, Protein Acetylation, and Sirtuin Expression
NBCe1 mediates the regulation of the NADH/NAD+ redox state in cortical astrocytes by neuronal signals
Troxerutin protects against 2, 2′, 4, 4′-tetrabromodiphenyl ether (BDE-47)-induced liver inflammation by attenuating oxidative stress-mediated NAD+-depletion
Addition of Exogenous NAD+ Prevents Mefloquine-Induced Neuroaxonal and Hair Cell Degeneration through Reduction of Caspase-3-Mediated Apoptosis …
Dietary proanthocyanidins boost hepatic NAD+ metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats
Efficient Whole-Cell Biocatalyst for Acetoin Production with NAD+ Regeneration System through Homologous Co-Expression of 2,3-Butanediol Dehydrogenase and …
NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans
NAD+: The convergence of DNA repair and mitophagy
A Single Organoiridium Complex Generating Highly Active Catalysts for both Water Oxidation and NAD+/NADH Transformations
Occurrence of ferredoxin: NAD+ oxidoreductase activity and its ion specificity in several Gram-positive and Gram-negative bacteria
NAD+ augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
Structural basis of the redox switches in the NAD+-reducing soluble [NiFe]-hydrogenase
Imaging the NADH:NAD+ Homeostasis for Understanding the Metabolic Response of Mycobacterium to Physiologically Relevant Stresses
Rice NAD+-dependent histone deacetylase OsSRT1 represses glycolysis and regulates the moonlighting function of GAPDH as a transcriptional activator of glycolytic …
The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes
Regulation of NAD (H) pool and NADH/NAD+ ratio by overexpression of nicotinic acid phosphoribosyltransferase for succinic acid production in Escherichia coli …
Development of a novel reagentless, screen-printed amperometric biosensor based on glutamate dehydrogenase and NAD+, integrated with multi-walled carbon …
Alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase controls dietary niacin requirements for NAD+ synthesis
The Inhibitory Effects of Purple Sweet Potato Color on Hepatic Inflammation Is Associated with Restoration of NAD+ Levels and Attenuation of NLRP3 Inflammasome …
NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents
NAD+ administration decreases doxorubicin-induced liver damage of mice by enhancing antioxidation capacity and decreasing DNA damage
Intracellular NAD+ levels are associated with LPS-induced TNF-α release in pro-inflammatory macrophages
NAD+ biosynthesis and salvage – a phylogenetic perspective
Improved Catalytic Activity of Ruthenium–Arene Complexes in the Reduction of NAD+
NAD+ deficiency in age-related mitochondrial dysfunction
Inhibitors of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5
Cofactor engineering to regulate NAD+/NADH ratio with its application to phytosterols biotransformation
PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 …
NAD+ in cancer prevention and treatment: pros and cons
Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice
The evolving role of the NAD+/nicotinamide metabolome in skin homeostasis, cellular bioenergetics, and aging
Half-sandwich rhodium (III) transfer hydrogenation catalysts: Reduction of NAD+ and pyruvate, and antiproliferative activity
NAD+ deficits in age-related diseases and cancer
Targeting NAD+ degradation: The therapeutic potential of flavonoids for Alzheimer’s disease and cognitive frailty
Bioinspired Design of Alcohol Dehydrogenase@nano TiO2 Microreactors for Sustainable Cycling of NAD+/NADH Coenzyme
The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription
Partial Reversal of Skeletal Muscle Aging by Restoration of Normal NAD+ Levels
Benzophenones from an Endophytic Fungus, Graphiopsis chlorocephala, from Paeonia lactiflora Cultivated in the Presence of an NAD+-Dependent HDAC Inhibitor
Ca2+ signals of astrocytes are modulated by the NAD+/NADH redox state
Reduction of flavodoxin by electron bifurcation and sodium ion-dependent reoxidation by NAD+ catalyzed by ferredoxin-NAD+ reductase (Rnf)
α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) …
More to NAD+ than meets the eye: a regulator of metabolic pools and gene expression in Arabidopsis
NAD+-dependent synthesis of a 5′-phospho-ADP-ribosylated RNA/DNA cap by RNA 2′-phosphotransferase Tpt1
Secretion of Quinolinic Acid, an Intermediate in the Kynurenine Pathway, for Utilization in NAD+ Biosynthesis in the Yeast Saccharomyces cerevisiae
Direct electron transfer-type four-way bioelectrocatalysis of CO2/formate and NAD+/NADH redox couples by tungsten-containing formate dehydrogenase adsorbed on …
Resveratrol attenuates excessive ethanol exposure induced insulin resistance in rats via improving NAD+/NADH ratio
Extracellular NAD+: a danger signal hindering regulatory T cells
Reversible Active Site Sulfoxygenation Can Explain the Oxygen Tolerance of a NAD+-Reducing [NiFe] Hydrogenase and Its Unusual Infrared Spectroscopic …
NAD+ repletion produces no therapeutic effect in mice with respiratory chain complex III deficiency and chronic energy deprivation
Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD+-SIRT axis in articular chondrocytes is involved in osteoarthritis
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, leads to altered carbohydrate metabolism in …
OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease
Methanol/Oxygen Enzymatic Biofuel Cell Using Laccase and NAD+-Dependent Dehydrogenase Cascades as Biocatalysts on Carbon Nanodots Electrodes
Overexpression of CYB5R3 and NQO1, two NAD+‐producing enzymes, mimics aspects of caloric restriction
The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
The effect of succinate on brain NADH/NAD+ redox state and high energy phosphate metabolism in acute traumatic brain injury
Real-time and high-throughput analysis of mitochondrial metabolic states in living cells using genetically encoded NAD+/NADH sensors
In vitro metabolic engineering for the salvage synthesis of NAD+
Epigenetic stimulation of polyketide production in Chaetomium cancroideum by an NAD+-dependent HDAC inhibitor
Protective effect of nicotinamide adenine dinucleotide (NAD+) against spinal cord ischemia–reperfusion injury via reducing oxidative stress-induced neuronal …
Sirtuin 1 (SIRT1) Deacetylase Activity and NAD+/NADH Ratio Are Imperative for Capsaicin-Mediated Programmed Cell Death
NAMPT-Mediated Salvage Synthesis of NAD+ Controls Morphofunctional Changes of Macrophages
A screen using iPSC-derived hepatocytes reveals NAD+ as a potential treatment for mtDNA depletion syndrome
Genetically encoded probes for NAD+/NADH monitoring
High protein intake is associated with low plasma NAD+ levels in a healthy human cohort
Linking DNA damage, NAD+/SIRT1, and aging
Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism
Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory …
Investigation of NADH Binding, Hydride Transfer, and NAD+ Dissociation during NADH Oxidation by Mitochondrial Complex I Using Modified Nicotinamide …
Mechanism of Sirt1 NAD+-dependent protein deacetylase inhibition by cysteine S-nitrosation
Direct electron transfer-type bioelectrocatalytic interconversion of carbon dioxide/formate and NAD+/NADH redox couples with tungsten-containing formate …
… vibrational spectroscopy reveals the FeS cluster composition and active site vibrational properties of an O 2-tolerant NAD+-reducing [NiFe] hydrogenase
Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia
Identification of novel resistance mechanisms to NAMPT inhibition via the de novo NAD+ biosynthesis pathway and NAMPT mutation
NAD+-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism
NAD+ accumulation during pollen maturation in Arabidopsis regulating onset of germination
Crosstalk of Signaling and Metabolism Mediated by the NAD+/NADH Redox State in Brain Cells
Coenzyme Engineering of a Hyperthermophilic 6-Phosphogluconate Dehydrogenase from NADP+ to NAD+ with Its Application to Biobatteries
The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target
Reactive oxygen species production in cardiac mitochondria after complex I inhibition: modulation by substrate-dependent regulation of the NADH/NAD+ ratio
Inorganic pyrophosphatase defects lead to cell cycle arrest and autophagic cell death through NAD+ depletion in fermenting yeast
Calorie restriction and NAD+/sirtuin counteract the hallmarks of aging
Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration
Characterization of the SIRT family of NAD+-dependent protein deacetylases in the context of a mammalian model of hibernation, the thirteen-lined ground squirrel
NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins
Minireview: NAD+, a Circadian Metabolite with an Epigenetic Twist
The NAD+-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status
Chronic alcohol binging injures the liver and other organs by reducing NAD+ levels required for sirtuin’s deacetylase activity
Structural Diversity of New C13-Polyketides Produced by Chaetomium mollipilium Cultivated in the Presence of a NAD+-Dependent Histone Deacetylase Inhibitor
NAD+/NADH metabolism and NAD+-dependent enzymes in cell death and ischemic brain injury: current advances and therapeutic implications
The Rice NAD+-Dependent Histone Deacetylase OsSRT1 Targets Preferentially to Stress- and Metabolism-Related Genes and Transposable Elements
NAD+ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study
NAD+ acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration
Facile chemoenzymatic synthesis of a novel stable mimic of NAD+
Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion
The Streptococcus pyogenes NAD+ glycohydrolase modulates epithelial cell PARylation and HMGB1 release
High Affinity Crown Ether Complexes in Water: Thermodynamic Analysis, Evidence of Crystallography and Binding of NAD+
Vibrio Phage KVP40 Encodes a Functional NAD+ Salvage Pathway
Novel type II and monomeric NAD+ specific isocitrate dehydrogenases: phylogenetic affinity, enzymatic characterization and evolutionary implication
Role of NAD+, Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders
Photoelectrochemical glucose biosensor based on a dehydrogenase enzyme and NAD+/NADH redox couple using a quantum dot modified pencil graphite electrode
A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD+/NADH ratio and activating …
In vivo 31P MRS assessment of intracellular NAD metabolites and NAD+/NADH redox state in human brain at 4 T
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD+
Enhancement of succinate yield by manipulating NADH/NAD+ ratio and ATP generation
NAD+ and sirtuins in retinal degenerative diseases: A look at future therapies
Binding free energy calculations and biological testing of novel thiobarbiturates as inhibitors of the human NAD+ dependent histone deacetylase Sirt2
A Novel Metabolite of Antituberculosis Therapy Demonstrates Host Activation of Isoniazid and Formation of the Isoniazid-NAD+ Adduct
Metabolism of isoniazid by neutrophil myeloperoxidase leads to isoniazid-NAD+ adduct formation: a comparison of the reactivity of isoniazid with its known human …
Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD+ dissociation
NAD+ regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4+ CD25+ Foxp3+ T cells independent
SIRT1 and NAD+ precursors: Therapeutic targets in multiple sclerosis a review
Application of a novel thermostable NAD(P)H oxidase from hyperthermophilic archaeon for the regeneration of both NAD+ and NADP+
Synthesis and Characterization of 4,11-Diaminoanthra[2,3-b]furan-5,10-diones: Tumor Cell Apoptosis through tNOX-Modulated NAD+/NADH Ratio and SIRT1
Heterologous production of extreme alkaline thermostable NAD+-dependent formate dehydrogenase with wide-range pH activity from Myceliophthora thermophila
Emissive Synthetic Cofactors: An Isomorphic, Isofunctional, and Responsive NAD+ Analogue
Extracellular Degradation Into Adenosine and the Activities of Adenosine Kinase and AMPK Mediate Extracellular NAD+-Produced Increases in the …
Reprogramming the glycolytic pathway for increased hydrogen production in cyanobacteria: metabolic engineering of NAD+-dependent GAPDH
Adenosine 5′‐diphosphate‐ribose is a neural regulator in primate and murine large intestine along with β‐NAD+
Intracellular NAD+ depletion induces autophagic death in multiple myeloma cells
NAMPT-mediated NAD biosynthesis as the internal timing mechanism: in NAD+ world, time is running in its own way
Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration
Augmentation of NAD+ levels by enzymatic action of NAD (P) H quinone oxidoreductase 1 attenuates adriamycin-induced cardiac dysfunction in mice
Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD+) synthetase inhibitors as potential antitubercular agents
Multifunctional Roles of NAD+ and NADH in Astrocytes
Effect of sulfonamidoethylenediamine substituents in Ru II arene anticancer catalysts on transfer hydrogenation of coenzyme NAD+ by formate
The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism
NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus
Roles of NAD+, PARP-1, and sirtuins in cell death, ischemic brain injury, and synchrotron radiation X-ray-induced tissue injury
NADH dehydrogenase-like behavior of nitrogen-doped graphene and its application in NAD+-dependent dehydrogenase biosensing
Gene silencing of indoleamine 2, 3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth
Improvement of mitochondrial NAD+/FAD+-linked state-3 respiration by caffeine attenuates quinolinic acid induced motor impairment in rats: Implications in …
Dunnione ameliorates cisplatin-induced small intestinal damage by modulating NAD+ metabolism
Surrogate analyte approach for quantitation of endogenous NAD+ in human acidified blood samples using liquid chromatography coupled with electrospray ionization …
The resurgence of NAD+
Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity
High-throughput screening of coenzyme preference change of thermophilic 6-phosphogluconate dehydrogenase from NADP+ to NAD+
Emissive Synthetic Cofactors: Enzymatic Interconversions of tzA Analogues of ATP, NAD+, NADH, NADP+, and NADPH
Release, neuronal effects and removal of extracellular β‐nicotinamide adenine dinucleotide (β‐NAD+) in the rat brain
Oxyresveratrol stimulates mucin production in an NAD+-dependent manner in human intestinal goblet cells
… from ion mobility-mass spectrometry, infrared spectroscopy, and molecular dynamics simulations on nicotinamide adenine dinucleotide structural dynamics: NAD+ vs …
… strategy based on dumbbell probe-mediated rolling circle amplification-responsive G-quadruplex formation for highly sensitive and selective detection of NAD+ or …
The respiratory chain provides salt stress tolerance by maintaining a low NADH/NAD+ ratio in Zymomonas mobilis
SIRT3, a Mitochondrial NAD+-Dependent Deacetylase, Is Involved in the Regulation of Myoblast Differentiation
Uridine monophosphate synthetase enables eukaryotic de novo NAD+ biosynthesis from quinolinic acid
A functional link between NAD+ homeostasis and N-terminal protein acetylation in Saccharomyces cerevisiae
Protective pleiotropic effect of flavonoids on NAD+ levels in endothelial cells exposed to high glucose
Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD+, for enhancing the production of 3-hydroxypropionic acid
New function for Escherichia coli xanthosine phophorylase (xapA): genetic and biochemical evidences on its participation in NAD+ salvage from nicotinamide
New insights into the roles of NAD+-poly (ADP-ribose) metabolism and poly (ADP-ribose) glycohydrolase
The NADase-Negative Variant of the Streptococcus pyogenes Toxin NAD+ Glycohydrolase Induces JNK1-Mediated Programmed Cellular Necrosis
NAD+-linked alcohol dehydrogenase 1 regulates methylglyoxal concentration in Candida albicans
… from Cordyceps militaris fermentation supernatant using preparative HPLC and evaluation of its antibacterial activity as an NAD+-dependent DNA ligase …
Effect of alternative NAD+-regenerating pathways on the formation of primary and secondary aroma compounds in a Saccharomyces cerevisiae glycerol-defective …
Comparative metabolomic profiling reveals that dysregulated glycolysis stemming from lack of salvage NAD+ biosynthesis impairs reproductive development …
Enhanced aldehyde dehydrogenase activity by regenerating NAD+ in Klebsiella pneumoniae and implications for the glycerol dissimilation pathways
Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD+ protects the heart against pressure overload
The NAD+-dependent deacetylase, Bifidobacterium longum Sir2 in response to oxidative stress by deacetylating SigH (σH) and FOXO3a in Bifidobacterium longum …
Vitamin B3 forms as precursors to NAD+: are they safe?
Extracellular NAD+ inhibits human neutrophil apoptosis
Exploitation of a Laccase/Meldola’s Blue System for NAD+ Regeneration in Preparative Scale Hydroxysteroid Dehydrogenase‐Catalyzed Oxidations
ROS-Mediated 15-Hydroxyprostaglandin dehydrogenase degradation via cysteine oxidation promotes NAD+-Mediated Epithelial-Mesenchymal Transition
Differential release of β‐NAD+ and ATP upon activation of enteric motor neurons in primate and murine colons
Inhibition of an NAD+ Salvage Pathway Provides Efficient and Selective Toxicity to Human Pluripotent Stem Cells
NAD+ treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells
An NAD+-dependent novel transcription factor controls stage conversion in Entamoeba
Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD+ and Fluoroalcohols Define Strained Michaelis Complexes
Altered Expression of Mitochondrial NAD+ Carriers Influences Yeast Chronological Lifespan by Modulating Cytosolic and Mitochondrial Metabolism
Reduced Ssy1-Ptr3-Ssy5 (SPS) signaling extends replicative life span by enhancing NAD+ homeostasis in Saccharomyces cerevisiae
Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells
Measuring NAD+ levels in mouse blood and tissue samples via a surrogate matrix approach using LC–MS/MS
Quantitative Analysis of Bioactive NAD+ Regenerated by NADH Electro-oxidation
Direct electrocatalytic reduction of coenzyme NAD+ to enzymatically-active 1, 4-NADH employing an iridium/ruthenium-oxide electrode
New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2
Visfatin is involved in TNFα-mediated insulin resistance via an NAD+/Sirt1/PTP1B pathway in 3T3-L1 adipocytes
Bioelectrocatalytic NAD+/NADH inter-conversion: transformation of an enzymatic fuel cell into an enzymatic redox flow battery
Melatonin protects chondrocytes from impairment induced by glucocorticoids via NAD+-dependent SIRT1
Structural and biochemical characterisation of a NAD+-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial …
NAD+/NADH homeostasis affects metabolic adaptation to hypoxia and secondary metabolite production in filamentous fungi
Insights into the mechanism of bovine CD38/NAD+ glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates
Enzyme biosensor for androsterone based on 3α-hydroxysteroid dehydrogenase immobilized onto a carbon nanotubes/ionic liquid/NAD+ composite electrode
Aldehyde dehydrogenase 1A1 increases NADH levels and promotes tumor growth via glutathione/dihydrolipoic acid-dependent NAD+ reduction
Effects of overexpression of NAPRTase, NAMNAT, and NAD synthetase in the NAD (H) biosynthetic pathways on the NAD (H) pool, NADH/NAD+ ratio, and succinic …
NAD+-Carrying Mesoporous Silica Nanoparticles Can Prevent Oxidative Stress-Induced Energy Failures of Both Rodent Astrocytes and PC12 Cells
Tumor-associated NADH oxidase (tNOX)-NAD+-sirtuin 1 axis contributes to oxaliplatin-induced apoptosis of gastric cancer cells
Additive and enhanced fluorescence effects of hairpin DNA template-based copper nanoparticles and their application for the detection of NAD+
Enzymatic and spectroscopic properties of a thermostable [NiFe]‑hydrogenase performing H2-driven NAD+-reduction in the presence of O2
NAD+-converting enzymes in neuronal and glial cells: CD38 as a novel target for neuroprotection
NAD+ administration significantly attenuates synchrotron radiation X-ray-induced DNA damage and structural alterations of rodent testes
Ferredoxin:NAD+ Oxidoreductase of Thermoanaerobacterium saccharolyticum and Its Role in Ethanol Formation
Indirubin and NAD+ prevent mitochondrial ischaemia/reperfusion damage in fatty livers
Loss of NADH Oxidase Activity in Streptococcus mutans Leads to Rex-Mediated Overcompensation in NAD+ Regeneration by Lactate Dehydrogenase
Repeated production of L-xylulose by an immobilized whole-cell biocatalyst harboring L-arabinitol dehydrogenase coupled with an NAD+ regeneration system
Gene Transfers Shaped the Evolution of De Novo NAD + Biosynthesis in Eukaryotes
NAD+ maintenance attenuates light induced photoreceptor degeneration
TEMPOL increases NAD+ and improves redox imbalance in obese mice
Restoring stem cells—all you need is NAD+
Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture
Metabolism Dealing with Thermal Degradation of NAD+ in the Hyperthermophilic Archaeon Thermococcus kodakarensis
One-step fabrication of integrated disposable biosensor based on ADH/NAD+/meldola’s blue/graphitized mesoporous carbons/chitosan nanobiocomposite for ethanol …
NAD+ metabolism in age-related hearing loss
Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity
Vesicle Encapsulation of a Nonbiological Photochemical System Capable of Reducing NAD+ to NADH
Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD+/H Binding to Mitochondrial Apoptosis-Inducing Factor
Benchmark Analysis of Native and Artificial NAD+-Dependent Enzymes Generated by a Sequence-Based Design Method with or without Phylogenetic Data
Quantitation of NAD+: Why do we need to measure it?
Resveratrol delays Wallerian degeneration in a NAD+ and DBC1 dependent manner
Intrinsic directionality of migrating vascular smooth muscle cells is regulated by NAD+ biosynthesis
Dunnione protects against experimental cisplatin-induced nephrotoxicity by modulating NQO1 and NAD+ levels
KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts
The circadian NAD+ metabolism: impact on chromatin remodeling and aging
Binding of NAD+-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus
Improvement of NADPH bioavailability in Escherichia coli by replacing NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase GapA with NADP+-dependent GapB …
Enhancement of NAD+-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial …
Mitigation of gamma-radiation induced abasic sites in genomic DNA by dietary nicotinamide supplementation: metabolic up-regulation of NAD+ biosynthesis
Electron Paramagnetic Resonance and Electron Spin Echo Studies of Co2+ Coordination by Nicotinamide Adenine Dinucleotide (NAD+) in Water Solution
SA1/SA2 cohesion proteins and SIRT1-NAD+ deacetylase modulate telomere homeostasis in cumulus cells and are eligible biomarkers of ovarian aging
Indoleamine 2, 3-Dioxygenase activity increases NAD+ production in IFN-γ–stimulated human primary mononuclear cells
Blocking NAD+/CD38/cADPR/Ca2+ pathway in sepsis prevents organ damage
NAD+ Is a Food Component That Promotes Exit from Dauer Diapause in Caenorhabditis elegans
Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis
Using Fractional Intensities of Time-resolved Fluorescence to Sensitively Quantify NADH/NAD+ with Genetically Encoded Fluorescent Biosensors
Molecular Clone and Expression of a NAD+-Dependent Glycerol-3-Phosphate Dehydrogenase Isozyme Gene from the Halotolerant alga Dunaliella salina
Investigation of the NADH/NAD+ ratio in Ralstonia eutropha using the fluorescence reporter protein Peredox
Ligation-Based qPCR-Amplification Assay for Radiolabel-Free Detection of ATP and NAD+ with High Selectivity and Sensitivity
Biochemical and molecular characterization of NAD+-dependent isocitrate dehydrogenase from the ethanologenic bacterium Zymomonas mobilis
Secondary NAD+ deficiency in the inherited defect of glutamine synthetase
Discovery of Potent Inhibitors of Schistosoma mansoni NAD+ Catabolizing Enzyme
Dunnione ameliorates cisplatin ototoxicity through modulation of NAD+ metabolism
Fabrication of Flexible Arrayed Lactate Biosensor Based on Immobilizing LDH-NAD+ on NiO Film Modified by GO and MBs
Live cell imaging of cytosolic NADH/NAD+ ratio in hepatocytes and liver slices
Mobile phones electromagnetic radiation and NAD+-dependent isocitrate dehydrogenase as a mitochondrial marker in asthenozoospermia
The 1.8 Å cholix toxin crystal structure in complex with NAD+ and evidence for a new kinetic model
Glycerol and environmental factors: effects on 1,3‐propanediol production and NAD+ regeneration in Lactobacillus panis PM1
Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase
Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 …
Two-step mechanism and step-arrest mutants of Runella slithyformis NAD+-dependent tRNA 2′-phosphotransferase Tpt1
Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD+ homeostasis and contributes to longevity
Characterization of the mitochondrial NAD+-dependent isocitrate dehydrogenase of the oleaginous yeast Rhodosporidium toruloides
Functional effects of active site mutations in NAD+-dependent formate dehydrogenases on transformation of hydrogen carbonate to formate
Increased cellular NAD+ level through NQO1 enzymatic action has protective effects on bleomycin-induced lung fibrosis in mice
Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD+-dependent polynucleotide ligases
A Key Enzyme of the NAD+ Salvage Pathway in Thermus thermophilus: Characterization of Nicotinamidase and the Impact of Its Gene Deletion at High Temperatures
Analysis of polymorphic residues reveals distinct enzymatic and cytotoxic activities of the Streptococcus pyogenes NAD+ glycohydrolase
Reactivity of a fac-ReCl (α-diimine)(CO) 3 complex with an NAD+ model ligand toward CO 2 reduction
Discovery of bacterial NAD+-dependent DNA ligase inhibitors: improvements in clearance of adenosine series
Overexpression in a non-native halophilic host and biotechnological potential of NAD+-dependent glutamate dehydrogenase from Halobacterium salinarum strain …
Stabilisation of the NAD+-reducing soluble [NiFe]-hydrogenase from Ralstonia eutropha H16 through modification with methoxy-poly (ethylene) glycol
… Direct Protein Targets of Poly‐ADP‐Ribose Polymerases (PARPs) Using Engineered PARP Variants—Orthogonal Nicotinamide Adenine Dinucleotide (NAD+) …
Hairpin stabilized fluorescent silver nanoclusters for quantitative detection of NAD+ and monitoring NAD+/NADH based enzymatic reactions
Crystallographic and solution studies of NAD+-and NADH-bound alkylhydroperoxide reductase subunit F (AhpF) from Escherichia coli provide insight into …
Toxicity of Melaleuca alternifolia essential oil to the mitochondrion and NAD+/NADH dehydrogenase in Tribolium confusum
MopA, the Mn Oxidizing Protein From Erythrobacter sp. SD-21, Requires Heme and NAD+ for Mn(II) Oxidation
Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part I: Aminoalkoxypyrimidine …
NAD+/NADH tethering on mwnts-bucky papers for glucose dehydrogenase-based anodes
Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD+, NADPH, or NAD+/10‐Oxogeranial: Reaction Mechanisms
Identification of Protein Substrates of Specific PARP Enzymes Using Analog-Sensitive PARP Mutants and a “Clickable” NAD+ Analog
Roles of Nicotinamide Adenine Dinucleotide (NAD+) in Biological Systems
De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells
Nutritional Energy Stimulates NAD+ Production to Promote Tankyrase-Mediated PARsylation in Insulinoma Cells
Neuronal and extraneuronal release of ATP and NAD+ in smooth muscle
Effects of exogenous nicotinamide adenine dinucleotide (NAD+) in the rat heart are mediated by P2 purine receptors
NAD+ influx through connexin hemichannels prevents poly (ADP-ribose) polymerase-mediated astrocyte death
A unique homodimeric NAD+‐linked isocitrate dehydrogenase from the smallest autotrophic eukaryote Ostreococcus tauri
NAD+ attenuates bilirubin-induced hyperexcitation in the ventral cochlear nucleus by inhibiting excitatory neurotransmission and neuronal excitability
NAD+-dependent HDAC inhibitor stimulates Monascus pigment production but inhibit citrinin
A scalable metabolite supplementation strategy against antibiotic resistant pathogen Chromobacterium violaceum induced by NAD+/NADH+ imbalance
Molecular evolutionary patterns of NAD+/Sirtuin aging signaling pathway across taxa
Binding of NAD+ and L-threonine induces stepwise structural and flexibility changes in Cupriavidus necator L-threonine dehydrogenase
NAD+: A big player in cardiac and skeletal muscle remodeling and aging
NAD+ as a Hydride Donor and Reductant
NAD+ accumulation as a metabolic off switch for orthodox pollen
Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD 2 H
Cerebrospinal fluid levels of inflammation, oxidative stress and NAD+ are linked to differences in plasma carotenoid concentrations
Structure–activity relationship studies and biological characterization of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
NAD+-aminoaldehyde dehydrogenase candidates for 4-aminobutyrate (GABA) and β-alanine production during terminal oxidation of polyamines in apple fruit
Elucidation of a Self-Sustaining Cycle in Escherichia coli l-Serine Biosynthesis That Results in the Conservation of the Coenzyme, NAD+
An NAD+-Dependent Sirtuin Depropionylase and Deacetylase (Sir2La) from the Probiotic Bacterium Lactobacillus acidophilus NCFM
Impact of the Iron–Sulfur Cluster Proximal to the Active Site on the Catalytic Function of an O2-Tolerant NAD+-Reducing [NiFe]-Hydrogenase
Electrocatalytic interconversion of NADH and NAD+ by Escherichia coli flavohemoglobin
… of cortical neurons to hypoxic injury via the activation of downstream targets of the PI3K pathway and the normalization of the levels of PARP activity, ATP, and NAD+
Kinetic mechanism and fidelity of nick sealing by Escherichia coli NAD+-dependent DNA ligase (LigA)
Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding l-glutamine plus glycine instead of NAD+ in β-cyclodextrin–water system
Acyl-CoA-binding domain containing 3 modulates NAD+ metabolism through activating poly(ADP-ribose) polymerase 1
Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) …
Fluorescence-Based Screening Assays for the NAD+-Dependent Histone Deacetylase smSirt2 from Schistosoma mansoni
Reduction of 2-methoxy-1, 4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory …
Identification of activation of tryptophan–NAD+ pathway as a prominent metabolic response to thermally oxidized oil through metabolomics-guided biochemical …
Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD+-dependent deacetylases
A Novel Type II NAD+-Specific Isocitrate Dehydrogenase from the Marine Bacterium Congregibacter litoralis KT71
Conserved water-mediated recognition and dynamics of NAD+ (carboxamide group) to hIMPDH enzyme: water mimic approach toward the design of isoform …
NAD+ Treatment Can Prevent Rotenone-Induced Increases in DNA Damage, Bax Levels and Nuclear Translocation of Apoptosis-Inducing Factor in Differentiated …
Salvaging hope: Is increasing NAD+ a key to treating mitochondrial myopathy?
Efficient one-step production of (S)-1-phenyl-1, 2-ethanediol from (R)-enantiomer plus NAD+–NADPH in-situ regeneration using engineered Escherichia coli
Influence of GSH synthesis inhibition on temporal distribution of NAD+/NADH during vascular endothelial cells proliferation
Modulating NAD+ metabolism to prevent acute kidney injury
Kinetics of electrochemical reduction of NAD+ on a glassy carbon electrode
Biofuel Cell Anodes Integrating NAD+-Dependent Enzymes and Multiwalled Carbon Nanotube Papers
Nicotinamide Adenine Dinucleotide (NAD+) Repletion Attenuates Bupivacaine-Induced Neurotoxicity
A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD+-SIRT1 signaling
M. tuberculosis Sliding β-Clamp Does Not Interact Directly with the NAD+ -Dependent DNA Ligase
Tributyltin induces G2/M cell cycle arrest via NAD+-dependent isocitrate dehydrogenase in human embryonic carcinoma cells
NAD+ promotes assembly of the active tetramer of aldehyde dehydrogenase 7A1
Stability enhancement of an O2-tolerant NAD+-reducing [NiFe]-hydrogenase by a combination of immobilisation and chemical modification
NAD+-dependent enzymes at the endoplasmic reticulum
Tunneling of redox enzymes to design nano-probes for monitoring NAD+ dependent bio-catalytic activity
Investigation of the action of poly (ADP-ribose)-synthesising enzymes on NAD+ analogues
Discovery of a new metal and NAD+-dependent formate dehydrogenase from Clostridium ljungdahlii
Role of NAD+-Dependent Malate Dehydrogenase in the Metabolism of Methylomicrobium alcaliphilum 20Z and Methylosinus trichosporium OB3b
Molecular Characterization of NAD+-Dependent DNA Ligase from Wolbachia Endosymbiont of Lymphatic Filarial Parasite Brugia malayi
GAPDH with NAD+-binding site mutation competitively inhibits the wild-type and affects glucose metabolism in cancer
Quantification of Protein Copy Number in Yeast: The NAD+ Metabolome
Identification through structure-based methods of a bacterial NAD+-dependent DNA ligase inhibitor that avoids known resistance mutations
Differential fumarate binding to Arabidopsis NAD+-malic enzymes 1 and-2 produces an opposite activity modulation
Disruption of NAD+ binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions
Integrated omics-analysis reveals Wnt-mediated NAD+ metabolic reprogramming in cancer stem-like cells
Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD+
Label-free biosensor based on dsDNA-templated copper nanoparticles for highly sensitive and selective detection of NAD+
Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part 2: 4-amino-pyrido [2, 3-d] pyrimidin …
NAD+ regeneration in a microreactor using permeabilized baker’s yeast cells
EPR and potentiometric studies of copper (II) binding to nicotinamide adenine dinucleotide (NAD+) in water solution
Lack of the NAD+-dependent glycerol 3-phosphate dehydrogenase impairs the function of transcription factors Sip4 and Cat8 required for ethanol utilization in …
Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase
The role of NAD+-dependent isocitrate dehydrogenase 3 subunit α in AFB1 induced liver lesion
NAD-Glycohydrolase Depletes Intracellular NAD+ and Inhibits Acidification of Autophagosomes to Enhance Multiplication of Group A Streptococcus in …
Longevity focuses on NAD+
Studies of lysine cyclodeaminase from Streptomyces pristinaespiralis: Insights into the complex transition NAD+ state
Effect of NAD+-dependent formate dehydrogenase on anaerobic respiration of Shewanella oneidensis MR-1
ADH based NAD+ regeneration in a microreactor
NAD+ controls neural stem cell fate in the aging brain
p53, DNA damage, and NAD+ homeostasis
Biochemical analysis of the NAD+-dependent malate dehydrogenase, a substrate of several serine/threonine protein kinases of Mycobacterium tuberculosis
NAD+-independent aldehyde oxidase catalyzes cofactor balanced 3-hydroxypropionic acid production in Klebsiella pneumoniae
Effects of Nicotinamide Adenine Dinucleotide (NAD+) and Diadenosine Tetraphosphate (Ap4A) on Electrical Activity of Working and Pacemaker Atrial Myocardium in …
Structure Guided Understanding of NAD+ Recognition in Bacterial DNA Ligases
Mutations that allow SIR2 orthologs to function in a NAD+-depleted environment
β-Lapachone ameliorates murine cisplatin nephrotoxicity: NAD+, NQO1, and SIRT1 at the crossroads of metabolism, injury, and inflammation
Characterization of Frex as an NADH sensor for in vivo applications in the presence of NAD+ and at various pH values
The β-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly (ADP) ribosylation
Methods for Using a Genetically Encoded Fluorescent Biosensor to Monitor Nuclear NAD+
α-Tocopherol administration blocks adaptive changes in cell NADH/NAD+ redox state and mitochondrial function leading to inhibition of gastric mucosa cell …
Ligand binding and structural changes associated with allostery in yeast NAD+-specific isocitrate dehydrogenase
Giardia duodenalis GlSir2. 2, homolog of SIRT1, is a nuclear-located and NAD+-dependent deacethylase
Comparative Study of C∧N and N∧C Type Cyclometalated Ruthenium Complexes with a NAD+/NADH Function
NAD+-specific glutamate dehydrogenase (EC.1.4.1.2) in Streptomyces coelicolor; in vivo characterization and the implication for nutrient-dependent secondary …
An NAD+ biosynthetic pathway enzyme functions cell non‐autonomously in C. elegans development
A [32P] NAD+-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors
Influence exogenous nicotinamide adenine dinucleotide (NAD+) on contractile and bioelectric activity of the rat heart
Methylation gets into rhythm with NAD+-SIRT1
Subcellular and intercellular traffic of NAD+, NAD+ precursors and NAD+-derived signal metabolites and second messengers: Old and new topological paradoxes
Hyperthermophilic Archaeon Thermococcus kodakarensis Utilizes a Four-Step Pathway for NAD+ Salvage through Nicotinamide Deamination
Structures of Medicago truncatula L-Histidinol Dehydrogenase Show Rearrangements Required for NAD+ Binding and the Cofactor Positioned to Accept a …
A ternary complex model of Sirtuin4-NAD+-Glutamate dehydrogenase
The NAD+/NADH redox couple—Insights from the perspective of electrochemical energy transformation and biomimetic chemistry
Antimicrobial Activity of Adenine-Based Inhibitors of NAD+-Dependent DNA Ligase
Nicotinamide adenine dinucleotide (NAD+) and cell aging
polyethyleneimine wrapped carbon nanotubes in situ formed gold nanoparticles decorated with DNA and NAD+ as a novel bioeletrochemical sensing platform
Negishi cross-coupling enabled synthesis of novel NAD+-dependent DNA ligase inhibitors and SAR development
Steroid Receptor Coactivator 1 is an Integrator of Glucose and NAD+/NADH Homeostasis
MicroRNAs Emerge as Modulators of NAD+-Dependent Energy Metabolism in Skeletal Muscle
Concomitant cell‐free biosynthesis of optically pure D‐(−)‐acetoin and xylitol via a novel NAD+ regeneration in two‐enzyme cascade
The combination of NAD+-dependent deacetylase gene deletion and the interruption of gluconeogenesis causes increased glucose metabolism in budding …
Stress response of NAD+-dependent formate dehydrogenase in Gossypium hirsutum L. grown under copper toxicity
Boosting NAD+ for the prevention and treatment of liver cancer
Purification and Characterization of an NAD+-Dependent XylB-Like Aryl Alcohol Dehydrogenase Identified in Acinetobacter baylyi ADP1
A modified chromogenic assay for determination of the ratio of free intracellular NAD+/NADH in streptococcus mutans
A high effective NADH-ferricyanide dehydrogenase coupled with laccase for NAD+ regeneration
From fragments to leads: novel bacterial NAD+-dependent DNA ligase inhibitors
Homology Modeling of NAD+-Dependent DNA Ligase of the Wolbachia Endosymbiont of Brugia malayi and Its Drug Target Potential Using Dispiro-Cycloalkanones
Xylitol production by NAD+-dependent xylitol dehydrogenase (xdhA)-and L-arabitol-4-dehydrogenase (ladA)-disrupted mutants of Aspergillus oryzae
Global kinetic analysis of mammalian E3 reveals pH-dependent NAD+/NADH regulation, physiological kinetic reversibility, and catalytic optimum
Kinetics and structural features of dimeric glutamine-dependent bacterial NAD+ synthetases suggest evolutionary adaptation to available metabolites
Molecular docking and structural analysis of cofactor-protein interaction between NAD+ and 11β-hydroxysteroid dehydrogenase type 2
Probing the catalytic mechanism of bovine CD38/NAD+ glycohydrolase by site directed mutagenesis of key active site residues
… of [nicotinamide-2H3] NAD+ from [2H4] nicotinamide and [2H4] nicotinic acid in human HepG2N cells and involvement of 2H/1H exchange at the redox site of NAD+ …
The structural requirements of organophosphorus insecticides (OPI) for reducing chicken embryo NAD+ content in OPI-induced teratogenesis in chickens
Purification and Characterization of NAD+-Dependent Salicylaldehyde Dehydrogenase from Carbaryl-Degrading Pseudomonas sp. Strain C6
IcmQ in the Type 4b secretion system contains an NAD+ binding domain
Physicochemical and catalytic properties of NAD+– dependent malate dehydrogenase isoforms from maize mesophyll
Lipopolysaccharide-induced murine embryonic resorption involves nitric oxide-mediated inhibition of the NAD+-dependent 15-hydroxyprostaglandin …
Increased productivity of l-2-aminobutyric acid and total turnover number of NAD+/NADH in a one-pot system through enhanced thermostability of l-threonine …
The role of diadenosine pentaphosphate and nicotinamide adenine dinucleotide (NAD+) as potential nucleotide comediators in the adrenergic regulation of cardiac …
Crystallization and preliminary X-ray analysis of the NAD+-reducing [NiFe] hydrogenase from Hydrogenophilus thermoluteolus TH-1
Identification and characterization of a mycobacterial NAD+-dependent alcohol dehydrogenase with superior reduction of diacetyl to (S)-acetoin
Characterization of rabbit morphine 6-dehydrogenase and two NAD+-dependent 3α (17β)-hydroxysteroid dehydrogenases
Effect of Exogenous Extracellular Nicotinamide Adenine Dinucleotide (NAD+) on Bioelectric Activity of the Pacemaker and Conduction System of the Heart
HLADH-catalyzed synthesis of β-amino acids, assisted by continuous electrochemical regeneration of NAD+ in a filter press microreactor
Sirtuins, NAD+, aging, and disease: A retrospective and prospective overview
Thermodynamics and kinetics of NAD+ adsorption on a glassy carbon electrode
Identification of a Novel Pathway of Transforming Growth Factor-β1 Regulation by Extracellular NAD+ in Mouse Macrophages: IN VITRO AND IN SILICO …
Complete steady-state rate equation for DNA ligase and its use for measuring product kinetic parameters of NAD+-dependent DNA ligase from Haemophilus …
Presence of extracellular NAD+ and NADH in cultures of wood-degrading fungi
Cloning and characterization of a novel NAD+‐dependent glyceraldehyde‐3‐phosphate dehydrogenase gene from Candida glycerinogenes and use of its promoter
Streptococcus pyogenes quinolinate‐salvage pathway—structural and functional studies of quinolinate phosphoribosyl transferase and NH3‐dependent NAD+ …
Assays for NAD+-Dependent Reactions and NAD+ Metabolites
NAD+‐Dependent Dehydrogenase PctP and Pyridoxal 5′‐Phosphate Dependent Aminotransferase PctC Catalyze the First Postglycosylation Modification of the …
Nanoparticle-tethered NAD+ with in situ cofactor regeneration
Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic …
Activity of liver mitochondrial NAD+-dependent dehydrogenases of the krebs cycle in rats with acetaminophen-induced hepatitis developed under conditions of …
A Simple Procedure to Fabricate Paper Biosensor and Its Applicability—NADH/NAD+ Redox System
The effect of Walterinnesia aegyptia venom proteins on TCA cycle activity and mitochondrial NAD+-redox state in cultured human fibroblasts
Characterization of a novel thermotolerant NAD+-dependent formate dehydrogenase from hot climate plant cotton (Gossypium hirsutum L.)
Overcoming ATM deficiency by activating the NAD+/SIRT1 axis
NAD+ Cofactor Regeneration by TMB‐Mediated Horseradish‐Peroxidase‐Catalyzed Reactions
Active Site of the NAD+-Reducing Hydrogenase from Ralstonia eutropha Studied by EPR Spectroscopy
Activity of liver mitochondrial Krebs cycle NAD+-dependent dehydrogenases in rats with hepatitis induced by acetaminophen under conditions of alimentary protein …
NAD+-dependent xylitol dehydrogenase (xdhA) and l-arabitol-4-dehydrogenase (ladA) deletion mutants of Aspergillus oryzae for improved xylitol production
Schistosoma mansoni NAD+ catabolizing enzyme: Identification of key residues in catalysis
Molecular analysis of NAD+-dependent xylitol dehydrogenase from the zygomycetous fungus Rhizomucor pusillus and reversal of the coenzyme preference
Dual emission fluorescent silver nanoclusters for sensitive detection of the biological coenzyme NAD+/NADH
Extracellular β-NAD+ Inhibits Interleukin-1-Induced Matrix Metalloproteinase-1 and -3 Expression on Human Gingival Fibroblasts
Reversible redox inter-conversion of biologically active NAD+/NADH derivatives bound to a gold electrode: ToF-SIMS evidence
NAD+ replacement therapy with nicotinamide riboside does not improve cardiac function in a model of mitochondrial heart disease.
Porcine CD38 exhibits prominent secondary NAD+ cyclase activity
Synthesis and bioevaluation of aryl hydroxamates distinguishing between NAD+ and ATP-dependent DNA ligases
A paradoxical method for NAD+/NADH accumulation on an electrode surface using a hydrophobic ionic liquid
Moonlighting NAD+ Malate Dehydrogenase Is Essential for Chloroplast Biogenesis
Quantification of the metabolic heterogeneity in mycobacterial cells through the measurement of the NADH/NAD+ ratio using a genetically encoded sensor
The Development of a Biotinylated NAD+-Applied Human Poly(ADP-Ribose) Polymerase 3 (PARP3) Enzymatic Assay
Cloning, chromosomal characterization and FISH mapping of the NAD+-dependent histone deacetylase gene sirtuin 5 in the mouse
SIRT2 and Akt mediate NAD+-induced and NADH-induced increases in the intracellular ATP levels of BV2 microglia under basal conditions
High-resolution crystal structure of Streptococcus pyogenes β-NAD+ glycohydrolase in complex with its endogenous inhibitor IFS reveals a highly water-rich …
Crystal Structures of Pseudomonas aeruginosa Enoyl‐ACP Reductase (FabI) in the Presence and Absence of NAD+ and Triclosan
Colonic motor neurotransmission—is β-NAD+ in control?
Water-insoluble material from apple pomace makes changes in intracellular NAD+/NADH ratio and pyrophosphate content and stimulates fermentative production of …
Conformational Change Near the Redox Center of Dihydrolipoamide Dehydrogenase Induced by NAD+ to Regulate the Enzyme Activity
NAD+ Depletion as a cause of inflammaging
Mechanistic Studies on the pH-Controllable Hydrogenation of NAD+ by H2 and Generation of H2 from NADH by a Water-Soluble Biomimetic Iridium Complex
A new cross-linked enzyme aggregate biocatalyst for NAD+-booster production
Effect of neutral red incorporation on Al-doped ZnO thin films and its bio-electrochemical interaction with NAD+/NADP+ dependent enzymes
Structural modeling of NAD+ binding modes to PARP-1
Teasing apart NAD+ metabolism in inflammation: commentary on Zhou et al.(2016). Br J Pharmacol 173: 2352–2368.
Molecular dynamics simulation of the gGAPDH–NAD+ complex from Trypanosoma cruzi
Synthesis of a series of NAD+ analogues, potential inhibitors of PARP 1, using ADP conjugates functionalized at the terminal phosphate group
Enhancement by GOSPEL protein of GAPDH aggregation induced by nitric oxide donor and its inhibition by NAD+
NAD+ Supplementation as a Novel Approach to cURIng HCC?
Bacillus subtilis IolQ (DegA) is a transcriptional repressor of iolX encoding NAD+-dependent scyllo-inositol dehydrogenase
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.
p16INK4a, NAD+, and Sestrins: New Targets for Combating Aging‐Related Chronic Illness?
High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and …
Bienzymatic Biosensor for Malic Acid Based on Malate Dehydrogenase and Transaminase Immobilized onto a Glassy Carbon Powder/Carbon Nanotubes/NAD+ …
Decreased NAD+ in dopaminergic neurons
Nicotinamide Riboside Delivery Generates NAD+ Reserves to Protect Vascular Cells Against Oxidative Damage
In vivo 31P MRS imaging of intracellular NAD contents and NAD+/NADH redox states in normal and ischemic brains
Development of a novel enzyme-CdS nanoparticle hybrid system for the oxidation of NADH to NAD+
In vitro characterization of the NAD+ synthetase NadE1 from Herbaspirillum seropedicae
NAD+ Precursor Nicotinamide Riboside Alleviates Alcoholic Cardiomyopathy via Mitophagy Induction: A Novel SIRT3-PGAM5-FUNDC1 Axis
Oxygen-Initiated Chain Mechanism for Hydride Transfer Between NADH and NAD+ Models. Reaction of 1-Benzyl-3-Cyanoquinolinium Ion with N-Methyl-9,10 …
ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols
Computational insights into the binding modes of Sr-Rex with cofactor NADH/NAD+ and operator DNA
NAD+ Levels Control T Cell Calcium Signaling and Activation
Using Clickable NAD+ Analogs to Label Substrate Proteins of PARPs
Totally addicted to NAD+
Characterization of NADase-Inactive NAD+ Glycohydrolase in Streptococcus pyogenes
NAD+ and its precursors in human longevity
Monitoring the Sensitivity of T Cell Populations Towards NAD+ Released During Cell Preparation
Oncogene-induced NAD+ depletion in tumorigenesis
Computational model for mammalian circadian oscillator: interacting with NAD+/SIRT1 pathway and age-related changes in gene expression of circadian oscillator
The inhibition of the mitochondrial F1FO-ATPase activity when activated by Ca2+ opens new regulatory roles for NAD+
A new NAD+-dependent glyceraldehyde dehydrogenase obtained by rational design of l-lactaldehyde dehydrogenase from Escherichia coli
Cloning and characterization of a novel NAD+-dependent xylitol dehydrogenase from Gluconobacter oxydans CGMCC 1. 637.
172 Role of conserved water molecular triad in the recognition of IMP, NAD+ with Asp 274, Asn 303, Arg 322, and Asp 364 in both the isoform of hIMPDH
Transient decrease of hepatic NAD+ and amino acid alterations during treatment with valproate: new insights on drug-induced effects in vivo using targeted MS …
Nmnat1-Rbp7 is a conserved fusion-protein that combines NAD+ catalysis of Nmnat1 with subcellular localization of Rbp7
Reexamining IFN-γ stimulation of de novo NAD+ in monocyte-derived macrophages
Author Correction: Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double …
Electrochemical behavior of a Rh (pentamethylcyclopentadienyl) complex bearing an NAD+/NADH-functionalized ligand
Discovery and optimization of NAD+-dependent DNA ligase inhibitors as novel antibacterial compounds
Increasing NAD+ availability in skeletal muscle to augment energy metabolism
Characterization of hamster NAD+-dependent 3(17)β-hydroxysteroid dehydrogenase belonging to the aldo-keto reductase 1C subfamily
Redox Specificity of 2-Hydroxyacid-Coupled NAD+/NADH Dehydrogenases: A Study Exploiting “Reactive” Arginine as a Reporter of Protein Electrostatics
Inhibiting NAD+-dependent DNA ligase activity with 2-(cyclopentyloxy)-5′-deoxyadenosine (CPOdA) offers a new tool for DNA replication and repair studies in the …
Alternative NAD+ biosynthesis pathway activated by energy stress stimulates glycolysis in cardiac cells
NAD+ biosynthesis, aging, and disease
Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome …
N-Benzylnicotinamide and N-benzyl-1, 4-dihydronicotinamide: useful models for NAD+ and NADH
Characterization of glycine substitution mutations within the putative NAD+-binding site of bacillus licheniformis aldehyde dehydrogenase
Correction to The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) …
Structural Diversity of New C13-Polyketides Produced by Chaetomium mollipilium Cultivated in the Presence of a NAD+-Dependent Histone Deacetylase Inhibitor
Recent Advances in Nicotinamide Adenine Dinucluotide (NAD+) Analogs Synthesis and Their Interactions with NAD+-Dependent Enzymes
Cotton seed storage effects on vigour and activities of NAD+-dependent isocitrate dehydrogenase, malate dehydrogenase and β-amylase in seedlings
CBMT-46. MICROENVIRONMENT-DERIVED MITOCHONDRIA PRIME GLIOMA CHEMORESISTANCE BY AUGMENTING NAD+ METABOLISM AND PARP …
SIRT2, ERK and Nrf2 mediate NAD+ treatment-induced increase in the antioxidant capacity of differentiated PC12 cells under basal conditions
A new pulse sequence for single-voxel 1H MRS measurement of cerebral Nicotinamide adenine dinucleotide (NAD+) in humans at 7T using 32-channel volume coil
In vivo 31P MRS study of altered intracellular NAD content and NAD+/NADH redox state in hypoxic brain
NAD+ modulation: Biology and therapy
Regulation of Sirtuins by Systemic NAD+ Biosynthesis
Mitochondrial RNA capping: highly efficient 5′-RNA capping with NAD+ and NADH by yeast and human mitochondrial RNA polymerase
Nicotinamide Restores Tissue NAD+ and Improves Outcomes in a Murine Model of Cardiac Arrest
Promoting NAD+ production
NAD+ as a Pharmacological Tool to Boost Sirtuin Activity
The variation of NAD+-SDH gene in mutant white-fleshed loquat
Estimation of mitochondrial NADH/NAD+ ratio from FLIM
NADH/NAD+ Sensitive Protein Hyper-acetylation Links Mitochondrial Dysfunction to Cardiac Susceptibility to Stress
Extracellular NAD+ Suppresses Adrenergic Effects in the Atrial Myocardium of Rats during the Early Postnatal Ontogeny
Extension of physical endurance and protection against physical, chemical and radiological trauma by NAD+ precursors
Computational model of circadian oscillator in mammals: interaction with NAD+/SIRT1 system and age-related changes in the expression of circadian oscillator genes
Augmenting NAD+ may combat kidney stress
Renal Mitochondrial Oxidative Stress Induced by NAD+-Dependent Sirt3 Inactivation via Overexpression of CD38 (NAD+ ase) in Diabetic Kidney Disease
Nicotinamide Benzimidazolide Dinucleotides, Non-Cyclisable Analogues of NAD+
Binding mode of the oxidized α-anomer of NAD+ to RSP, a Rex-family repressor
Embryo yolk sac membrane kynurenine formamidase of l-tryptophan to NAD+ pathway as a primary target for organophosphorus insecticides (OPI) in OPI-induced …
Crystal Structure of a Hydrated Molecular 1 : 2 Complex of Nicotinamide Adenine Dinucleotide (NAD+) and Gallic Acid: Polar Alignment of the Phenolic Partner …
Efficient whole-cell biocatalyst for 2,3-butanediol/acetoin production with NADH/NAD+ regeneration system in engineered Serratia marcescens.
Alteration in substrate specificity of horse liver alcohol dehydrogenase by an acyclic nicotinamide analog of NAD+
A Novel NAD+/MWNTs Nanocomposite-Based Electrochemical Biosensor for Measuring Mevalonic Acid
Haloquadratum walsbyi Yields a Versatile, NAD+/NADP+ Dual Affinity, Thermostable, Alcohol Dehydrogenase (HwADH)
Utilizing NAD+/NADH Analogs for the Solar Fuel Forming Reductions
Covalent Immobilization of Diaphorase in Viologen Polymer Network for Highly Sensitive Detection of NAD+ and NADH
Regulation of the NAD+-dependent deacetylase SIRT2 by CDK5
Crystal structure of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase from Mesorhizobium loti
Structural Analysis of the NH3-dependent NAD+ Synthetase from Deinococcus radiodurans
Reevaluating the role of IDO1: Examining NAD+ metabolism in inflammation
Increasing specific activity of NAD+-dependent Q105R mutant of candida methylica formate dehydrogenase
The role of a peroxisomal NAD+ carrier in plants
Mechanisms of ageing metabolic decline revealed by targeted metabolomics and energy metabolism in NAD+ depleted skeletal muscle
NAD+ supplementation normalises central carbon metabolism in skeletal muscle: a mechanistic insight into the energetic consequences of age-related NAD+ decline
The Role of Nicotinamide Mononucleotide and NAMPT-Mediated NAD+ Biosynthesis in the Regulation of Age-Related Cognitive Dysfunction
THE ROLE OF MACROPHAGES IN NAD+ HOMEOSTASIS DURING AGING
Breaking NAD+: Vitamin B3 salvage and metabolism in metabolic health
Breaking NAD+: investigating NMRK2 as a regulator of muscle adaptation through NAD+ salvage
Role of ACMSD in regulation of NAD+ metabolism and mitochondrial function
EXTH-14. THE ALKYLATING CHEMOTHERAPEUTIC TEMOZOLOMIDE INDUCES METABOLIC STRESS AND POTENTIATES NAD+ DEPLETION-MEDIATED CELL …
De Novo Synthesis from Tryptophan in the Absence of a QPRTase Homolog Contributes to NAD+ Biosynthesis in C. elegans
The therapeutic role of NAD+ modulation in fatty liver disease
The Role of Nampt-Mediated NAD+ Biosynthesis in Hippocampal Neural Stem Cells and Excitatory Neurons
Exogenous NAD+ Enhances Energy Metabolism in Healthy Rat Brains
Sensitive Detection of NAD+/NADP+ via Strong Coupling Fluorescence from Silver Nanoclusters
NAD+-dependent Pathogenic Mechanisms and Metabolic Interventions for Mitochondrial Disease and its Associated Cardiomyopathy
Targeting NAD+ biosynthesis combined with radiation to enhance cell death
NAD+ salvage by Nicotinamide phosphoribosyltransferase (Nampt) mediates lipogenesis, energy homeostasis, and survival in prostate cancer
NAD+ Bound N‐terminal Domain of CARDS Toxin Increases IL‐1β Secretion
PO-463 Augmentation of NAD+ BY NQO1 activation attenuates cisplatin-mediated hearing impairment
Metabolic Interventions to Treat Mitochondrial Cardiomyopathy: Roles of NAD+ and Protein Acetylation in Leigh Syndrome
Controlling lifespan with NAD+
228P Augmentation of NAD+ by NQO1 activation attenuates cisplatin-mediated hearing impairment
Targeting NAD+ Modulating Enzymes to Improve HSC Function in Aging and Bone Marrow Failure
Direct Stimulation of Glycolysis Accounts for Cellular Metabolic Benefits of the NAD+ Precursor Nicotinamide Mononucleotide (NMN)
Abstract A33: CD38 and Nampt regulate tumor cell metabolism through modulation of NAD+
The resurgence of NAD+
ERK1/2 Regulates NAD+ Metabolism During Acute Kidney Injury Through microRNA‐34a‐Mediated NAMPT Expression
NAD+/NADH Assay Kit (Colorimetric)
Intravenous NAD+ effectively increased the NAD metabolome, reduced oxidative stress and inflammation, and increased expression of longevity genes safely in …
NAD+/NADH Assay Kit (Fluorometric)
Chemical Chaperone Activity of NAD+ in Protein Folding
Interactions of SIRT1 with Acetyl Substrate, NAD+ or Nicotinamide
Elevation of Cardiac NAD+ Levels Improves Mitochondrial Function in Mice Lacking Sirtuin 3
Insight into enzymes which synthesize and metabolize NAD+ and new NAD+ prodrugs
NAD+ availability modulates 11 [beta]-HSD1 mediated glucocorticoid regeneration in mouse skeletal muscle
Investigation of the Ionization Mechanism of NAD+/NADH-Modified Gold Electrodes in ToF-SIMS Analysis
The Role of GPR109A in NAD+ Metabolism in Aging RPE
Nicotinamide riboside and cellular NAD+ redox state influence 11 [beta]-HSD1 mediated glucocorticoid regeneration in skeletal muscle cells
The nicotinamide phosphoribosyltransferase (NAMPT)-mediated NAD+ biosynthetic pathway is essential for photoreceptor survival and vision
NADH→NAD+ Transhydrogenation in Adult Ascaris suum Mitochondria
Disruption of the NAD+-binding site affects GAPDH interactions in the nuclei of cancer cells outside glucose metabolism
Modulation of innate immune cells by the NAD+ pathway
IMPAIRMENT OF AN ENDOTHELIAL NAD+-H2S SIGNALING NETWORK IS A REVERSIBLE CAUSE OF VASCULAR AGING
An overview of the ferredoxin NAD+ reductases used for energy conservation in various anaerobic microorganisms
Elucidation of the Developmental and Physiological Roles of NAD+ Biosynthetic Pathways
Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells
Monomethylfumarate induces NAD+ and SIRT1 in Human Retinal Pigment Epithelial Cells: Relevance to Development of New Therapies for Dry AMD
Reply to Moon and Minhas: Teasing apart NAD+ metabolism in inflammation: commentary on Zhou et al.(2016). Br J Pharmacol 173: 2352–2368
Exploiting tumor vulnerabilities: NAD+-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies
Raising cellular NAD+ levels in human cells by nicotinic acid supplementation: biological consequences related to PARP-1 mediated reactions
Cytoplastic NAD+ biosynthesis affects gonad development in Caenorhabditis elegans
NAD+ Metabolism in Neurodegeneration and Ageing
Pathologic poly (ADP-ribose) polymerase (PARP) activation contributes to retinal degeneration in mice with retinal NAD+ deficiency
Nicotinamide adenine dinucleotide hydrate (NAD+) regulates glucose deprivation‐induced activation of protein O‐GlcNAcylation, ER stress and autophagy (1154.2)
Novel NAD+ metabolomic technologies and their applications to nicotinamide riboside interventions
Physiological Effects of Modulating Sirtuin 5 and Mitochondrial NAD+ Biosynthesis in Mammals
SIMULTANEOUS DETERMINATION OF ATP, ITS METABOLITES AND NAD+ IN BLOOD BY HPLC WITH PHOTODIODE ARRAY DETECTOR
Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human
Mitochondrial complex I modulation of cellular NAD+/NADH regulates mTOR, autophagy and breast cancer progression
PO-251 Modulation of NAD+ levels by NQO1 enzymatic action alleviates adriamycin-induced cardiac dysfunction in mice
Production of 2, 3-Butanediol by NAD+/NADH Ratio Change
Genetically Encoded Tools for Compartment-Specific Manipulation of NAD+/NADH or NADP+/NADPH Ratios
Identification of activation of tryptophan‐NAD+ pathway as a central metabolic response to chemical stress from feeding thermally‐oxidized soybean oil in mouse …
PARP Activation, NAD+ Depletion, and Energy Dysregulation following Traumatic Brain Injury
Augmentation of NAD+ levels by enzymatic action of NAD (P) H quinone oxidoreductase 1 attenuates adriamycin-induced cardiomyopathy
Investigation of the NADH/NAD+ state in Ralstonia eutropha H16 using the fluorescence reporter protein Peredox and Synthesis strategies of RNase A by …
Nicotinic Acid Protects Against Abdominal Aortic Aneurysm Formation via GPR109A Receptor-Independent Mechanisms: Role of NAD+
Production and molecular characterization of NAD+ related enzymes and their advanced intermediates
The [NAD+ over Sirtuin] Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Clickable chain terminator NAD+ analogs for labeling substrate proteins of poly(ADP-ribose) polymerases
CD38 Deregulation As Strategy to Make Multiple Myeloma Cells More Sensitive to NAD+ Depleting Agents
Glutamine modulates cellular NAD+/NADH homeostasis thereby regulating cancer metastasis, drug sensitivity in cancer cells
560 NAD+ Regeneration in Smooth Muscle Cells is Required to Maintain Vascular Integrity During Angiotensin II-Mediated Stress
NAMPT/NAD+/SIRT1-Triggered Deacetylation Of Hematopoietic Cell-Specific Lyn-Substrate 1 (HCLS1) In Congenital Neutropenia
O-GlcNAcylation regulates breast cancer cell invasion via the NAD+-dependent deacetylase SIRT1
Metabolomic Profiling Reveals Up-regulated Glycolysis (Warburg Effect) and Increased NAD+ Biosynthesis in ER-Breast Cancers From African American Women
PARP1 inhibition attenuates NAD+ depletion and protects against experimental and human Atrial Fibrillation
PO-028 Effective targeting of NAD+ biosynthesis in patient-derived xenograft models of high-risk paediatric acute lymphoblastic leukaemia
The Role of the Clock-NAD+ Feedback Loop in Metabolic Pathophysiology
Nicotinamide riboside as a new vitamin B3 and studies on NAD+ signaling
Purification, Crystallization, and X-ray Crystallographic Studies on Bacillus cereus 3-Hydroxyisobutyrate Dehydrogenase and Its Complex with NAD+
Tissue specific effects of NAD+ biosynthesis on muscle function, fat metabolism and gonad development in Caenorhabditis elegans
for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
NAD+ Kinase inhibition synergizes with ROS-inducing chemotherapies.
… STRESS AND TARGETING CELLULAR STRESS RESPONSE BY INHIBITION OF NAMPT, THE RATE LIMITING ENZYME IN THE NAD+ SALVAGE PATHWAY IN …
Imaging of Nicotinamide adenine dinucleotide (NAD+) in vitro using CEST
In Vivo Assessment of Intracellular NAD+/NADH Redox State in Human Brain at 4 Tesla
Intracellular NAD+ Depletion Enhances Bortezomib-Induced Myeloma Cytotoxicity
The G308E variant of the apoptosis inducing factor, responsible of a rare encephalopathy, is hampered in NAD+/H binding
Observing the dynamics of the NAD+ to NADH ratio in Danio rerio embryo tissues using a genetically encoded biosensor
The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division
HEMATOPOIETIC-SPECIFIC LYN-SUBSTRATE 1 (HCLS) IS DEACETYLAT-ED BY NAMPT/NAD+/SIRT1 PATHWAY
Modulation of Sirtuin NAD+‐dependent Deacylase Activity by Cysteine Oxidation
Exogenous pyruvate supports oxygen-independent tumor cell proliferation by serving as an oxygen surrogate to maintain homeostasis of NAD+/NADH
Nicotinamide dinucleotide (NAD+)-boosting strategies in aging and metabolic disease
… -Ptr3-Ssy5 (SPS) Signaling Pathway Extends Replicative Life Span by Enhancing Nicotinamide Adenine Dinucleotide (NAD+) Homeostasis and Phosphate …
Hematopoietic-specific lyn-substrate 1 (HCLS) is deacetylated by NAMPT/NAD+/SIRT1 pathway
Making sense of NAD+ subcellular localization
Microenvironment-derived mitochondria prime glioma chemoresistance by augmenting NAD+metabolism and PARP-dependent DNA repair
Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site,” selectivity pocket” and NAD+-binding site
Glycerol Oxidation By NAD+-Dependent Enzymatic Systems
ºese are N6-(6-aminohexyl)-AMP, 8–(6-aminohexyl)-amino-cyclic AMP, N-carboxymethyl-NAD* and NAD+-nº-(N-(6-aminohexyl)-acetamidej.
Synthesis and Characterisation of NAD+ Analogues for the Cellular Imaging of Poly(ADP-Ribos)ylation
COMPUTATIONAL MODEL FOR MAMMALIAN CIRCADIAN OSCILLATOR INTERACTING WITH NAD+/SIRT1 PATHWAY
Processable and anti-NAD+ fouling colloidal PEDOT microparticles based hierarchical structured interface with enhanced electrode kinetics for sensitive NADH …
Correction to: ADP-ribosylation and NAD+ Utilizing Enzymes
Purification of NAD+ glycohydrolase from human serum
Change in NAD+/NADH Content of S-Adenosyl-L-Homocysteine Hydrolase upon NAD” Reversible
… of Two Site-Specific Mutations in Human Dihydrolipoamide Dehydrogenase Deteriorating the Apparent Enzyme Binding Affinities to Both Dihydrolipoamide and NAD+
EXTH-84. TARGETING THE SALVAGE PATHWAY OF NAD+ GENERATION IN GLIOMAS BY KPT-9274, A NOVEL DUAL INHIBITOR OF PAK4 AND NAMPT
Involvement of mitochondrial NAD+-dependent deacetylase Sirt3 in the regulation of myoblast differentiation
1P028 Analysis of structural change of L-threonine dehydrogenase from Cupriavidus necator (CnThrDH) by binding of L-Thr and NAD+ (Protein: Structure & Function …
Phenformin inhibits proliferation of acquired gefitinib resistant non‐small‐cell lung cancer(NSCLC) through the reduction of NAD+/NADH ratio
Author Correction: Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis
Lubiprostone (a prostone) slows the in vitro growth of colon adenosarcoma cells with low [NAD+] 15‐OH PGDH (LB856)
Nicotinamide Riboside, an NAD+ Precursor, Attenuates The Activation of Hepatic Stellate Cells
The NAD+-Dependent Histone Deacetylase Sirtuin-2 is Upregulated during Myogenesis and Promotes the Differentiation of C2C12 Myoblasts
Synthesis and the Stimuli‐Responsive Characteristics of Cyclic Cholamide Nicotinamide Adenine Dinucleotide (NAD+) Derivative with Aggregation in Basic Aqueous …
Regulation of the Mitogen Activated Protein Kinase Kinase (MEK)-1 by NAD+-Dependent Deacetylases
Metabolic conversions of NAD+ and cyclic ADP
Identification of a novel NAMPT inhibition resistance mechanism utilizing the de novo NAD+ biosynthesis pathway
The Rice NAD+-Dependent Histone Deacetylase OsSRT1 Targets Preferentially to Stress-and
Benzophenones from an Endophytic Fungus, Graphiopsis chlorocephala, from Paeonia lactiflora Cultivated in the Presence of an NAD+-Dependent HDAC Inhibitor
NAD+-Dependent Deacetylases and Medical Therapy
obtained by copolymerization of NAD+ derivative A and acrylamide.
Methanol/Oxygen Enzymatic Biofuel Cell Using Laccase and NAD+-Dependent Dehydrogenase Cascades as Biocatalysts on Carbon Nanodots Electrodes
Active Site of the NAD+-Reducing Hydrogenase from Ralstonia eutropha Studied by EPR Spectroscopy
Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome …
NAD+ as a Hydride Donor and Reductant
Rhodium-Coordinated poly (arylene-ethynylene)-alt-Poly (arylene-vinylene) Copolymer as Photocatalyst for Visible-Light-Powered NAD+/NADH Reduction
Efficient Catalytic Interconversion between NADH and NAD+ Accompanied by Generation and Consumption of Hydrogen with a Water-Soluble Iridium Complex at …
The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells…
Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD+/H Binding to Mitochondrial Apoptosis-Inducing Factor
A unique NAD+ phosphorylase toxin triggers bacterial suicide in Mycobacterium tuberculosis
The NAD+-dependent histone deacetylase
Correction: Redox Specificity of 2-Hydroxyacid-Coupled NAD+/NADH Dehydrogenases: A Study Exploiting “Reactive” Arginine as a Reporter of Protein Electrostatics
Cover Picture: Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD+, NADPH, or NAD+/10‐Oxogeranial: Reaction Mechanisms (Angew …
Impact of the Iron–Sulfur Cluster Proximal to the Active Site on the Catalytic Function of an O2-Tolerant NAD+-Reducing [NiFe]-Hydrogenase
Photocatalytic Reductions using p-GaP Photoelectrode and NAD+/NADH Analogs
Hydrogen Evolution from Aliphatic Alcohols and 1, 4-Selective Hydrogenation of NAD+ Catalyzed by a [C, N] and a [C, C] Cyclometalated Organoiridium Complex at …
Nampt-Mediated NAD+ Homeostasis in Skeletal Muscle: Implications for Healthy Aging
Reversible Active Site Sulfoxygenation Can Explain the Oxygen Tolerance of a NAD+-Reducing [NiFe] Hydrogenase and Its Unusual Infrared Spectroscopic …
Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD+ and Fluoroalcohols Define Strained Michaelis Complexes
Reversible Protein Acetylation in the Mitochondria: Cellular and Molecular Function of the NAD+ Dependent Deacetylase Sirtuin 3
Rhodium-Coordinated Poly (arylene-ethynylene)-alt-Poly (arylene-vinylene) Copolymer Acting as Photocatalyst for Visible-Light-Powered NAD+/NADH Reduction
to be NAD+ dependent. The presence of 15-hydroxyprostaglandin de
Investigation of NADH Binding, Hydride Transfer, and NAD+ Dissociation during NADH Oxidation by Mitochondrial Complex I Using Modified Nicotinamide …
NT-33 NAD+ SYNTHESIS INHIBITION AS A THERAPEUTIC STRATEGY FOR GLIOBLASTOMA WITH MYC AMPLIFICATION
NADH→ NAD+ Transhydrogenation in Adult Ascaris suum Mitochondria
NAD+-Dependent SIRT1 Reprograms CD11c+ Dendritic Cells and Cd4+ T Cells to Control Immune Polarity During Sepsis
Oxygen-Initiated Chain Mechanism for Hydride Transfer Between NADH and NAD+ Models. Reaction of 1-Benzyl-3-Cyanoquinolinium Ion with N-Methyl-9, 10 …
Monocyte-derived Extracellular Nampt-dependent Biosynthesis of Myocardial NAD+ Protects the Heart against Pressure Overload
EFFECTS OF GARLIC EXTRACT ON NAD+ DEPENDENT HISTONE DEACETYLASES IN DIABETIC RATS
The role of mitochondrial NAD+-dependent SIRT3 deacetylase during chronic pain
Cloning and over-expression of NAD+-dependent xylitol dehydrogenase (XDH) in thermotolerant Gluconobacter frateurii THD32
Vesicle Encapsulation of a Nonbiological Photochemical System Capable of Reducing NAD+ to NADH
Computational Simulation of Solution Phase NADH/NAD + Model Reactions
Visfatin is involved in TNFα-mediated insulin resistance via an NAD+/Sirt1/PTP1B pathway in 3T3-L1 adipocytes
NAD+ Glucose+ Pi+ NADP+ 2C. H. Oh+ 2CO, 2
Coupling NAD+ regeneration with overexpression of key enzymes for 3-hydroxypropionic acid biosynthesis in Klebsiella pneumoniae
NAD+ metabolism and its roles in cellular processes during ageing
NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential
NAD+ homeostasis in health and disease
SLC25A51 is a mammalian mitochondrial NAD+ transporter
Niacin cures systemic NAD+ deficiency and improves muscle performance in adult-onset mitochondrial myopathy
Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation
NAD+ metabolism, stemness, the immune response, and cancer
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels
NAD+ metabolism governs the proinflammatory senescence-associated secretome
NAD+ cleavage activity by animal and plant TIR domains in cell death pathways
Role of NAD+ in regulating cellular and metabolic signaling pathways
NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING
NAD+ in COVID-19 and viral infections
The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1
NAD+ in brain aging and neurodegenerative disorders
NAD+ homeostasis in human health and disease
Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage
Interplay between compartmentalized NAD+ synthesis and consumption: a focus on the PARP family
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
NAD+ homeostasis in renal health and disease
TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death
NAD+ metabolism maintains inducible PD-L1 expression to drive tumor immune evasion
NAD+ repletion rescues female fertility during reproductive aging
NAD+ Metabolism in Cardiac Health, Aging, and Disease
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor
Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan
Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction
Age-related NAD+ decline
Location, location, location: compartmentalization of NAD+ synthesis and functions in mammalian cells
Nicotinamide mononucleotide: a promising molecule for therapy of diverse diseases by targeting NAD+ metabolism
NAD+ controls circadian reprogramming through PER2 nuclear translocation to counter aging
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity
The Plasma NAD+ Metabolome Is Dysregulated in “Normal” Aging
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo
COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity
A phytobacterial TIR domain effector manipulates NAD+ to promote virulence
Illuminating NAD+ metabolism in live cells and in vivo using a genetically encoded fluorescent sensor
Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities
NRH salvage and conversion to NAD+ requires NRH kinase activity by adenosine kinase
Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice
Healthy aging and muscle function are positively associated with NAD+ abundance in humans
Role of endothelial NAD+ deficiency in age-related vascular dysfunction
NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis
NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral …
The balance between NAD+ biosynthesis and consumption in ageing
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration
Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease
Evolving concepts in NAD+ metabolism
The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline
… cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of …
In planta study of photosynthesis and photorespiration using NADPH and NADH/NAD+ fluorescent protein sensors
NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
Increasing ovarian NAD+ levels improve mitochondrial functions and reverse ovarian aging
NAD+-capped RNAs are widespread in the Arabidopsis transcriptome and can probably be translated
Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models
Boosting NAD+ with a small molecule that activates NAMPT
The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease
CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD+/NADH ratio and Sirt3 activity in renal …
Subcellular compartmentalization of NAD+ and its role in cancer: A sereNADe of metabolic melodies
Polyunsaturated fatty acid desaturation is a mechanism for glycolytic NAD+ recycling
A pilot study investigating changes in the human plasma and urine NAD+ metabolome during a 6 hour intravenous infusion of NAD+
NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
NAD+ metabolism as a target for metabolic health: have we found the silver bullet?
Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models
NAD+ regeneration rescues lifespan, but not ataxia, in a mouse model of brain mitochondrial complex I dysfunction
Regulation of NAD+ metabolism in aging and disease
NAD+ Metabolism and Regulation: Lessons From Yeast
Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease
Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells
Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion
Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD+ and SIRT1
NAD+ Deficiency Is a Common Central Pathological Factor of a Number of Diseases and Aging: Mechanisms and Therapeutic Implications
Nicotinamide adenine dinucleotide (NAD+): essential redox metabolite, co-substrate and an anti-cancer and anti-ageing therapeutic target
DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation
Messenger RNA 5′ NAD+ capping is a dynamic regulatory epitranscriptome mark that is required for proper response to abscisic acid in Arabidopsis
Mitochondrial NAD+/NADH Redox State and Diabetic Cardiomyopathy
Age-dependent decline of NAD+—universal truth or confounded consensus?
NAD+ supplementation rejuvenates aged gut adult stem cells
eNAMPT actions through nucleus accumbens NAD+/SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress
… of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide‐induced microglial and astrocytic neuroinflammation by increasing NAD+
Regulation of Glucose Metabolism by NAD+ and ADP-Ribosylation
The taming of PARP1 and its impact on NAD+ metabolism
Aberrant NAD+ metabolism underlies Zika virus–induced microcephaly
Structural and functional evidence of bacterial antiphage protection by Thoeris defense system via NAD+ degradation
A biosensor for measuring NAD+ levels at the point of care
NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy
NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin
… ) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor CellsSequestration of NAD+ in …
Aerobic and resistance exercise training reverses age‐dependent decline in NAD+ salvage capacity in human skeletal muscle
NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging
Mitophagy and NAD+ inhibit Alzheimer disease
A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes
NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro
miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD+/SIRT inactivation
NAD+ precursor modulates post-ischemic mitochondrial fragmentation and reactive oxygen species generation via SIRT3 dependent mechanisms
Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD+ Synthesis During Inflammation and Infection
Resistance training increases muscle NAD+ and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight …
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux
Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy
NAD+ Metabolism and Diseases with Motor Dysfunction
Combined cross-linked enzyme aggregates of glycerol dehydrogenase and NADH oxidase for high efficiency in situ NAD+ regeneration
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing
Role of mitochondria in diabetic peripheral neuropathy: Influencing the NAD+-dependent SIRT1–PGC-1α–TFAM pathway
Mitochondrial NAD+ controls nuclear ARTD1-induced ADP-ribosylation
A systems-approach to NAD+ restoration
Influence of NAD+ as an ageing-related immunomodulator on COVID 19 infection: A hypothesis
The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
NAD+ consumption by PARP1 in response to DNA damage triggers metabolic shift critical for damaged cell survival
The significance of NAD+ metabolites and nicotinamide N-methyltransferase in chronic kidney disease
Mitochondrial translation deficiency impairs NAD+‐mediated lysosomal acidification
Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis
Polymer‐Based Module for NAD+ Regeneration with Visible Light
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance
The Key Role of NAD+ in Anti-Tumor Immune Response: An Update
Effects of NAD+ precursor supplementation on glucose and lipid metabolism in humans: a meta-analysis
Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes
Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
Dihydronicotinamide riboside is a potent NAD+ precursor promoting a pro-inflammatory phenotype in macrophages
NAD+ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging
NAD+ metabolism regulates preadipocyte differentiation by enhancing α-ketoglutarate-mediated histone H3K9 demethylation at the PPARγ promoter
NMNAT2‐mediated NAD+ generation is essential for quality control of aged oocytes
Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis–like phenotypes
Implications of NAD+ boosters in translational medicine
NAD+ and NAFLD – caution, causality and careful optimism
Implications of NAD+ metabolism in the aging retina and retinal degeneration
Nicotinamide riboside, an NAD+ precursor, attenuates inflammation and oxidative stress by activating sirtuin 1 in alcohol-stimulated macrophages
Coordinated metabolic transitions and gene expression by NAD+ during adipogenesis
Cellular Compartmentation and the Redox/Nonredox Functions of NAD+
Notoginsenoside R1 activates the NAMPT-NAD+-SIRT1 cascade to promote postischemic angiogenesis by modulating Notch signaling
Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD+–Sirt1 signaling
The mitochondrial NAD+ transporter (NDT1) plays important roles in cellular NAD+ homeostasis in Arabidopsis thaliana
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway
Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox
NAD+ Metabolism, Metabolic Stress, and Infection
Role of the global regulator Rex in control of NAD+‐regeneration in Clostridioides (Clostridium) difficile
Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity
NAD+ Therapeutics and Skeletal Muscle Adaptation to Exercise in Humans
Assessment of NAD+ metabolism in human cell cultures, erythrocytes, cerebrospinal fluid and primate skeletal muscle
NADH/NAD+ Redox Imbalance and Diabetic Kidney Disease
The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila
Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity
Nicotinamide Riboside and Dihydronicotinic Acid Riboside Synergistically Increase Intracellular NAD+ by Generating Dihydronicotinamide Riboside
An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death
Mitochondrial PARP1 regulates NAD+-dependent poly ADP-ribosylation of mitochondrial nucleoids
NAD+ Metabolism in Aging and Cancer
Use of NAD tagSeq II to identify growth phase-dependent alterations in E. coli RNA NAD+ capping
The tuberculosis necrotizing toxin is an NAD+ and NADP+ glycohydrolase with distinct enzymatic properties
In Vivo NADH/NAD+ Biosensing Reveals the Dynamics of Cytosolic Redox Metabolism in Plants
Improving the production of NAD+ via multi-strategy metabolic engineering in Escherichia coli
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis
NAMPT reduction‐induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice
Multiomics analysis of the NAD+–PARP1 axis reveals a role for site-specific ADP-ribosylation in splicing in embryonic stem cells
BMAL1 drives muscle repair through control of hypoxic NAD+ regeneration in satellite cells
Niacin: an old lipid drug in a new NAD+ dress
Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice
SPAAC-NAD-seq, a sensitive and accurate method to profile NAD+-capped transcripts
Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7-Oxo-lithocholic Acid
The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions
Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled …
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ …
Degradation of Extracellular NAD+ Intermediates in Cultures of Human HEK293 Cells
Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells …
Effect of NAD+ boosting on kidney ischemia-reperfusion injury
Impaired nicotinamide adenine dinucleotide (NAD+) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
NAD+ metabolism in peripheral neuropathic pain
Role of PGC-1α in the Mitochondrial NAD+ Pool in Metabolic Diseases
Sex‐specific alterations in NAD+ metabolism in 3xTg Alzheimer’s disease mouse brain assessed by quantitative targeted LC‐MS
Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD+ depletion
Chemoselective NADH Regeneration: the Synergy Effect of TiOx and Pt in NAD+ Hydrogenation
NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis
NAD+-consuming enzymes in immune defense against viral infection
Adipose tissue NAD+ biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice
Global metabolic shifts in age and Alzheimer’s disease mouse brains pivot at NAD+/NADH redox sites
Therapeutic potential of emerging NAD+-increasing strategies for cardiovascular diseases
Listeria monocytogenes requires cellular respiration for NAD+ regeneration and pathogenesis
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death
Acute sources of mitochondrial NAD+ during respiratory chain dysfunction
Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis
Attenuates of NAD+ impair BMSC osteogenesis and fracture repair through OXPHOS
Balancing NAD+ deficits with nicotinamide riboside: therapeutic possibilities and limitations
NADH Regeneration: A Case Study of Pt-Catalyzed NAD+ Reduction with H2
Mitochondrial transport and metabolism of the vitamin B‐derived cofactors thiamine pyrophosphate, coenzyme A, FAD and NAD+, and related diseases: A review
A Method to Monitor the NAD+ Metabolome—From Mechanistic to Clinical Applications
Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome
Local Targeting of NAD+ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma
Interacting NAD+ and Cell Senescence Pathways Complicate Antiaging Therapies
Efficient production of androstenedione by repeated batch fermentation in waste cooking oil media through regulating NAD+/NADH ratio and strengthening cell vitality …
Rapamycin maintains NAD+/NADH redox homeostasis in muscle cells
CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD+/Sirt1 Signaling Pathway
Potential of polyphenols to restore SIRT1 and NAD+ metabolism in renal disease
A second riboswitch class for the enzyme cofactor NAD+
PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide
Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD+ and Suppresses Glycolysis, the TCA Cycle, and Cell Growth
A Bifunctional NAD+ for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins
Evidence that the nadA motif is a bacterial riboswitch for the ubiquitous enzyme cofactor NAD+
The Molecular Story of COVID-19; NAD+ Depletion Addresses All Questions in this Infection
Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level
Welcome to the Family: Identification of the NAD+ Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25
The RES domain toxins of RES‐Xre toxin‐antitoxin modules induce cell stasis by degrading NAD+
A regulatory NADH/NAD+ redox biosensor for bacteria
NAD+ and cardiovascular diseases
Mono(ADP-ribosyl)ation Enzymes and NAD+ Metabolism: A Focus on Diseases and Therapeutic Perspectives
NAD+ precursors protect corneal endothelial cells from UVB-induced apoptosis
Benefits in cardiac function by CD38 suppression: Improvement in NAD+ levels, exercise capacity, heart rate variability and protection against catecholamine-induced …
Supplementation with NAD+ and Its Precursors to Prevent Cognitive Decline across Disease Contexts
NAD+ augmentation with nicotinamide riboside improves lymphoid potential of Atm−/− and old mice HSCs
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic β Cells Due to Decreasing Mitochondrial Matrix NADH/NAD+ …
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus
FGF21 promotes ischaemic angiogenesis and endothelial progenitor cells function under diabetic conditions in an AMPK/NAD+‐dependent manner
Cell stress response impairs de novo NAD+ biosynthesis in the kidney
Activation of cardiac Nmnat/NAD+/SIR2 pathways mediates endurance exercise resistance to lipotoxic cardiomyopathy in aging Drosophila
NAD+ ameliorates endotoxin‐induced acute kidney injury in a sirtuin1–dependent manner via GSK‐3β/Nrf2 signalling pathway
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling
A phase transition enhances the catalytic activity of SARM1, an NAD+ glycohydrolase involved in neurodegeneration
Exogenous NAD+ Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 Signaling
Muscle NAD+ depletion and Serpina3n as molecular determinants of murine cancer cachexia—The effects of blocking myostatin and activins
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
Dual control of NAD+ synthesis by purine metabolites in yeast
Codonopsis pilosula polysaccharides alleviate Aβ1-40-induced PC12 cells energy dysmetabolism via CD38/NAD+ signaling pathway
Neuroprotection in Glaucoma: NAD+/NADH Redox State as a Potential Biomarker and Therapeutic Target
Targeting Nuclear NAD+ Synthesis Inhibits DNA Repair, Impairs Metabolic Adaptation and Increases Chemosensitivity of U-2OS Osteosarcoma Cells
Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding
The challenges of using NAD+-dependent formate dehydrogenases for CO2 conversion
A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation
NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Bioactive NAD+ Regeneration Promoted by Multimetallic Nanoparticles Based on Graphene–Polymer Nanolayers
Structure and ligand binding of the ADP-binding domain of the NAD+ riboswitch
Viral infection as an NAD+ battlefield
Crocin ameliorates depressive-like behaviors induced by chronic restraint stress via the NAMPT-NAD+-SIRT1 pathway in mice
A Combination of Nicotinamide and D-Ribose (RiaGev) Is Safe and Effective to Increase NAD+ Metabolome in Healthy Middle-Aged Adults: A Randomized, Triple …
The development of NAD+-dependent dehydrogenase screen-printed biosensor based on enzyme and nanoporous gold co-catalytic strategy
Circadian transcription factor NPAS2 and the NAD+‐dependent deacetylase SIRT1 interact in the mouse nucleus accumbens and regulate reward
Mutant Nmnat1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal …
NAD+ deficiency and mitochondrial dysfunction in granulosa cells of women with polycystic ovary syndrome
NAMPT-dependent NAD+ salvage is crucial for the decision between apoptotic and necrotic cell death under oxidative stress
MiR-34a suppression targets Nampt to ameliorate bone marrow mesenchymal stem cell senescence by regulating NAD+-Sirt1 pathway
Sobriety and satiety: is NAD+ the answer?
Construction of an Alternative NAD+ De Novo Biosynthesis Pathway
Advantages of formate dehydrogenase reaction for efficient NAD+ quantification in biological samples
Rapid Entrapment of Phenazine Ethosulfate within a Polyelectrolyte Complex on Electrodes for Efficient NAD+ Regeneration in Mediated NAD+-Dependent …
Screen-Printed Carbon Electrodes Modified with Graphene Oxide for the Design of a Reagent-Free NAD+-Dependent Biosensor Array
PGC-1α, sirtuins and PARPs in Huntington’s disease and other neurodegenerative conditions: NAD+ to rule them all
Single‐Voxel 1H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD+) in humans at 7T using a 32‐channel volume coil
IFNγ regulates NAD+ metabolism to promote the respiratory burst in human monocytes
Augmentation of cellular NAD+ by NQO1 enzymatic action improves age‐related hearing impairment
Genetically encoded biosensors for evaluating NAD+/NADH ratio in cytosolic and mitochondrial compartments
ZnO Materials as Effective Anodes for the Photoelectrochemical Regeneration of Enzymatically Active NAD+
Low NAD+ levels are associated with a decline of spermatogenesis in transgenic ANDY and aging mice
Hepatic DNA damage induced by electronic cigarette exposure is associated with the modulation of NAD+/PARP1/SIRT1 axis
Antiplatelet Effect of Carbon Monoxide Is Mediated by NAD+ and ATP Depletion
NAD+‐Dependent Enzymatic Route for the Epimerization of Hydroxysteroids
Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity
Healthy Lifestyle Recommendations: Do the Beneficial Effects Originate from NAD+ Amount at the Cellular Level?
Targeting NAD+ metabolism to enhance radiation therapy responses
Ex Vivo Lung Perfusion with β-Nicotinamide Adenine Dinucleotide (NAD+) Improves Ischemic Lung Function
Modulation of NAD+ biosynthesis activates SIRT1 and resists cisplatin-induced ototoxicity
Phenothiazine normalizes the NADH/NAD+ ratio, maintains mitochondrial integrity and protects the nigrostriatal dopamine system in a chronic rotenone …
NAD+ Modulates the Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells via Akt Signaling Pathway
The role of the tryptophan-NAD+ pathway in a mouse model of severe malnutrition induced liver dysfunction
NAD+ salvage governs mitochondrial metabolism, invigorating natural killer cell antitumor immunity
Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau
Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases
HKUST-1 catalyzed efficient in situ regeneration of NAD+ for dehydrogenase mediated oxidation
The catalytic mechanism of electron-bifurcating electron transfer flavoproteins (ETFs) involves an intermediary complex with NAD+
NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in …
ddhCTP produced by the radical‐SAM activity of RSAD2 (viperin) inhibits the NAD+‐dependent activity of enzymes to modulate metabolism
Tungsten Enzyme Using Hydrogen as an Electron Donor to Reduce Carboxylic Acids and NAD+
NAD+ cellular redox and SIRT1 regulate the diurnal rhythms of tyrosine hydroxylase and conditioned cocaine reward
CD38 deficiency protects mice from high fat diet-induced nonalcoholic fatty liver disease through activating NAD+/sirtuins signaling pathways-mediated …
Apigenin Alleviates Oxidative Stress-Induced Cellular Senescence via Modulation of the SIRT1-NAD-CD38 Axis
NAD+ Metabolism as an Emerging Therapeutic Target for Cardiovascular Diseases Associated With Sudden Cardiac Death
Molecular properties and regulation of NAD+ kinase (NADK)
NAD+ regeneration drives cancer cell proliferation
NAD+ and vascular dysfunction: from mechanisms to therapeutic opportunities
NAD+ in Alzheimer’s Disease: Molecular Mechanisms and Systematic Therapeutic Evidence Obtained in vivo
NAD+-mediated regulation of mammalian base excision repair
Specific Binding of snoRNAs to PARP-1 Promotes NAD+-Dependent Catalytic Activation
Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioavailability and attenuated cardiac ischemia/reperfusion injury in …
Human DNA ligase IV is able to use NAD+ as an alternative adenylation donor for DNA ends ligation
Host NAD+ metabolism and infections: therapeutic implications
Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome
Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA-and UVB-irradiated epidermal keratinocytes
NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells
Protometabolic Reduction of NAD+ with α-Keto Acids
An NAD+-dependent deacetylase SIRT7 promotes HCC development through deacetylation of USP39
SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure
Role of geochemical protoenzymes (geozymes) in primordial metabolism: specific abiotic hydride transfer by metals to the biological redox cofactor NAD+
Unexpected Photocatalytic Degeneration of NAD+ for Inducing Apoptosis of Hypoxia Cancer Cells
Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD+ Hydrolase Activity of CD38-Expressing Multiple Myeloma …
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function
Sirtuin 3 Dependent and Independent Effects of NAD+ to Suppress Vascular Inflammation and Improve Endothelial Function in Mice
Aryl hydrocarbon receptor (AHR) functions in NAD+ metabolism, myelopoiesis and obesity
Scalable syntheses of traceable ribosylated NAD+ precursors
NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity
Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT–NAD+–SIRT1 pathway
Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice
NAD+ flux is maintained in aged mice despite lower tissue concentrations
The Ralstonia solanacearum effector RipN suppresses plant PAMP‐triggered immunity, localizes to the endoplasmic reticulum and nucleus, and alters the NADH/NAD+ ratio in …
ORP control for boosting ethanol productivity in gas fermentation systems and dynamics of redox cofactor NADH/NAD+ under oxidative stress
Regulation of Cancer and Cancer-Related Genes via NAD+
Influence of electrode potential, pH and NAD+ concentration on the electrochemical NADH regeneration
Regulation of mitochondrial NAD pool via NAD+ transporter 2 is essential for matrix NADH homeostasis and ROS production in Arabidopsis
… enables mediator-free and low-overpotential electrochemical oxidation of NADH: A facile method for the development of an NAD+-dependent enzyme biosensor
Spatiotemporal monitoring of NAD+ metabolism with fluorescent biosensors
Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis
CD38 downregulation modulates NAD+ and NADP (H) levels in thermogenic adipose tissues
Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD+-mediated mitonuclear communication through PGC1α/PPARγ …
NAD+, Senolytics, or Pyruvate for Healthy Aging?
NAD+ depletion and defense in bacteria
Modulation of the cardiac sodium channel NaV1. 5 peak and late currents by NAD+ precursors
Subcellular NAMPT‐mediated NAD+ salvage pathways and their roles in bioenergetics and neuronal protection after ischemic injury
Alterations in kynurenine and NAD+ salvage pathways during the successful treatment of inflammatory bowel disease suggest HCAR3 and NNMT as potential …
Reduced nuclear NAD+ drives DNA damage and subsequent immune activation in the retina
Harnessing NAD+ Metabolism as Therapy for Cardiometabolic Diseases
NAD+ repletion attenuates obesity‐induced oocyte mitochondrial dysfunction and offspring metabolic abnormalities via a SIRT3‐dependent pathway
Exogenous supplemental NAD+ protect myocardium against myocardial ischemic/reperfusion injury in swine model
NAD+‐targeting by bacteria: an emerging weapon in pathogenesis
NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
NAD+ deficiency in human congenital malformations and miscarriage: A new model of pleiotropy
… stress directly induces bone formation by activating glucose transporter 1 (GLUT 1) in osteoblasts, inducing signaling via NAD+-dependent deacetylase (Sirtuin 1) …
Soluble adenylyl cyclase regulates the cytosolic NADH/NAD+ redox state and the bioenergetic switch between glycolysis and oxidative phosphorylation
Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice
Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron …
NAD+ metabolism and retinal degeneration
Palmitic Acid-Induced NAD+ Depletion is Associated with the Reduced Function of SIRT1 and Increased Expression of BACE1 in Hippocampal Neurons
Inhibition of NAD kinase elevates the hepatic NAD+ pool and alleviates acetaminophen-induced acute liver injury in mice
A universal nanostructured bioanalytical platform for NAD+-dependent enzymes based on the fluorescent output reading with a smartphone
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
Defined stereoisomers of 2 ″-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase
Selective Electrochemical Sensing of NADH and NAD+ Using Graphene/Tungstate Nanocomposite Modified Electrode
Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation
Tri-ortho-cresyl phosphate induces axonal degeneration in chicken DRG neurons by the NAD+ pathway
The science behind NMN–A stable, reliable NAD+ activator and anti-aging molecule
Metabolic aspects of neuronal degeneration: from a NAD+ point of view
Molecular Dynamics Analysis of a Rationally Designed Aldehyde Dehydrogenase Gives Insights into Improved Activity for the Non-Native Cofactor NAD+
NAD tagSeq for transcriptome-wide identification and characterization of NAD+-capped RNAs
Purification and structural characterization of the Na+-translocating ferredoxin: NAD+ reductase (Rnf) complex of Clostridium tetanomorphum
Caffeine and NAD+ Improve Motor Neural Integrity of Dissociated Wobbler Cells In Vitro
3D 31P MR spectroscopic imaging of the human brain at 3 T with a 31P receive array: An assessment of 1H decoupling, T1 relaxation times, 1H‐31P nuclear Overhauser …
Potential Therapeutic Benefit of NAD+ Supplementation for Glaucoma and Age-Related Macular Degeneration
NAD+ Precursors: A Questionable Redundancy
The ARH and Macrodomain Families of α-ADP-ribose-acceptor Hydrolases Catalyze α-NAD+ Hydrolysis
Probing NAD+/NADH-dependent biocatalytic transformations based on oxidase mimics of MnO2
Efficient Assay and Marker Significance of NAD+ in Human Blood
Innovations and Emerging Therapies to Combat Renal Cell Damage: NAD+ As a Drug Target
NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy
A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation
Up-regulation of miR-381 inhibits NAD+ salvage pathway and promotes apoptosis in breast cancer cells
NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence
NADomics: Measuring NAD+ and Related Metabolites Using Liquid Chromatography Mass Spectrometry
An integrated NAD+-dependent dehydrogenase-based biosensor for xylose fermentation sample analysis
NAD+ precursor increases aerobic performance in mice
NAD+ metabolism and cardiometabolic health: the human evidence
Laccase Did It again: A Scalable and Clean Regeneration System for NAD+ and Its Application in the Synthesis of 12-oxo-Hydroxysteroids
SIRT2, ERK and Nrf2 Mediate NAD+ Treatment-Induced Increase in the Antioxidant Capacity of PC12 Cells Under Basal Conditions
The level of secondary messengers and the redox state of NAD+/NADH are associated with sperm quality in infertility
Biguanide drugs enhance cytotoxic effects of cisplatin by depleting aspartate and NAD+ in sensitive cancer cells
Overexpression of NMNAT3 improves mitochondrial function and enhances antioxidative stress capacity of bone marrow mesenchymal stem cells via the NAD+-Sirt3 …
Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle
Sir2-domain associated short prokaryotic Argonautes provide defence against invading mobile genetic elements through NAD+ depletion
The chemical biology of NAD+ regulation in axon degeneration
Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1
NAD+-mediated rescue of prenatal forebrain angiogenesis restores postnatal behavior
The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate de novo NAD+ biosynthesis in budding yeast
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons
Inhibition of phosphate transport by NAD+/NADH in brush border membrane vesicles
… of diketopiperazine-containing 2-anilinobenzamides as potent sirtuin 2 (SIRT2)-Selective inhibitors targeting the “selectivity pocket”, substrate-binding site, and NAD+ …
Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging
Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD+ and SIRT3
Resveratrol attenuates excessive ethanol exposure-induced β-cell senescence in rats: A critical role for the NAD+/SIRT1-p38MAPK/p16 pathway
… model of the regression of alcoholic hepatitis: Monitoring the regression of hepatic steatosis, inflammation, oxidative stress, and NAD+ metabolism upon alcohol …
Long-chain fatty acids regulate SIRT3 expression by affecting intracellular NAD+ levels in large yellow croaker (Larimichthys crocea)
Role of NAD+—Modulated Mitochondrial Free Radical Generation in Mechanisms of Acute Brain Injury
Targeting NAD+ synthesis to potentiate CD38-based immunotherapy of multiple myeloma
Testing Abiotic Reduction of NAD+ Directly Mediated by Iron/Sulfur Minerals
Hypoxia-induced NAD+ interventions promote tumor survival and metastasis by regulating mitochondrial dynamics
Mitochondrial activity is the key to the protective effect of β-Lapachone, a NAD+ booster, in healthy cells against cisplatin cytotoxicity
Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction
Endurance exercise resistance to lipotoxic cardiomyopathy is associated with cardiac NAD+/dSIR2/PGC-1α pathway activation in old Drosophila
The Significance of NAD+ Biosynthesis Alterations in Acute Kidney Injury
Corneal denervation causes epithelial apoptosis through inhibiting NAD+ biosynthesis
Interplay between NAD+ and acetyl‑CoA metabolism in ischemia-induced mitochondrial pathophysiology
Structural insights into the NAD+-dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD+ ternary complex of the …
Regulation of carbon flux and NADH/NAD+ supply to enhance 2, 3-butanediol production in Enterobacter aerogenes
ACMSD: a novel target for modulating NAD+ homeostasis
Nicotinamide mononucleotide (NMN) deamidation by the gut microbiome and evidence for indirect upregulation of the NAD+ metabolome
The flavin transferase ApbE flavinylates the ferredoxin:NAD+-oxidoreductase Rnf required for N2 fixation in Azotobacter vinelandii
Streptococcus pyogenes can support or inhibit growth of Haemophilus influenzae by supplying or restricting extracellular NAD+
A cytosolic NAD+-dependent GPDH from maize (ZmGPDH1) is involved in conferring salt and osmotic stress tolerance
NAD+ Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis
The therapeutic promises of NAD+ boosters
NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice
Targeting NAD+: is it a common strategy to delay heart aging?
Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes
Compartmentalized regulation of NAD+ by Di (2-ethyl-hexyl) phthalate induces DNA damage in placental trophoblast
Current Uncertainties and Future Challenges Regarding NAD+ Boosting Strategies
Molecular characterization of a Novel NAD+-dependent farnesol dehydrogenase SoFLDH gene involved in sesquiterpenoid synthases from Salvia officinalis
Of mice and men: NAD+ boosting with niacin provides hope for mitochondrial myopathy patients
Electrochemical reduction of NAD+ on graphene oxide and chemically reduced graphene oxide nanosheets
Pathogen induced subversion of NAD+ metabolism mediating host cell death: a target for development of chemotherapeutics
Distinct roles of the NAD+-Sirt1 and FAD-LSD1 pathways in metabolic response and tissue development
Rationale for Nicotinamide Adenine Dinucleotide (NAD+) Metabolome Disruption as a Pathogenic Mechanism of Post-Acute COVID-19 Syndrome
Novel Pathway of Adenosine Generation in the Lungs from NAD+: Relevance to Allergic Airway Disease
CD38 and MGluR1 as possible signaling molecules involved in epileptogenesis: A potential role for NAD+ homeostasis
NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes
Signaling and Regulation Through the NAD+ and NADP+ Networks
The Identification of a Novel Calcium-Dependent Link Between NAD+ and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress
NAD+ Degrading Enzymes, Evidence for Roles During Infection
NAD+ biosynthesis in bacteria is controlled by global carbon/nitrogen levels via PII signaling
One‐pot highly efficient synthesis of n‐enrich graphene quantum dots as a photocatalytic platform for NAD+/NADP+ reduction
Risks and rewards of targeting NAD+ homeostasis in the brain
Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
Self-association configures the NAD+-binding site of plant NLR TIR domains
Suppression of metabolite shuttles for export of chloroplast and mitochondrial ATP and NADPH increases the cytosolic NADH: NAD+ ratio in tobacco leaves in the …
Supplemental Nicotinic Acid Elevates NAD+ Precursors in the Follicular Fluid of Mares
Metabolic analyses reveal dysregulated NAD+ metabolism and altered mitochondrial state in ulcerative colitis
Supplementing media with NAD+ precursors enhances the in vitro maturation of porcine oocytes
Modulation of Cellular NAD+ Attenuates Cancer-Associated Hypercoagulability and Thrombosis via the Inhibition of Tissue Factor and Formation of …
Modulation of aryl hydrocarbon receptor (AHR) and the NAD+-consuming enzyme CD38: Searches of therapeutic options for nonalcoholic fatty liver disease (NAFLD)
Alpha-synucleinopathy reduces NMNAT3 protein levels and neurite formation that can be rescued by targeting the NAD+ pathway
Roles of NAD+ and Its Metabolites Regulated Calcium Channels in Cancer
TFB2M activates aerobic glycolysis in hepatocellular carcinoma cells through the NAD+/SIRT3/HIF‐1α signaling
vp1524, a Vibrio parahaemolyticus NAD +-dependent deacetylase, regulates host response during infection by induction of host histone deacetylation
NAD+ boosting brings tears to aging eyes
Reverse metabolic engineering in lager yeast: impact of the NADH/NAD+ ratio on acetaldehyde production during the brewing process
Growth of carbon nanotubes on graphene as 3D biocathode for NAD+/NADH balance model and high-rate production in microbial electrochemical synthesis from CO …
Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD+ homeostasis during aging
Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
… of metal organic frameworks derived hierarchical porous carbon on carbon nanotubes as efficient bioanode catalysts of NAD+-dependent alcohol dehydrogenase
Sex-related differences in human plasma NAD+/NADH levels depend on age
Electrocatalytic NAD+ reduction via hydrogen atom-coupled electron transfer
Potent Activation of NAD+-Dependent Deacetylase Sirt7 by Nucleosome Binding
Importance of adipose tissue NAD+ biology in regulating metabolic flexibility
Structure of the Streptococcus pyogenes NAD+ Glycohydrolase Translocation Domain and Its Essential Role in Toxin Binding to Oropharyngeal Keratinocytes
The histone deacetylases Rpd3 and Hst1 antagonistically regulate de novo NAD+ metabolism in the budding yeast Saccharomyces cerevisiae
NAD+ deficit, protein acetylation and muscle aging
Identification of the Arabidopsis Calmodulin-Dependent NAD+ Kinase That Sustains the Elicitor-Induced Oxidative Burst
NAD+ Inhibits the Metabolic Reprogramming of RPE Cells in Early Age-related Macular Degeneration by Upregulating Mitophagy
Impact of Nuclear De Novo NAD+ Synthesis via Histone Dynamics on DNA Repair during Cellular Senescence To Prevent Tumorigenesis
Multi-Systemic Alterations by Chronic Exposure to a Low Dose of Bisphenol A in Drinking Water: Effects on Inflammation and NAD+-Dependent Deacetylase …
Roles of NAD+ in Acute and Chronic Kidney Diseases
Enhance Trial: Effects of NAD3® on Hallmarks of Aging and Clinical Endpoints of Health in Middle Aged Adults: A Subset Analysis Focused on Blood Cell NAD+ …
NAD+ Metabolism and Interventions in Premature Renal Aging and Chronic Kidney Disease
Direct electrical contact of NAD+/NADH-dependent dehydrogenase on electrode surface enabled by non-native solid-binding peptide as a molecular binder
The new insight into extracellular NAD+ degradation‐the contribution of CD38 and CD73 in calcific aortic valve disease
A single oral supplementation of nicotinamide within the daily tolerable upper level increases blood NAD+ levels in healthy subjects
A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy
Sexually dimorphic effects of SARM1 deletion on cardiac NAD+ metabolism and function
Mitochondrial and peroxisomal NAD+ uptake are important for improved photosynthesis and seed yield under elevated CO2 concentrations
Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells
Inhibition of mitochondrial complex I leading to NAD+/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: Evidence from an …
Enhancing the ascorbate–glutathione cycle reduced fermentation by increasing NAD+ levels during broccoli head storage under controlled atmosphere
The Gro3p factor: Restoring NAD+/NADH homeostasis to ameliorate mitochondrial disease
The extracellular lactate-to-pyruvate ratio modulates the sensitivity to oxidative stress-induced apoptosis via the cytosolic NADH/NAD+ redox state
Intracellular NAD+ Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation
Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD+ synthetases
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP
NAD+ Levels Are Augmented in Aortic Tissue of ApoE−/− Mice by Dietary Omega-3 Fatty Acids
AMPK phosphorylates NAMPT to regulate NAD+ homeostasis under ionizing radiation
Characterization of NAD+/NADP+-Specific Isocitrate Dehydrogenases From Oleaginous Fungus Mortierella alpina Involved in Lipid Accumulation
Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD+-Dependent Enzymes and Plant-Derived Natural Products
Substituent Effects on Temperature Dependence of Kinetic Isotope Effects in Hydride-Transfer Reactions of NADH/NAD+ Analogues in Solution: Reaction Center …
Crystal structures of pertussis toxin with NAD+ and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity
Direct Correlation between Donor–Acceptor Distance and Temperature Dependence of Kinetic Isotope Effects in Hydride-Tunneling Reactions of NADH/NAD+ …
Dynamics study on the non-adiabatic Na (3p)+ HD→ NaH/NAD+ D/H reaction: insertion–abstraction mechanism
Biomimetic Molecular Clamp Nanopores for Simultaneous Quantifications of NAD+ and NADH
NAD+-dependent Glsirt1 has a key role on secondary metabolism in Ganoderma lucidum
Lactate metabolism in strictly anaerobic microorganisms with a soluble NAD+‐dependent l‐lactate dehydrogenase
A hybrid system integrating xylose dehydrogenase and NAD+ coupled with PtNPs@ MWCNTs composite for the real-time biosensing of xylose
KLF15 Regulates Oxidative Stress Response in Cardiomyocytes through NAD+
NAD+ repletion inhibits the endothelial-to-mesenchymal transition induced by TGF-β in endothelial cells through improving mitochondrial unfolded protein response
M. tuberculosis class II apurinic/ apyrimidinic‐endonuclease/3′‐5′ exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile …
… study of single oral supplementation within the daily tolerable upper level of nicotinamide affects blood nicotinamide and NAD+ levels in healthy subjects
Constraints-based analysis identifies NAD+ recycling through metabolic reprogramming in antibiotic resistant Chromobacterium violaceum
NAD+ attenuates cardiac injury after myocardial infarction in diabetic mice through regulating alternative splicing of VEGF in macrophages
Circadian cardiac NAD+ metabolism, from transcriptional regulation to healthy aging
Deletion of CD38 and supplementation of NAD+ attenuate axon degeneration in a mouse facial nerve axotomy model
NAD+ Kinase Enzymes Are Reversible, and NAD+ Product Inhibition Is Responsible for the Observed Irreversibility of the Human Enzyme
NAD+ Precursors Repair Mitochondrial Function in Diabetes and Prevent Experimental Diabetic Neuropathy
Declining muscle NAD+ in a hyperandrogenism PCOS mouse model: Possible role in metabolic dysregulation
After virus exposure, early bystander naïve CD8 T cell activation relies on NAD+ salvage metabolism
Functional definition of NrtR, a remnant regulator of NAD+ homeostasis in the zoonotic pathogen Streptococcus suis
Apprehending the NAD+–ADPr-Dependent Systems in the Virus World
Eosinophil peroxidase oxidizes isoniazid to form the active metabolite against M. tuberculosis, isoniazid-NAD+
Progresses in both basic research and clinical trials of NAD+ in Parkinson’s disease
Hypothalamic NAD+-Sirtuin Axis: Function and Regulation
Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD+ salvage pathway mutant
NAD+ depletion enhances reovirus-induced oncolysis in multiple myeloma
Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios
NAD+ and its possible role in gut microbiota: insights on the mechanisms by which gut microbes influence host metabolism
How Does Fusarium oxysporum Sense and Respond to Nicotinaldehyde, an Inhibitor of the NAD+ Salvage Biosynthesis Pathway?
Imbalanced Transition States from α-H/D and Remote β-Type N-CH/D Secondary Kinetic Isotope Effects on the NADH/NAD+ Analogues in Their Hydride Tunneling …
Viewing teratogens through the lens of nicotinamide adenine dinucleotide (NAD+)
Mitochondrial Deoxyguanosine Kinase Regulates NAD+ Biogenesis Independent of Mitochondria Complex I Activity
Maestro of the SereNADe: SLC25A51 orchestrates mitochondrial NAD+
A decrease in NAMPT activity impairs basal PARP-1 activity in cytidine deaminase deficient-cells, independently of NAD+
The Clock‐NAD+‐Sirtuin connection in nonalcoholic fatty liver disease
CD38-expressing macrophages drive age-related NAD+ decline
Assays for Determination of Cellular and Mitochondrial NAD+ and NADH Content
Discriminating changes in intracellular NADH/NAD+ levels due to anoxicity and H2 supply in R. eutropha cells using the Frex fluorescence sensor
Insights into the modulation of the interferon response and NAD+ in the context of COVID-19
NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway
NAD+ depletion radiosensitizes 2-DG-treated glioma cells by abolishing metabolic adaptation
NAMPT-mediated NAD+ biosynthesis suppresses activation of hepatic stellate cells and protects against CCl4-induced liver fibrosis in mice
Flexible NAD+ Binding in Deoxyhypusine Synthase Reflects the Dynamic Hypusine Modification of Translation Factor IF5A
Enhanced production of seed oil with improved fatty acid composition by overexpressing NAD+‐dependent glycerol‐3‐phosphate dehydrogenase in soybean
A novel strategy for the application of levulinic acid with simultaneous NAD+ regeneration and membrane separation of products
Association between NAD+ levels and anaemia among women in community‐based study
Emissive Synthetic Cofactors: A Highly Responsive NAD+ Analogue Reveals Biomolecular Recognition Features
Critical role of astrocyte NAD+ glycohydrolase in myelin injury and regeneration
NAD+/sirtuin metabolism is enhanced in response to cold‐induced changes in lipid metabolism in mouse liver
The effect of 4-hexylresorinol administration on NAD+ level and SIRT activity in Saos-2 cells
NAD+ metabolism controls growth inhibition by HIF1 in normoxia and determines differential sensitivity of normal and cancer cells
Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
NAD+ in sulfur mustard toxicity
Differences in Extracellular NAD+ and NMN Metabolism on the Surface of Vascular Endothelial Cells
The combined treatment of NAD+ and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice
Discovery of an NAD+ analogue with enhanced specificity for PARP1
Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire
Targeting on the NAD+‐mitophagy axis to treat cardiovascular disease
NAD+ oscillation and hypothalamic neuronal functions
NAD+-Increasing Strategies to Improve Cardiometabolic Health?
… promotes Chlamydia trachomatis L2/434/Bu growth in immortal human epithelial cells via activation of the PI3K-AKT pathway and maintenance of a balanced NAD+ …
Evolution of Distinct Responses to Low NAD+ Stress by Rewiring the Sir2 Deacetylase Network in Yeasts
Could NAD+ Precursor Supplements Induce a Legacy of Protection against Diabetic Nephropathy?
… Ruthenium (II) Polypyridylamine Complex Catalyze Hydride Transfer? Mechanistic Insight from Solution Kinetics on the Reduction of Coenzyme NAD+ by Formate
Electronic effects on the mechanism of the NAD+ coenzyme reduction catalysed by a non-organometallic ruthenium (ii) polypyridyl amine complex in the …
NAD+ and human muscle health
The NAD+ Responsive Transcription Factor ERM-BP Functions Downstream of Cellular Aggregation and Is an Early Regulator of Development and Heat Shock …
The tetrameric assembly of 2‐aminomuconic 6‐semialdehyde dehydrogenase is a functional requirement of cofactor NAD+ binding
Nicotinic acid supplementation at a supraphysiological dose increases the bioavailability of NAD+ precursors in mares
The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD+ Level Is Lower than the Sirtuin-Saturating Concentrations
Fiber optic surface plasmon resonance based lactate sensor using co-immobilization of lactate dehydrogenase and NAD+
Hydrogen production based on the heterologous expression of NAD+-reducing [NiFe]-hydrogenase from Cupriavidus necator in different genetic backgrounds of …
Potentiating the anti-tumor response of tumor infiltrated T cells by NAD+ supplementation
Nicotinamide improves NAD+ levels to protect against acetaminophen-induced acute liver injury in mice
Multi‐walled Carbon Nanotubes Non‐covalently Functionalized with Polyarginine: A New Alternative for the Construction of Reagentless NAD+/Dehydrogenase …
The potential of the novel NAD+ supplementing agent, SNH6, as a therapeutic strategy for the treatment of Friedreich’s ataxia
Structure: Function Studies of the Cytosolic, Mo- and NAD+-Dependent Formate Dehydrogenase from Cupriavidus necator
β-Lapachone protects against doxorubicin-induced nephrotoxicity via NAD+/AMPK/NF-kB in mice
Stem cell derived astrocytes with POLG mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neurons
Effects of NAD+ in Caenorhabditis elegans Models of Neuronal Damage
P-200 An addition of nicotinamide adenine dinucleotide (NAD+) precursor to oocyte maturation medium improves the developmental competence of bovine oocytes …
… organorhodium and-iridium complexes: synthesis, antiplasmodial activity and preliminary evaluation as transfer hydrogenation catalysts for the reduction of NAD+
Rhodium-Complex-Functionalized and Polydopamine-Coated CdSe@CdS Nanorods for Photocatalytic NAD+ Reduction
NAD+ attenuates bilirubin-induced augmentation of voltage-gated calcium currents in neurons of the ventral cochlear nucleus
Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice
UDP-glucose dehydrogenase: the first-step oxidation is an NAD+-dependent bimolecular nucleophilic substitution reaction (SN2)
Author Correction: Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Enhancing NAD+ Metabolome in Cardiovascular Diseases: Promises and Considerations
NAD+ prevents septic shock by non-canonical inflammasome blockade and IL-10
Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC
… induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+ …
The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Biochemical Characterization and Crystal Structure of a Novel NAD+-Dependent Isocitrate Dehydrogenase from Phaeodactylum tricornutum
Cross-talk in NAD+ metabolism–insights from Saccharomyces cerevisiae
In silico insights into potential gut microbial modulation of NAD+ metabolism and longevity
Cross-talk in NAD+ metabolism: insights from Saccharomyces cerevisiae
Biochemical characterization and redesign of the coenzyme specificity of a novel monofunctional NAD+-dependent homoserine dehydrogenase from the human …
Prediction of Cervical Cancer Outcome by Identifying and Validating a NAD+ Metabolism-Derived Gene Signature
NAD+-dependent Mechanism of Pathological Axon Degeneration
Bioinspired redox-driven NAD+ pump membranes with composition of annulated and cylindrical channel
A Theacrine-Based Supplement Increases Cellular NAD+ Levels and Affects Biomarkers Related to Sirtuin Activity in C2C12 Muscle Cells In Vitro
GlSir2. 1 of Giardia lamblia is a NAD+-dependent cytoplasmic deacetylase
Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction
NMR solution structures of Runella slithyformis RNA 2′-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity
Xanthine oxidoreductase knockout mice with high HPRT activity were not rescued by NAD+ replenishment
Ozone Exposure Induces Metabolic Disorders and NAD+ Depletion Through PARP1 Activation in Spinal Cord Neurons
A case of Parkinson’s disease symptom reduction with intravenous NAD+
NAD+ Homeostasis in Diabetic Kidney Disease
Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with NAD+-Dependent Enzymes
Streptococcus pyogenes NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O
Structural Basis of Redox-Sensing Transcriptional Repressor Rex with Cofactor NAD+ and Operator DNA
Maintenance of NAD+ homeostasis in skeletal muscle during aging and exercise
Efficient L-xylulose production using whole-cell biocatalyst with NAD+ regeneration system through co-expression of xylitol dehydrogenase and NADH oxidase in …
Identification of l‐Tryptophan by down‐field 1H MRS: A precursor for brain NAD+ and serotonin syntheses
Effect of Met/Leu substitutions on the stability of NAD+-dependent formate dehydrogenases from Gossypium hirsutum
Role of potassium levels in pkBADH heterogeneity of NAD+ binding site
Senescence of timing reverted: NAD+ rejuvenates the circadian clock
Resveratrol and Quercetin Potentiate the Cell Protection and Rescue Effects of NAD+ Precursors in HEK293 Cells Challenged by DNA Damaging Agent, N-Methyl-N′ …
NAD+ metabolism controls inflammation during senescence
Safety Evaluation for Restorin® NMN, a NAD+ Precursor
Improved Productivity of NAD+ Reduction under Forced Convection in Aerated Solutions
The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD+ levels
Methotrexate use and NAD+/NADH metabolism in psoriatic keratinocytes
N-terminal protein acetylation by NatB modulates the levels of Nmnats, the NAD+ biosynthetic enzymes in Saccharomyces cerevisiae
Selenium Supplementation Protects Against Arsenic-Trioxide-Induced Cardiotoxicity Via Reducing Oxidative Stress and Inflammation Through Increasing NAD+ Pool
Engineering of Escherichia coli Glyceraldehyde-3-Phosphate Dehydrogenase with Dual NAD+/NADP+ Cofactor Specificity for Improving Amino Acid Production
Intensifying niacin-based biosynthesis of NAD+ to enhance 3-hydroxypropionic acid production in Klebsiella pneumoniae
NAD+ capping of RNA in Archaea and Mycobacteria
NAD+, Sirtuins and PARPs: enhancing oocyte developmental competence
… dehydrogenases are encoded in Leishmania parasites. Molecular and functional characterization of Leishmania mexicana isoenzymes with specificity towards NAD+ …
A Novel Photo-Driven Hydrogenation Reaction of an NAD+-Type Complex Toward Artificial Photosynthesis
NAD+ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition
Restoration of NAD+ homeostasis protects C2C12 myoblasts and mouse levator ani muscle from mechanical stress-induced damage
NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV
A Regulatory Cysteine Residue Mediates Reversible Inactivation of NAD+-Dependent Aldehyde Dehydrogenases to Promote Oxidative Stress Response
Exogenous NAD+ Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway
NAD+ the disregarded molecule in cardiac metabolism
Role of rare-earth elements in enhancing bioelectrocatalysis for biosensing with NAD+-dependent glutamate dehydrogenase
Nicotinamide Mononucleotide Adenylyltransferase 1 Regulates Cerebral Ischemia–Induced Blood–Brain Barrier Disruption Through NAD+/SIRT1 Signaling Pathway
Developing a single strain for in vitro salvage synthesis of NAD+ at high temperatures and its potential for bioconversion
NAD+-dependent RNA terminal 2′ and 3′ phosphomonoesterase activity of a subset of tpt1 enzymes
An NAD+ dependent/sensitive transcription system: Toward a novel anti-cancer therapy
Time-of-day defines the efficacy of NAD+ to treat diet-induced metabolic disease by adjusting oscillations of the hepatic circadian clock
Compartmentalization Accelerates Photosensitized NADH to NAD+ Conversion
Crystal structures of NAD+-linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP+-linked …
Cell Type–Specific Roles of CD38 in the Interactions of Isoniazid with NAD+ in the Liver
FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts
Cellular NAD+, fibroblast senescence and pulmonary fibrosis
The iNADequacy of renal cell metabolism: modulating NAD+ biosynthetic pathways to forestall kidney diseases
Na+-Translocating Ferredoxin:NAD+ Oxidoreductase Is a Component of Photosynthetic Electron Transport Chain in Green Sulfur Bacteria
NAD+ flux is maintained in aged mice
Genes of NAD+-Dependent Formate Dehydrogenases in Taxonomy of Aerobic Methylotrophic Bacteria of the Genus Ancylobacter
NAD+ biosynthetic impairment and urinary metabolomic alterations observed in hospitalized adults with COVID-19-related acute kidney injury.
CD38-NAD+-Sirt1 axis in T cell immunotherapy
Flow Cytometry Analysis of Free Intracellular NAD+ Using a Targeted Biosensor
Treatment of SARS-CoV-2 induced pneumonia with NAD+ in a mouse model
Nicotinamide riboside augments the human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a …
Xylose Fermentation Was Improved by Kluyveromyces marxianus KHM89 through Up-regulation of Nicotinamide Adenine Dinucleotide (NAD+) Salvage Pathway
Brain aging-dependent glioma traits reversible by NAD+/BDNF-mediated neuronal reactivation
Performance comparison with different methods for ethanol/O2 biofuel cell based on NAD+ cofactor immobilized and activated by two types of carbon nanoparticles
Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD+/Sirt3 Pathway in …
Peroxisome proliferator-activated receptor γ coactivator 1α maintains NAD+ bioavailability protecting against steatohepatitis
Substituted benzoic acid amides as the modifiers of the ethanol bioelectrooxidation using NAD+-dependent alcohol dehydrogenase
The Role of NAD+ in Regenerative Medicine
Homologous role of CovRS two‐component regulatory system in NAD+‐glycohydrolase activity in Streptococcus dysgalactiae subsp. equisimilis as in Streptococcus …
ODP443 Targeting NAD+ availability modulates 11β-Hydroxysteroid dehydrogenase 1 activity in mouse and human cell lines and primary cells
The role of Tyr102 residue in the functioning of bacterial NAD+-dependent formate dehydrogenase of Pseudomonas sp. 101
P–175 Possible role of NAD+ metabolism in oocyte aging: insights from gene expression profiles in reproductive aged oocytes
An NAD+/NMN balancing act by SARM1 and NMNAT2 controls axonal degeneration
Quantification of NAD+ in human brain with 1H MR spectroscopy at 3 T: Comparison of three localization techniques with different handling of water magnetization
NAD+: a metabolic knob fine-tuning inflammation during senescence
eP032: Measurement of Nicotinamide Adenine Dinucleotide (NAD+) from dried blood spot cards
A Clickable NAD+ Analog-Based Assay of Poly(ADP-Ribosyl)ated Proteins
Bioactive Oligopeptides from Ginseng (Panax ginseng Meyer) Suppress Oxidative Stress-Induced Senescence in Fibroblasts via NAD+/SIRT1/PGC-1α …
Fusobacterium nucleatum promotes the development of acute liver failure by inhibiting the NAD+ salvage metabolic pathway
Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells
Jian-Pi-Yi-Shen Formula Alleviates Chronic Kidney Disease in Two Rat Models by Modulating QPRT/NAD+/SIRT3/Mitochondrial Dynamics Pathway
An NAD+-type earth-abundant metal complex enabling photo-driven alcohol oxidation
Tolerance to NADH/NAD+ imbalance anticipates aging and anti-aging interventions
NAD+ Metabolism in Aging
NAD+ cleavage: TIR domain-containing resistance proteins in action
Overexpression of NMNAT3 improves mitochondrial function and enhances anti-oxidative stress of bone marrow mesenchymal stem cells via the NAD+-Sirt3 pathway
Characterization of the nicotinamide adenine dinucleotides (NAD+ and NADP+) binding sites of the monomeric isocitrate dehydrogenases from Campylobacter …
NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2
BADH-NAD+-K+ Complex Interaction Studies Reveal a New Possible Mechanism between Potassium and Glutamic 254 at the Coenzyme Binding Site
Nicotinamide Adenine Dinucleotide (NAD+) in Aging
NAD+ biosynthesis as a collateral lethality target for precision oncology
Reconfigurable Implication and Inhibition Boolean logic gates based on NAD+‐dependent enzymes: Application to signal‐controlled biofuel cells and molecule …
β-Nicotinamide Monucleotide Supplement with Astaxanthin and Blood Orange Enhanced NAD+ Bioavailability and Mitigated Age-Associated Physiological Decline in …
Nicotinamide Adenine Dinucleotide (NAD+) and Enkephalinase Inhibition (IV1114589NAD) Infusions Significantly Attenuate Psychiatric Burden Sequalae in …
A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells
Glutathione and oxidized nicotinamide adenine dinucleotide (NAD+) redox status in plasma and placental tissue of Saudi patients with intrauterine growth …
Nicotinamide adenine dinucleotide (NAD+) biosynthesis in the regulation of metabolism, aging, and neurodegeneration
NAD+ supplementation reverses the oxidative stress induced PARP1 signalling in D. discoideum
Ligand Binding in Allosteric Flavoproteins: Part 1. Quantitative Analysis of the Interaction with NAD+ of the Apoptosis Inducing Factor (AIF) Harboring FAD in the …
Tracking the Courier: In Planta Imaging of NADH/NAD+ Ratios with a Genetically Encoded Biosensor
Association of NAD+ ADP-ribosyltransferase 1 gene polymorphism with the development of neonatal diabetes mellitus
NAD+ is critical for maintaining acetyl-CoA and H3K27ac in embryonic stem cells by Sirt1-dependent deacetylation of AceCS1
Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease
Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD+-dependent DNA ligase A
Addiction: the Dark Night of the Soul/NAD+: the Light of Hope
Relationship between sperm NAD+ concentration and reproductive aging in normozoospermia men: A Cohort study
C/EBPβ-LIP dually activates glycolysis and the malate aspartate shuttle to maintain NADH/NAD+ homeostasis
Effects of exercise training on aging-related NAD+/sirt1 pathway In middle-aged and aged mice
Fatty Acid Desaturation Gets a NAD+ Reputation
The Role of NAD+ and Nicotinamide (Vitamin B3) in Glaucoma: A Literature Review
Metabolic Stress Resistance in AKI: Evidence for a PGC1α-NAD+ Pathway
NAD+ keeps the clock young
Possible Therapeutic Potential of Flavonoids and Phenolic Acids from Honey in Age-Related Neurodegenerative Diseases Via Targeting NAD+ Degradation
Purification of Adult Hymenolepis diminuta (Cestoda) Mitochondrial NADPH→NAD+ Transhydrogenase
Augmentation of NAD+ by Dunnione Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice
Ectopic Expression of Rv0023 Mediates Isoniazid/Ethionamide Tolerance via Altering NADH/NAD+ Levels in Mycobacterium smegmatis
Correction to “A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes”
Need for NAD+: Focus on Striated Muscle Laminopathies
Salvaging the endothelium in acute respiratory distress syndrome: a druggable intersection between TLR4 and NAD+ signalling
Circulating NAD+ metabolism-derived genes unveils prognostic and peripheral immune infiltration in amyotrophic lateral sclerosis
Identification of the Calmodulin-dependent NAD+ kinase sustaining the elicitor-induced oxidative burst in plants
The mechanism of nicotinamide phosphoribosyltransferase whereby positive allosteric modulation elevates cellular NAD+
Identification of NAD+ metabolism-derived gene signatures in ovarian cancer prognosis and immunotherapy
Insights into the NAD+ biosynthesis pathways involved during meiotic maturation and spindle formation in porcine oocytes
Expression, purification, and biochemical characterization of an NAD+-dependent homoserine dehydrogenase from the symbiotic Polynucleobacter necessarius …
Role of NAD+ in regulating cellular and metabolic signaling pathways
Membraneless ethanol, O2 enzymatic biofuel cell based on laccase and ADH/NAD+ bioelectrodes
Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD+-dependent DNA ligase A (MtbLigA) …
Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD+ in medium-chain acyl-CoA dehydrogenase knockout mice
Targeting NAD+ synthesis to boost mitochondrial function and protect the kidney
Phagocytosis and self-destruction execute dendrite degeneration of Drosophila sensory neurons at distinct levels of NAD+ reduction
ODP205 Hepatic steatosis induced by Nicotine plus Coca Cola is prevented by Nicotinamide riboside (NR) that increases mitochondrial NAD+
Association of human whole blood NAD+ contents with aging
Coordination between metabolic transitions and gene expression by NAD+ availability during adipogenic differentiation in human cells
Salvage NAD+ biosynthetic pathway enzymes moonlight as molecular chaperones to protect against proteotoxicity
… phylogenetic and biochemical analysis of NADH diphosphatases reveals that the enzyme from Tuber melanosporum is highly active towards NAD+
Prognostic value of nicotinamide adenine dinucleotide (NAD+) metabolic genes in patients with stomach adenocarcinoma based on bioinformatics analysis
Nuclear NAD+ homeostasis is essential for naive and chemoresistant BRCA1/2-deficient tumor survival
Quantitative Analysis of Redox Pool (NAD+, NADH Content) in Plant Samples Under Aluminum Stress
NAD-seq for profiling the NAD+ capped transcriptome of Arabidopsis thaliana
Cardiac Nmnat/NAD+/SIR2 pathways activation mediates endurance exercise resistance to heart defects induced by a high-fat diet in aging Drosophila
The novel conserved NAD+-binding micropeptide SGHRT regulates mitochondrial function and metabolism in human cardiomyocytes
Probing Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Reaction Cycle Intermediates
Construction of a third NAD+ de novo biosynthesis pathway
Chemoenzymatic Preparation of 4′‐Thioribose NAD+
Early loss of endogenous NAD+ following rotenone treatment leads to Sarm1 activation that is ameliorated by PARP inhibition
NAD+ attenuates experimental autoimmune encephalomyelitis through induction of CD11b+ gr-1+ myeloid-derived suppressor cells
Qualitative and Quantitative NAD+ Metabolomics Lead to Discovery of Multiple Functional Nicotinate N-Glycosyltransferase in Arabidopsis
Synthesis of [4S‐2H]NADH, [4R‐2H]NADH, [4‐2H2]NADH and [4‐2H]NAD+ cofactors through heterogeneous biocatalysis in heavy water
Molecular imaging of NAD+‐dependent deacetylase SIRT1 in the brain
Evidence for NAD+-dependent histone dynamics and tunneling associated conformational transitions in circadian deacetylase SIRT1
A combination of natural polyphenols, a NAD+ booster, and a Toll-like receptor 2/6 agonist exerts high radioprotection in normal tissues without interfering with the …
POS0394 NAD+ BOOSTERS REESTABLISH THE ALTERED NAD+ METABOLISM OF LEUKOCYTES FROM RHEUMATOID ARTHRITIS PATIENTS …
Mono (ADP-ribosyl) ation Enzymes and NAD+ Metabolism: A Focus on Diseases and Therapeutic Perspectives. Cells 2021, 10, 128
Dynamics of Mitochondrial NAD+ Import Reveal Preference for Oxidized Ligand and Substrate Led Transport
NMNAT2 and NAD+ are Downregulated in Glaucomatous RGCs and Overexpression of NMNAT2 Rescues Glaucomatous Neurodegeneration
Research Progress in NAD+ Cap Modification at the 5’End of RNA
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos
Mitochondrial Kinase Regulates Deoxyguanosine NAD+ Biogenesis Independent of Mitochondria Complex I Activity
Role of PARP1 and NAD+ Bioavailability in Base Excision and Single-Strand Break Repair
Period 3 regulates mitochondrial function via the NAD+-SIRT3 axis in mice
Restoration of NAD+ levels as a therapy for HFpEF
Nicotinamide Adenine Dinucleotide (NAD+) improves lung function in rat lung ex-vivo lung perfusion model
Novel antitumor semi-synthetic heliomycin derivatives direct targeting tNOX-NAD+-SIRT1 axis to activate apoptosis/autophagy, as determined by the cellular thermal …
Impact of Low pH on Microbial Growth Rate, ATP Production, and NADH to NAD+ ratio
Exogenous NAD+ Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 Signaling. Antioxidants 2021, 10, 254
Welcome to the Family: Identification of the NAD+ Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25
The tetrameric assembly of 2-aminomuconic acid dehydrogenase is a functional requirement of cofactor NAD+ binding
The Effect of Nicotinamide Riboside, an NAD+ Precursor, on Glycolysis and NAD+ Salvage Pathway in Alcohol-Stimulated Macrophages
Effect of the Components of a Buffer Solution on the Catalytic Activity of the NAD+-Dependent Formate Dehydrogenase from the Bacterium Staphylococcus aureus
Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications
Mycobacterium smegmatis msmeg_3314 is involved in pyrazinamide and fluoroquinolones susceptibility via NAD+/NADH dysregulation
Nicotinamide mononucleotide enhances the efficacy and persistence of CD19 CAR-T cells via NAD+–Sirt1 axis
Attempts towards Total Synthesis of Photocaged Nicotinamide Adenine Dinucleotide (NAD+) and Its Analogues
Extracellular Hydrolysis of NAD+ and its Secondary Metabolites by a new Aspergillus sp
NAD+/NADH precursor treatment protects against retinal degeneration
Nicotinamide NAD+ Content Increases to Enhance Intracellular Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells
Recombinant Production of E. coli NAD+-dependent DNA ligase as a Target for Antibacterial Drug Discovery
Erratum: Hopp, AK, et al. Regulation of Glucose Metabolism by NAD+ and ADP-Ribosylation. Cells 2019, 8, 890
Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications.
Antioxidant and Anti-Infl ammatory Eff ects of Nicotinamide Adenine Dinucleotide (NAD+) Against Acute Hepatorenal Oxidative Injury in An Experimental Sepsis …
Effects of NAD+ Synthesis Levels on Sirtuin 1 Deacetylase Activity in Mammalian Cells
NAM-NAD+-ADO metabolic reprogramming is a key factor for DNMT3A mutation to promote leukemia development through regulating cell cycle and immune …
Protection against chemotherapy induced infertility through elevation of NAD+
NAD+ Metabolism as an Emerging Therapeutic Target for Cardiovascular Diseases Associated With Sudden Cardiac Death
Role of NAD+ level by NQO1 enzymatic action in regulation of hair regrowth that prevents chemotherapy-induced alopecia
The Role of eNAMPT-Mediated Systemic NAD+ Biosynthesis in Aging and Lifespan
Effects of NAD+ booster NMN on ovarian function and late-life bone health
Therapeutic Potential of NAD+ Precursors and Aging-related Diseases
Multi-omics analysis reveals the NAD+ salvage pathway as defense mechanism against Streptococcus pneumoniae infection
Poly ADP-ribose polymerase inhibition enhances T cell cytotoxicity and anti-tumor function by altering NAD+ levels
Sevoflurane preconditioning alleviates myocardial ischemia reperfusion injury through mitochondrial NAD+-SIRT3 pathway in rats.
Tannic acid-induced modulation of poly (ADP-ribose) glycohydrolase and NAD+ content in rat liver and thymocyte nuclei
The interplay between NAD+, SIRT1 and circadian rhythms in cellular ageing and fibrosis
Nicotinamide riboside, an NAD+ precursor, reduces hepatic stellate cell activation and attenuates liver fibrosis in a diet-induced mouse model of liver fibrosis …
Intracellular NAD+ depletion promotes NLRP3 inflammasome activation
Intravenous Uptake of NMN is Safely Metabolize and Increases NAD+ Levels in Healthy Subjects
Genomic Analysis Of NAD+ Synthesis Pathways Involved In Aging and Cancer
Correction to: Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice
Polydopamine coated CdSe@ CdS dot-in-rod heterostructures with Rhodium-based catalysts for stable photocatalytic NAD+ reduction
NAD+ to assess health in aging humans
Solvent Polarity Effects on the Temperature Dependence of Primary Kinetic Isotope Effects of NADH/NAD+ Model Reactions in Solution
Effect of Time of Aerobic Exercise in the Light-dark Cycle on Glycemic Control, SIRT1 Protein Expression, and NAD+/NADH Ratio in Skeletal Muscle of Type 2 …
NAD+ precursor concentrations are elevated in the follicular fluid of mares following oral supplementation of nicotinic acid
KLF15 Regulates Oxidative Stress Response in Cardiomyocytes through NAD+. Metabolites 2021, 11, 620
Subcellular characterization of NAD+ biosynthesis in metastatic melanoma by using organelle-specific biosensors
TAMI-20. POLY (ADP-RIBOSE) GLYCOHYDROLASE INHIBITION SEQUESTERS NAD+ TO POTENTIATE THE METABOLIC LETHALITY OF ALKYLATING …
OR03-06 NAD+ Availability Modulates 11β-HSD1-Mediated Glucocorticoid Regeneration in Mouse Skeletal Muscle
Investigating the Intersection of Metabolism and NAD+-Consuming Enzymes in Intestinal Homeostasis and Disease
Ectopic Expression of Rv0023 Mediates Tolerance Isoniazid/Ethionamide via Altering NADH/NAD+ Levels in Mycobacterium smegmatis
Changes in NADH, H+: NAD+ of Pseudomonas taetrolens may be used to assess the effectiveness of PCB dredging in the Hudson River
The role of NAD+ compartmentation and dynamics in Arabidopsis thaliana
On the electrochemical NADH regeneration: Influence of electrode potential, pH and NAD+ concentration
Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing
Protocols for analyzing metabolic derangements caused by increased NADH/NAD+ ratio in cell lines and in mice
miR-34a Suppression Ameliorates Bone Marrow Mesenchymal Stem Cell Senescence by Targeting Nampt and Regulating NAD +-Sirt1 Pathway
Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD+, Causes Reductive Stress, and Suppresses Glycolysis and Cell Growth
Roles of the Histone Deacetylases Rpd3 and Hst1 in the Regulation of NAD+ Metabolism
Mutational Analysis of SLC25A51 Residues Important for NAD+ Binding and Transport
Case Report 1: NAD+ Oscillation Therapy (NOT) to treat Covid-19 aggravated by poorly controlled Diabetes Melitus Type 2
Toward to understanding the mechanism of NAD+ (NADH) and NADP+ (NADPH) aqueous solution high-temperature fluorescence
Expression of Concern: Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats
NAD+ Flux and Resiliency in Aged Mice
Inhibition of epithelial phosphate transport by NAD+/NADH.
Use of NAD-Seq to Profile NAD+-Capped RNAs in Plants
Investigation of the role of PARP-1 and CD38 in modulating NAD+ levels in spinal and bulbar muscular atrophy
Senescence Effect on Gastric Parietal Cells in Male Albino Rats and the Impact of Nicotinamide Riboside (a NAD+ Precursor): Histological Study
Emerging Roles of Sirtuins in Chromatin Regulation and DNA Repair via their NAD+-dependent Activities
Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge
Mechanisms of Protection in Early and Mid‐Stage Alzheimer’s Disease by Treatment with NAD+ Preserving Compound
… BONE FORMATIONVIA THE SIGNAL TRANSDUCTION NETWORK BETWEEN THE CELLULAR ENERGY SENSOR, NAD+-DEPENDENT DEACETYLASE (SIRTUIN1 …
Modulation of NAD+/NADH Levels in ARPE-19 Cells Leads to Functional Changes in Oxidative Phosphorylation and Glycolysis
NAMPT as a Dedifferentiation-Inducer NAD+ as Core Axis for Glioma Gene: Cancer Stem-Like Cells Maintenance
Saito Tand Tsuge K (2019) A Novel Photo-Driven Hydrogenation Reaction of an NAD+-Type Complex Toward Artificial Photosynthesis
… and Metabolic Diseases: Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in …
NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing
Period 3 regulates mitochondrial function via the NAD+-SIRT3 axis in mice
Monomeric Proanthocyanidins Increase Intracellular NAD+ Content by Enhancing NAMPT Transcription
Structural mechanism of NAD+ cleavage by plant TIR domain
Cytoplasmic NAD+inhibits mRNA translation in ovarian cancers
Structure-based design of NAD+ analogues targeting bacterial NAD kinases, promising targets for new antibiotics
Research progress on the role of NAD+ metabolism in cell function and related-diseases
Case Report 1: NAD+ Oscillation Therapy (NOT) to treat Covid-19 aggravated by poorly controlled Diabetes Melitus Type 2
Glucocorticoid Excess Disrupts the NAD+ Metabolome Within Skeletal Muscle in Male and Female C57BL/6J Mice
MP38-02 IMPAIRED NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD+) MEDIATING ENDOTHELIUM-INDEPENDENT RELAXATION WITH AGING ON HUMAN …
NAD+: a crucial regulator of sirtuin activity in aging
Boosting cellular NAD+ concentration with nicotinamide mononucleotide prevents Doxorubicin-induced cardiotoxicity
Regulation of Sirtuin NAD+-dependent Deacylase Activity by Cellular Oxidants
Observational evidence of NAD+ biosynthetic impairment and urinary metabolomic alterations in covid-related AKI
Targeting mitochondrial bioenergetics and NAD+ metabolism during sarcopenia and regeneration of skeletal muscle
TAMI-30. LOCAL TARGETING OF NAD+ SALVAGE PATHWAY ALTERS THE IMMUNE TUMOR MICROENVIRONMENT AND ENHANCES CHECKPOINT …
Serotonin-Induced Vasoconstriction Mediated by NAD+ as a Therapy for Bleeding Disorders
Investigating photosynthesis by in planta ATP, NADPH and NADH/NAD+ sensors
Exploration of gene therapies targeting oxidative stress and NAD+ pathways for the treatment of optic neuropathy
Investigation of neuroprotection by NAD+ in response to deep space radiation
Nutritional Strategies to Counteract Mitochondrial Dysfunction and NAD+ Deficiency in Human Sarcopenia
Electrochemical Structure-Reactivity Relationships in NAD+ Mimetics: Towards Recyclable Cofactors for Protein-Catalyzed Reactions
Gene Regulation in Saccharomyces cerevisiae: the role of NAD+ metabolism and non-coding RNAs in protein-coding genes
Sirtuins as NAD+-dependent deacetylases and their potential in medical therapy
Quantitative Survey of NAD+ Flux in Aged Mice
NAD+ ux is maintained in aged mice
Modeling age-related alterations in the mouse liver circadian clock caused by an imbalance in the NAD+ consumption system
Corrigendum to” Increasing ovarian NAD+ levels improve mitochondrial functions and reverse ovarian aging”[Free Rad. Biol. Med. 156C (2020) 1-10]
Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal myopathy of H6PDH KO mice
Dietary proanthocyanidins boost hepatic NAD+ metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats
Partially Conserved Motifs Support an Alternating Access Model for the Human Mitochondrial NAD+ Transporter
Comparison of mitochondria and NAD+ level in the murine cochleae of C57BL/6J mice at different ages
NAD+ metabolism as a novel target against infection–Volume II
NMNAT3 improves mitochondrial function and enhances BMSCs anti-oxidative stress through the NAD+-Sirt3 pathway
… identify quinolate phosphoribosyltransferase as a key mediator of acquired resistance to Panobinostat and Bortezomib in glioma, and NAD+ biosynthesis as a …
Enabling Characterisation of the NAD+ Biosynthesis Pathway via in vitro CEST MRI
The NAD+-dependent deacetylase Sir2 enables evolution of new traits by regulating distinct gene sets in two yeast species, Saccharomyces cerevisiae and …
Understanding NAD+ metabolism and regulation by N-terminal acetylation
A System of Photocatalysis for NAD+ Regeneration of Product of (S)-1-Pheylethanol by Enzymic Catalysis
NAD+, NR, and NMN: Longevity and Genes
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons
An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD+ and Disulfiram.
Healthy aging and muscle function are positively associated with NAD+ abundance in humans
Age-related alterations in the mouse liver circadian clock are caused by an imbalance of the NAD+ consumption system
Modeling the influence of the availability of NAD+ for the SIRT1 enzyme on the interaction of the circadian oscillator with the inflammatory response system to …
Depleting NAD+ pools specifically in the endoplasmic reticulum lumen impairs 11 [beta]-hydroxysteroid dehydrogenase activity
Structure of NAD+ consuming Acinetobacter baumannii TIR domain.
NAD+ prevents septic shock by non-canonical inflammasome blockade
P–230 The NAD+ precursor nicotinamide riboside protects against postovulatary aging in vitro
Fatty acids getting NAD+ about cardiometabolic diseases
NAD+ and aging: a focus on novel molecular mechanisms of werner syndrome
Dietary Supplementation with NAD+ Precursors to Support Exercise: An Evaluation of the Clinical Evidence
AhR-NQO1 Signaling in Hepatocytes Drives a Protective Response against Alcohol-induced NAD+ Depletion and Liver Damage
NAD+-dependent deacetylase SIRT1 is essential for meiotic progression and controls repair-recombination efficiency
The Role of NAD+ in Rejuvenating Human Body
NAD+ Supplementation Improves the Productivity of Therapeutic Antibodies by Reducing Inefficient Glycolysis in CHO Cells
Efficacy and safety of NAD+ ADP-ribosyltransferase 1 agonist versus Donepezil in elderly Chinese patients with Alzheimer disease: A novel target for effective therapy.
Aerobic and Resistance Exercise Training Reverses Age-Dependent Decline in NAD+ Salvage Capacity in Human skeletal muscle
Correction: The catalytic mechanism of electron-bifurcating electron transfer flavoproteins (ETFs) involves an intermediary complex with NAD+.
A Method of Lactate Assay Based on NAD+/NADH Fluorescent Sensor
Prognostic Signature of NAD+ Metabolism-Related lncRNAs in Glioma Patients
Loss of NAMPT and decreased NAD+ levels contributes to stress-associated premature senescence (SAPS) in the diabetic retinal microvasculature
Preliminary data show Normal Tension Glaucoma patients have lower systemic nicotinamide adenine dinucleotide (NAD+) levels and mitochondrial function …
Assessment of the Peroxisomal Redox State in Living Cells Using NADPH-and NAD+/NADH-Specific Fluorescent Protein Sensors
On the effects of Streptococcal NAD+-glycohydrolase and Streptolysin O on macrophages
Role of NAD+-mediated deacetylation activity of SIRT1 in endotoxin-induced acute lung injury in mice
NAD+ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy
Mechanisms Behind the Regulation of NAD+ by the Ischemic Neuroprotectants PKC Epsilon and Resveratrol
targeting NAD+ Metabolism as Interventions for Mitochondrial
… cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of …
The Powerful Roles of NAD+ in Anti-Aging
… Mixture from Panax Ginseng CA Meyer Improves CoCl2-Induced Oxidative Stress and Mitochondrial Dysfunction Through NAD+-Dependent SIRT1 Activation in …
P6281 Over expression of HINT2 preserves the mitochondria function of cardiomyocytes via regulating the NAD+ homeostasis
Effects of oxidized coenzyme NAD+ and SahH active site on catalytic activity of Brucella SahH.
Role of mitochondria in diabetic peripheral Influencing neuropathy: the NAD+-dependent SIRT1–PGC-1α–TFAM pathway
Nicotinamide Restores Tissue NAD+ and Improves Mouse Survival After Cardiac Arrest
Characterization of SIP428: a NAD+-Dependent Deacetylase Enzyme, in Abiotic Stress.
NMNAT1-Associated Retinal Degeneration: Consequences of Reduced Nuclear NAD+ Production
The Synthesis of the Vitamin B3 Derivatives for Modulation NAD+ Biosynthetic Pathways
Characterization of new molecules and enzymes involved in the regulation of NAD+ levels
… and Glomerular and Tubulointerstitial Injury in Mutant Mice With Kidney Proximal Tubule‐selective Deletion of Mitochondrial NAD+‐dependent Deacetylase Sirtuin 3 …
Non-adiabatic quantum dynamical studies of Na (3p)+ HD (v= 1, j5)= 0)→ NaH/NAD+ D/H reaction
NAD+ Supplement Potentiates Tumor Killing Function by Rescuing Defective Tubby-Mediated NAMPT Transcription in Tumor Infiltrated T Cells
Bacillus amyloliquefaciens NAD+-dependent protein deacetylase: purification, crystallization and X-ray crystallographic analysis
Characterization of SABP2-Interacting Proteins (SIP) 428: an NAD+-Dependent Deacetylase Enzyme in Plant Abiotic Stress Signaling
Importance of NAD+ and Boosting Strategies via Targeting NAD+ Pathway Genes
Enzymatic production of acetaldehyde using a Pseudomonas fluorescens mannitol‐2‐dehydrogenase mutant to regenerate NAD+
Results-III. SIRT6 Is an Acetylated Protein and a NAD+-Dependent Self-deacetylase
Increasing NAD+ levels through nicotinamide riboside activates in vivo brown adipose tissue in mice but not in humans
Pseudomonas fluorescens Mannitol‐2‐Dehydrogenase as an NAD+ Recycling Enzyme in the Conversion of Ethanol to Acetaldehyde
Mechanisms and Effects of NAD+ Modulation in Inflammation and Aging
CBMS-01 AGE-DEPENDENT GLIOBLASTOMA PROGRESSION SUPPRESSED BY NAD+
2590. Streptolysin O Enhances Binding of the Group A Streptococcal NAD+-Glycohydrolase Toxin to Oropharyngeal Keratinocytes.
MON-162 Hepatic DNA Damage Induced by ENDS Is Associated with Decreased Levels of NAD+
NAD+ Repletion Reverses HFpEF by Attenuating Myocardial Metabolic Dysfunction
transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD+ in medium-chain acyl-coA dehydrogenase knockout mice
Cofactor switch: Development of A NAD+-dependent cascade for the production of ursodeoxycholic acid (UDCA)
… BY TARGETING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT), THE RATE-LIMITING ENZYME OF NAD+ SALVAGE PATHWAY INCREASES …
Bacillus amyloliquefaciens NAD+-dependent protein deacetylase: purification, crystallization and X-ray crystallographic analysis
NAD+ Redox Imbalance Exacerbates Diabetic Cardiomyopathy via Enhanced Troponin I Phosphorylation, Impaired Energetics and Prolonged Cardiac Relaxation
Characterization of a Human Dihydrolipoamide Dehydrogenase Mutant Showing Significantly Decreased Catalytic Efficiency toward NAD+
Corrigendum: Qualitative and Quantitative NAD+ Metabolomics Lead to Discovery of Multiple Functional Nicotinate N-Glycosyltransferase In Arabidopsis
Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors [Cardiovasc Res 2014 …
M. tuberculosis class II apurinic/apyrimidinic‐endonuclease/3′‐5′ exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile …
High Production of 4-hydroxyvalerate by Coexpressing a 3HBDH Mutant and a NAD+-dependent Formate Dehydrogenase in Escherichia coli.
Maintenance of mammalian oocyte quality and fertility during ageing via Sirtuin activity and NAD+ repletion
NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
4.8 Malate Dehydrogenase (Oxaloacetate‐Decarboxylating)(NAD+), EC 1.1. 1.38, and Malate Dehydrogenase (Decarboxylating), EC 1.1. 1.39
Correction: Kinetics and structural features of dimeric glutamine-dependent bacterial NAD+ synthetases suggest evolutionary adaptation to available metabolites.
Supplementary materials MV Makarov, NW Harris, M. Rodrigues, and ME Migaud Manuscript title:“Scalable syntheses of traceable ribosylated NAD+ precursors …
Muscle‐Specific Over‐Expression of the NAD+‐Dependent Nuclear Sirtuin SIRT6, Suppresses Cancer‐Associated Cachexia
Nadidum (NADH) Nicotinamide adenine dinucleotide, NAD+, Nadide, Coenzyme 1, Coenzyme B3
formation and of the structure of enzyme-NAD+-product com—
Integrating RNA-seq and scRNA-seq to explore the biological significance of NAD+ metabolism-related genes in the initial diagnosis and relapse of childhood B-cell …
NAD+ Homeostasis and NAD+-Consuming Enzymes: Implications for Vascular Health
The central role of the NAD+ molecule in the development of aging and the prevention of chronic age-related diseases: strategies for NAD+ modulation
Pangenomic analysis reveals plant NAD+ manipulation as an important virulence activity of bacterial pathogen effectors
NAD+ metabolism-based immunoregulation and therapeutic potential
A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD+ metabolism
NAD+ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling
NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury
NAD+ repletion with niacin counteracts cancer cachexia
Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity
Early loss of endogenous NAD+ following rotenone treatment leads to mitochondrial dysfunction and Sarm1 induction that is ameliorated by PARP inhibition
In silico protein engineering shows that novel mutations affecting NAD+ binding sites may improve phosphite dehydrogenase stability and activity
Biotechnological production of reduced and oxidized NAD+ precursors
Time-of-day defines NAD+ efficacy to treat diet-induced metabolic disease by synchronizing the hepatic clock in mice
Doped Graphene To Mimic the Bacterial NADH Oxidase for One-Step NAD+ Supplementation in Mammals
Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory–entorhinal–amygdaloid axis in Alzheimer’s and Parkinson’s …
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice
Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD+/SIRT1 axis
Structure-based investigations of the NAD+-II riboswitch
Visible-light driven enantioselective L-lactate synthesis with a combination system of biocatalyst and dye-sensitized NAD+ reduction
Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation
Mrhst4 gene, coding for NAD+-dependent deacetylase is involved in citrinin production of Monascus ruber
Preclinical characterization of pharmacological NAD+ boosting as a promising therapeutic approach in Rheumatoid Arthritis
Ratiometric NAD+ Sensors Reveal Subcellular NAD+ Modulators
The acute effect of different NAD+ precursors included in the combined metabolic activators
Colonic mechanism of serum NAD+ depletion induced by DEHP during pregnancy
Metabolomic analysis shows dysregulation in amino acid and NAD+ metabolism in palmitate treated hepatocytes and plasma of non-alcoholic fatty liver disease …
Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population
Coupled immobilized bi-enzymatic flow reactor employing cofactor regeneration of NAD+ using a thermophilic aldehyde dehydrogenase and lactate …
NAD+ and mtRNA sensing drive human kidney diseases
Neuroprotection of NAD+ and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis
Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Crystal structures of the NAD+-II riboswitch reveal two distinct ligand-binding pockets
Dietary supplementation with NAD +-boosting compounds in humans: Current knowledge and future directions
Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF‐1α
Targeting NAD+ regeneration enhances antibiotic susceptibility of Streptococcus pneumoniae during invasive disease
β-Nicotinamide mononucleotide activates NAD+/SIRT1 pathway and attenuates inflammatory and oxidative responses in the hippocampus regions of septic …
NAD+ precursor nutritional supplements sensitize the brain to future ischemic events
Structure‐based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase
STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes
Photoinduced Catalytic Organic‐Hydride Transfer to CO2 Mediated with Ruthenium Complexes as NAD+/NADH Redox Couple Models**
The Histone Deacetylases Hst1 and Rpd3 Integrate De Novo NAD+ Metabolism with Phosphate Sensing in Saccharomyces cerevisiae
NAD+-Consuming Enzymes in Stem Cell Homeostasis
P7C3-A20 Attenuates Microglial Inflammation and Brain Injury after ICH through Activating the NAD+/Sirt3 Pathway
A prognostic NAD+ metabolism-related gene signature for predicting response to immune checkpoint inhibitor in glioma
Nicotinamide adenine dinucleotide (NAD+)-dependent signaling in neurological disorders
Quantification of localized NAD+ changes reveals unique specificity of NAD+ regulation in the hypothalamus
Comprehensive Proteomics Analysis Identifies CD38-Mediated NAD+ Decline Orchestrating Renal Fibrosis in Pediatric Patients With Obstructive …
Assessment of the Peroxisomal Redox State in Living Cells Using NADPH- and NAD+/NADH-Specific Fluorescent Protein Sensors
Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD+
Therapeutic application of natural products: NAD+ metabolism as potential target
Tissue‐specific effects of exercise as NAD+‐boosting strategy: Current knowledge and future perspectives
NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia–reperfusion injury
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents
NAD+ supplementation improves mAb productivity in CHO cells via a glucose metabolic shift
NAD+ Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan
Involvement of SlSTOP1 regulated SlFDH expression in aluminum tolerance by reducing NAD+ to NADH in the tomato root apex
Association of NAD+ levels with metabolic disease in a community-based study
NAD+ Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies
Bioorganometallic Chemistry at the Interface with Biocatalysis: Chemoselective Reduction of Biomimetic NAD+ Cofactors with [Cp*Rh(bpy)H]+, Tandem Catalysis …
Interactions between Intestinal Homeostasis and NAD+ Biology in Regulating Incretin Production and Postprandial Glucose Metabolism
ATP and NAD+ Deficiency in Parkinson’s Disease
… mononucleotide (NMN) ameliorated Nonylphenol-induced learning and memory impairment in rats via the central 5-HT system and the NAD+/SIRT1/MAO-A pathway
The role of NAD+ metabolism in macrophages in age-related macular degeneration
The Role of NAD+, SIRTs Interactions in Stimulating and Counteracting Carcinogenesis
Epigenetic drug library screening reveals targeting DOT1L abrogates NAD+ synthesis by reprogramming H3K79 methylation in uveal melanoma
Regioselective Reduction of NAD+ to 1,4‐NADH with a Bioinspired Metal Sulfide Electrocatalyst
Nicotinamide adenine dinucleotide (NAD+) reduction enabled by an atomically precise Au-Ag alloy nanocluster
The metabolites of de novo NAD+ synthesis are a valuable predictor of acute kidney injury
Nicotinamide Phosphoribosyltransferase‐elevated NAD+ biosynthesis prevents muscle disuse atrophy by reversing mitochondrial dysfunction
Targeting NAD+ metabolism of hepatocellular carcinoma cells by lenvatinib promotes M2 macrophages reverse polarization, suppressing the HCC progression
Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD+/SIRT3 pathway
Hepatic mitochondrial NAD+ transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis
NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders
Cp* non-innocence and the implications of (η4-Cp* H) Rh intermediates in hydrogenation of CO2, NAD+, amino-borane, and the Cp* framework–a computational …
Impact of Sodium Pyruvate on the Electrochemical Reduction of NAD+ Biomimetics
Mechanism of CD38 via NAD+ in the Development of Non-alcoholic Fatty Liver Disease
NAD+ Biosynthesis Impairment and Acute Kidney Injury after Major Vascular Surgery
Development of prognostic indicator based on NAD+ metabolism related genes in glioma
Tetraphenylethene-linked octacationic dicyclophanes with enhanced recognition of NADH over NAD+ in water
NAD+ enhances the activity and thermostability of S-adenosyl-L-homocysteine hydrolase from Pyrococcus horikoshii OT3
PM2.5 mediates mouse testis Sertoli TM4 cell damage by reducing cellular NAD+
CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD+-Sirt1-PGC1α signaling pathway
Identification of new resonances in downfield 1H MRS of human calf muscle in vivo: Potentially metabolite precursors for skeletal muscle NAD+
NAD+ Synthetase is Required for Free-living and Symbiotic Nitrogen Fixation in the Actinobacterium Frankia casuarinae
Turning up the NAD+-mitophagy axis to treat Alzheimer’s disease
Fingerstick blood assay maps real-world NAD+ disparity across gender and age
Application of NAD+-Dependent Electrochemical Dehydrogenase Biosensors in Human Physiological Fluids: Opportunities and Challenges
Evaluation of Antibacterial Activity of Thiourea Derivative TD4 against Methicillin-Resistant Staphylococcus aureus via Destroying the NAD+/NADH …
Organ protection by caloric restriction depends on activation of the de novo NAD+ synthesis pathway
Cystathionine gamma lyase overexpression modulates NAD+ biosynthesis and enhances neovascularization
Synthesis, Characterization and Structural Studies of Novel Pyrazoline Derivatives as Potential Inhibitors of NAD+ Synthetase in Bacteria and Cytochrome P450 51 in …
The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
Mid-infrared Photons Released by NAD+ Reduction in the Tricarboxylic Acid Cycle of Myelinated Neuron
Genistein enhances NAD+ biosynthesis by binding to Prohibitin 1 and upregulating nicotinamide phosphoribosyltransferase in adipocytes
POS1038 NAD+ BOOSTERS AS A NOVEL ANTI-INFLAMMATORY TOOL IN RHEUMATOID ARTHRITIS PATIENTS
PROLINE SYNTHESIS THROUGH PYCR1/NAD+/SIRT7 AXIS-MEDIATED MITOCHONDRIAL-TONUCLEAR COMMUNICATION IS REQUIRED FOR CARDIAC …
CD38 regulates ovarian function and fecundity via NAD+ metabolism
NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections
NAD+ administration profoundly decreases UVC-induced skin damage by attenuating oxidative stress, inflammation, DNA damage and apoptosis
Elevation of NAD+ by nicotinamide riboside spares spinal cord tissue from injury and promotes locomotor recovery
Circulating factors in plasma from patients with COVID-19 cause endothelial cell dysfunction, oxidative stress and NAD+ depletion: prevention by nicotinamide …
A dual MTOR/NAD+ acting gerotherapy
Association Of Sustained Systemic NAD+ Levels With Protective Effect Of Cd38 Deficiency In A Post-Traumatic Oa Model In Mice
… BONE FORMATION VIA THE SIGNAL TRANSDUCTION NETWORK OF CELLULAR ENERGY SENSOR, NAD+-DEPENDENT DEACETYLASE (SIRTUIN 1) AND …
Structure-activity studies of 1, 2, 4-oxadiazoles for the inhibition of the NAD+ dependent lysine deacylase Sirtuin2
Pharmacology of NAD+ boosters
Supplementation of nicotinic acid and its derivatives up-regulates cellular NAD+ level rather than nicotinamide derivatives in cultured normal human epidermal …
Non-canonical and distinct necrosis mechanism in two cell types in a Caenorhabditis elegans NAD+ salvage pathway mutant
Construction of a prognostic model for gastric cancer patients based on NAD+ metabolism-related genes and tumor microenvironment analysis
Nutraceuticals for targeting NAD+ to restore mitochondrial function
Correction for Taniguchi et al., “A Key Enzyme of the NAD+ Salvage Pathway in Thermus thermophilus: Characterization of Nicotinamidase and the Impact of Its Gene …
NAD+ Consuming Enzymes: Involvement in Therapies and Prevention of Human Diseases.
Exploring the Physiological Effects of Altering NAD+ Biosynthesis in NMNAT Transgenic Mice
Structural basis for the recruitment of PARP4 and NAD+ to the vault complex
NAD+ DEPLETION IN THE INTESTINAL EPITHELIUM RESULTS IN MITOCHONDRIAL DYSFUNCTION AND INFLUENCES THE PATHOGENESIS OF …
Comprehensive investigation of the role of CD38 in ovarian NAD+ metabolism and reproductive aging
New therapeutic strategies suppressing NAD+ and ATP production in cancer metabolism specific to 3D cultured ovarian cancer cells
Enzymatic Electro-reduction of Carbon Dioxide to Formate by Directly Immobilized NAD+-independent Formate Dehydrogenase
Understanding the role of SABP2-interacting proteins (SIP) 428: an NAD+-Dependent Deacetylase Enzyme in Abiotic Stress Signaling of Nicotiana tabacum
… hereditary enamel hypoplasia. Silence information regulator 2-related enzyme 1 (Sirt1) is a nicotinamide adenosine dinucleotide (NAD+)-dependent deacetylase that …
The immunomodulatory role of IDO1-Kynurenine-NAD+ pathway in switching cold tumor microenvironment in PDAC
NAD+ biosynthesis metabolism predicts prognosis and indicates immune microenvironment for breast cancer
Understanding the roles of SIP428, a NAD+ dependent deacetylase enzyme in mediating abiotic stress signaling in Nicotiana tabacum
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