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Hypocretin Orexin

  1. HYPOCRETIN (OREXIN ) deficiency in human narcolepsy
  2. HYPOCRETIN (OREXIN ) loss in Parkinsonโ€™s disease
  3. Neurons containing HYPOCRETIN (OREXIN ) project to multiple neuronal systems
  4. Behavioral correlates of activity in identified HYPOCRETIN /OREXIN neurons
  5. HYPOCRETIN (OREXIN ) loss in Alzheimerโ€™s disease
  6. The HYPOCRETIN /OREXIN system
  7. HYPOCRETIN (OREXIN ) cell loss in Parkinsonโ€™s disease
  8. Release of HYPOCRETIN (OREXIN ) during waking and sleep states
  9. HYPOCRETIN (OREXIN ): role in normal behavior and neuropathology
  10. The HYPOCRETIN /OREXIN ligandโ€“receptor system: implications for sleep and sleep disorders
  11. HYPOCRETIN /OREXIN in arousal and stress
  12. A role for HYPOCRETIN (OREXIN ) in male sexual behavior
  13. Hypothalamic HYPOCRETIN (OREXIN ): robust innervation of the spinal cord
  14. A role for HYPOCRETIN /OREXIN in motivation
  15. The sleep disorder canine narcolepsy is caused by a mutation in the HYPOCRETIN (OREXIN ) receptor 2 gene
  16. The HYPOCRETIN /OREXIN system: an increasingly important role in neuropsychiatry
  17. Loss of HYPOCRETIN (OREXIN ) neurons with traumatic brain injury
  18. HYPOCRETIN /OREXIN excites HYPOCRETIN neurons via a local glutamate neuronโ€”a potential mechanism for orchestrating the hypothalamic arousal system
  19. The HYPOCRETIN (OREXIN ) system: from a neural circuitry perspective
  20. Leptin receptor-and STAT3-immunoreactivities in HYPOCRETIN /OREXIN neurones of the lateral hypothalamus.
  21. CSF HYPOCRETIN /OREXIN levels in narcolepsy and other neurological conditions
  22. HYPOCRETIN /OREXIN contributes to the expression of some but not all forms of stress and arousal
  23. IGFBP3 colocalizes with and regulates HYPOCRETIN (OREXIN )
  24. HYPOCRETIN /OREXIN overexpression induces an insomnia-like phenotype in zebrafish
  25. The HYPOCRETIN /OREXIN system in health and disease
  26. HYPOCRETIN (OREXIN ) regulation of sleep-to-wake transitions
  27. Low cerebrospinal fluid HYPOCRETIN (OREXIN ) and altered energy homeostasis in human narcolepsy
  28. HYPOCRETIN (OREXIN ) activation and synaptic innervation of the locus coeruleus noradrenergic system
  29. HYPOCRETIN (OREXIN ) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area
  30. Sleep, sleep disorders and HYPOCRETIN (OREXIN )
  31. HYPOCRETIN /OREXIN , sleep and narcolepsy
  32. The wake-promoting HYPOCRETIN โ€“OREXIN neurons are in an intrinsic state of membrane depolarization
  33. Wake-promoting and sleep-suppressing actions of HYPOCRETIN (OREXIN ): basal forebrain sites of action
  34. The HYPOCRETIN /OREXIN system mediates the extinction of fear memories
  35. Identification and functional analysis of mutations in the HYPOCRETIN (OREXIN ) genes of narcoleptic canines
  36. Regulation of HYPOCRETIN (OREXIN ) expression in embryonic zebrafish
  37. Localized loss of HYPOCRETIN (OREXIN ) cells in narcolepsy without cataplexy
  38. HYPOCRETIN /OREXIN disturbances in neurological disorders
  39. A commentary on the neurobiology of the HYPOCRETIN /OREXIN system
  40. Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, HYPOCRETIN /OREXIN
  41. The HYPOCRETIN โ€“OREXIN system regulates cocaine selfโ€administration via actions on the mesolimbic dopamine system
  42. Narp immunostaining of human HYPOCRETIN (OREXIN ) neurons: loss in narcolepsy
  43. HYPOCRETIN (OREXIN ) biology and the pathophysiology of narcolepsy with cataplexy
  44. Predictors of HYPOCRETIN (OREXIN ) deficiency in narcolepsy without cataplexy
  45. Synaptic interaction between HYPOCRETIN (OREXIN ) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and โ€ฆ
  46. HYPOCRETIN (OREXIN ) neuromodulation of stress and reward pathways
  47. HYPOCRETIN /OREXIN depolarizes and decreases potassium conductance in locus coeruleus neurons
  48. Pattern of HYPOCRETIN (OREXIN ) soma and axon loss, and gliosis, in human narcolepsy
  49. Narcolepsy with HYPOCRETIN /OREXIN deficiency, infections and autoimmunity of the brain
  50. HYPOCRETIN /OREXIN and energy expenditure
  51. HYPOCRETIN /OREXIN innervation and excitation of identified septohippocampal cholinergic neurons
  52. Medial vestibular connections with the HYPOCRETIN (OREXIN ) system
  53. Non-sleep effects of HYPOCRETIN /OREXIN
  54. Function and dysfunction of HYPOCRETIN /OREXIN : an energetics point of view
  55. Differential modulation of nociceptive dural input to [HYPOCRETIN ] OREXIN A and B receptor activation in the posterior hypothalamic area
  56. Lateral hypothalamus: early developmental expression and response to HYPOCRETIN (OREXIN )
  57. Adenosine inhibits activity of HYPOCRETIN /OREXIN neurons by the A1 receptor in the lateral hypothalamus: a possible sleep-promoting effect
  58. HYPOCRETIN /OREXIN neurons contribute to hippocampus-dependent social memory and synaptic plasticity in mice
  59. Regulation of synaptic efficacy in HYPOCRETIN /OREXIN -containing neurons by melanin concentrating hormone in the lateral hypothalamus
  60. Direct and indirect inhibition by catecholamines of HYPOCRETIN /OREXIN neurons
  61. The HYPOCRETIN /OREXIN system in sleep disorders: preclinical insights and clinical progress
  62. Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic HYPOCRETIN /OREXIN system
  63. Mapping the HYPOCRETIN /OREXIN neuronal system: an unexpectedly productive journey
  64. Differential target-dependent actions of coexpressed inhibitory dynorphin and excitatory HYPOCRETIN /OREXIN neuropeptides
  65. Sexually dimorphic changes of HYPOCRETIN (OREXIN ) in depression
  66. Fasting activates the nonhuman primate HYPOCRETIN (OREXIN ) system and its postsynaptic targets
  67. HYPOCRETIN /OREXIN : a molecular link between sleep, energy regulation, and pleasure
  68. HYPOCRETIN /OREXIN type 1 receptor in brain: role in cardiovascular control and the neuroendocrine response to immobilization stress
  69. Decreased brain histamine content in HYPOCRETIN /OREXIN receptor-2 mutated narcoleptic dogs
  70. HYPOCRETIN /OREXIN โ€and melaninโ€concentrating hormoneโ€expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide โ€ฆ
  71. Organization of HYPOCRETIN /OREXIN efferents to locus coeruleus and basal forebrain arousalโ€related structures
  72. HYPOCRETIN /OREXIN and narcolepsy: new basic and clinical insights
  73. Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse HYPOCRETIN /OREXIN neurons
  74. Reduction of plasma leptin levels and loss of its circadian rhythmicity in HYPOCRETIN (OREXIN )-deficient narcoleptic humans
  75. Metabolic state signalling through central HYPOCRETIN /OREXIN neurons
  76. Recent advances in understanding the roles of HYPOCRETIN /OREXIN in arousal, affect, and motivation
  77. Mitigation of murine focal cerebral ischemia by the HYPOCRETIN /OREXIN system is associated with reduced inflammation
  78. Exclusive postsynaptic action of HYPOCRETIN โ€“OREXIN on sublayer 6b cortical neurons
  79. A role for HYPOCRETIN /OREXIN in metabolic and sleep abnormalities in a mouse model of non-metastatic breast cancer
  80. The HYPOCRETIN /OREXIN system: implications for drug reward and relapse
  81. Alertness and feeding behaviors in ADHD: does the HYPOCRETIN /OREXIN system play a role?
  82. GABAB receptorโ€mediated modulation of HYPOCRETIN /OREXIN neurones in mouse hypothalamus
  83. Excitatory action of HYPOCRETIN /OREXIN on neurons of the central medial amygdala
  84. HYPOCRETIN /OREXIN suppresses corticotroph responsiveness in vitro
  85. Optogenetic probing of fast glutamatergic transmission from HYPOCRETIN /OREXIN to histamine neurons in situ
  86. HYPOCRETIN /OREXIN in fish physiology with emphasis on zebrafish
  87. HYPOCRETIN /OREXIN selectively increases dopamine efflux within the prefrontal cortex: involvement of the ventral tegmental area
  88. Age-related decline in HYPOCRETIN (OREXIN ) receptor 2 messenger RNA levels in the mouse brain
  89. Stereological analysis of the hypothalamic HYPOCRETIN /OREXIN neurons in an animal model of depression
  90. HYPOCRETIN /OREXIN preferentially activates caudomedial ventral tegmental area dopamine neurons
  91. Circadian-dependent and circadian-independent behavioral actions of HYPOCRETIN /OREXIN
  92. Comparison of melanin-concentrating hormone and HYPOCRETIN /OREXIN mRNA expression patterns in a new parceling scheme of the lateral hypothalamic zone
  93. Direct and indirect excitation of laterodorsal tegmental neurons by HYPOCRETIN /OREXIN peptides: implications for wakefulness and narcolepsy
  94. Effects of ambient temperature on sleep and cardiovascular regulation in mice: the role of HYPOCRETIN /OREXIN neurons
  95. HYPOCRETIN /OREXIN signaling in the hypothalamic paraventricular nucleus is essential for the expression of nicotine withdrawal
  96. Differential distribution of HYPOCRETIN (OREXIN ) and melaninโ€concentrating hormone in the goldfish brain
  97. A mathematical model of homeostatic regulation of sleep-wake cycles by HYPOCRETIN /OREXIN
  98. ฮผ-Opioid receptor-mediated depression of the hypothalamic HYPOCRETIN /OREXIN arousal system
  99. HYPOCRETIN (OREXIN ) enhances neuron activity and cell synchrony in developing mouse GFPโ€expressing locus coeruleus
  100. HYPOCRETIN (OREXIN ) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1* 0602 status
  101. A brief history of HYPOCRETIN /OREXIN and narcolepsy
  102. HYPOCRETIN /OREXIN regulation of dopamine signaling and cocaine self-administration is mediated predominantly by HYPOCRETIN receptor 1
  103. A role for HYPOCRETIN /OREXIN receptor-1 in cue-induced reinstatement of nicotine-seeking behavior
  104. HYPOCRETIN /OREXIN and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia
  105. HYPOCRETIN /OREXIN deficiency decreases cocaine abuse liability
  106. P2X2R purinergic receptor subunit mRNA and protein are expressed by all hypothalamic HYPOCRETIN /OREXIN neurons
  107. HYPOCRETIN (OREXIN ) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need
  108. Increased heart rate variability but normal resting metabolic rate in HYPOCRETIN /OREXIN -deficient human narcolepsy
  109. Reinstatement of cocaine seeking by HYPOCRETIN (OREXIN ) in the ventral tegmental area: independence from the local corticotropin-releasing factor network
  110. The number of hypothalamic HYPOCRETIN (OREXIN ) neurons is not affected in Prader-Willi syndrome
  111. The HYPOCRETIN /OREXIN story
  112. HYPOCRETIN /OREXIN regulation of dopamine signaling: implications for reward and reinforcement mechanisms
  113. Analysis of HYPOCRETIN (OREXIN ) antibodies in patients with narcolepsy
  114. Impaired HYPOCRETIN /OREXIN system alters responses to salient stimuli in obese male mice
  115. HYPOCRETIN (OREXIN ) loss and sleep disturbances in Parkinsonโ€™s Disease
  116. Hypothalamic HYPOCRETIN /OREXIN and neuropeptide Y: divergent interaction with energy depletion and leptin
  117. Distribution of HYPOCRETIN -(OREXIN ) immunoreactivity in the central nervous system of Syrian hamsters (Mesocricetus auratus)
  118. Schizophrenia, HYPOCRETIN (OREXIN ), and the thalamocortical activating system
  119. Opposite effects of noradrenaline and acetylcholine upon HYPOCRETIN /OREXIN versus melanin concentrating hormone neurons in rat hypothalamic slices
  120. Neuroendocrine proopiomelanocortin neurons are excited by HYPOCRETIN /OREXIN
  121. The HYPOCRETIN /OREXIN receptor-1 as a novel target to modulate cannabinoid reward
  122. HYPOCRETIN (OREXIN ) induces calcium transients in single spines postsynaptic to identified thalamocortical boutons in prefrontal slice
  123. Neuropeptide Y inhibits HYPOCRETIN /OREXIN neurons by multiple presynaptic and postsynaptic mechanisms: tonic depression of the hypothalamic arousal system
  124. The HYPOCRETIN /OREXIN receptor: therapeutic prospective in sleep disorders
  125. The wake-promoting HYPOCRETIN /OREXIN neurons change their response to noradrenaline after sleep deprivation
  126. Polymorphisms in HYPOCRETIN /OREXIN pathway genes and narcolepsy
  127. Thyrotropin-releasing hormone increases behavioral arousal through modulation of HYPOCRETIN /OREXIN neurons
  128. Modulation of hypothalamic HYPOCRETIN /OREXIN mRNA expression by glucocorticoids
  129. CD4+ T cell autoimmunity to HYPOCRETIN /OREXIN and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy
  130. Optogenetic control of HYPOCRETIN (OREXIN ) neurons and arousal circuits
  131. HYPOCRETIN (OREXIN ) deficiency in narcolepsy and primary hypersomnia
  132. Animal models of narcolepsy and the HYPOCRETIN /OREXIN system: Past, present, and future
  133. Comparison of melanin-concentrating hormone and HYPOCRETIN /OREXIN peptide expression patterns in a current parceling scheme of the lateral hypothalamic zone
  134. HYPOCRETIN (OREXIN ) input to trigeminal and hypoglossal motoneurons in the cat: a double-labeling immunohistochemical study
  135. HYPOCRETIN (OREXIN ) and melanin concentrating hormone loss and the symptoms of Parkinsonโ€™s disease
  136. HYPOCRETIN /OREXIN neuropeptides: participation in the control of sleep-wakefulness cycle and energy homeostasis
  137. Parkinsonโ€™s disease, sleepiness and HYPOCRETIN /OREXIN
  138. Highly specific role of HYPOCRETIN (OREXIN ) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level
  139. The hypothalamic peptidergic system, HYPOCRETIN /OREXIN and vigilance control
  140. HYPOCRETIN /OREXIN peptide signaling in the ascending arousal system: elevation of intracellular calcium in the mouse dorsal raphe and laterodorsal tegmentum
  141. Sex difference in body weight gain and leptin signaling in HYPOCRETIN /OREXIN deficient mouse models
  142. Neurochemical heterogeneity among lateral hypothalamic HYPOCRETIN /OREXIN and melanin-concentrating hormone neurons identified through single-cell gene โ€ฆ
  143. Antidepressant effects of exercise are produced via suppression of HYPOCRETIN /OREXIN and melanin-concentrating hormone in the basolateral amygdala
  144. Comparison of HYPOCRETIN /OREXIN and melanin-concentrating hormone neurons and axonal projections in the embryonic and postnatal rat brain
  145. The development of HYPOCRETIN (OREXIN ) deficiency in HYPOCRETIN /ataxin-3 transgenic rats
  146. Cellular activation of hypothalamic HYPOCRETIN /OREXIN neurons facilitates short-term spatial memory in mice
  147. Systems genomics identifies a key role for HYPOCRETIN /OREXIN receptor-2 in human heart failure
  148. Glucagon-like peptide 1 excites HYPOCRETIN /OREXIN neurons by direct and indirect mechanisms: implications for viscera-mediated arousal
  149. Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit HYPOCRETIN /OREXIN neurons: implications for cannabinoid actions on food intake and โ€ฆ
  150. The HYPOCRETIN /OREXIN system as a target for excessive motivation in alcohol use disorders
  151. Polymorphisms in the vicinity of the HYPOCRETIN /OREXIN are not associated with human narcolepsy
  152. Measurement of HYPOCRETIN /OREXIN content in the mouse brain using an enzyme immunoassay: the effect of circadian time, age and genetic background
  153. Involvement of PLAGL1/ZAC1 in HYPOCRETIN /OREXIN transcription
  154. Effects of HYPOCRETIN /OREXIN cell transplantation on narcoleptic-like sleep behavior in rats
  155. Diurnal fluctuation in the number of HYPOCRETIN /OREXIN and histamine producing: Implication for understanding and treating neuronal loss
  156. HYPOCRETIN /OREXIN and sleep: implications for the pathophysiology and diagnosis of narcolepsy
  157. The HYPOCRETIN /OREXIN neuronal networks in zebrafish
  158. HYPOCRETIN (OREXIN ) replacement therapies
  159. Direct excitation of HYPOCRETIN /OREXIN cells by extracellular ATP at P2X receptors
  160. Distribution of HYPOCRETIN (OREXIN ) immunoreactivity in the feline pons and medulla
  161. Monozygotic twins concordant for narcolepsy-cataplexy without any detectable abnormality in the HYPOCRETIN (OREXIN ) pathway
  162. Group III metabotropic glutamate receptors maintain tonic inhibition of excitatory synaptic input to HYPOCRETIN /OREXIN neurons
  163. HYPOCRETIN /OREXIN involvement in reward and reinforcement
  164. Selective enhancement of synaptic inhibition by HYPOCRETIN (OREXIN ) in rat vagal motor neurons: implications for autonomic regulation
  165. The HYPOCRETIN /OREXIN antagonist almorexant promotes sleep without impairment of performance in rats
  166. Age-related changes in HYPOCRETIN (OREXIN ) immunoreactivity in the cat brainstem
  167. Molecular mechanism of tumour necrosis factor alpha regulates HYPOCRETIN (OREXIN ) expression, sleep and behaviour
  168. Reduced HYPOCRETIN (OREXIN ) levels in dementia with Lewy bodies
  169. From molecule to behavior: HYPOCRETIN /OREXIN revisited from a sex-dependent perspective
  170. Immunohistochemical localization and biochemical characterization of HYPOCRETIN /OREXIN โ€related peptides in the central nervous system of the frog Rana ridibunda
  171. Cocaine abuse and midbrain circuits: Functional anatomy of HYPOCRETIN /OREXIN transmission and therapeutic prospect
  172. HYPOCRETIN /OREXIN knockโ€out mice display disrupted behavioral and dopamine responses to cocaine
  173. HYPOCRETIN /OREXIN and plastic adaptations associated with drug abuse
  174. HYPOCRETIN (OREXIN ) deficiency predicts severe objective excessive daytime sleepiness in narcolepsy with cataplexy
  175. HYPOCRETIN (OREXIN ) in the rat pineal gland: a central transmitter with effects on noradrenalineโ€induced release of melatonin
  176. HYPOCRETIN (OREXIN ) regulates glutamate input to fast-spiking interneurons in layer V of the Fr2 region of the murine prefrontal cortex
  177. HYPOCRETIN /OREXIN increases the expression of steroidogenic enzymes in human adrenocortical NCI H295R cells
  178. Intracellular energy status regulates activity in HYPOCRETIN /OREXIN neurones: a link between energy and behavioural states
  179. Transgenic Archaerhodopsin-3 expression in HYPOCRETIN /OREXIN neurons engenders cellular dysfunction and features of type 2 narcolepsy
  180. Feeding behavior: HYPOCRETIN /OREXIN neurons act between food seeking and eating
  181. Embryonic ethanol exposure affects the early development, migration, and location of HYPOCRETIN /OREXIN neurons in zebrafish
  182. The role of the neuropeptide S system in addiction: focus on its interaction with the CRF and HYPOCRETIN /OREXIN neurotransmission
  183. Repeated in vivo exposure of cocaine induces longโ€lasting synaptic plasticity in HYPOCRETIN /OREXIN โ€producing neurons in the lateral hypothalamus in mice
  184. Rapid and preferential activation of Fos protein in HYPOCRETIN /OREXIN neurons following the reversal of dehydrationโ€anorexia
  185. Clinical implications of basic research: The role of HYPOCRETIN /OREXIN neurons in the central autonomic network
  186. Sleep-dependent structural synaptic plasticity of inhibitory synapses in the dendrites of HYPOCRETIN /OREXIN neurons
  187. Gonadal steroids modulated HYPOCRETIN /OREXIN type-1 receptor expression in a brain region, sex and daytime specific manner
  188. HYPOCRETIN /OREXIN interactions with norepinephrine contribute to the opiate withdrawal syndrome
  189. Neural correlates of arousalโ€induced circadian clock resetting: HYPOCRETIN /OREXIN and the intergeniculate leaflet
  190. Transcriptional regulation of the HYPOCRETIN /OREXIN gene by NR6A1
  191. Cerebrospinal fluid HYPOCRETIN (OREXIN ) levels are elevated by play but are not raised by exercise and its associated heart rate, blood pressure, respiration or โ€ฆ
  192. HYPOCRETIN /OREXIN โ€containing neurons are produced in one sharp peak in the developing ventral diencephalon
  193. Direct inhibition of HYPOCRETIN /OREXIN neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats
  194. โ€ฆ using the smallโ€platformsโ€overโ€water method: polysomnographic analyses and melaninโ€concentrating hormone and HYPOCRETIN /OREXIN neuronal activation before โ€ฆ
  195. Depletion of hypothalamic HYPOCRETIN /OREXIN neurons correlates with impaired memory in a Parkinsonโ€™s disease animal model
  196. HYPOCRETIN /OREXIN peptides alter spike encoding by serotonergic dorsal raphe neurons through two distinct mechanisms that increase the late afterhyperpolarization
  197. Intracellular signal pathways utilized by the HYPOCRETIN /OREXIN receptors
  198. Pleasure, addiction, and HYPOCRETIN (OREXIN )
  199. Activity-dependent release of adenosine inhibits the glutamatergic synaptic transmission and plasticity in the hypothalamic HYPOCRETIN /OREXIN neurons
  200. HYPOCRETIN /OREXIN antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain
  201. Alteration of the expression of the HYPOCRETIN (OREXIN ) gene by 2-deoxyglucose in the rat lateral hypothalamic area
  202. Gender differences between HYPOCRETIN /OREXIN knockout and wild type mice: age, body weight, body composition, metabolic markers, leptin and insulin resistance
  203. Rat HYPOCRETIN /OREXIN neurons are maintained in a depolarized state by TRPC channels
  204. Discovery of HYPOCRETIN /OREXIN ushers in a new era of sleep research
  205. HYPOCRETIN /OREXIN modulates body weight and the metabolism of glucose and insulin
  206. HYPOCRETIN (OREXIN ) and melatonin values in a narcoleptic-like sleep disorder after pinealectomy
  207. Sleep-deprivation regulates ฮฑ-2 adrenergic responses of rat HYPOCRETIN /OREXIN neurons
  208. Effects of HYPOCRETIN (OREXIN ) neuronal loss on sleep and extracellular adenosine levels in the rat basal forebrain
  209. Retraction of the Research Article: โ€œCD4+ T cell autoimmunity to HYPOCRETIN /OREXIN and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsyโ€
  210. Experienceโ€dependent plasticity in HYPOCRETIN /OREXIN neurones: reโ€setting arousal threshold
  211. HYPOCRETIN (OREXIN ) receptor subtypes differentially enhance acetylcholine release and activate g protein subtypes in rat pontine reticular formation
  212. Early expression of HYPOCRETIN /OREXIN in the chick embryo brain
  213. Discharge of identified OREXIN /HYPOCRETIN neurons across the sleep-waking cycle
  214. Increased HYPOCRETIN (OREXIN ) Plasma Level in Depression, Bipolar Disorder Patients
  215. Role of HYPOCRETIN /OREXIN receptor blockade on drug-taking and ultrasonic vocalizations (USVs) associated with low-effort self-administration of cathinone-derived 3, 4 โ€ฆ
  216. Locus coeruleus and tuberomammillary nuclei ablations attenuate HYPOCRETIN /OREXIN antagonist-mediated REM sleep
  217. Role of HYPOCRETIN /OREXIN in the neurobiology of sleep and alertness
  218. Different distributions of preproMCH and HYPOCRETIN /OREXIN in the forebrain of the pig (Sus scrofa domesticus)
  219. HYPOCRETIN (OREXIN ) immunoreactivity in the feline midbrain: Relevance for the generation of wakefulness
  220. Sexually dimorphic and asymmetric effects of embryonic ethanol exposure on HYPOCRETIN /OREXIN neurons as related to behavioral changes in zebrafish
  221. HLA DQB1* 06: 02 negative narcolepsy with HYPOCRETIN /OREXIN deficiency
  222. Role of the HYPOCRETIN (OREXIN ) receptor 2 (Hcrt-r2) in the regulation of HYPOCRETIN level and cataplexy
  223. Slow bursting neurons of mouse cortical layer 6b are depolarized by HYPOCRETIN /OREXIN and major transmitters of arousal
  224. Modulation of Cortical Activity and Sleep-Wake States by HYPOCRETIN /OREXIN
  225. Narcolepsy: selective HYPOCRETIN (OREXIN ) neuronal loss and multiple signaling deficiencies
  226. Morphological and Physiological Interactions Between GnRH3 and HYPOCRETIN /OREXIN Neuronal Systems in Zebrafish (Danio rerio)
  227. Effects of HYPOCRETIN /OREXIN and major transmitters of arousal on fast spiking neurons in mouse cortical layer 6B
  228. Wake-promoting effects of ONO-4127Na, a prostaglandin DP1 receptor antagonist, in HYPOCRETIN /OREXIN deficient narcoleptic mice
  229. HYPOCRETIN /OREXIN loss changes the hypothalamic immune response
  230. Narcolepsy in a HYPOCRETIN /OREXIN โ€deficient chihuahua
  231. Absence of autoreactive CD4+ T-cells targeting HLA-DQA1* 01: 02/DQB1* 06: 02 restricted HYPOCRETIN /OREXIN epitopes in narcolepsy type 1 when detected by EliSpot
  232. OREXIN (HYPOCRETIN ) neurons contain dynorphin
  233. Anti-Tribbles pseudokinase 2 (TRIB2)-immunization modulates HYPOCRETIN /OREXIN neuronal functions
  234. Pre-treatment of blood samples reveal normal blood HYPOCRETIN /OREXIN signal in narcolepsy type 1
  235. HYPOCRETIN (OREXIN ) neuropeptide precursor gene, HCRT, polymorphisms in early-onset narcolepsy with cataplexy
  236. Heterogeneity of HYPOCRETIN /OREXIN Neurons
  237. Cellular Signaling Mechanisms of HYPOCRETIN /OREXIN
  238. The role of HYPOCRETIN /OREXIN in stress-induced analgesia
  239. Transcriptional regulation of the HYPOCRETIN /OREXIN gene
  240. HYPOCRETIN (OREXIN ) pathway to sleep
  241. Changes of HYPOCRETIN (OREXIN ) System in Schizophrenia: From Plasma to Brain
  242. The OREXIN /HYPOCRETIN system: physiology and pathophysiology
  243. HYPOCRETIN /OREXIN prevents recovery from sickness
  244. History and perspectives of HYPOCRETIN /OREXIN research in sleep medicine
  245. HYPOCRETIN /OREXIN antagonists decrease cocaine self-administration by female rhesus monkeys
  246. HYPOCRETIN /OREXIN Receptor Pharmacology and Sleep Phases
  247. Effect of 2-mercaptoacetate and 2-deoxy-D-glucose administration on the expression of NPY, AGRP, POMC, MCH and HYPOCRETIN /OREXIN in the rat hypothalamus
  248. Depletion of HYPOCRETIN /OREXIN neurons increases cell proliferation in the adult subventricular zone
  249. Elevated HBโ€EGF expression in neural stem cells causes middle age obesity by suppressing HYPOCRETIN /OREXIN expression
  250. Plasticity in neurons synthesizing wake/arousal promoting hormone HYPOCRETIN /OREXIN
  251. The emerging role of HYPOCRETIN (OREXIN -a) in the developing central nervous system
  252. Motivational activation: a unifying hypothesis of OREXIN /HYPOCRETIN function
  253. The role of the hypothalamic neuropeptides HYPOCRETIN /OREXIN in the sleep-wake cycle.
  254. Narcolepsy and low CSF OREXIN (HYPOCRETIN ) concentration after a diencephalic stroke
  255. Sleep Problems in Narcolepsy and the Role of HYPOCRETIN /OREXIN Deficiency
  256. HYPOCRETIN /OREXIN , Sleep and Alzheimerโ€™s Disease
  257. HYPOCRETIN (OREXIN ) deficiency in narcolepsy-cataplexy
  258. Overview of OREXIN /HYPOCRETIN system
  259. Normal plasma levels of OREXIN A (HYPOCRETIN -1) in narcoleptic patients
  260. HYPOCRETIN /OREXIN in stress and arousal
  261. Centrally administered OREXIN /HYPOCRETIN activates HPA axis in rats
  262. HYPOCRETIN /OREXIN peptides excite rat neuroendocrine dopamine neurons through OREXIN 2 receptor-mediated activation of a mixed cation current
  263. Selective action of OREXIN (HYPOCRETIN ) on nonspecific thalamocortical projection neurons
  264. Opposing effects of hypoxia on catecholaminergic locus coeruleus and HYPOCRETIN /OREXIN neurons in chick embryos
  265. Age-related loss of OREXIN /HYPOCRETIN neurons
  266. OREXIN (HYPOCRETIN ) receptor agonists and antagonists for treatment of sleep disorders
  267. HYPOCRETIN /OREXIN and motor function
  268. Coordination of metabolism, arousal, and reward by OREXIN /HYPOCRETIN neurons
  269. An investigation of interactions between HYPOCRETIN /OREXIN signaling and glutamate receptor surface expression in the rat nucleus accumbens under basal conditions โ€ฆ
  270. OREXIN /HYPOCRETIN system and autonomic control: new insights and clinical correlations
  271. The OREXIN /HYPOCRETIN system: a critical regulator of neuroendocrine and autonomic function
  272. Recent perspectives on OREXIN /HYPOCRETIN promotion of addiction-related behaviors
  273. Role of OREXIN /HYPOCRETIN in dependence and addiction
  274. OREXIN /HYPOCRETIN excites the histaminergic neurons of the tuberomammillary nucleus
  275. Low levels of ventricular CSF OREXIN /HYPOCRETIN in advanced PD
  276. CSF HYPOCRETIN -1/OREXIN -A concentrations in patients with subarachnoid hemorrhage (SAH)
  277. HYPOCRETIN /OREXIN Replacement Therapy in HYPOCRETIN /OREXIN -Deficient Narcolepsy
  278. Bidirectional and context-dependent changes in theta and gamma oscillatory brain activity in noradrenergic cell-specific HYPOCRETIN /OREXIN receptor 1-KO โ€ฆ
  279. The neural circuit of OREXIN (HYPOCRETIN ): maintaining sleep and wakefulness
  280. Roles of OREXIN /HYPOCRETIN in regulation of sleep/wakefulness and energy homeostasis
  281. Role of the OREXIN /HYPOCRETIN system in stress-related psychiatric disorders
  282. Differential distribution and regulation of OX1 and OX2 OREXIN /HYPOCRETIN receptor messenger RNA in the brain upon fasting
  283. HYPOCRETIN (OREXIN ): what it does and how it links with narcolepsy and food choices
  284. OREXIN /HYPOCRETIN : wired for wakefulness
  285. Effects on sleep and wakefulness of the injection of HYPOCRETIN -1 (OREXIN -A) into the laterodorsal tegmental nucleus of the cat
  286. OREXIN /HYPOCRETIN treatment restores hippocampal-dependent memory in OREXIN -deficient mice
  287. Reactive and predictive homeostasis: roles of OREXIN /HYPOCRETIN neurons
  288. Effects of suvorexant, a dual OREXIN /HYPOCRETIN receptor antagonist, on impulsive behavior associated with cocaine
  289. A decade of OREXIN /HYPOCRETIN and addiction: where are we now?
  290. OREXIN /HYPOCRETIN system modulates amygdala-dependent threat learning through the locus coeruleus
  291. Role of OREXIN /HYPOCRETIN in reward-seeking and addiction: implications for obesity
  292. Roles for OREXIN /HYPOCRETIN in the control of energy balance and metabolism
  293. Pleasure, addiction, and HYPOCRETIN (OREXIN )
  294. The Development of Sleep/Wake Disruption and Cataplexy as HYPOCRETIN /OREXIN Neurons Degenerate in Male vs. Female OREXIN /tTA; TetO-DTA Mice
  295. Physiological characteristics of HYPOCRETIN /OREXIN neurons
  296. Neuronal responses to HYPOCRETIN /OREXIN
  297. Cholinergic Regulation of OREXIN /HYPOCRETIN Neurons Through M3Muscarinic Receptor in Mice
  298. Undetectable levels of CSF HYPOCRETIN -1 (OREXIN -A) in two prepubertal boys with narcolepsy
  299. Changes in OREXIN (HYPOCRETIN ) neuronal expression with normal aging in the human hypothalamus
  300. OREXIN A (HYPOCRETIN -1) application at the medial preoptic area potentiates male sexual behavior in rats
  301. The physiological role of OREXIN /HYPOCRETIN neurons in the regulation of sleep/wakefulness and neuroendocrine functions
  302. Regulation of alcohol-seeking by OREXIN (HYPOCRETIN ) neurons
  303. OREXIN A/HYPOCRETIN -1 selectively promotes motivation for positive reinforcers
  304. Electrical signaling in central OREXIN /HYPOCRETIN circuits: tuning arousal and appetite to fit the environment
  305. Enhanced antinociception by intracerebroventricularly and intrathecally-administered OREXIN A and B (HYPOCRETIN -1 and-2) in mice
  306. Systemic and nasal delivery of OREXIN -A (HYPOCRETIN -1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates
  307. OREXIN /HYPOCRETIN and organizing principles for a diversity of wake-promoting neurons in the brain
  308. OREXIN /HYPOCRETIN neurons: chemical phenotype and possible interactions with melanin-concentrating hormone neurons
  309. HYPOCRETIN (OREXIN ) in Models of Cocaine Addiction
  310. Electrical inhibition of identified anorexigenic POMC neurons by OREXIN /HYPOCRETIN
  311. Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of OREXIN /HYPOCRETIN neurons
  312. The regulation of sleep and wakefulness by the hypothalamic neuropeptide OREXIN /HYPOCRETIN
  313. Effects of OREXIN (HYPOCRETIN ) on GIRK channels
  314. Dopamine-HYPOCRETIN /OREXIN interactions
  315. OREXIN A (HYPOCRETIN 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in rats
  316. The OREXIN /HYPOCRETIN system in zebrafish is connected to the aminergic and cholinergic systems
  317. OREXIN /HYPOCRETIN signaling
  318. OX1 and OX2 OREXIN /HYPOCRETIN receptor pharmacogenetics
  319. Activation of central OREXIN /HYPOCRETIN neurons by dietary amino acids
  320. Symptomatic Narcolepsy or Hypersomnolence with and Without HYPOCRETIN (OREXIN ) Deficiency
  321. Serotonergic regulation of the OREXIN /HYPOCRETIN neurons through the 5-HT1A receptor
  322. OREXIN /HYPOCRETIN : a neuropeptide at the interface of sleep, energy homeostasis, and reward system
  323. OREXIN /HYPOCRETIN modulation of the basal forebrain cholinergic system: role in attention
  324. Distribution of OREXIN /HYPOCRETIN in the rat median eminence and pituitary
  325. OREXIN /HYPOCRETIN modulation of the basal forebrain cholinergic system: insights from in vivo microdialysis studies
  326. HYPOCRETIN -1 (OREXIN -A) levels in human lumbar CSF in different age groups: infants to elderly persons
  327. HYPOCRETIN /OREXIN actions on mesopontine cholinergic systems controling behavioral state
  328. HYPOCRETIN 1/OREXIN A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration
  329. Identification of neurons containing OREXIN -B (HYPOCRETIN -2) immunoreactivity in limbic structures
  330. Role of OREXIN /HYPOCRETIN in conditioned sucrose-seeking in rats
  331. Low cerebrospinal fluid and plasma OREXIN -A (HYPOCRETIN -1) concentrations in combat-related posttraumatic stress disorder
  332. Symptomatic Narcolepsy or Hypersomnia, with and Without HYPOCRETIN (OREXIN ) Deficiency
  333. Ventricular OREXIN -A (HYPOCRETIN -1) levels correlate with rapid-eye-movement sleep without atonia in Parkinsonโ€™s disease
  334. Molecular characterization of HYPOCRETIN /OREXIN and melanin concentrating hormone neurons: relevance to narcolepsy
  335. Diurnal variation of cerebrospinal fluid HYPOCRETIN -1 (OREXIN -A) levels in control and depressed subjects
  336. Decreased cerebrospinal fluid HYPOCRETIN โ€1 (OREXIN A) in patients after repetitive generalized tonicโ€“clonic seizures
  337. Input of OREXIN /HYPOCRETIN neurons revealed by a genetically encoded tracer in mice
  338. Selective excitation of GABAergic neurons in the substantia nigra of the rat by OREXIN /HYPOCRETIN in vitro
  339. From radioimmunoassay to mass spectrometry: a new method to quantify OREXIN -A (HYPOCRETIN -1) in cerebrospinal fluid
  340. Increased HYPOCRETIN -1 (OREXIN -a) levels in cerebrospinal fluid of rats after short-term forced activity
  341. The role of OREXIN /HYPOCRETIN in the central nervous system and peripheral tissues
  342. Increased and decreased muscle tone with OREXIN (HYPOCRETIN ) microinjections in the locus coeruleus and pontine inhibitory area
  343. Editorial [Hot Topic: The Sleep-Wake Cycle, the HYPOCRETIN /OREXIN System and Narcolepsy: Advances from Preclinical Research to Treatment (Guest Editors: Oscar โ€ฆ
  344. Convergent actions of OREXIN /HYPOCRETIN and CRF on dopamine neurons: emerging players in addiction
  345. CSF levels of HYPOCRETIN -1 (OREXIN -A) peak during early infancy in humans
  346. Diurnal regulation of the OREXIN /HYPOCRETIN system in mice
  347. OREXIN /HYPOCRETIN system: role in food and drug overconsumption
  348. Role of the OREXIN (HYPOCRETIN ) system in contextual fear conditioning in rats
  349. The narcoleptic borderland: a multimodal diagnostic approach including cerebrospinal fluid levels of HYPOCRETIN -1 (OREXIN A)
  350. The histaminergic system regulates wakefulness and OREXIN /HYPOCRETIN neuron development via histamine receptor H1 in zebrafish
  351. OREXIN (HYPOCRETIN ) innervation of the paraventricular nucleus of the thalamus
  352. Multiple roles for OREXIN /HYPOCRETIN in addiction
  353. The highly selective OREXIN /HYPOCRETIN 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice
  354. OREXIN /HYPOCRETIN based pharmacotherapies for the treatment of addiction: DORA or SORA?
  355. OREXIN /HYPOCRETIN receptor, Orx1, gene variants are associated with major depressive disorder
  356. The dual role of the OREXIN /HYPOCRETIN system in modulating wakefulness and respiratory drive
  357. HYPOCRETIN -1 (OREXIN A) deficiency in acute traumatic brain injury
  358. Do OREXIN /HYPOCRETIN neurons signal stress or reward?
  359. Depressive behavior and activation of the OREXIN /HYPOCRETIN system.
  360. Biomedical application of OREXIN /HYPOCRETIN receptor ligands in neuroscience
  361. Lateral hypothalamic OREXIN /HYPOCRETIN neurons: a role in reward-seeking and addiction
  362. Cerebrospinal fluid HYPOCRETIN -1 (OREXIN -A) level fluctuates with season and correlates with day length
  363. The integrative role of OREXIN /HYPOCRETIN neurons in nociceptive perception and analgesic regulation
  364. Revealing the potential of intranasally administered OREXIN A (HYPOCRETIN -1)
  365. Autoimmunity to HYPOCRETIN /OREXIN and Molecular Mimicry to Flu in Type 1 Narcolepsy (4989)
  366. HYPOCRETIN (OREXIN ) pathology in Alzheimerโ€™s disease
  367. Decreased HYPOCRETIN -1 (OREXIN -A) levels in the cerebrospinal fluid of patients with myotonic dystrophy and excessive daytime sleepiness
  368. OREXIN /HYPOCRETIN receptor chimaeras reveal structural features important for OREXIN peptide distinction
  369. Normal CSF HYPOCRETIN -1 (OREXIN A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness
  370. HYPOCRETIN /OREXIN tonus and vigilance control
  371. OREXIN /HYPOCRETIN and dysregulated eating: Promotion of foraging behavior
  372. Cholecystokinin activates OREXIN /HYPOCRETIN neurons through the cholecystokinin A receptor
  373. Changes in CSF HYPOCRETIN -1 (OREXIN A) levels in rats across 24 hours and in response to food deprivation
  374. Normal HYPOCRETIN -1 (OREXIN -A) levels in the cerebrospinal fluid of patients with Huntingtonโ€™s disease
  375. CSF OREXIN -A/HYPOCRETIN -1 concentrations in patients with intracerebral hemorrhage (ICH)
  376. Long-lasting silencing of OREXIN /HYPOCRETIN neurons using archaerhodopsin induces slow-wave sleep in mice
  377. OREXIN /HYPOCRETIN (Orx/Hcrt) transmission and drug-seeking behavior: is the paraventricular nucleus of the thalamus (PVT) part of the drug seeking circuitry?
  378. Circadian and dark-pulse activation of OREXIN /HYPOCRETIN neurons
  379. OREXIN -A (HYPOCRETIN -1) is possibly involved in generation of anxiety-like behavior
  380. Functional roles of OREXIN /HYPOCRETIN receptors in reward circuit
  381. A case with HYPOCRETIN (OREXIN ) deficient narcolepsy, Parkinsonโ€™s disease and severe psychosis was successfully treated by modified electro-convulsive therapy
  382. Activation of OREXIN /HYPOCRETIN projections to basal forebrain and paraventricular thalamus by acute nicotine
  383. Interactions of the OREXIN /HYPOCRETIN neurones and the histaminergic system
  384. OREXIN (HYPOCRETIN )-like immunoreactivity in the cat hypothalamus: a light and electron microscopic study
  385. HYPOCRETIN (OREXIN ) Cell Transplantation as a New Therapeutic Approach in Narcolepsy
  386. Altered allostatic regulation of wakefulness and slow-wave-sleep spectral quality in mice with HYPOCRETIN (OREXIN ) receptor 1 inactivation in noradrenergic cells
  387. Interactions of neuropeptide Y, HYPOCRETIN -I (OREXIN A) and melanin-concentrating hormone on feeding in rats
  388. OREXIN /HYPOCRETIN receptor gene (HCRTR1) variation is associated with aggressive behaviour
  389. Hypersomnia and low CSF HYPOCRETIN -1 (OREXIN -A) concentration in a patient with multiple sclerosis showing bilateral hypothalamic lesions
  390. An investigation of the role of the neuropeptide HYPOCRETIN /OREXIN in stress
  391. Increased number of OREXIN /HYPOCRETIN neurons with high and prolonged external stress-induced depression
  392. Postnatal development of OREXIN /HYPOCRETIN in rats
  393. Optical probing of OREXIN /HYPOCRETIN receptor antagonists
  394. Immunohistochemical localization of OREXIN /HYPOCRETIN -like immunoreactive peptides and melanin-concentrating hormone in the brain and pituitary of medaka
  395. Mu-opioid stimulation in rat prefrontal cortex engages hypothalamic OREXIN /HYPOCRETIN -containing neurons, and reveals dissociable roles of nucleus accumbens and โ€ฆ
  396. Symptomatic Narcolepsy with Cataplexy and Without Cataplexy or Hypersomnia, with and Without HYPOCRETIN (OREXIN ) Deficiency
  397. Paradoxical function of OREXIN /HYPOCRETIN circuits in a mouse model of Huntingtonโ€™s disease
  398. OREXIN /HYPOCRETIN and histamine: distinct roles in the control of wakefulness demonstrated using knock-out mouse models
  399. Olfactory dysfunction in patients with narcolepsy with cataplexy is restored by intranasal OREXIN A (HYPOCRETIN -1)
  400. Hormonal Abnormalities in HYPOCRETIN /OREXIN Deficient Human Narcolepsy
  401. HYPOCRETIN /OREXIN Pathology in Human Narcolepsy with and Without Cataplexy
  402. The HYPOCRETIN /OREXIN System and Fear Learning
  403. Lateral hypothalamic OREXIN /HYPOCRETIN neurons that project to ventral tegmental area are differentially activated with morphine preference
  404. HYPOCRETIN /OREXIN Receptor Functions in Mesopontine Systems Regulating Sleep, Arousal, and Cataplexy
  405. Acute optogenetic silencing of OREXIN /HYPOCRETIN neurons induces slow-wave sleep in mice
  406. Muscle tone facilitation and inhibition after OREXIN -a (HYPOCRETIN -1) microinjections into the medial medulla
  407. Pressor response to microinjection of OREXIN /HYPOCRETIN into rostral ventrolateral medulla of awake rats
  408. Association of OREXIN /HYPOCRETIN receptor gene (HCRTR1) with reward sensitivity, and interaction with gender
  409. A mathematical model of sleep-wake cycles: the role of HYPOCRETIN /OREXIN in homeostatic regulation and thalamic synchronization
  410. Electrophysiological effects of OREXIN /HYPOCRETIN on nucleus accumbens shell neurons in rats: an in vitro study
  411. โ€ฆ of Putative Appositions from Neurons Expressing Alpha-Melanocyte-Stimulating Hormone with Neurons Expressing HYPOCRETIN /OREXIN or Melanin-Concentrating โ€ฆ
  412. OREXIN (HYPOCRETIN ) and addiction
  413. The effect of intranasal OREXIN -A (HYPOCRETIN -1) on sleep, wakefulness and attention in narcolepsy with cataplexy
  414. Recent progress in OREXIN /HYPOCRETIN physiology and pharmacology
  415. Relationship between cerebrospinal fluid concentrations of OREXIN A/HYPOCRETIN -1 and body composition in humans
  416. Vasopressin increases locomotion through a V1a receptor in OREXIN /HYPOCRETIN neurons: implications for water homeostasis
  417. Increased CSF HYPOCRETIN -1 (OREXIN -A) in restless legs syndrome
  418. Conditional ablation of OREXIN /HYPOCRETIN neurons: a new mouse model for the study of narcolepsy and OREXIN system function
  419. The electrical activity of hippocampal pyramidal neuron is subjected to descending control by the brain OREXIN /HYPOCRETIN system
  420. Dysregulation of the OREXIN /HYPOCRETIN system is not limited to narcolepsy but has farโ€reaching implications for neurological disorders
  421. OREXIN /HYPOCRETIN plays a role in the response to physiological disequilibrium
  422. Decreased CSF HYPOCRETIN -1 (OREXIN -A) after acute haemorrhagic brain injury
  423. OREXIN /HYPOCRETIN is necessary for context-driven cocaine-seeking
  424. OREXIN /HYPOCRETIN and MCH Neurons: Cognitive and Motor Roles Beyond Arousal
  425. Functional opioid pathways are necessary for HYPOCRETIN -1 (OREXIN -A)-induced feeding
  426. The OREXIN /HYPOCRETIN system in neuropsychiatric disorders: Relation to signs and symptoms
  427. OREXIN /HYPOCRETIN -1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats
  428. Attenuation of saccharin-seeking in rats by OREXIN /HYPOCRETIN receptor 1 antagonist
  429. The OREXIN (HYPOCRETIN ) neuropeptide system is a target for novel therapeutics to treat cocaine use disorder with alcohol coabuse
  430. Pharmacological and chemogenetic OREXIN /HYPOCRETIN intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinsonโ€™s โ€ฆ
  431. OREXIN /HYPOCRETIN modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences
  432. An Approach to Determining the Functions of HYPOCRETIN (OREXIN )
  433. Comment on โ€œCD4+ T Cell Autoimmunity to HYPOCRETIN /OREXIN and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsyโ€
  434. Stimulant doses of caffeine induce c-FOS activation in OREXIN /HYPOCRETIN -containing neurons in rat
  435. CSF HYPOCRETIN -1 (OREXIN -A) levels in childhood narcolepsy and neurologic disorders
  436. Reduction of Plasma Leptin Levels and Loss of Its Circadian Rhythmicity in HYPOCRETIN (OREXIN )-Deficient Narcolepticโ€ฆ
  437. Selective Fos induction in hypothalamic OREXIN /HYPOCRETIN , but not melanin-concentrating hormone neurons, by a learned food-cue that stimulates feeding in sated rats
  438. HYPOCRETIN /OREXIN System
  439. Aging-related alterations in OREXIN /HYPOCRETIN modulation of septo-hippocampal amino acid neurotransmission
  440. HYPOCRETIN /OREXIN receptor 1-KO mice
  441. OREXIN -A (HYPOCRETIN -1) and leptin enhance LTP in the dentate gyrus of rats in vivo
  442. Ectopic expression of melanopsin in OREXIN /HYPOCRETIN neurons enables control of wakefulness of mice in vivo by blue light
  443. Narcolepsy without cataplexy: 2 subtypes based on CSF HYPOCRETIN -1/OREXIN -A findings
  444. Inhibition of OREXIN -1/HYPOCRETIN -1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Longโ€“Evans rats
  445. Normal Role of HYPOCRETIN /OREXIN
  446. Convergent excitation of dorsal raphe serotonin neurons by multiple arousal systems (OREXIN /HYPOCRETIN , histamine and noradrenaline)
  447. OX1 OREXIN /HYPOCRETIN receptor signaling through arachidonic acid and endocannabinoid release
  448. Cerebrospinal fluid HYPOCRETIN -1 (OREXIN A) levels in mania compared to unipolar depression and healthy controls
  449. OREXIN /HYPOCRETIN -1 receptor antagonism selectively reduces cue-induced feeding in sated rats and recruits medial prefrontal cortex and thalamus
  450. OREXIN (HYPOCRETIN ) Effects on Constitutively Active Inward Rectifier K+ Channels in Cultured Nucleus Basalis Neurons
  451. CD4+ T-Cell Reactivity to OREXIN /HYPOCRETIN in Patients With Narcolepsy Type 1
  452. Increased number and activity of a lateral subpopulation of hypothalamic OREXIN /HYPOCRETIN neurons underlies the expression of an addicted state in rats
  453. Activation of OREXIN /HYPOCRETIN neurons is associated with individual differences in cued fear extinction
  454. Relationship of OREXIN (HYPOCRETIN ) system and astrocyte activation in Parkinsonโ€™s disease with hypersomnolence
  455. The excitatory/inhibitory input to OREXIN /HYPOCRETIN neuron soma undergoes day/night reorganization
  456. Normal cerebrospinal fluid levels of HYPOCRETIN -1 (OREXIN A) in patients with fibromyalgia syndrome
  457. Lipid signaling cascades of OREXIN /HYPOCRETIN receptors
  458. The dual OREXIN /HYPOCRETIN receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration
  459. Cerebrospinal fluid melanin-concentrating hormone (MCH) and HYPOCRETIN -1 (HCRT-1, OREXIN -A) in Alzheimerโ€™s disease
  460. Effects of IV and ICV HYPOCRETIN -1 (OREXIN A) in HYPOCRETIN receptor-2 gene mutated narcoleptic dogs and IV HYPOCRETIN -1 replacement therapy in a HYPOCRETIN -ligand โ€ฆ
  461. Distribution of OREXIN /HYPOCRETIN immunoreactivity in the nervous system of the green Treefrog, Hyla cinerea
  462. Dichotomous cellular properties of mouse OREXIN /HYPOCRETIN neurons
  463. Pretreatment with subeffective doses of Rimonabant attenuates orexigenic actions of OREXIN A-HYPOCRETIN 1
  464. HYPOCRETIN /OREXIN Tonus and Vigilance Control
  465. Direct and indirect control of OREXIN /HYPOCRETIN neurons by glycine receptors
  466. Metabolic Influence on the HYPOCRETIN /OREXIN Neurons
  467. Behavioral neuroscience of OREXIN /HYPOCRETIN
  468. HYPOCRETIN /OREXIN and Sleep
  469. OREXIN or HYPOCRETIN ?
  470. Both corticotropin releasing factor and neuropeptide Y are involved in the effect of OREXIN (HYPOCRETIN ) on the food intake in rats
  471. Expression of OREXIN -A (HYPOCRETIN -A) in the hypothalamus after traumatic brain injury: A postmortem evaluation
  472. Increased numbers of OREXIN /HYPOCRETIN neurons in a genetic rat depression model
  473. Intranasal drug targeting of HYPOCRETIN -1 (OREXIN -A) to the central nervous system
  474. Potential Mechanisms of the Wake-Promoting Action of HYPOCRETIN /OREXIN
  475. Chemogenetic activation of OREXIN /HYPOCRETIN neurons ameliorates aging-induced changes in behavior and energy expenditure
  476. Role of OREXIN /HYPOCRETIN and CRF in the formation of drug-dependent synaptic plasticity in the mesolimbic system
  477. Excitatory effects of HYPOCRETIN -1 (OREXIN -A) in the trigeminal motor nucleus are reversed by NMDA antagonism
  478. OREXIN A (HYPOCRETIN -1) levels are not reduced while cocaine/amphetamine regulated transcript levels are increased in the cerebrospinal fluid of patients with multiple โ€ฆ
  479. Effects of intranasal OREXIN -A (HYPOCRETIN -1) administration on neuronal activation, neurochemistry, and attention in aged rats
  480. Afferent Control of the HYPOCRETIN /OREXIN Neurons
  481. Effects of changes in energy homeostasis and exposure of noxious insults on the expression of OREXIN (HYPOCRETIN ) and its receptors in the brain
  482. Abstract# 3107 A role for HYPOCRETIN /OREXIN in metabolic and sleep abnormalities in a mouse model of non-metastatic breast cancer
  483. Involvement of the HYPOCRETIN /OREXIN system in the addictive properties of nicotine
  484. Pharmacology of HYPOCRETIN /OREXIN Peptides and Small Molecules
  485. Stimulation of OREXIN /HYPOCRETIN neurones by thyrotropinโ€releasing hormone
  486. OREXIN /HYPOCRETIN receptor modulation of anxiolytic and antidepressive responses during social stress and decision-making: potential for therapy
  487. Leptin Receptorโ€ and STAT3โ€Immunoreactivities in HYPOCRETIN /OREXIN Neurones of the Lateral Hypothalamus1
  488. Neuroanatomical relationships between OREXIN /HYPOCRETIN -containing neurons/nerve fibers and nicotine-induced c-Fos-activated cells of the reward-addiction โ€ฆ
  489. Effect of a HYPOCRETIN /OREXIN Antagonist on Neurocognitive Performance
  490. HYPOCRETIN /OREXIN and the Ventral Midbrain: Topography and Function Associated with Psychostimulant-taking and Affect
  491. OREXIN /HYPOCRETIN levels in the cerebrospinal fluid and characteristics of patients with myotonic dystrophy type 1 with excessive daytime sleepiness
  492. The HYPOCRETIN /OREXIN system mediates the extinction of fear memories
  493. OREXIN /HYPOCRETIN system: obesity, narcolepsy and beyond
  494. Effect of a HYPOCRETIN /OREXIN Antagonist on Neurocognitive Performance
  495. Narcolepsy: a neurodegenerative disease of the HYPOCRETIN /OREXIN system?
  496. Identification and functional analysis of mutation in the HYPOCRETIN (OREXIN ) genes of narcoleptic canines.
  497. The level of HYPOCRETIN 1 (OREXIN A) in cerebrospinal fluid and the diagnosis of narcolepsy and other somnolent disorders
  498. Molecular mechanism of tumor necrosis factor alpha regulates HYPOCRETIN (OREXIN ) system, sleep, and behavior in mice
  499. Modulation of respiratory activity by HYPOCRETIN -1 (OREXIN A) in situ and in vitro
  500. Pharmacological characterization of the OREXIN /HYPOCRETIN receptor agonist Nag 26
  501. Role of OREXIN /HYPOCRETIN in conditioned sucrose-seeking in female rats
  502. Distribution of OREXIN /HYPOCRETIN immunoreactivity in the brain of a male songbird, the house finch, Carpodacus mexicanus
  503. OREXIN -A (HYPOCRETIN 1)-like immunoreactivity in growth hormone-containing cells of the Japanese seaperch (Lateolabrax japonicus) pituitary
  504. Central OREXIN (HYPOCRETIN ) 2 receptor antagonism reduces ethanol self-administration, but not cue-conditioned ethanol-seeking, in ethanol-preferring rats
  505. The HYPOCRETIN /OREXIN receptor-1 as a novel target to modulate cannabinoid reward
  506. HYPOCRETIN -1 (OREXIN A) levels are normal in Huntingtonโ€™s disease
  507. The Roles of HYPOCRETIN /OREXIN in Narcolepsy, Parkinsonโ€™s Disease, and Normal Behavior
  508. Upregulation of OREXIN /HYPOCRETIN expression in aged rats: Effects on feeding latency and neurotransmission in the insular cortex
  509. HYPOCRETIN (OREXIN ), dopamine, and goal-directed behavior
  510. Effects Of HYPOCRETIN /OREXIN on the Thalamocortical Activating System
  511. HYPOCRETIN (OREXIN ) and melanin concentrating hormone loss and the symptoms of Parkinsonโ€™s
  512. Narcolepsy-The role of HYPOCRETIN /OREXIN in the sleep-wake cycle
  513. Sleep/wake disorders and the HYPOCRETIN /OREXIN system in a zebrafish model of Parkinsonโ€™s Disease
  514. Integration and output of HYPOCRETIN /OREXIN neurons and the dynamics of sleep-to-wake transitions
  515. Anxiolytic function of the OREXIN 2/HYPOCRETIN A receptor in the basolateral amygdala
  516. HYPOCRETIN /OREXIN B potentiates the excitatory synaptic transmission to OREXIN -sensitive neurons in layer 6b of mouse visual cortex
  517. Hypothalamic cocaine-and amphetamine-regulated transcript (CART) neurons: histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating โ€ฆ
  518. Chatper 32. Normal Role of HYPOCRETIN /OREXIN
  519. Organization of the OREXIN /HYPOCRETIN system in the brain of two basal actinopterygian fishes, the cladistians Polypterus senegalus and Erpetoichthys calabaricus
  520. Retracted: HYPOCRETIN (OREXIN ) cell transplantation diminishes narcoleptic-like sleep behavior in rats.
  521. Knockdown of HYPOCRETIN /OREXIN Attenuates Extended-Access Cocaine Self-Administration in Rats
  522. Sleep dysregulation in binge eating disorder and โ€œfood addictionโ€: the OREXIN (HYPOCRETIN ) system as a potential neurobiological link
  523. Regulation by HYPOCRETIN (OREXIN ) of excitatory postsynaptic potentials in layer V pyramidal neurons of murine prefrontal cortex
  524. 2 HYPOCRETIN (OREXIN ) Loss in Parkinsonโ€™s Disease
  525. The paraventricular nucleus of the thalamus is recruited by both natural rewards and drugs of abuse: recent evidence of a pivotal role for OREXIN /HYPOCRETIN โ€ฆ
  526. Retrograde study of HYPOCRETIN -1 (OREXIN -A) projections to subdivisions of the dorsal raphe nucleus in the rat
  527. History and overview of OREXIN /HYPOCRETIN research
  528. The anti-tumoral properties of OREXIN /HYPOCRETIN hypothalamic neuropeptides: an unexpected therapeutic role
  529. Reduction in Bladder Volume Alters Expression of HYPOCRETIN /OREXIN Receptors in Brain Stem in Rats: a Correlation With Sleep Architecture
  530. Hypothalamic neurons expressing HYPOCRETIN /OREXIN peptides are necessary for the physiological effects of sleep on blood pressure
  531. CHRONIC OREXIN -A (HYPOCRETIN -1) TREATMENT OF TYPE 2 DIABETIC RATS IMPROVES GLUCOSE CONTROL AND ฮ’ฮ•ฮคฮ‘-CELL FUNCTIONS
  532. Diminished feeding responsiveness to OREXIN A (HYPOCRETIN 1) in aged rats is accompanied by decreased neuronal activation
  533. Distribution of OREXIN /HYPOCRETIN immunoreactivity in the brain of the lungfishes Protopterus dolloi and Neoceratodus forsteri
  534. Mapping of the binding sites for the OX1 OREXIN receptor antagonist, SB-334867, using OREXIN /HYPOCRETIN receptor chimaeras
  535. HYPOCRETIN (OREXIN ) Regulates Glutamate Input to Fast-Spiking Interneurons in Layer V of the Fr2 Region of the Mโ€ฆ
  536. A ventral striatal-OREXIN /HYPOCRETIN circuit modulates approach but not consumption of food
  537. Retraction of the Letter:โ€œComment on โ€˜CD4+ T cell autoimmunity to HYPOCRETIN /OREXIN and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsyโ€™โ€
  538. Inhibition of OREXIN /HYPOCRETIN Neurons Ameliorates Elevated Physical Activity and Energy Expenditure in the A53T Mouse Model of Parkinsonโ€™s Disease
  539. The OREXIN /HYPOCRETIN System and Stress and Emotion
  540. Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and โ€ฆ
  541. Distribution of hypothalamic neurons with OREXIN (HYPOCRETIN ) or melanin concentrating hormone (MCH) immunoreactivity and multisynaptic connections with โ€ฆ
  542. Retraction of the Research Article:โ€ CD4+ T cell autoimmunity to HYPOCRETIN /OREXIN and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsyโ€
  543. Organization of the OREXIN /HYPOCRETIN system in the brain of holostean fishes: assessment of possible relationships with monoamines and neuropeptide Y
  544. Dietary therapy restores glutamatergic input to OREXIN /HYPOCRETIN neurons after traumatic brain injury in mice
  545. Novel pathways for stimulant development 11: the HYPOCRETIN /OREXIN
  546. Influence of inhibitory serotonergic inputs to OREXIN /HYPOCRETIN neurons on the diurnal rhythm of sleep and wakefulness
  547. Erratum: CD4+ T Cell Autoimmunity to HYPOCRETIN /OREXIN and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsy (Science Translational Medicine โ€ฆ
  548. Optogenetic activation of serotonergic terminals facilitates GABAergic inhibitory input to OREXIN /HYPOCRETIN neurons
  549. Age-specific treatment effects of OREXIN /HYPOCRETIN -receptor antagonism on methamphetamine-seeking behavior
  550. OREXIN -A/HYPOCRETIN -1 mediates cocaine-seeking behavior in the posterior paraventricular nucleus of the thalamus via OREXIN /HYPOCRETIN receptor-2
  551. Effects of intranasal HYPOCRETIN -1 (OREXIN A) on sleep in narcolepsy with cataplexy
  552. Modulatory effects of HYPOCRETIN -1/OREXIN -A with glutamate and ฮณ-aminobutyric acid on freshly isolated pyramidal neurons from the rat prefrontal cortex
  553. A mathematical model to explore the interdependence between the serotonin and OREXIN /HYPOCRETIN systems
  554. OREXIN /HYPOCRETIN Type 2 Receptor (HCRTR2) Gene as a Candidate Gene in Sertraline-Associated Insomnia in Depressed Patients
  555. Involvement of OREXIN /HYPOCRETIN in the expression of social play behaviour in juvenile rats
  556. G. 1-THE HYPOCRETIN /OREXIN RECEPTOR-1 AS A NOVEL TARGET TO MODULATE CANNABINOID REWARD
  557. The number of lateral hypothalamus OREXIN /HYPOCRETIN neurons contributes to individual differences in cocaine demand
  558. The human OREXIN /HYPOCRETIN receptor crystal structures
  559. Hypothalamic OREXIN -A (HYPOCRETIN -1) neuronal projections to the vestibular complex and cerebellum in the rat
  560. OREXIN (HYPOCRETIN ) and narcolepsy
  561. Adolescent alcohol exposure increases OREXIN -A/HYPOCRETIN -1 in the anterior hypothalamus
  562. OREXIN -A (HYPOCRETIN -1) impairs Morris water maze performance and CA1-Schaffer collateral long-term potentiation in rats
  563. Genomic organization and regulation of the human OREXIN (HYPOCRETIN ) receptor 2 gene: identification of alternative promoters
  564. OREXIN (HYPOCRETIN ) participates in central autonomic regulation during fight-or-flight response
  565. IP3-independent signalling of OX1 OREXIN /HYPOCRETIN receptors to Ca2+ influx and ERK
  566. Pharmacology of OREXIN /HYPOCRETIN receptors
  567. OREXIN -A/HYPOCRETIN -1 Controls the VTA-NAc Mesolimbic Pathway via Endocannabinoid-Mediated Disinhibition of Dopaminergic Neurons in Obese Mice
  568. Nicotinic receptor blockade decreases fos immunoreactivity within OREXIN /HYPOCRETIN -expressing neurons of nicotine-exposed rats
  569. OREXIN receptor agonist Yan 7874 is a weak agonist of OREXIN /HYPOCRETIN receptors and shows OREXIN receptor-independent cytotoxicity
  570. Activation of lateral hypothalamic group III metabotropic glutamate receptors suppresses cocaine-seeking following abstinence and normalizes drug-associated โ€ฆ
  571. HYPOCRETIN -1 (OREXIN A) prevents the effects of hypoxia/hypercapnia and enhances the GABAergic pathway from the lateral paragigantocellular nucleus to cardiac โ€ฆ
  572. A patient with anti-aquaporin 4 antibody who presented with recurrent hypersomnia, reduced OREXIN (HYPOCRETIN ) level, and symmetrical hypothalamic lesions
  573. Cytosolic calcium elevation induced by OREXIN /HYPOCRETIN in granule cell domain cells of the rat cochlear nucleus in vitro
  574. Role of lateral hypothalamic OREXIN (HYPOCRETIN ) neurons in alcohol use and abuse: recent advances
  575. The OREXIN /HYPOCRETIN System: Functional Roles and Therapeutic Potential
  576. In Vivo Pharmacology of OREXIN (HYPOCRETIN ) Receptors
  577. OREXIN -A/HYPOCRETIN -1 immunoreactivity in the lateral hypothalamus is reduced in genetically obese but not in diet-induced obese mice
  578. Effects of OREXIN /HYPOCRETIN on Ventral Tegmental Area Dopamine Neurons: An Emerging Role in Addiction
  579. Effects of cocaine place conditioning, chronic escalating-dose โ€œbingeโ€ pattern cocaine administration and acute withdrawal on OREXIN /HYPOCRETIN and preprodynorphin โ€ฆ
  580. The Prehistory of OREXIN /HYPOCRETIN and Melanin-Concentrating Hormone Neurons of the Lateral
  581. Normal HYPOCRETIN -1 (OREXIN A) levels in cerebrospinal fluid in patients with idiopathic intracranial hypertension
  582. OREXIN /HYPOCRETIN Antagonists in Insomnia: From Bench to Clinic
  583. Activation of lateral hypothalamic group III mGluRs suppresses drug-seeking following abstinence and cocaine-associated increases in excitatory drive to OREXIN โ€ฆ
  584. Symptomatic Narcolepsy or Hypersomnia, with and Without OREXIN (HYPOCRETIN ) Deficiency
  585. OREXIN /HYPOCRETIN and Histamine: Distinct Roles in the Control of Wakefulness Demonstrated Using Knock-Out Mouse Models
  586. Involvement of the OREXIN /HYPOCRETIN system in ethanol-conditioned behavior
  587. The underlying mechanisms of the OREXIN (HYPOCRETIN ) system in anxiety and fear
  588. Selective loss of GABAB receptors in OREXIN /HYPOCRETIN -producing neurons results in disrupted sleep/wakefulness architecture
  589. OREXIN /HYPOCRETIN and Opioid Dependence
  590. Investigations into the Role of OREXIN (HYPOCRETIN ) and Dynorphin in Drug Seeking, Reinforcement, and Withdrawal
  591. Developmental changes in CSF HYPOCRETIN โ€1 (OREXIN โ€A) levels in normal and genetically narcoleptic Doberman pinschers
  592. Input and Output of OREXIN /HYPOCRETIN Neurons: Link Between Arousal Pathways and Feeding Behavior
  593. The orexigenic effect of HYPOCRETIN -1 (OREXIN -A) in the lateral hypothalamus
  594. Interaction of OREXIN /HYPOCRETIN -like immunoreactive neurons with melanin-concentrating hormone and ฮฑ-melanocyte-stimulating hormone neurons in brain of a โ€ฆ
  595. CSF HYPOCRETIN -1/OREXIN -A in narcolepsy: technical aspects and clinical experience in the United States
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Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

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