Insulin & Mtor

  1. mTorโ€dependent stimulation of the association of eIF4G and eIF3 byย insulin
  2. insulinย signalling toย mTorย mediated by the Akt/PKB substrate PRAS40
  3. The role of mammalian target of rapamycin (mTor) inย insulinย signaling
  4. Amino acid andย insulinย signaling via theย mTor/p70 S6 kinase pathway: a negative feedback mechanism leading toย insulinย resistance in skeletal muscle cells
  5. The cardioprotection of theย insulin-mediated PI3K/Akt/mTorย signaling pathway
  6. Downโ€regulation of placentalย mTor,ย insulin/IGFโ€I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon
  7. Judicious toggling ofย mTorย activity to combatย insulinย resistance and cancer: current evidence and perspectives
  8. Akt/mTorย role in human foetoplacental vascularย insulinย resistance in diseases of pregnancy
  9. Amino acids andย insulinย control autophagic proteolysis through different signaling pathways in relation toย mTorย in isolated rat hepatocytes
  10. Activation of mammalian target of rapamycin (mTor) byย insulinย is associated with stimulation of 4EBP1 binding to dimericย mTorย complex 1
  11. Stimulation of theย insulin/mTorย pathway delays cone death in a mouse model of retinitis pigmentosa
  12. insulinย activation of Rheb, a mediator ofย mTor/S6K/4E-BP signaling, is inhibited by TSC1 and 2
  13. MAP kinases andย mTorย mediateย insulin-induced phosphorylation ofย insulinย receptor substrate-1 on serine residues 307, 612 and 632
  14. insulinย and amino-acid regulation ofย mTorย signaling and kinase activity through the Rheb GTPase
  15. Glycerolipid signals alterย mTorย complex 2 (mTorC2) to diminishย insulinย signaling
  16. Acuteย mTorย inhibition inducesย insulinย resistance and alters substrate utilization in vivo
  17. IKKฮฒ suppression of TSC1 function links theย mTorย pathway withย insulinย resistance
  18. Chronicย mTorย inhibition by rapamycin induces muscleย insulinย resistance despite weight loss in rats
  19. insulinย stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTor-NFฮบB-Opa-1 signaling pathway
  20. insulin-and leptin-mediated control of aquaglyceroporins in human adipocytes and hepatocytes is mediated via the PI3K/Akt/mTorย signaling cascade
  21. Longโ€chain omegaโ€3 fatty acids regulate bovine wholeโ€body protein metabolism by promoting muscleย insulinย signalling to the Aktโ€“mTorโ€“S6K1 pathway andย insulinย โ€ฆ
  22. Inappropriate activation of the TSC/Rheb/mTor/S6K cassette induces IRS1/2 depletion,ย insulinย resistance, and cell survival deficiencies
  23. Distinct signaling events downstream ofย mTorย cooperate to mediate the effects of amino acids andย insulinย on initiation factor 4E-binding proteins
  24. insulinย promotes dendritic spine and synapse formation by the PI3K/Akt/mTorย and Rac1 signaling pathways
  25. Glucose phosphorylation is required forย insulin-dependentย mTorย signalling in the heart
  26. Quantification of the effect of amino acids on an integratedย mTorย andย insulinย signaling pathway
  27. โ€ฆ 3-kinase/Akt/mTorย pathway mediates and PTEN antagonizes tumor necrosis factor inhibition ofย insulinย signaling throughย insulinย receptor substrate-1
  28. Adipocyte-specific deletion ofย mTorย inhibits adipose tissue development and causesย insulinย resistance in mice
  29. Mammalian target of rapamycin (mTor) is involved in the neuronal differentiation of neural progenitors induced byย insulin
  30. mTorC2 promotes type Iย insulin-like growth factor receptor andย insulinย receptor activation through the tyrosine kinase activity ofย mTor
  31. Activation ofย mTor/p70S6 kinase by ANG II inhibitsย insulin-stimulated endothelial nitric oxide synthase and vasodilation
  32. Protein ingestion induces muscleย insulinย resistance independent of leucine-mediatedย mTorย activation
  33. Leucine deprivation increases hepaticย insulinย sensitivity via GCN2/mTor/S6K1 and AMPK pathways
  34. The PI3K/Akt/mTorย signaling pathway mediatesย insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells
  35. Longevity pathways (mTor, SIRT,ย insulin/IGF-1) as key modulatory targets on aging and neurodegeneration
  36. The TSC-mTorย pathway mediates translational activation of TOP mRNAs byย insulinย largely in a raptor-or rictor-independent manner
  37. Amino acids are necessary for theย insulin-induced activation ofย mTor/S6K1 signaling and protein synthesis in healthy andย insulinย resistant human skeletal muscle
  38. Genetically reducingย mTorย signaling rescues centralย insulinย dysregulation in a mouse model of Alzheimerโ€™s disease
  39. Theย insulin-like growth factor-Iโ€“mTorย signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth
  40. mTorย complex 2 regulates proper turnover ofย insulinย receptor substrate-1 via the ubiquitin ligase subunit Fbw8
  41. insulin-like growth factor II targets theย mTorย pathway to reverse autism-like phenotypes in mice
  42. mTorย inhibition with rapamycin causes impairedย insulinย signalling and glucose uptake in human subcutaneous and omental adipocytes
  43. Hepatitis C virus activates theย mTor/S6K1 signaling pathway in inhibiting IRS-1 function forย insulinย resistance
  44. Activation of placentalย insulinย andย mTorย signaling in a mouse model of maternal obesity associated with fetal overgrowth
  45. Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependentย mTor-mediatedย insulinย receptor substrate 1 phosphorylation
  46. mTorย and neuronal cell cycle reentry: how impaired brainย insulinย signaling promotes Alzheimerโ€™s disease
  47. Zinc stimulates the activity of theย insulin-and nutrient-regulated protein kinaseย mTor
  48. insulinย growth factor-receptor (IGF-1R) antibody cixutumumab combined with theย mTorย inhibitor temsirolimus in patients with refractory Ewingโ€™s sarcoma family โ€ฆ
  49. Exercise training reducesย insulinย resistance and upregulates theย mTor/p70S6k pathway in cardiac muscle of dietโ€induced obesity rats
  50. insulin-and lipopolysaccharide-mediated signaling in adipose tissue macrophages regulates postprandial glycemia through akt-mTorย activation
  51. Maternal protein restriction in the rat inhibits placentalย insulin,ย mTor, and STAT3 signaling and down-regulates placental amino acid transporters
  52. Glucose induces mouse ฮฒ-cell proliferation via IRS2,ย mTor, and cyclin D2 but not theย insulinย receptor
  53. hNAG-1 increases lifespan by regulating energy metabolism andย insulin/IGF-1/mTorย signaling
  54. Effects ofย insulinย and pathway inhibitors on the PI3K-Akt-mTorย phosphorylation profile in acute myeloid leukemia cells
  55. Statins activate the NLRP3 inflammasome and impairย insulinย signaling via p38 andย mTor
  56. Enhanced skeletal muscleย insulinย sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitiveย mTorย complex 1 inhibition
  57. Excitotoxic glutamate causes neuronalย insulinย resistance by inhibitingย insulinย receptor/Akt/mTorย pathway
  58. Overexpression of kinase-deadย mTorย impairs glucose homeostasis by regulatingย insulinย secretion and not ฮฒ-cell mass
  59. Regulation ofย insulinย signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and theย mTor/p70 S6K pathway
  60. insulinย growth factor receptor (IGF-1R) antibody cixutumumab combined with theย mTorย inhibitor temsirolimus in patients with metastatic adrenocortical โ€ฆ
  61. Role of the PI3-kinase/mTorย pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression byย insulinย in liver
  62. Inhibition of theย mTor/p70S6K pathway is not involved in theย insulin-sensitizing effect of AMPK on cardiac glucose uptake
  63. insulin-like growth factor I-mediated skeletal muscle hypertrophy is characterized by increasedย mTor-p70S6K signaling without increased Akt phosphorylation
  64. Mammalian target of rapamycin (mTor) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulatingย insulin-like growth factor-1 receptor signaling in acute โ€ฆ
  65. A novel voluntary weightlifting model in mice promotes muscle adaptation andย insulinย sensitivity with simultaneous enhancement of autophagy andย mTorย pathway
  66. Mechanistic target of rapamycin (mTor): a point of convergence in the action ofย insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer โ€ฆ
  67. insulinย promotes glucose consumption via regulation of miR-99a/mTor/PKM2 pathway
  68. Salmonella enterica Typhimurium infection causes metabolic changes in chicken muscle involving AMPK, fatty acid andย insulin/mTorย signaling
  69. Systematic Screen for Drosophila Transcriptional Regulators Phosphorylated in Response toย insulin/mTorย Pathway
  70. insulinย andย mTorย pathway regulate HDAC3-mediated deacetylation and activation of PGK1
  71. The role of AMPK/mTor/S6K1 signaling axis in mediating the physiological process of exercise-inducedย insulinย sensitization in skeletal muscle of C57BL/6 โ€ฆ
  72. The regulation of lipid deposition byย insulinย in goose liver cells is mediated by the PI3K-AKT-mTorย signaling pathway
  73. Amino acids and leucine allowย insulinย activation of the PKB/mTorย pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice
  74. Anthocyanin-rich mulberry fruit improvesย insulinย resistance and protects hepatocytes against oxidative stress during hyperglycemia by regulating AMPK/ACC/mTorย โ€ฆ
  75. Both Wnt andย mTorย signaling pathways are involved inย insulin-stimulated proto-oncogene expression in intestinal cells
  76. Palmitate inducedย insulinย resistance by PKCtheta-dependent activation ofย mTor/S6K pathway in C2C12 myotubes
  77. insulin-like peptides and theย mTor-TFEB pathway protect Caenorhabditis elegans hermaphrodites from mating-induced death
  78. PKCฮถ is essential for pancreatic ฮฒ-cell replication duringย insulinย resistance by regulatingย mTorย and cyclin-D2
  79. Akt/mTorย Counteract the Antitumor Activities of Cixutumumab, an Anti-insulinโ€“like Growth Factor I Receptor Monoclonal Antibody
  80. insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K โ€ฆ
  81. mTor-Independent autophagy inducer trehalose rescues againstย insulinย resistance-induced myocardial contractile anomalies: Role of p38 MAPK and Foxo1
  82. Leucine activates pancreatic translational machinery in rats and mice throughย mTorย independently of CCK andย insulin
  83. insulinย regulates titin pre-mRNA splicing through the PI3K-Akt-mTorย kinase axis in a RBM20-dependent manner
  84. insulinย fails to enhanceย mTorย phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement
  85. insulinย receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTor)-induced negative feedback down-regulates โ€ฆ
  86. Exercise and dietary change ameliorate high fat diet induced obesity andย insulinย resistance viaย mTorย signaling pathway
  87. insulin-induced de novo lipid synthesis occurs mainly viaย mTor-dependent regulation of proteostasis of SREBP-1c
  88. Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-inducedย insulinย resistance by the enhanced association ofย mTorย and rictor
  89. โ€ฆ a model describing regulation of casein synthesis by the mammalian target of rapamycin (mTor) signaling pathway in response toย insulin, amino acids, and โ€ฆ
  90. โ€ฆ hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTor) and c-Jun N-terminal kinase/insulinย receptor substrate 1 โ€ฆ
  91. Antiproliferation of cardamonin is involved inย mTorย on aortic smooth muscle cells in high fructose-inducedย insulinย resistance rats
  92. THE ROLE OF AMPK ANDย mTorย IN THE DEVELOPMENTOFย insulinย RESISTANCE AND TYPE 2 DIABETES. THE MECHANISM OF METFORMIN ACTION โ€ฆ
  93. Nanocurcumin alleviatesย insulinย resistance and pancreatic deficits in polycystic ovary syndrome rats: Insights on PI3K/AkT/mTorย and TNF-ฮฑ modulations
  94. insulinย stimulates goose liver cell growth by activating PI3K-AKT-mTorย signal pathway
  95. insulin-like growth factor 1 receptor-mediated cell survival in hypoxia depends on the promotion of autophagy via suppression of the PI3K/Akt/mTorย signaling โ€ฆ
  96. Zinc stimulates glucose consumption by modulating theย insulinย signaling pathway in L6 myotubes: essential roles of Aktโ€“GLUT4, GSK3ฮฒ andย mTorโ€“S6K1
  97. Leucine stimulatesย insulinย secretion via down-regulation of surface expression of adrenergic ฮฑ2A receptor through theย mTorย (mammalian target of rapamycin โ€ฆ
  98. Activation of the PI3K/Akt/mTor/p70S6K1 signaling cascade in the mononuclear cells of peripheral blood: association withย insulinย andย insulin-like growth factor levels โ€ฆ
  99. Effective amelioration of hepatic inflammation andย insulinย response in high fat diet-fed rats via regulating AKT/mTorย signaling: Role of Lepidium sativum seed extracts
  100. 17ฮฒ-estradiol regulates glucose metabolism andย insulinย secretion in rat islet ฮฒ cells through GPER and Akt/mTor/GLUT2 pathway
  101. Therapeutic effects of organic zinc on reproductive hormones,ย insulinย resistance andย mTorย expression, as a novel component, in a rat model of Polycystic โ€ฆ
  102. Cardamonin amelioratesย insulinย resistance induced by highย insulinย and high glucose through theย mTorย and signal pathway
  103. Inhibitingย insulinย andย mTorย signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma
  104. Implication of RICTOR in theย mTorย inhibitor-mediated induction ofย insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 โ€ฆ
  105. Humanin attenuates palmitate-induced hepatic lipid accumulation andย insulinย resistance via AMPK-mediated suppression of theย mTorย pathway
  106. โ€ฆ ofย insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: roles of Akt,ย mTor, GSK3ฮฒ, and PTEN
  107. insulin-induced serine phosphorylation of IRS-2 via ERK1/2 andย mTor: studies on the function of Ser675 and Ser907
  108. Pectic bee pollen polysaccharide from Rosa rugosa alleviates diet-induced hepatic steatosis andย insulinย resistance via induction of AMPK/mTor-mediated autophagy
  109. Evodiamine inhibitsย insulin-stimulatedย mTor-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese โ€ฆ
  110. โ€ฆ improves vascular endothelial dysfunction by inducing autophagy via AMPK/mTorย signaling activation in a rat model of type 2 diabetes mellitus withย insulinย โ€ฆ
  111. The mechanism ofย insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTor) complex 1 and its contribution toย mTorย complex 1 โ€ฆ
  112. โ€ฆ a low-protein diet in utero demonstrate changes inย mTorย signaling in pancreatic islets of langerhans, associated with altered glucagon andย insulinย expression and a โ€ฆ
  113. insulin-induced stimulation of JNK and the PI 3-kinase/mTorย pathway leads to phosphorylation of serine 318 of IRS-1 in C2C12 myotubes
  114. insulinโ€like growth factorโ€1 (IGFโ€1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTor) pathway
  115. Galangin and pinocembrin from propolis ameliorateย insulinย resistance in HepG2 cells via regulating Akt/mTorย signaling
  116. insulinย Potentiates Ca2+ Signaling and Phosphatidylinositol 4,5-Bisphosphate Hydrolysis Induced by Gq Protein-Coupled Receptor Agonists through anย mTorย โ€ฆ
  117. Hexanoic, octanoic and decanoic acids promote basal andย insulin-induced phosphorylation of the Akt-mTorย axis and a balanced lipid metabolism in the HepG2 โ€ฆ
  118. โ€ฆ lychee fruit extract alleviates dietโ€inducedย insulinย resistance via suppressingย mTor/SREBPโ€1 mediated lipogenesis in liver and restoringย insulinย signaling in skeletal โ€ฆ
  119. insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3ฮฒ and PI3K/Akt/mTor-dependent โ€ฆ
  120. Amino acid-andย insulin-induced activation ofย mTorC1 in neonatal piglet skeletal muscle involves Sestrin2-GATOR2, Rag A/C-mTor, and RHEB-mTorย complex โ€ฆ
  121. The dual targeting ofย insulinย andย insulin-like growth factor 1 receptor enhances theย mTorย inhibitor-mediated antitumor efficacy in hepatocellular carcinoma
  122. insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTor/ATF4 axis
  123. Tissue-specific responses of IGF-1/insulinย andย mTorย signaling in calorie restricted rats
  124. Improvedย insulinย sensitivity by rapamycin is associated with reduction ofย mTorย and S6K1 activities in L6 myotubes
  125. Scutellarin, a modulator ofย mTor, attenuates hepaticย insulinย resistance by regulating hepatocyte lipid metabolism via SREBPโ€1c suppression
  126. Rumen-Protected Glucose Stimulates theย insulin-Like Growth Factor System andย mTor/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows
  127. Knockdown ofย insulinย receptor substrate 1 reduces proliferation and downregulates Akt/mTorย and MAPK pathways in K562 cells
  128. Intranasalย insulinย increases synaptic protein expression and prevents anesthesia-induced cognitive deficits throughย mTor-eEF2 pathway
  129. insulinย increases sestrin 2 content by reducing Its degradation through the PI3K/mTorย signaling pathway
  130. โ€ฆ acid stimulates energy metabolism and inhibitsย insulin/PI3K/AKT signaling in differentiated human neuroblastoma cells: The role ofย mTorย activation and mitochondrial โ€ฆ
  131. Rosemary Extract Activates AMPK, Inhibitsย mTorย and Attenuates the High Glucose and Highย insulin-Induced Muscle Cellย insulinย Resistance
  132. โ€ฆ Protein Kinase IV (CaMKIV) limits ER stress and improvesย insulinย sensitivity through inhibition of autophagy via theย mTor/CREB signaling pathway
  133. Adipocyte-specific DKO of Lkb1 andย mTorย protects mice against HFD-induced obesity, but results inย insulinย resistance
  134. Impaired overload-induced hypertrophy is associated with diminishedย mTorย signaling inย insulin-resistant skeletal muscle of the obese Zucker rat
  135. The inhibition ofย insulin-stimulated proliferation of vascular smooth muscle cells by rosiglitazone is mediated by the Akt-mTor-P70S6K pathway
  136. โ€ฆ the SAIN (Shc and IRS-1 NPXY binding) domain ofย insulinย receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 byย mTor
  137. insulinย increases cholesterol uptake, lipid droplet content, and apolipoprotein B secretion in CaCoโ€2 cells by upregulating SRโ€BI via a PI3K, AKT, andย mTorย โ€ฆ
  138. mTorย partly mediatesย insulinย resistance by phosphorylation ofย insulinย receptor substrate-1 on serine307 residues after burn
  139. mTorย inhibition: reducedย insulinย secretion and sensitivity in a rat model of metabolic syndrome
  140. insulin-like growth factor I suppresses bone morphogenetic protein signaling in prostate cancer cells by activatingย mTorย signaling
  141. Effect of electrical stimulation combined with diet therapy onย insulinย resistance viaย mTorย signaling
  142. insulin-stimulatedย mTorย activation in peripheral blood mononuclear cells associated with early treatment response to lithium augmentation in rodent model of โ€ฆ
  143. โ€ฆ of Free Fatty Acid (FFA)-Induced Skeletal Muscle Cellย insulinย Resistance by Resveratrol is Linked to Activation of AMPK and Inhibition ofย mTorย and p70 S6K
  144. 4-PBA reverses autophagic dysfunction and improvesย insulinย sensitivity in adipose tissue of obese mice via Akt/mTorย signaling
  145. PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing theย insulinย receptor/Akt andย mTorย signaling pathways
  146. โ€ฆ , methionine, threonine, and other amino acids onย insulinย and glucagon concentrations, mammalian target of rapamycin (mTor) signaling, and lactational โ€ฆ
  147. Anti-inflammatory action ofย insulinย via induction of Gadd45-ฮฒ transcription by theย mTorย signaling pathway
  148. Effects of dietary oxidized tyrosine products onย insulinย secretion via the thyroid hormone T3-regulated TRฮฒ1โ€“Aktโ€“mTorย pathway in the pancreas
  149. insulinย inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTorย signaling cascade but does not involve internal ribosomal entry site โ€ฆ
  150. Exercise improves skeletal muscleย insulinย resistance without reduced basalย mTor/S6K1 signaling in rats fed a high-fat diet
  151. Essential amino acids improveย insulinย activation of AKT/mTorย signaling in soleus muscle of aged rats
  152. Reduction ofย insulinย signalling pathway IRSโ€1/IRSโ€2/AKT/mTorย and decrease of epithelial cell proliferation in the prostate of glucocorticoidโ€treated rats
  153. Regulation of skeletal muscleย insulin-stimulated signaling through the MEK-REDD1-mTorย axis
  154. Attenuation ofย insulinย resistance in rats by agmatine: role of SREBP-1c,ย mTorย and GLUT-2
  155. insulin-Like Growth Factor Binding Protein-Related Protein 1 Activates Primary Hepatic Stellate Cells via Autophagy Regulated by the PI3K/Akt/mTorย โ€ฆ
  156. Medium-chain triacylglycerol suppresses the decrease of plasma albumin level through theย insulin-Akt-mTorย pathway in the livers of malnourished rats
  157. Amino acid-sensingย mTorย signaling is involved in modulation of lipolysis by chronicย insulinย treatment in adipocytes
  158. insulinย stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTorย pathway
  159. Melanocortin-4 receptor activation promotesย insulin-stimulatedย mTorย signaling
  160. insulinย activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation ofย mTor/S6K1
  161. โ€ฆ and autophagy of articular chondrocytes via modulating the phosphoinositide 3โ€kinase/protein kinase Bโ€mTorย pathway by targetingย insulinโ€like growth factorโ€1
  162. Crosstalk withย insulinย and dependence on PI3K/Akt/mTorย rather than MAPK pathways in upregulation of basal growth following long-term oestrogen โ€ฆ
  163. Effects of resveratrol, lovastatin and theย mTor-inhibitor RAD-001 onย insulin-induced genomic damage in vitro
  164. Eicosapentaenoic acid abolishes inhibition ofย insulin-inducedย mTorย phosphorylation by LPS via PTP1B downregulation in skeletal muscle
  165. insulinย regulation of hepaticย insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTor) signalling is impaired โ€ฆ
  166. The effects of amino acids on glucose metabolism of isolated rat skeletal muscle are independent ofย insulinย and theย mTor/S6K pathway
  167. Combination of the mammalian target of rapamycin (mTor) inhibitor everolimus (E) with theย insulinย like growth factor-1-receptor (IGF-1-R) inhibitor NVP-AEW-541: A โ€ฆ
  168. miR-155-5p alleviates ethanol-induced myocardialย insulinย resistance in H9C2 cells via regulating theย mTorย signalling pathway
  169. Transcription factor-7โ€“like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to controlย mTorย signaling, ฮฒ cell growth, andย insulinย secretion
  170. Preoperative oral carbohydrate improved postoperativeย insulinย resistance in Rats through the PI3K/AKT/mTorย pathway
  171. insulin-inducedย mTorย activity exhibits anti-hepatitis C virus activity
  172. In human endothelial cells amino acids inhibitย insulin-induced Akt and ERK1/2 phosphorylation by anย mTor-dependent mechanism
  173. miRโ€483 is d ownregulated in preโ€eclampsia via targetingย insulinโ€like growth factor 1 (IGF1) and regulates the PI3K/Akt/mTorย pathway of endothelial progenitor cells
  174. 1, 25 (OH) 2D3 protects trophoblasts againstย insulinย resistance and inflammation via suppressingย mTorย signaling
  175. Inhibition of PI-3 kinase/Akt/mTor, but not calcineurin signaling, reversesย insulin-like growth factor I-induced protection against glucose toxicity in โ€ฆ
  176. insulin-like growth factor binding protein-3 mediates interleukin-24-induced apoptosis through inhibition of theย mTorย pathway in prostate cancer
  177. Effect of AMPK/mTor/S6K1 pathways and theย insulin-sensitizing effect for adiponectin in endometrial cancer cells
  178. Modeling the effects ofย insulinย and amino acids on the phosphorylation ofย mTor, Akt, and 4EBP1 in mammary cells
  179. Correction:ย insulinย andย mTorย pathway regulate HDAC3-mediated deacetylation and activation of PGK1
  180. Bromodomain-containing protein 2 inducesย insulinย resistance via theย mTor/Akt signaling pathway and an inflammatory response in adipose tissue
  181. Involvement ofย mTorย in type 2 CRF receptor inhibition ofย insulinย signaling in muscle cells
  182. โ€ฆ pathway leads to phosphorylation of IRS-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mTorย insulinย biosynthetic pathway in RIN โ€ฆ
  183. Anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody cixutumumab (cix) plusย mTorย inhibitor temsirolimus (tem) in metastatic castration-resistant โ€ฆ
  184. Heparin-binding EGF-like growth factor (HB-EGF) mediates 5-HT-inducedย insulinย resistance through activation of EGF receptor-ERK1/2-mTorย pathway
  185. Branched-Chain ฮฑ-Ketoacids Regulateย insulinย andย mTorย Signalling in Skeletal and Cardiac Muscle
  186. 2313-PUB: Alterations in Basal State ofย insulinย andย mTor-Dependent Signalings Closely Related to Impaired Incretin Profile and Type 2 Diabetes in Subcutaneous โ€ฆ
  187. SDC3 acts as a timekeeper of myogenic differentiation by regulating theย insulin/AKT/mTorย axis in muscle stem cell progeny
  188. insulinย promotes the expression of the gluconeogenic rate-limiting enzymes phosphoenolpyruvate carboxykinase (Pepck) and glucose 6-phosphatase โ€ฆ
  189. Forskolin attenuates the action ofย insulinย on the Aktโ€“mTorย pathway in human skeletal muscle
  190. Anti-insulin-like growth factor-1 receptor (IGF-IR) monoclonal antibody cixutumumab plus mammalian target of rapamycin (mTor) inhibitor temsirolimus in metastatic โ€ฆ
  191. The relationship betweenย mTor/S6K1 signaling pathway andย insulinย resistance and the study of aerobic exercise on this pathway
  192. Bifurcation analysis ofย insulinย regulatedย mTorย signalling pathway in cancer cells
  193. Effects ofย insulinย on Milk Fat Synthesis by Regulating the Expressions of SREBP1 andย mTorย in Bovine Mammary Epithelial Cells.
  194. โ€ฆ Holstein male calves accelerated by branched-chain volatile fatty acids addition with up-regulated hepaticย mTorย expression viaย insulinย andย insulin-like growth factor โ€ฆ
  195. โ€ฆ Acid-andย insulin-Induced Activation of Mechanistic Target of Rapamycin Complex 1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTorย โ€ฆ
  196. insulinย Stimulation of Protein Synthesis andย mTorย Signaling in Chick Myotube Cultures
  197. Effects of dietary oxidized tyrosine products onย insulinย secretion via the thyroid hormone T3-regulated TRb1โ€“Aktโ€“mTorย pathway in the pancreas
  198. Comment on Smith et al. Protein ingestion induces muscleย insulinย resistance independent of leucine-mediatedย mTorย activation. Diabetes 2015; 64: 1555 โ€ฆ
  199. insulinย Confers Neuroprotection Against Hyperglycemic Stress-Induced Apoptosis Through PI3K/Akt/mTor/Nrf2/GCL/Redox Signaling.
  200. Molecular mechanism ofย insulinย resistance: role ofย mTorย signaling pathways
  201. Activation of the PI3K/Akt/mTorย Pathway byย insulinย Is Crucial for Amplification of FSH-Induced Differentiation, but Not Proliferation, of Ovarian Granulosa Cells.
  202. Analysis of Integratedย insulinโ€“mTorย Signalling Network-Diabetes Perspective
  203. The ageing process:ย insulinย signalling andย mTorย signalling
  204. Fish Oil and Cardiac Akt/mTor-Mediatedย insulinย Resistance in Infants with Maternal Diabetes
  205. โ€ฆ carbohydrate and branched-chain amino acids on markers of skeletal muscle protein synthesis of theย insulin-PI3K-mTorย signal transduction pathways in โ€ฆ
  206. Effects of ฮฑ-ketoglutarate on Plasma Concentrations ofย insulinย and Amino Acids andย mTorย Signal Transduction in Gastrocnemius of Piglets Challenged by โ€ฆ
  207. The Effect ofย insulin-like Growth Factor 1 (IGF-1) and Exercise on the Protein Expression of Mammalian Target of Rapamycin (mTor) and Androgen Receptor (AR) in โ€ฆ
  208. Agpat1 Decreasesย insulinย Signaling by Activating theย mTorย Pathway.
  209. Theย insulin/IGF-1, the sirtuin and theย mTorย pathway. How alterations of these pathways could affect age-related diseases and lifespan.
  210. โ€ฆ giant cell tumor with benign histologic features, treated with SCH 717โ€“454, anย insulinย growth factor receptor inhibitor, in combination with everolimus, anย mTorย โ€ฆ
  211. insulinย Stimulatesย mTorย Phosphorylation via Protein Klnase B
  212. Evaluation of combinedย insulin-like growth factor type 1 (IGF1R) andย mTorย pathway blockade in sarcoma xenograft models
  213. Effect of combined treatment withย insulin, metformin, and gliclazide on the expression and activity of Akt,ย mTor, and p70S6K protein kinases in lymphocytes of โ€ฆ
  214. Calcium/calmodulin-dependent Protein Kinase IV Limits ER stress andย insulinย Resistance through Inhibition of Autophagy in Adipocytes byย mTor/CREB Signaling
  215. Research progress of inhibitors inย mTorย andย insulin/IGF-1 signaling pathway and age-related diseases
  216. Retraction:ย insulin-Like Growth Factor I Suppresses Bone Morphogenetic Protein Signaling in Prostate Cancer Cells by Activatingย mTorย Signaling
  217. mTorย kinase activity is required by the myocardium for basal level andย insulinโ€inducedย mTorโ€mediated signals
  218. Actions ofย insulinย As a Survival and Growth Factor: Akt,ย mTor, and Regulation of Translation
  219. Hypothalamicย mTorย pathway mediates neuronal actions ofย insulin
  220. โ€ฆ -Protein Diet in Utero Demonstrate Changes inย mTorย Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon andย insulinย Expression and a โ€ฆ
  221. A high fat diet inducesย insulinย resistance andย insulin-independent activation of theย mTor-S6 kinase pathway in mouse liver
  222. Insights intoย insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt,ย mTorย signaling in regulating miR132/212 and miR 122 โ€ฆ
  223. The effect ofย mTor/S6K1 signaling pathway on the development of high fat diet-induced mouseย insulinย resistance
  224. insulin-mediated regulation of the miR132/212 cluster and miR 122/181a expression through PI3K, Akt,ย mTorย signaling in primary cultured rat hepatocytes.
  225. A Dual PI3K-mTorย Inhibitor Induced Hyperglycemia and Increasedย insulinย Signals in the Heart
  226. mTorย Signaling Pathway Regulatesย insulin-Induced Redistribution and Degradation of IRS-1 in 3T3-L1 Adipocytes
  227. Targeting theย insulin-like growth factor 1 (IGF1R) andย insulinย (IR) receptor with a dual IGF1R/IR inhibitor, OSI-906, to potentiateย mTorย inhibitor effects in experimental โ€ฆ
  228. insulin-Mediated Down-Regulation of the Anti-Angiogenic Protein PEDF isย mTorย Dependent.
  229. Hepatic Overexpression of Dominant Negative Form ofย mTorย Enhances Akt Phosphorylation and Restoresย insulinย Resistance in K/KAy Mice.
  230. The regulation of skeletal muscleย insulinโ€stimulated signaling by the MEKโ€REDD1โ€mTorย axis
  231. Abstract A56: A dual PI3K-mTorย inhibitor induced cardiac hypertrophy in mice: Role of theย insulinย signaling
  232. The role of PRAS40 inย insulinย action: at the intersection of protein kinase B (PKB/Akt) and mamalian target of rapamyein (mTor)
  233. Human postprandial blood concentrations of leucine andย insulinย increase phosphorylation ofย mTorย in C2C12 myoblasts
  234. insulinย stimulates muscle protein synthesis in neonates during endotoxemia despite suppression ofย insulin-stimulatedย mTor-dependent translation initiation
  235. Role of PRAS40 in mammalian target of rapamycin (mTor) modulation in cancer andย insulinย resistance
  236. PI3K-mTorย Axis is a Critical Node for Hypothalamicย insulinย Receptor Signaling and Sympathetic Activation Induced byย insulin
  237. insulinย Resistance Suppresses Cardiac Autophagy Through the AMPK/mTorย Pathway in Type 2 Diabetes
  238. Towards a mechanistic explanation ofย insulinย resistance, which incorporatesย mTor, autophagy, and mitochondrial dysfunction
  239. A study on the relationship ofย mTor/S6K1 signaling pathway and aerobic exercises attenuatingย insulinย resistance induced by high fat diet in mice
  240. โ€ฆ of heavy resistance exercise in combination with orally administered branched-chain amino acids or leucine onย insulinย signaling and Akt/mTorย pathway activity in โ€ฆ
  241. # 11ย insulin-like growth factor-I promotes myogenesis via bothย mTor-dependent and-independent pathways
  242. โ€ฆ derived from hR1, a humanized anti-insulin-like growth factor receptor-I monoclonal antibody, are enhanced in renal cell carcinoma and synergistic with anย mTorย โ€ฆ
  243. Supplemental Data Inappropriate Activation of the TSC/Rheb/mTor/S6K Cassette Induces IRS1/2 Depletion,ย insulinย Resistance, and Cell Survival Deficiencies
  244. Activity ofย insulinย growth factor-receptor (IGF-1R) antibody cixutumumab combined with theย mTorย inhibitor temsirolimus in patients with metastatic refractory โ€ฆ
  245. Abstract P5-11-06: Combination ofย insulin-like growth factor 1 receptor and PI3K/mTorย inhibition in triple-negative breast cancers
  246. PO-063 Exercise alleviatesย insulinย resistance by regulating MG53 and IR/IRS/AKT/mTorย signaling in db/db mice skeletal muscle
  247. โ€ฆ Michael McDaniel, Ph. D., professor of pathology and immunology, wants to use this ability to makes cells divide and maintain enoughย insulin-making beta cells โ€ฆ
  248. insulin-like Growth Factor-I Suppresses Bone Morphogenetic Protein Signaling through a Phosphatidylinositol 3-Kinase, Akt andย mTor-Dependant Mechanism
  249. insulin-Like Growth Factor Binding Protein (IGFBP) 3 Suppresses HIF1a Expression in Cancer Cells through Reactivatingย mTor/Tln Pathway
  250. Fasting and refeeding regulate in different manner SNAT 2, SREBPโ€1 and 2,ย mTor, serumย insulinย in animals fed different types of protein
  251. โ€ฆ tyrosine kinase inhibitor for focal adhesion kinase andย insulin-like growth factor-I receptor (TAE226) leads to apoptosis in esophageal cancer by inhibiting AKT-mTorย โ€ฆ
  252. Abstract LB-124:ย insulinย growth factor-receptor (IGF-1R) antibody cixutumumab combined with theย mTorย inhibitor temsirolimus in patients with refractory Ewingโ€™s โ€ฆ
  253. EFFECTS OF DISRUPTINGย insulin-LIKE GROWTH FACTOR-1 RECEPTOR (IGF-1R) SIGNAL TRANSDUCTION PATHWAYS WITH INHIBITORS OF IGF-1R โ€ฆ
  254. Impact of obesity on MMTV-Wnt-1 mammary cancer: role of theย insulin-like growth factor-1 (IGF-1)/Akt/mTorย pathway
  255. PI 3-Kinase andย mTorย Are Required forย insulinย Induced Phosphorylation of Eukaryotic Initiation Factor 4E Binding Protein 1 (4E-BP1) in Proximal Tubular Epithelial โ€ฆ
  256. Correction: Transcription factor-7โ€“like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to controlย mTorย signaling, ฮฒ cell growth, andย insulinย secretion.
  257. Impact of Obesity on MMTV-Wnt-1 Mammary Cancer: Role of Theย insulin-Like Growth Factor-1 (IGF-1)/Akt/mTorย Pathway
  258. โ€ฆ 3900: Resveratrol suppressesย insulin-like growth factor-1 promoted colon cancer cell growth via activation of p53/AMPK/TSC-2 and suppression of IGF-1R/Akt/mTorย โ€ฆ

Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

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