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Ikk
Ikk
… -activated protein kinase kinase kinase 3 (MEKK3) is required for lysophosphatidic acid (LPA)-mediated optimal i [kappa] B kinase [beta](IKK [beta])/nuclear factor …
… -induced expression of iNOS and COX-2 in BV2 murine microglial cells: possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-κB signaling …
… -insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK …
… ) stimulates matrix mentalloproteinase-9 (MMP-9) production in cultured human chorion trophoblast cells through TNF alpha receptor 1 signalling to IKK beta, ERK1/2 …
… 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1–dependent capillary-like structure formation: role of the IKK/NF-κB pathway
… acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB
… and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-
TAK1-IKK pathway”[Biochem. Pharmacol …
… and the beautiful: A small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway
… antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/IκB/NF-κB …
… as a target to increase apoptosis in primary mediastinal B-cell lymphoma (PMBL): Results of studies with rituximab (RTX), bortezomib (BTZ) and small molecule IKK …
… attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways
… between apoptosis in primary mediastinal B-cell lymphoma (PMBL) and NF-\# 954; B Pathway Blockade: Bortezomib (BTZ), small molecule IKK inhibitor ML120B and …
… cascade leading to apoptosis.) The anti-inflammatory phenolic curcumin from Curcuma species (turmeric)(Zingiberaceae) inhibits the IB kinase (IKK) and thus inhibits …
… Conditioning and Ventilation held in Hanover for the first time: Air conditioning systems made in the Far East challenge traditional systems; IKK 2001-22. Internationale …
… deacetylase inhibitors SAHA and NVP-LAQ824 is enhanced by interrupting NF-kappaB activation through a mechanism involving inhibition of IKK-mediated RelA/p65 …
… disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced …
… from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and …
… growth factor-2 15-LOX, 15-lipoxygenase receptor tyrosine kinase LPS, lipopolysaccharide iGlu-R, inhibitory glutamate receptor LT, leukotriene IKK, inhibitor B kinase …
… Impaired migration and proliferation of bone marrow-derived mesenchymal stem cells from patients with systemic lupus erythematosus were mediated by IKK-β
… in this paper: ApoE, apolipoprotein E; BAE, bovine aortic endothelial; Coll, collagen; FG, fibrinogen; FN, fibronectin; IHC, immunohistochemistry; IKK, IκB kinase; LN …
… Increases in Apoptosis in Primary Mediastinal B-Cell Lymphoma (PMBL) and NF-κB Pathway Blockade: Bortezomib (BTZ), Small Molecule IKK Inhibitor ML120B and …
… inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-
TAK1-IKK …
… low-density lipoprotein-induced inflammation in human mesangial cells through upregulation of XBP1 and suppression of the IRE1α/IKK/NF‑κB pathway
… mortality and district characteristics (IKK) of the TUeV Rheinland; Das Informationssystem ueber Krebsmortalitaet und Kreischarakteristika (IKK) des TUeV Rheinland
… of Ethanolic Extract of Pericarps of Mangosteen (Garcinia mangostana Linn.) on WiDr Cells and Interaction Study of Alpha-mangosteen to IKK and VEGF Based on …
… of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways
… of the NF-κ B pathway by the leukemogenic TEL-Jak2 and TEL-Abl fusion proteins leads to the accumulation of antiapoptotic IAP proteins and involves IKK α
… oxide level in tomato regulated by a mammalian IKK/NF-κB like signaling pathway? Is nitric oxide level in tomato regulated by a mammalian IKK/NFκB-like signaling …
… Pathways Regulating Hepatic Apolipoprotein B100 Production: Roles of Mitogen-activated Protein Kinases (MAPKs) and Inhibitor of NFkappaB Kinase (IKK) …
… pylori Induction in Gastric Mucosal Prostaglandin and Nitric Oxide Generation Is Dependent on MAPK/ERK-Mediated Activation of IKK-β and cPLA2 …
… the DKV planner’s forum at the IKK 2000; Integration lufttechnischer Systemloesungen in die Gebaeudeautomation. Beitrag vom DKV-Planerforum waehrend der IKK …
… the solution structure of IκB kinase (IKK) subunit γ and its interaction with kaposi sarcoma-associated herpes virus flice-interacting protein and IKK subunit β by EPR …
129. OVARIAN PHENOTYPE OF THE IKK CONDITIONAL KNOCKOUT MOUSE
147: Inhibitory kappa B kinase (IKK) inhibition attenuates infarct size in a murine model of myocardial ischemia-reperfusion
15‐Deoxy‐Δ12,14‐prostaglandin J2 inhibits IL‐1β‐induced IKK enzymatic activity and IκBα degradation in rat chondrocytes through a PPARγ‐independent pathway
20-HETE Activates Endothelial ACE via an IKK/NF-kB Dependent Pathway
20-SOLA, a Novel Water Soluble 20-HETE Antagonist, Reduces Blood Pressure Through Regulation of Vascular ACE Expression via an IKK Dependent Pathway
241 Tnf-α Induction of Infant Murine Brain Inflammation Via IKK/Nf Kappa B Signalling: A Potential Model for Paediatric Neuroinflammation
3, 5-Disubstituted-indole-7-
carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β
3D‐QSAR Studies on a Class of IKK‐2 Inhibitors with GALAHAD Used to Develop Molecular Alignment Models
3D‐QSAR Study of Pyridine Derivates as IKK‐2 Inhibitors
4-Hydroxyestradiol induces neoplastic transformation of human breast epithelial cells by activating IKK-NF-κB signaling: possible involvement of reactive oxygen …
5-(1H-Benzimidazol-1-yl)-3-
alkoxy-2-
thiophenecarbonitriles as potent, selective, inhibitors of IKK-ε kinase
57: Pivotal role of the IKK-related kinase IKK epsilon to modulate IL29 or type I IFN induction during hepatitis C virus infection
A dominant function of IKK/NF-κB signaling in global lipopolysaccharide-induced gene expression
A feedforward loop of NLRC5 (de) ubiquitination keeps IKK–NF-κB in check
A key mediator, PTX3, of IKK/IκB/NF-κB exacerbates human umbilical vein endothelial cell injury and dysfunction
A Kinase Upstream of IKK
A negative feedback loop between miR‐200b and the nuclear factor‐κB pathway via IKBKB/IKK‐β in breast cancer cells
A new role for IKK-α in hepatitis C virus-induced lipogenesis.
A Novel IKK Inhibitor IMD-0560: Suppresses Chronic Remodeling after Myocardial Ischemia
A Novel IKK Inhibitor Prevents Progression of Neointimal Formation After Arterial Injury in Mice
A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice
A novel IKK inhibitor suppresses heart failure and chronic remodeling after myocardial ischemia via MMP alteration
A novel role for IκB kinase (IKK) α and IKKβ in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae
A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma …
A novel, highly selective, tight binding IκB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-κB …
A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation
A recurrent deletion in the ubiquitously expressed NEMO (IKK-γ) gene accounts for the vast majority of incontinentia pigmenti mutations
A selective IKK-2 inhibitor blocks NF-κB-dependent gene expression in interleukin-1β-stimulated synovial fibroblasts
A selective novel low‐molecular‐weight inhibitor of IκB kinase‐β (IKK‐β) prevents pulmonary inflammation and shows broad anti‐inflammatory activity
A Specific IKK Inhibitor Suppresses Experimental Autoimmune Myocarditis in Rats
A TNF &alphaA-responsive kinase activity may play a key role in IKK activation.
A Truncated Form of IKKa Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer
A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer
A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer
A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFα and IL-1β
A20-binding inhibitor of nuclear factor-B (NF-B)-2 (ABIN-2) is an activator of inhibitor of NF-B (IB) kinase (IKK)-mediated NF-B transcriptional activity
AB0601 Anti-arthritis effects of (E)-2, 4-bis (P-hydroxyphenyl)-2-butenal through inhibition of IKK-beta activity
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
Abstract A41: The ASK1/IKK signaling axis mediates crosstalk between inflammation and apoptosis
Abstract B59: IKK-mediated phosphorylation of the androgen receptor: A mechanism to modulate AR-cofactor interaction
Abstract B71: Chemosensitization to bleomycin conferred by a constitutive activation of IKK pathway in viral FLIP expressing cells
Abstract LB-144: I-kappa-B kinase (IKK) ε expression in pancreatic ductal adenocarcinoma
Abstract LB-206: A novel scaffold that targets the IKK complex
Abstract P1-01-11: Nuclear immunohistochemical IKK-εexpression in flat epithelial atypia (FEA) of the breast: A predictor of ipsilateral ADH, in-situ or invasive …
Abstract P5-05-10: EIA-Induced PP2A Expression Prevents β-Trcp Mediated FOXO3a Degradation and Enhances Chemosensitization by Inhibiting TAK1/IKK …
Abstract# 1196: Pro-inflammatory cytokine RANKL promotes tumor metastasis through the RANK-IKK\# 945; pathway
Abstract# 1486: E1A-induced PP2A expression prevents\# 946; TrCP-mediated FOXO3a degradation and enhances chemosensitization by inhibiting TAK1/IKK …
Abstract# 1790: Different roles of IKK alpha and IKK beta on NF-kB pathway in mantle cell lymphoma and diffuse large B-cell ympoma
Abstract# 441: TRAF2 phosphorylation at Ser-55 inhibits stress-induced cell death by promoting prolonged IKK activation
Abstract# 4700: p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IKK inhibitor BMS-345541
Abstract# 4958: Pro-inflammatory cytokine RANKL promotes tumor metastasis through the RANK-IKK\# 945; pathway
Abstract# 5050: 4-Hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells through ROS-mediated activation of IKK
Abstract# 5269: TRAF2 suppresses IKK activity and inhibits TNFa-induced cell death independent of NF-kB activation
Abstract# 5271: PKC-iota associates and phosphorylates IKK-\# 945;/\# 946; in breast cancer cell
Abstract# 5488: IKK inhibitor Bay 11-7082 induces necrotic cell death in pre-B ALL cells
Abstract# 5672: The role of IKK\# 946;/TSC1 regulation in tumorigenesis and insulin resistance
Accumulation of phosphorylated IκBα and activated IKK in nodes of Ranvier
Acetylation of MEK2 and IκB kinase (IKK) activation loop residues by YopJ inhibits signaling
Activation mechanisms of endothelial NF-κB, IKK, and MAP kinase by tert-butyl hydroperoxide
Activation of a Subset of Genes by IFN-γ Requires IKKβ but Not Interferon-Dependent Activation of NF-κB
Activation of G-protein-coupled estrogen receptor inhibits the migration of human nonsmall cell lung cancer cells via IKK-β/NF-κB signals
Activation of IKK by thymosin α1 requires the TRAF6 signalling pathway
Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice
Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells
Activation of PI3K/Akt/IKK-α/NF-κB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Activation of the IκBα kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase …
Activation of the virus-induced IKK/NF-kB signaling axis is critical for the replication of HCMV in quiescent cells
Activation of the virus‐induced IKK/NF‐κB signalling axis is critical for the replication of human cytomegalovirus in quiescent cells
Active nuclear IKK correlates with metastatic risk in cutaneous squamous cell carcinoma
Activity of bortezomib, a proteasome inhibitor, in breast cancer cells: Association with negative estrogen receptor and IKK/NF-κB expression
Adenovirus mediated gene transfer of mutated IKK and IκBα reveal NF-κB dependent as well as independent pathway of HAS1 activation
Adenovirus-mediated IKK β KA expression sensitizes prostate carcinoma cells to TRAIL-induced apoptosis
Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-κB/PTEN …
Advances in targeting IKK and IKK-related kinases for cancer therapy
Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK
Akt/IKK [alpha]/Vav1 Signaling in Endothelial Cell Survival and Angiogenesis
Alpha-lipoic acid inhibits TNF-α induced NF-κB activation through blocking of MEKK1–MKK4–IKK signaling cascades
Altered TAB1: IKK Interaction Promotes TGF-β-Mediated NF-κB Activation During Breast Cancer Progression
Amelioration of Arthritis by Intraarticular Dominant Negative IKKβ Gene Therapy Using Adeno-Associated Virus Type 5
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure–activity relationship
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
Angiogenin mediates immune modulation and antiinflammatory reaction attenuating protein kinase IKK-ε in human corneal fibroblast cells
Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis
Anthrax lethal toxin enhances I kappa B kinase (IKK) activation and differentially regulates pro-inflammatory genes in human endothelium (135.3)
Anti-inflammatory effects of IKK inhibitor XII, thymulin, and fat-soluble antioxidants in LPS-treated mice
Anticancer agent CHS 828 suppresses nuclear factor‐κB activity in cancer cells through downregulation of IKK activity
Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells
Apigenin suppresses IKK activation and downstream signaling leading to prostate cancer inhibition.
Apoptotic role of IKK in T-ALL therapeutic response
Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
Aspirin inhibits IKK-β-mediated prostate cancer cell invasion by targeting matrix metalloproteinase-9 and urokinase-type plasminogen activator
Association of a Network of Interferon-Stimulated Genes with a Locus Encoding a Negative Regulator of Non-conventional IKK Kinases and IFNB1
Association of the adaptor TANK with the IκB kinase (IKK) regulator NEMO connects IKK complexes with IKKε and TBK1 kinases
Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK …
ATM is required for IκB kinase (IKK) activation in response to DNA double strand breaks
ATM-and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
ATM-dependent nuclear accumulation of IKK-α plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin
ATP alters IKK-2 inhibitor affinity for IKK2 enzyme and reveals non-equivalent inhibitor binding sites
ATS Abstract: IKK-ß Is Required For Rhinovirus Induced IFN-ß, IFN-» And Pro-inflammatory Cytokine Production In Vitro And In Vivo
Atypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-γ)
Aurora and IKK kinases cooperatively interact to protect multiple myeloma cells from Apo2L/TRAIL
Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway
BAG3 is required for IKK α nuclear translocation and emergence of castration resistant prostate cancer
Bcl3 phosphorylation by Akt, Erk2, and IKK is required for its transcriptional activity
Benznidazole blocks NF-κB activation but not AP-1 through inhibition of IKK
Benzoxathiolone LYR-64 inhibits NF-kB activation via IKK complexin LPS-stimuated macrophages RAW 264. 7
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-κB, u-PA and MMP-2 and …
Betafectin immunomodulator increases the activities of JNK and IKK kinases and increases the nuclear translocation of AP-1 in macrophage cells.
BIOCHEMICAL CHARACTERIZATION OF SUPPRESSOR OF IKK-ε AND NAK-ASSOCIATED PROTEIN 1
Biochemical Properties of IKK and Bcl3
Bioinformatics Predictions of IKK Related Proteins Binding Long Non-Coding RNAs
Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications
Biomechanical signals inhibit IKK activity to attenuate NF‐κB transcription activity in inflamed chondrocytes
Bortezomib Increases IL-8 Expression in Ovarian Cancer Cells Through IKK and EGR-1 Pathways
Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components
Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1
C-Terminal Serine Rich Region of IKK– Interacts with Bfl-1, a Homologue of Bcl-2
C70 THE NEXT NEW THERAPEUTIC TARGET? TRANSLATIONAL STUDIES OF COPD THERAPIES: The Effect Of An Ikgr; b-Kinase-[Beta](IKK [Beta]) Inhibitor On …
Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-κB activity in LPS-stimulated mouse peritoneal …
Caffeic acid regulates LPS-induced NF-κB activation through NIK/IKK and c-Src/ERK signaling pathways in endothelial cells
Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure
Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts
CFC replacement in the focus of attention at the IKK’91 in Essen. IKK 91 in Essen im Zeichen der FCKW-Substitution
Characterization of the bovine IκB kinases (IKK) α and IKKβ, the regulatory subunit NEMO and their substrate IκBα
Characterization of the IKK Signaling Complex
Characterization of the inhibitor of kappaB kinase (IKK) complex in granulosa cell tumors of the ovary and granulosa cell tumor-derived cell lines
Chemosensitization in non‐small cell lung cancer cells by IKK inhibitor occurs via NF‐κB and mitochondrial cytochrome c cascade
Chlamydia pneumoniae activates IKK/IκB-mediated signaling, which is inhibited by 4-HNE and following primary exposure
Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK
cIAP2 negatively regulates proliferation and tumourigenesis by repressing IKK activity and maintaining p53 function
Ciglitazone ameliorates lung inflammation by modulating the IKK/NF-κB pathway following hemorrhagic shock
CIGLITAZONE REDUCES NF-κB ACTIVITY BY INHIBITING IKK IN HEMORRHAGIC SHOCK.: 58
Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: Guggulsterone regulates …
CITED2 modulates metastatic ability through effects on IKK-alpha in breast cancer cells
Classical NF-κB activation impairs skeletal muscle oxidative phenotype by reducing IKK-α expression
Clinical study on the relationship between the activation of the IKK-IκB-NFκB pathway and insulin resistance
Cloning and characterization of an IKK homologue from pearl oyster, Pinctada fucata
Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-κB signaling pathway
Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-κB signal …
Coincident enrichment of phosphorylated IκBα, activated IKK, and phosphorylated p65 in the axon initial segment of neurons
Collagen and prostaglandin E2 regulate aromatase expression through the PI3K/AKT/IKK and the MAP kinase pathways in adipose stromal cells
Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IκB kinase-2 (IKK-2) target safety and efficacy
Complete Reconstitution of Human IκB Kinase (IKK) Complex in Yeast ASSESSMENT OF ITS STOICHIOMETRY AND THE ROLE OF IKKγ ON THE COMPLEX …
Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/p38MAPK pathways in RAW264. 7 …
Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signaling
Compressive mechanical stress may activate IKK-NF-κB through proinflammatory cytokines in MC3T3-E1 cells
Conjugated linoleic acids produced by Lactobacillus dissociates IKK-γ and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells
Connecting inflammation and cancer through the IKK-NF-κB nexus
Constitutive Activation of NF-kappaB in Prostate Carcinoma Cells Through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)
Constitutive Activation of NF-Kb in Prostate Carcinoma Cells through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)
Constitutive activation of TAK1 by HTLV-1 tax-dependent overexpression of TAB2 induces activation of JNK-ATF2 but not IKK-NF-κB
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKϵ …
Context-dependent regulation of autophagy by IKK-NF-κB signaling: Impact on the aging process
Control of canonical NF-κB activation through the NIK–IKK complex pathway
Control of osteoclast activity and bone loss by IKK subunits: new targets for therapy
Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I tax-mediated tumorigenesis
Correlation between the signal pathway IKK/NF-? B and the anti-oxidant activity in asthma rats and the modulation of Ginkgo biloba extract
Counter-regulation in the IKK family
Crosstalk between the NF‐κB activating IKK‐complex and the CSN signalosome
Crystal structure of a vFlip-IKKγ complex: insights into viral activation of the IKK signalosome
Curcumin dually inhibits both mTOR and NF-κB pathways through a crossed PI3K/Akt/IKK signaling axis in adenoid cystic carcinoma
Curcumin Treatment Suppresses IKK Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study
Cutting edge: the IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death
Cytosolic Hsp60 is involved in the NF-κB-dependent survival of cancer cells via IKK regulation
Cytotoxic Necrotizing Factor 1 Prevents Apoptosis via the AKT/IKK pathway: Role of NF-κB and Bcl-2
Daphnetin inhibits TNF‐α and VEGF‐induced angiogenesis through inhibition of the IKK s/IκBα/NF‐κB, Src/FAK/ERK 1/2 and Akt signalling pathways
Davallia bilabiata Inhibits TNF-α-Induced Adhesion Molecules and Chemokines by Suppressing IKK/NF-kappa B Pathway in Vascular Endothelial Cells
Dbl and the Rho GTPases activate NFκB by IκB kinase (IKK)-dependent and IKK-independent pathways
De-ubiquitylation is the most critical step in the ubiquitin-mediated homeostatic control of the NF-jB/IKK basal activity
De-ubiquitylation is the most critical step in the ubiquitin-mediated homeostatic control of the NF-κB/IKK basal activity
Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1
Decreased IKK Signaling in Skeletal Muscle of Patients with Hyperglycemic Crisis.
Deficient natural killer cell cytotoxicity in patients with IKK-γ/NEMO mutations
Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK
determine distinct IKK α Pleiotropic functions of TNF
Dextran-g-lauric acid as IKK complex inhibitor carrier
Differential IKK/NF-kB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells
Differential IKK/NF-κB activity is mediated by TSC2 through mTORC1 in PTEN-null prostate cancer and tuberous sclerosis complex tumor cells
Differential Requirement for the IKK
Direct Phosphorylation of I kappa B by IKK [small alpha, Greek] and IKK [small beta, Greek]: Discrimination Between Free and NF-kappa B-Bound Substrate
Direct, noncatalytic mechanism of IKK inhibition by A20
Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)
Discovery of 6-aryl-azabenzimidaoles that inhibit the TBK1/IKK-ε kinases
Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques
Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1
DISCOVERY OF NOVEL IKK-Β INHIBITOR BY STRUCTURAL MODIFICATIONS OF CHLORPROPAMIDE AND NATEGLINIDE
Discovery of novel potent nuclear factor kappa‐B inhibitors (IKK‐β) via extensive ligand‐based modeling and virtual screening
Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors
Disrupting the inhibitory Kappa B kinase (IKK)-Aurora A axis in cancer
Disruption of IκB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors
Distinct activation mechanisms of NF-κB regulator inhibitor of NF-κB kinase (IKK) by isoforms of the cell death regulator cellular FLICE-like inhibitory protein (cFLIP)
Distinct B subunits of PP 2A regulate the NF‐κB signalling pathway through dephosphorylation of IKK β, IκBα and RelA
Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance
Diversity oriented synthesis and IKK inhibition of aminobenzimidazole tethered quinazoline-2, 4-diones, thioxoquinazolin-4-ones, benzodiazepine-2, 3, 5-triones …
DMA, a Bisbenzimidazole, Offers Radioprotection by Promoting NFκB Transactivation through NIK/IKK in Human Glioma Cells
Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways
Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in Tax-mediated activation of IKK
Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis
Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
Dynamic Characterization of the IKK: κBα: NFκB Negative Feedback Loop Using Real-Time Bioluminescence Imaging
Dynamic interaction of stress granules, DDX3X, and IKK-α mediates multiple functions in hepatitis C virus infection
E1A inhibition of radiation-induced NF-κB activity through suppression of IKK activity and IκB degradation, independent of Akt activation
Effect and mechanism of IKK-2 receptor blocker on corneal stromal fibroblasts
Effect and significance of anisodamine on I-kappaB kinase (IKK) in traumatic lung injury
Effect of Collaterals-smoothing Drugs on Expressions of IκB-a and IKK-a in Sciatic Nerve of Diabetic Rats
Effect of FK506 and Cyclosporin A on IκBα Degradation and IKK Pathway in Bronchial Epithelial Cells, Monocytes, Lymphocytes and Alveolar Macrophages
Effect of IKK-2 Inhibitor on Local Th1 and Th2 Type Inflammation
Effect of IKK-beta specific inhibitor PS1145 on NF-kappaB activity and apoptosis in prostate carcinoma cell lines
Effect of Kuijieling decoction on proteins expression of IKK-alpha in colonic mucosa of ulcerative colitis model rats
Effect of Rosiglitazone on Insulin Resistance and ROS. IKK Signaling Pathway in Vascular Endothelial Cells
Effect of rosiglitazone on phosphorylation IKK and IκBα in the Heart of STZ Diabetic Rats [J]
Effective suppression of pro‐inflammatory molecules by DHCA via IKK‐NF‐κB pathway, in vitro and in vivo
Effects of a brief high-fat diet and acute exercise on the mTORC1 and IKK/NF-κB pathways in rat skeletal muscle
Effects of IKK inhibitor PS1145 on NF-κ B function, proliferation, apoptosis and invasion activity in prostate carcinoma cells
Effects of P-MAPA immunomodulator on Toll-like receptor 2, ROS, nitric oxide, MAPKp38 and IKK in PBMC and macrophages from dogs with visceral leishmaniasis
Effects of Soothing Liver and Invigorating Spleen Recipes on the IKK-NF-B Signaling Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis Rats
Effects of TCDD upon IκB and IKK subunits localized in microsomes by proteomics
El BUSINESS If IKK
Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-β-deficient mice
EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-κB andMKK7/JNK …
Endothelial cell injury and dysfunction induced by silver nanoparticles through oxidative stress via IKK/NF-κB pathways
Endothelial IKK β Signaling is Required for Monocyte Adhesion under Laminar Flow Conditions
Endothelial-specific Deletion of Inhibitor of Kappa-B Kinase-β (IKK-β)
Energy calibration of the IKK fast chopper with 238U standards
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation
Epstein–Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-κ B2 to p52 via an IKK γ/NEMO-independent signalling …
ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK
ERK is an anti-inflammatory signal that suppresses expression of NF-κB-dependent inflammatory genes by inhibiting IKK activity in endothelial cells
Erratum to” Discovery of novel and selective IKK-b serine-threonine protein kinase inhibitors. Part 1″-(Bioorg. Med. Chem. Lett. 13 (2003) 913)
Etanercept Reverses Downregulation of Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha (IKK [alpha]) in Psoriasis
Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-
TAK1-IKK pathway mediates constitutive NF-κ B activation and proliferation in human head and neck …
Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-B activation
Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-κB activation
Exploring Suppressor of IKK Epsilon’s Interaction with Cytoskeletal Proteins
Expression and function of NIK‐and IKK 2‐binding protein (NIBP) in mouse enteric nervous system
Expression and regulation of inducible IκB kinase (IKK-i) in human fibroblast-like synoviocytes
Expression, purification and functional characterization of IκB kinase-2 (IKK-2) mutants
Faculty, IKK
FAF1 suppresses IκB kinase (IKK) activation by disrupting the IKK complex assembly
Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes
Fanconi anemia protein complex is a novel target of the IKK signalsome
Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
Fentanyl Suppresses the Survival of CD4+ T Cells Isolated from Human Umbilical Cord Blood through Inhibition of IKKs‐mediated NF‐κB Activation
fibrosis) at 28-days post reperfusion, which was markedly reduced by the late administration of IKK16. Conclusion: The late inhibition of IKK may, therefore, have …
Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways
Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-β kinase pathway
FOXO 3 as a new IKK‐ε‐controlled check‐point of regulation of IFN‐β expression
FoxO transcription factor is delocalized in CML patients by Bcr-Abl induced PI3K/AKT activation and IKK pathway and can be reactivated by Imatinib treatment
FoxO Transcription Factor Is Delocalized in CML Patients by Bcr-Abl Induced PI3K/AKT Activation and IKK Pathway and Can Be Reactivated by Imatinib Treatment.
Functional analysis of astroglial IKK/NF-KappaB signaling in brain development and homeostasis
Functional Role of c-Src in IL-1–Induced NF-κB Activation: c-Src Is a Component of the IKK Complex
GD2+ breast cancer stem cell growth is dependent on NFκB signaling and suppressed by the IKK inhibitor BMS345541 in vitro and in vivo
Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis
Ghrelin Suppression of Helicobacter pylori-Induced Gastric Mucosal Expression of iNOS is Mediated through the Inhibition of IKK-β Activation by cNOS …
Gold compound auranofin inhibits IκB kinase (IKK) by modifying Cys-179 of IKKβ subunit
GPx-1 Gene Delivery Modulates NFκB Activation Following Diverse Environmental Injuries Through a Specific Subunit of the IKK Complex
GW26-e1432 Effect of Rosiglitazone on Insulin Resistance and ROS/IKK Signaling Pathway in Vascular Endothelial Cells
GW26-e2212 Effect of Atorvastatin on IKK/NF-кB Pathway of Insulin Resistance in Vascular Endothelial Cells
GW27-e0848 Effect of Celastrol on Insulin Resistance and ROS/IKK Signaling Pathway in Vascular Endothelial Cells
H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-κB signal pathway
hCINAP negatively regulates NF-κB signaling by recruiting the phosphatase PP1 to deactivate IKK complex
HDAC/IKK inhibition therapies in solid tumors.
Heat shock treatment suppresses angiotensin II-induced activation of NF-κB pathway and heart inflammation: a role for IKK depletion by heat shock?
Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated …
Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage‐mediated chronic inflammation
Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly
Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE* 3-Leiden mice
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways
High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction
Hijacking of host cell IKK signalosomes by the transforming parasite Theileria
Histone deacetylase (HDAC) inhibition induces IκB kinase (IKK)-dependent interleukin-8/CXCL8 expression in ovarian cancer cells
Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
Hit Identification of IKK-beta Natural Product Inhibitor
Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors
Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model
Honokiol inhibits TNF-α-stimulated NF-κB activation and NF-κB-regulated gene expression through suppression of IKK activation
Host and parasite-derived IKK activities direct distinct temporal phases of NF-κB activation and target gene expression following Toxoplasma gondii infection
How NF-κB is activated: the role of the IκB kinase (IKK) complex
HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination
Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)
HTLV-1 tax functions as a ubiquitin E3 ligase for direct IKK activation via synthesis of mixed-linkage polyubiquitin chains
HTLV-1 tax induces formation of the active macromolecular IKK complex by generating Lys63-and Met1-linked hybrid polyubiquitin chains
HTLV-1 Tax protein induces autophagy via IKK in human astroglioma cells: a protective mechanism against death receptor-mediated apoptosis (610.1)
HTLV-1 Tax stimulates ubiquitin E3 ligase, ring finger protein 8, to assemble lysine 63-linked polyubiquitin chains for TAK1 and IKK activation
Hyaluronan induces MMP-9 secretion through FAK-IKK/IκBα pathways and 17-AAG down-regulates these pathways in human glioma cells
Hydrogen peroxide has opposing effects on IKK activity and I κ B α breakdown in airway epithelial cells
Hyper activation of β‐catenin signalling induced by IKK ε inhibition thwarts colorectal cancer cell proliferation
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
Hypoxia activates IKK–NF-κB and the immune response in Drosophila melanogaster
I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin’s lymphoma
Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-κB and JNK/p38 MAPK pathways
Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the
Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays
Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity
Identification of mutations in TRAPPC9, which encodes the NIK-and IKK-β-binding protein, in nonsyndromic autosomal-recessive mental retardation
IDENTIFICATION OF NOVEL SUBSTRATE I-TRAF OF IKK-i KINASE
Identification of plumericin from Himatanthus Sucuuba as a novel potent inhibitor of the NF-κB pathway directly targeting IKK-β
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)
IKK Alfred, Crosby-house, 95, Bishopsgate-street
IKK alpha coordinates with RAS to switch well-differentiated papillomas to poorly differentiated malignant carcinomas in skin
IKK alpha induces angiogenesis
IKK alpha play an inhibitory role in malignant skin tumor progression
IKK and (Beta)-Catenin in Breast Cancer
IKK and Caspases in Regulating Cell Shape
IKK and Diabetic Nephropathy [J]
IKK and NF‐κB‐mediated regulation of Claspin impacts on ATR checkpoint function
IKK antagonizes activation-induced cell death of CD4+ T cells in aged mice via inhibition of JNK activation
IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-κB activity
IKK at the 580 revolutions the “down” run was made
IKK biology
IKK Capt. Gabriel J., 6, Belsize-park, Hampstead
IKK Charles Henry, 51, King’s-road, Camden-town
IKK connects autophagy to major stress pathways
IKK cuts both ways in Huntington’s disease
IKK Electric F40LW-RS-WMII at approximately 1000
IKK epsilon Deficiency Exacerbates Inflammation in the Absence of an Interferon Response in Murine Arthritis by Delaying Neutrophil Apoptosis
IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis
IKK epsilon, STAT1, and IFIT2 define a novel innate immune effector pathway against West Nile virus infection
IKK exceptional, viz. the temperature high and the air
IKK expression as an immunohistochemical marker for diagnosis of high risk flat epithelial atypia (FEA) of the breast
IKK Goes BAD
IKK have not saved, and to bury them when
IKK Henry Charles, 86, South-hill-park, Hampstead
IKK inhibition by BMS-345541 suppresses breast tumorigenesis and metastases by targeting GD2+ cancer stem cells
IKK inhibition increases bortezomib effectiveness in ovarian cancer
IKK inhibition prevents PM2. 5-exacerbated cardiac injury in mice with type 2 diabetes
IKK inhibitor PS1145 increases sensitivity of pancreatic cancer cells to TRAIL-induced apoptosis.
IKK inhibitor suppresses epithelial-mesenchymal transition and induces cell death in prostate cancer
IKK inhibitory activities of imidazo [1, 2-a] pyrazine, imidazo [1, 2-a] quinoxaline, imidazo [1, 5-a] quinoxaline and pyrazolo [1, 5-a] quinoxaline derivatives.
IKK interacts with rictor and regulates mTORC2
IKK is a therapeutic target in KRAS-induced lung cancer with disrupted p53 activity
IKK jar of the previous dayforgiven, if not for
IKK kinase assay for assessment of canonical NF-κB activation in neurons
IKK Links the Steroid Receptor Coactivator to Immune Responses
IKK low much or how little it surprised
IKK M.-What is memory aging the aging of? Developmental Psychology. 1978, 14
IKK mediates ischemia-induced neuronal death
IKK my passage-money is more than I can
IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model
IKK of ease, and little alle
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors
IKK phosphorylation of NF-κB at serine 536 contributes to acquired cisplatin resistance in head and neck squamous cell cancer
IKK Phosphorylation, ICAM–1, and CD11a/LFA–1 Increases Are Correlated With VEGF–Induced Blood–Retinal Barrier Breakdown and Are Blocked by Triamcinolone …
IKK Proverb,” that he who i
IKK regulates the deubiquitinase CYLD at the postsynaptic density
IKK regulation and human genetics
IKK results are included AAAAA
IKK SCienCe
IKK Targets PI3K
IKK that the fact was not suspected in his life
IKK the night and the morrow in that disa
IKK The North Central High School, Spökano
IKK to British subjects, residing at Zan
IKK to us, nor could it have influenced our
IKK were entitled to protection against this system of
IKK with ebonite is shown in the following
IKK with Mr. E, Jones, Hibernian Schools, Liver.
IKK yearly by government auditor, and pub
IKK α represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the …
IKK β in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5
IKK β inhibitor identification: a multi-filter driven novel scaffold
IKK β programs to turn on the GADD45α/MKK4/JNKs apoptotic cascade specifically via p50 NF-κB in arsenite response
IKK β regulates endothelial thrombomodulin in a Klf2‐dependent manner
IKK β-targeted anti-inflammatory activities of a butanol fraction of artificially cultivated Cordyceps pruinosa fruit bodies
IKK-±: An Alternative Player In Inflammation-Induced Loss Of Muscle Oxidative Phenotype In COPD?
IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation
IKK-2
IKK-2 inhibitor TPCA-1 represses nasal epithelial inflammation in vitro.
IKK-2 is required for TNF-α-induced invasion and proliferation of human mesenchymal stem cells
IKK-2/NF-κB-DEPENDENT TRANSCRIPTION
IKK-alpha PROTEIN, NUCLEIC ACID ENCODING THE SAME AND METHOD
IKK-and NF-κB-mediated functions in carcinogenesis
IKK-Beta Deletion Alleviates the Atherogenetic Effect of Intermittent Hypoxia Induced Macrophage Foam Cell Formation
IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1
IKK-dependent, NF-κB-independent control of autophagic gene expression
IKK-epsilon contributes to the malignant progression of ovarian cancer
IKK-Epsilon, a novel factor identified by proteomics, contributes to prostate cancer cell-induced osteoclast activity in vitro.
IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2 COMPARATIVE ANALYSIS OF RECOMBINANT HUMAN IKK-i, TBK-1, AND IKK-2
IKK-i signals through IRF3 and NFκB to mediate the production of inflammatory cytokines
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases
IKK-i/IKKϵ controls constitutive, cancer cell-associated NF-κB activity via regulation of Ser-536 p65/RelA phosphorylation
IKK-IKB-NF-kB gene manipulations and polymorphisms in relation to susceptibility to different diseases
IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen
IKK-mediated signaling controls prostate tumor initiating cells
IKK-NBD peptides exert anti-inflammation effect in rats after focal cerebral cortex ischemia/reperfusion via regulating c-rel [J]
IKK-related genetic diseases: probing NF-κB functions in humans and other matters
IKK-β inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches
IKK-β links inflammation to obesity-induced insulin resistance
IKK-β mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death
IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1
IKK-β Recombinant Adenovirus
IKK-β/NF-κB p65 mediates p27Kip1 protein degradation in arsenite response
IKK-γ is an essential regulatory subunit of the IκB kinase complex
IKK-γ, GST-tagged, human recombinant, expressed in Sf9 cells
IKK-ε coordinates invasion and metastasis of ovarian cancer
IKK‐β‐mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury
IKK? and synovial inflammation
IKK? is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity
IKK/NF-kappaB serving as essential components of the MAP kinase signal transduction pathway.
IKK/NF-κB activation is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils
IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance
IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut
IKK/NF-κB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors
IKK/NF-κB signaling: balancing life and death–a new approach to cancer therapy
IKK/NF-κB system protects from Hepatitis B surface antigen-induced hepatocarcinogenesis
IKK/NF-κB/Rel in Acute Pancreatitis and Pancreatic Cancer: Torments of Tantalus
IKK/NF‐κB and STAT3 pathways: central signalling hubs in inflammation‐mediated tumour promotion and metastasis
IKK/nuclear factor-kappaB and oncogenesis: roles in tumor-initiating cells and in the tumor microenvironment
IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells
IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
Improved Intraportal Islet Transplantation Outcome by Systemic IKK‐beta Inhibition: NF‐κB Activity in Pancreatic Islets Depends on Oxygen Availability
in vivo Cardiac Gene Transfer of Dominant Negative IKK-beta Reduces Myocardial Inflammation, Apoptosis, and Infarction after Ischemia-Reperfusion Injury
In Vivo Cardioprotection by Pitavastatin From Ischemic-reperfusion Injury Through Suppression of IKK/NF-κB and Upregulation of pAkt–e-NOS
In Vivoandin VitroRecruitment of an IκBα-Ubiquitin Ligase to IκBα Phosphorylated by IKK, Leading to Ubiquitination
Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation
Inactivation of Bcl‐2 through IκB kinase (IKK)‐dependent phosphorylation mediates apoptosis upon exposure to 4‐hydroxynonenal (HNE)
Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation
Induction in gastric mucosal prostaglandin and nitric oxide by Helicobacter pylori is dependent on MAPK/ERK-mediated activation of IKK-β and cPLA2: modulatory …
Induction of proinflammatory mediators requires activation of the TRAF, NIK, IKK and NF‐κB signal transduction pathway in astrocytes infected with Escherichia coli
Inflammation and the IKK β/I κ B/NF-κ B axis in obesity-and diet-induced insulin resistance
Influence of low level and long-term arsenic exposure to the phosphorylated protein kinase B as well as its downstream signal factor IKK, I-ΚB and NF-κB in HaCat …
Influence of oleanolic acid pretreatment to the IKK/I-κB/NF-κB signaling pathway during rat’s HIRI [J]
Influence of rosuvastatin calcium and telmisartan on the expressions of IKK, ROS of insulin resistance rat liver
Influenza A virus‐encoded NS 1 virulence factor protein inhibits innate immune response by targeting IKK
Information and communication platform for crisis management (IKK)
Inhibition of canonical IKK/NF-kB signaling in Hepatitis B Virus surface antigen transgenic mice drastically increases HCC development due to dysregulated Unfolded …
Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I‐κB kinase (IKK) inhibitors
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK …
Inhibition of herpesvirus-induced HIV-1 replication by cyclopentenone prostaglandins: role of IκB kinase (IKK)
Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel α-methylene-γ …
Inhibition of IKK [Beta] ReversesInsulin Resistance’in Cultured Cells
Inhibition of IKK activation, through sequestering NEMO, blocks PMMA‐induced osteoclastogenesis and calvarial inflammatory osteolysis
Inhibition of IKK activity enhances cell cycle arrest through p53-dependent p21Cip/WAF1 activation.
Inhibition of IKK down‐regulates antigen+ IgE‐induced TNF production by mast cells: a role for the IKK‐IκB‐NF‐κB pathway in IgE‐dependent mast cell activation
Inhibition of IKK-2 by 2-[(aminocarbonyl) amino]-5-acetylenyl-3-
thiophenecarboxamides
Inhibition of IKK-NFκB pathway sensitizes lung cancer cell lines to radiation
Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua)
Inhibition of IKK-β: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32
Inhibition of IKK/NF-κB impairs glioma stem cell function
Inhibition of IKK/NF-κB signaling enhances differentiation of mesenchymal stromal cells from human embryonic stem cells
Inhibition of IL-6 Release in Vitro by in Vivo Administration of an IKK Inhibitor in Mice with Lung Fibrosis Induced by Poly I: C
Inhibition of IκB kinase (IKK) protects against peripheral nerve dysfunction of experimental diabetes
Inhibition of IκB phosphorylation by a novel IKK inhibitor IMD-1041 attenuates myocardial dysfunction after infarction
Inhibition of IκB Phosphorylation by a Novel IKK Inhibitor IMD-1041 Attenuates Myocardial Dysfunction After Infarction
Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia
Inhibition of NF-κB activation by a novel IKK inhibitor reduces the severity of experimental autoimmune myocarditis via suppression of T-cell activation
Inhibition of osteoblast functions by IKK/NF-κB in osteoporosis
Inhibition of rosiglitazone on the expression of IKK-# beta# in the livers of rats with nonalcoholic steatohepatitis
Inhibition of the canonical IKK/NFκB pathway sensitizes human cancer cells to doxorubicin
Inhibition of the IKK pathway restores PI3-K activity in high-fat fed rodent skeletal muscles
Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice
Inhibition of the IKK/NF-κB pathway impairs glioma stem cell function
Inhibition of the NF-κ B survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-κ B essential modulator NEMO
Inhibition of type I interferon production via suppressing IKK-gamma expression: a new strategy for counteracting host antiviral defense by influenza A viruses?
Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1
Inhibitor-κB Kinase (IKK) β Regulates LPS-induced TNF-α Production in Cardiac Myocytes Through Modulation of NF-κB p65 Subunit Phosphorylation
Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90
Insulin exerts anti-inflammatory effects through reduction of IKK/IκB/NF-κB pathway activation in septic rats
Insulin Receptor and IRS-1 Co-immunoprecipitation with SOCS-3, and IKK?/? Phosphorylation are Increased in Obese Zucker Rat Skeletal Muscle
Insulin resistance, inflammation, and the IKK/IκB/NF-κB pathway
Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-κB signaling
Integrating cell-signalling pathways with NF-κB and IKK function
Integration of TNF-a Signaling: Crosstalk between IKK, JNK, and Caspases
Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase 2 (IKK2, IKK-beta, IKBKB) and TRAF2 indicating a dose dependent regulatory …
Interaction of vehicle and terrain results from 10 years research at IKK
Interferon Regulatory Factors and the Atypical IKK-Related Kinases TBK1 and IKK-ε: Essential Players in the Innate Immune Response to RNA Virus Infection
Interleukin-18 is a Potent Inducer of EMMPRIN Expression Both in vitro and in vivo, and Their Crosstalk Induces MMP9 Expression via PI3K-Akt-IKK-NF-κB …
Intermittent hypoxia induces murine macrophage foam cell formation by IKK-β-dependent NF-κB pathway activation
Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
Intestinal carcinogenesis: IKK can go all the way
Intestinal epithelial cells release CXCL-2 in response to lipopolysaccharide via NF-KB and IKK activation
Investigating IKK dynamics in the NF-κB signalling pathway using X-machines
Investigation on constitutive IKK activity in the axon initial segment
Involvement of cAMP-and IKK-2-Dependent Signal Pathways in the Growth Capacity of Mesenchymal Progenitor Cells under the Influence of Basic Fibroblast Growth …
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
Involvement of the ubiquitin‐like domain of TBK1/IKK‐i kinases in regulation of IFN‐inducible genes
Iron causes interactions of TAK1, p21ras and PI3K in caveolae to activate IKK in hepatic macrophages
IκB kinase (IKK) β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway
IκB kinase-2-independent and-dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic
IκB Kinases (IKK) and Diabetic Retinopathy
JNK or IKK, AP-1 or NF-κB, which are the targets for MEK kinase 1 action?
Juncture of the cytoskeleton and innate immune signaling pathways: the role of Suppressor of IKK epsilon (SIKE)
Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats
Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
Kinetic mechanisms of IκB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer
kk IKK the Flatheads. TC Elliott (Oregon Historical Quarterly
kkkk kkk tO 豎 in the IKK and protection of public health
KSHV vFLIP binds to IKK-γ to activate IKK
KSK5104, IKK-β Inhibitor for Treating Reumatoid Arthrotis
LEVELS OF IL-10 ALTER NF-KAPPA B ACTIVATION THROUGH REGULATION OF I KAPPA KINASE (IKK) IN BOTH HUMAN AND MOUSE CELL TYPES: 273
LF15‐0195 generates tolerogenic dendritic cells by suppression of NF‐κB signaling through inhibition of IKK activity
Lin28B mediated IKK-β sustains the stemness of breast cancer stem cell via regulating Wnt/TCF4 and miR-34a/LEF1 signaling pathway
Linoleic Acid Induces Expression of Monocyte Chemoattractant Protein 1 via PI3K, PKC, IKK, and NF-b Pathway in Retinal Pigment Epihelial Cells
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB
Lipopolysaccharide-mediated Interferon Regulatory Factor Activation Involves TBK1-IKK-dependent Lys 63-linked Polyubiquitination and Phosphorylation of …
Local administration of IKK small molecule inhibitor may enhance fracture healing in osteoporosis patient
Local and Systemic IKK and NF-B Signaling Associated with Sjögren’s Syndrome Immunopathogenesis
Local and systemic insulin resistance resulting from hepatic activation of IKK-ßand NF-? B.
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
Long-term incubation with proteasome inhibitors (PIs) induces IκBα degradation via the lysosomal pathway in an IκB kinase (IKK)-dependent and IKK-independent …
Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-κB in endothelial cells
LPS induces Rac1-dependent reactive oxygen species (ROS) formation and coordinates TNF-α secretion through IKK regulation of NF-kappa B
LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
LRRC14 attenuates Toll-like receptor-mediated NF-κB signaling through disruption of IKK complex
Lyn kinase controls TLR4-dependent IKK and MAPK activation modulating the activity of TRAF-6/TAK-1 protein complex in mast cells
Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor α-and interleukin-1β-induced IKK/NF-κB and JNK/AP-1 activation
Maintenance of constitutive NF-κB activity by glycogen synthase kinase-3 and IKK in pancreatic cancer
Malabaricone C suppresses lipopolysaccharide-induced inflammatory responses via inhibiting ROS-mediated Akt/IKK/NF-κB signaling in murine macrophages
MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-κB-dependent proliferative advantage and resistance against FAS-induced cell death in …
MALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activation
Marasmius oreades substances block NF-κB activity through interference with IKK activation pathway
Mature T cells depend on signaling through the IKK complex
Measurement of IKK activity in primary rat T cells: rapid activation and inactivation
MECHANIMS OF GENE ACTIVATION BY PATHOGENIC AND INFLAMMATORY STIMULI THROUGH IKK AND NF-KB PATHWAYS: 177
Mechanism of IKK activation by the Kaposi’s sarcoma-associated herpesvirus protein vFLIP and its cellular homologues
Mechanism underlying IKK activation mediated by the linear ubiquitin chain assembly complex (LUBAC)
Mechanisms by which the IKK-related Kinases Affect Energy Expenditure.
Mechanisms of IKK/NF-κB dependent diabetes development
Mechanisms of liver injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways
MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infection
Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation
Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK 𝛽 Action in a Fiber-Type Specific Manner
Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κ B activation
Methods for identifying and using IKK inhibitors
Micrococci and peptidoglycan activate TLR2→ MyD88→ IRAK→ TRAF→ NIK→ IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8
Migration and proliferation of human mesenchymai stem cells from patients with systemic lupus erythematosus mediated by IKK-β
miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β
miR-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of IKK-β
miR‐429 is involved in regulation of NF‐κBactivity by targeting IKK β and suppresses oncogenic activity in cervical cancer cells
MiR‐503 targets PI3K p85 and IKK‐β and suppresses progression of non‐small cell lung cancer
Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell death
Miyabenol A inhibits LPS-induced NO production via IKK/IκB inactivation in RAW 264.7 macrophages: possible involvement of the p38 and PI3K pathways
MMP9 reinforces radiation-induced delayed invasion and metastasis of neuroblastoma through second-signaling positive feedback with NFκB via both ERK and IKK …
Modulation of cellular IKK complexes by human Adenovirus Type 5
Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 …
Modulation of IKK/NF-B signaling iin pancreatic ß-cells induces diabetes
Modulation of NF‐κB activation in Theileria annulata‐infected cloned cell lines is associated with detection of parasite‐dependent IKK signalosomes and disruption of …
Modulation of nuclear factor-kb (NF-kb), IkB kinase (IKK) and inducible nitric oxide synthase (iNOS) via proinflammatory cytokines with adjuvant selenomethionine (Se …
Modulation of the SMRT co-repressor by IKK: Requirement for NF-κB transcription and cell survival
Molecular cloning and characterization of an IKK homologue from amphioxus (Branchiostoma belcheri)
MOLECULAR CLONING, EXPRESSION ANALYSIS AND CHARACTERIZATION OF GRASS CARP IKK-BETA
Molecular exploration of age-related NF-κB/IKK downregulation by calorie restriction in rat kidney
Molecular mechanism of inhibitor of κ B kinase (IKK) complex activation by inducible phosphorylation and ubiquitination upon T cell receptor (TCR) …
Multiple functions of the IKK-related kinase IKKε in interferon-mediated antiviral immunity
Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL’s in vitro transforming …
Mutation of cysteine 46 in IKK-beta increases inflammatory responses
Myosin motor Myo1c and its receptor NEMO/IKK-γ promote TNF-α–induced serine307 phosphorylation of IRS-1
Myricetin attenuates lipopolysaccharide‐stimulated activation of mouse bone marrow‐derived dendritic cells through suppression of IKK/NF‐κB and MAPK signalling …
Myricetin attenuates lipopolysaccharideâ stimulated activation of mouse bone marrowâ derived dendritic cells through suppression of IKK/NFâ κB and MAPK …
Natural Molecules as IKK α/β Inhibitors useful in the Treatment of Inflammation
Negative feedback loops: nutrient starvation employs a new tr (IKK) to inhibit PI3K
NEMO (IKK [gamma]) Mutation Can Be Associated With Opportunistic Infection Without Impairing TLR Function
NEMO binding domain of IKK‐2 encompasses amino acids 735–745
NEMO/IKK γ regulates an early NF-κ B-independent cell-death checkpoint during TNF signaling
Neuroprotective potential of the NF-κB inhibitor peptide IKK-NBD in cerebral ischemia-reperfusion injury
New functions of NEMO, the regulatory subunit of IKK
New IKK inhibitors: Synthesis of new imidazo [1, 2-a] quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors
NF-kappaB targeting by way of IKK inhibition sensitizes lung cancer cells
NF-kappaB/IKK-2 Signalling Is Not Required For Cigarette Smoke-Induced Airway Inflammation
NF-κB and IKK as Key Mediators of Inflammation and Oncogenic Progression
NF-κB and IKK as therapeutic targets in cancer
NF-κB Induction by Bisperoxovanadium Compounds Requires CD45, p36LAT, PKC, and IKK Activity and Exhibits Kinetics of Activation Comparable to Those of TCR …
NF-κB Signal Transduction by IKK Complexes
NF-κB targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL
NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
NF‐κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK‐related kinase
NF‐κB activation mechanism of 4‐hydroxyhexenal via NIK/IKK and p38 MAPK pathway
NF‐κB activation through IKK‐i‐dependent I‐TRAF/TANK phosphorylation
NFκB inhibition and more: A side-by-side comparison of the inhibitors of IKK and proteasome
Nitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90
NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK
NOffl~-IKK/AND
Noise-induced oscillatory shuttling of NF-{\kappa} B in a two compartment IKK-NF-{\kappa} BI {\kappa} B-A20 signaling model
Notch-1 activates estrogen receptor alpha-dependent transcription via IKK alpha
Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells
Novel components of the IKK complex
Novel cross-talk within the IKK family controls innate immunity
Novel IKK inhibitors: β-carbolines
Novel splicing mutation in the NEMO (IKK‐gamma) gene with severe immunodeficiency and heterogeneity of X‐chromosome inactivation
Novel tight-binding inhibitory factor-κB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local …
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer
O019 TLR4-mediated IKK and MAPK activation is regulated by differential post-translational modification of TAK1
Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-κB pathway
Osteopontin induces nuclear factor κB-mediated promatrix metalloproteinase-2 activation through IκBα/IKK signaling pathways, and curcumin (diferulolylmethane) …
Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis
Overexpression of the tumor suppressor IKK alpha prevents development of malignant carcinomas and metastases in skin
OXIDANT-INDUCED PRIMING OF THE MACROPHAGE INVOLVES TYROSINE PHOSPHORYLATION OF IKK VIA A SRC KINASE PATHWAY: 164
Oxidative stress transiently decreases the IKK complex (IKKα, β, and γ), an upstream component of NF-κB signaling, after transient focal cerebral ischemia in mice
Oyster IKK‐like protein shares structural and functional properties with its mammalian homologues
P132 The human dead-box helicase 3 couples IKK-epsilon to IRF3 activation
p27 Kip1 Attenuates Endotoxin-Induced Cardiac Dysfunction Through Inhibition of the IKK-NF-kB Pathway
p38 MAPK, IKK-2 and Oxidative Stress Regulate Histone 3 Serine 10 Phosphorylation in Blood Monocytes and Alveolar Macrophages.
p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO
P52. The IKK inhibitors celastrol and parthenolide inhibit breast cancer cell proliferation and migration in vitro and osteolytic bone metastasis in vivo
p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche
p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation
PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer
Peptides Corresponding to the N and C Termini of IκB-α,-β, and-ε as Probes of the Two Catalytic Subunits of IκB Kinase, IKK-1 and IKK-2
Periodontitis modulates insulin signaling, c-Jun N-terminal kinase activity, IKK activity, and insulin receptor substrate-1 ser 307 phosphorylation in muscle and …
Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death
Pharmacological inhibition and silencing of classical IKK-NF-κB pathway by siRNA sensitizes cancer cells to doxorubicin
Phosphorylation of H3 serine 10 by IKK α governs cyclical production of ROS in estrogen-induced transcription and ensures DNA wholeness
Phosphorylation of serine 68 in the IκB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-α-induced NF …
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation
PHYSIOLOGICAL AND PATHOLOGICAL ACTIVATION OF IKK AND IKK-RELATED KINASES
Piceatannol prevents lipopolysaccharide (LPS)‐induced nitric oxide (NO) production and nuclear factor (NF)‐κB activation by inhibiting IκB kinase (IKK)
PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl …
PKC-zeta associates and phosphorylates IKK-α/β in breast cancer cells
PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1
POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF-κ B pathway
Potential biomarkers involving IKK/RelA signal in early stage non‐small cell lung cancer
Pregnancy weight gain limitation by a supervised nutritional program influences placental NF-κB/IKK complex expression and oxidative stress
Preliminary study of inhibition of human Tenon’s capsule fibroblasts in vitro by RNA interference targeting IKK-beta
Probing the effect of IKK on FOXO3: a regulatory mechanism of apoptosis and autophagy in chemoresistance
Profilin–PTEN interaction suppresses NF-κB activation via inhibition of IKK phosphorylation
Profiling expression of NF-κB signaling target genes in IKK-2 inhibitor treated pterygium and conjunctiva fibroblast cells
Programming cellular gene expression by IKK mediated NF-κB activation
Protection from experimental colitis by theaflavin‐3,3′‐digallate correlates with inhibition of IKK and NF‐κB activation
Protective effect of Aplysin on IKK/NF-kB signaling pathway and related cytokines in rats exposed to ethanol
Protective effect of Ginkgolids (A+ B) is associated with inhibition of NIK/IKK/IκB/NF-κB signaling pathway in a rat model of permanent focal cerebral ischemia
Protective effects of organic acid component from Taraxacum mongolicum Hand.-Mazz. against LPS-induced inflammation: regulating the TLR4/IKK/NF-κB signal …
Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation
Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt …
Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways
PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IκB kinase β (IKK-β)
QSAR studies on imidazothienopyrazines as IKK‐β inhibitors: from 2D to 3D
R‐roscovitine sensitizes anaplastic thyroid carcinoma cells to TRAIL‐induced apoptosis via regulation of IKK/NF‐κB pathway
Rac1 and PAK1 are upstream of IKK‐ε and TBK‐1 in the viral activation of interferon regulatory factor‐3
RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
Real-time imaging of differential ligand-induced IKK activation and impact on the IκBα: NF-κB negative feedback loop within living cells and mice
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
Recursion formulae for IKK system with two hierarchies
Refrigerants-in the focus of attention at the IKK. Kaeltemittel-Messethema Nummer eins
Regional susceptibility to TNF-α induction of murine brain inflammation via classical IKK/NF-κB signalling
Regulation and function of IKK and IKK-related kinases
Regulation of BH3-only proteins by IKK, downstream of beta-common receptor signalling
Regulation of bone metastasis by the IKK [beta]/FoxO3a axis
Regulation of cell death and autophagy by IKK and NF‐κB: critical mechanisms in immune function and cancer
Regulation of expression of Bcl-3 proto-oncogene by IKK ϵ
Regulation of I-kappa-B kinase (IKK) Pathway by CARMA 1• Bcl-10• MALT-1 (CBM) Complex Promotes SNARE Complex Formation and Secretion in Platelets
Regulation of IKK
Regulation of IL-8 expression by IKK and histone deacetylases in ovarian cancer
Regulation of IκB kinase (IKK) complex by IKKγ-dependent phosphorylation of the T-loop and C terminus of IKKβ
Regulation of IκB kinase (IKK) γ/NEMO function by IKKβ-mediated phosphorylation
Regulation of Survival by IKK (epsilon) in Inflammatory Breast Cancer Involves EpCAM
Regulation of tumor necrosis factor receptor-1 and the IKK-NF-κB pathway by LDL receptor–related protein explains the antiinflammatory activity of this receptor
Relationship of Inhibitory Effects of Dichroa febrifuga and on the Activation of
Requirement of Hsp90 activity for I κ B kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κ B activation
Resistin up-regulates COX-2 expression via TAK1-IKK-NF-κB signaling pathway
Retroviral oncoprotein Tax deregulates NF‐κB by activating Tak1 and mediating the physical association of Tak1–IKK
RhoA regulation of NF-κB activation is mediated by Cox-2-dependent feedback inhibition of IKK in kidney epithelial cells
Rituximab-Mediated Inhibition of the Constitutive NIK/IKK/IκB/NF-κB Signaling Pathway in Non-Hodgkin’s Lymphoma (NHL) B-Cell Lines: Role in Chemo-Sensitization …
Role of cAMP and IKK-2-dependent signaling in the realization of growth potential of mesenchymal progenitor cells
Role of cAMP-and IKK-2-Dependent Signaling Pathways in Functional Stimulation of Mesenchymal Progenitor Cells with Alkaloid Songorine.
Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways
Role of IKK and oscillatory NFκB kinetics in MMP‐9 gene expression and chemoresistance to 5‐fluorouracil in RKO colorectal cancer cells
Role of IKK-alpha in the EGFR Signaling Regulation
Role of IKK/NF-κB signaling in extinction of conditioned place aversion memory in rats
Role of PI3K/AKT/IKK pathway in NFκB-and β-catenin-dependent transcription in colorectal cancer
Role of the adaptor protein CIKS in the activation of the IKK complex
Role of the COP9 Signalosome and IKK Complexes in Atherosclerosis
Role of the IKK complex during liver regeneration
Roles of Akt/PKB and IKK complex in constitutive induction of NF-κB in hepatocellular carcinomas of transforming growth factor α/c-myc transgenic mice
Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-κB in breast cancer
Roles of IKK-β, IRF1, and p65 in the activation of chemokine genes by interferon-γ
Rosiglitazone inhibits hepatic insulin resistance induced by chronic pancreatitis and IKK-β/NF-κB expression in liver
Rosmarinic acid as a downstream inhibitor of IKK‐β in TNF‐α‐induced upregulation of CCL11 and CCR3
S 2-38: Activation and homeostatic control of IKK and NF-kB in oncogenesis and innate immunity
Salicylate Inhibition of IKK [Beta](I [Kappa] B Kinase) Reverses Insulin Resistance in Zucker (fa/fa) Rats
Saturated FFA Induced NF-κB Activation Is Independent of IKK/IκBα in Aortic Endothelial Cells
Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide …
Screening of specific SiRNA targeting IKKβ in human keloid fibroblasts and construction of IKK β-siRNA expression vector☆
Segregation of NF-κ B activation through NEMO/IKK γ by Tax and TNF α: implications for stimulus-specific interruption of oncogenic signaling
Selective degradation of the IκB kinase (IKK) by autophagy
Selective Retinoids That Inhibit IKK as Chemotherapeutic Agents Against Estrogen-Independent Breast Cancer Cells
Selenium Compounds Inhibit IB Kinase (IKK) and Nuclear Factor-B (NF-B) in Prostate Cancer Cells1
Selenium Compounds Inhibit IκB Kinase (IKK) and Nuclear Factor-κB (NF-κB) in Prostate Cancer Cells 1 Supported by Department of Defense Prostate Cancer …
Sensitivity analysis of a computational model of the IKK-NF-{\kappa} BI {\kappa} B {\alpha}-A20 signal transduction network
Sensitivity analysis of parameters controlling oscillatory signalling in the NF-κB pathway: the roles of IKK and IκBα
Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation
Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF-κB-dependent mechanism
Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway
Signal Processing by the Control Cycle of the IKK Kinase in the NFκB Signaling Axis
Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal …
Signaling by the Mpl receptor involves IKK and NF‐κB
Signaling pathways leading to the activation of IKK and MAPK by thymosin α1
Silencing of the cell cycle checkpoint gene 14‐3‐3σ in basal cell carcinomas correlates with reduced expression of IKK‐α
Simultaneous inhibition of Rac1 and IKK pathways sensitizes lung cancer cells to TNFα-mediated apoptosis
Small molecule inhibitors of IKK kinase activity
Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases
Stable reconstitution of IKK-deficient mouse embryonic fibroblasts
Statins prevent NF-κB transactivation independently of the IKK-pathway in human endothelial cells
StIKKing together: do multiple IKK pathways cooperate in the DNA-damage response?
Stimulation of IKK-γ oligomerization by the human T-cell leukemia virus oncoprotein Tax
Stimulus specificity of gene expression programs determined by temporal control of IKK activity
Structure and dynamics of the kinase IKK-β–A key regulator of the NF-kappa B transcription factor
Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site
SUBSTITUTED THIOPHENECARBOXAMIDES AS IKK-BETA SERINE-, THREONINE-PROTEIN KINASE INHIBITORS.
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells
Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase …
SUMOyla ted CPAP is required for IKK-med iated NF-jB activa tion and enhances HBx-induce d NF-jB signal ing in HCC
SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC
Suppression by IKK-2 Inhibitor of IL-1-Induced Collagen Degradation by Corneal Fibroblasts
Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated
…
Suppression of NF-κ B and NF-κ B-regulated gene expression by sulforaphane and PEITC through I κ B α, IKK pathway in human prostate cancer PC-3 cells
Suppression of NF-κB and NF-κB-regulated gene expression by apigenin through IκBα and IKK pathway in TRAMP mice
Suppression of TNFα‐mediated NFκb activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells
Suppressor of IKK epsilon (SIKE) acts as a bridge between innate immune signalling pathway and cytoskeletal rearrangements
Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells
Sustained activation of protein kinase C downregulates nuclear factor-κB signaling by dissociation of IKK-γ and Hsp90 complex in human colonic epithelial cells
Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging
Synergistic benefit in inflammatory arthritis by targeting IKK∊ and IFNβ
Synergy between rhBMP-2 and IKK-inhibitor PS-1145 delivered via a porous biodegradable polymer implant
Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors
Synthesis and structure–activity relationship of imidazo (1, 2-a) thieno (3, 2-e) pyrazines as IKK-β inhibitors
Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: improvement of in vitro activity
Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents
Synthesis of C‐14 and C‐13, H‐2‐labeled IKK inhibitor: [14C] and [13C4,D3]‐N‐(6‐chloro‐7‐
methoxy‐9H‐pyrido[3,4‐b]indol‐
8‐yl)‐2‐methyl‐3 …
Synthesis of C‐14‐labeled novel IKK inhibitor: 2‐[14C]‐N‐(6‐chloro‐9H‐pyrido [3,4‐b]indol‐8‐yl)‐3‐
pyridinecarboxamide
Synthesis of inhibitors of the IKK-complex for the treatment of prostate cancer
Systematic characterization by mass spectrometric analysis of phosphorylation sites in IRF-3 regulatory domain activated by IKK-i
T cell receptor signals to NF-κB are transmitted by a cytosolic p62-Bcl10-Malt1-IKK signalosome
TAK 1 adaptor proteins, TAB 2 and TAB 3, link the signalosome to B‐cell receptor‐induced IKK activation
TAK-ling IKK activation:“Ub” the judge
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation
TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation
TAK1‐binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL‐1 signaling pathway
Tamoxifen reduces infiltration of inflammatory cells, apoptosis and inhibits IKK/NF-kB pathway after spinal cord injury in rats
Tanshinone IIA inhibits LPS-induced NF-κB activation in RAW 264.7 cells: Possible involvement of the NIK–IKK, ERK1/2, p38 and JNK pathways
Targeting IKK and NF-κB for therapy
Targeting IKK in Basal-Like Breast Tumors as a Therapeutic Approach
Targeting IKK Inhibits Multiple Myeloma (MM) Cell Growth in the Bone Marrow Microenvironment.
Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats
Targeting transcription factor NFκB: comparative analysis of proteasome and IKK inhibitors
Tautomycetin suppresses the TNFα/NF-κB pathway via inhibition of IKK activation
Tectorigenin regulates adipogenic differentiation and adipocytokines secretion via PPAR γ and IKK/NF-κ B signaling
Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression
Temporal encoding and homeostatic control in the IKK-kappaNF-kappaB signaling system
Tendon Healing In Vitro: Activation of NIK, IKK α, IKK β, and NF-κB Genes in Signal Pathway and Proliferation of Tenocytes
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling
Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation
TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
TGF-β promotes cancer progression through the xIAP: TAB1: TAK1: IKK axis in mammary epithelial cells
The adipocyte IKK/NFkappaB pathway: a therapeutic target for insulin resistance.
The anti-death machinery in IKK/NF-κB signaling
The anti-inflammatory role for IkappaB kinase (IKK) beta through inhibition of ‘classical’macrophage activation
The beginning of the end: IκB kinase (IKK) and NF-κB activation
The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation
The catalytic subunits of IκB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers
The discovery of 2-amino-3, 5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis
The effect of smoking and smoking cessation on the phosphorylation of IKK-ß in type 2 diabetic rats
The HSP 90 inhibitor NVP‐AUY 922‐AG inhibits the PI 3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells
The IkB kinase complex (IKK) contains two kinase subunits, IKKa and IKKb, necessary for IkB phosphorylation and NF-kB activation
The IKK complex & TNFR1 signaling to NF-κB
The IKK complex contributes to the induction of autophagy
The IKK complex contributes to the induction of autophagy
The IKK Complex, a Central Regulator of NF-kB Activation
The IKK complex, a central regulator of NF-κB activation
The IKK complex: an integrator of all signals that activate NF-κB?
The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors
The IKK inhibitor BMS-345541 affects multiple mitotic cell cycle transitions
The IKK inhibitor BMS345541 affects aurora kinase expression in human melanoma
The IKK Inhibitor PS1145 Allows to Overcome Imatinib Resistance.
The IKK kinases: operators of antiviral signaling
The IKK NF-κB system: a treasure trove for drug development
The IKK subunit of I B kinase (IKK) is essential for nuclear factor B activation and prevention of apoptosis
The IKK-2/IκBα/NF-κB Pathway Plays a Key Role in the Regulation of CCR3 and eotaxin-1 in Fibroblasts A CRITICAL LINK TO DERMATITIS IN IκBα-DEFICIENT MICE
The IKK-NF-κB pathway: a source for novel molecular drug targets in pain therapy?
The IKK-related kinases: from innate immunity to oncogenesis
The IKK‐neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase‐dependent activation‐induced cell death
The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer
The IKK/nf-κb pathway
The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
The IKK/NFkB & B-catenin pathway is critical for migration, invasion and metastasis in colorectal cancer
The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
The influence of the signal dynamics of activated form of IKK on NF‐κB and anti‐apoptotic gene expressions: A systems biology approach
The information system on cancer mortality and district characteristics (IKK) of the TUeV Rheinland
The interplay of IKK, NF‐κB and RIPK 1 signaling in the regulation of cell death, tissue homeostasis and inflammation
The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling
The IκB Kinase (IKK) and the Control of Immunity, Inflammation and Cancer
The IκB kinase (IKK) complex as a critical regulator of immune responses
The IκB kinase (IKK) complex is tripartite and contains IKKγ but not IKAP as a regular component
The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis
The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
The IкB Kinase (IKK) Complex
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
The N-terminus of PKR is responsible for the activation of the NF-κB signaling pathway by interacting with the IKK complex
The NF-κ B pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance
The NF-κB-independent functions of IKK subunits in immunity and cancer
The physical association of protein kinase Cθ with a lipid raft-associated inhibitor of κB factor kinase (IKK) complex plays a role in the activation of the NF-κB cascade …
The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity
The prosurvival IKK-related kinase IKKε integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine
The role of IKK in constitutive activation of NF-κB transcription factor in prostate carcinoma cells
The Role of IKK in Interferon–Dependent Signaling
The role of IKK-induced NF-kB1 p105 proteolysis in T lymphocytes
The role of the IKK complex in viral infections
The role of the IKK-2/NF-kB signaling in cigarette smoke-induced airway inflammation
The role of the IKK/NF-kappa B signaling pathways in the extinction of auditory fear condition
The role of the non-canonical IKK complex in glioblastoma multiforme
THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS
The roles of APC2 and IKK in the regulation of beta-catenin signaling.
The shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral …
The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt–IKK–NF-κB–MMP-9 axis
The use of IKK inhibitor as a lymphocyte depleting agent (47.4)
The zinc transporter SLC39A8 is a negative feedback regulator of NF-κB through zinc-mediated inhibition of IKK
The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
Theileria-induced constitutive IKK activation is independent of functional Hsp90
Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study
Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study Animal
THIENOPYRIDAZINES AS IKK INHIBITORS
Thiophene carboxamides as inhibitors of the enzyme IKK-2
THU0024 Anti-Inflammatory Inhibitors Targeting Jak and IKK Have An Anabolic Effect on Type II Collagen Turnover ex Vivo
TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6
Timosaponin B-II Ameliorates Palmitate-Induced Insulin Resistance and Inflammation via IRS-1/PI3K/Akt and IKK/NF-B Pathways
TLR7 agonist induced repression of hepatocellular carcinoma via the TLR7-IKK-NF-κB-IL6 signaling pathway
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
TNF-α modulation of intestinal tight junction permeability is mediated by NIK/IKK-α axis activation of the canonical NF-κB pathway
TNF-α-induced loss of IKK-α in skeletal muscle: implications for skeletal muscle oxidative phenotype
TNFR1 determines progression of chronic liver injury in the IKK γ/Nemo genetic model
TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification
TNFα induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways
Tracking the road from inflammation to cancer: the critical role of IkappaB kinase (IKK)
TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice
TRAF2 plays a critical role in maintaining lymphocyte homeostasis by regulating the basal activities of IKK and caspase-8
TRAF2 suppresses basal IKK activity in resting cells and TNFα can activate IKK in TRAF2 and TRAF5 double knockout cells
TRAF5-mediated Tax ubiquitination modulates IKK phosphorylation but not binding to NEMO
Transient activation of NF-κ B through a TAK1/IKK kinase pathway by TGF-β 1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor …
Triggering the interferon antiviral response through an IKK-related pathway
Triggering the Interferon Antiviral Response Through an IKK-Related Pathway
TRIM22 can activate the noncanonical NF-κ B pathway by affecting IKK α
Tumor necrosis factor α stimulates endothelin-1 synthesis in rat hepatic stellate cells in hepatic wound healing through a novel IKK/JNK pathway
Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
Tumor necrosis factor α-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK
Tumor necrosis factor-α-induced IKK phosphorylation of NF-κB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
Tunable signal processing through a kinase control cycle: the IKK signaling node
Two coordinated mechanisms underlie TNFα-induced immediate and delayed IKK activation
Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes
Ubiquitin-mediated activation of TAK1 and IKK
Ubiquitin, TAK1 and IKK: is there a connection?
Ubiquitination in signaling to and activation of IKK
Ubiquitination-Dependent Activation of IKK
Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome
Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB
Upregulation of IKK α/IKK β by integrin-linked kinase is required for HER2/neu-induced NF-κ B antiapoptotic pathway
Use of molecular imaging to quantify response to IKK‐2 inhibitor treatment in murine arthritis
Using RNA interference in lung cancer cells to target the IKK-NF-κB pathway
Using structural analysis to investigate the function of Suppressor of IKK-epsilon (SIKE)
Vaccinia virus E3L protein inhibits type I IFN induction throughthe RLH pathway and associates with MDA-5 and IKK-ϵ
Validation of the anti-inflammatory properties of small-molecule IκB kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative …
Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism
Water extract of Cynanchi atrati Radix regulates inflammation and apoptotic cell death through suppression of IKK-mediated NF-κB signaling
Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex
WNT5A regulates chondrocyte differentiation through differential use of the CaN/NFAT and IKK/NF-κB pathways
α-Catulin, a Rho signalling component, can regulate NF-κB through binding to IKK-β, and confers resistance to apoptosis
β-Adrenergic stimulation induces interleukin-18 expression via β2-AR, PI3K, Akt, IKK, and NF-κB
β-Carboline alkaloid suppresses NF-κB transcriptional activity through inhibition of IKK signaling pathway
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