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Hallmarks Of Aging

  1. Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice
  2. AGING of Immune System
  3. Sex-specific components of frailty in C57BL/6 mice
  4. Long live the queen, the king and the commoner? Transcript expression differences between old and young in the termite Cryptotermes secundus
  5. Ten years of brainage as a neuroimAGING biomarker of brain AGING: what insights have we gained?
  6. In vitro model of chronological AGING of adipocytes: interrelationships with hypoxia and oxidation
  7. Gastrointestinal tract disorders in older age
  8. Frailty biomarkers in humans and rodents: current approaches and future advances
  9. Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
  10. Peripheral antibody concentrations are associated with highly differentiated T cells and inflammatory processes in the human bone marrow
  11. LncRNA GASL1 inhibits growth and promotes expression of apoptosis‑associated proteins in prostate carcinoma cells through GLUT‑1
  12. SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy
  13. Adult cardiac stem cell AGING: a reversible stochastic phenomenon?
  14. The mTORC1-autophagy pathway is a target for senescent cell elimination
  15. Harvard HIV and AGING workshop: perspectives and priorities from Claude D. Pepper Centers and Centers for AIDS Research
  16. Oxidative stress resistance as a factor in AGING: evidence from an extended longevity phenotype of Drosophila melanogaster
  17. Gene-environment interaction and Mendelian randomisation
  18. Natural bioactive compounds as protectors of mitochondrial dysfunction in cardiovascular diseases and AGING
  19. Adipose-derived mesenchymal stem cells isolated from patients with abdominal aortic aneurysm exhibit senescence phenomena
  20. Age-associated epigenetic modifications in human DNA increase its immunogenicity
  21. AGING in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase‐67 positive interneurons but not interneuron …
  22. Effects Sulforaphane on IMR‐90 Phase II Enzyme Induction and Cell Senescence
  23. www. impactAGING. com AGING, July 2013, Vol. 5 No 7
  24. P 132. Modulation of encoding-related networks by intermittent TBS stimulation in healthy AGING
  25. A Means to an End: The Biological Basis of AGING and Death
  26. Accelerated AGING in Down’s Syndrome: The Concept of Hierarchical Homeostasis in Relation to Local and Global Failure
  27. Crosstalk between oxidative stress and SIRT1: impact on the AGING process
  28. Understanding the Relations among Episodic Memory, Associative Learning, and Fluid Intelligence in Younger and Older Adults
  29. Electrophysiology and AGING: slowing, inhibition, and aerobic fitness
  30. AGING-like circadian disturbances in folate-deficient mice
  31. Influence of controlled dietary restriction on immunologic function and AGING.
  32. Identifying Morphological and Functional Changes in a Caenorhabditis elegans Neuronal AGING Model of Huntington’s Disease
  33. Oxidative damage in rat brain during AGING: interplay between energy and metabolic key target proteins
  34. Metabolism of cholesterol in health and disease of the retina
  35. AGING-associated decline in innate immunity and therapeutic strategies to counteract it
  36. Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelial function in patients with isolated systolic hypertension
  37. Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study
  38. AGING, cellular senescence, and cancer
  39. Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA
  40. The quest to extend life and overcome AGING and death: past, present, and future attempts
  41. AGING-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation
  42. AGING Induces Titin Oxidation And Increases Passive Cardiomyocyte Stiffness
  43. Age‐specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro
  44. Evidence for loss of myelinated input to the spinal cord in senescent rats
  45. Molecular pathology of AGING and its implications for senescent coronary atherosclerosis
  46. Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T‐cell AGING
  47. 22 Hyaluronan and the Process of AGING in Skin
  48. Injection techniques for revolumization of the perioral region with hyaluronic acid
  49. Elastin peptides in AGING and pathological conditions
  50. Omega‐3 fatty acids deficiency aggravates glutamatergic synapse and astroglial AGING in the rat hippocampal CA 1
  51. The AGING endoplasmic reticulum
  52. Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the AGING process
  53. Molecular bases of progeroid syndromes
  54. The effects of AGING and training on skeletal muscle
  55. Sarcopenia in older people
  56. The senescent primate brain
  57. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat)
  58. Multifaceted AGING and rapamycin
  59. Emerging role of sirtuins on tumorigenesis: possible link between AGING and cancer
  60. Cognitive function, AGING, and ethical decisions: recognizing change
  61. Roy L. Walford, Faramarz Naeim, Kathleen Y. Hall
  62. “The Molecular Basis of AGING”: The Boehringer Ingelheim Fonds 95th International Titisee Conference
  63. Frailty and chronic diseases in older adults
  64. Mitochondrial gene mutation: the ageing process and degenerative diseases.
  65. Decline in self-renewal factors contributes to AGING of the stem cell niche in the Drosophila testis
  66. Artery changes with AGING: degeneration or adaptation
  67. The AGING striatal dopamine function
  68. Reactive oxygen species: relation to AGING and neurotoxic damage.
  69. Investigation of potential cognitive tests for use with older adults in audiology clinics
  70. Age-related patterns of body composition and salivary testosterone among Ariaal men of Northern Kenya
  71. Age-related changes in the hippocampus (loss of synaptophysin and glial–synaptic interaction) are modified by systemic treatment with an NCAM-derived peptide …
  72. New Cells in Old Mice: The ABCs of Humoral Immunosenescence
  73. Structure and function of the thymic microenvironment
  74. Sestrins orchestrate cellular metabolism to attenuate AGING
  75. Determining if telomeres matter in colon cancer initiation or progression
  76. Gene expression modifications in Wharton’s Jelly mesenchymal stem cells promoted by prolonged in vitro culturing
  77. Oxidative damage and cellular defense mechanisms in sea urchin models of AGING
  78. Methylglyoxal alters the function and stability of critical components of the protein quality control
  79. Spermidine: a novel autophagy inducer and longevity elixir
  80. FOXOs attenuate bone formation by suppressing Wnt signaling
  81. Cellular AGING: symmetry evades senescence
  82. Zinc supplementation increases zinc status and thymopoiesis in aged mice
  83. Wholeness of the individual
  84. A wrinkle in time: Assessing the skin of older patients
  85. The origin of AGING: imperfectness-driven non-random damage defines the AGING process and control of lifespan
  86. Viral mediated expression of insulin-like growth factor I blocks the AGING-related loss of skeletal muscle function
  87. The second international conference “genetics of AGING and longevity”
  88. The short-lived fish Nothobranchius furzeri as a new model system for AGING studies
  89. Lipid peroxidation and the AGING process
  90. High brain lactate is a hallmark of AGING and caused by a shift in the lactate dehydrogenase A/B ratio
  91. A mouse model of accelerated liver AGING caused by a defect in DNA repair
  92. A biomarker that identifies senescent human cells in culture and in AGING skin in vivo
  93. Representative bibliography from Carlos López-Otín’s work
  94. AGING, rejuvenation, and epigenetic reprogramming: resetting the AGING clock
  95. Life spanning murine gene expression profiles in relation to chronological and pathological AGING in multiple organs
  96. Generation and gene expression of CD28-CD8 T-cells in human
  97. Position statement on human AGING
  98. Anxiety, AGING and the third emergency reaction
  99. Interview: Fighting disease from the chromosome end
  100. The canine as a model of human cognitive AGING: recent developments
  101. Isometric and isokinetic quadriceps muscle strength in 70-year-old men and women.
  102. The AGING oocyte—can mitochondrial function be improved?
  103. Living in a box or call of the wild? Revisiting lifetime inactivity and sarcopenia
  104. Premature AGING in mice deficient in DNA repair and transcription
  105. At loose ends: telomere theories of AGING and cancer begin to converge
  106. Testing Hypotheses of AGING in the Nematode Caenorhabditis elegans
  107. A divide-and-conquer assault on AGING: Mainstream at last
  108. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate AGING
  109. Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses
  110. Iatrogenesis in older individuals
  111. Modification upon AGING of the density of presynaptic modulation systems in the hippocampus
  112. Foxo Ladies Squander Their Eggs: Gene might link AGING with early ovarian failure in mice
  113. A longitudinal study of brain morphometrics using serial magnetic resonance imAGING analysis in a canine model of AGING
  114. Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span inSaccharomyces cerevisiae
  115. Dendritic stability in a model of adult-onset IGF-I deficiency
  116. Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle.
  117. Molecular Mechanisms in Hematopoietic Stem Cell AGING
  118. Effect of AGING on fertility and pregnancy
  119. Age-related changes of scleral hydration and sulfated glycosaminoglycans
  120. AGING of Premature-AGING Syndrome Cells
  121. C. elegans genetic networks predict roles for O-GlcNAc cycling in key signaling pathways
  122. Longevity‐assurance mechanisms and caloric restriction
  123. Where do Alzheimer’s plaques and tangles come from? AGING-induced protein degradation inefficiency
  124. The role of cellular senescence in skin AGING
  125. AGING, stem cells and tissue regeneration: lessons from muscle
  126. AGING-suppressants: cellular senescence (hyperactivation) and its pharmacologic deceleration
  127. Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature AGING associated with the deficiency of the circadian protein BMAL1
  128. The biologic clock: the mitochondria?
  129. Alterations of circadian rhythmicity and sleep in AGING: endocrine consequences
  130. Hyperphosphorylated tau in the brains of mice and monkeys with long-term administration of ketamine
  131. Inositol 1, 4, 5-trisphosphate receptor and ryanodine receptor in the AGING brain of Wistar rats
  132. Differential shortening rate of telomere length in the development of human fetus
  133. Expression of miR-146a and miR-16 in peripheral blood mononuclear cells of patients with rheumatoid arthritis and their correlation to the disease activity
  134. Cytomegalovirus genomes demonstrated by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients.
  135. Telomere length and cardiovascular AGING: the means to the ends?
  136. Understanding the biology of AGING: the key to prevention and therapy
  137. Differential expression of AGING biomarkers at different life stages of the annual fish Nothobranchius guentheri
  138. Good Timing: Defects in two proteins leave the body’s clock vulnerable to age-related breakdown
  139. Accurate quantification of more than 4000 mouse tissue proteins reveals minimal proteome changes during AGING
  140. Wnt signaling: it gets more humorous with age
  141. Noncanonical Wnt comes of age in hematopoietic stem cells
  142. Ink4a/Arf regulation by let-7b and Hmga2: a genetic pathway governing stem cell AGING
  143. Mitochondrial dysfunction
  144. Why do we need to age?
  145. Perceived age of facial features is a significant diagnosis criterion for age‐related carotid atherosclerosis in Japanese subjects: J‐SHIPP study
  146. Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span
  147. Nonhuman primate calorie restriction
  148. The PKB/FOXO switch in AGING and cancer
  149. Tissue-specific implications of mitochondrial alterations in AGING
  150. Detection of cytomegalovirus DNA in cells from synovial fluid and peripheral blood of patients with early rheumatoid arthritis.
  151. An anti-AGING drug today: from senescence-promoting genes to anti-AGING pill
  152. Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?
  153. Cellular and molecular correlates of AGING in the nervous system
  154. Laboratory Tests for the Anti-AGING Physician
  155. Senescence of the retinal pigmented epithelium.
  156. The anti-AGING sweepstakes: catalase runs for the ROSes
  157. Chromatin structure and transposable elements in organismal AGING
  158. Characteristics of high and low self-esteem in the elderly
  159. Effect of AGING on rat tissue peptidase activities
  160. Healthy ageing, but what is health?
  161. Rat retinal transcriptome: effects of AGING and AMD-like retinopathy
  162. Biological markers to determine eligibility in trials for community-acquired pneumonia: a focus on procalcitonin
  163. Insights into central and peripheral factors affecting the “oxidative performance” of skeletal muscle in AGING
  164. Oxidative stress and chronological AGING in glycogen-phosphorylase-deleted yeast
  165. Potential for control of oxidative injury by administration of antioxidants in veterinary medicine
  166. Mitochondrial DNA deletion mutations and sarcopenia
  167. Rapamycin extends life-and health span because it slows AGING
  168. The role of telomeres and telomerase in stem cell AGING
  169. Lamin B1 loss is a senescence-associated biomarker
  170. Inhibition of Krebs cycle and activation of glyoxylate cycle in the course of chronological AGING of Saccharomyces cerevisiae. Compensatory role of succinate oxidation
  171. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
  172. A natural product telomerase activator as part of a health maintenance program
  173. Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during AGING or oxidative stress
  174. Concurrent trigeminal, abducens, and facial nerve palsies presenting as false localizing signs: case report
  175. Age-related changes in regional cerebral blood flow and behavior in Sprague-Dawley rats
  176. Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotection
  177. Human immunodeficiency virus and acquired immunodeficiency syndrome: recent developments and their implications for pediatric surgeons.
  178. Effects of scopolamine challenge on regional cerebral blood volume. A pharmacological model to validate the use of contrast enhanced magnetic resonance imAGING …
  179. Stems cells and the pathways to AGING and cancer
  180. The impact of altered p53 dosage on hematopoietic stem cell dynamics during AGING
  181. Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men
  182. Protein quality control during AGING involves recruitment of the macroautophagy pathway by BAG3
  183. Metformin: do we finally have an anti-AGING drug?
  184. Life-spanning murine gene expression profiles in relation to chronological and pathological AGING in multiple organs
  185. Calorie restriction extends yeast life span by lowering the level of NADH
  186. Impaired Muscle Performance
  187. Redox regulation of tumor suppressor PTEN in cancer and AGING
  188. Bone Marrow Rejuvenation–An Excellent Potential Therapy for Age-Related Endothelial Dysfunction–
  189. Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly
  190. Protein homeostasis and AGING: role of ubiquitin protein ligases
  191. Iron load and redox stress in skeletal muscle of aged rats
  192. Solving puzzles of AGING: From disposable soma to signal-transduction pathways
  193. Physical training improves motor performance in people with dementia: a randomized controlled trial
  194. Caspase-2 deficiency enhances AGING-related traits in mice
  195. Newly identified roles for an old guardian: profound deficiency of the mitotic spindle checkpoint protein BubR1 leads to early AGING and infertility
  196. Accumulation of multipotent progenitors with a basal differentiation bias during AGING of human mammary epithelia
  197. Immunosuppressants in cancer prevention and therapy
  198. D-galactose toxicity in mice is associated with mitochondrial dysfunction: protecting effects of mitochondrial nutrient R-alpha-lipoic acid
  199. A senescence accelerated mouse model to study AGING in the larynx
  200. Targeting senescence pathways to reverse drug resistance in cancer
  201. Single-cell analysis: toward the clinic
  202. Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver
  203. Loss in oxidative stress tolerance with AGING linked to reduced extracellular signal‐regulated kinase and Akt kinase activities
  204. AGING is not programmed: genetic pseudo-program is a shadow of developmental growth
  205. Oxidative stress accumulates in adipose tissue during AGING and inhibits adipogenesis
  206. Alterations with AGING of the endocrine and neuroendocrine circadian system in humans
  207. Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents
  208. Common mechanisms for declines in oxidative stress tolerance and proliferation with AGING
  209. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
  210. Stromal-epithelial interactions in AGING and cancer: senescent fibroblasts alter epithelial cell differentiation
  211. Stimulation of macroautophagy can rescue older cells from 8-OHdG mtDNA accumulation: a safe and easy way to meet goals in the SENS agenda
  212. Melatonin, hydroxyl radical‐mediated oxidative damage, and AGING: a hypothesis
  213. Collateral damage: cardiovascular consequences of chronic sympathetic activation with human AGING
  214. The carbon starvation response of Aspergillus niger during submerged cultivation: insights from the transcriptome and secretome
  215. Effects of melatonin in elderly patients with sleep disturbance: a pilot study
  216. Do reaction time measures enhance diagnosis of early-stage dementia of the Alzheimer type
  217. Yeast longevity and AGING
  218. Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease
  219. Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats☆
  220. Molecular and chemical genetic approaches to developmental origins of AGING and disease in zebrafish
  221. Oxygen, antioxidants and brain dysfunction
  222. Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models
  223. An integrated view of oxidative stress in AGING: basic mechanisms, functional effects, and pathological considerations
  224. AGING in mice reduces the ability to sustain sleep/wake states
  225. Age‐related alterations in T‐lymphocytes modulate key pathways in prostate tumorigenesis
  226. Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during AGING
  227. Decorin expression is important for age-related changes in tendon structure and mechanical properties
  228. Mitochondrial DNA shifting in older adults following resistance exercise training
  229. Oxidative protein damage is associated with poor grip strength among older women living in the community
  230. Impact of AGING and senescence on phenotype and function of murine brain microglia in vitro and in vivo
  231. Effect of melatonin in selected populations of sleep-disturbed patients
  232. An increase in the association of GluN2B containing NMDA receptors with membrane scaffolding proteins was related to memory declines during AGING
  233. Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow–derived cells can alter the outcome of lung injury in aged …
  234. possible components of biological AGING. Experimental data are discussed with regard to alterations in myocardial function during the AGING process. Also
  235. Caloric restriction prevents AGING-associated changes in spike-mediated Ca2+ accumulation and the slow afterhyperpolarization in hippocampal CA1 pyramidal …
  236. Life Extension in the Short-Lived Fish Nothobranchius furzeri
  237. The search for evolutionary developmental origins of AGING in zebrafish: a novel intersection of developmental and senescence biology in the zebrafish model system
  238. Effect of calorie restriction on the metabolic history of chronologically AGING yeast
  239. Environmental influences on skin AGING and ethnic-specific manifestations
  240. Changes in primary lymphoid organs with AGING
  241. Human AGING and melatonin. Clinical relevance
  242. Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons
  243. Gliotoxin reverses age‐dependent nuclear morphology phenotypes, ameliorates motility, but fails to affect lifespan of adult Caenorhabditis elegans
  244. Polycomb group proteins in hematopoietic stem cell AGING and malignancies
  245. The transcriptome of prematurely AGING yeast cells is similar to that of telomerase-deficient cells
  246. Chromosomal Instability and AGING: Basic Science and Clinical Implications
  247. The Olive Constituent Oleuropein Exhibits Proteasome Stimulatory Properties In Vitro and Confers Life Span Extension of Human Embryonic Fibroblasts
  248. Fat and AGING: a tale of two tissues
  249. Circulating tumor cells and circulating tumor DNA
  250. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
  251. The great unravelling: chromatin as a modulator of the AGING process
  252. Age related changes of the extracellular matrix and stem cell maintenance
  253. 5 Psychosocial and behavioral dimensions of physical frailty
  254. AGING defined by a chronologic–replicative protein network in Saccharomyces cerevisiae: An interactome analysis
  255. Cardiac AGING in Female Wistar Rat Models With Sedentary or Physicaly Active Lifestyle
  256. Lymphoid neogenesis and immune infiltration in aged liver
  257. Physiological changes, fibroblast cells
  258. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
  259. Do age-related changes in DNA methylation play a role in the development of age-related diseases?
  260. Neurogenesis in the adult human hippocampus
  261. Effect of Nanoparticles on the Biochemical and Behavioral AGING Phenotype of the Nematode Caenorhabditis elegans
  262. THE PHYSIOLOGICAL BASIS OF DORIAN GRAY’S PORTRAIT
  263. Redox modulation of the liver with chronic antioxidant enzyme mimetic treatment prevents age‐related oxidative damage associated with environmental stress
  264. Regulation of insulin-like growth factor binding protein-1 expression during AGING
  265. Effect of a traditional Japanese herbal medicine, Hochu-ekki-to (Bu-Zhong-Yi-Qi Tang), on immunity in elderly persons
  266. Pessimism, age, and cancer mortality.
  267. Testosterone loss and estradiol administration modify memory in men
  268. Short‐term, light‐to moderate‐intensity exercise training improves leg muscle strength in the oldest old: a randomized controlled trial
  269. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during AGING
  270. Single cell metabolomics
  271. Muscle strength after resistance training is inversely correlated with baseline levels of soluble tumor necrosis factor receptors in the oldest old
  272. Alterations to nuclear architecture and genome behavior in senescent cells.
  273. Mitochondrial membrane lipidome defines yeast longevity
  274. Brain activation during encoding and recognition of verbal and figural information in older adults
  275. Current perspective on the global and United States cancer burden attributable to lifestyle and environmental risk factors
  276. Elevated histone expression promotes life span extension
  277. Brown adipose tissue thermogenesis during AGING and senescence
  278. The role of chondrocyte senescence in osteoarthritis
  279. Industrial Approaches Towards Developing Effective Skin Care Products
  280. A biodemographic interpretation of life span
  281. Systemic effects of inflammation on health during chronic HIV infection
  282. Longevity Regulation in Saccharomyces cerevisiae: Linking Metabolism, Genome Stability, and Heterochromatin
  283. Distinct signature of altered homeostasis in AGING rod photoreceptors: implications for retinal diseases
  284. Cellular heterogeneity and molecular evolution in cancer
  285. Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during AGING
  286. Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia
  287. Muscles–Not Just for Bodybuilders!
  288. Changes in maximal aerobic capacity with age in endurance-trained women: 7-yr follow-up
  289. Telomerase and telomere dysregulation in polychlorinated biphenyl (PCB) exposed human skin keratinocytes
  290. Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans
  291. Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
  292. Reactive oxygen species (ROS) protection via cysteine oxidation in the epidermal cornified cell envelope
  293. AGING alters PPARγ in rodent and human adipose tissue by modulating the balance in steroid receptor coactivator‐1
  294. Cancer and inflammation: an old intuition with rapidly evolving new concepts
  295. Iatrogenic disease in the elderly: risk factors, consequences, and prevention
  296. Pathophysiology of the AGING kidney and therapeutic interventions
  297. Effect of antioxidant diets on mitochondrial gene expression in rat brain during AGING
  298. Engineered culture models for studies of tumor-microenvironment interactions
  299. Vision deficits precede structural losses in a mouse model of mitochondrial dysfunction and progressive retinal degeneration
  300. High-abundance mRNAs in human muscle: comparison between young and old
  301. Characteristics of Hippocampal Theta, Gamma, and Theta-Gamma Coupling: Effects of AGING, Environmental Change, and Cholinergic Activation
  302. Vascular smooth muscle cell polyploidy: an adaptive or maladaptive response?
  303. Changes in somatodendritic but not terminal dopamine regulation in aged rhesus monkeys
  304. Immune effects of hormone replacement therapy in post-menopausal women
  305. Tpo1‐mediated spermine and spermidine export controls cell cycle delay and times antioxidant protein expression during the oxidative stress response
  306. Early life stress and telomere length: investigating the connection and possible mechanisms: a critical survey of the evidence base, research methodology and basic …
  307. Mutations arising during repair of chromosome breaks
  308. Biological and clinical consequences of longitudinal studies in rodents: their possibilities and limitations. An overview
  309. Molecular mechanism of PPAR in the regulation of age-related inflammation
  310. AGING does not affect contractile properties of type IIb FDL muscle in Fischer 344 rats
  311. Skeletal muscle mass and the reduction ofV˙o 2 max in trained older subjects
  312. Prevention of N-Methyl-N-Nitrosourea-Induced Mammary Carcinogenesis in Rats by 1α-Hydroxyvitamin D5
  313. Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease
  314. Healthy ageing, but what is health?
  315. Musical experience strengthens the neural representation of sounds important for communication in middle-aged adults
  316. Effects of muscle strength training and megestrol acetate on strength, muscle mass, and function in frail older people
  317. AGING of skeletal muscle: a 12-yr longitudinal study
  318. Immunology and AGING
  319. AGING stem cells, latexin and longevity
  320. Invited review: AGING and sarcopenia
  321. Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration
  322. Ageing purpose: another thrifty genotype
  323. Zinc and the liver: an active interaction
  324. Autophagy and AGING—importance of amino acid levels
  325. Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy
  326. TOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists
  327. Myogenic gene expression at rest and after a bout of resistance exercise in young (18–30 yr) and old (80–89 yr) women
  328. Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
  329. The PI3K, metabolic, and autophagy networks: interactive partners in cellular health and disease
  330. Cytomegalovirus antibodies in dried blood spots: a minimally invasive method for assessing stress, immune function, and AGING
  331. Chromosomal aneuploidy in the AGING brain
  332. Symposium: Popular Literature on AGING
  333. A randomized trial of weighted vest use in ambulatory older adults: strength, performance, and quality of life outcomes
  334. Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases
  335. The adult Drosophila posterior midgut is maintained by pluripotent stem cells
  336. Cardiovascular effects of AGING in primates—gender differences
  337. Can O2 Dysregulation Induce Premature AGING?
  338. Sirtuins, tissue maintenance, and tumorigenesis
  339. Heart failure in the oldest patients: the impact of comorbid conditions
  340. Cerebrospinal fluid concentrations of corticotropin‐releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: Response to …
  341. Cutaneous innervation in Guillain–Barré syndrome: pathology and clinical correlations
  342. The pathogenesis of susceptibility to acute kidney injury in the elderly
  343. Circadian clock proteins control adaptation to novel environment and memory formation
  344. Spend less, live longer. The “thrifty aged” hypothesis
  345. Statement by the Growth Hormone Research Society on the GH/IGF-I axis in extending health span
  346. Mechanisms of visual-cognitive AGING: A neural network account
  347. Identification of mitochondrial dysfunction in Hutchinson–Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture
  348. Characteristics of muscle fiber type are predictive of skeletal muscle mass and strength in elderly men
  349. Controversies regarding hormone therapy: Insights from inflammation and hemostasis
  350. A walking program for nursing home residents: effects on walk endurance, physical activity, mobility, and quality of life
  351. Reduced muscle oxidative capacity is independent of O 2 availability in elderly people
  352. Influence of dietary factors on the longevity of Drosophila
  353. Evidence for the influence of vitamin C on age-and heat exposure-dependent deterioration of biochemical function in rat’s liver and kidney
  354. Exploring Mechanisms of AGING Retardation by Caloric Restriction: Studies in Model Organisms and Mammals
  355. Mitochondrial dysfunction in brain AGING: role of oxidative stress and cardiolipin
  356. Prolongation of Life Span in the Accelerated AGING klotho Mouse Model, by Low-Dose-Rate Continuous γ Irradiation
  357. Caloric restriction and experimental carcinogenesis
  358. Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction
  359. Tissue resident stem cells: till death do us part
  360. Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation
  361. Exploring a ‘pro-senescence’approach for prostate cancer therapy by targeting PTEN
  362. Oxidative stress, mitochondrial bioenergetics, and cardiolipin in AGING
  363. New targets for the identification of an anti-inflammatory anti-senescence activity
  364. C/EBPα and β couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation
  365. Selective anticancer agents suppress AGING in Drosophila
  366. Oxidative AGING and insulin receptor signaling
  367. The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation
  368. Alkaline salts to counteract bone resorption and protein wasting induced by high salt intake: results of a randomized controlled trial
  369. Expression of inhibin α, glial cell line-derived neurotrophic factor and stem cell factor in Sertoli cell-only syndrome: relation to successful sperm retrieval by …
  370. Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis
  371. The cardiocyte in senescence
  372. Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and AGING
  373. Physical exercise in the oldest old
  374. Cognitive and behavioral consequences of impaired immunoregulation in AGING
  375. Energy intake and leukocyte telomere length in young adults
  376. Brain cholesterol in normal and pathological AGING
  377. Identification of longevity genes with systems biology approaches
  378. Folding proteins in fatal ways
  379. Aberrant insulin receptor signaling and amino acid homeostasis as a major cause of oxidative stress in AGING
  380. Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
  381. Attenuation of cardiovascular adaptations to exercise in frail octogenarians
  382. Facial rejuvenation and volumization using implants
  383. Jekyll and Hyde, the p53 protein, pleiotropics antagonisms and the thrifty aged hypothesis of senescence
  384. Fructose-1, 6-bisphosphatase mediates cellular responses to DNA damage and AGING in Saccharomyces cerevisiae
  385. Effects of caloric restriction on gene expression along the epididymis of the Brown Norway rat during AGING
  386. Aged rats need a preserved complement of perforated axospinous synapses per hippocampal neuron to maintain good spatial memory
  387. The coordination of nuclear and mitochondrial communication during AGING and calorie restriction
  388. Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with AGING
  389. Extending lifespan using various prolongevity interventions and their effects on enhancing dna repair activity
  390. Microarray analysis of gene expression changes in AGING
  391. The emerging role of IGF-1 deficiency in cardiovascular AGING: recent advances
  392. Characterization of the androgen-regulated prostate-specific T cell receptor γ-chain alternate reading frame protein (TARP) promoter
  393. Novel combinations of post-translational modification (PTM) neo-epitopes provide tissue-specific biochemical markers—are they the cause or the consequence of the …
  394. Why physiology matters in medicine
  395. Age-dependent spatial memory loss can be partially restored by immune activation
  396. Effects of epigenetic drugs (vorinostat, decitabine) on metabolism-related pathway factors in leukemic cells
  397. The influence of UVB radiation on proliferation and Youngs modulus of dermal fibroblasts
  398. Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: implication to age-associated bone …
  399. SIRT6 and Premature AGING of Hutchinson-Gilford Progeria Syndrome Fibroblasts.
  400. Mitochondrial DNA damage level determines neural stem cell differentiation fate
  401. Adult‐onset deficiency in growth hormone and insulin‐like growth factor‐I alters oligodendrocyte turnover in the corpus callosum
  402. Identification of biomarkers of human skin ageing in both genders. Wnt signalling-a label of skin ageing?
  403. Genes encoding longevity: from model organisms to humans
  404. miR‐182 is a negative regulator of osteoblast proliferation, differentiation, and skeletogenesis through targeting FoxO1
  405. Pleiotropic cellular functions of PARP1 in longevity and AGING: genome maintenance meets inflammation
  406. Caspase‐independent cytochrome c release is a sensitive measure of low‐level apoptosis in cell culture models
  407. Werner syndrome cells escape hydrogen peroxide‐induced cell proliferation arrest
  408. Nuclear factor (erythroid-derived 2)-like-2 factor (Nrf2), a key regulator of the antioxidant response to protect against atherosclerosis and nonalcoholic steatohepatitis
  409. The effect of L-deprenyl on behavior, cognitive function, and biogenic amines in the dog
  410. Growth hormone, insulin-like growth factor-1, and the biology of AGING
  411. C/EBP homologous protein drives pro-catabolic responses in chondrocytes
  412. Gadd45 proteins: relevance to AGING, longevity and age-related pathologies
  413. PTEN controls β‐cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a
  414. Timing and AGING: slowing of fastest regular tapping rate with preserved timing error detection and correction.
  415. Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells
  416. Lifelong protection from global cerebral ischemia and reperfusion in long-lived Mclk1+/− mutants
  417. Comorbidity: a multidimensional approach
  418. Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent
  419. Proteasome function and protein oxidation in the aged retina
  420. Alcohol use and risk of pancreatic cancer: the NIH-AARP Diet and Health Study
  421. Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog
  422. Insulin-like growth factor isoforms in skeletal muscle AGING, regeneration, and disease
  423. Ileal perforation caused by cytomegalovirus infection in an immunocompetent adult
  424. Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteins
  425. Melatonin in AGING and disease—multiple consequences of reduced secretion, options and limits of treatment
  426. Longitudinal changes in aerobic power in older men and women
  427. Calorie restriction enhances T-Cell–mediated immune response in adult overweight men and women
  428. Heritability of the retinal microcirculation in Flemish families
  429. Sirtuins in hematological AGING and malignancy
  430. Hormonal and growth factor responses to heavy resistance exercise protocols
  431. mVps34 is activated following high‐resistance contractions
  432. Thiol supplementation in aged animals alters antioxidant enzyme activity after heat stress
  433. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
  434. Expression profile of Wnt isoforms during differentiation of AGING C2C12 myoblast cells.
  435. 24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma
  436. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia
  437. Micrometric scale measurement of material structure moving utilizing μ-radiographic technique
  438. Examination of the expanding pathways for the regulation of p21 expression and activity
  439. Genome-wide analysis of yeast AGING
  440. Force-generation capacity of single vastus lateralis muscle fibers and physical function decline with age in African green vervet monkeys
  441. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
  442. DNA methylation: a promising landscape for immune system-related diseases
  443. Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy: part I1
  444. HSF1-Controlled and Age-Associated Chaperone Capacity in Neurons and Muscle Cells of C. elegans
  445. Grade 3/4 neutropenia is a limiting factor in second-line FOLFIRI following FOLFOX4 failure in elderly patients with metastatic colorectal cancer
  446. Mutations in DNA replication genes reduce yeast life span
  447. Central role for the Werner syndrome protein/poly (ADP-ribose) polymerase 1 complex in the poly (ADP-ribosyl) ation pathway after DNA damage
  448. Macromitophagy is a longevity assurance process that in chronologically AGING yeast limited in calorie supply sustains functional mitochondria and maintains …
  449. Ethics, AGING, and society: The critical turn
  450. Limited expansion of virus-specific CD8 T cells in the aged environment
  451. AT cell model for age-related loss of homeostasis: Identification of the cell type responsible for age-related delay in recovery of the PHA-induced mitogenic response …
  452. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
  453. Age-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47
  454. The involvement of epigenetic silencing of Foxa2 in cellular replicative and premature senescence induced by hydrogen peroxide
  455. Androgen receptor footprint on the way to prostate cancer progression
  456. Effects of a mitochondrial mutator mutation in yeast POS5 NADH kinase on mitochondrial nucleotides
  457. An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women
  458. Resistance training reduces whole-body protein turnover and improves net protein retention in untrained young males
  459. Increased shelterin mRNA expression in peripheral blood mononuclear cells and skeletal muscle following an ultra-long-distance running event
  460. Hemoglobin A1c and arterial and ventricular stiffness in older adults
  461. Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion
  462. Towards measurement of the Healthy Ageing Phenotype in lifestyle-based intervention studies
  463. Autophagy promotes survival in AGING submerged cultures of the filamentous fungus Aspergillus niger
  464. Spermidine based ameliration of Age-dependent memory impairment under the paradigms of enhanced autophagy and altered epigenome in Drosophila …
  465. Neural dedifferentiation in relation to risk for Alzheimer’s disease
  466. Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates
  467. Circadian rhythms during AGING
  468. Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2
  469. Poly (ADP-ribosyl) ation, PARP, and AGING
  470. Mitochondrial Diseases, Treatments, and FDA Orphan Legislation
  471. Opposing effects of cortisol and dehydroepiandrosterone on the expression of the receptor for activated C kinase 1: implications in immunosenescence
  472. Pathways Change in Expression During Replicative AGING in Saccharomyces cerevisiae
  473. Metabolic Regulation of Gene Silencing and Life Span
  474. Mitochondria, metabolism, and AGING in yeast
  475. Age-dependent modulation of cortical transcriptomes in spinal cord injury and repair
  476. Cellular glucose sensing, energy metabolism, and AGING in Saccharomyces cerevisiae
  477. Human muscle satellite cells show age-related differential expression of S100B protein and RAGE
  478. LIF is a contraction-induced myokine stimulating human myocyte proliferation
  479. Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6
  480. The malate–aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast
  481. Prolonged overexpansion of extracellular water in elderly patients with sepsis
  482. Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction
  483. Thiol supplementation in aged animals alters antioxidant
  484. How does access to this work benefit you? Let us know!
  485. GW24-e3920 Correlation Analysis between Concentration of Serum Uric Acid and Risk Factors of Cardiovascular Disease in Population of Healthy Examination
  486. Cellular degradation machineries in age-related loss of muscle mass (Sarcopenia)
  487. Effect of chronic contractile activity on mRNA stability in skeletal muscle
  488. Eccentric contraction-induced injury to type I, IIa, and IIa/IIx muscle fibers of elderly adults
  489. SIR2 and other genes are abundantly expressed in long-lived natural segregants for replicative AGING of the budding yeast Saccharomyces cerevisiae
  490. NAD+ metabolism: A therapeutic target for age-related metabolic disease
  491. Unraveling the role of FoxOs in bone—insights from mouse models
  492. Life-extending ovariectomy in grasshoppers increases somatic storage, but dietary restriction with an equivalent feeding rate does not
  493. Basic Science and Clinical Implications
  494. Acute kidney injury in the elderly: pathogenesis, diagnosis and therapy
  495. SNF1/AMPK pathways in yeast
  496. Pain and Discomfort Avoidance
  497. Identification of novel modifiers of Aβ toxicity by transcriptomic analysis in the fruitfly
  498. Cell AGING: molecular mechanisms and implications for disease
  499. Informal caregivers in the United States: prevalence, caregiver characteristics, and ability to provide care
  500. Carbon starvation in the filamentous fungus Aspergillus niger
  501. Depletion of Dnmt1-associated protein 1 triggers DNA damage and compromises the proliferative capacity of hematopoietic stem cells
  502. Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis
  503. O ur sense of self-worth largely depends on a belief that we are leading
  504. Regeneration of the exocrine pancreas is delayed in telomere-dysfunctional mice
  505. Immediate effects of an 8-h advance shift of the rest-activity cycle on 24-h profiles of cortisol
  506. A reduction in age-enhanced gluconeogenesis extends lifespan
  507. Revisiting Alzheimer’s Disease from a New Perspective: Can “Risk Factors” Play a Key Role?
  508. The Role of the Nrf2 Dimerization Partner Maf-S in Drosophila Gene Regulation, Stress Response and AGING
  509. Psychobiological effects of juvenile violence exposure: effects on telomere erosion
  510. A possible link between iron deficiency and gastrointestinal carcinogenesis
  511. Cutaneotropic human β-/γ-papillomaviruses are rarely shared between family members
  512. Sertoli cells dictate spermatogonial stem cell niches in the mouse testis
  513. Role of Tos3, a Snf1 Protein Kinase Kinase, during Growth of Saccharomyces cerevisiae on Nonfermentable Carbon Sources
  514. Fast forwarding pharmacogenomics
  515. The relationship between Snf1 and AGING in Saccharomyces cerevisiae
  516. Calorie restriction and the nutrient sensing signaling pathways
  517. Mitochondrial dysfunction and cellular metabolic deficiency in Alzheimer’s disease
  518. Biological aspects of human ageing
  519. Accumulation of Multipotent Progenitors with a Basal
  520. Impact of sleep deprivation on insulin secretion, insulin sensitivity, and other hormonal regulations
  521. Rapamycin induces pluripotent genes associated with avoidance of replicative senescence
  522. Snf1 kinases with different β-subunit isoforms play distinct roles in regulating haploid invasive growth
  523. Nitric oxide in the regulation of the sleep-wake states
  524. Longevity in radiated human populations, with particular reference to the atomic bomb survivors
  525. Physiological genetics of dietary restriction: uncoupling the body temperature and body weight responses
  526. Kidney function and disease in the elderly
  527. Cyclic AMP-dependent protein kinase regulates the subcellular localization of Snf1-Sip1 protein kinase
  528. Cancer and AGING handbook: research and practice
  529. The postmitotic Saccharomyces cerevisiae after spaceflight showed higher viability
  530. Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle
  531. Activation of chaperone-mediated autophagy during oxidative stress
  532. High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression
  533. The AGING Male and Impact on Offspring
  534. ManAGING cardiovascular risk reduction in elderly adults
  535. Geriatric Syndromes Defined and Explained for Oncology Practice
  536. Age-related sympathetic autonomic neuropathology
  537. Diagnosis of dementia in the elderly: A 1980 perspective
  538. Diagnosis and treatment of dementia in the aged
  539. Effects of a leucine and pyridoxine-containing nutraceutical on body weight and composition in obese subjects
  540. Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase
  541. AGING and human motivation
  542. Rothmund-thomson syndrome
  543. Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults
  544. DNA repair and genomic instability in yeast AGING
  545. Non-enzymatic covalent modifications of proteins: mechanisms, physiological consequences and clinical applications
  546. Autophagy and cellular immune responses
  547. The budding yeast nuclear envelope adjacent to the nucleolus serves as a membrane sink during mitotic delay
  548. Metabolic roles of poly (ADP-ribose) polymerases
  549. Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes
  550. cardiac Anesthesia and Surgery in geriatric patients: Epidemiology, current Surgical outcomes, and future directions
  551. Relationship between muscle sympathetic nerve activity and systemic hemodynamics during nitric oxide synthase inhibition in humans
  552. Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin …
  553. Nineteenth-Century British Children’s Literature
  554. IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle
  555. A Social and Biomedical Perspective
  556. Nicotinamide adenine dinucleotide extends the lifespan of Caenorhabditis elegans mediated by sir-2.1 and daf-16
  557. The role of genetic variants in human longevity
  558. Effects of age on coping and psychological distress in women diagnosed with breast cancer: review of literature and analysis of two different geographical settings
  559. Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice
  560. T here is a much exaggerated image of the baby boomers descend
  561. Defective Mitochondrial Function In Vivo in Skeletal Muscle in Adults with Down’s Syndrome: A 31P-MRS Study
  562. Consequences of miRNA misregulation on embryonic development and AGING
  563. Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1
  564. Testing the potential for Muscle Polyubiquitination as an AGING Biomarker in Drosophila
  565. Oxidative Stress and AGING of the Male Reproductive Tract
  566. Oxidative stress and AGING of the male reproductive tract
  567. Removing all obstacles: a critical role for p53 in promoting tissue renewal
  568. Invited Review: An Integrated View of Oxidative Stress in AGING: Basic Mechanisms, Functional Effects and Pathological Considerations
  569. Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity
  570. Intermittent fasting in athletes: PROs and CONs
  571. Impact of lifelong sedentary behavior on mitochondrial function of mice skeletal muscle
  572. Leukocyte Telomere Length and Lens Tansparency as Biomarkers in Population Studies of Human AGING
  573. Molecular mechanisms of spatial protein quality control
  574. Expression of TrkB at the neuromuscular junction during AGING
  575. Metformin increases the PGC-1α protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo
  576. Clinical implications of oxidative stress and antioxidant therapy
  577. Astrocyte elevated gene-1, a novel modulator of astrocyte function: implications for neuroaids, AGING and glioblastoma
  578. JNK3 perpetuates metabolic stress induced by Aβ peptides
  579. AGING, Breast Cancer and the Mouse Model
  580. Genetic and epigenetic effects of nanoparticles
  581. Genetic and biochemical studies on hepatocytes of young and old heat-stressed rats
  582. A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
  583. –Non-surgical Facial Rejuventation with Fillers
  584. Age-related oxidative modifications of transthyretin modulate its amyloidogenicity
  585. Challenging the Limits of the Human Life Span:-Can We Live Longer Than 120 Years-New Guidelines
  586. Quantification of endogenous sirtuin metabolite O-acetyl-ADP-ribose
  587. Avoiding the First Cause of Death: Can We Live Longer and Better?
  588. It takes nerves to fight infections: insights on neuro-immune interactions from C. elegans
  589. Involvement of SIRT1 in Zn2+, streptozotocin, non-obese diabetic, and cytokine-mediated toxicities of β-cells
  590. ManAGING cardiovascular risk reduction in elderly adults
  591. ly Sunscreens Do Not uUy Prevent
  592. Redox Regulation of Sirtuin-1 by S-Glutathiolation
  593. Transplantation in the elderly patient
  594. Genetic analysis of tissue AGING in Caenorhabditis elegans
  595. Problems and solutions to the development of vaccines in the elderly
  596. Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal
  597. HIDDEN COSTS OF EFFORTFUL LISTENING ON SPEECH COMPREHENSION.
  598. Selective modulation of protein kinase AI and II reveals distinct roles in thyroid cell gene expression and growth
  599. The Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress
  600. Ovarian abnormalities in a mouse model of fragile X primary ovarian insufficiency
  601. Interaction of contractile activity and training history on mRNA abundance in skeletal muscle from trained athletes
  602. Proteostasis as a signaling device and therapeutic target
  603. A 1980 Perspective
  604. Presbyacusis and presbyastasis
  605. Diffusion tensor imAGING: technique, clinical and research applications
  606. Modulation of sirtuins: new targets for antiageing
  607. A lifetime passion for micronucleus cytome assays—reflections from Down Under
  608. Effects of estrogen on cognition: Implications for menopause.
  609. Sleep and diabesity in older adults
  610. Shifts of the hormonal rhythms of melatonin and cortisol after a 4 h bright‐light pulse in different diurnal types
  611. Behavioral changes and mechanisms–an experimental study on AGING in rodents
  612. Forkhead box (O) in control of reactive oxygen species and genomic stability to ensure healthy lifespan
  613. Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence
  614. 26 Surgical rejuvenation of the neck
  615. Surgical rejuvenation of the neck
  616. 14 Calorie Restriction
  617. 14 Calorie Restriction, Mitochondria, and Longevity in Saccharomyces cerevisiae
  618. Leads from xenobiotic metabolism genes for Parkinson’s disease among north Indians
  619. AMPK and SIRT1: a long-standing partnership?
  620. Stress, infection, and AGING in guppies (Poecilia reticulata): An evolutionary approach
  621. Using atomic force microscope to investigate the influence of UVB radiation on cell behaviour and elasticity of dermal fibroblasts
  622. Rubin’s pathology: clinicopathologic foundations of medicine
  623. Metformin’s performance in in vitro and in vivo genetic toxicology studies
  624. Mother cell-specific ageing
  625. Oxidative stresses and ageing
  626. Autophagosome formation and molecular mechanism of autophagy
  627. Protein and amino acid supplementation in older humans
  628. Mitochondrial genome variation in healthy AGING
  629. Signaling in muscle atrophy and hypertrophy
  630. Characterization of the antiAGING effects of apple phytochemicals using the Caenorhabditis elegans model
  631. Yeast POS5 NADH Kinase: Effects of a Mitochondrial Mutator Mutation on Mitochondrial Nucleotides
  632. Defective Mitochondrial Function In Vivo in Skeletal Muscle in Adults with Down’s
  633. Neurobiological Substrates of Age-Associated Decline in Neuronal Excitability-Lipid Peroxidation-Dependent Modulation of Transient Potassium Current Inactivation?
  634. Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB …
  635. BDNF rescues myosin heavy chain IIB muscle fibers after neonatal nerve injury
  636. In Pursuit of a Molecular Fountain of Youth: The Identification and Characterization of Lifespan Regulators in Drosophila
  637. Studies of molecular mechanisms of cranberry mediated healthspan promotion in Caenorhabditis elegans
  638. Invited review: intracellular signaling in contracting skeletal muscle
  639. Characterization of the 26S proteasome in Drosophila melanogaster as a model for AGING
  640. Overview: what are helicases?
  641. Vital mitochondrial functions show profound changes during yeast culture ageing
  642. Regional variations in ABC transporter expression along the mouse intestinal tract
  643. Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids
  644. The role of immunosenescence in autoimmune/autoinflammatory pathogenesis of Behçet’s disease
  645. Age-related changes in adrenomedullin expression and hypoxia-inducible factor-1 activity in the rat lung and their responses to hypoxia
  646. Mitotic checkpoint, aneuploidy and cancer
  647. Diagnosis and screening
  648. Spatial localization of A2E in the retinal pigment epithelium
  649. Oxidative stress and signal transduction in Saccharomyces cerevisiae: insights into ageing, apoptosis and diseases
  650. Old-age muscle atrophy: Cellular mechanisms and behavioral consequenses
  651. Neuroprotection by adenosine receptors in aged rats–role of neuroinflammation
  652. Glutathione content and adaptation to endogenously induced energy depletion in Mv1Lu cells
  653. Current Status for Cord Blood Transplantation and Public Cord Blood Bank in Korea
  654. Nonlinear regression models for determination of nicotinamide adenine dinucleotide content in human embryonic stem cells
  655. AGING: A New Problem of Modern Medicine
  656. Cellular and molecular characterization of oxidative stress in olfactory epithelium of Harlequin mutant mouse
  657. Age-associated alterations to sperm DNA methylation and possible consequences on the offspring
  658. Influenza update: a review of currently available vaccines
  659. Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism
  660. The life span perspective
  661. Multiple Memory Systems in a Rat Model of Neurocognitive AGING
  662. Augmentation mastopexy
  663. Sugar sensing and signaling in plants
  664. NAD+ maintenance attenuates light induced photoreceptor degeneration
  665. Multivariate Anti-inflammatory Approaches to Rescue Neurogenesis and Cognitive function in Aged Animals
  666. The determinants of mortality
  667. The Cholesterol Wars: The Skeptics vs the Preponderance of Evidence
  668. Influence of chronological AGING on the survival and nucleotide content of Saccharomyces cerevisiae cells grown in different conditions: occurrence of a high concentration of …
  669. Evidence for the involvement of CaMKII and AMPK in Ca2+-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle
  670. Yeast as a model for ageing and apoptosis research
  671. Methods for brain iron evaluation in normal AGING: T2 and phase measurements at 3 Tesla and 7 Tesla
  672. Metabolism and life span determination in C. elegans
  673. The Parental Co-Immunization Hypothesis
  674. Serum inflammatory markers in obstructive sleep apnea: a meta-analysis
  675. Maps on Public Display for Tourists in Ayutthaya, Thailand
  676. Novel methods and applications of weighted gene coexpression network analysis
  677. AGING and Sleep Stage Effects on Entropy of Electroencephalogram Signals
  678. Functions, cooperation, and interplays of the vegetative growth signaling pathway in the Aspergilli
  679. The Quality of Science and Engineering at the NNSA National Security Laboratories
  680. Oxidative damage to proteins: structural modifications and consequences in cell function
  681. Insomnia: Its Causes, Its Consequences, and Its Cures
  682. The Care and Feeding of the Leaders Brain
  683. Exploring Functional Links Between Circadian Clocks, Neurodegeneration, and AGING in Drosophila melanogaster
  684. Age-related variation in synapse number in rat sensorimotor cortex and hippocampus and the effect of insulin-like growth factor-1 treatment
  685. The visibility of moire fringe patterns
  686. Akt modes of stem cell regulation: more than meets the eye?
  687. Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes
  688. Age-related alterations in transcriptional regulation of hepatic glutathione synthesis: Remediation by R-alpha-lipoic acid
  689. MR microscopy and high resolution small animal MRI: applications in neuroscience research
  690. Health promotion for the elderly
  691. Vascular calcification and uremia: what do we know?
  692. Prenatal dexamethasone augments the sex-selective developmental neurotoxicity of chlorpyrifos: implications for vulnerability after pharmacotherapy for preterm labor
  693. Structural studies of Sir2 enzyme mechanism
  694. Primary and secondary prevention strategies among older postmenopausal women
  695. Research Journal of Pharmaceutical, Biological and Chemical Sciences
  696. A lifespan-extending form of autophagy employs the vacuole-vacuole fusion machinery
  697. Molecular Mechanisms of Sleep/Wake Regulation and Memory Formation in Young and Aged Mice
  698. Extracellular matrix remodeling: the common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more …
  699. mTOR and its Physiological Impacts-Part I: An Overview
  700. Mitochondrial dysfunction in cancer
  701. CHARACTERIZING THE ACUTE MITOCHONDRIAL RESPONSE TO RESISTANCE EXERCISE IN AGING
  702. Quantitative molecular genetics of longevity in Drosophila melanogaster
  703. Sleep well
  704. Control of protein degradation pathways by BAG proteins and changes during AGING
  705. Cellular Defects in Hutchinson-Gilford Progeria Syndrome
  706. Mitochondrial plasticity in pathophysiological conditions
  707. Physiological characterization of glucose repression in the strains with SNF1 and SNF4 genes deleted
  708. The human Lon protease in mitochondrial stress protection and AGING
  709. The effects of acquired hearing loss on the psychosocial functioning of seniors
  710. Impact of Oxidative Stress on Female Fertility.
  711. Common threads in atrial fibrillation and heart failure
  712. Orphanet Journal of Rare Diseases
  713. C0045 Skeletal Muscle Degeneration and Regeneration in Mice and Flies
  714. A life-span theory of control
  715. Cell injury
  716. High-Affinity Transporters for NAD+ Precursors in Candida glabrata Are Regulated by Hst1 and Induced in Response to Niacin Limitation
  717. Regulation of the Sir2 family of deacetylases
  718. Old-Age Muscle Atrophy: Cellular Mechanisms and Behavioral Consequences
  719. Avenanthramide supplementation in young and older women: Protection against eccentric exercise-induced inflammation and oxidative stress
  720. Correlation between inactive cathepsin D expression and retinal changes in mcd2/mcd2 transgenic mice
  721. Cbl-b: its role of expression and regulation in T-lymphocyte activation and ageing
  722. A reduced zinc diet or zinc transporter 3 knockout attenuate light induced zinc accumulation and retinal degeneration
  723. About AGEs
  724. Master stem cell transcription factors and signaling regulation
  725. Diagnosis and treatment of tumors of the urinary bladder
  726. Differential regulation of E2F transcription factors by p53 tumor suppressor protein
  727. Transcriptional control of glucose homeostasis through SIRT1 and PGC-1alpha
  728. Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease
  729. Stuff & Stuff
  730. Reduced Surrogate Light Chain in Old B Cell Precursors Compromises B Lymphopoiesis and Increases B Cell Reactivity to Common Self Antigens
  731. DNA adducts as biomarkers of exposure to some dietary carcinogens
  732. Mechanisms for the anti-inflammatory effects of exercise training
  733. Mitochondrial Determinants of Longevity in Mammals
  734. Functional neuroimAGING of cognition
  735. Regulation of yeast and metazoan lifespan by sirtuins and the NAD (+) salvage pathway
  736. TFIIH: at the crossroads of cancer and ageing
  737. MUTATIONS IN HUMAN HISTONE H3 ARE PRE-LEUKEMIC EVENTS THAT PROMOTE
  738. Fibrinogen chaperone activity in transthyretin amyloidosis: the effect of protein glycation
  739. Beta-catenin signaling occurs in progenitors of the adult nervous system and increases in NG2+ progenitors and astrocytes during posttraumatic gliogenesis
  740. Functional outcomes of polarization, morphology, and intracellular trafficking in Saccharomyces cerevisiae
  741. Tdh3 (a GAPDH isozyme) is a novel regulator of Sir2-mediated transcriptional silencing in yeast
  742. A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress
  743. High-affinity transporters for NAD+ precursors in Candida glabrata are regulated by Hst1 and induced in
  744. Role of p53 and p66shc during cellular senescence and early embryonic arrest in the bovine
  745. Essential functions in bacteria: from a genome-wide to a single-cell perspective
  746. Health promotion in the elderly: Changes in endocrine function after three months of modern or traditional treatment
  747. Converging Pathways in the Regulation of Longevity and Metabolism in Caenorhabditis Elegans: A Dissertation
  748. Insights into Calorie Restriction and Life Span Extension: Characterization of the Longevity Mediators Whi2 and Nitric Oxide in Saccharomyces cerevisiae
  749. Probing control mechanisms of cell cycle and ageing in budding yeast
  750. Bcl-2 promoted alterations in gene expression: A structure to function study
  751. Social withdrawal and psychological well-being in older adults
  752. Effects of age on the sexually dimorphic brain and the suprachiasmatic nucleus: Impact on the female reproductive system
  753. Redox-mediated inhibition of the human heat shock transcription factor 1 activation involves intramolecular disulfide bond formation
  754. Phenotypic heterogeneity in clonal bacterial populations: on origins and adaptive functions
  755. Investigation Of Dopamine Dynamics In Bdnf+/-Mice Using In Vivo Microdialysis And Electrochemical Analysis Of Purine And Monoamine Molecules Using A …
  756. Identification and characterization of novel longevity regulators in metabolic pathways in the yeast Saccharomyces cerevisiae
  757. Double Menopause: What to do when both you and your mate go through hormonal changes together
  758. Examination of endocrine disruptor effects in neuroendocrine systems, in vivo and in vitro
  759. How to Talk With Your Doctor: Easyread Edition
  760. The Bone-Building Solution
  761. Mother in the Middle: A Biologist’s Story of Caring for Parent and Child
  762. Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue Diseases
  763. Control of DNA replication in vivo: study of mouse models for Cdc6 and Cdt1 overexpression
  764. Mechanistic insights into antiviral resistance, mitochondrial toxicity, and design of novel HIV-1 reverse transcriptase inhibitors
  765. Defining a genetic framework for stem cell niche maintenance in the Drosophila testis
  766. New pathways of NAD+ metabolism and longevity
  767. Restore the Flow: Natural Health and Proactive Faith for the Fullness of Life
  768. Nutrient and hormonal control of the protein deacetylase SIRT1
  769. Investigating the mechanism of GABA neuron degeneration in a model of coenzyme Q deficiency
  770. Cellular mechanisms affecting Alzheimer’s amyloid-beta aggregation in Saccharomyces cerevisiae
  771. Clinical disorders of membrane transport processes
  772. Department of Pharmacology and Cancer Biology
  773. Soft tissue injury
  774. Immune Dysfunction in the Ts65Dn mouse model of Down Syndrome: Potential Role (s) of Reactive Oxygen Species (ROS) and Alterations in IL-7Rα Expression
  775. Investigating the relationship between sleep disordered breathing, glycaemic control and inflammation
  776. Interaction of Poly (ADP-ribose) and Specific Binding Proteins as a Function of Chain Length
  777. The Wine and Food Lover’s Diet: 28 Days of Delicious Weight Loss
  778. The differential Role of Insulin-like Growth Factor-1 Isoforms in Skeletal muscle
  779. An investigation of psychological stress, coping styles/strategies and psychological adjustments in a sample of Indian South African women with breast cancer in …
  780. Abstract VIII Congresso Nazionale Sindem 2013
  781. Heterochromatin effects in Friedreich’s ataxia and sexual dimorphism
  782. Function of human retinol dehydrogenase 12 (RDH12) in retinoid metabolism
  783. Evaluation of the effect of morphological control of dimorphic Mucor circinelloides on heterologous enzyme production
  784. The creation health breakthrough: 8 essentials to revolutionize your health physically, mentally, and spiritually
  785. Mechanisms of lifespan extension in yeast
  786. The role of calcium in light-induced photoreceptor apoptosis
  787. Exercise attenuates the major hallmarks of AGING
  788. Long noncoding RNAs (lncRNAs) and the molecular hallmarks of AGING
  789. Rheumatoid arthritis, immunosenescence and the hallmarks of AGING
  790. Calorie restriction and NAD+/sirtuin counteract the hallmarks of AGING
  791. Redox theory of AGING
  792. Neuropeptide Y: an anti-AGING player?
  793. A platform for rapid exploration of AGING and diseases in a naturally short-lived vertebrate
  794. Motor AGING results from cerebellar neuron death
  795. Blue journal conference. AGING and susceptibility to lung disease
  796. Regulatory roles of miRNAs in AGING
  797. Hemodynamic AGING as the consequence of structural changes associated with early vascular AGING (EVA)
  798. Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-AGING effect
  799. Chondrosenescence: definition, hallmarks and potential role in the pathogenesis of osteoarthritis
  800. Reply to Newman: quantification of biological AGING in young adults is not the same thing as the onset of obesity
  801. Rheumatoid arthritis, immunosenescence and the hallmarks of AGING
  802. Epigenetics of hematopoietic stem cell AGING and disease
  803. Common features of chromatin in AGING and cancer: cause or coincidence?
  804. Prelamin A and Oct-1: a puzzle of AGING
  805. The zebrafish as a gerontology model in nervous system AGING, disease, and repair
  806. The effect of AGING on neuroregenerative capacities
  807. Commentary: What is AGING? Can it be Eliminated?
  808. Stem cell depletion by global disorganization of the H3K9me3 epigenetic marker in AGING
  809. Hydra, a powerful model for AGING studies
  810. Stress biology and AGING mechanisms: toward understanding the deep connection between adaptation to stress and longevity
  811. AGING and Cancer: a Long-Term Relationship
  812. Enhanced proteasome degradation extends Caenorhabditis elegans lifespan and alleviates aggregation-related pathologies
  813. SIRT3 regulates progression and development of diseases of AGING
  814. The mechanistic links between proteasome activity, AGING and agerelated diseases
  815. Smoking accelerates AGING of the small airway epithelium
  816. Molecular mechanisms of normal and pathological AGING
  817. Can AGING be reversed?
  818. Integration-free mRNA reprogramming of human fibroblasts: The study of AGING upon reprogramming
  819. The effect of AGING on neuroregenerative capacities: insights from the senescent zebrafish retina
  820. Revealing the pathogenic and AGING-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model
  821. The impact of AGING on the regenerative potential of the zebrafish
  822. The master switchers in the AGING of cardiovascular system, reverse senescence by microRNA signatures; as highly conserved molecules
  823. Proteome-wide analysis of in situ aged fibroblasts
  824. The effect of AGING on neuroregenerative capacities: insights from the senescent zebrafish
  825. Cellular senescence affects neuroregenerative capacities in the aged zebrafish retinotectal system
  826. Ontology of AGING
  827. Current research in AGING: a report from the 2015 Ageing Summit
  828. Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts
  829. Impact of the circadian clock on the AGING process
  830. Significance of metallothioneins in AGING brain
  831. Cheating death: does the new biology of AGING show us the way?
  832. AGING‐Related Changes in Inflammatory and LKB1/AMPK Gene Expression in Fibromyalgia Patients
  833. Perspectives on Communication and AGING
  834. Journal of AGING Science
  835. A New, Discontinuous 2 Phases of AGING Model: Lessons from Drosophila melanogaster
  836. AGING and DNA methylation
  837. The African turquoise killifish: a model for exploring vertebrate AGING and diseases in the fast lane
  838. The mechanobiology of AGING
  839. The role of mitochondrial dysfunction in age-related diseases
  840. New malaria drug unleashes an immune system assault on infected cells
  841. Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence
  842. Beyond audibility–the role of supra-threshold auditory processing and cognition in presbycusis
  843. p16INK4a, NAD+, and Sestrins: New Targets for Combating AGING‐Related Chronic Illness?
  844. Promoting healthy brain AGING
  845. Task-dependent activity and connectivity predict episodic memory network-based responses to brain stimulation in healthy AGING
  846. Programming and reprogramming cellular age in the era of induced pluripotency
  847. The critical need to promote research of AGING and AGING-related diseases to improve health and longevity of the elderly population
  848. MitomiRs in human inflamm-AGING: a hypothesis involving miR-181a, miR-34a and miR-146a
  849. The cell biology of AGING
  850. Can AGING be’drugged’?
  851. AGING and lung disease. Clinical impact and cellular and molecular pathways
  852. Somatic expression of unc-54 and vha-6 mRNAs declines but not pan-neuronal rgef-1 and unc-119 expression in AGING Caenorhabditis elegans
  853. Why adult stem cell functionality declines with age? Studies from the fruit fly Drosophila melanogaster model organism
  854. Systemic sclerosis-associated fibrosis: an accelerated AGING phenotype?
  855. MicroRNAs as mediators of the ageing process
  856. Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer
  857. Invertebrates as model organisms for research on AGING biology
  858. Microglial dysfunction in brain AGING and Alzheimer’s disease
  859. Epigenetics of AGING
  860. A new 2-phases model of AGING that fits to different organisms
  861. Age-related diseases: common or diverse pathways?
  862. Evidence for Premature AGING of (Clonal but also) Non-Clonal Hematopoietic Stem Cells in Patients with Acute Myeloid Leukemia (AML)
  863. iPSCs as a major opportunity to understand and cure age-related diseases
  864. Hypertension, aortic valve stenosis, and the aorta: more lessons from TAVR
  865. Epigenetics of AGING and AGING-related disease
  866. Impact of nutrition on the ageing process
  867. Impact of bacterial infections on AGING and cancer: impairment of DNA repair and mitochondrial function of host cells
  868. The yeast polo kinase Cdc5 regulates the shape of the mitotic nucleus
  869. Mitochondrial and ubiquitin proteasome system dysfunction in ageing and disease: two sides of the same coin?
  870. Intervening in ageing to prevent the diseases of ageing
  871. Accelerating AGING research: how can we measure the rate of biologic AGING?
  872. A human experimental model of laminopathy based on adult stem cells establishes the relevance of Oct1 transcription factor in the AGING process
  873. Age-Related Changes to Drosophila m. Male Germline Stem Cells
  874. The role of macromolecular damage in AGING and age-related disease
  875. Towards an evidence-based model of AGING
  876. Antioxidant potential of phycobiliproteins: Role in anti-AGING research
  877. Silver oncologic tsunami: quality issues in the senior adult oncology population
  878. Translational research on AGING: clinical epidemiology as a bridge between the sciences
  879. An emerging interplay between altered human lipid metabolism, lipodystrophy and AGING
  880. Proteasome function is not impaired in healthy AGING of the lung
  881. Telomere dynamics and AGING
  882. Modelizing Drosophila melanogaster longevity curves using a new discontinuous 2-Phases of AGING model
  883. Biological effects induced by specific advanced glycation end products in the reconstructed skin model of AGING
  884. Proteome-wide analysis of primary cultures of in situ aged human fibroblasts reveals a moderate age-associated cellular phenotype
  885. Biologic AGING, frailty, and age-related disease in chronic HIV infection
  886. Geroscience: linking AGING to chronic disease
  887. Age and cancer risk: a potentially modifiable relationship
  888. Defining the general principles of stem cell AGING: lessons from organismal models
  889. Genomics of Lung AGING and Idiopathic Pulmonary Fibrosis
  890. Frailty in AGING: Biological, Clinical and Social Implications
  891. Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively
  892. Endocannabinoid signalling and the deteriorating brain
  893. 2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of AGING …
  894. Premature AGING in chronic kidney disease and chronic obstructive pulmonary disease: similarities and differences
  895. DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’
  896. AGING-related inflammation in osteoarthritis
  897. Proteostasis and longevity: when does AGING really begin?
  898. The NR4A nuclear receptors as potential targets for anti-AGING interventions
  899. Meeting current musculoskeletal health demand through deeper insights into tissue homeostasis and regeneration
  900. AGING of the brain, dementias, role of infectious proteins: facts and theories
  901. Naive T cell maintenance and function in human AGING
  902. Frailty for surgeons: review of a national institute on AGING conference on frailty for specialists
  903. It is time to classify biological AGING as a disease
  904. A summary of the biological basis of frailty
  905. Frailty: scaling from cellular deficit accumulation?
  906. A stress-induced cellular AGING model with postnatal neural stem cells
  907. Muscle stem cell AGING: regulation and rejuvenation
  908. Oxidative stress, mitochondrial dysfunction and the mitochondria theory of AGING
  909. Wnt signaling and osteoporosis
  910. Somatic mutation in cancer and normal cells
  911. AGING and uremia: Is there cellular and molecular crossover?
  912. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell AGING
  913. AGING: not all DNA damage is equal
  914. AGING is not a disease: implications for intervention
  915. Fibrosis and renal AGING
  916. Host age is a systemic regulator of gene expression impacting cancer progression
  917. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner
  918. Stress and optimal ageing
  919. Sirtuin function in AGING heart and vessels
  920. The epigenetic tracks of AGING
  921. Computational Biology in Human AGING
  922. Near-infrared light increases ATP, extends lifespan and improves mobility in aged Drosophila melanogaster
  923. AGING: a common driver of chronic diseases and a target for novel interventions
  924. Why is AGING conserved and what can we do about it?
  925. Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of AGING and cancer
  926. Inhibition of PMCA activity by tau as a function of AGING and Alzheimer’s neuropathology
  927. Lipid profile and cytokines interactions during successful AGING
  928. The intricate interplay between mechanisms underlying AGING and cancer
  929. Impact of miRNAs on cardiovascular AGING
  930. Exploiting tumor cell senescence in anticancer therapy
  931. Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: a paradigm for axonal degeneration
  932. A novel method to study AGING in bacteria that reproduce by morphologically symmetric fission
  933. The interplay between mitochondria and autophagy and its role in the AGING process
  934. C108 AGING: THE COMMON DENOMINATOR: Hic-5/nox4 Signaling Regulates Proteostasis And Senescence
  935. Botryllus schlosseri, an emerging model for the study of AGING, stem cells, and mechanisms of regeneration
  936. Aged Chinese rhesus macaques suffer severe phenotypic T-and B-cell AGING accompanied with sex differences
  937. Determinants of frailty and longevity: are they the same ones?
  938. Cardiac AGING—getting to the stem of the problem
  939. The role of Pycr1 in the pathomechanism of autosomal recessive cutis laxa
  940. Changes in transcription and metabolism during the early stage of replicative cellular senescence in budding yeast
  941. Fibrosis: ultimate and proximate causes
  942. Maintenance of homeostasis in the AGING hypothalamus: the central and peripheral roles of succinate
  943. Epigenomic profiling of young and aged HSCs reveals concerted changes during AGING that reinforce self-renewal
  944. Accelerated AGING among cancer survivors: from pediatrics to geriatrics
  945. The theories of AGING: reactive oxygen species and what else
  946. Up-regulating telomerase and tumor suppressors: focusing on anti-AGING interventions at the population level
  947. AGING and liver disease
  948. AGING research—where do we stand and where are we going?
  949. DNA repair and AGING: the impact of the p53 family
  950. Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cell
  951. N-acetylmannosamine improves sleep–wake quality in middle-aged mice: Relevance to autonomic nervous function
  952. Resistance exercise and testosterone treatment alters the proportion of numerical density of capillaries of the left ventricle of AGING Wistar rats
  953. Non-lethal ionizing radiation promotes AGING-like phenotypic changes of human hematopoietic stem and progenitor cells in humanized mice
  954. TERT promoter mutations in cancer development
  955. AGING and blood disorders: new perspectives, new challenges
  956. The AGING kidney revisited: a systematic review
  957. Geroconversion: irreversible step to cellular senescence
  958. High-throughput analysis of yeast replicative AGING using a microfluidic system
  959. Efficacy of prophylactic flavan-3-ol in permanent focal ischemia in 12-mo-old mice
  960. Exome and whole genome sequencing in AGING and longevity
  961. Comprehensive transcriptional landscape of AGING mouse liver
  962. Role of noncoding RNAs in cardiovascular AGING
  963. Translating Gerontology into Practice
  964. AGING synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function
  965. Myc mouse and anti-ageing therapy
  966. The role of protein clearance mechanisms in organismal ageing and age-related diseases
  967. Human AGING in the post-GWAS era: further insights reveal potential regulatory variants
  968. Defining AGING in cyborgs: A bio-techno-social definition of AGING
  969. C108 AGING: THE COMMON DENOMINATOR: AGING In Idiopathic Pulmonary Fibrosis (ipf)-Nothing More Than A Risk Factor? Study On Mitochondrial Dysfunction …
  970. AGING is neither a failure nor an achievement of natural selection
  971. Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation
  972. Genetics and epigenetics of AGING and longevity
  973. Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats
  974. Submission PDF
  975. Molecular aspects of AGING: understanding lung AGING
  976. Isolating intestinal stem cells from adult Drosophila midguts by FACS to study stem cell behavior during AGING
  977. Natural compounds and AGING: between autophagy and inflammasome
  978. Proteostasis and AGING of stem cells
  979. The AGING-disease false dichotomy: understanding senescence as pathology
  980. Design of Novel Malar Implant With Dual Plane Adhesion
  981. TIME-DEPENDENT EFFECT OF TOCOTRIENOL SUPPLEMENTATION ON THE QUALITY OF AGING MOUSE EMBRYO
  982. L-lactate protects skin fibroblasts against AGING-associated mitochondrial dysfunction via mitohormesis
  983. AGING and Cell AGING: An Introduction
  984. Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain AGING–impact of Bcl-2 and NPD-1 like metabolites
  985. Autophagy: a druggable process that is deregulated in AGING and human disease
  986. Accelerated ageing of the lung in COPD: new concepts
  987. Can being ageist harm your older adult patients?
  988. DNA methylation age of blood predicts future onset of lung cancer in the women’s health initiative
  989. Frailty: a tale of two concepts
  990. Cardiovascular physiology in the older adults
  991. Reconsidering the role of mitochondria in AGING
  992. Genome sequencing fishes out longevity genes
  993. Males shorten the life span of C. elegans hermaphrodites via secreted compounds
  994. Genetics and pharmacology of longevity: the road to therapeutics for healthy AGING
  995. Mechanisms shaping the naïve T cell repertoire in the elderly—thymic involution or peripheral homeostatic proliferation?
  996. Current AGING research in China
  997. Shared signatures of social stress and AGING in peripheral blood mononuclear cell gene expression profiles
  998. Recurrent turnover of senescent cells during regeneration of a complex structure
  999. A chaperome subnetwork safeguards proteostasis in AGING and neurodegenerative disease
  1000. AGING and age-related diseases–from endocrine therapy to target therapy
  1001. Siglec receptors impact mammalian lifespan by modulating oxidative stress
  1002. Frailty and social vulnerability
  1003. The biology of AGING and lymphoma: a complex interplay
  1004. Revisiting an age-old question regarding oxidative stress
  1005. Mediation of organismal AGING and somatic proteostasis by the germline
  1006. Genes Revisited: The Biodemography of Social Environmental Variation Through a Functional Genomics Lens
  1007. miRNAs in lung cancer: a link to AGING
  1008. AGING and multimorbidity: new tasks, priorities, and frontiers for integrated gerontological and clinical research
  1009. Sick sinus syndrome: synopsis
  1010. A mitochondrially targeted compound delays AGING in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox …
  1011. AGING and malignant hemopathies
  1012. Telomere regulation in pluripotent stem cells
  1013. A conserved transcriptional signature of delayed AGING and reduced disease vulnerability is partially mediated by SIRT3
  1014. DNA repair defects and genome instability in Hutchinson–Gilford progeria syndrome
  1015. The need to promote AGING research
  1016. Network medicine, multimorbidity and the lung in the elderly
  1017. Regenerative medicine in the treatment of idiopathic pulmonary fibrosis: current position
  1018. From inflammAGING to healthy AGING by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
  1019. Polysaccharides from medicinal herbs as potential therapeutics for AGING and age-related neurodegeneration
  1020. Potential anti-AGING role of taurine via proper protein folding: a study from taurine transporter knockout mouse
  1021. DNA replication stress as a hallmark of cancer
  1022. Theories and mechanisms of AGING
  1023. Ageing as developmental decay: insights from p16INK4a
  1024. Classifying AGING as a disease in the context of ICD-11
  1025. WIPI-mediated autophagy and longevity
  1026. Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human …
  1027. Sirtuins: guardians of mammalian healthspan
  1028. Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition
  1029. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human AGING
  1030. The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4
  1031. Longevity sticker shock: The one remaining obstacle to widespread credentialed support for rejuvenation biotechnology
  1032. The role of AGING T-lymphocytes in prostate cancer development
  1033. Genomic profiling of type-1 adult diabetic and aged normoglycemic mouse liver
  1034. Emerging roles of frailty and inflammAGING in risk assessment of age-related chronic diseases in older adults: the intersection between AGING biology and …
  1035. Contemporary approaches to idiopathic pulmonary fibrosis
  1036. Response to the letter from Xue And Varadhan:” What is missing in the validation of frailty instruments?”.
  1037. Can enhanced autophagy be associated with human longevity? Serum levels of the autophagy biomarker beclin-1 are increased in healthy centenarians
  1038. Human telomere biology: a contributory and interactive factor in AGING, disease risks, and protection
  1039. FOXO transcription factors: key regulators of cellular quality control
  1040. Analytical approaches to the diagnosis and treatment of AGING and AGING-related disease: redox status and proteomics
  1041. Effects of extrinsic mortality on the evolution of AGING: a stochastic modeling approach
  1042. Cellular signaling in the AGING immune system
  1043. Shorter telomeres with high telomerase activity are associated with raised allostatic load and impoverished psychosocial resources
  1044. JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
  1045. Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast AGING
  1046. Questioning causal involvement of telomeres in AGING
  1047. Stem cells versus senescence: the yin and yang of cardiac health
  1048. The African turquoise killifish genome provides insights into evolution and genetic architecture of lifespan
  1049. A62 LUNG FIBROSIS: FIBROBLAST BIOLOGY: Fibroblasts From Ipf And From Lungs Of Old Mice Show Impaired Autophagy
  1050. High-throughput sequencing insights into T-cell receptor repertoire diversity in AGING
  1051. Worker senescence and the sociobiology of AGING in ants
  1052. Genética do envelhecimento e seu impacto sobre a longevidade humana: teorias e evidências para prevenção das doenças do envelhecimento
  1053. Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for AGING and cancer prevention: do we really have an antiAGING drug?
  1054. Concurrent purification and antioxidant activity of phycobiliproteins from Lyngbya sp. A09DM: An antioxidant and anti-AGING potential of phycoerythrin in …
  1055. Noncoding transcriptional landscape in human AGING
  1056. Closing the Circle: Stem Cell Rejuvenation and Longevity
  1057. Phycoerythrin extends life span and health span of Caenorhabditis elegans
  1058. Cellular and molecular mechanisms of negligible senescence: insight from the sea urchin
  1059. Adult stem cells and diseases of AGING
  1060. Impact of senescence on bone quality: lessons from animal models of AGING
  1061. Perinatal complications and AGING indicators by midlife
  1062. Cardiorespiratory capacity and leukocyte telomere length among adults in the United States
  1063. AGING and epigenetic drift: a vicious cycle
  1064. Oxidative stress in the AGING process: fundamental aspects and new insights
  1065. Select AGING biomarkers based on telomere length and chronological age to build a biological age equation
  1066. Physical activity, fitness, and gray matter volume
  1067. When anti-AGING studies meet cancer chemoprevention: can anti-AGING agent kill two birds with one blow?
  1068. MicroRNA expression altered by diet: can food be medicinal?
  1069. SIRT6: a promising target for cancer prevention and therapy
  1070. Antagonistic functions of LMNA isoforms in energy expenditure and lifespan
  1071. Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near …
  1072. Growth phase-dependent roles of Sir2 in oxidative stress resistance and chronological lifespan in yeast
  1073. Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development
  1074. Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling
  1075. Smoking and interstitial lung diseases
  1076. The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice
  1077. Cell Competition: Roles and Importance as a Central Phenomenon
  1078. Ageing and inflammation–a central role for mitochondria in brain health and disease
  1079. Cellular and molecular longevity pathways: the old and the new
  1080. Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts
  1081. Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients
  1082. Signaling pathway activation drift during AGING: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells
  1083. Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human …
  1084. Metabolomic analyses reveal that anti-AGING metabolites are depleted by palmitate but increased by oleate in vivo
  1085. The ageing process and healthy ageing
  1086. Stress and AGING at the nuclear gateway
  1087. Metabolic effects of caloric restriction
  1088. The inflammTORy powers of senescence
  1089. Effects of polychlorinated biphenyls (PCBs) on telomere maintenance in hematopoietic stem cells and progenitor cells
  1090. Palladium and platinum nanoparticles attenuate AGING-like skin atrophy via antioxidant activity in mice
  1091. On the apparent rarity of epithelial cancers in captive chimpanzees
  1092. Three-dimensional human facial morphologies as robust AGING markers
  1093. Using zebrafish models to explore genetic and epigenetic impacts on evolutionary developmental origins of AGING
  1094. MARK-AGE biomarkers of ageing
  1095. Exosomes and autophagy: coordinated mechanisms for the maintenance of cellular fitness
  1096. Promoter Polymorphism in the Serotonin Transporter (5-HTT) Gene Is Significantly Associated with Leukocyte Telomere Length in Han Chinese
  1097. Lung cancer: progress in diagnosis and treatments. Topics: III. Treatment; 7. Lung cancer treatment in elderly and/or high risk patients
  1098. Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the AGING process
  1099. Ending AIDS and challenges for Asia
  1100. Longevity extension by phytochemicals
  1101. Cell therapy strategies to combat immunosenescence
  1102. A proposed panel of biomarkers of healthy ageing
  1103. Role of microRNAs in the age-related changes in skeletal muscle and diet or exercise interventions to promote healthy AGING in humans
  1104. AGING and systemic lupus erythematosus-immunosenescence and beyond
  1105. New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses
  1106. Geriatric population and relevant contemplation
  1107. Complex Molecular Networks Promote Longevity
  1108. Effect on ATPase, succinate dehydrogenase and total antioxidant capacity in mice myocardium of fluorosis
  1109. Discovering novel microRNAs and age-related nonlinear changes in rat brains using deep sequencing
  1110. In Search for Anti-AGING Strategy: Can We Rejuvenate Our AGING Stem Cells?
  1111. Better to burn out than it is to rust: coordinating cellular redox states during AGING and stress
  1112. Alpha-synuclein levels in blood plasma decline with healthy AGING
  1113. Humulus japonicus extract exhibits antioxidative and anti‑AGING effects via modulation of the AMPK‑SIRT1 pathway
  1114. Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts
  1115. Towards truly interdisciplinary research on human development
  1116. 22.1 The AOP Concept in the Context of Risk Assessment Procedures
  1117. Nutrient status assessment in individuals and populations for healthy AGING—statement from an expert workshop
  1118. Electrical stimulation counteracts muscle decline in seniors
  1119. Hydrogen sulfide donor protects porcine oocytes against AGING and improves the developmental potential of aged porcine oocytes
  1120. Genetics and epigenetics of human retinoblastoma
  1121. Telomeres shorten more slowly in slow-AGING wild animals than in fast-AGING ones
  1122. Telomerase therapy to reverse cardiovascular senescence
  1123. Functional consequences of neurite orientation dispersion and density in humans across the adult lifespan
  1124. Management of elderly patients with chronic lymphocytic leukemia in the era of targeted therapies
  1125. Telomerase activation: a potential key modulator for human healthspan and longevity
  1126. Mechanisms underlying the anti-AGING and anti-tumor effects of lithocholic bile acid
  1127. Increased DNA methylation in the suicide brain
  1128. Is chronic asthma associated with shorter leukocyte telomere length at midlife?
  1129. polylactic acid Fillers
  1130. Role of asymmetric cell division in lifespan control in Saccharomyces cerevisiae
  1131. Comparing 26S Proteasome Efficiency Between Long-Living and Short-Living Rodents
  1132. Ageing neurons need REST
  1133. Metabolic dysfunction consistent with premature AGING results from deletion of Pim kinases
  1134. Skeletal muscle lipid content and oxidative activity in relation to muscle fiber type in AGING and metabolic syndrome
  1135. Tissue-specific ageing of rat tendon-derived progenitor cells
  1136. AGING mesenchymal stem cells fail to protect because of impaired migration and antiinflammatory response
  1137. Physical activity, physical fitness and leukocyte telomere length: the cardiovascular health study
  1138. Chronic obstructive pulmonary disease and cerebrovascular disease: a comprehensive review
  1139. Selective insulin resistance in hepatocyte senescence
  1140. The paradigm of mutant p53-expressing cancer stem cells and drug resistance
  1141. D-galactose induces a mitochondrial complex I deficiency in mouse skeletal muscle: potential benefits of nutrient combination in ameliorating muscle impairment
  1142. Hormetins as novel components of cosmeceuticals and AGING interventions
  1143. Pathogenesis of osteoporosis
  1144. Profiling of Sox4-dependent transcriptome in skin links tumour suppression and adult stem cell activation
  1145. Translational Research in the Fastest-Growing Population: Older Adults
  1146. DNA damage response and metabolic disease
  1147. The redox code
  1148. Serum copper to zinc ratio: Relationship with AGING and health status
  1149. REACTIVE OXYGEN SPECIES AND TELOMERE DYSFUNCTION: INVESTIGATING THE UNDERLYING MECHANISMS OF AGING AND RELATED DISEASES
  1150. Studying variability in human brain AGING in a population-based German cohort—rationale and design of 1000BRAINS
  1151. Essential role for autophagy in life span extension
  1152. Mechanisms of AGING: Neuronal Orchestration of Stress Resistance and Protein Homeostasis in the Nematode Caenorhabditis elegans
  1153. Breakdown of epithelial barrier integrity and overdrive activation of alveolar epithelial cells in the pathogenesis of acute respiratory distress syndrome and …
  1154. Measurement of mitochondrial NADH and FAD autofluorescence in live cells
  1155. Telomere length differences between subcutaneous and visceral adipose tissue in humans
  1156. New roles for mitochondrial proteases in health, ageing and disease
  1157. The Neural Progenitor Cell (NPC) Niche in the Adult Brain Provides a Target for Neurotoxicity: A Putative Adverse Outcome Pathway for ROS-Induced NPC …
  1158. Proteasome activation delays AGING in vitro and in vivo
  1159. Increase of oxidation and inflammation in nervous and immune systems with AGING and anxiety
  1160. Impact of age-related neuroglial cell responses on hippocampal deterioration
  1161. Mechanisms by which different functional states of mitochondria define yeast longevity
  1162. Standard laboratory tests to identify older adults at increased risk of death
  1163. Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allografts
  1164. How old is “too old” for translational research?
  1165. INFLUENCE OF GENETIC VARIATIONS IN PHYSICAL FITNESS
  1166. Acoustic and respiratory measures as a function of age in the male voice
  1167. The role of mitochondrial DNA mutation on neurodegenerative diseases
  1168. Decreases in daily physical activity predict acute decline in attention and executive function in heart failure
  1169. Association between maturation and AGING and pulmonary responses in animal models of lung injury: a systematic review
  1170. Alive and well? Exploring disease by studying lifespan
  1171. Ablation of the p16 INK4a tumour suppressor reverses ageing phenotypes of klotho mice
  1172. DNA damage-induced microRNA Let-7 influences both cancer and AGING-associated processes
  1173. Thioredoxin Reductase 2 (Txnrd2) Regulates Mitochondrial Integrity in the Progression of Age‐Related Heart Failure
  1174. Mice with pulmonary fibrosis driven by telomere dysfunction
  1175. Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome
  1176. New biological mechanisms and intervention strategies in AGING and cancer
  1177. Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies
  1178. The P5 disulfide switch: taming the AGING unfolded protein response
  1179. Nuclear matrix, nuclear envelope and premature AGING syndromes in a translational research perspective
  1180. Impact of phosphorus-based food additives on bone and mineral metabolism
  1181. UPRmt-mediated cytoprotection and organismal AGING
  1182. Cell ageing: a flourishing field for neurodegenerative diseases
  1183. Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases
  1184. Pharmacogenomic analysis indicates potential of 1, 5-isoquinolinediol as a universal anti-AGING agent for different tissues
  1185. Methylene blue promotes quiescence of rat neural progenitor cells
  1186. The impact of immunosenescence on pulmonary disease
  1187. Mediterranean diet and healthy ageing: a Sicilian perspective
  1188. When rejuvenation is a problem: challenges of modeling late-onset neurodegenerative disease
  1189. Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice
  1190. Stem cell AGING in adult progeria
  1191. Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder
  1192. Consequences of endogenous mitochondrial oxidative stress in the heart
  1193. How stem cells get “turned on”
  1194. Immunomodulatory role of high-density lipoproteins: impact on immunosenescence
  1195. Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious AGING
  1196. Changes in regenerative capacity through lifespan
  1197. Characterization of bone marrow-derived mesenchymal stem cells in AGING
  1198. Stem cell senescence as the memory of past injuries
  1199. Age-related obesity is a heritage of the evolutionary past
  1200. Transcriptomic and epigenetic analyses reveal a gender difference in AGING-associated inflammation: the Vitality 90+ study
  1201. The anti-AGING properties of a human placental hydrolysate combined with dieckol isolated from Ecklonia cava
  1202. Causes and consequences of age-related changes in DNA methylation: a role for ROS?
  1203. Genetic rejuvenation of old muscle
  1204. X chromosome aneuploidy in the Alzheimer’s disease brain
  1205. Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae
  1206. Aneuploidy: implications for protein homeostasis and disease
  1207. Age-related changes in resting energy expenditure in normal weight, overweight and obese men and women
  1208. Can mitochondrial dysfunction be a predictive factor for oxidative stress in patients with obstructive sleep apnea?
  1209. Effects of vitamin E on cognitive performance during ageing and in Alzheimer’s disease
  1210. Uncovering the geroprotective potential of medicinal plants from the Judea region of Israel
  1211. Histone methylation and AGING: lessons learned from model systems
  1212. Selected age-related disorders
  1213. The effects of age and latent cytomegalovirus infection on NK-cell phenotype and exercise responsiveness in man
  1214. The pathological role of adipose tissue AGING in the progression of systemic insulin resistance
  1215. DNA Damage and Checkpoint Responses in Adult Stem Cells
  1216. Tipping the metabolic scales towards increased longevity in mammals
  1217. Lipid replacement therapy: a natural medicine approach to replacing damaged lipids in cellular membranes and organelles and restoring function
  1218. From inflammAGING to healthy AGING by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
  1219. In vivo imAGING of mitophagy in Caenorhabditis elegans
  1220. Cholesterol and ocular pathologies: focus on the role of cholesterol-24S-hydroxylase in cholesterol homeostasis
  1221. Characterization of novel markers of senescence and their prognostic potential in cancer
  1222. Epigenetic modifiers of islet function and mass
  1223. Genome-wide gene expression in relation to age in large laboratory cohorts of Drosophila melanogaster
  1224. Candidate genes that affect AGING through protein homeostasis
  1225. AntiAGING phenotype in skeletal muscle after endurance exercise is associated with the oxidative phosphorylation pathway
  1226. Effects of donor age and proliferative AGING on the phenotype stability of rat aortic smooth muscle cells
  1227. The Biology of AGING: Role in Cancer, Metabolic Dysfunction, and Health Disparities
  1228. Expression of virus-responsive genes and their response to challenge with poly (I: C) at different stages of the annual fish Nothobranchius guentheri: Implications for …
  1229. Basic mechanisms of longevity: A case study of Drosophila pro-longevity genes
  1230. Longevity of U cells of differentiated yeast colonies grown on respiratory medium depends on active glycolysis
  1231. Hypothesis on skeletal muscle AGING: mitochondrial adenine nucleotide translocator decreases reactive oxygen species production while preserving coupling …
  1232. Spermidine induces autophagy by inhibiting the acetyltransferase EP300
  1233. Epigenomic programing: a future way to health?
  1234. Replicating through telomeres: a means to an end
  1235. Ujarzmianie starzenia: odm³adzanie komórek, dedyferencjacja i transdyferencjacja AGING subjugation: cell rejuvenation, dedifferentiation and …
  1236. Expression alterations define unique molecular characteristics of spinal ependymomas
  1237. Unmasking the lung cancer epigenome
  1238. Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing
  1239. Modeling signaling networks to advance new cancer therapies
  1240. Chromatin methylation and cardiovascular AGING
  1241. Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats
  1242. Cellular mechanisms of age-related hearing loss
  1243. Epigenetic mechanisms of dietary restriction induced AGING in Drosophila
  1244. Mitochondrial AGING and physical decline: insights from three generations of women
  1245. Response to the Letter to the Editor:“Frailty Consensus: A Call to Action”
  1246. CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?
  1247. Comorbid influences on generic health-related quality of life in COPD: a systematic review
  1248. A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma
  1249. Pushing the limits: defeating leukemia stem cells by depleting telomerase
  1250. New genetic and epigenetic approaches in gerontology
  1251. Age-associated methylation suppresses SPRY1, leading to a failure of re-quiescence and loss of the reserve stem cell pool in elderly muscle
  1252. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
  1253. Insights into the evolution of longevity from the bowhead whale genome
  1254. A stitch in time: the needlework of AGING women in antebellum America
  1255. NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats
  1256. The impact of MAO-A in cellular senescence
  1257. Pathological role of adipose tissue dysfunction in cardio-metabolic disorders
  1258. Positive psychological functioning and the biology of health
  1259. New insights into skin stem cell AGING and cancer
  1260. Cellular senescence in type 2 diabetes: a therapeutic opportunity
  1261. Human stem cell models of dementia
  1262. Colorectal cancer surgery remains effective with rising patient age
  1263. Movement-based behaviors and leukocyte telomere length among US adults
  1264. Gene expression in the liver of female, but not male mice treated with rapamycin resembles changes observed under dietary restriction
  1265. Cognitive frailty, a novel target for the prevention of elderly dependency
  1266. High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice
  1267. Synthetic lethal vulnerabilities of cancer
  1268. Early molecular changes in Alzheimer disease: can we catch the disease in its presymptomatic phase?
  1269. Hutchinson–Gilford progeria syndrome
  1270. AGING and cardiovascular diseases: The role of gene–diet interactions
  1271. Peroxisome proliferator–activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP‐activated protein kinase
  1272. Falls in older adults with cancer
  1273. Herpes simplex virus shedding: Biomarker for disease severity and response to antivirals
  1274. Profiling Molecular Changes to Discover New Drivers of AGING in C. Elegans
  1275. Emerging clinical issues related to management of multiorgan comorbidities and polypharmacy
  1276. A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan
  1277. Proteasome-mediated quality control of S-nitrosylated mitochondrial proteins
  1278. Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome
  1279. Gender-and region-dependent changes of redox biomarkers in the brain of successfully AGING LOU/C rats
  1280. Telomere dysfunction in peripheral blood mononuclear cells from patients with primary biliary cirrhosis
  1281. 20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans
  1282. Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human AGING
  1283. Role of cigarette smoke–induced aggresome formation in chronic obstructive pulmonary disease–emphysema pathogenesis
  1284. Jonathan A. Brassard, Natalie Fekete
  1285. Superoxide dismutase 1 loss disturbs intracellular redox signaling, resulting in global age-related pathological changes
  1286. Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians
  1287. ImAGING of cellular AGING in human retinal blood vessels
  1288. Epigenetic Adaptation to Mitochondrial Stress
  1289. The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
  1290. Mitochondria in health, AGING and diseases: the epigenetic perspective
  1291. Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo
  1292. Protective Effects of Unacylated Ghrelin in AGING Mice
  1293. Wnt4 signaling prevents skeletal AGING and inflammation by inhibiting nuclear factor-κB
  1294. GENERAL INTRODUCTION & OUTLINE OF THE THESIS
  1295. The Ras-Erk-ETS-signaling pathway is a drug target for longevity
  1296. Dietary restriction improves vasomotor changes caused by accelerated vascular AGING due to genomic instability
  1297. Inhibition of JAK-STAT signaling stimulates adult satellite cell function
  1298. Asthma in the Elderly
  1299. Cellular mechanisms of somatic stem cell AGING
  1300. Longevity pathways (mTOR, SIRT, Insulin/IGF-1) as key modulatory targets on AGING and neurodegeneration
  1301. Periplasmic Acid Stress Increases Cell Division Asymmetry (Polar AGING) of Escherichia coli
  1302. DDR-mediated crosstalk between DNA-damaged cells and their microenvironment
  1303. Protein profiling reveals consequences of lifestyle choices on predicted biological AGING
  1304. Cholest erol alimentaire, ami ou ennemi?
  1305. Rejuvenation of the muscle stem cell population restores strength to injured aged muscles
  1306. Ginsenoside Rg1 enhances the resistance of hematopoietic stem/progenitor cells to radiation-induced AGING in mice
  1307. Decline of phosphotransfer and substrate supply metabolic circuits hinders ATP cycling in AGING myocardium
  1308. SKN-1/Nrf, stress responses, and AGING in Caenorhabditis elegans
  1309. Rifampicin reduces advanced glycation end products and activates DAF‐16 to increase lifespan in Caenorhabditis elegans
  1310. Prostaglandins, Leukotrienes and Essential Fatty Acids
  1311. Transcription errors induce proteotoxic stress and shorten cellular lifespan
  1312. Telomerase Activity and Telomere Length in Daphnia
  1313. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-AGING miRNA expression profile in …
  1314. Walking and psychomotor speed in the elderly: concordance, correlates and prediction of death
  1315. A prospective epigenetic paradigm between cellular senescence and epithelial-mesenchymal transition in organismal development and AGING
  1316. Ageing and the border between health and disease
  1317. Measuring in vivo mitophagy
  1318. Mechanisms and functions of Nrf2 signaling in Drosophila
  1319. Elimination of unfit cells maintains tissue health and prolongs lifespan
  1320. Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients
  1321. AGING Lung, Environmental and Genetic Factors—Race, Ethnicity and Gender
  1322. Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains
  1323. Protein aggregates are associated with replicative AGING without compromising protein quality control
  1324. Multisystem physiologic impairments and changes in gait speed of older adults
  1325. Effects of a DVD-delivered exercise intervention on physical function in older adults with multiple sclerosis: A pilot randomized controlled trial
  1326. AGING in Caenorhabditis elegans; the role of Wnt signalling
  1327. Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity
  1328. Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells
  1329. Neural Effects of Cognitive Intervention in Healthy AGING and Dementia
  1330. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency
  1331. Targeting mitochondrial energy metabolism with TSPO ligands
  1332. Essay: Intervening in the mTOR pathway: a promising anti-ageing therapy for humans?
  1333. The influence of AGING on oocyte quality and the importance of mitochondria
  1334. Involvement of oxysterols in age-related diseases and ageing processes
  1335. Mitochondrial oxidative stress, mitochondrial DNA damage and their role in age-related vascular dysfunction
  1336. Cellular Longevity of Budding Yeast During Replicative and Chronological AGING
  1337. Subjective beliefs, memory and functional health: Change and associations over 12 years in the Australian Longitudinal Study of Ageing
  1338. Biomedical Research
  1339. An evidence-based approach to identify AGING-related genes in Caenorhabditis elegans
  1340. Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise
  1341. Muscle wasting in myotonic dystrophies: a model of premature AGING
  1342. Bioactive silica nanoparticles reverse age-associated bone loss in mice
  1343. ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity
  1344. Stem cell factor is a novel independent prognostic biomarker for hepatocellular carcinoma after curative resection
  1345. Understanding and reducing disability in older adults following critical illness
  1346. Regenerative biology of tendon: mechanisms for renewal and repair
  1347. Investigating the regulation of stem and progenitor cell mitotic progression by in situ imAGING
  1348. iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis
  1349. DNA damages and premature AGING
  1350. Inflammation and intracellular metabolism: new targets in OA
  1351. Functional and molecular changes of MSCs in AGING
  1352. Systems biology and Systems medicine: The technological tools of the system approaches to complexity
  1353. Circadian rhythmicity as a predictor of weight-loss effectiveness
  1354. Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction
  1355. Identifying Micrornas that Regulate AGING of the Germline Stem Cell Niche
  1356. A critical role of Fas-associated protein with death domain phosphorylation in intracellular reactive oxygen species homeostasis and AGING
  1357. The amazing ubiquitin-proteasome system: structural components and implication in AGING
  1358. Compositional and functional features of the gastrointestinal microbiome and their effects on human health
  1359. Possible role of ABO system in age-related diseases and longevity: a narrative review
  1360. NAD+ metabolism in age-related hearing loss
  1361. Epigenome rejuvenation: HP1β mobility as a measure of pluripotent and senescent chromatin ground states
  1362. The GSK-3 family as therapeutic target for myocardial diseases
  1363. Identification of ageing-associated naturally occurring peptides in human urine
  1364. Reversal of hepatocyte senescence after continuous in vivo cell proliferation
  1365. Micronucleus frequency in peripheral blood lymphocytes and frailty status in elderly. A lack of association with clinical features
  1366. Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut
  1367. Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import
  1368. Establishing the microcrustacean Daphnia as a model system for research on AGING
  1369. AntiAGING effects of an intensive mind and body therapeutic program through enhancement of telomerase activity and adult stem cell counts
  1370. The role of mitochondrial DNA in mediating alveolar epithelial cell apoptosis and pulmonary fibrosis
  1371. Interaction between microRNA expression and classical risk factors in the risk of coronary heart disease
  1372. Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity
  1373. The fine line between lifespan extension and shortening in response to caloric restriction
  1374. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H 2 O 2 accumulation
  1375. Non-coding RNAs in cardiovascular ageing
  1376. Neurodegeneration in accelerated AGING
  1377. Vitellogenin family gene expression does not increase Drosophila lifespan or fecundity
  1378. Proteome analysis in the assessment of ageing
  1379. Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion
  1380. GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases
  1381. Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis
  1382. Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity
  1383. Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort
  1384. Emerging targets in osteoarthritis therapy
  1385. Modulation of a specific pattern of microRNAs, including miR-29a, miR-30a and miR-34a, in cultured human skin fibroblasts, in response to the application of …
  1386. Acoustic and respiratory measures as a function of age in the male voice
  1387. Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice
  1388. To unite or divide: mitochondrial dynamics in the murine outer retina that preceded age related photoreceptor loss
  1389. Global reorganization of the nuclear landscape in senescent cells
  1390. SIRT1: role in cardiovascular biology
  1391. MicroRNAs as potential targets for progressive pulmonary fibrosis
  1392. Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation
  1393. Fluorescence and bioluminescence imAGING of subcellular Ca2+ in aged hippocampal neurons
  1394. The functional and pathologic relevance of autophagy proteases
  1395. Amelioration of reproduction-associated oxidative stress in a viviparous insect is critical to prevent reproductive senescence
  1396. Mechanisms of development of multimorbidity in the elderly
  1397. Persistent γH2AX: A promising molecular marker of DNA damage and AGING
  1398. AGING without Apolipoprotein D: Molecular and cellular modifications in the hippocampus and cortex
  1399. Protective role of melatonin in mitochondrial dysfunction and related disorders
  1400. Farnesol-like endogenous sesquiterpenoids in vertebrates: the probable but overlooked functional “inbrome” anti-AGING counterpart of juvenile hormone of …
  1401. The crossroads between cancer stem cells and AGING
  1402. Essential roles of intracellular calcium release channels in muscle, brain, metabolism, and AGING
  1403. Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis
  1404. Suppression of Cellular Senescence by Cordycepin in Replicative Aged Human Dermal Fibroblasts
  1405. AGING of cell communication: loss of receptor function
  1406. Liver sinusoidal endothelial cells in hepatic fibrosis
  1407. Distinct metabolomic signatures are associated with longevity in humans
  1408. Pyridine nucleotides in regulation of cell death and survival by redox and non-redox reactions
  1409. Telomere shortening: a diagnostic tool and therapeutic target for cardiovascular disease?
  1410. Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression
  1411. Mining the modular structure of protein interaction networks
  1412. Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
  1413. DNA Damage and Checkpoint Responses in Adult Stem Cells
  1414. Caloric restriction mimetics: towards a molecular definition
  1415. Muscle weakness during AGING: a deficiency state involving declining angiogenesis
  1416. Chronic Asthma and Leukocyte Telomere Length
  1417. Trehalose accumulation triggers autophagy during plant desiccation
  1418. The retrotransposon Ty1 extends chronological lifespan in Saccharomyces paradoxus by influencing cellular responses to stress
  1419. Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis
  1420. Targeting mitochondria with small molecules: the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide
  1421. Is amyloid-β an innocent bystander and marker in Alzheimer’s disease? Is the liability of multivalent cation homeostasis and its influence on amyloid-β function the real …
  1422. The age related markers lipofuscin and apoptosis show different genetic architecture by QTL mapping in short-lived Nothobranchius fish
  1423. The aggregation and inheritance of damaged proteins determines cell fate during mitosis
  1424. The role of telomeres and vitamin D in cellular AGING and age-related diseases
  1425. ShaPINg cell fate upon DNA damage: role of Pin1 isomerase in DNA damage-induced cell death and repair
  1426. Whole-genome fingerprint of the DNA methylome during human B cell differentiation
  1427. Association between Longitudinally Assessed Dietary Composition and Blood Telomere Length among Young Adult Filipinos
  1428. Evidence-based medicine in older patients: how can we do better
  1429. Chromothripsis and Epigenetics, Important Mechanisms for Transgenerational Inheritance of Environmental History, Congenital Malformations and …
  1430. Quality control of oxidatively damaged mitochondrial proteins is mediated by p97 and the proteasome
  1431. HIV infection worsens age-associated defects in antibody responses to influenza vaccine
  1432. The effect of genomic instability on responsiveness to angiotensin II type 1 receptor stimulation and blockade
  1433. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition
  1434. Mitochondria, muscle health, and exercise with advancing age
  1435. The effect of coenzyme Q10 on age-related changes of the distal colon mucosa of male albino rats: a histological and immunohistochemical study
  1436. Understanding leukemic hematopoiesis as a complex adaptive system
  1437. Enhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade
  1438. Molecular mechanisms of dietary restriction in AGING—insights from Caenorhabditis elegans research
  1439. Accumulation Of Subcortical Iron As A Modifier Of Volumetric And Cognitive Decline In Healthy AGING: Two Longitudinal Studies
  1440. Nutritional approaches for healthy AGING of the brain and the prevention of neurodegenerative diseases
  1441. Repair of endogenous DNA base lesions modulate lifespan in mice
  1442. The role of extracellular vesicles: an epigenetic view of the cancer microenvironment
  1443. Pathogenesis and Susceptibility to Injury
  1444. Proteostasis in pediatric pulmonary pathology
  1445. Multifocal epithelial tumors and field cancerization: stroma as a primary determinant
  1446. Long-term omega-3 fatty acid supplementation prevents expression changes in cochlear homocysteine metabolism and ameliorates progressive hearing loss …
  1447. Amelioration of Reproduction-Associated Oxidative Stress in a Viviparous Insect Is
  1448. Clinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma
  1449. PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis
  1450. Resveratrol: a focus on several neurodegenerative diseases
  1451. Evidence-based medicine: blepharoplasty
  1452. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
  1453. Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury
  1454. Analysis of lifespan-promoting effect of garlic extract by an integrated metabolo-proteomics approach
  1455. Food preferences of elderly people of Mohodi Ga Manthata village in Limpopo Province, South Africa.
  1456. The role of microRNAs in mitochondria: small players acting wide
  1457. The senescence-associated secretory phenotype promotes benign prostatic hyperplasia
  1458. Targeting Mitochondria for Healthy Brain AGING
  1459. Alterations in gene array patterns in dendritic cells from aged humans
  1460. Autophagy and apoptosis in liver injury
  1461. Xianghong Yan1, Catherine Serre2, Laurine Bergeron2, Ludivine Mur2, Valère Busuttil2
  1462. Sox4 links tumor suppression to accelerated AGING in mice by modulating stem cell activation
  1463. Protein Biogenesis Machinery is a Driver of Replicative 4 AGING in Yeast 5
  1464. CINcere Modelling: What Have Mouse
  1465. IGF-1 colocalizes with muscle satellite cells following acute exercise in humans
  1466. Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation
  1467. Mitochondrial respiration controls lysosomal function during inflammatory T cell responses
  1468. mTOR, AMPK, and Sirt1: key players in metabolic stress management
  1469. Emerging regulators of the inflammatory process in osteoarthritis
  1470. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
  1471. The insulin-like growth factor system in the long-lived naked mole-rat
  1472. Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner
  1473. Chitinase but N-acetyl-β-D-glucosaminidase production correlates to the biomass decline in Penicillium and Aspergillus species
  1474. RTEL1: functions of a disease-associated helicase
  1475. Transient overexpression of Werner protein rescues starvation induced autophagy in Werner syndrome cells
  1476. A co-translational ubiquitination pathway for quality control of newly synthesized proteins
  1477. Integrative analysis of age-related changes in the transcriptome of Caenorhabditis elegans
  1478. Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera)
  1479. Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer’s disease.
  1480. Higher Alu methylation levels in catch-up growth in twenty-year-old offsprings
  1481. Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
  1482. Spartan deficiency causes genomic instability and progeroid phenotypes
  1483. The MRE11 complex and ATM activate distinct signaling responses to defend against DNA viruses versus DNA breaks
  1484. Epigenetics in liver disease
  1485. Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations
  1486. AGING, disease, and longevity in mice
  1487. Cross-sectional relations of arterial stiffness, pressure pulsatility, wave reflection, and arterial calcification
  1488. Uncoupling reproduction from metabolism extends chronological lifespan in yeast
  1489. Strengthening the role of convergence science in medicine
  1490. Autophagy and cellular senescence in lung diseases
  1491. Healthy AGING: Focus on the elderly people living at home with cardiovascular disease
  1492. Mitochondrial Priming and Anti-Apoptotic Dependencies in AGING and Diseased Bone Marrow
  1493. c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells
  1494. Subcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium
  1495. Inside and out: the activities of senescence in cancer
  1496. Genetic Regulation of Health Beneficial Phytonutrients in Fresh Produce
  1497. Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells
  1498. Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease
  1499. Skeletal muscle degeneration and regeneration in mice and flies
  1500. Self-consumption: the interplay of autophagy and apoptosis
  1501. Identification of potential mitochondrial CLPXP protease interactors and substrates suggests its central role in energy metabolism
  1502. MicroRNAs expression profiles in cardiovascular diseases
  1503. Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro
  1504. Idiopathic Pulmonary Fibrosis: Clinical Behavior, Pathogenic Mechanisms and Therapeutic Approach
  1505. Effects of sex steroids on bones and muscles: Similarities, parallels, and putative interactions in health and disease
  1506. Senescence-Associated Secretory Phenotype (SASP) involvement in the development of cancer, AGING and age related diseases
  1507. Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease
  1508. General introduction: The PKB/FOXO switch in ageing and cancer
  1509. Vascular and glial alterations during AGING in wild-type mice and along Alzheimer’s disease progression in APP/PS1 mice
  1510. Protein clearance mechanisms and their demise in age-related neurodegenerative diseases
  1511. Dissection of the cord blood stromal component reveals predictive parameters for culture outcome
  1512. Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence
  1513. Chitinase but N-acetyl-ß-D-glucosaminidase production correlates to the biomass decline in Penicillium and Aspergillus species
  1514. Assembly of Slx4 signaling complexes behind DNA replication forks
  1515. NK cells are activated in amnestic mild cognitive impairment but not in mild Alzheimer’s disease patients
  1516. Homology modeling, Molecular Dynamic Simulation and in silico screening of Activator for the Intensification of human sirtuin type 1 (SIRT1) by novel 1, 3, 4 …
  1517. The Impact of Immunosenescence on Pulmonary
  1518. NF-κB activation impairs somatic cell reprogramming in ageing
  1519. Protective effects of melatonin and mitochondria-targeted antioxidants against oxidative stress: a review
  1520. Nutrition in Older Adults Topic 36
  1521. Quantification of cellular viability by automated microscopy and flow cytometry
  1522. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells
  1523. Why is Qi-invigorating therapy in Chinese medicine suitable for mitochondrial diseases? A bioenergetic perspective
  1524. Autophagy in the hypothalamus: role of Neuropeptide Y and impact on Synaptic Plasticity
  1525. Multitasking Roles for Poly (ADP-ribosyl) ation in AGING and Longevity
  1526. 20S proteasome activation promotes life span extension and resistance to proteotoxicity in
  1527. Of mice, pigs and humans: an analysis of mitochondrial phospholipids from mammals with very different maximal lifespans
  1528. An automated phenotype-based microscopy screen to identify pro-longevity interventions acting through mitochondria in C. elegans
  1529. Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability
  1530. Role of macrophage migration inhibitory factor in age-related lung disease
  1531. Regulation of autophagy by cytosolic acetyl-coenzyme A
  1532. Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction.
  1533. Autophagic activity as an indicator for selecting good quality embryos
  1534. The renin–angiotensin system and its involvement in vascular disease
  1535. Disturbed flow promotes endothelial senescence via a p53-dependent pathway
  1536. Haptoglobin increases with age in rat hippocampus and modulates Apolipoprotein E mediated cholesterol trafficking in neuroblastoma cell lines
  1537. Clinical advances in geriatric psychiatry: a focus on prevention of mood and cognitive disorders
  1538. Long-term quiescent fibroblast cells transit into senescence
  1539. Loss of MT 1‐MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid
  1540. Activins: more than reproductive hormones
  1541. The impact of age and sex in DLBCL: systems biology analyses identify distinct molecular changes and signaling networks
  1542. Weaning triggers a maturation step of pancreatic β cells
  1543. Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation
  1544. Word count: 6352 (without Refs) References: 127
  1545. The disruption of proteostasis in neurodegenerative disorders
  1546. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts
  1547. Rebels with a cause: molecular features and physiological consequences of yeast prions
  1548. Excess costs of comorbidities in chronic obstructive pulmonary disease: a systematic review
  1549. A resourceful genome: updating the functional repertoire and evolutionary role of animal mitochondrial DNAs
  1550. Replicating through telomeres: a means to an end.
  1551. O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity
  1552. The Influence of the Insulin-Like Gene Family and Diet-Drug Interactions on Caenorhabditis elegans Physiology: A Dissertation
  1553. Variation in transcriptome size: are we getting the message?
  1554. Non-canonical Wnt4 prevents skeletal AGING and inflammation by inhibiting NF-κB
  1555. The systemic milieu as a mediator of dietary influence on stem cell function during ageing
  1556. Drug synergy drives conserved pathways to increase fission yeast lifespan
  1557. Recent developments in cardiovascular stem cells
  1558. American association for cancer research—AACR congress 2014
  1559. An endocrine genetic signal between blood cells and vascular smooth muscle cells: role of microRNA-223 in smooth muscle function and atherogenesis
  1560. Hematopoietic Stem and Progenitor Cell Function in Rheumatoid Arthritis
  1561. Sequential logic of polarity determination during the haploid-to-diploid transition in Saccharomyces cerevisiae
  1562. Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein
  1563. Combinatorial strategies for the induction of immunogenic cell death
  1564. Studying the Role of Sirtuin-1 Gene in the Maintenance of Mouse Intestinal Epithelium
  1565. The interplay between mitochondrial protein and iron homeostasis and its possible role in ageing
  1566. Post-mitotic protein production causes cell size to increase with replicative age in Saccharomyces cerevisiae
  1567. Pharmacotherapy in the ageing patient: The impact of age per se (A review)
  1568. Quantification of oxygen consumption in retina ex vivo demonstrates limited reserve capacity of photoreceptor mitochondria
  1569. Evolutionary genetic bases of longevity and senescence
  1570. Vitamin E supplementation delays cellular senescence in vitro
  1571. Cell-Autonomous Progeroid Changes in Conditional Mouse Models for
  1572. AGING and balance-A quantitative study of four different balance tasks and the Berg Balance scale on a highly functional elderly sample
  1573. Genetic and epigenomic analyses of Drosophila phenotypes
  1574. Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity
  1575. Damage Segregation and Cellular Rejuvenation in Saccharomyces cerevisiae
  1576. Ubiquitin-mediated regulation of cell death, inflammation, and defense of homeostasis
  1577. Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis
  1578. Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence
  1579. Investigation into the relationships between molecular chaperones, mitochondrial antioxidant enzymes, and endothermic vertebrate longevity
  1580. Ablation of insulin-producing cells prevents obesity but not premature mortality caused by a high-sugar diet in Drosophila
  1581. Rehabilitation concerns in geriatric trauma
  1582. Collaboration between mitochondria and the nucleus is key to long life in Caenorhabditis elegans
  1583. Lithocholic Acid and Macromitophagy Regulate the Dynamics of Lipid Metabolism and Storage to Modulate Chronological AGING in Saccharomyces cerevisiae
  1584. Approaches to in vitro tissue regeneration with application for human disease modeling and drug development
  1585. Mitochondrial DNA rearrangements during human AGING: a study on liver, muscle and adipose tissue
  1586. Nutrition Around the Clock and Inflammation: The Right Food at the Right Time Makes the Difference
  1587. Aerobic Thermogenesis in mtDNA Mutator Mice: Fibroblast Growth Factor 21 at the Nexus of Mitochondrial Stress and Metabolic Adaptation
  1588. Photooxidative damage in retinal pigment epithelial cells via GRP78 and the protective role of grape skin polyphenols
  1589. A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity
  1590. Chronic Lymphocytic Leukemia (CLL)
  1591. Association between diabetes, obesity, AGING, and cancer: review of recent literature
  1592. Acute myeloid leukemia in the elderly patient: new strategies
  1593. Evaluation of traditional medicines for neurodegenerative diseases using Drosophila models
  1594. Isolation and characterization of human endothelial colony forming cells (ECFCs) and effect of oxidative stress on their differentiation
  1595. Regenerative Cells in the Ageing Lung
  1596. Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis
  1597. DNA and chromosomal damage as a hallmark of the induced genomic instability in barley
  1598. Understanding and Reducing Disability in Older Adults Following Critical Illness
  1599. Effects of insulin gene dosage on murine obesity and lifespan
  1600. Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) protects against ceramide-induced cellular toxicity in rat brain astrocytes and neurons by activation of …
  1601. p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload
  1602. Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders
  1603. Research Journal of Pharmaceutical, Biological and Chemical Sciences
  1604. Comparative meta-analysis of transcriptomics data during cellular senescence and in vivo tissue ageing
  1605. Exploring the role of dopamine in stress response and AGING in Drosophila melanogaster – implications for neurodegenerative diseases
  1606. Age-regulated function of autophagy in the mouse inner ear
  1607. Preventing clonal evolutionary processes in cancer: Insights from mathematical models
  1608. Autophagy in colorectal cancer: An important switch from physiology to pathology
  1609. Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance
  1610. Haemocytes control stem cell activity in the Drosophila intestine
  1611. Stress responses during ageing: molecular pathways regulating protein homeostasis
  1612. Mechanisms that influence the posttranslational modification of the GluN2B subunit in the aged brain
  1613. Chromatin plasticity in response to DNA damage: The shape of things to come
  1614. Diabetes and hyperlipidemia induce dysfunction of VSMCs: contribution of the metabolic inflammation/miRNA pathway
  1615. Metal-induced oxidative stress in human fibroblasts: A role in cellular ageing
  1616. Epigenetics, inflammation, and AGING
  1617. Identifying aneuploidy-tolerating genes
  1618. The hair follicle stem cell niche: the bulge and its environment
  1619. Chronological AGING of the Yeast Saccharomyces Cerevisiae Is Linked to a Differentiation Program Converting Quiescent Cells into Non-Quiescent Cells
  1620. Telomerase as a “stemness” enzyme
  1621. The P2X7 receptor in AMD
  1622. Mismatch repair-deficient crypt foci in Lynch syndrome–molecular alterations and association with clinical parameters
  1623. Danika M. Khong, Jarrod A. Dudakov,* Maree V. Hammett, Marc I. Jurblum, Sacha ML Khong, Gabrielle L. Goldberg, Tomoo Ueno, Lisa Spyroglou, Lauren F …
  1624. Metabolic engineering of Saccharomyces cerevisiae for the production of triacetic acid lactone
  1625. Trial Watch: Radioimmunotherapy for oncological indications
  1626. The disruption of proteostasis in neurodegenerative diseases
  1627. Astrocytes require insulin-like growth factor I to protect neurons
  1628. Investigating Genome Instability and Retrotransposition during Replicative AGING in Saccharomyces cerevisiae
  1629. Normal Cell-Type Epigenetics and Breast Cancer Classification: A Case Study of Cell Mixture–Adjusted Analysis of DNA Methylation Data from Tumors …
  1630. Emergent patterns of cellular phenotypes in health and disease
  1631. Coffee induces autophagy in vivo
  1632. Role of microglia in myelin turnover
  1633. The Effect of Pim Kinases Upon Mitochondrial Dynamics and Metabolism
  1634. THE ROLE OF STING IN CANCER
  1635. Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulation
  1636. Modelling of ischemic stroke: focus on co-morbidities and therapeutic intervention
  1637. Protein synthesis as an integral quality control mechanism during ageing
  1638. Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy
  1639. Hutchison-Gilford Progeria Syndrome–A new treatment strategy and the role of prelamin A in oncogenesis
  1640. Hannah Withers, Research Assistant, Rehabilitation Studies Unit, Sydney Medical School Northern, The University of Sydney. Dr Kathryn Higgins, Research …
  1641. Uncovering phenotypes with supercells: applications to single-cell sequencing
  1642. Mechanism of liponecrosis, a distinct mode of programmed cell death
  1643. Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue
  1644. Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis
  1645. Proteomics and Phosphoproteomics of Brain:(1) Analyses of the PINK1 Knockout Model of Parkinson Disease;(2) Insights Into the Progression of Alzheimer Disease; …
  1646. Pim1 kinase functional effect depends upon intracellular localization in human cardiac progenitor cells
  1647. From stem cells to the law courts: DNA methylation, the forensic epigenome and the possibility of a biosocial archive
  1648. Pharmacological diversity among drugs that inhibit bone resorption
  1649. Functional effect of Pim1 depends upon intracellular localization in human cardiac progenitor cells
  1650. Pleiotropic effects of spongean alkaloids on mechanisms of cell death, cell cycle progression and DNA damage response (DDR) of acute myeloid leukemia (AML) …
  1651. Among metabolic factors, significance of fasting and postprandial increases in acyl and desacyl ghrelin and the acyl/desacyl ratio in obstructive sleep apnea before …
  1652. Functional and cellular changes after royalactin treatment in C. elegans
  1653. Diet-induced plasticity in the adult Drosphilia melanogaster midgut
  1654. The role of macrophage migration inhibitory factor in osteoarthritis
  1655. Autophagy in Drosophila: from historical studies to current knowledge
  1656. Guidelines for biomarkers of healthy ageing
  1657. A comparison of differing modalities of exercise on the acute satellite cell responses in older adults
  1658. Long-range and temporal aspects of the genetics of gene expression
  1659. Regulation of the Ran GTPase System and Nucleocytoplasmic Transport
  1660. Computational approaches to understanding the role of fibroblast-myocyte interactions in cardiac arrhythmogenesis
  1661. Sphingolipids and mitochondrial function, lessons learned from yeast
  1662. Rocío de Iriarte Rodríguez, Sara Pulido, Lourdes Rodríguez-de la Rosa, Marta 4
  1663. Mechanistic pathways linking mitochondrial oxidative stress and white matter degeneration in the AGING mammalian female brain
  1664. Epigenetic regulation of alternative splicing in cancer
  1665. TIMPs in Mammary Stem Cell Homeostasis and Breast Cancer Progression
  1666. Lithocholic Acid Extends Yeast Chronological Lifespan, Drives the Evolution of Longevity Regulation Mechanisms in Ecosystems and Suppresses Mitochondrial …
  1667. Progressive lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence of mouse embryonic fibroblasts
  1668. The role of the stress response gene Gadd45b in senescence
  1669. Control of Autophagy in Parkinson’s Disease
  1670. Biological Basis of Ageing, Age-related Diseases and Interventions
  1671. DAF-18/PTEN locally antagonizes insulin signalling to couple germline stem cell proliferation to oocyte needs in C. elegans
  1672. The role of brain and muscle ARNTL 1 (BMAL1) in bone homeostasis
  1673. Principles of studying a cell-a non-boastful paper for all molecular biologists
  1674. Aneuploidy causes proteotoxic stress in Saccharomyces cerevisiae
  1675. Transcriptional network regulated by Caenorhabditis elegans transcription factors CEH-23 and CEP-1 modulates lifespan through AMPK signalings when …
  1676. Asymmetric Division of Damaged Proteins in Proliferating Cells
  1677. Proteolysis mediated by cysteine cathepsins and legumain—recent advances and cell biological challenges
  1678. Interventions for age-related diseases: shifting the
  1679. Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays
  1680. High-throughput Screening of Age-related Changes in Caenorhabditis elegans
  1681. Bazal Hymenoptera (Insecta) Familyalarında Mitokondri Genomunun Evrimi: Hymenoptera Filogenisinin Yeniden Yapılandırılması
  1682. Predicting the pro-longevity or anti-longevity effect of model organism genes with new hierarchical feature selection methods
  1683. Age-related loss of Nrf2, a novel mechanism for the potential attenuation of xenobiotic detoxification capacity
  1684. Quasi-steady-state analysis based on structural modules and timed Petri net predict system’s dynamics: the life cycle of the insulin receptor
  1685. The molecular and epigenetic regulation of osteoblast and osteoclast differentiation and the implications in osteoporosis
  1686. Regulation of Autophagy by Acetyl Coenzime A: From the Mechanisms to a Revised Definition of Caloric Restriction Mimetics
  1687. Repair of bipyrimidine photoproducts at telomeres of ultraviolet light irradiated mammalian cells
  1688. The effects of novel anti-inflammatory nutritional and pharmaceutical supplementation during resistance training on muscle and bone in older adults
  1689. 1 Yeast as a Model for Systems Biology Studies on Complex Diseases
  1690. Investigation of age-related protein changes in the human lens by quasi-elastic light scattering
  1691. Metabolic and Redox Effects of Intermittent Fasting
  1692. TABE OF CONTENTS
  1693. Clinical manifestations of Chikungunya virus infection in HIV infected individuals: a case-control study during the Dominican Republic’s 2014 outbreak
  1694. Body composition, bone health and vitamin D status of African adults in the North West Province
  1695. Specific neutralizing antibody detection against chikungunya virus in HIV-positive and HIV-negative individuals, Dominican Republic 2014
  1696. Telomere Extension Using Modified Tert mRNA to Lengthen Healthspan
  1697. Gene Therapy and Cell Fusion Enhances Stem Cell Mediated Cardiac Repair
  1698. Identification of novel chromatin and nuclear factors regulating oncogene-induced senescence
  1699. Pharmacology: The Pharmacodynamics of Nutrients and Nutrient Interactions in Biological Functions
  1700. Salla Savela
  1701. Influence of sex chromosome complement and hormones on heterochromatin silencing in mice
  1702. Virtue and empirical psychology
  1703. Crosstalk between ceramide and cell signalling pathways controlling chronological lifespan in yeast
  1704. Patent application title: NAD BIOSYNTHESIS AND PRECURSORS FOR THE TREATMENT AND PREVENTION OF CANCER AND PROLIFERATION …
  1705. DETERMINATION OF PRION PROTEIN (PrP) AND CHANGES IN FERTILITY HORMONES WITH SLEEP DEPRIVATION IN ALBINO RATS
  1706. Regulation of Regenerative Responses by Factors in the Extracellular Matrix during Axolotl (Ambystoma mexicanum) Limb Regeneration
  1707. Role of autophagy in neurodegeneration and new for its study
  1708. Stimulus-dependent glucocorticoid receptor signalling in early-life stressed mice
  1709. DIET AND OTHER LIFESTYLE FACTORS IN ADULTHOOD AND INCIDENCE OF CHRONIC DISEASES AND MORTALITY: A PASSIVE-CASE FINDING COHORT …
  1710. Metabolic Engineering of Saccharomyces cerevisiae for the High-Level Synthesis of Polyketides
  1711. Characterization of mitochondrial genomes in bivalve species with doubly uniparental inheritance of mitochondria
  1712. Functionalizing the mitochondrial proteome-mitochondrial metabolism, protein quality control and beyond
  1713. Olive oil and the hallmarks of AGING
  1714. Evidence for the hallmarks of human AGING in replicatively AGING yeast
  1715. Effects of sex, strain, and energy intake on hallmarks of AGING in mice
  1716. Molecular and biological hallmarks of ageing
  1717. Long-term neuroglial cocultures as a brain AGING model: hallmarks of senescence, microRNA expression profiles, and comparison with in vivo models
  1718. In vivo amelioration of age-associated hallmarks by partial reprogramming
  1719. Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells
  1720. Lung fibroblasts, AGING, and idiopathic pulmonary fibrosis
  1721. The hallmarks of cancer from a redox perspective
  1722. The AGING population: demographics and the biology of AGING
  1723. AGING and pulmonary fibrosis
  1724. The role of hydrogen sulfide in AGING and age-related pathologies
  1725. The AGING epigenome
  1726. WNT signaling in lung AGING and disease
  1727. AGING and vision
  1728. Air pollution stress and the AGING phenotype: the telomere connection
  1729. Andrographolide recovers cognitive impairment in a natural model of Alzheimer’s disease (Octodon degus)
  1730. AGING metabolism: evitable or inevitable?
  1731. iPSCs-based anti-AGING therapies: Recent discoveries and future challenges
  1732. Biology of healthy AGING and longevity
  1733. Cardiovascular disease and AGING
  1734. Mitochondrial health in AGING and age-related metabolic disease
  1735. Attenuated anticorrelation between the default and dorsal attention networks with AGING: evidence from task and rest
  1736. Anti-AGING strategies based on cellular reprogramming
  1737. Various mechanistic pathways representing the AGING process are altered in COPD
  1738. The metabolic impact on histone acetylation and transcription in ageing
  1739. Metabolic control of longevity
  1740. Stem cells and AGING
  1741. Two phases of AGING separated by the Smurf transition as a public path to death
  1742. Is chronic obstructive pulmonary disease an accelerated AGING disease?
  1743. Mechanisms of action of curcumin on AGING: nutritional and pharmacological applications
  1744. Nothobranchius furzeri: a model for AGING research and more
  1745. Staying young at heart: autophagy and adaptation to cardiac AGING
  1746. AGING amplifies multiple phenotypic defects in mice with zinc transporter Zip14 (Slc39a14) deletion
  1747. Mitochondrial dysfunction meets senescence
  1748. Induction of nuclear enlargement and senescence by sirtuin inhibitors in glioblastoma cells
  1749. The biology of AGING: citizen scientists and their pets as a bridge between research on model organisms and human subjects
  1750. Mammalian target of rapamycin: a target for (lung) diseases and AGING
  1751. Commentary: XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity
  1752. Proteome-wide changes in protein turnover rates in C. elegans models of longevity and age-related disease
  1753. Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal AGING
  1754. AGING enables Ca 2+ overload and apoptosis induced by amyloid-β oligomers in rat hippocampal neurons: neuroprotection by non-steroidal anti-inflammatory drugs …
  1755. Specific premature epigenetic AGING of cartilage in osteoarthritis
  1756. AMPK function in AGING process
  1757. THE TRUE EFFECTS OF EXERCISE ON HUMAN AGING.
  1758. Disease drivers of AGING
  1759. Age-related DNA methylation changes in normal and osteoarthritis cartilage
  1760. Are aberrant phase transitions a driver of cellular AGING?
  1761. Chaperones and metabolism in Saccharomyces cerevisiae: molecular docking of Hsp90 with Snf1 and Tor1
  1762. The impact of senescence on the zebrafish’s neuroregenerative capacities
  1763. AGING of the immune system: focus on inflammation and vaccination
  1764. Proteome-wide alterations on adipose tissue from obese patients as age-, diabetes-and gender-specific hallmarks
  1765. The role of AGING in Alzheimer’s disease
  1766. The synergistic GIT2-RXFP3 system in the brain and its importance in age-related disorders
  1767. Long noncoding RNAs in diseases of AGING
  1768. Pharmaceutical rejuvenation of age-associated decline in spatial memory
  1769. Early injury of the neonatal lung contributes to premature lung AGING: a hypothesis
  1770. The mitochondrial basis of AGING
  1771. Highly charged proteins: the Achilles’ heel of AGING proteomes
  1772. InflammAGING increases susceptibility to cigarette smoke-induced COPD
  1773. Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: roles of PERK/eIF2α signaling pathway
  1774. Is AGING as inevitable as death and taxes?
  1775. Hdac3 deficiency increases marrow adiposity and induces lipid storage and glucocorticoid metabolism in osteochondroprogenitor cells
  1776. Reprogramming of energy metabolism as a driver of AGING
  1777. Unraveling the links between cancer and AGING
  1778. Functional properties of human stem cell-derived neurons in health and disease
  1779. Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts
  1780. Anti-AGING Effect of Siraitia grosuenorii by Enhancement of Hematopoietic Stem Cell Function
  1781. Microglia: senescence impairs clearance of myelin debris
  1782. Renal AGING and Transplantation
  1783. Relative leukocyte telomere length, hematological parameters and anemia-data from the Berlin AGING Study II (BASE-II)
  1784. Telomere attrition: a window into common mental disorders and cellular AGING
  1785. Molecular mechanisms of biological AGING in intervertebral discs
  1786. Metabolic Control of Longevity
  1787. Mitochondrial Uncoupling Protein Ucp2 Regulates AGING-Related Experimental Lung Fibrosis
  1788. Bursts of reprogramming: a path to extend lifespan?
  1789. Longitudinal RNA-Seq analysis of vertebrate AGING identifies mitochondrial complex I as a small-molecule-sensitive modifier of lifespan
  1790. Moving geroscience into uncharted waters
  1791. Osteoporosis and mechanisms of skeletal AGING
  1792. Comparative biology of AGING: insights from long-lived rodent species
  1793. Ageing and the pathogenesis of osteoarthritis
  1794. Biomarkers of skin AGING
  1795. Osteoarthritis year in review 2015: biology
  1796. Ursolic acid regulates AGING process through enhancing of metabolic sensor proteins level
  1797. Genome integrity in AGING: human syndromes, mouse models, and therapeutic options
  1798. AGING in COPD and idiopathic pulmonary fibrosis
  1799. AGING: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
  1800. Epigenetics and AGING
  1801. The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian AGING and longevity control
  1802. Do DNA double-strand breaks drive AGING?
  1803. The role of immunosenescence in the development of age-related diseases
  1804. Epigenetic Responses to Diet in AGING
  1805. Genetic control of circadian rhythms and AGING
  1806. Evidence of tau hyperphosphorylation and dystrophic microglia in the common marmoset
  1807. Fat-specific Dicer deficiency accelerates AGING and mitigates several effects of dietary restriction in mice
  1808. Molecular basis of nutrition and AGING: a volume in the molecular nutrition series
  1809. Microbes without borders: Decompartmentalization of the AGING gut
  1810. Toward a better understanding of the complexity of cancer drug resistance
  1811. Effects of AGING on slow-wave sleep dynamics and human spatial navigational memory consolidation
  1812. A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of AGING (BLSA)
  1813. Deciphering hallmark processes of AGING from interaction networks
  1814. AGING increases the susceptibility of hepatic inflammation, liver fibrosis and AGING in response to high-fat diet in mice
  1815. role of stem cells in skeletal muscle development, regeneration, repair, AGING, and disease
  1816. Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases
  1817. Effects of AGING on the male reproductive system
  1818. Ageing, neurodegeneration and brain rejuvenation
  1819. Functional networks of AGING markers in the glomeruli of IgA nephropathy: a new therapeutic opportunity
  1820. Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model
  1821. Evolutionary ecology of AGING: time to reconcile field and laboratory research
  1822. Oxidative stress promotes peroxiredoxin hyperoxidation and attenuates pro-survival signaling in AGING chondrocytes
  1823. Pharmaceutical inhibition of mTOR in the common marmoset: effect of rapamycin on regulators of proteostasis in a non-human primate
  1824. Breast cancer beyond the age of mutation
  1825. The role of osteocytes in age-related bone loss
  1826. An update on the pathophysiology of osteoarthritis
  1827. Journal of Ageing Science
  1828. Energetic interventions for healthspan and resiliency with AGING
  1829. Behavioural Science Section/The Berlin AGING Study II–An Overview
  1830. Parkinson’s disease and AGING
  1831. Nutrition and lifestyle in healthy AGING: the telomerase challenge
  1832. What might retrotransposons teach us about AGING?
  1833. Dietary protein, metabolism, and AGING
  1834. Connecting the dots: from DNA damage and repair to AGING
  1835. The emergence of geroscience as an interdisciplinary approach to the enhancement of health span and life span
  1836. Effects and mechanisms of prolongevity induced by Lactobacillus gasseri SBT2055 in Caenorhabditis elegans
  1837. Molecular and cellular basis of AGING
  1838. Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with AGING fRAilTy via intravenoUS delivery (CRATUS) study: a …
  1839. Double strand breaks may be a missing link between entropy and AGING
  1840. Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in AGING and age‐related disorders
  1841. Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans
  1842. Signaling networks determining life span
  1843. Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic
  1844. The essential mechanisms of AGING: what have we learnt in ten years?
  1845. Hair follicle AGING is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
  1846. The chromatin landscape of cellular senescence
  1847. Understanding age-related diseases: report of the 2015 Ageing Summit
  1848. Nutrients and ageing: what can we learn about ageing interactions from animal biology?
  1849. DNA-methylation changes in replicative senescence and AGING: two sides of the same coin?
  1850. Effects of ageing in physical fitness
  1851. Amyloid β protein aggravates neuronal senescence and cognitive deficits in 5XFAD mouse model of Alzheimer’s disease
  1852. Long live FOXO: unraveling the role of FOXO proteins in AGING and longevity
  1853. Nutritional strategies to optimise cognitive function in the AGING brain
  1854. The effect of AGING on brain barriers and the consequences for Alzheimer’s disease development
  1855. Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature AGING
  1856. Developmental drift and the role of wnt signaling in AGING
  1857. iPSCs: on the road to reprogramming AGING
  1858. Targeted therapy for idiopathic pulmonary fibrosis: where to now?
  1859. Role of sirtuins in maintenance of genomic stability: relevance to cancer and healthy AGING
  1860. LncRNA mediated regulation of AGING pathways in Drosophila melanogaster during dietary restriction
  1861. Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2
  1862. A system wide view of replicative AGING in budding yeast
  1863. Timing of expression of the core clock gene Bmal1 influences its effects on AGING and survival
  1864. Epigenetic modifications upon senescence of mesenchymal stem cells
  1865. A mitochondrial perspective of chronic obstructive pulmonary disease pathogenesis
  1866. Mitochondrial ROS produced via reverse electron transport extend animal lifespan
  1867. The influence of pro-longevity gene Gclc overexpression on the age-dependent changes in Drosophila transcriptome and biological functions
  1868. Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie‐restricted mice
  1869. Hutchinson–Gilford progeria syndrome as a model for vascular AGING
  1870. Rejuvenation on the Road to Pluripotency
  1871. Nutrients, foods, dietary patterns and telomere length: Update of epidemiological studies and randomized trials
  1872. Commentary: life course epidemiology embraces geroscience
  1873. Pathology of mouse models of accelerated AGING
  1874. Age-related epigenetic drift and phenotypic plasticity loss: implications in prevention of age-related human diseases
  1875. Life span extension by targeting a link between metabolism and histone acetylation in Drosophila
  1876. Pervasive effects of AGING on gene expression in wild wolves
  1877. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2
  1878. The effect of AGING on mitochondrial complex I and the extent of oxidative stress in the rat brain cortex
  1879. Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1
  1880. Response to hyperoxia is associated with similar ho-1 gene expression level in lungs of AGING CBA mice of both sexes
  1881. Cistanches Herba: a neuropharmacology review
  1882. The role of capillaries in the lesser ailments of old age and in Alzheimer’s disease and vascular dementia: The potential of pro-therapeutic angiogenesis
  1883. Discovery of plant extracts that greatly delay yeast chronological AGING and have different effects on longevity-defining cellular processes
  1884. Modifiable factors influencing telomere length and AGING
  1885. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
  1886. Environmental enrichment modified epigenetic mechanisms in SAMP8 mouse hippocampus by reducing oxidative stress and inflammAGING and achieving …
  1887. Telomeres in AGING and disease: lessons from zebrafish
  1888. Frailty in pulmonary and critical care medicine
  1889. Fendrr Is An Epigenetic Regulator Of Cellular Senescence In Pulmonary Fibroblasts
  1890. FROM REPLICATIVE SENESCENCE TO MICRORNA BASED DIAGNOSTICS OF AGE-ASSOCIATED DISEASES
  1891. Geroscience approaches to increase healthspan and slow AGING
  1892. Role of lncRNAs in cellular AGING
  1893. Molecular insights into the premature AGING disease progeria
  1894. Short telomeres in key tissues initiate local and systemic AGING in zebrafish
  1895. GDF11 administration does not extend lifespan in a mouse model of premature AGING
  1896. Time-dependent dysregulation of autophagy: Implications in AGING and mitochondrial homeostasis in the kidney proximal tubule
  1897. MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity
  1898. Crosstalk of clock gene expression and autophagy in AGING
  1899. “InflammAGING” as a druggable target: a senescence-associated secretory phenotype—centered view of type 2 diabetes
  1900. Selected Theories of Ageing
  1901. Double Strand Breaks May Be a Missing Link between
  1902. Vitamin C alleviates AGING defects in a stem cell model for Werner syndrome
  1903. Pharmacological strategies to retard cardiovascular AGING
  1904. Cellular senescence and lung function during AGING. Yin and Yang
  1905. mberHappily (n) ever after: AGING in the context of oxidative stress, proteostasis loss and cellular senescence
  1906. Ultraviolet radiation-induced skin AGING: the role of DNA damage and oxidative stress in epidermal stem cell damage mediated skin AGING
  1907. Influence of AGING on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal stem cells
  1908. Role of mitochondrial complex IV in age-dependent obesity
  1909. The role of vitamin K in chronic AGING diseases: inflammation, cardiovascular disease, and osteoarthritis
  1910. Characterization of mammary epithelial stem/progenitor cells and their changes with AGING in common marmosets
  1911. High-Throughput Analysis of Age-Dependent Protein Changes in Layer II/III of the Human Orbitofrontal Cortex
  1912. Epigenetic mechanisms of longevity and AGING
  1913. Normal AGING and dementia
  1914. Systematic analysis of the gerontome reveals links between AGING and age-related diseases
  1915. AGING and serum MCP-1 are associated with gut microbiome composition in a murine model
  1916. Early-life stress and reproductive cost: A two-hit developmental model of accelerated AGING?
  1917. The neuronal kinesin UNC-104/KIF1A is a key regulator of synaptic AGING and insulin signaling-regulated memory
  1918. Bcl11a deficiency leads to hematopoietic stem cell defects with an AGING-like phenotype
  1919. Reciprocal changes in phosphoenolpyruvate carboxykinase and pyruvate kinase with age are a determinant of AGING in Caenorhabditis elegans
  1920. Quantitative podocyte parameters predict human native kidney and allograft half-lives
  1921. Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease
  1922. Identifying a New Driver of AGING in C. elegans
  1923. Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche
  1924. Cardiorenal fibrosis and dysfunction in AGING: imbalance in mediators and regulators of collagen
  1925. HIV and AGING
  1926. Vitamin C, antioxidant status, and cardiovascular AGING
  1927. Protein damage, radiation sensitivity and AGING
  1928. A systematic investigation into AGING related genes in brain and their relationship with alzheimer’s disease
  1929. Mitophagy plays a central role in mitochondrial ageing
  1930. Mode-specific physical activity and leukocyte telomere length among US adults: implications of running on cellular AGING
  1931. Oxidative stress, cellular senescence and ageing
  1932. Age-driven developmental drift in the pathogenesis of idiopathic pulmonary fibrosis
  1933. A hidden epithelial barrier in the brain with a central role in regulating brain homeostasis. Implications for AGING
  1934. Cellular Senescence: Spotlight on the Mitochondria
  1935. Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans
  1936. Effect of hyperglycemia on the number of CD117+ progenitor cells and their differentiation toward endothelial progenitor cells in young and old ages
  1937. Biochemical basis of sestrin physiological activities
  1938. Early life origins of adult health and AGING
  1939. Regenerative decline of stem cells in sarcopenia
  1940. Epigenetic targets in cancer and AGING: dietary and therapeutic interventions
  1941. Reversal of phenotypes of cellular senescence by pan-mTOR inhibition
  1942. Roles of renin-angiotensin system and Wnt pathway in AGING-related phenotypes
  1943. Tethering telomerase to telomeres increases genome instability and promotes chronological AGING in yeast
  1944. UPS activation in the battle against AGING and aggregation-related diseases: an extended review
  1945. Pathways for salvage and protection of the heart under stress: novel routes for cardiac rejuvenation
  1946. 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates AGING and Alzheimer’s Disease Progression in Caenorhabditis elegans and Neuronal Cultures
  1947. Global gene profiling of AGING lungs in Atp8b1 mutant mice
  1948. Biomarkers of Replicative Senescence Revisited
  1949. Discover the network mechanisms underlying the connections between AGING and age-related diseases
  1950. A synopsis on AGING—Theories, mechanisms and future prospects
  1951. Deficient activity of the nuclease MRE11A induces T cell AGING and promotes arthritogenic effector functions in patients with rheumatoid arthritis
  1952. Yeast longevity promoted by reversing AGING-associated decline in heavy isotope content
  1953. Effects of senescent lens epithelial cells on the severity of age-related cortical cataract in humans: A case–control study
  1954. Age-related changes in AMPK activation: role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways
  1955. Cellular senescence and autophagy in the pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF)
  1956. Caenorhabditis elegans as a toolkit for studying mammalian AGING pathways
  1957. ROS, cell senescence, and novel molecular mechanisms in AGING and age-related diseases
  1958. Cellular senescence and vascular disease: novel routes to better understanding and therapy
  1959. Water-Transfer Slows AGING in Saccharomyces cerevisiae
  1960. Evidence that hematopoietic stem cell function is preserved during AGING in long-lived S6K1 mutant mice
  1961. Redox mechanisms in age-related lung fibrosis
  1962. Telomere protein RAP1 levels are affected by cellular AGING and oxidative stress
  1963. Age-Related Senescence of Rat Bone Marrow-Derived Mesenchymal Stem Cells
  1964. Therapeutic manipulation of ageing: repurposing old dogs and discovering new tricks
  1965. Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model
  1966. Dissecting the contribution of vascular alterations and AGING to Alzheimer’s disease
  1967. Child poverty and the promise of human capacity: childhood as a foundation for healthy AGING
  1968. The AGING brain: movement speed and spatial control
  1969. Cellular senescence and tumor promotion: is AGING the key?
  1970. Sirt 6 as a novel target for neuroinflammation and brain AGING
  1971. Ultra-weak photon emission of hands in AGING prediction
  1972. Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury
  1973. The evolution of epigenetics: from prokaryotes to humans and its biological consequences
  1974. Introduction to the Theme “Cancer Pharmacology”
  1975. The role of autophagy, mitophagy and lysosomal functions in modulating bioenergetics and survival in the context of redox and proteotoxic damage …
  1976. Leukocyte telomere length and mortality risk in patients with type 2 diabetes
  1977. Classification for longevity potential: the use of novel biomarkers
  1978. Effects of dietary restriction on adipose mass and biomarkers of healthy AGING in human
  1979. Metabolism and the UPRmt
  1980. Keeping the senescence secretome under control: molecular reins on the senescence-associated secretory phenotype
  1981. Neuroendocrinology of AGING
  1982. Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts
  1983. Genomic stability during cellular reprogramming: mission impossible?
  1984. Derailed proteostasis as a determinant of cardiac AGING
  1985. The impact of AGING on cancer progression and treatment
  1986. Two conserved histone demethylases regulate mitochondrial stress-induced longevity
  1987. Modifiers of Neural Stem Cells and AGING: Pulling the Trigger of a Neurogenic Decline
  1988. Gene expression signatures of human cell and tissue longevity
  1989. Mitochondria and oxidative stress in heart AGING
  1990. DNA damage: a main determinant of vascular AGING
  1991. Unraveling Stochastic AGING Processes in Mouse Liver: Dissecting Biological from Chronological Age
  1992. On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae)
  1993. MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism
  1994. Cancer stem cells: basic concepts and therapeutic implications
  1995. The novel dipeptide Tyr-Ala (TA) significantly enhances the lifespan and healthspan of Caenorhabditis elegans
  1996. What we know about the pathogenesis of idiopathic pulmonary fibrosis
  1997. Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis
  1998. DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age
  1999. Beyond diabetes: does obesity-induced oxidative stress drive the AGING process?
  2000. Coenzyme Q biosynthesis and its role in the respiratory chain structure
  2001. The impact of low-protein high-carbohydrate diets on AGING and lifespan
  2002. Profiling IgG N-glycans as potential biomarker of chronological and biological ages: A community-based study in a Han Chinese population
  2003. Epigenetic significance of chromatin organization during cellular AGING and organismal lifespan
  2004. In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state
  2005. Mitochondrial form, function and signalling in AGING
  2006. Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with AGING in male and female mice
  2007. Absence of non-histone protein complexes at natural chromosomal pause sites results in reduced replication pausing in AGING yeast cells
  2008. Age intrinsic loss of telomere protection via TRF1 reduction in endothelial cells
  2009. Diastolic dysfunction and cardiac troponin I decrease in AGING hearts
  2010. Nrf2 signaling and redox homeostasis in the AGING heart: a potential target to prevent cardiovascular diseases?
  2011. Molecular and Genetic Investigation of AGING: The Role of Mitochondrial Metabolism Genes on Life Span Determination
  2012. In search of lost time: age and the promise of induced pluripotent stem cell models of the brain
  2013. The Effects of Rapamycin on the Unfolded Protein Response in Relation to Healthy AGING
  2014. Increased levels of hyper-stable protein aggregates in plasma of older adults
  2015. Exercise: a “new drug” for elderly patients with chronic heart failure
  2016. QUALITY-OF-LIFE OUTCOMES OF AGING ADULTS WITH AUTISM AND THEIR FAMILIES
  2017. Systemic DNA damage responses in AGING and diseases
  2018. Glycomics and glycoproteomics focused on AGING and age-related diseases—Glycans as a potential biomarker for physiological alterations
  2019. Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila
  2020. Protective effect of seleno-β-lactoglobulin (Se-β-lg) against oxidative stress in D-galactose-induced AGING mice
  2021. Early-life intelligence predicts midlife biological age
  2022. AGING and the HPA axis: Stress and resilience in older adults
  2023. The role of stem cell AGING in acute myeloid leukemia.
  2024. Forkhead-box A1 induces cell senescence in endometrial cancer by regulating p16INK4a
  2025. SESSION 300 (SYMPOSIUM)
  2026. Age-dependent changes in the activation and regulation of microglia
  2027. Finding Ponce de Leon’s pill: challenges in screening for anti-AGING molecules
  2028. Mechanisms and consequences of cancer genome instability: lessons from genome sequencing studies
  2029. Regulation of Stem Cells in Their Niche
  2030. Orchestrating the network of molecular pathways affecting AGING: role of nonselective autophagy and mitophagy
  2031. Understanding vascular diseases: lessons from premature AGING syndromes
  2032. Uncoupling protein 2 protects mice from AGING
  2033. Long-term dietary alpha-linolenic acid supplement alleviates cognitive impairment correlate with activating hippocampal CREB signaling in natural AGING rats
  2034. Long noncoding RNAs in AGING and age-related diseases
  2035. Six plant extracts delay yeast chronological AGING through different signaling pathways
  2036. Osteoarthritis in the Elderly
  2037. Epigenetic regulations of hematopoietic stem cells ageing and the regulation of traditional Chinese medicine
  2038. Living long and well: prospects for a personalized approach to the medicine of ageing
  2039. Mitochondria and senescence: new actors for an old play
  2040. Citation metadata
  2041. Hematopoiesis during development, AGING, and disease
  2042. Chromothripsis and epigenomics complete causality criteria for cannabis-and addiction-connected carcinogenicity, congenital toxicity and heritable genotoxicity
  2043. Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR
  2044. The anti-AGING effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain
  2045. Animal models of frailty: current applications in clinical research
  2046. Generating late-onset human iPSC-based disease models by inducing neuronal age-related phenotypes through telomerase manipulation
  2047. Extracellular vesicles in chronic obstructive pulmonary disease
  2048. Audition and language comprehension in adult AGING: Stability in the face of change
  2049. Extracellular vesicles as new players in cellular senescence
  2050. Towards a multidimensional healthy ageing phenotype
  2051. Protective effect of ginsenoside Rg1 on hematopoietic stem/progenitor cells through attenuating oxidative stress and the Wnt/β-catenin signaling pathway in a mouse …
  2052. Poly (ADP-Ribose) Polymerases in AGING–Friend or Foe?
  2053. Accelerated accumulation of multimorbidity after bilateral oophorectomy: a population-based cohort study
  2054. Ageing and the telomere connection: An intimate relationship with inflammation
  2055. Metabolomics of Mammalian and Cellular Models of AGING
  2056. Sirtuins, healthspan, and longevity in mammals
  2057. Species-specific lifespans: Can it be a lottery based on the mode of mitochondrial DNA replication?
  2058. A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia
  2059. Amniotic epithelial cells: a new tool to combat AGING and age-related diseases?
  2060. Nuclear DNA damage signalling to mitochondria in ageing
  2061. The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
  2062. Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagy
  2063. Genome-wide DNA methylation changes during AGING
  2064. Understanding and predicting protein misfolding and aggregation: Insights from proteomics
  2065. Reorganization of chromosome architecture in replicative cellular senescence
  2066. Notable decrease in transcriptome conservation during mammalian AGING
  2067. The short-lived African turquoise killifish: an emerging experimental model for ageing
  2068. Human neural stem cell AGING is counteracted by α-glycerylphosphorylethanolamine
  2069. The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
  2070. Reverse geroscience: how does exposure to early diseases accelerate the age‐related decline in health?
  2071. Strategies and challenges in clinical trials targeting human AGING
  2072. From paediatrics to geriatrics: a life course perspective on the MRC National Survey of Health and Development
  2073. Phycocyanin moderates AGING and proteotoxicity in Caenorhabditis elegans
  2074. Chaperone mediated autophagy in AGING: starve to prosper
  2075. Cell-nonautonomous mechanisms underlying cellular and organismal AGING
  2076. Crosstalk between cellular compartments protects against proteotoxicity and extends lifespan
  2077. The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
  2078. Caloric restriction: beneficial effects on brain AGING and Alzheimer’s disease
  2079. XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence
  2080. Habituation in the tail withdrawal reflex circuit is impaired during AGING in Aplysia californica
  2081. Optical monitoring of retinal respiration in real time: 670 nm light increases the redox state of mitochondria
  2082. Ageing as an important risk factor for cancer
  2083. Animal and human models to understand ageing
  2084. Stem Cell Therapies for Cardiac Regeneration: Current Burden—Future Directions
  2085. Effects of AGING and short-term dietary restriction on neurogenesis and cellular senescence in the zebrafish (Danio Reio) brain
  2086. Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice
  2087. Supplementation with Lactobacillus plantarum WCFS1 prevents decline of mucus barrier in colon of accelerated AGING Ercc1−/Δ7 mice
  2088. Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho–Deficient Model
  2089. Longevity of animals under reactive oxygen species stress and disease susceptibility due to global warming
  2090. Interaction of age at diagnosis with transcriptional profiling in papillary thyroid cancer
  2091. Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation
  2092. The utility of preoperative frailty assessment
  2093. Identification of potential key lncRNAs and genes associated with AGING based on microarray data of adipocytes from mice
  2094. Variation of global DNA methylation levels with age and in autistic children
  2095. Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
  2096. Predicting disease onset in clinically healthy people
  2097. Peptides from sesame cake extend healthspan of Caenorhabditis elegans via upregulation of skn-1 and inhibition of intracellular ROS levels
  2098. A shape shifting organelle: unusual mitochondrial phenotype determined with three-dimensional electron microscopy reconstruction
  2099. Nutrigenomics and Nutrigenetics: The Basis of Molecular Nutrition
  2100. EPIGENETIC FACTORS IN CARDIOVASCULAR DISEASE. AGEING STUDIES. REVIEW
  2101. Alzheimer’s as a systems-level disease involving the interplay of multiple cellular networks
  2102. Changes in frailty predict changes in cognition in older men: the Honolulu-Asia AGING Study
  2103. Interventions for human frailty: physical activity as a model
  2104. Diet-induced phenotypic plasticity during AGING
  2105. Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
  2106. Stress-induced (Premature) senescence
  2107. Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants
  2108. Therapy of endocrine disease: improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing’s …
  2109. Stem cells: a renaissance in human biology research
  2110. Review of recent studies and research analysis for anti-oxidant and anti-AGING materials
  2111. HIV and ageing: improving quantity and quality of life
  2112. NADPH oxidases: key modulators in AGING and age-related cardiovascular diseases?
  2113. An Accumulation of Senescent Cells May Contribute to Chronic Inflammation of the Mammalian Liver
  2114. A diphenyl diselenide-supplemented diet and swimming exercise promote neuroprotection, reduced cell apoptosis and glial cell activation in the hypothalamus of old …
  2115. The protective role of protein L-isoaspartyl (D-aspartate) O-methyltransferase for maintenance of mitochondrial morphology in A549 cell
  2116. Behaviour and cognitive changes correlated with hippocampal neuroinflammAGING and neuronal markers in female SAMP8, a model of accelerated senescence
  2117. Cell fusion proteins can rejuvenate adult dendritic trees
  2118. AMPK as a pro-longevity target
  2119. Contextual adversity, telomere erosion, pubertal development, and health: Two models of accelerated AGING, or one?
  2120. A frailty index based on laboratory deficits in community-dwelling men predicted their risk of adverse health outcomes
  2121. Simplified assay for epigenetic age estimation in whole blood of adults
  2122. Grundy, Richard G.(2015) Expression alterations define unique molecular characteristics of spinal ependymomas. Oncotarget, 6 (23). pp. 19780-19791. ISSN …
  2123. Secondary progression in multiple sclerosis: neuronal exhaustion or distinct pathology?
  2124. Endothelial cell senescence and inflammAGING: microRNAs as biomarkers and innovative therapeutic tools
  2125. Telomere attrition and restoration in the normal teleost Oryzias latipes are linked to growth rate and telomerase activity at each life stage
  2126. Mitochondria quality control and muscle mass maintenance
  2127. Measuring biological age via metabonomics: the metabolic age score
  2128. A short leucocyte telomere length is associated with development of insulin resistance
  2129. Combined associations of body weight and lifestyle factors with all cause and cause specific mortality in men and women: prospective cohort study
  2130. Change in epigenome-wide DNA methylation over 9 years and subsequent mortality: results from the InCHIANTI Study
  2131. The proteasome and oxidative stress in Alzheimer’s disease
  2132. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes
  2133. Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing
  2134. Ageing: consequences of excessive free radicals and inflammation
  2135. Genomic Instability and AGING: Causes and Consequences
  2136. Systematic and cell type-specific telomere length changes in subsets of lymphocytes
  2137. Common SIRT1 variants modify the effect of abdominal adipose tissue on AGING-related lung function decline
  2138. Regulation of mitochondrial dynamics and bioenergetics: implications of circadian clock and neurosteroids in health and diseases
  2139. Mitochondrial reactive oxygen species: do they extend or shorten animal lifespan?
  2140. Evaluation of candidate reference genes for RT-qPCR studies in three metabolism related tissues of mice after caloric restriction
  2141. Alterations of mitochondrial DNA copy number and telomere length with early adversity and psychopathology
  2142. From DNA damage to functional changes of the trabecular meshwork in AGING and glaucoma
  2143. 39 ROS and Epigenetics
  2144. Effect of Maternal Age on Offspring Social Behaviour in Drosophila Melanogaster
  2145. TNFA gene variants related to the inflammatory status and its association with cellular AGING: from the CORDIOPREV study
  2146. A genetic interaction between rap 1 and telomerase reveals an unanticipated role for rap 1 in telomere maintenance
  2147. Muscle-Related Polymorphisms (MSTN rs1805086 and ACTN3 rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians
  2148. Periodic acid-Schiff granules in the brain of aged mice: From amyloid aggregates to degenerative structures containing neo-epitopes
  2149. Shared biologic pathways between Alzheimer disease and major depression: a systematic review of MicroRNA expression studies
  2150. Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan
  2151. Inside out: the role of nucleocytoplasmic transport in ALS and FTLD
  2152. Gerontology versus geriatrics: different ways of understanding ageing and old age
  2153. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
  2154. Increased Protein Stability and Decreased Protein Turnover in the Caenorhabditis elegans Ins/IGF-1 daf-2 Mutant
  2155. Discovery of Plant Extracts That Delay Yeast Chronological AGING through Different Signaling Pathways
  2156. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila
  2157. When science meets cluttered writing: adjectives and adverbs in academia revisited
  2158. Effects of aerobic training on markers of autophagy in the elderly
  2159. Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli
  2160. Replication-independent histone variant H3. 3 controls animal lifespan through the regulation of pro-longevity transcriptional programs
  2161. Associations between long-term serum platinum and neurotoxicity and ototoxicity, endocrine gonadal function, and cardiovascular disease in testicular cancer …
  2162. Genetic Manipulation of Glycogen Allocation Affects Replicative Lifespan in E. coli
  2163. Temporal development of autonomic dysfunction in heart failure: effects of age in an ovine rapid-pacing model
  2164. Revista de
  2165. Shortened telomere length in patients with depression: a meta-analytic study
  2166. Heterochronic parabiosis studies of the AGING immune system
  2167. A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis
  2168. Diabetes and AGING
  2169. The aged lymphoid tissue environment fails to support naïve T cell homeostasis
  2170. Mechanosensory neuron AGING: differential trajectories with lifespan-extending Alaskan berry and fungal treatments in Caenorhabditis elegans
  2171. Understanding the physiology of the ageing individual: computational modelling of changes in metabolism and endurance
  2172. Induction of renal senescence marker protein-30 (SMP30) expression by testosterone and its contribution to urinary calcium absorption in male rats
  2173. Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling
  2174. Reliability of the 6-minute walk test and cardiac autonomic markers in active and sedentary older women
  2175. TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response
  2176. Selective disappearance of individuals with high levels of glycated haemoglobin in a free-living bird
  2177. Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy …
  2178. MAP3K19 is a novel regulator of TGF-β signaling that impacts bleomycin-induced lung injury and pulmonary fibrosis
  2179. Periodic acid-Schiff granules in the brain of aged mice: from amyloid aggregates to degenerative structures containing neo-epitopes
  2180. Enhancer Remodeling During Early Mammalian Embryogenesis: Lessons for Somatic Reprogramming, Rejuvenation, and AGING
  2181. Lysosomal cathepsins and their regulation in AGING and neurodegeneration
  2182. Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2
  2183. Epigenetic and Pten Regulation of Longevity Pathways Related to Idiopathic Pulmonary Fibrosis and Organismal AGING
  2184. Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice
  2185. Mammalian target of rapamycin (mTOR), AGING, neuroscience, and their association with AGING-related diseases
  2186. Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals
  2187. Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival
  2188. Emotions and family interactions in childhood: Associations with leukocyte telomere length
  2189. Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms
  2190. Proteostasis alterations in myeloproliferative neoplasms: Oncogenic relevance and therapeutic opportunities
  2191. Are invertebrates relevant models in ageing research? Focus on the effects of rapamycin on TOR
  2192. Validation and comparison of instruments to identify frail patientes in primary care settings: study protocol
  2193. Roles of apoptosis and cellular senescence in cancer and AGING
  2194. Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
  2195. Glutathione maintenance mitigates age-related susceptibility to redox cycling agents
  2196. Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease
  2197. Stem Cell AGING Research Literatures
  2198. Key role of DAMP in inflammation, cancer, and tissue repair
  2199. Influence of ageing on tendon homeostasis
  2200. Nutrition in the Elderly: General Aspects
  2201. Maintenance of the adult Drosophila intestine: all roads lead to homeostasis
  2202. Phenomenon of ageing–a process or a state
  2203. Epigenetic perturbations in AGING stem cells
  2204. Treatment of facial photodamage and rhytides using a novel 1,565 nm non‐ablative fractional erbium‐doped fiber laser
  2205. Identification of longevity and cancer resistance mechanisms in long-lived rodent species
  2206. Reflections on the role of senescence during development and AGING
  2207. DNA damage response in hematopoietic stem cell ageing
  2208. Role of telomerase in the cardiovascular system
  2209. p53 and the carcinogenicity of chronic inflammation
  2210. Genetics and idiopathic interstitial pneumonias
  2211. Targeting Senescent Cells to Improve Human Health
  2212. Effects of age and working memory capacity on speech recognition performance in noise among listeners with normal hearing
  2213. Prostate cancer: is it a battle lost to age?
  2214. The association of serum cathepsin B concentration with age-related cardiovascular-renal subclinical state in a healthy Chinese population
  2215. Histone modifications in ageing and lifespan regulation
  2216. Mammalian telomeres and their partnership with lamins
  2217. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells
  2218. Sirt6 links genome stability and tumor suppression pathways to longevity maintenance
  2219. Cardioprotection and lifespan extension by the natural polyamine spermidine
  2220. Ageing in the musculoskeletal system: cellular function and dysfunction throughout life
  2221. Hypermethylation of FOXP3 Promoter and Premature AGING of the Immune System in Female Patients with Panic Disorder?
  2222. Improving mitochondrial function protects bumblebees from neonicotinoid pesticides
  2223. Hitting the high notes: Healthy AGING in professional orchestral musicians
  2224. Practical Laboratory Medicine
  2225. Mechanisms of lung fibrosis resolution
  2226. Menopause: genome stability as new paradigm
  2227. Integrated multiregional analysis proposing a new model of colorectal cancer evolution
  2228. The pathophysiology of defective proteostasis in the hypothalamus—from obesity to ageing
  2229. High fat diet exacerbates Alzheimer’s disease-related pathology in APPswe/PS1 mice
  2230. Understanding long-term outcomes following sepsis: implications and challenges
  2231. Chromatin Signaling in AGING and Cellular Senescence
  2232. rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts
  2233. Age-dependent modulation of fasting and long-term dietary restriction on acetylcholinesterase in non-neuronal tissues of mice
  2234. Connecting the functions of the proteasome and mitochondria in the lung
  2235. LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR
  2236. Protective effects of α-tocopherol, γ-tocopherol and oleic acid, three compounds of olive oils, and no effect of trolox, on 7-ketocholesterol-induced …
  2237. Hyperglycemic stress and carbon stress in diabetic glucotoxicity
  2238. Age-dependent pancreatic gene regulation reveals mechanisms governing human β cell function
  2239. Translational control in nutrient response and AGING
  2240. Physical activity and Alzheimer disease: a protective association
  2241. TEMPOL increases NAD+ and improves redox imbalance in obese mice
  2242. Age-related changes in basal substrate oxidation and visceral adiposity and their association with metabolic syndrome
  2243. HSF1 regulation in AGING and its role in longevity
  2244. Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance
  2245. Effects of low-dose ibuprofen supplementation and resistance training on bone and muscle in postmenopausal women: a randomized controlled trial
  2246. Vitamin C improves the health span of animal models of werner syndrome
  2247. Telomere shortening in middle-aged men with sleep-disordered breathing
  2248. DECLINE IN BLOOD HEMOGLOBIN CONCENTRATION IS ASSOCIATED WITH FAMILIAL LONGEVITY
  2249. The redundancy of the mammalian heterochromatic compartment
  2250. Exploring the homeostatic and sensory roles of the immune system
  2251. Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies
  2252. MMP-25 metalloprotease regulates innate immune response through NF-κB signaling
  2253. Involvement of Daphnia pulicaria Sir2 in regulating stress response and lifespan
  2254. Creation of databases of ageing-related drugs and statistical analysis and applied machine learning for the prioritization of potential lifespan-extension drugs
  2255. The germline/soma dichotomy: implications for AGING and degenerative disease
  2256. Physiological and pathological AGING affects chromatin dynamics, structure and function at the nuclear edge
  2257. Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes
  2258. Circulating microRNAs during human AGING and longevity
  2259. Unabridged analysis of human histone H3 by differential top-down mass spectrometry reveals hypermethylated proteoforms from MMSET/NSD2 …
  2260. Mitochondrial health, the epigenome and healthspan
  2261. Stage dependent nutritional regulation of transgenerational longevity
  2262. Critical role of lysosomes in the dysfunction of human Cardiac Stem Cells obtained from failing hearts
  2263. Systemic immune markers characterizing early stages of rheumatoid arthritis
  2264. Mir-184 affects lifespan via regulating the Activin pathway in Drosophila
  2265. Longer telomeres in chronic, moderate, unconjugated hyperbilirubinaemia: insights from a human study on Gilbert’s Syndrome
  2266. Calculating the rate of senescence from mortality data: an analysis of data from the ERA-EDTA Registry
  2267. Biological rationale for regular physical exercise as an effective intervention for the prevention and treatment of depressive disorders
  2268. HIV and AGING: parallels and synergistic mechanisms leading to premature disease and functional decline
  2269. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
  2270. Optimization of reference genes for normalization of reverse transcription quantitative real-time polymerase chain reaction results in senescence study of …
  2271. GIT2 acts as a systems-level coordinator of neurometabolic activity and pathophysiological AGING
  2272. Changes in mitochondrial fitness of fibroblasts due to oxidative stress
  2273. AGING, AGING Process and Roles of Genes in AGING
  2274. Relative contributions of arterial stiffness and hypertension to cardiovascular disease: the Framingham Heart Study
  2275. Candidate genes of idiopathic pulmonary fibrosis: current evidence and research
  2276. Weight loss upregulates the small GTPase DIRAS3 in human white adipose progenitor cells, which negatively regulates adipogenesis and activates …
  2277. A role for Mfb1p in region-specific anchorage of high-functioning mitochondria and lifespan in Saccharomyces cerevisiae
  2278. Polyketide-based anti-AGING therapeutic development via synthetic enzymology
  2279. Cellular Memory of Adverse Intrauterine Nutrition Associated with Altered Cell Function and Epigenetic Dysregulation
  2280. Metabolic control of methylation and acetylation
  2281. Neuromodulatory potential of aqueous extracts of cumin, cinnamon: evidence from rotenone model in drosophila: implications to Parkinson’s disease
  2282. SCC ONTARIO EDUCATION DAY
  2283. BubR1 in cancer, AGING and development
  2284. The health benefits of exercise and physical activity
  2285. Autophagy maintains stemness by preventing senescence
  2286. Long noncoding RNAs in HPV-induced oncogenesis
  2287. AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions
  2288. Discarded human thymus is a novel source of stable and long‐lived therapeutic regulatory T cells
  2289. Changes in Drosophila mitochondrial proteins following chaperone-mediated lifespan extension confirm a role of Hsp22 in mitochondrial UPR and reveal a …
  2290. SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks
  2291. Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3′ ends in Drosophila
  2292. Dianna T. Kenny and
  2293. The transcriptional repressor Sum1p counteracts Sir2p in regulation of the actin cytoskeleton, mitochondrial quality control and replicative lifespan in …
  2294. Screening for frailty in Canada’s health care system: a time for action
  2295. Estradiol-induced transcriptional regulation of long non-coding RNA, HOTAIR
  2296. NF-κB signaling as a driver of ageing
  2297. Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation
  2298. Investigate the role of Nrip1 in metabolic AGING and longevity in mouse model
  2299. BTK modulates p53 activity to enhance apoptotic and senescent responses
  2300. Systematic review of the association between chronic social stress and telomere length: A life course perspective
  2301. Genes Related to Fatty Acid β-Oxidation Play a Role in the Functional Decline of the Drosophila Brain with Age
  2302. Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability
  2303. Older age is associated with more MRI-detected inflammation in hand and foot joints
  2304. Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome
  2305. The impact of the eye in dementia: the eye and its role in diagnosis and follow-up
  2306. AUTEN-67 (autophagy enhancer-67) hampers the progression of neurodegenerative symptoms in a Drosophila model of Huntington’s disease
  2307. Socio-demographic and Health Aspects Associated with the Quality of Life in the Elderly of the Family Health Strategy. An Analytical Study.
  2308. Loss of Nat4 and its associated histone H4 N‐terminal acetylation mediates calorie restriction‐induced longevity
  2309. Mitochondria-targeting ceria nanoparticles as antioxidants for Alzheimer’s disease
  2310. SIRT 7 promotes genome integrity and modulates non‐homologous end joining DNA repair
  2311. TNF‐α inhibits FoxO1 by upregulating miR‐705 to aggravate oxidative damage in bone marrow‐derived mesenchymal stem cells during osteoporosis
  2312. Senescence associated heterochromatic foci: SAHF
  2313. Profiling IgG N-glycans as potential biomarker of chronological and biological ages
  2314. EQ-5D-5L in the general German population: comparison and evaluation of three yearly cross-section surveys
  2315. Lysosomal cathepsins and their regulation in AGING and
  2316. Insights into long noncoding RNAs of naked mole rat (Heterocephalus glaber) and their potential association with cancer resistance
  2317. Characterisation of Novel Markers and Effectors of Senescence and their Role in Cancer and Ageing
  2318. Interaction of mouse splenocytes and macrophages with bacterial strains in vitro: the effect of age in the immune response
  2319. Current advances in the functional studies of fatty acids and fatty acid-derived lipids in C. elegans
  2320. Targeting mitochondrial phenotypes for non-communicable diseases
  2321. Sumoylation in cellular senescence and AGING
  2322. Nontranscriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis
  2323. Differential proteomic analysis of human placenta-derived mesenchymal stem cells cultured on normal tissue culture surface and hyaluronan-coated surface
  2324. Integrity of the Barrier Epithelium in Drosophila Gut is Mediated by Factors That Regulate Intestinal Stem Cell Activity
  2325. Polyphenol-related epigenetic modifications in osteoarthritis: current therapeutic perspectives
  2326. Altered Expression of Cellular Markers in Molecular Brain AGING
  2327. Application of Bioinformatics Methodologies in the Fields of Skin Biology and Dermatology
  2328. Impaired epidermal to dendritic T cell signaling slows wound repair in aged skin
  2329. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo
  2330. Optimizing pharmacological lifespan extension: Testing chemical compounds for additive effects on longevity
  2331. Phylloquinone and menaquinone-4 tissue distribution at different life stages in male and female Sprague–Dawley rats fed different VK levels since weaning or …
  2332. Reversing stem cell AGING: Implications for vascular regeneration
  2333. Sedentary time, cardiorespiratory fitness, and cardiovascular risk factor clustering in older adults–the Generation 100 study
  2334. Expression profiling and functional prediction of long noncoding RNAs in nasopharyngeal nonkeratinizing carcinoma
  2335. Uncovering the mechanisms of Caenorhabditis elegans ageing from global quantification of the underlying landscape
  2336. Nutritional issues in geriatric care: nutrition and HIV
  2337. Interactions between Innate Immune Signaling, Gut Microbiota, and Tissue Regeneration in the Control of Homeostasis in the AGING Fly Intestine
  2338. Long noncoding RNA POU6F2-AS2 is associated with oesophageal squamous cell carcinoma
  2339. On the interplay between chronic pain and age with regard to neurocognitive integrity: Two interacting conditions?
  2340. Proteostatic Mechanisms and Degree of Transcriptional Change with Age in Different Neural Stem Cell Populations
  2341. Bone Reports
  2342. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing
  2343. Regulation and Role of Mirna and Target Genes in Cell Cycle during Oxidative Stress-Induced Premature Senescence in Mesenchymal Stem Cell
  2344. THAI DERMATOLOGIST SURVEY OF SKIN AGING ASSESSMENT
  2345. Mechanisms of mitophagy: putting the powerhouse into the doghouse
  2346. IGF-1 levels are inversely associated with metabolic syndrome in obstructive sleep apnea
  2347. Histone H3 and TORC1 prevent organelle dysfunction and cell death by promoting nuclear retention of HMGB proteins
  2348. Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence
  2349. Current evidence for developmental, structural, and functional brain defects following prenatal radiation exposure
  2350. Aneuploidy impairs protein folding and genome integrity in human cells
  2351. Analysis of Deleted in Breast Cancer 1 (DBC1} as a Novel Molecular Target of Resveratrol and Its Metabolites
  2352. Physiological responding to stress in middle-aged males enriched for longevity: a social stress study
  2353. Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq
  2354. Exosomes in the Preservation of Cellular Homeostasis
  2355. Identification of novel lipid signalling mechanisms
  2356. Application of bioactive quercetin in oncotherapy: from nutrition to nanomedicine
  2357. Studies on the regulation of genome maintenance factors by non-covalent interaction with poly (ADP-ribose) with a focus on RECQL helicases
  2358. Non-thermal atmospheric pressure plasma efficiently promotes the proliferation of adipose tissue-derived stem cells by activating NO-response pathways
  2359. Moonlight-like proteins of the cell wall protect sessile cells of Candida from oxidative stress
  2360. 1, 4-Dihydropyridines active on the SIRT1/AMPK pathway ameliorate skin repair and mitochondrial function and exhibit inhibition of proliferation in cancer cells
  2361. Cross talk of proteostasis and mitostasis in cellular homeodynamics, ageing, and disease
  2362. Tomato aqueous extract modulates the inflammatory profile of immune cells and endothelial cells
  2363. Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice
  2364. Modulation of gluconeogenesis and lipid production in an engineered oleaginous Saccharomyces cerevisiae transformant
  2365. Structure and function of the mitochondrial ribosome
  2366. Telomere dysfunction drives pulmonary fibrosis and offers new therapeutic strategies
  2367. The safety of treatment options for elderly people with acute myeloid leukemia
  2368. Studying the effects of Ubisol-Q10 in animal models of Alzheimer’s and Parkinson’s disease
  2369. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis
  2370. A Modest Proposal: Differentiating Daughters are Sacrificed during Starvation to Protect Stem Cells in the Drosophila Testis.
  2371. Chemopreventive and therapeutic effects of edible berries: A focus on colon cancer prevention and treatment
  2372. Studies on Molecular Basis for FOXO1-DNA Damage Responses
  2373. Comprehension and effort for vocoded speech varying in syntactic complexity
  2374. Epigenomics-based identification of major cell identity regulators within heterogeneous cell populations
  2375. Disparities in Environmental Exposures and Health in Thailand: Molecular Effects of Chronic Cadmium Exposure and Trends in Childhood Leukemia
  2376. The impact of oxidative stress induced RNA granules on cellular senescence
  2377. Agonist-stimulated phosphatidylinositol-3, 4, 5-trisphosphate generation by scaffolded phosphoinositide kinases
  2378. A Novel Mechanism of Spermatogonia Death in Drosophila that Contributes to Tissue Homeostatis During Starvation.
  2379. Evidence supporting the utility of blood cell respiratory capacity as a systemic marker of mitochondrial health and biological age
  2380. Prevention of chronic conditions and cancer
  2381. WAKE FOREST UNIVERSITY SCHOOL OF MEDICINE
  2382. Rational Autologous Cell Sources For Therapy of Heart Failure–Vehicles and Targets For Gene and RNA Therapies
  2383. HIV-1 gp120 mediated neuronal deregulation: Unraveling the molecular mechanisms involved
  2384. The Influence of Antithymocyte Globulin on CD4+ T Cells from Patients with Rheumatoid Arthritis
  2385. Fibrocytes, y-Herpesvirus and Periostin Augment Bleomycin-induced Lung Fibrosis.
  2386. Autophagy and inflammation in the pathogenesis of idiopathic dilated cardiomyopathy
  2387. The ageing muscle: Macrophage kinetics and local inflammation in response to resistance training
  2388. Does Androgen Deprivation Therapy Impact Subjective Cognitive Function in Men with Non-metastatic Prostate Cancer?
  2389. The orphan drug 4-phenyl butyrate protects the heart against Atrial Fibrillation by blocking ER stress-induced autophagy
  2390. Modeling CNS Development and
  2391. “It’s not how old we are; it’s how we are old”: A salutogenic approach to how older Australian women experience ageing and respond to life stressors
  2392. Redox Status and Proteostasis in Ageing and Disease
  2393. The Molecular Mechanisms of MAP4K3-mediated Autophagy Induction
  2394. Identification of Pathogenic Determinants and Mechanisms of C9ORF72 linked ALS/FTD
  2395. Dysfunctional phenotype of T cells and their contribution to impaired B cell function during HIV-1 infection
  2396. NAD LIMITATION AND ITS IMPACT ON C. GLABRATA SURVIVAL AND VIRULENCE
  2397. Health-related quality of life outcomes following primary percutaneous coronary intervention for ST-elevation myocardial infarction (HOOP-PCI study)
  2398. Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening
  2399. IIM secretary e-mail: fisiologia@ unich. it D’Alfonso Antonella Info: www. co ra mi im. it
  2400. Annales Universitatis Paedagogicae Cracoviensis. 215. Studia ad Didacticam Biologiae Pertinentia 6
  2401. Establishment an in vitro primary mouse hepatocyte model to investigate the modes of action of carcinogens carcinogens study∗
  2402. A transthyretin-related gene
  2403. Obstructive sleep apnea and hallmarks of AGING
  2404. MicroRNAs and the metabolic hallmarks of AGING
  2405. The biology of AGING and cancer: a brief overview of shared and divergent molecular hallmarks
  2406. Molecular and physiological manifestations and measurement of AGING in humans
  2407. Mechanisms of lung AGING
  2408. Mitotic dysfunction associated with AGING hallmarks
  2409. Autophagy in stem cell AGING
  2410. The mitochondrial basis of AGING and age-related disorders
  2411. The intersection of AGING biology and the pathobiology of lung diseases: a joint NHLBI/NIA workshop
  2412. Direct reprogramming rather than iPSC-based reprogramming maintains AGING hallmarks in human motor neurons
  2413. Translational geroscience: A new paradigm for 21st century medicine
  2414. Recent advances in understanding Werner syndrome
  2415. Molecular and phenotypic biomarkers of AGING
  2416. Mechanisms linking AGING, diseases and biological age estimation
  2417. Protein posttranslational modifications: roles in AGING and age-related disease
  2418. Transcriptional signatures of AGING
  2419. The role of AGING in the development of osteoarthritis
  2420. Fueling inflamm-AGING through mitochondrial dysfunction: mechanisms and molecular targets
  2421. IPF lung fibroblasts have a senescent phenotype
  2422. Circadian Rhythms and Their Impact on AGING
  2423. Cancer and AGING-the inflammatory connection
  2424. Anti-AGING action of PPARs: Potential therapeutic targets
  2425. Role of mitochondrial metabolism in the control of early lineage progression and AGING phenotypes in adult hippocampal neurogenesis
  2426. Epigenetics and oxidative stress in AGING
  2427. Aspartic acid racemization on AGING
  2428. The system capacity view of AGING and longevity
  2429. Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human AGING
  2430. SPACEFLIGHT MIMICKS RAPID BONE AGING
  2431. Rejuvenation by partial reprogramming of the epigenome
  2432. AGING and Chronic Respiratory Diseases: Novel Mechanisms
  2433. Small Nucleoli and Reduced Ribosomal Biogenesis are Hallmarks of Longevity
  2434. Reproduction Onset Regulates a Collapse in a Broad Spectrum of AGING Hallmarks
  2435. Biphasic modeling of mitochondrial metabolism dysregulation during AGING
  2436. The potential role of intracellular heat shock protein 70 deficiency in AGING and pulmonary fibrosis
  2437. Cell and tissue biology paves a path to breast cancer prevention
  2438. Hormones of Hypothalamus in AGING
  2439. Senescence in COPD and its comorbidities
  2440. Molecular connections of AGING and cancer
  2441. Fleeting factors, turning back time
  2442. DNA-PK promotes the mitochondrial, metabolic, and physical decline that occurs during AGING
  2443. Mutation and catastrophe in the AGING genome
  2444. Mesenchymal stem cells for frailty?
  2445. A PATH FORWARD TO PREVENTING BREAST CANCER
  2446. Insulin-like growth factor 1: at the crossroads of brain development and AGING
  2447. How can AGING be thought of as anything other than a disease
  2448. Chronic Kidney Disease and Idiopathic Pulmonary Fibrosis: Thinking Outside the Box in Disease Management and Prognostication.
  2449. Osteomacs and bone regeneration
  2450. Geroscience and the trans-NIH geroscience interest group, GSIG
  2451. Collagen VI null mice as a model for early onset muscle decline in AGING
  2452. Dr. rer. nat. Michael Seimetz
  2453. Involvement of Klotho downregulation in radiation-induced senescence of renal epithelial cells
  2454. Stem cell transplantation for frailty
  2455. Environmental chemicals and AGING
  2456. Polyglutamine-expanded huntingtin exacerbates age-related disruption of nuclear integrity and nucleocytoplasmic transport
  2457. NAD+ in AGING: molecular mechanisms and translational implications
  2458. Metabolic regulation of angiogenesis in diabetes and AGING
  2459. The impacts of cellular senescence in elderly pneumonia and in age-related lung diseases that increase the risk of respiratory infections
  2460. Advanced glycation and AGING
  2461. Modulation of telomere protection by the PI3K/AKT pathway
  2462. UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST
  2463. Endoplasmic reticulum proteostasis impairment in AGING
  2464. AGING metabolism: intervention strategies
  2465. Telomere shortening, inflammatory cytokines, and anti-cytomegalovirus antibody follow distinct age-associated trajectories in humans
  2466. Biology of premature ageing in survivors of cancer
  2467. Pharynx mitochondrial [Ca2+] dynamics in live C. elegans worms during AGING
  2468. 2nd interventions in AGING conference
  2469. Biological predictors of AGING and potential of FTIR to study age-related diseases and AGING metabolic fingerprint
  2470. POSTTRANSLATIONAL MODULATION OF MACROMOLECULES DURING AGING
  2471. Therapeutic potential of systemic brain rejuvenation strategies for neurodegenerative disease
  2472. Starvation signals in yeast are integrated to coordinate metabolic reprogramming and stress response to ensure longevity
  2473. Biomarkers of AGING: from cellular senescence to age-associated diseases
  2474. Modelling age-associated diseases using transgenic progerin expression
  2475. Happily (n) ever after: AGING in the context of oxidative stress, proteostasis loss and cellular senescence
  2476. Xenohormesis in early life: New avenues of research to explore anti-AGING strategies through the maternal diet
  2477. T (ell) TALE signs of AGING
  2478. Biomarkers of AGING associated with past treatments in breast cancer survivors
  2479. Genome instability and AGING: Cause or effect?
  2480. Aged stem cells reprogram their daily rhythmic functions to adapt to stress
  2481. Physiology of ageing of the musculoskeletal system
  2482. AGING: somatic mutations, epigenetic drift and gene dosage imbalance
  2483. The decay of redox-stress response capacity is a substantive characteristic of AGING: revising the redox theory of AGING
  2484. The age-and sex-specific decline of the 20s proteasome and the Nrf2/CncC signal transduction pathway in adaption and resistance to oxidative stress in …
  2485. AGING and caloric restriction research: a biological perspective with translational potential
  2486. Will you still need me (Ca2+, TnT, and DHPR), will you still cleave me (calpain), when I’m 64?
  2487. Run regular, age slower, be neuroplastic
  2488. Regeneration of the AGING lung: a mini-review
  2489. Single-cell analysis of human pancreas reveals transcriptional signatures of AGING and somatic mutation patterns
  2490. Mitochondria in the spotlight of AGING and idiopathic pulmonary fibrosis
  2491. Epigenetic drift is a determinant of mammalian lifespan
  2492. The AGING population with HIV infection
  2493. Intercellular competition and the inevitability of multicellular AGING
  2494. Beneficial effects of antioxidative lactic acid bacteria
  2495. Geroprotectors: a unified concept and screening approaches
  2496. Calorie restriction breaks an epigenetic barrier to longevity
  2497. Alterations of the translation apparatus during AGING and stress response
  2498. Huntington’s disease: nuclear gatekeepers under attack
  2499. Red blood cell distribution width: genetic evidence for AGING pathways in 116,666 volunteers
  2500. Long live partial reprogramming
  2501. Regulation of stem cell AGING by metabolism and epigenetics
  2502. DNA Damage-related Vascular Dysfunction: Pathways and Interventions
  2503. The Atg8 family of proteins—modulating shape and functionality of autophagic membranes
  2504. Genome-wide transcriptomics of AGING in the rotifer Brachionus manjavacas, an emerging model system
  2505. Astrocyte elevated gene-1 (AEG-1) and the A (E) Ging HIV/AIDS-HAND
  2506. Human T cell immunosenescence and inflammation in AGING
  2507. The biology of AGING and cancer: frailty, inflammation, and immunity
  2508. Study on the Role of SIRT2 in Stem Cell AGING and Chronic Inflammation
  2509. A tissue engineered model of AGING: interdependence and cooperative effects in failing tissues
  2510. Insights into mortality patterns and causes of death through a process point of view model
  2511. Redox theory of AGING: implications for health and disease
  2512. InflammAGING and the lung
  2513. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs
  2514. Pulmonary Diseases, a Matter of Time
  2515. Maintained memory in AGING is associated with young epigenetic age
  2516. Effects of diet on telomere length: systematic review and meta-analysis
  2517. Cognitive decline in neuronal AGING and Alzheimer’s disease: role of NMDA receptors and associated proteins
  2518. Aged induced pluripotent stem cell (iPSCs) as a new cellular model for studying premature AGING
  2519. DNA methylation-based age prediction from various tissues and body fluids
  2520. Dissecting the molecular mechanisms that impair stress granule formation in AGING cells
  2521. Geropsychology: Mindfulness, stereotypes, and cognition in the AGING population.
  2522. Novel strategies for anti-AGING drug discovery
  2523. Integrins in senescence and AGING
  2524. Epigenetics of AGING and Longevity: Translational Epigenetics vol 4
  2525. The chromatin accessibility signature of AGING in human blood leukocytes stem from CD8+ T cells.
  2526. Analysis of senescence-related differentiation potentials and gene expression profiles in human dental pulp stem cells
  2527. AGING: molecular pathways and implications on the cardiovascular system
  2528. Inflammatory cytokines and comorbidity development in breast cancer survivors versus noncancer controls: evidence for accelerated AGING?
  2529. Lung diseases of the elderly: cellular mechanisms
  2530. The impact of cellular senescence in skin ageing: A notion of mosaic and therapeutic strategies
  2531. Licence to kill senescent cells in idiopathic pulmonary fibrosis?
  2532. Mitochondrial sirtuins and molecular mechanisms of AGING
  2533. The longitudinal study of AGING in human young adults: knowledge gaps and research agenda
  2534. Splicing regulatory factors, ageing and age-related disease
  2535. Metabolic adventures in AGING research
  2536. Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated AGING and diabetes
  2537. Septic shock and the AGING process: a molecular comparison
  2538. POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions
  2539. Circadian dysregulation and melatonin rhythm suppression in the context of AGING
  2540. Critical functions of the lysosome in cancer biology
  2541. Immune and inflammatory responses to DNA damage in cancer and AGING
  2542. Gerodontology: effects of ageing on the oral mucosa
  2543. Oncological challenges for an ageing population living with HIV
  2544. Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo
  2545. Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption
  2546. AGING, metabolism, and cancer development: from Peto’s paradox to the Warburg effect
  2547. Interplay of Hemolymph (HL) miRNA in The Regulation of AGING
  2548. The potential of iPSCs for the treatment of premature AGING disorders
  2549. Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
  2550. Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells
  2551. New Challenges—2017
  2552. Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the AGING brain
  2553. AGING in Rothmund-Thomson syndrome and related RECQL4 genetic disorders
  2554. AGING, exceptional longevity and comparisons of the Hannum and Horvath epigenetic clocks
  2555. Circadian reprogramming in the liver identifies metabolic pathways of AGING
  2556. DAF-16/FOXO transcription factor in AGING and longevity
  2557. Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species
  2558. SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
  2559. What modulates animal longevity? Fast and slow AGING in bivalves as a model for the study of lifespan
  2560. Healthy human AGING: intrinsic and environmental factors
  2561. Good Ol’fat: links between lipid signaling and longevity
  2562. Independent impacts of AGING on mitochondrial DNA quantity and quality in humans
  2563. The NAD+/PARP1/SIRT1 axis in AGING
  2564. Physiological links of circadian clock and biological clock of AGING
  2565. Mitochondria and epigenetics–crosstalk in homeostasis and stress
  2566. Functional relevance of miRNAs in premature ageing
  2567. MiRNA deregulation in cardiac AGING and associated disorders
  2568. Effects of testosterone administration on liver structure and function in AGING rats
  2569. Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
  2570. The Biology of AGING and Cancer
  2571. Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?
  2572. Frailty and anesthesia
  2573. Increased Arf/p53 activity in stem cells, AGING and cancer
  2574. Complex interplay between AGING and cancer: role of TGF-β signaling
  2575. Current perspective in the discovery of anti-AGING agents from natural products
  2576. Probiotic bacteria for healthier AGING: immunomodulation and metabolism of phytoestrogens
  2577. Theories and Mechanisms of AGING
  2578. The possible role of epigenetics in the memory impairment elicited by circadian rhythm disruption
  2579. Multigenerational silencing dynamics control cell AGING
  2580. Recognizing degenerative AGING as a treatable medical condition: methodology and policy
  2581. Embryonic stem cells: a novel paradigm to study proteostasis?
  2582. Mitochondrial ALDH2 deficiency promotes fibrosis and reactive oxygen species formation in the myocardium of aged mice
  2583. Geroprotectors: A Unified Concept and Screening Approaches
  2584. Circadian Clocks and mTOR Signaling
  2585. Human immunodeficiency virus and AGING in the era of effective antiretroviral therapy
  2586. Investigating the role of the CCT chaperonin in stem cell identity and AGING
  2587. Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury
  2588. Communication and the Normal AGING Process
  2589. Carbonyl toxification hypothesis of biological AGING
  2590. Current insights to regulation and role of telomerase in human diseases
  2591. Health benefits of late-onset metformin treatment every other week in mice
  2592. How can I protect my telomeres and slow AGING?
  2593. Physiological AGING: links among adipose tissue dysfunction, diabetes, and frailty
  2594. Single cell transcriptome analysis of human pancreas reveals transcriptional signatures of AGING and somatic mutation patterns
  2595. Visualization of AGING-associated chromatin alterations with an engineered TALE system
  2596. Exploring animal models that resemble idiopathic pulmonary fibrosis
  2597. Internal normalization of nascent RNA sequencing experiments to identify age-related changes of the mouse liver transcriptome
  2598. Alternative splicing in AGING and age-related diseases
  2599. Metabolic and genetic markers of biological age
  2600. AGING, metabolism and stem cells: Spotlight on muscle stem cells
  2601. Translating measures of biological AGING to test effectiveness of geroprotective interventions: what can we learn from research on telomeres?
  2602. miRNAs in stem cell AGING and age-related disease
  2603. Clearance of senescent cells: an immunotherapeutic approach
  2604. Genetics of AGING and longevity
  2605. Transcriptomic profiles of AGING in naïve and memory CD4+ cells from mice
  2606. Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
  2607. Epigenomics of human CD8 T cell differentiation and AGING
  2608. Note: Page numbers followed by f and t indicate figures and tables
  2609. Anti-ageing therapies in Alzheimer’s disease
  2610. Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders
  2611. GOLDEN anniversary of the acute respiratory distress syndrome: still much work to do!
  2612. Note: Page numbers followed by f and t indicate figures and tables respectivelyA
  2613. Functional relevance of miRNAs in premature ageing
  2614. Vitamins associated with brain AGING, mild cognitive impairment, and Alzheimer disease: Biomarkers, epidemiological and experimental evidence, plausible …
  2615. Rapamycin treatment attenuates age-associated periodontitis in mice
  2616. Caloric restriction improves health and survival of rhesus monkeys
  2617. The role of matrix metalloproteinases in AGING: Tissue remodeling and beyond
  2618. The changing face of AGING: highly sulfated glycosaminoglycans induce amyloid formation in a lattice corneal dystrophy model protein
  2619. Endoplasmic reticulum proteostasis impairment in AGING
  2620. TGH: Trans-Generational Hormesis and the Inheritance of AGING Resistance
  2621. Mechanistic overlap between chronic lung injury and cancer: ERS Lung Science Conference 2017 report
  2622. Detection of senescent cells by extracellular markers using a flow cytometry-based approach
  2623. Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal stem cells from differently aged donors
  2624. Endoplasmic reticulum proteostasis impairment in AGING
  2625. Towards a global initiative for fibrosis treatment (GIFT)
  2626. Age-related changes in bone marrow mesenchymal stromal cells: a potential impact on osteoporosis and osteoarthritis development
  2627. Generation of a Human Induced Pluripotent Stem Cell Based Model of Progerin Induced AGING
  2628. Biological and Social Theories of AGING
  2629. The citrus flavanone naringenin protects myocardial cells against age-associated damage
  2630. Chronicle of a Neuronal Death Foretold: Preventing AGING by Keeping MGRN1 at the Nucleus
  2631. Biomechanical strain exacerbates inflammation on a progeria‐on‐a‐chip model
  2632. Retinal, NPY-and 5 ht-inputs to the aged suprachiasmatic nucleus in common marmosets (Callithrix jacchus)
  2633. The AGING cardiovascular system: understanding it at the cellular and clinical levels
  2634. The Role Of Intracellular Heat Shock Protein 70 Deficiency In Idiopathic Pulmonary Fibrosis
  2635. Keeping up with the Red Queen: the pace of AGING as an adaptation
  2636. Sarcopenia: causes and treatments
  2637. Chronic inflammation in immune AGING: role of pattern recognition receptor crosstalk with the telomere complex?
  2638. Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives
  2639. The Endocrinology of AGING: a key to longevity “Great Expectations”
  2640. Blue light-induced oxidative stress in live skin
  2641. Nucleolar expansion and elevated protein translation in premature AGING
  2642. Cytokine-induced senescence for cancer surveillance
  2643. Chemical screening identifies ATM as a target for alleviating senescence
  2644. The role of epigenetics in renal ageing
  2645. The potential role of senescence as a modulator of platelets and tumorigenesis
  2646. Age-related changes in plasma extracellular vesicle characteristics and internalization by leukocytes
  2647. Red Blood Cell Distribution Width: genetic evidence for AGING pathways in 116,666 volunteers
  2648. Telomere-driven diseases and telomere-targeting therapies
  2649. SELECTED THEORIES OF AGEING
  2650. 2 Understanding AGING
  2651. HIV-associated cellular senescence: a contributor to accelerated AGING
  2652. Unveiling the role of senescence-induced cellular plasticity
  2653. NAD and the AGING process: Role in life, death and everything in between
  2654. Studying the geroprotective effects of inhibitors suppressing AGING-associated signaling cascades in model organisms
  2655. A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans
  2656. Eco-AGING: stem cells and microbes are controlled by AGING antagonist FoxO
  2657. Increased genome instability is not accompanied by sensitivity to DNA damAGING agents in aged yeast cells
  2658. Using comparative biology to understand how AGING affects mitochondrial metabolism
  2659. New approach to generating insights for AGING research based on literature mining and knowledge integration
  2660. The clinical potential of senolytic drugs
  2661. AGING Schwann cells: mechanisms, implications, future directions
  2662. Microglia priming with AGING and stress
  2663. Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline
  2664. Role of circulating factors in cardiac AGING
  2665. Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells
  2666. The origin of life at the origin of ageing?
  2667. Physical exercise as an effective antiAGING intervention
  2668. Mitochondrial dysfunction in pulmonary fibrosis
  2669. Bloom’s syndrome: Why not premature AGING?: A comparison of the BLM and WRN helicases
  2670. Molecular chaperone accumulation in cancer and decrease in Alzheimer’s disease: the potential roles of HSF1
  2671. Inflammation and premature AGING in advanced chronic kidney disease
  2672. Hepatic S6K1 partially regulates lifespan of mice with mitochondrial complex I deficiency
  2673. Three‐year changes in physical activity and decline in physical performance over 9 years of follow‐up in older adults: the invecchiare in Chianti study
  2674. Energy metabolism and ageing in the mouse: a mini-review
  2675. Regulation of TERRA on telomeric and mitochondrial functions in IPF pathogenesis
  2676. Ginsenoside Rg3 prevents oxidative stress-induced astrocytic senescence and ameliorates senescence paracrine effects on glioblastoma
  2677. Methylation of the ribosomal RNA gene promoter is associated with AGING and age‐related decline
  2678. 18 Manipulating AGING to Treat
  2679. MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice
  2680. Are there any biomarkers of AGING? Biomarkers of the brain
  2681. Ageing and ocular surface immunity
  2682. Arginase-II deficiency extends lifespan in mice
  2683. Changes of protein turnover in AGING Caenorhabditis elegans
  2684. Cellular senescence, immunosenescence and HIV
  2685. ANGPTL2―A New Causal Player in Accelerating Heart Disease Development in the AGING―
  2686. Epigenetic mechanisms underlying lifespan and age-related effects of dietary restriction and the ketogenic diet
  2687. Coupling Protein Catabolism to Lifespan and Reproduction in Caenorhabditis elegans
  2688. Improving mitochondrial function significantly reduces metabolic, visual, motor and cognitive decline in aged Drosophila melanogaster
  2689. Does eating less make you live longer and better? An update on calorie restriction
  2690. Conserved and species-specific molecular denominators in mammalian skeletal muscle AGING
  2691. Masters athletes: Exemplars of successful AGING?
  2692. Proteostatic and metabolic control of stemness
  2693. Life stress, glucocorticoid signaling, and the AGING epigenome: implications for AGING-related diseases
  2694. Interaction between epigenetic and metabolism in AGING stem cells
  2695. Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle
  2696. Impact of yoga and meditation on cellular AGING in apparently healthy individuals: a prospective, open-label single-arm exploratory study
  2697. Age-associated DNA methylation changes in naive CD4+ T cells suggest an evolving autoimmune epigenotype in AGING T cells
  2698. Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically AGING …
  2699. Molecular signatures of longevity: insights from cross-species comparative studies
  2700. D108 CELL FATE DECISIONS: SENESCENCE, REPAIR, AND REGENERATION: Mitochondrial Uncoupling Protein-2 Mediates Fibroblast Senescence In Age …
  2701. Hexokinases link DJ-1 to the PINK1/parkin pathway
  2702. The UPRER: sensor and coordinator of organismal homeostasis
  2703. Mitochondrial Uncoupling Protein-2 Mediates Fibroblast Senescence In Age-Related Lung Fibrosis
  2704. Predicting age by mining electronic medical records with deep learning characterizes differences between chronological and physiological age
  2705. Interleukin-7 and immunosenescence
  2706. Integrin beta 3 regulates cellular senescence by activating the TGF-β pathway
  2707. Common methods of biological age estimation
  2708. Absence of correlation between chimeric RNA and AGING
  2709. A null mutation in SERPINE1 protects against biological AGING in humans
  2710. Restoring pharmacologic preconditioning in the AGING heart: role of mitophagy/autophagy
  2711. Cognitive functions and neurotropic factors associated with AGING: A review
  2712. Mitogen-activated protein kinases, Fus3 and Kss1, regulate chronological lifespan in yeast
  2713. Emerging candidate treatment strategies for Hutchinson-Gilford progeria syndrome
  2714. Protective effects of short-term dietary restriction in surgical stress and chemotherapy
  2715. Commentary: The ageing as a therapeutic target for Alzheimer’s disease
  2716. The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
  2717. Mitophagy in neurodegeneration and AGING
  2718. Modulation of the senescence-associated inflammatory phenotype in human fibroblasts by olive phenols
  2719. Lifelong dietary intervention does not affect hematopoietic stem cell function
  2720. Nutrient sensing pathways as therapeutic targets for healthy ageing
  2721. Multi-protection of DL0410 in ameliorating cognitive defects in D-galactose induced AGING mice
  2722. Neurobiology of sleep and microbiomics in AGING
  2723. Mitochondria deliver a gut check to intestinal stem cells
  2724. 6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence …
  2725. TERT promoter mutations in telomere biology
  2726. Mechanisms underlying the essential role of mitochondrial membrane lipids in yeast chronological AGING
  2727. Targeting chromatin AGING-The epigenetic impact of longevity-associated interventions
  2728. FOXO transcriptional factors and long-term living
  2729. Quantitative and systems pharmacology 3. Network-based identification of new targets for natural products enables potential uses in AGING-associated …
  2730. Dietary protein, AGING and nutritional geometry
  2731. The companion dog as a unique translational model for AGING
  2732. Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and AGING
  2733. The effects of AGING on platelet bioenergetics
  2734. 3-year changes in physical activity and physical performance decline over 9 years of follow-up in older adults: The InCHIANTI study
  2735. Role of pattern recognition receptors of the neurovascular unit in inflamm-AGING
  2736. Sirt1 and Parp1 as epigenome safeguards and microRNAs as SASP-associated signals, in cellular senescence and AGING
  2737. Back and forth in time: Directing age in iPSC-derived lineages
  2738. The epigenetic landscape of age-related diseases: the geroscience perspective
  2739. Rhodiola rosea L.: an herb with anti-stress, anti-AGING, and immunostimulating properties for cancer chemoprevention
  2740. Exposure to Concentrated Ambient PM2.5 Shortens Lifespan and Induces Inflammation-Associated Signaling and Oxidative Stress in Drosophila
  2741. Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro
  2742. Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans
  2743. Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the AGING brain
  2744. The effect of polyphenols on protein degradation pathways: implications for neuroprotection
  2745. Ochratoxin A induced premature senescence in human renal proximal tubular cells
  2746. Transcriptional profiling reveals protective mechanisms in brains of long-lived mice
  2747. Integrating frailty research into the medical specialties—report from a U13 conference
  2748. AGING asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri
  2749. Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation
  2750. Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity
  2751. Glutaminolysis: a hallmark of cancer metabolism
  2752. Knockout of vasohibin-1 gene in mice results in healthy longevity with reduced expression of insulin receptor, insulin receptor substrate 1, and insulin receptor …
  2753. Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment
  2754. Report: NIA workshop on measures of physiologic resiliencies in human AGING
  2755. Muscle stem cells: a model system for adult stem cell biology
  2756. What have we learned on AGING from omics studies?
  2757. Baicalein Exerts Beneficial Effects in d-Galactose-Induced AGING Rats Through Attenuation of Inflammation and Metabolic Dysfunction
  2758. Transcriptomic network analysis of brain AGING and alzheimers disease
  2759. Patients with gout have short telomeres compared with healthy participants: association of telomere length with flare frequency and cardiovascular disease in gout
  2760. Validation of minimally-invasive sample collection methods for measurement of telomere length
  2761. Deletion of mitochondrial inorganic pyrophosphatase gene extends life span in haploid yeast (Saccharomyces cerevisiae)
  2762. Rejuvenation of cardiac tissue developed from reprogrammed aged somatic cells
  2763. Role of estrogen and other sex hormones in brain AGING. Neuroprotection and DNA repair
  2764. AGING and sarcopenia associate with specific interactions between gut microbes, serum biomarkers and host physiology in rats
  2765. The association between post-traumatic stress disorder and shorter telomere length: a systematic review and meta-analysis
  2766. The role of cancer-associated fibroblasts and fibrosis in liver cancer
  2767. AGING: Fewer Obstacles to DNA Replication?
  2768. SIRT1 overexpression in mouse hippocampus induces cognitive enhancement through proteostatic and neurotrophic mechanisms
  2769. Membrane damage by betulinic acid provides insights into cellular AGING
  2770. Mitochondrial AGING: is there a mitochondrial clock?
  2771. Sedentary behavior, physical activity and cardiorespiratory fitness on leukocyte telomere length
  2772. Age-Related Dysfunction in Lung Barrier Function in Health and Disease: Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related …
  2773. AGING and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca 2+ responses, and neuron cell death in cultured rat hippocampal neurons
  2774. Long noncoding RNAs and RNA-binding proteins in oxidative stress, cellular senescence, and age-related diseases
  2775. Implantation of cryopreserved human placental fragments restores prooxidant-antioxidant balance in experimental animals of late ontogeny
  2776. Bone microRNAs and ageing
  2777. Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis
  2778. From one syndrome to many: incorporating geriatric consultation into HIV care
  2779. HDAC6 suppresses age-dependent ectopic fat accumulation by maintaining the proteostasis of PLIN2 in Drosophila
  2780. Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular AGING to cell cycle regulation, maintenance of a quiescent state, entry …
  2781. Comparative analysis of oxidative stress during AGING of Kluyveromyces marxianus in synthetic and whey media
  2782. Extracellular RNA in AGING
  2783. Uncoupling of metabolic health from longevity through genetic alteration of adipose tissue lipid-binding proteins
  2784. Inflammation and cognition in older adults: evidence from Taiwan
  2785. Oogenesis, vitellogenin-mediated ovarian degeneration and immune response in the annual fish Nothobranchius guentheri
  2786. Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological AGING
  2787. AGING and immortality in unicellular species
  2788. Clock mediates liver senescence by controlling ER stress
  2789. Mesenchymal stem cell-based cartilage regeneration approach and cell senescence: can we manipulate cell AGING and function?
  2790. Techniques used for determination of Biological Age.
  2791. Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice
  2792. Intranasal cerebrolysin attenuates learning and memory impairments in D-galactose-induced senescence in mice
  2793. Epigenetic AGING signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment
  2794. Small heat shock proteins in ageing and age-related diseases
  2795. Circulating markers of ageing and allostatic load: a slow train coming
  2796. Ras signaling in AGING and metabolic regulation
  2797. Mitochondrial dynamics: coupling mitochondrial fitness with healthy AGING
  2798. Synergistic effect of rapamycin and metformin against age-dependent oxidative stress in rat erythrocytes
  2799. SASP regulation by noncoding RNA
  2800. Mitochondria in cell senescence: is mitophagy the weakest link?
  2801. Comparison of intermittent fasting versus caloric restriction in obese subjects: A two year follow-up
  2802. Telomere length in elite athletes
  2803. Glucose transporter 1–dependent glycolysis is increased during AGING-related lung fibrosis, and phloretin inhibits lung fibrosis
  2804. Antagonistic pleiotropy and mutation accumulation influence human senescence and disease
  2805. Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular AGING
  2806. Development and diabetes on the fly
  2807. Reactive oxygen species as signaling molecules in the development of lung fibrosis
  2808. Tocotrienol-Rich Fraction Supplementation Improves the Quality of Oocytes and Maintains Telomere Length in Ovaries from AGING Mice
  2809. Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
  2810. Autophagy is pro-senescence when seen in close-up, but anti-senescence in long-shot
  2811. Cellular regulation of amyloid formation in AGING and disease
  2812. Regulation of stem cell AGING by SIRT1–Linking metabolic signaling to epigenetic modifications
  2813. Endogenous stem cells in homeostasis and AGING
  2814. Mental retirement and health selection: Analyses from the US Health and Retirement Study
  2815. Can we rejuvenate? Implications of biological AGING research
  2816. Time-dependent genetic effects on gene expression implicate AGING processes
  2817. Saccharomyces cerevisiae as a Model to Confirm the Ability of FTIR to Evaluate the Presence of Protein Aggregates
  2818. Promising links between meditation and reduced (brain) AGING: an attempt to bridge some gaps between the alleged fountain of youth and the youth of the …
  2819. The association between Alu hypomethylation and severity of type 2 diabetes mellitus
  2820. Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing
  2821. Lymphangioleiomyomatosis: a monogenic model of malignancy
  2822. FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres
  2823. Drug-induced premature senescence model in human dental follicle stem cells
  2824. Tat-mediated induction of miRs-34a &-138 promotes astrocytic activation via downregulation of SIRT1: implications for AGING in HAND
  2825. Sleep apnea: a geriatric syndrome
  2826. Polyunsaturated fatty acids ameliorate AGING via redox-telomere-antioncogene axis
  2827. Purification and antioxidant activity of phycocyanin from Synechococcus sp. R42DM isolated from industrially polluted site
  2828. P49/STRAP, a serum response factor binding protein (SRFBP1), is involved in the redistribution of cytoskeletal f-actin proteins during glucose deprivation
  2829. Anti-AGING effect of riboflavin via endogenous antioxidant in fruit fly Drosophila melanogaster
  2830. AGING modifies daily variation of antioxidant enzymes and oxidative status in the hippocampus
  2831. Emerging molecular pathways governing dietary regulation of neural stem cells during AGING
  2832. Current Perspective in the Discovery of Anti-AGING Agents from Natural Products
  2833. The concept of ageing in evolutionary algorithms: discussion and inspirations for human ageing
  2834. Mitochondrial gene polymorphism is associated with gut microbial communities in mice
  2835. Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities
  2836. Basic biology of oxidative stress and the cardiovascular system: part 1 of a 3-part series
  2837. Investigating the Relationship Between DNA Damage and Hormesis in Saccharomyces cerevisiae Chronological AGING
  2838. Apoptosis in the AGING liver
  2839. Age-related changes in locomotor performance reveal a similar pattern for Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo …
  2840. AGING as an epigenetic phenomenon
  2841. The chromatin accessibility signature of human immune AGING stems from CD8+ T cells
  2842. Immunoproteasomes control the homeostasis of medullary thymic epithelial cells by alleviating proteotoxic stress
  2843. Proteomics and metabolomics in ageing research: from biomarkers to systems biology
  2844. From rapalogs to anti-AGING formula
  2845. Autophagy and microglia: novel partners in neurodegeneration and AGING
  2846. Predicting age using neuroimAGING: innovative brain ageing biomarkers
  2847. Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster
  2848. Osteoarthritis: toward a comprehensive understanding of pathological mechanism
  2849. Biomarkers of AGING: From Cellular Senescence to Age-Associated Diseases
  2850. Nuclear ubiquitin C-terminal hydrolase L5 expression associates with increased patient survival in pancreatic ductal adenocarcinoma
  2851. Mitochondrial function and mitophagy in the elderly: effects of exercise
  2852. Changing mutational and adaptive landscapes and the genesis of cancer
  2853. Cryopreserved Placental Explants Increase Lifespan of Male Mice and Change Survival Features of Female Mice
  2854. Gene therapy with the TRF 1 telomere gene rescues decreased TRF 1 levels with AGING and prolongs mouse health span
  2855. Landscape of genome-wide age-related DNA methylation in breast tissue
  2856. The fountain of youth by targeting senescent cells?
  2857. Isolation and identification of senescent renal tubular epithelial cells using immunomagnetic beads based on DcR2
  2858. AGING and the Krüppel-like factors
  2859. Nucleosome remodelling, DNA repair and transcriptional regulation build negative feedback loops in cancer and cellular ageing
  2860. Impact of age, caloric restriction, and influenza infection on mouse gut microbiome: an exploratory study of the role of age-related microbiome changes on …
  2861. Peroxiredoxins in Redox Signaling and AGING
  2862. Endocrinology of cancer and age: Early and late developmental stages
  2863. Paradoxical AGING in HIV: immune senescence of B Cells is most prominent in young age
  2864. Significance of miR-146a quantification in human blood plasma for the diagnosis of colorectal cancer
  2865. Biological and clinical implications of telomere dysfunction in myeloid malignancies
  2866. Mitochondrial stress restores the heat shock response and prevents proteostasis collapse during AGING
  2867. Effects of resveratrol and other polyphenols on the most common brain age-related diseases
  2868. Interstitial lung abnormalities and AGING
  2869. Longevity is impacted by growth hormone action during early postnatal period
  2870. Interleukin-6 affects AGING-related changes of the pparα-PGC-1α axis in the myocardium
  2871. Cellular senescence is associated with human retinal microaneurysm formation during AGING
  2872. Inflammatory long pentraxin 3 is associated with leukocyte telomere length in night-shift workers
  2873. Functionally and morphologically damaged mitochondria observed in auditory cells under senescence-inducing stress
  2874. SuperAgers: do octogenarians with exceptional memory hold the key to healthy AGING?
  2875. Old age causes de novo intracortical bone remodeling and porosity in mice
  2876. Senescence-inflammatory regulation of reparative cellular reprogramming in AGING and cancer
  2877. β-Hydroxybutyrate deactivates neutrophil NLRP3 inflammasome to relieve gout flares
  2878. Sofie Degerman1, Maria Josefsson2, Annelie Nordin Adolfsson3, Sigrid Wennstedt1, Mattias Landfors1
  2879. Topoisomerase IIβ and its role in different biological contexts
  2880. Enhanced molecular AGING in late-life depression: the senescent-associated secretory phenotype
  2881. Changing direction: From therapeutic telomerase inhibition to activation?
  2882. NAD+ deficits in age-related diseases and cancer
  2883. Metabolic roles of poly (ADP-ribose) polymerases
  2884. Licorice extract attenuates brain AGING of d-galactose induced rats through inhibition of oxidative stress and attenuation of neuronal apoptosis
  2885. High plasticity of new granule cells in the AGING hippocampus
  2886. Cardiac and systemic rejuvenation after cardiosphere-derived cell therapy in senescent rats
  2887. Mitochondrial-targeted catalase: extended longevity and the roles in various disease models
  2888. Evaluation of respiratory function in physically active elderly males in comparison to males having sedentary lifestyle
  2889. Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
  2890. The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age
  2891. Dysfunction of the MDM2/p53 axis is linked to premature AGING
  2892. Geriatric syndromes: new frontiers in HIV and sarcopenia
  2893. P16 INK4a deletion ameliorated renal tubulointerstitial injury in a stress-induced premature senescence model of Bmi-1 deficiency
  2894. Role of kallistatin treatment in AGING and cancer by modulating miR-34a and miR-21 expression
  2895. Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE
  2896. Nutrients in energy and one-carbon metabolism: learning from metformin users
  2897. Exercise and bone health across the lifespan
  2898. Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice
  2899. TOR‐mediated regulation of metabolism in AGING
  2900. Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy
  2901. Critically short telomeres and toxicity of chemotherapy in early breast cancer
  2902. Age-dependent obesity and mitochondrial dysfunction
  2903. Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts
  2904. Remodeling of the extracellular matrix in COPD. a process of accelerated lung ageing?
  2905. Oxidative Stress in Mesenchymal Stem Cell Senescence: Regulation by Coding and Noncoding RNAs. Antioxidants and Redox Signaling, 29 (9), 864-879 …
  2906. Molecular chaperones in neurodegenerative diseases: a short review
  2907. Molecular mechanisms determining lifespan in short-and long-lived species
  2908. Nutrition in early life and age-associated diseases
  2909. Getting old through the blood: Circulating molecules in AGING and senescence of cardiovascular regenerative cells
  2910. Regulation of metabolic health and AGING by nutrient-sensitive signaling pathways
  2911. Clock-enhancing small molecules and potential applications in chronic diseases and AGING
  2912. Effects of physical activity on the cerebral networks
  2913. Differential and correlated expressions of p16/p21/p27/p38 in mammary gland tumors of aged dogs
  2914. Erratum to “Impact of yoga and meditation on cellular AGING in apparently healthy individuals: a prospective, open-label single-arm exploratory study”
  2915. Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy
  2916. High sensitivity of human adipose stem cells to differentiate into myofibroblasts in the presence of C. aspersa egg extract
  2917. Modern biotechnological approaches to lifespan extension of animals and humans
  2918. Social isolation in the elderly; Physical Activity to the Rescue
  2919. Cancer—incidence, prevalence and mortality in the oldest-old. A comprehensive review
  2920. A reduction in DNA damage in neural tissue and peripheral blood of old mice treated with caffeine
  2921. MOAG-4 promotes the aggregation of α-synuclein by competing with self-protective electrostatic interactions
  2922. Biosystems Study of the Molecular Networks Underlying Hippocampal AGING Progression and Anti-AGING Treatment in Mice
  2923. Allogeneic mesenchymal stem cells ameliorate AGING frailty: a phase II randomized, double-blind, placebo-controlled clinical trial
  2924. Biophysical and biomolecular determination of cellular age in humans
  2925. Interventions to support healthy eating in later life
  2926. Greater cortical thickness in elderly female yoga practitioners—a cross-sectional study
  2927. Potential therapeutic effects of lipoic acid on memory deficits related to AGING and neurodegeneration
  2928. Neuroprotective functions for the histone deacetylase SIRT6
  2929. King’s Research Portal
  2930. Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4
  2931. How endothelial cells adapt their metabolism to form vessels in tumors
  2932. miRNA-34b is directly involved in the AGING of macrophages
  2933. Mitochondrial metabolism-mediated regulation of adult neurogenesis
  2934. IRE1 signaling exacerbates Alzheimer’s disease pathogenesis
  2935. Pachymic acid promotes induction of autophagy related to IGF-1 signaling pathway in WI-38 cells
  2936. BAG2 interferes with CHIP-mediated ubiquitination of HSP72
  2937. Autophagy in the presynaptic compartment in health and disease
  2938. Pro-and antioxidant functions of the peroxisome-mitochondria connection and its impact on AGING and disease
  2939. NutrimiRAGING: micromanAGING nutrient sensing pathways through nutrition to promote healthy AGING
  2940. Cellular senescence in age-related macular degeneration: can autophagy and DNA damage response play a role?
  2941. D-galactose-induced brain ageing model: a systematic review and meta-analysis on cognitive outcomes and oxidative stress indices
  2942. Lung cancer in patients with idiopathic pulmonary fibrosis
  2943. Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice
  2944. Genome and epigenome editing in mechanistic studies of human AGING and AGING-related disease
  2945. miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1
  2946. Allogeneic human mesenchymal stem cell infusions for AGING frailty
  2947. Parabiosis and AGING Researches
  2948. Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over time
  2949. Unmasking transcriptional heterogeneity in senescent cells
  2950. Human induced pluripotent stem cells illuminate pathways and novel treatment targets for age-related macular degeneration
  2951. Assessment of the AGING of the brown adipose tissue by 18F-FDG PET/CT imAGING in the progeria mouse model LmnaG609G/G609G
  2952. Metformin reduces the rate of small intestinal glucose absorption in type 2 diabetes
  2953. Psychological Stress and Cellular AGING
  2954. Herba Cistanches: anti-AGING
  2955. Mechanisms of three-dimensional transcriptional regulation in cell senescence
  2956. Yeast models of Parkinson’s disease-associated molecular pathologies
  2957. Vitamin E supplementation reduces cellular loss in the brain of a premature AGING mouse model
  2958. Calorie restriction effects on circadian rhythms in gene expression are sex dependent
  2959. Calorie restriction in rodents: caveats to consider
  2960. Cytochrome P450-2E1 is involved in AGING-related kidney damage in mice through increased nitroxidative stress
  2961. Modulatory effects of Decalepis hamiltonii extract and its compounds on the antioxidant status of the AGING rat brain
  2962. Pleiotropic responses to methionine restriction
  2963. Minocycline treatment increases resistance to oxidative stress and extends lifespan in Drosophila via FOXO
  2964. CAN1 arginine permease deficiency extends yeast replicative lifespan via translational activation of stress response genes
  2965. The genetics of human longevity: an intricacy of genes, environment, culture and microbiome
  2966. Autophagy maintains the metabolism and function of young and old stem cells
  2967. GPR56 as a Potential Regulator of Human Normal and Leukemic Stem Cells
  2968. 2, 3-Dehydrosilybin A/B as a pro-longevity and anti-aggregation compound
  2969. Multiple roles for the MLL/COMPASS family in the epigenetic regulation of gene expression and in cancer
  2970. Cryptomphalus aspersa mollusc egg extract promotes regenerative effects in human dermal papilla stem cells
  2971. Effects of rapamycin on life span and on expression of TOR and S6K in Brachionus calyciflorus (Rotifera)
  2972. DIZZINESS AND ITS ASSOCIATED FACTORS IN GERIATRIC POPULATION IMPACTING FUNCTIONAL AND PSYCHOLOGICAL STATUS
  2973. Sirtuins and DNA damage repair: SIRT7 comes to play
  2974. AGING and Vasoreactivity
  2975. AGING and Dieting: an overview of dietary interventions and their role in lifespan and health span
  2976. Nampt expression decreases age-related senescence in rat bone marrow mesenchymal stem cells by targeting Sirt1
  2977. Epithelial autophagy and longevity of Hydra oligactis, a new model for AGING research
  2978. On somatic constraints in the evolution of multicellularity
  2979. Novel Metabolites that Modulate AGING and AGING-related Symptoms
  2980. Cancer-related cognitive impairment in older adults
  2981. Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition
  2982. Age and gender alter synaptic proteins in zebrafish (Danio Rerio) models of normal and delayed AGING
  2983. Physical activity and the effect of multimorbidity on all-cause mortality in older adults
  2984. Multi-tissue DNA methylation age predictor in mouse
  2985. Mitochondria, Cybrids, AGING, and Alzheimer’s disease
  2986. The relationship of survivorship and body mass modeled by metabolic and vitality theories
  2987. Epigenetic treatment of neurodegenerative ophthalmic disorders: an eye toward the future
  2988. Oxidative status predicts quality in human mesenchymal stem cells
  2989. A life-long approach to physical activity for brain health
  2990. Nucleolus association of chromosomal domains is largely maintained in cellular senescence despite massive nuclear reorganisation
  2991. Cancer epigenetics
  2992. Mechanisms of oncogene-induced genomic instability
  2993. Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort
  2994. The addition of a developmental factor, unc-62, to already long-lived worms increases lifespan and healthspan
  2995. Hormetic induction of antioxidant defenses for promotion of healthy AGING
  2996. Age-associated molecular changes are deleterious and may modulate life span through diet
  2997. AGING-associated dysbiosis increases susceptibility to enteric viral infection in Drosophila
  2998. Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism
  2999. A progressive reduction in autophagic capacity contributes to induction of replicative senescence in Hs68 cells
  3000. AGING results in a decline in cellular energy metabolism in the trophocytes and oenocytes of worker honeybees (Apis mellifera)
  3001. Dictyostelium discoideum: A Model System to Study Autophagy Mediated Life Extension
  3002. Proteomic analysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response
  3003. Lung remodeling in AGING surfactant protein D deficient mice
  3004. Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7
  3005. What do we mean by older adult and physical activity? Reviewing the use of these terms in recent research
  3006. From Sarcopenia to Frailty: the pathophysiological basis and potential target molecules of intervention
  3007. Proteostatic and metabolic control of stemness
  3008. Human health and AGING over an infinite time horizon
  3009. Non-coding RNA molecules connect calorie restriction and lifespan
  3010. Differential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegans
  3011. Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells
  3012. Formal models of biological systems
  3013. A review of supervised machine learning applied to ageing research
  3014. Distribution pattern following systemic mesenchymal stem cell injection depends on the age of the recipient and neuronal health
  3015. Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults
  3016. Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants
  3017. Dietary restriction and AMPK increase lifespan via mitochondrial network and peroxisome remodeling
  3018. 3β-Hydroxy-urs-12-en-28-oic Acid Modulates Dietary Restriction Mediated Longevity and Ameliorates Toxic Protein Aggregation in C. elegans
  3019. Successful and maladaptive T cell AGING
  3020. Sleep variability among older adults with insomnia: associations with sleep quality and cardiometabolic disease risk
  3021. Frailty in older adults
  3022. Omics approaches for identifying physiological adaptations to genome instability in AGING
  3023. Proteostasis of huntingtin in health and disease
  3024. Pathogenesis of COPD 4–Cell Death, Senescence, and Autophagy: Is There a Possibility of Developing New Drugs from the Standpoint of This Pathogenetic …
  3025. Estimating influenza vaccine effectiveness: evolution of methods to better understand effects of confounding in older adults
  3026. Characterization and Modeling of Metabolic Stress Responses in Cellular AGING
  3027. Vascular smooth muscle cells and arterial stiffening: relevance in development, AGING, and disease
  3028. An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo
  3029. Sex-specific lifespan and its evolution in nematodes
  3030. Olive Oil polyphenols can be Useful to Prevent AGING-Associated Neurodegeneration
  3031. Telomere-driven diseases and telomere-targeting therapies
  3032. Parity history determines a systemic inflammatory response to spread of ovarian cancer in naturally aged mice
  3033. Caloric Restriction, Sirtuins, and Ageing
  3034. Analyzing tumor metabolism in vivo
  3035. Anesthetic isoflurane induces DNA damage through oxidative stress and p53 pathway
  3036. From lymphopoiesis to plasma cells differentiation, the age-related modifications of B cell compartment are influenced by “inflamm-ageing”
  3037. Signaling and immune regulation in melanoma development and responses to therapy
  3038. Anticancer effects of the microbiome and its products
  3039. Design, synthesis of allosteric peptide activator for human SIRT1 and its biological evaluation in cellular model of Alzheimer’s disease
  3040. Noncoding RNA in cancer
  3041. Sarcopenic obesity, weight loss, and mortality: the English Longitudinal Study of Ageing
  3042. The emerging role of Wnt signaling dysregulation in the understanding and modification of age-associated diseases
  3043. Metabolic and Genetic Markers of Biological Age. Front. Genet. 8: 64. doi: 10.3389/fgene. 2017.00064 Metabolic and Genetic Markers of Biological Age S …
  3044. Overcoming immune dysregulation with immunoengineered nanobiomaterials
  3045. Proteostasis in cardiac health and disease
  3046. Long-term calorie restriction in humans is not associated with indices of delayed immunologic AGING: a descriptive study
  3047. Changes in the mitochondrial function and in the efficiency of energy transfer pathways during cardiomyocyte AGING
  3048. Mortality is associated with inflammation, anemia, specific diseases and treatments, and molecular markers
  3049. Non-Thermal Atmospheric Pressure Plasma Enhances Proliferation of Adipose Tissue-Derived Stem Cells via Nitric Oxide-Response Pathways
  3050. Amalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy
  3051. Expression profiling of mRNAs and long non-coding RNAs in aged mouse olfactory bulb
  3052. Extended multiplexing of tandem mass tags (TMT) labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue
  3053. Antioxidant defence, oxidative stress and oxidative damage in saliva, plasma and erythrocytes of dementia patients. Can salivary AGE be a marker of dementia?
  3054. NMR studies reveal that protein dynamics critically mediate aggregation of the well-folded and very soluble E. coli S1 ribosomal protein
  3055. Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
  3056. Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase
  3057. Secrets from immortal worms: what can we learn about biological ageing from the planarian model system?
  3058. Influence of resistance training in quality of life, body composition, and physical performance of community-dwelling elderly women
  3059. Tissue-, sex-, and age-specific DNA methylation of rat glucocorticoid receptor gene promoter and insulin-like growth factor 2 imprinting control region
  3060. Convergent adaptation of cellular machineries in the evolution of large body masses and long life spans
  3061. The role of mitochondria in the myocardium of senescent Meriones unguiculates
  3062. The role of Nrf2 in cardiovascular function and disease
  3063. The ubiquitin ligase CHIP integrates proteostasis and AGING by regulation of insulin receptor turnover
  3064. Blood to Blood: A New Therapeutic Opportunity for Age-Related Diseases
  3065. Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice
  3066. Changes in the lethality of frailty over 30 years: evidence from two cohorts of 70-year-olds in Gothenburg Sweden
  3067. LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis
  3068. Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts
  3069. Unfolded protein response of the endoplasmic reticulum in tumor progression and immunogenicity
  3070. Sex matters: The effects of biological sex on adipose tissue biology and energy metabolism
  3071. Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects
  3072. Jaws and Dental Panoramic Radiographic Findings in the Elderly in Kerman, Iran
  3073. Evolutionary perspectives on ageing
  3074. Determinants and regulation of protein turnover in yeast
  3075. Perceived consequences of ageing with late effects of polio and strategies for manAGING daily life: a qualitative study
  3076. SIRT6 overexpression improves various aspects of mouse healthspan
  3077. Standardized Kaempferia parviflora extract inhibits intrinsic AGING process in human dermal fibroblasts and hairless mice by inhibiting cellular senescence …
  3078. Cofactors as metabolic sensors driving cell adaptation in physiology and disease
  3079. Fish oil diet may reduce inflammatory levels in the liver of middle-aged rats
  3080. α-Synuclein pathology and mitochondrial dysfunction
  3081. Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate
  3082. Plasticity of Antioxidant Defense Pathways in Response to AGING and Cadmium in Glutathione-Deficient Mice
  3083. Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?
  3084. High volume exercise training in older athletes influences inflammatory and redox responses to acute exercise
  3085. The role of the nuclear envelope protein man1 in mesenchymal stem cell differentiation
  3086. Jujube (Ziziphus Jujuba Mill.) fruit feeding extends lifespan and increases tolerance to environmental stresses by regulating AGING-associated gene expression in …
  3087. Hypolipidimic Effects of Dried Tomato Pomace Powder on AGING Female Rats
  3088. The fusogen AFF-1 can rejuvenate the regenerative potential of adult dendritic trees by self-fusion
  3089. Myelinodegeneration and Its Influence on Pain: AGING, Diets, and Genetic Dysregulation
  3090. Progressive changes in non-coding RNA profile in leucocytes with age
  3091. Ubiquitin accumulation on disease associated protein aggregates is correlated with nuclear ubiquitin depletion, histone de-ubiquitination and impaired DNA …
  3092. Comparison of cortisol and inflammatory response between aged and middle-aged patients undergoing total hip arthroplasty: a prospective observational …
  3093. Long non-coding RNA: Functional agent for disease traits
  3094. Risk factors for postoperative complications in elderly after colorectal cancer resection
  3095. The effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent
  3096. Hepatostat: Liver regeneration and normal liver tissue maintenance
  3097. Mitochondrial Longevity Pathways
  3098. CONTRIBUTION OF VARIOUS FACTORS IN THE INVERSE RELATIONSHIP OF ALZHEIMER’S DISEASE AND CANCER
  3099. The role of autophagy in AGING: molecular mechanisms
  3100. AAMC. See Association of American Medical Colleges (AAMC) Ablation thermal MR–guided
  3101. Stem Cell Applications in Rejuvenation
  3102. The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic …
  3103. Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
  3104. The relationship between reproductive and biochemical ageing at the time of the menopausal transition
  3105. TORC1 inhibition as an immunotherapy to reduce infections in the elderly
  3106. microRNA in cardiovascular AGING and age-related cardiovascular diseases
  3107. Nervous system ageing
  3108. The ageing brain: effects on DNA repair and DNA methylation in mice
  3109. Nutrition and Healthy AGING
  3110. Evaluating aged mice in three touchscreen tests that differ in visual demands: Impaired cognitive function and impaired visual abilities
  3111. Characterization of epigenetic and transcriptional changes in AGING and Alzheimer’s disease
  3112. Proliferation cycle causes age dependent mitochondrial deficiencies and contributes to the AGING of stem cells
  3113. Growth factor, energy and nutrient sensing signalling pathways in metabolic ageing
  3114. Idiopathic pulmonary fibrosis
  3115. Supply and demand of energy in the oocyte and the role of mitochondria
  3116. Current advances and limitations in modeling ALS/FTD in a dish using induced pluripotent stem cells
  3117. How to get the most bang for your buck: the evolution and physiology of nutrition-dependent resource allocation strategies
  3118. The AGING immune system and nutritional interventions
  3119. Proteostasis and AGING in Saccharomyces cerevisiae-The role of a Peroxiredoxin
  3120. Cellular Senescence and Stem Cell Niche
  3121. Diosmin-induced senescence, apoptosis and autophagy in breast cancer cells of different p53 status and ERK activity
  3122. Membrane Lipid Replacement for chronic illnesses, AGING and cancer using oral glycerolphospholipid formulations with fructooligosaccharides to restore …
  3123. Adequate Protein in Nutrition: Arguments for More or Less?
  3124. Chemical modification of bacterial cellulose for use in regenerative medicine
  3125. AGING and autophagy in hematopoietic stem cells
  3126. Shining the light on senescence associated LncRNAs
  3127. Caloric restriction extends yeast chronological life span by optimizing the Snf1 (AMPK) signaling pathway
  3128. In vivo Mitophagy Monitoring in Caenorhabditis elegans to Determine Mitochondrial Homeostasis
  3129. Life history traits of an extended longevity phenotype of Drosophila melanogaster
  3130. Regulation and Consequences of Retrotransposition During Quiescence in Budding Yeast
  3131. Lack of association between pbmc telomere length and endurance exercise
  3132. Perspective: neuroregenerative nutrition
  3133. Preparation of plasma membrane vesicles from bone marrow mesenchymal stem cells for potential cytoplasm replacement therapy
  3134. Longevity, AGING and DNA damage: investigation of the role of 53BP1 in the maintenance of genomic stability
  3135. Overcoming on-target resistance to tyrosine kinase inhibitors in lung cancer
  3136. Caloric-restriction induced alterations in CG and non-CG methylation attenuate age-associated changes in the old brain
  3137. Polymorphonuclear neutrophil functions are differentially altered in amnestic mild cognitive impairment and mild alzheimer’s disease patients
  3138. Caloric-restriction mitigates age-associated alteration in CG and non-CG methylation in the old brain
  3139. The role of p16INK4a pathway in human epidermal stem cell self-renewal, AGING and cancer
  3140. Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
  3141. The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone …
  3142. Sleep mediates the association between homocysteine and oxidative status in mild cognitive impairment
  3143. Augmenting brain metabolism to increase macro-and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and AGING
  3144. Differing expression of cytokines and tumor markers in combined pulmonary fibrosis and emphysema compared to emphysema and pulmonary fibrosis
  3145. Differential decrease in soluble and DNA-bound telomerase in senescent human fibroblasts
  3146. Exploring a role for regulatory miRNAs in wound healing during ageing: involvement of miR-200c in wound repair
  3147. YuZhenLinusPaulingInstitGeneExpressionLiver. pdf
  3148. Doubling the human lifespan
  3149. Effectiveness of nutritional and exercise interventions to improve body composition and muscle strength or function in sarcopenic obese older adults: A systematic …
  3150. Unraveling the link between the Mdm2-p53 axis and AGING
  3151. Doubling the human lifespan: An interdisciplinary approach to longevity extension
  3152. DNA damage in protective and adverse inflammatory responses: Friend of foe?
  3153. Studies on the delaying effect of caloric restriction on the carcinogenic process.
  3154. Mitochondrial Base Excision Repair
  3155. A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling
  3156. Translational Research in Acute Lung Injury and Pulmonary Fibrosis: Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung …
  3157. Sulforaphane-induced cell cycle arrest and senescence are accompanied by DNA hypomethylation and changes in microRNA profile in breast cancer cells
  3158. Resveratrol attenuates copper-induced senescence by improving cellular proteostasis
  3159. Gender differences in functional disability and self-care among seniors in Bangladesh
  3160. Lamins and metabolism
  3161. The role of the immune system in metabolic health and disease
  3162. Promotive effect of Polygonum multiflorum radix ethanol extract on melanogenesis
  3163. Isolation and prolonged expansion of oral mesenchymal stem cells under clinical-grade, GMP-compliant conditions differentially affects “stemness” properties
  3164. Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis
  3165. Autophagy, its mechanisms and regulation: implications in neurodegenerative diseases
  3166. Assessing Mitochondrial Selective Autophagy in the Nematode Caenorhabditis elegans
  3167. Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin‐1 production
  3168. Circadian Control of Mitochondrial Dynamics and Its Implication in AGING
  3169. Neurodegeneration enhances the development of arthritis
  3170. The use of urinary proteomics in the assessment of suitability of mouse models for ageing
  3171. Inhibitors of DNA methylation support TGF-β1-induced IL11 expression in gingival fibroblasts
  3172. Role of dietary pattern and obesity on telomere homeostasis
  3173. The Role of p16 in Controlling Mammary Epithelial Cell Senescence and Brca1-Deficient Tumorigenesis
  3174. Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers
  3175. Phenomic and Metabolomic Analysis of Chronological AGING in Saccharomyces cerevisiae
  3176. GSK3beta at the intersection of growth, metabolism and longevity
  3177. The co-expression pattern of p63 and HDAC1: a potential way to disclose stem cells in interfollicular epidermis
  3178. Implications of DNA methylation in Parkinson’s disease
  3179. Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B
  3180. Physiological and pathological functions of mitochondrial proteases
  3181. Cytosolic proteostasis through importing of misfolded proteins into mitochondria
  3182. Investigating the Role of Glycogen Accumulation in Neurodegeneration and Brain AGING
  3183. RAP80 binds p32 to preserve the functional integrity of mitochondria
  3184. Prospective Epigenetic Paradigms and Models for Cellular Senescence and Epithelial–Mesenchymal Transition in Organismal Development and AGING
  3185. Is Senescence Important in Hepatic Diseases?
  3186. Parity history determines a systemic inflammatory response to spread of ovarian cancer in naturally aged mice
  3187. Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE−/− mice
  3188. The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical
  3189. Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity
  3190. Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
  3191. Quantitative proteomics analysis of Caenorhabditis elegans upon germ cell loss
  3192. Rescuing Age-related Proteolysis Deficits with Methylene Blue
  3193. Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease
  3194. Autophagy in the vertebrate inner ear
  3195. Doubling healthy lifespan using drug synergy
  3196. Parkinson’s disease: from pathogenesis to pharmacogenomics
  3197. Metabolic effects of fasting on human and mouse blood in vivo
  3198. Mild hypothermia attenuates the anesthetic isoflurane-induced cytotoxicity
  3199. A homeostatic shift facilitates endoplasmic reticulum proteostasis through transcriptional integration of proteostatic stress response pathways
  3200. The Tryptophan Metabolite Kynurenic Acid is a Neuromodulator Mediating Learning, Brain AGING, and Neurodegeneration
  3201. In vitro studies to evaluate the effect of varying culture conditions and IPL fluencies on tenocyte activities
  3202. Molecular Mechanisms Regulating the Interactions of Senescent Cells with the Immune System
  3203. Lung homeostasis: influence of age, microbes, and the immune system
  3204. Mouse models of central nervous system ageing
  3205. Why we age–a new evolutionary view
  3206. Identification of bladder cancer prognostic biomarkers using an ageing gene-related competitive endogenous RNA network
  3207. Longevity Promotion: Multidisciplinary Perspectives
  3208. Doubling healthy lifespan using drug synergy
  3209. The Effect of Age on Social Behaviour In Drosophila Melanogaster and the Progeny of Aged Parents
  3210. PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila
  3211. Nup100 regulates Saccharomyces cerevisiae replicative life span by mediating the nuclear export of specific tRNAs
  3212. Health and Ageing in Older Adults: A gender-specific and life-course perspective
  3213. Development of an LC-MS/MS method for the analysis of Saccharomyces cerevisiae lipidome to determine the mechanism through which plant extract 21 delays …
  3214. Neuromodulation as a cognitive enhancement strategy in healthy older adults: promises and pitfalls
  3215. Brain rules for AGING well: 10 principles for staying vital, happy, and sharp
  3216. Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction
  3217. Circulating levels of soluble Receptor for Advanced Glycation End-products (sRAGE) decrease with AGING and may predict age-related cardiac remodeling
  3218. Treatment of skin AGING and photoAGING with innovative oral dosage forms of nonhydrolized carnosine and carcinine
  3219. Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
  3220. Oleic acid and hydroxytyrosol inhibit cholesterol and fatty acid synthesis in C6 glioma cells
  3221. Caloric restriction promotes structural and metabolic changes in the skin
  3222. AGING and the Plasma Metabolome: Relation to Physiological Function
  3223. Systematic analysis of mitochondrial-auntophagy activity in yeast chronological-life span genetic factors= Análisis sistemático de la autofagia mitocondrial en …
  3224. Studies investigating the distinct effects of estradiol deficiency and AGING on the redox system of skeletal muscle as it relates to strength and power
  3225. Developing Circadian Therapeutics Against Age-Related Metabolic Decline
  3226. ZRF 1 is a novel S6 kinase substrate that drives the senescence programme
  3227. The indirubin derivative 6-bromoindirubin-3′-oxime activates proteostatic modules, reprograms cellular bioenergetic pathways, and exerts antiAGING effects
  3228. Nicotinamide ameliorates disease phenotypes in a human iPSC model of age-related macular degeneration
  3229. Circulating levels of miR-7, miR-152 and miR-192 respond to vitamin D supplementation in adults with prediabetes and correlate with improvements in glycemic …
  3230. Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation
  3231. Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions
  3232. Analysis of phenotype reversibility in Hutchinson-Gilford progeria syndrome in mice
  3233. A circulating microRNA signature predicts age-based development of lymphoma
  3234. Interrelations between mitochondrial DNA copy number and inflammation in older adults
  3235. Species comparison of liver proteomes reveals enhanced lipid metabolism, reduced mitochondrial respiration and enhanced expression of detoxifying …
  3236. Jihad AM Alzyoud, Ilyas M. Khan &
  3237. A novel method to quantify base substitution mutations at the 10− 6 per bp level in DNA samples
  3238. Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice
  3239. Bioactive growth hormone in older men and women: It’s relationship to immune markers and healthspan
  3240. Subtle Changes in Clonal Dynamics Underlie the Age-Related Decline in Neurogenesis
  3241. Charting the dynamic methylome across the human lifespan
  3242. A proteomic atlas of insulin signalling reveals tissue‐specific mechanisms of longevity assurance
  3243. Alterations in Autophagy and Senescence in the Pathologically Aged Uraemic Heart
  3244. Circadian rhythms and proteostasis in AGING
  3245. Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity
  3246. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function
  3247. YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate
  3248. THE ENACTMENT OF ADVANCED STYLE
  3249. Subclinical atherosclerosis, cardiac and kidney function, heart failure, and dementia in the very elderly
  3250. A class of reactive acyl-CoA species reveals the non-enzymatic origins of protein acylation
  3251. Approaches for extending human healthspan: from antioxidants to healthspan pharmacology
  3252. Longitudinal Studies of Caenorhabditis Elegans AGING and Behavior Using a Microfabricated Multi-Well Device
  3253. Boosting ATM Activity Promotes Longevity in Nematodes and Mice
  3254. Regulation and Repair of Neural Stem Cells and the Neurogenic Niche
  3255. Aspirin inhibits LPS-induced macrophage activation via the NF-κB pathway
  3256. Endpoint or kinetic measurement of hydrogen sulfide production capacity in tissue extracts
  3257. The Role of microRNAs in Drosophila Circadian Rhythms and AGING and Genome-wide Identification of Activity-regulated Genes
  3258. Physiological Changes of Senescent Endothelial cells and their Contribution to AGING Phenotype
  3259. Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long‐term intermittent hypoxia
  3260. Protein carbonylation: Principles, analysis, and biological implications
  3261. Substrate selection and its impact on mitochondrial respiration and redox
  3262. Genetic variation in glia–neuron signalling modulates ageing rate
  3263. The histone methyltransferases Set5 and Set1 have overlapping functions in gene silencing and telomere maintenance
  3264. MicroRNA perturbation of the MRN complex buffers DNA damage response from VEGF signaling
  3265. Postmenopausal osteoporosis in rheumatoid arthritis: the estrogen deficiency-immune mechanisms link
  3266. Hormones in clock regulation during ageing
  3267. Extending lifespan through autophagy stimulation: A future perspective
  3268. The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite
  3269. Mutational analysis of fructose-1, 6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress
  3270. Reduced cancer mortality at high altitude: The role of glucose, lipids, iron and physical activity
  3271. HIV/AIDS: oxidative stress and dietary antioxidants
  3272. Human SLE bone marrow mesenchymal stem cells (BMSCs) have a senescence-associated secretory phenotype (SASP) mediated by a MAVS-IFNβ …
  3273. Alterations in Energy Metabolism and Neurodegeneration as a Consequence of DNA Damage
  3274. Similarities and interactions between the ageing process and high chronic intake of added sugars
  3275. Genetic and lifestyle influences on memory, brain structure, and dementia
  3276. The crosstalk between the gut microbiota and mitochondria during exercise
  3277. ANALYSIS OF NEURONAL DIFFERENTIATION IN GENETIC FORMS OF PARKINSON’S DISEASE REVEALS A NEURODEVELOPMENTAL CONTRIBUTION
  3278. Diet-Dependent Balance Between Autophagy and Proliferation Regulates Follicle Stem Cell Lifetime
  3279. Synthetic mRNA devices that detect endogenous proteins and distinguish mammalian cells
  3280. Docking studies and biological evaluation of a potential β-secretase inhibitor of 3-hydroxyhericenone F from Hericium erinaceus
  3281. PARTIAL INHIBITION OF MITOCHONDRIAL COMPLEX I ACTIVATES STRESS RESPONSE PATHWAYS INDUCING A PROTECTION AGAINST OXIDATIVE STRESS
  3282. Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7 …
  3283. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
  3284. Exosomes regulate microglia activation during inflammation and AGING
  3285. Nutrition and Inflammation: are centenarians calorie-restricted like individuals?
  3286. The role of autophagy in AGING-related Osteoarthritis
  3287. The role of autophagy in AGING-related osteoarthritis
  3288. Role of Histone Methyltransferase SET-4 in Developmental Plasticity and Longevity
  3289. REGULATION OF LIFE SPAN BY THE GUT MICROBIOTA IN THE SHORT-LIVED AFRICAN 1 TURQUOISE KILLIFISH 2
  3290. TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells
  3291. Urinary DcR2 is a novel biomarker for tubulointerstitial injury in patients with diabetic nephropathy
  3292. Connexin-dependent intercellular stress signaling in tissue homeostasis and tumor development
  3293. A biochemical assessment of Ochratoxin A stress responses in vitro, with resveratrol as a possible therapeutic intervention.
  3294. LINE-1 repression attenuates degeneration in adult dopaminergic neurons
  3295. The Lucky Years: How to Thrive in the Brave New World of Health
  3296. Validation of Rat Mesentery Culture Model for Time-Lapse Drug Evaluation and Cell Lineage Studies
  3297. Natural genetic variation in C. elegans reveals genomic loci controlling metabolite levels
  3298. Identification of Neuropeptide Y receptors in human articular cartilage: influence of gender and osteoarthritis
  3299. Curriculum Vitae-Pinchas Cohen
  3300. Role of Extracellular Matrix Crosslinking Enzyme Tissue Transglutaminase in Trabecular Meshwork Homeostasis and Regulating Intraocular Pressure
  3301. Alterations in the molecular properties of neural stem cells from aged brains and brain tumors
  3302. The Role of Parkin in Maintaining Proteasome Activity Following Acute Neurotoxic Insult
  3303. Nonparametric Methods for Functional Genomics and Applications to Immune AGING
  3304. Molecular regulation of hair follicle stem and progenitor cell homeostasis
  3305. Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity
  3306. Physical Exercise as an Effective AntiAGING Intervention
  3307. A genetic tool to track protein aggregates and control prion inheritance
  3308. Physical exercise and DNA injury: good or evil?
  3309. Dairy protein, exercise and inflammatory markers in older adults
  3310. Outcome of Emergency Gastrointestinal Procedures in the Elderly
  3311. By Joe C Udeochu
  3312. The Role of Sigma-1 Receptors in an Alzheimer’s Disease Mouse Model
  3313. A non-genetic meiotic repair program inferred from spore survival values in fission yeast wild isolates: a clue for an epigenetic ratchet-like model of ageing?
  3314. Idiopathic Pulmonary Fibrosis
  3315. Overview of autophagy
  3316. Brand positioning in the pharmaceutical industry: content analysis applied to antiAGING drugs
  3317. Physical and functional interactions of the tumor suppressor protein p53 with poly (ADP-ribose) polymerase-1 and its enzymatic product poly (ADP-ribose)
  3318. The Role of Nucleoid Exclusion in the Intracellular Spatial Organization of Escherichia coli
  3319. The relationship between moderate physical activities and sleep quality and quantity among persons with dementia
  3320. 4D analysis of facial ageing using dynamic features
  3321. Inhibition of soluble adenylyl cyclase (SAC) causes a robust increase in glycolysis in cultured astrocytes
  3322. Mechanisms by which nuclear A-type lamins are downregulated in neuroblastoma.
  3323. Optical control of muscarinic acetylcholine receptors using photoswitchable bitopic ligands
  3324. Multimodality ImAGING of Cardiovascular Dysfunction: risk factors, diagnostics and treatment options
  3325. Augmented cerebral mitochondrial function and hippocampal ketone body metabolism in Db/db mice
  3326. Compartmentalised signalling-metabolism coupling in brain cells-putative drug targets for neurological diseases?
  3327. Molecular characterization of the hypoxia-induced mitochondrial activity regulator Ndufa4l2
  3328. MTU01-02
  3329. Macrophages in M1/M2 states and exposed to amyloid-beta: a RNA-seq analysis in human cells
  3330. Biomechanical analyses of ventricular and vascular function in disease models
  3331. Telomerase regulation by non-coding RNAs
  3332. Understanding the Chondrogenic Potential of Articular Chondrocytes
  3333. The Effects of Diet, Body Composition and Exercise on The Serum Metabolome in Health and Disease
  3334. Advancements in forensic DNA-based identification
  3335. Delineating Transcriptional and Epigenetic Regulations in Normal and Ageing Spermatogonial Stem Cells
  3336. DVR-Kongress
  3337. Wnt Signaling Inhibitor Characteristics According to Bone Status, Physical Activity Levels, and Muscle Function in Young and Middle-aged Premenopausal Women
  3338. Abstracts from The 35th Annual National Neurotrauma Symposium July 7–12, 2017 Snowbird, Utah
  3339. The Relationship Between Amount of Physical Activity and Postural Balance in Rural Community Dwelling Adults Age 65 Years and Older
  3340. Darwin: A hardware-acceleration framework for genomic sequence alignment
  3341. Preoperative Evaluation
  3342. Prediction and prevention of suicidality among patients with depressive disorders: comorbidity as a risk factor
  3343. Personalized approach in the treatment of tinnitus and insomnia: combining repetitive transcranial magnetic stimulation and cognitive behavioral therapy
  3344. Evolution of the non-coding genome
  3345. Nephrin-marker for early detection of hypertensive nephropathy
  3346. Degradation of skin elastin in ageing and disease-an ex vivo quantitative proteomic approach
  3347. Predicting cardiovascular risk in diabetic patients: arewe all on the same side?
  3348. Homocysteine: risk factor for coronary artery disease in patients with type 2 diabetes mellitus
  3349. EPMA world congress: traditional forum in predictive, preventive and personalised medicine for multi-professional consideration and consolidation
  3350. PKA phosphorylation of ATAXIN1 in Purkinje cells modulates early onset of ataxia
  3351. A genetic platform for the study of protein perturbation and prion-based inheritance
  3352. The role of selective autophagy on tau clearance
  3353. Mouse models to disentangle the hallmarks of human AGING
  3354. Chronic obstructive pulmonary disease and the hallmarks of AGING
  3355. Hallmarks of cellular senescence
  3356. Hallmarks of brain AGING: adaptive and pathological modification by metabolic states
  3357. Gene expression hallmarks of cellular ageing
  3358. Time and the metrics of AGING
  3359. Therapeutic potential of boosting NAD+ in AGING and age-related diseases
  3360. EVALUATING BIOLOGICAL HALLMARKS OF AGING IN A CLINICAL TRIAL ON AGING: OBSTACLES BETWEEN BENCH AND BEDSIDE
  3361. AGING and the immune system: An overview
  3362. Cellular metabolism and AGING
  3363. On the relationship between AGING & cancer
  3364. AGING epigenetics: changes and challenges
  3365. Effect of resveratrol and pterostilbene on AGING and longevity
  3366. Effects of exercise and AGING on skeletal muscle
  3367. Of microbes and minds: a narrative review on the second brain AGING
  3368. as a model for AGING research
  3369. Sex and AGING
  3370. Translational Medicine of AGING
  3371. Molecular basis and emerging strategies for anti-AGING interventions
  3372. AGING hallmarks: the benefits of physical exercise
  3373. Keynote lecture: strategies for optimal cardiovascular AGING
  3374. Genomic instabilities, cellular senescence, and AGING: in vitro, in vivo and AGING-like human syndromes
  3375. Resveratrol and/or exercise training counteract AGING-associated decline of physical endurance in aged mice; targeting mitochondrial biogenesis and function
  3376. AGING, inflammation and the environment
  3377. Metabolic control of AGING in C. elegans
  3378. Potential mechanisms of age acceleration caused by estrogen deprivation: do endocrine therapies carry the same risks?
  3379. Lung cellular senescence is independent of AGING in a mouse model of COPD/emphysema
  3380. Biomedical Research in AGING
  3381. EVIDENCE THAT EPIGENETIC ALTERATIONS DRIVE MAMMALIAN AGING
  3382. Population Epigenomics and AGING
  3383. Circulating mitochondrial DNA at the crossroads of mitochondrial dysfunction and inflammation during AGING and muscle wasting disorders
  3384. The spectrum of fundamental basic science discoveries contributing to organismal AGING
  3385. Modifying progression of AGING and reducing the risk of neurodegenerative diseases by probiotics and synbiotics
  3386. Pathways of cellular proteostasis in AGING and disease
  3387. Oral health in geroscience: animal models and the AGING oral cavity
  3388. Geroscience
  3389. AGING in the cardiovascular system: lessons from Hutchinson-Gilford progeria syndrome
  3390. The tame trial: a prototype for geroscience-guided therapeutics
  3391. Senolytic drugs in respiratory medicine: is it an appropriate therapeutic approach?
  3392. Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90+ study
  3393. Novel anti-AGING gene NM_026333 contributes to proton-induced AGING via NCX1-pathway
  3394. Targeting AGING for disease modification in osteoarthritis
  3395. Sarcopenia and AGING
  3396. Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype
  3397. Inhibition of mTOR Signalling: A Potential Anti-AGING Drug Strategy
  3398. Introduction to Cardiovascular AGING Compendium: “AGING as the Quintessential Complex Phenotype”
  3399. Targeting senescence to delay progression of multiple sclerosis
  3400. Therapeutic manipulation of cancer cell metabolism with the mitochondrial metabolism inhibitor Cpi-613 in addition to chemotherapy abrogates the adverse …
  3401. At the crossroads between neurodegeneration and cancer: a review of overlapping biology and its implications
  3402. Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint …
  3403. New phytochemicals as potential human anti-AGING compounds: Reality, promise, and challenges
  3404. mTOR as regulator of lifespan, AGING, and cellular senescence: a mini-review
  3405. The dysfunctional MDM2–p53 axis in adipocytes contributes to AGING-related metabolic complications by induction of lipodystrophy
  3406. AGING and proteins: what does proteostasis have to do with age?
  3407. Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans
  3408. Horizons in the evolution of AGING
  3409. Fibrosis: lessons from OMICS analyses of the human lung
  3410. A review on anti-AGING properties of probiotics
  3411. Senescence and AGING: Causes, consequences, and therapeutic avenues
  3412. The Basics of Biogerontology
  3413. Mechanisms and consequences of oxidative stress in lung disease: therapeutic implications for an AGING populace
  3414. The paths of mortality: how understanding the biology of AGING can help explain systems behavior of single cells
  3415. A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup
  3416. An international perspective on chronic multimorbidity: approaching the elephant in the room
  3417. A distinct pattern of circulating amino acids characterizes older persons with physical frailty and sarcopenia: results from the BIOSPHERE study
  3418. Elixir of life: thwarting AGING with regenerative reprogramming
  3419. A call to action in hematologic disorders: A report from the ASH scientific workshop on hematology and AGING
  3420. A network-based meta-analysis for characterizing the genetic landscape of human AGING
  3421. Development of clinical trials to extend healthy lifespan
  3422. Angiogenesis: focusing on the effects of exercise in AGING and cancer
  3423. Lithium treatment and mechanisms of AGING
  3424. The geometric framework: An approach for studying the impact of nutrition on healthy AGING
  3425. Insulin signaling regulates oocyte quality maintenance with age via cathepsin B activity
  3426. Cross-organelle communication at the core of longevity
  3427. AGING across the tree of life: The importance of a comparative perspective for the use of animal models in AGING
  3428. Histone modification changes during AGING: cause or consequence?—What we have learned about epigenetic regulation of AGING from model organisms
  3429. A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of AGING yeast
  3430. The yeast replicative AGING model
  3431. Ayurveda and the science of AGING
  3432. A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence
  3433. G protein-coupled receptor systems as crucial regulators of DNA damage response processes
  3434. Unveiling epigenetic regulation in cancer, AGING, and rejuvenation with in vivo reprogramming technology
  3435. AGING With HIV and Oxidative Stress
  3436. Towards a biological geriatric assessment
  3437. Relevance of the p53–MDM2 axis to AGING
  3438. Molecular and cellular mechanisms of AGING and age-related disorders
  3439. Histone modifications in AGING: the underlying mechanisms and implications
  3440. Role of endogenous glucocorticoids in cancer in the elderly
  3441. Connecting chaperone-mediated autophagy dysfunction to cellular senescence
  3442. Enhanced expression of thioredoxin‐interacting‐protein regulates oxidative DNA damage and AGING
  3443. Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells
  3444. The impact of AGING on mechanisms of mammalian epimorphic regeneration
  3445. The mitochondria in lung fibrosis: friend or foe?
  3446. The African turquoise killifish Nothobranchius furzeri as a model for AGING research
  3447. New mechanisms driving muscle stem cell regenerative decline with AGING
  3448. AGING, inflammation and cancer
  3449. Modulation of mitochondrial bioenergetics as a therapeutic strategy in Alzheimer’s disease
  3450. Immunosenescence and lymphomagenesis
  3451. Age reprogramming and epigenetic rejuvenation
  3452. Neuropathology and cognitive performance in self-reported cognitively healthy centenarians
  3453. AGING related changes in circulating reactive oxygen species (ROS) and protein carbonyls are indicative of liver oxidative injury
  3454. Caloric restriction research: new perspectives on the biology of AGING
  3455. Hacking AGING: a strategy to use big data from medical studies to extend human life
  3456. Pioglitazone attenuates AGING-related disorders in aged apolipoprotein E deficient mice
  3457. Animal Models of Pathological AGING
  3458. Nucleolar function in lifespan regulation
  3459. Age is relative—Impact of donor age on induced pluripotent stem cell-derived cell functionality
  3460. Transcriptome network analysis reveals AGING-related mitochondrial and proteasomal dysfunction and immune activation in human thyroid
  3461. The nematode Caenorhabditis elegans as a model for AGING research
  3462. Epigenetic regulation of skin cells in natural AGING and premature AGING diseases
  3463. Longevity Escape Velocity Medicine: A New Medical Specialty for Longevity?
  3464. The integration of inflammAGING in age-related diseases
  3465. Opportunities for organoids as new models of AGING
  3466. AGING in a relativistic biological space-time
  3467. Fifteen years of progress in understanding frailty and health in AGING
  3468. Caloric restriction and cellular senescence
  3469. Can an infection hypothesis explain the beta amyloid hypothesis of Alzheimer’s disease?
  3470. Molecular mechanisms regulating lifespan and environmental stress responses
  3471. Glycomic and proteomic changes in AGING brain nigrostriatal pathway
  3472. Caenorhabditis elegans as a model organism for AGING: relevance, limitations and future
  3473. Effects of resveratrol and other polyphenols on Sirt1: relevance to brain function during AGING
  3474. Towards success against senescence?
  3475. Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, provoke propagated neuronal death
  3476. Biological processes modulating longevity across primates: a phylogenetic genome-phenome analysis
  3477. The quest for osteoporosis mechanisms and rational therapies: how far we’ve come, how much further we need to go
  3478. Theories and mechanisms of AGING
  3479. Environmental enrichment improves cognitive deficits, AD hallmarks and epigenetic alterations presented in 5xFAD mouse model
  3480. Senescence of bone marrow-derived mesenchymal stem cells from patients with idiopathic pulmonary fibrosis
  3481. Recent insights into the cellular and molecular determinants of AGING
  3482. Sex differences in AGING: genomic instability
  3483. Euchromatic histone methyltransferases regulate peripheral heterochromatin tethering via histone and non-histone protein methylations
  3484. When nature’s robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human AGING disease pathologies
  3485. DICER1: A key player in rheumatoid arthritis, at the crossroads of cellular stress, innate immunity, and chronic inflammation in AGING
  3486. Forward and reverse genetics approaches to uncover metabolic AGING pathways in Caenorhabditis elegans
  3487. AGING of hematopoietic stem cells
  3488. Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update
  3489. A distinct pattern of circulating amino acids characterizes older persons with physical frailty and Sarcopenia: Preliminary results from the BIOSPHERE Study
  3490. Machine learning on human muscle transcriptomic data for biomarker discovery and tissue-specific drug target identification
  3491. Fuchs endothelial corneal dystrophy through the prism of oxidative stress
  3492. VU Research Portal
  3493. Brain AGING: Hsp90 and neurodegenerative diseases
  3494. Higher gene expression stability during AGING in long-lived giant mole-rats than in short-lived rats
  3495. Biological Determinants of Men’s Health and AGING
  3496. The role of mitochondrial ROS in the AGING brain
  3497. Telomere homeostasis: interplay with magnesium
  3498. Human Muscle Stem Cells and the Effect of AGING
  3499. Immune-inflammatory responses in the elderly: an update
  3500. Mitochondrial quality control mechanisms as molecular targets in cardiac ageing
  3501. Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease
  3502. Mitochondria, its DNA and telomeres in ageing and human population
  3503. A futile battle? Protein quality control and the stress of AGING
  3504. Invertebrates as model organisms for research on AGING biology
  3505. Facing up to the global challenges of ageing
  3506. Walnut consumption for two years and leukocyte telomere attrition in Mediterranean elders: results of a randomized controlled trial
  3507. Barshop Symposium on AGING 2017 Abstracts
  3508. Olive oil and skin anti-AGING.
  3509. The Effect of AGING-Like Stressors on AGING Related Candidate Genes in Mice
  3510. Computational approaches for the systematic analysis of AGING-associated molecular alterations
  3511. Autophagy and proteostasis in the control of synapse AGING and disease
  3512. The reality of getting old
  3513. Hydra, a model system for deciphering the mechanisms of AGING and resistance to AGING
  3514. Recent advances in the systems biology of AGING
  3515. Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults
  3516. Heart-breaking telomeres
  3517. Intracellular and intercellular signalling mechanisms following DNA damage are modulated by PINK1
  3518. The guardian of the genome revisited: p53 downregulates genes required for telomere maintenance, DNA repair, and centromere structure
  3519. Lineage plasticity in cancer progression and treatment
  3520. Restoring effects of natural anti-oxidant quercetin on cellular senescent human dermal fibroblasts
  3521. AGING and drug discovery
  3522. Intestinal snakeskin limits microbial dysbiosis during AGING and promotes longevity
  3523. Asthma in the elderly and late‐onset adult asthma
  3524. PIWI-piRNA pathway: Setting the pace of AGING by reducing DNA damage
  3525. Understanding epigenetics in the neurodegeneration of Alzheimer’s disease: SAMP8 mouse model
  3526. Human neurons to model AGING: a dish best served old
  3527. Epigenetic erosion in adult stem cells: drivers and passengers of AGING
  3528. An analysis of AGING-related genes derived from the genotype-tissue expression project (GTEx)
  3529. Oxidative stress and AGING: learning from yeast lessons
  3530. Stem cells and anti-AGING genes: double-edged sword—do the same job of life extension
  3531. AGING and neurodegeneration are associated with increased mutations in single human neurons
  3532. miRACA: A database for miRNAs associated with cancers and age related disorders (ARD)
  3533. Physical activity: Evidence for the Anti-ageing effects in elderly
  3534. Accelerated AGING in schizophrenia and related disorders: Future research
  3535. Age-and sex-dependent changes in levels of circulating brain-enriched microRNAs during normal AGING
  3536. Telomeres, nutrition, and longevity: can we really navigate our AGING?
  3537. Novel role of the SIRT4-OPA1 axis in mitochondrial quality control
  3538. Pharmaceutical intervention of AGING
  3539. Protease Silencing to Explore the Molecular Mechanisms of Cancer and AGING
  3540. The role of Na/K-ATPase signaling in oxidative stress related to AGING: implications in obesity and cardiovascular disease
  3541. A decay of the adaptive capacity of the unfolded protein response exacerbates Alzheimer’s disease
  3542. AGING: Antagonistic pleiotropy supported by gut eating
  3543. non-coding RNAs: entwining metabolism and AGING
  3544. Autophagy in cardiovascular AGING
  3545. Sirtuins and accelerated AGING in scleroderma
  3546. The synergy of AGING and LPS exposure in a mouse model of Parkinson’s disease
  3547. Some metabolites act as second messengers in yeast chronological AGING
  3548. CDK4, a new metabolic sensor that antagonizes AMPK
  3549. A polymorphism in the tumor suppressor p53 affects AGING and longevity in mouse models
  3550. Healthy AGING and Epigenetic Drugs for Diabetes and Obesity: A Novel Perspective
  3551. Somatic mutations in neurons during AGING and neurodegeneration
  3552. Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of AGING in …
  3553. Physical activity and nutrition: two promising strategies for telomere maintenance?
  3554. Effects of acute and chronic exercise on immunological parameters in the elderly aged: can physical activity counteract the effects of AGING?
  3555. General Introduction AGING of Hematopoietic Stem cells
  3556. Epigenetics and AGING research: Between adult malleability and early life programming
  3557. Hsp90 inhibitors as senolytic drugs to extend healthy AGING
  3558. Age-related dataset on the mechanical properties and collagen fibril structure of tendons from a murine model
  3559. Neuropathology and cognitive performance in centenarians
  3560. Biomarkers of cellular senescence and skin AGING
  3561. Single-cell chromatin modification profiling reveals increased epigenetic variations with AGING
  3562. In vivo X-nuclear MRS imAGING methods for quantitative assessment of neuroenergetic biomarkers in studying brain function and AGING
  3563. Tetrahydroxystilbene glucoside delayed senile symptoms in old mice via regulation of the AMPK/SIRT1/PGC-1α signaling cascade
  3564. Epigenetic regulation of cell fate reprogramming in AGING and disease: A predictive computational model
  3565. Impact of age on disease progression and microenvironment in oral cancer
  3566. The role of advanced glycation end products in AGING and metabolic diseases: bridging association and causality
  3567. Behead and live long or the tale of cathepsin L
  3568. Myotonic Dystrophy—A Progeroid Disease?
  3569. Novel targets for delaying AGING: the importance of the liver and advances in drug delivery
  3570. Identifying ubiquitinated proteins and aggregates
  3571. DISCOVERY OF A NOVEL CIRCULATING PEPTIDOME IN HUMAN SERUM THAT CORRELATES WITH AGING
  3572. Methionine restriction extends lifespan in progeroid mice and alters lipid and bile acid metabolism
  3573. The epigenetic regulation of telomere maintenance in AGING
  3574. Designing drug trials for frailty: ICFSR Task Force 2018
  3575. With great age comes great metastatic ability: ovarian cancer and the appeal of the AGING peritoneal microenvironment
  3576. Eleven telomere, epigenetic clock, and biomarker-composite quantifications of biological AGING: do they measure the same thing?
  3577. Higher transcriptome stability during AGING in long-lived giant mole-rats compared to short-lived rats
  3578. Apelin/APJ system: A novel promising target for anti-AGING intervention
  3579. A cell-intrinsic interferon-like response links replication stress to cellular AGING caused by progerin
  3580. AMP-activated protein kinase regulation of the NLRP3 inflammasome during AGING
  3581. Spermidine in health and disease
  3582. ATF6 safeguards organelle homeostasis and cellular AGING in human mesenchymal stem cells
  3583. A time to fast
  3584. Human AGING and disease: lessons from age-related macular degeneration
  3585. Nasal delivery of nerve growth factor rescue hypogonadism by up-regulating GnRH and testosterone in AGING male mice
  3586. Single-cell transcriptomics of the aged mouse brain reveals convergent, divergent and unique AGING signatures
  3587. Glucocorticoid‐mediated modulation of morphological changes associated with AGING in microglia
  3588. Premature physiologic AGING as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer
  3589. Gut microbiome and AGING: Physiological and mechanistic insights
  3590. AGING kidney and AGING-related disease
  3591. The RNA world of human ageing
  3592. Lung tissue gene-expression signature for the ageing lung in COPD
  3593. Targeting the BECN1-BCL2 autophagy regulatory complex to promote longevity
  3594. 11β-HSD1 inhibition by RL-118 promotes autophagy and correlates with reduced oxidative stress and inflammation, enhancing cognitive performance in SAMP8 …
  3595. Mechanisms and Treatment of Blood-brain Barrier Dysfunction and Related Pathology During AGING
  3596. Next-generation sequencing and quantitative proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in …
  3597. Telomere length as a biomarker of accelerated AGING: is it influenced by dietary intake?
  3598. Resveratrol and SIRT1 activators for the treatment of AGING and age-related diseases
  3599. Cardiovascular AGING: the unveiled enigma from bench to bedside
  3600. Eric B. Emmons, Youngcho Kim, and
  3601. Adrenergic nerve degeneration in bone marrow drives AGING of the hematopoietic stem cell niche
  3602. Response to Le Bourg
  3603. Comparative metabolomics of AGING in a long-lived bat: insights into the physiology of extreme longevity
  3604. Retrospective Three-dimensional facial soft tissue analysis in skeletal Class I malocclusions with premolar extractions
  3605. Effect of polysaccharides from a Korean ginseng berry on the immunosenescence of aged mice
  3606. Possible role of ginsenoside Rb1 in skin wound healing via regulating senescent skin dermal fibroblast
  3607. Glycogen regulates cellular proliferation in the context of AGING, tumorigenesis, and hepatic regeneration
  3608. Fat and bone: PGC-1α regulates mesenchymal cell fate during AGING and osteoporosis
  3609. The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature AGING
  3610. The relationship between dietary macronutrients and hepatic telomere length in AGING mice
  3611. Evaluation of oxidative stress in cardiomyocytes during the AGING process in rats treated with resveratrol
  3612. Role of Forkhead Box O (FOXO) transcription factor in AGING and diseases
  3613. The molecular intersection between senescence and major depression in the elderly
  3614. Comparative study of serum lipid profiles in nepalese cancer patients attending a tertiary care hospital
  3615. Toward Using Fluorescent Nanodiamonds To Study Chronological AGING in Saccharomyces cerevisiae
  3616. Gene expression signature of the ageing lung: breathing new life into COPD
  3617. AGING of the bone
  3618. Modulation of the process of AGING in human organism: recent advances in biomarkers for diagnosis and treatment
  3619. Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis
  3620. Abnormal epigenetic regulation of immune system during AGING
  3621. Influence of cell distribution and diabetes status on the association between mitochondrial DNA copy number and AGING phenotypes in the In CHIANTI study
  3622. A new AGING measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: a cohort study
  3623. Immunosenescence of natural killer cells, inflammation, and Alzheimer’s disease
  3624. An overview of treatment strategies for Hutchinson-Gilford Progeria syndrome
  3625. Bone marrow neutrophil AGING in sickle cell disease mice is associated with impaired osteoblast functions
  3626. Drosophila as a model for ageing
  3627. Elastin molecular AGING promotes MDA‐MB‐231 breast cancer cell invasiveness
  3628. Nutrition and ageing
  3629. Oxidative stress in mesenchymal stem cell senescence: regulation by coding and noncoding RNAs
  3630. Resilience to AGING in the regeneration‐capable flatworm Macrostomum lignano
  3631. Three-year changes in physical activity and subsequent loss of ability to walk 400-m in older adults: The InCHIANTI study
  3632. Homeostatic interplay between FoxO proteins and ER proteostasis in cancer and other diseases
  3633. The AGING mitochondria
  3634. AGING and chromatoid body assembly: Are these two physiological events linked?
  3635. Analysis of DNA modifications in AGING research
  3636. Periodontology for Geriatric Patients
  3637. A call for a neuroscience approach to cancer-related cognitive impairment
  3638. Keeping it tight: The relationship between bacterial dysbiosis, septate junctions, and the intestinal barrier in Drosophila
  3639. AGING-related increase in store-operated Ca2+ influx in human ventricular fibroblasts
  3640. DNA damage and oxidative stress in long-lived aquatic organisms
  3641. Emerging role of extracellular vesicles as a senescence-associated secretory phenotype: Insights into the pathophysiology of lung diseases
  3642. Signaling pathways regulating hematopoietic stem cell and progenitor AGING
  3643. Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation
  3644. Beyond ROS clearance: Peroxiredoxins in stress signaling and AGING
  3645. Blank spots on the map: some current questions on nuclear organization and genome architecture
  3646. Comparing the effects of low-protein and high-carbohydrate diets and caloric restriction on brain AGING in mice
  3647. MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction
  3648. The role of pulmonary and systemic immunosenescence in acute lung injury
  3649. Comprehensive geriatric assessment: an updated perspective
  3650. Urinary 8-hydroxydeoxyguanosine is a better biomarker of AGING in non-smokers
  3651. Muscle stem cells and AGING
  3652. Mitochondrial and reactive oxygen species signaling coordinate stem cell fate decisions and life long maintenance
  3653. Immune senescence, epigenetics and autoimmunity
  3654. DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936
  3655. Chronic Obstructive Pulmonary Disease (COPD) as a disease of early AGING: Evidence from the EpiChron Cohort
  3656. Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated AGING
  3657. The fountain of youth: it’s all in our veins
  3658. Update on mitochondria and muscle AGING: all wrong roads lead to sarcopenia
  3659. Long-term effects of dietary protein and branched-chain amino acids on metabolism and inflammation in mice
  3660. ER proteostasis control of neuronal physiology and synaptic function
  3661. Inorganic nitrate alleviates the senescence-related decline inliver function
  3662. BUBR1 insufficiency is correlated with eNOS reduction experimentally in vitro and in vivo, and in gastric cancer tissue
  3663. SNCA overexpression disturbs hippocampal gene expression trajectories in midlife
  3664. Back to the future: epigenetic clock plasticity towards healthy AGING
  3665. Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production
  3666. Endothelial cell metabolism in atherosclerosis
  3667. AGING affects the in vivo regenerative potential of human mesoangioblasts
  3668. Loss of ovarian hormones and accelerated somatic and mental AGING
  3669. IGFBP-3 plays an important role in senescence as an AGING marker
  3670. Fighting the Cause of Alzheimer’s and GNE Myopathy
  3671. Emerging omics approaches in AGING research
  3672. Targeting mitochondria to counteract age-related cellular dysfunction
  3673. Immune cells and inflammation in AKI to CKD progression
  3674. Autophagy induction: A promising antiAGING strategy
  3675. The effect of different levels of dietary restriction on glucose homeostasis and metabolic memory
  3676. Chromatin architectural changes during cellular senescence and AGING
  3677. Oxidative stress and the epigenetics of cell senescence: Insights from progeroid syndromes
  3678. Experimental models of human skin AGING
  3679. Trillium tschonoskii maxim saponin mitigates D-galactose-induced brain AGING of rats through rescuing dysfunctional autophagy mediated by Rheb-mTOR …
  3680. Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue
  3681. Cellular reprogramming: A new way to understand AGING mechanisms
  3682. Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
  3683. To Find and Destroy: Identification and Elimination of Senescent Cells
  3684. The temporal sequence of improved mitochondrial function on the dynamics of respiration, mobility, and cognition in aged Drosophila
  3685. Effects of resveratrol on the renin-angiotensin system in the AGING kidney
  3686. Exosomes as mediators of the systemic adaptations to endurance exercise
  3687. Regeneration of injured tissue: stem cell dynamics at interplay with mTORC1
  3688. Repression of human and mouse brain inflammAGING transcriptome by broad gene-body histone hyperacetylation
  3689. Role of Autophagy in AGING of Hematopoietic Stem Cells and Their Niche: Relevance in Clinical Transplantations and Regenerative Medicine
  3690. Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice
  3691. Extracellular vesicles, ageing, and therapeutic interventions
  3692. Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway
  3693. Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of …
  3694. Epigenetic biomarkers for biological age
  3695. Chronic exposure to triadimenol at environmentally relevant concentration adversely affects AGING biomarkers in Caenorhabditis elegans associated with insulin/IGF-1 …
  3696. Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in AGING C57BL/6J mice
  3697. Aerobic exercise‑stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney
  3698. The impact of the microbiome on immunosenescence
  3699. Longevity, metabolic disease, and community health
  3700. Macrophages in the AGING liver and age-related liver disease
  3701. Metformin directly targets the H3K27me3 demethylase KDM6A/UTX
  3702. Role of the inflammation-autophagy-senescence integrative network in osteoarthritis
  3703. Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function
  3704. p53 isoforms regulate premature AGING in human cells
  3705. Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence
  3706. Role of sphingolipids in senescence: implication in AGING and age-related diseases
  3707. Change in the rate of biological AGING in response to caloric restriction: CALERIE Biobank analysis
  3708. Deep sequencing of the mitochondrial genome reveals common heteroplasmic sites in NADH dehydrogenase genes
  3709. Stem cells in dermatology and anti-AGING care of the skin
  3710. Sex-specific associations between telomere length and candidate miRNA expression in placenta
  3711. Royal jelly delays motor functional impairment during AGING in genetically heterogeneous male mice
  3712. Cover Page Article Discoveries
  3713. Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease
  3714. Mitochondrial Paths to Sarcopenia–A Refined Short Review
  3715. EVALUATION OF THE EFFECTS OF FTO AND ENVIRONMENT ON BODY MASS INDEX (BMI) IN A MULTI-ETHNIC COHORT OF OLDER ADULTS
  3716. Association Between Androgen Deprivation Therapy for Prostate Cancer and Alzheimer’s Disease
  3717. Metformin in Idiopathic Pulmonary Fibrosis” Seeking the Holy-Grail through Drug-Repositioning”
  3718. Elevated serum IL-6 and adiponectin levels are associated with frailty and physical function in Chinese older adults
  3719. Blood Telomere Length changes after DRV/R+ either RAL or TDF/FTC as first line ART
  3720. AGING in the brain: new roles of epigenetics in cognitive decline
  3721. Enhancing lysosomal activation restores neural stem cell function during AGING
  3722. Positive cytoplasmic UCHL5 tumor expression in gastric cancer is linked to improved prognosis
  3723. Cellular metabolism and oxidative stress as a possible determinant for longevity in small breed and large breed dogs
  3724. Identification of key pathways and metabolic fingerprints of longevity in C. elegans
  3725. AGING and AGING-associated diseases: a microRNA-based endocrine regulation hypothesis
  3726. Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation
  3727. Mechanisms of vascular AGING
  3728. Age differences in age perceptions and developmental transitions
  3729. Caloric restriction study design limitations in rodent and nonhuman primate studies
  3730. Chaperone-Mediated Autophagy
  3731. Role of Prion protein in premature senescence of human fibroblasts
  3732. The Na/K-ATPase oxidant amplification loop regulates AGING
  3733. Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature AGING
  3734. Modeling AGING and Age-Associated Pathology in Zebrafish
  3735. Chromatin changes trigger laminin genes dysregulation in AGING kidneys
  3736. Activating the anaphase promoting complex to enhance genomic stability and prolong lifespan
  3737. Glutaredoxin-1 silencing induces cell senescence via p53/p21/p16 signaling axis
  3738. Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases
  3739. Alu siRNA to increase Alu element methylation and prevent DNA damage
  3740. Rank-related contrasts in longevity arise from extra-group excursions not delayed senescence in a cooperative mammal
  3741. Vascular senescence in cardiovascular and metabolic diseases
  3742. Glutathione as a marker for human disease
  3743. Exercise Medicine
  3744. The Place of Geroprotective Agents in Life Quality and Longevity of Companion Animals
  3745. AGING and the Brain
  3746. Recombinant buckwheat glutaredoxin intake increases lifespan and stress resistance via hsf-1 upregulation in Caenorhabditis elegans
  3747. Testing a model of successful AGING in a cohort of masters swimmers
  3748. Nrf2: Molecular and epigenetic regulation during AGING
  3749. Idiopathic pulmonary fibrosis: AGING, mitochondrial dysfunction, and cellular bioenergetics
  3750. Blood Markers in Healthy-Aged Nonagenarians: A Combination of High Telomere Length and Low Amyloidβ Are Strongly Associated With Healthy AGING in …
  3751. Emerging roles for sphingolipids in cellular AGING
  3752. The Miniature-chemostat AGING Device: A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of replicatively AGING …
  3753. Molecular mechanisms and cellular pathways implicated in Machado-Joseph disease pathogenesis
  3754. Absolute quantitative lipidomics reveals lipidome-wide alterations in AGING brain
  3755. Substrate topography modulates cell AGING on a progeria cell model
  3756. All about the core: a therapeutic strategy to prevent protein accumulation with proteasome core particle stimulators
  3757. DEVELOPMENT OF A NOVEL METABOLIC GLYCO-SENSING APPROACH WITH ANTI-AGING POTENTIAL
  3758. Osteogenesis and AGING: lessons from mesenchymal stem cells
  3759. Whole-transcriptome changes in gene expression accompany AGING of sensory neurons in Aplysia californica
  3760. Zebrafish AGING models and possible interventions
  3761. Translational geroscience: From invertebrate models to companion animal and human interventions
  3762. Isogenic organisms age at different rates due to critical-slowing-down of damage removal
  3763. Early senescence and leukocyte telomere shortening in schizophrenia: a role for cytomegalovirus infection?
  3764. Human ageing genomic resources: new and updated databases
  3765. Increased epigenetic age in normal breast tissue from luminal breast cancer patients
  3766. Fisetin as a caloric restriction mimetic protects rat brain against AGING induced oxidative stress, apoptosis and neurodegeneration
  3767. Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence
  3768. AGING of complex systems
  3769. Human AGING and cancer: role of miRNA in tumor microenvironment
  3770. Fasting activates fatty acid oxidation to enhance intestinal stem cell function during homeostasis and AGING
  3771. Epigenetic age in male combat-exposed war veterans: associations with posttraumatic stress disorder status
  3772. The Lysosome, Elixir of Neural Stem Cell Youth
  3773. Impaired immune surveillance accelerates accumulation of senescent cells and AGING
  3774. 3′ UTR lengthening as a novel mechanism in regulating cellular senescence
  3775. AGING-induced biological changes and cardiovascular diseases
  3776. Major trauma and acceleration of the ageing process
  3777. The role of autophagy in the regulation of yeast life span
  3778. The mitochondrial contribution to animal performance, adaptation, and life-history variation
  3779. Proteasomal function is impaired in human osteoarthritic chondrocytes and promotes decreased SOX9 and aggrecan levels
  3780. Effects of Novel AGING-Delaying Plant Extracts on the Lipid Composition of the Yeast Saccharomyces Cerevisiae
  3781. Cross-species comparison of proteome turnover kinetics
  3782. The ageing brain in sleep apnoea: paradoxical resilience, survival of the fittest, or simply comparing apples and oranges?
  3783. Somatic mutant clones colonize the human esophagus with age
  3784. Cellular senescence: a view throughout organismal life
  3785. What do experimental models teach us about comorbidities in stroke?
  3786. TORC1 inhibition enhances immune function and reduces infections in the elderly
  3787. Implementation of environmental enrichment after middle age promotes healthy AGING
  3788. Effects of Acarbose on Age-Related Declines in Motor and Cardiac Function
  3789. An overview of the role of lipofuscin in age-related neurodegeneration
  3790. Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX 9 and Aggrecan
  3791. AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer
  3792. Role of dietary fat and supplementation in modulating neurodegenerative pathology in two animal model systems
  3793. Oxysterol signatures distinguish age-related macular degeneration from physiologic AGING
  3794. Is there a link between AGING and microbiome diversity in exceptional mammalian longevity?
  3795. Kynurenic acid accumulation underlies learning and memory impairment associated with AGING
  3796. Polyamine catabolism and oxidative damage
  3797. Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) …
  3798. Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort
  3799. Age structure landscapes emerge from the equilibrium between AGING and rejuvenation in bacterial populations
  3800. Articular cartilage AGING-potential regenerative capacities of cell manipulation and stem cell therapy
  3801. Targeting of NAT10 enhances healthspan in a mouse model of human accelerated AGING syndrome
  3802. Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly
  3803. Evolution favours AGING in populations with assortative mating and in sexually dimorphic populations
  3804. Lactobacillus paracasei PS23 delays progression of age-related cognitive decline in senescence accelerated mouse prone 8 (SAMP8) mice
  3805. Tissue engineering and regenerative medicine: a translational research for antiAGING strategy
  3806. The causal relationship between epigenetic abnormality and cancer development: in vivo reprogramming and its future application
  3807. Implementing a method for studying longitudinal DNA methylation variability in association with age
  3808. Dwarf mice and AGING
  3809. Regulation of reproduction and longevity by nutrient-sensing pathways
  3810. Growth Hormones and AGING 26
  3811. Ghrelin signaling in immunometabolism and inflamm-AGING
  3812. Senescent cells and osteoarthritis: a painful connection
  3813. Sex-dependent differences in liver and gut metabolomic profiles with acarbose and calorie restriction in C57BL/6 mice
  3814. Long-lived rodents reveal signatures of positive selection in genes associated with lifespan
  3815. Machine learning based classification of cells into chronological stages using single-cell transcriptomics
  3816. Anti-senescence compounds: a potential nutraceutical approach to healthy AGING
  3817. Impaired DNA demethylation of C/EBP sites causes premature AGING
  3818. The interplay between immunity and AGING in Drosophila
  3819. Sex and the AGING Immune System
  3820. Resistance training prevents muscle loss induced by caloric restriction in obese elderly individuals: a systematic review and meta-analysis
  3821. The association between obstructive sleep apnea and shortened telomere length: a systematic review and meta-analysis
  3822. Epigenetic influences on AGING: a longitudinal genome-wide methylation study in old Swedish twins
  3823. Cancer chemoprevention via activation of proteostatic modules
  3824. ALDH2 activity reduces mitochondrial oxygen reserve capacity in endothelial cells and induces senescence properties
  3825. Inflammation and Trajectory of Renal Function in Community‐Dwelling Older Adults
  3826. Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer’s disease
  3827. AGING Process Immunity and Its Relation with Periodontal Disease in Genetic Aspect
  3828. Sexual activity affects the redox profile along the AGING process in male rats
  3829. Stem cell transcription factor FoxO controls microbiome resilience in Hydra
  3830. Diet quality and telomere length in older Australian men and women
  3831. Microenvironment-cell nucleus relationship in the context of oxidative stress
  3832. Epigenetic mechanisms impacting AGING: a focus on histone levels and telomeres
  3833. Brain age predicts mortality
  3834. Whey protein concentrate wpc-80 improves antioxidant defense systems in the salivary glands of 14-month wistar rats
  3835. Mitochondria-associated membranes in AGING and senescence: structure, function, and dynamics
  3836. TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure
  3837. Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila …
  3838. Decelerated DNA methylation age predicts poor prognosis of breast cancer
  3839. Metformin alleviates human cellular AGING by upregulating the endoplasmic reticulum glutathione peroxidase 7
  3840. The systems biology of single-cell AGING
  3841. Leukocyte telomere length and chronic conditions in older women of northeast brazil: a cross-sectional study
  3842. Epigenetic modifications in cardiovascular AGING and diseases
  3843. DNA methyltransferases, DNA methylation, and age-associated cognitive function
  3844. Nutriepigenetics and cardiovascular disease
  3845. Long non-coding RNAs in neuronal AGING
  3846. Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics
  3847. Epigenetic effects of metformin: from molecular mechanisms to clinical implications
  3848. Vive la radioresistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and …
  3849. Understanding lamin proteins and their roles in AGING and cardiovascular diseases
  3850. The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma
  3851. Lowbush cranberry acts through DAF-16/FOXO signaling to promote increased lifespan and axon branching in AGING posterior touch receptor neurons
  3852. AGING-related changes of EEG synchronization during a visual working memory task
  3853. Upregulation of lncRNA-ATB by transforming growth factor β1 (TGF-β1) promotes migration and invasion of papillary thyroid carcinoma cells
  3854. The clearance effect of tetrahedral DNA nanostructures on senescent human dermal fibroblasts
  3855. GREM1 Improves the Regenerative Potential of AGING Cardiac Progenitor Cells
  3856. Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
  3857. Age-associated bimodal transcriptional drift reduces intergenic disparities in transcription
  3858. Inhibition by microbial metabolites of Chinese dark tea of age-related neurodegenerative disorders in senescence-accelerated mouse prone 8 (SAMP8) mice
  3859. Quantifying resilience of humans and other animals
  3860. Genomic instability and DNA replication defects in progeroid syndromes
  3861. Strategies targeting cellular senescence
  3862. Impaired cohesion and homologous recombination during replicative AGING in budding yeast
  3863. Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge
  3864. Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice
  3865. Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su (z) 2) negatively regulate longevity in Drosophila melanogaster
  3866. The relationship of mammal survivorship and body mass modeled by metabolic and vitality theories
  3867. Cellular senescence as a therapeutic target to improve renal transplantation outcome
  3868. Autophagy and the cell biology of age-related disease
  3869. Stem cells: AGING and transcriptional fingerprints
  3870. Does physical activity age wild animals?
  3871. Species comparison of liver proteomes reveals links to naked mole-rat longevity and human AGING
  3872. Extracellular RNA profiles with human age
  3873. NLRP3 inflammasome activation in inflammAGING
  3874. Physiological and Pathological Vascular AGING
  3875. Deficient mitochondrial biogenesis in IL-2 activated NK cells correlates with impaired PGC1-α upregulation in elderly humans
  3876. What is the ethics of ageing?
  3877. Sex differences in the response to dietary restriction in rodents
  3878. Protective mechanism of adipose-derived stem cells in remodelling of the skin stem cell niche during photoAGING
  3879. AGING-associated Changes in the DNA Methylome and Characteristics of the Epigenetic Clock
  3880. Differential stem cell AGING kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome
  3881. DNA methylation–based measures of biological AGING
  3882. Telomere maintenance during anterior regeneration and AGING in the freshwater annelid Aeolosoma viride
  3883. Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart
  3884. Telomere Length as Cardiovascular AGING Biomarker: JACC Review Topic of the Week
  3885. Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells
  3886. Mitochondrial dysfunction reduces yeast replicative lifespan by elevating RAS-dependent ROS production by the ER-localized NADPH oxidase Yno1
  3887. Identity noise and adipogenic traits characterize dermal fibroblast AGING
  3888. The relationship between telomere length and mortality risk in non-model vertebrate systems: a meta-analysis
  3889. Breaking the ceiling of human maximal life span
  3890. AGING-related compensated hypogonadism: Role of metabolomic analysis in physiopathological and therapeutic evaluation
  3891. The role of DNA‐PK in AGING and energy metabolism
  3892. Myeloid-derived suppressor cells at the intersection of inflammAGING and bone fragility
  3893. Structural similarity-based prediction of the potential active ingredients and mechanism of action of traditional Chinese medicine formulations used to anti …
  3894. Novel insights into the anti-AGING role of mitophagy
  3895. Usefulness of telomere length in DNA from human teeth for age estimation
  3896. Genomics: new light on Alzheimer’s disease research
  3897. Increased expression of long noncoding RNA HMMR-AS1 in epithelial ovarian cancer: an independent prognostic factor
  3898. Pyruvate protects against cellular senescence through the control of mitochondrial and lysosomal function in dermal fibroblasts
  3899. Mitochondrial oxidative stress and cardiac ageing
  3900. Protein synthesis and quality control in AGING
  3901. Assessment of the AGING of the Brown Adipose Tissue by 18F-FDG PET/CT ImAGING in the Progeria Mouse Model Lmna−/−
  3902. Mice with reduced expression of the telomere‐associated protein Ft1 develop p53‐sensitive progeroid traits
  3903. Pleiotropic effects of metformin: Shaping the microbiome to manage type 2 diabetes and postpone ageing
  3904. Spermidine ameliorates the neuronal AGING by improving the mitochondrial function in vitro
  3905. An osteopenic/osteoporotic phenotype delays alveolar bone repair
  3906. Application of biological age assessment of Chinese population in potential anti-ageing technology
  3907. Geriatric Rehabilitation 20
  3908. Mitochondrial metabolism and the age-associated cardiovascular diseases
  3909. The AGING lung: tissue telomere shortening in health and disease
  3910. SUMOylation, AGING and autophagy in neurodegeneration
  3911. GRK5–A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders
  3912. Impact of long-term RF-EMF on oxidative stress and neuroinflammation in AGING brains of C57BL/6 mice
  3913. Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk
  3914. Mitoproteomics: Tackling mitochondrial dysfunction in human disease
  3915. Leukocyte telomere length in patients with bipolar disorder: an updated meta-analysis and subgroup analysis by mood status
  3916. Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan
  3917. Clonal hematopoiesis and evolution to hematopoietic malignancies
  3918. Ultrastructural and molecular analysis of ribose-induced glycated reconstructed human skin
  3919. Recent advances: decoding Alzheimer’s disease with stem cells
  3920. Epigenetics and cardiovascular regenerative medicine in the elderly
  3921. Mitochondria, oxidative stress and the kynurenine system, with a focus on ageing and neuroprotection
  3922. Mesenchymal stem cell therapy for AGING frailty
  3923. JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the Drosophila testis
  3924. Age and age-related diseases: role of inflammation triggers and cytokines
  3925. Opposing action of hedgehog and insulin signaling balances proliferation and autophagy to determine follicle stem cell lifespan
  3926. Parallels in immunometabolic adipose tissue dysfunction with ageing and obesity
  3927. The therapeutic potential of metformin in neurodegenerative diseases
  3928. Transcriptome analysis reveals mechanisms of geroprotective effects of fucoxanthin in Drosophila
  3929. Autophagy maintains stem cells and intestinal homeostasis in Drosophila
  3930. Evaluating intrinsic and non-intrinsic cancer risk factors
  3931. Metformin is a direct SIRT1-activating compound: computational modeling and experimental validation
  3932. Integrating geriatric principles into critical care medicine: the time is now
  3933. The AGING heart
  3934. MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence, and angiogenic signaling
  3935. Osthole delays Tert-butyl hydroperoxide-induced premature senescence in neural stem cells
  3936. Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1
  3937. The role of telomeres in the mechanisms and evolution of life-history trade-offs and ageing
  3938. N-acetyl-l-cysteine attenuates oxidative damage and neurodegeneration in rat brain during AGING
  3939. Harnessing protease activity to improve cancer care
  3940. Physical activity and CVD in older adults: an expert’s perspective
  3941. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and AGING
  3942. Decipher reliable biomarkers of brain AGING by integrating literature-based evidence with interactome data
  3943. Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women
  3944. LncRNA PlncRNA-1 overexpression inhibits the growth of breast cancer by upregulating TGF-β1 and downregulating PHGDH
  3945. Physical activity and the development of visible age-related signs in the general population: a prospective cohort study
  3946. Microglia in neurological diseases: a road map to brain-disease dependent-inflammatory response
  3947. The telomerase complex directly controls hematopoietic stem cell differentiation and senescence in an induced pluripotent stem cell model of telomeropathy
  3948. Long-term dietary macronutrients and hepatic gene expression in AGING mice
  3949. High expression of the breast cancer susceptibility gene BRCA1 in long-lived termite kings
  3950. Low serum tryptophan levels as an indicator of global cognitive performance in nondemented women over 50 years of age
  3951. In vivo somatic cell reprogramming for tissue regeneration: The emerging role of the local microenvironment
  3952. Impact of stress on aged immune system compartments: Overview from fundamental to clinical data
  3953. Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence
  3954. Dynamical analysis of cellular ageing by modeling of gene regulatory network based attractor landscape
  3955. Repurposing proteostasis-modifying drugs to prevent or treat age-related dementia: a systematic review
  3956. Measures of biologic age in a community sample predict mortality and age-related disease: the Framingham Offspring Study
  3957. Free Radicals, Oxidants and Antioxidant Systems in Physiology and Disease
  3958. Operation of the permeability transition pore in rat heart mitochondria in AGING
  3959. Brain AGING in HIV-1 Infection
  3960. New insight in the molecular mechanisms of neurodegenerative disease
  3961. Emerging Connections: Synaptic Autophagy in Brain AGING and Disease
  3962. The Smurf transition: new insights on ageing from end-of-life studies in animal models
  3963. Inhibitory effect of vitamin C on intrinsic AGING in human dermal fibroblasts and hairless mice
  3964. Association of Prevotella enterotype with polysomnographic data in obstructive sleep apnea/hypopnea syndrome patients
  3965. The TORC1-Sch9 pathway as a crucial mediator of chronological lifespan in the yeast Saccharomyces cerevisiae
  3966. Knockout of tissue transglutaminase ameliorates TGFβ2-induced ocular hypertension: A novel therapeutic target for glaucoma?
  3967. Natural variations in yeast AGING reveal genetic and environmental factors
  3968. The Kruppel-like Factors in AGING and AGING Associated Pathology
  3969. Characterization of senescence of human adipose-derived stem cells after long-term expansion
  3970. Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function
  3971. Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial …
  3972. Sestrins are Gatekeepers in the Way from Stress to AGING and Disease
  3973. The Aplication of Topical Wharton’s Jelly Mesenchymal Stem Cell Conditioned Medium (Wjmsc-Cm) Inhibit the Increase in Expression of Matrix Metalloproteinase-1 …
  3974. Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of d-galactose
  3975. Factors Affecting the Occurrence of Complications in the Early Stages After Dental Implant Placement: A Retrospective Cohort Study
  3976. Physiological basis for sex-specific differences in longevity
  3977. ATP Synthase, a Target for Dementia and AGING?
  3978. Inosine improves cognitive function and decreases AGING-induced oxidative stress and neuroinflammation in aged female rats
  3979. Lung cancer in chronic obstructive pulmonary disease patients: importance of cellular senescence
  3980. The effects of mind-body exercise on cognitive performance in elderly: a systematic review and meta-analysis
  3981. Cutaneous infections in the mature patient
  3982. Widespread accumulation of ribosome-associated isolated 3′ UTRs in neuronal cell populations of the AGING brain
  3983. High-dimensional phenotyping identifies age-emergent cells in human mammary epithelia
  3984. Accelerated AGING induced by deficiency of Zmpste24 protects old mice to develop bleomycin-induced pulmonary fibrosis
  3985. The absence of tau prevents AGING-associated cognitive impairment by blocking mitochondrial permeability transition pore opening
  3986. The insulin/IGF-1, the sirtuin and the mTOR pathway. How alterations of these pathways could affect age-related diseases and lifespan.
  3987. Tissue iron is negatively correlated with TERC or TERT mRNA expression: a heterochronic parabiosis study in mice
  3988. AGING attenuates redox adaptive homeostasis and proteostasis in female mice exposed to traffic-derived nanoparticles (‘vehicular smog’)
  3989. Anti-AGING and Anti-aggregation Properties of Polyphenolic Compounds in C. elegans
  3990. Molecular basis of mitotic decline during human AGING
  3991. A virus-acquired host cytokine controls systemic AGING by antagonizing apoptosis
  3992. Proteoforms: methods of analysis and clinical prospects
  3993. Assistive ai for coping with memory loss
  3994. Bmal1-deficient mouse fibroblast cells do not provide premature cellular senescence in vitro
  3995. Age-Related Variations in Gene Expression Patterns of Renal Cell Carcinoma: Biological and Translational Implications
  3996. Ageing, cellular senescence and neurodegenerative disease
  3997. The good, the bad, and the ugly of ROS: new insights on AGING and AGING-related diseases from eukaryotic and prokaryotic model organisms
  3998. Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes
  3999. PPARs and metabolic disorders associated with challenged adipose tissue plasticity
  4000. Levels of histidine-rich glycoprotein in human blood predict accelerated AGING
  4001. AGING, telomere integrity, and antioxidant food
  4002. Lifelong calorie restriction affects indicators of colonic health in AGING C57Bl/6J mice
  4003. Immune Modulation and Its Role in AntiAGING
  4004. Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system
  4005. Computational methods for developing novel antiAGING interventions
  4006. Drug synergy slows AGING and improves healthspan through IGF and SREBP lipid signaling
  4007. Antiretroviral Drug Mediated Astrocyte Senescence as a Contributor to HIV-1-Associated Neurocognitive Disorders
  4008. The emerging role of lncRNAs in the regulation of cancer stem cells
  4009. Leukocyte Telomere Length and Cognitive Function in Older Adults
  4010. Understanding mechanisms to promote successful AGING in persons living with HIV
  4011. Current Approaches of Anti-inflammatory-Dependent AntiAGING Strategies
  4012. Dietary patterns and whole plant foods in AGING and disease
  4013. TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac AGING
  4014. Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration
  4015. Autophagy as a promoter of longevity: insights from model organisms
  4016. Disruption of adipokinetic hormone mediated energy homeostasis has subtle effects on physiology, behavior and lipid status during AGING in Drosophila
  4017. From Neurons to Transcription Factors: the Biological Regulation of AGING
  4018. Maximal strength training increases muscle force generating capacity and the anaerobic ATP synthesis flux without altering the cost of contraction in elderly
  4019. Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.
  4020. Role of glial immunity in lifespan determination: a Drosophila perspective
  4021. An Analysis of the effects of Mocs1 upregulation on lifespan in Drosophila melanogaster
  4022. Gene expression analysis reveals novel gene signatures between young and old adults in human prefrontal cortex
  4023. Hyperphosphatemia promotes senescence of myoblasts by impairing autophagy through ilk overexpression, a possible mechanism involved in sarcopenia
  4024. Multinutrient Approach to Slow Down Brain AGING and Related Neurodegenerative Disorders
  4025. Study of age-related changes in compensatory processes in the model of neurodegeneration of the nigrostriatal system in rats
  4026. AGING is an adaptation that selects in animals against disruption of homeostasis
  4027. Role of NLRP3-inflammasone in functional decline in physiological AGING. Implications for cardio-metabolic events.
  4028. Linking cellular proteostasis to yeast longevity
  4029. Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain
  4030. Oncogene-induced senescence: a double edged sword in cancer
  4031. Trend-analysis of dental hard-tissue conditions as function of tooth age
  4032. Genetic Ablation of p16INK4a Does Not Protect against Cellular Senescence in Mouse Models of Chronic Obstructive Pulmonary Disease/Emphysema
  4033. Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by AGING
  4034. Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells
  4035. Theories of Individual Ageing
  4036. Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres
  4037. Boosting ATM activity alleviates AGING and extends lifespan in a mouse model of progeria
  4038. Fernblock prevents dermal cell damage induced by visible and infrared a radiation
  4039. Alternative formats
  4040. European-wide studies on pro-inflammatory risk factors in early life and molecular markers of AGING
  4041. Timing of neuronal plasticity in development and AGING
  4042. PGC-1α protects RPE cells of the AGING retina against oxidative stress-induced degeneration through the regulation of senescence and mitochondrial quality control …
  4043. Epigenetic mechanisms regulating adaptive responses to targeted kinase inhibitors in cancer
  4044. Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration
  4045. Left Ventricular Diastolic Dysfunction in Hutchinson-Gilford Progeria Syndrome
  4046. Mitochondrial metabolism and AGING in yeast
  4047. Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death
  4048. LncRNA HOTAIR improves diabetic cardiomyopathy by increasing viability of cardiomyocytes through activation of the PI3K/Akt pathway
  4049. Srebp-1c-dependent metabolic remodeling of white adipose tissue by caloric restriction
  4050. MicroRNAs-103/107 regulate autophagy in the epidermis
  4051. Potentials of cellular reprogramming as a novel strategy for neuroregeneration
  4052. Cancer-free AGING: insights from Spalax ehrenbergi superspecies
  4053. Healthy ageing and the science of longevity in dogs. Part I: is grey the new gold?
  4054. Fertility, IVF and reproductive genetics
  4055. Quantitative phosphoproteomics reveals GTBP-1 regulating C. elegans lifespan at different environmental temperatures
  4056. Experimental models for AGING and their potential for novel drug discovery
  4057. Mitochondrial Dysfunction Underlies the Proinflammatory Phenotype of Multipotent Mesenchymal Stromal Cells from Atherosclerotic Individuals
  4058. Telomeric epigenetic response mediated by Gadd45a regulates stem cell AGING and lifespan
  4059. Impact of habitual physical activity and type of exercise on physical performance across ages in community-living people
  4060. Horizon meeting on cardiovascular physiology: Dedicated to Dr. Mike Sharratt
  4061. The role of the protein SNEVhPrp19/hPso4 in function and morphology of human dermal fibroblasts and human epidermal keratinocytes
  4062. Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
  4063. Premature brain AGING in humans exposed to maternal nutrient restriction during early gestation
  4064. Mitohormesis, an antiAGING paradigm
  4065. Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing
  4066. The inflammatory potential of the diet at midlife is associated with later healthy AGING in French adults
  4067. Protein quality control in the endoplasmic reticulum and cancer
  4068. Epigenetic Mechanisms in Osteoporosis
  4069. Telomere maintenance mechanisms in cancer
  4070. Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells
  4071. The emerging roles for telomerase in the central nervous system
  4072. Presynaptic neurodegeneration: CSP-α/DNAJC5 at the synaptic vesicle cycle and beyond
  4073. The effect of aerobic training with Citrus aurantium L. on Sirtuin 1 and peroxisome proliferator-activated receptor gamma coactivator 1-alpha gene expression …
  4074. From apparent to real age: gender, age, ethnic, makeup, and expression bias analysis in real age estimation
  4075. The Role of Noncoding RNAs in Genome Stability and AGING
  4076. Zinc-induced metallothionein in centenarian offspring from a large European population: the MARK-AGE project
  4077. Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly
  4078. Regulation of age-related decline by transcription factors and their crosstalk with the epigenome
  4079. ESRD-associated immune phenotype depends on dialysis modality and iron status: clinical implications
  4080. Physical activity attenuates the impact of poor physical, mental, and social health on total and cardiovascular mortality in older adults: a population-based prospective …
  4081. Altered expression of mitochondrial NAD+ carriers influences yeast chronological lifespan by modulating cytosolic and mitochondrial metabolism
  4082. Therapeutics of Stem Cell Treatment in Anti-AGING and Rejuvenation
  4083. TRAF-interacting protein with forkhead-associated domain (TIFA) transduces DNA damage–induced activation of NF-κB
  4084. Growing old, yet staying young: The role of telomeres in bats’ exceptional longevity
  4085. Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men
  4086. T cell epigenetic remodeling and accelerated epigenetic AGING are linked to long-term immune alterations in childhood cancer survivors
  4087. Catecholamine-induced senescence of endothelial cells and bone marrow cells promotes cardiac dysfunction in mice
  4088. The emerging role of follistatin under stresses and its implications in diseases
  4089. Mitophagy in cardiomyocytes and in platelets: a major mechanism of cardioprotection against ischemia/reperfusion injury
  4090. Chronic inflammation and sarcopenia: A regenerative cell therapy perspective
  4091. Applying parametric models to survival data: tradeoffs between statistical significance, biological plausibility, and common sense
  4092. Glucose intake hampers PKA-regulated HSP90 chaperone activity
  4093. Integrative analysis of global gene expression identifies opposite patterns of reactive astrogliosis in aged human prefrontal cortex
  4094. Leucine Exerts Lifespan Extension and Improvement in Three Types of Stress Resistance (Thermotolerance, Anti-Oxidation and Anti-UV Irradiation) in C …
  4095. Age associated decrease of sialin in salivary glands
  4096. An aged human heart tissue model showing age-related molecular and functional deterioration resembling the native heart
  4097. Loss of stemness, EMT, and supernumerary tooth formation in Cebpb−/− Runx2+/− murine incisors
  4098. Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: a multicenter cohort observational study
  4099. Molecular differences between human small intestine and colon stem and progenitor cells
  4100. Epigenetic modifications of the α-synuclein gene and relative protein content are affected by ageing and physical exercise in blood from healthy subjects
  4101. Marine derived xyloketal derivatives exhibit anti-stress and anti-ageing effects through HSF pathway in Caenorhabditis elegans
  4102. Elevated and correlated expressions of miR-24, miR-30d, miR-146a, and SFRP-4 in human abdominal adipose tissue play a role in adiposity and insulin …
  4103. Nicotinamide adenine dinucleotide (NAD+) and cell AGING
  4104. LncRNA ZEB1-AS1 expression in cancer prognosis: Review and meta-analysis
  4105. Comprehensive map of age-associated splicing changes across human tissues and their contributions to age-associated diseases
  4106. Anthropometric and dietary factors as predictors of DNA damage in obese women
  4107. Resveratrol counteracts bone loss via mitofilin-mediated osteogenic improvement of mesenchymal stem cells in senescence-accelerated mice
  4108. Asthma over the age of 65: all’s well that ends well
  4109. Ferrosenescence: the iron age of neurodegeneration?
  4110. Effect of a 12-month exercise intervention on leukocyte telomere length: Results from the ALPHA Trial
  4111. Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells
  4112. Putting a strain on diversity
  4113. Notch2 signaling maintains NSC quiescence in the murine ventricular-subventricular zone
  4114. Depletion of Ubiquilin induces an augmentation in soluble ubiquitinated Drosophila TDP-43 to drive neurotoxicity in the fly
  4115. Tuberculosis in the elderly: Why inflammation matters
  4116. Dietary restriction improves intestinal cellular fitness to enhance gut barrier function and lifespan in D. melanogaster
  4117. Oxidants produced by methylglyoxal-modified collagen trigger ER stress and apoptosis in skin fibroblasts
  4118. Medicine in Older Patients: Evidence Based?
  4119. Epigenetic drift of H3K27me3 in AGING links glycolysis to healthy longevity in Drosophila
  4120. Integrated analysis of the impact of age on genetic and clinical aspects of hepatocellular carcinoma
  4121. U1 snRNP alteration and neuronal cell cycle reentry in Alzheimer disease
  4122. Oxidative stress and mitochondrial dysfunction contributes to postoperative cognitive dysfunction in elderly rats
  4123. The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease
  4124. Long non-coding RNAs involved in metastasis of gastric cancer
  4125. ICAM-1 deficiency in the bone marrow niche impairs quiescence and repopulation of hematopoietic stem cells
  4126. Efficacy and durability of hyaluronic acid fillers for malar enhancement: A prospective, randomized, split-face clinical controlled trial
  4127. Intergenerational transfers and the older population
  4128. miR-200a modulates the expression of the DNA repair protein OGG1 playing a role in AGING of primary human keratinocytes
  4129. How do chaperones protect a cell’s proteins from oxidative damage?
  4130. Biological embedding of psychosocial stress over the life course
  4131. DNA methylation patterns separate senescence from transformation potential and indicate cancer risk
  4132. Glutathione as a Marker for Human Disease
  4133. The secretory phenotype of senescent astrocytes isolated from Wistar newborn rats changes with anti-inflammatory drugs, but does not have a short-term effect on …
  4134. Age-associated functional morphology of thyroid and its impact on the expression of vimentin, cytokeratins and VEGF. The role of nigella in refinement
  4135. The interplay between immunity and AGING in Drosophila
  4136. Identification and expression of carbonic anhydrase 2, myosin regulatory light chain 2 and selenium-binding protein 1 in zebrafish Danio rerio: Implication for age …
  4137. Janusz Ligęza
  4138. Why the UK needs a social policy on ageing
  4139. Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK …
  4140. Better Nutritional Status Is Positively Associated with mRNA Expression of SIRT1 in Community-Dwelling Older Adults in the Toledo Study for Healthy AGING
  4141. Colonoscopy in the very elderly
  4142. Advances and current challenges associated with the use of human induced pluripotent stem cells in modeling neurodegenerative disease
  4143. The emerging roles of microRNAs in stem cell AGING
  4144. Metabolite sensing and signaling in cell metabolism
  4145. Microglia polarization, gene-environment interactions and Wnt/β-catenin signaling: emerging roles of glia-neuron and glia-stem/neuroprogenitor crosstalk for …
  4146. Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism
  4147. Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition
  4148. Does physical activity age wild animals?
  4149. DNA damage, metabolism and AGING in pro-inflammatory T cells: Rheumatoid arthritis as a model system
  4150. Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
  4151. Mitochondrial tethers and their impact on lifespan in budding yeast
  4152. Taurine supplementation induces long-term beneficial effects on glucose homeostasis in ob/ob mice
  4153. Mitochondrial quality control mechanisms and the PHB (Prohibitin) complex
  4154. Antioxidant and oxidative stress: a mutual interplay in age-related diseases
  4155. Investigating the role of Sirtuins in cell reprogramming
  4156. Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti
  4157. Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2
  4158. Short-duration swimming exercise after myocardial infarction attenuates cardiac dysfunction and regulates mitochondrial quality control in aged mice
  4159. Nicotinamide improves aspects of healthspan, but not lifespan, in mice
  4160. Inhibition of oxidative stress in cholinergic projection neurons fully rescues AGING-associated olfactory circuit degeneration in Drosophila
  4161. Properties of the epigenetic clock and age acceleration
  4162. The Circadian Clock and the AGING Process
  4163. Involvement of MicroRNAs in the AGING-related decline of CD28 expression by human T cells
  4164. Mechanisms of vascular AGING: What can we learn from Hutchinson-Gilford progeria syndrome?
  4165. Weighing in on mTOR complex 2 signaling: the expanding role in cell metabolism
  4166. Correlates and aetiological factors associated with hedonic well-being among an ageing population of US men and women: secondary data analysis of a …
  4167. InflammAGING: a new immune–metabolic viewpoint for age-related diseases
  4168. Molecular mechanisms of intervertebral disc degeneration
  4169. Temporal integrative analysis of mRNA and microRNAs expression profiles and epigenetic alterations in female SAMP8, a model of age-related cognitive …
  4170. Circadian Mechanisms of Calorie Restriction in Delaying AGING
  4171. Aged kidney: can we protect it? Autophagy, mitochondria and mechanisms of ischemic preconditioning
  4172. Assessing the Effect of Epigenetic Dysregulation on Oncogenesis and Immunocompetence in a Mouse Model
  4173. Intermittent Fasting-Dietary Restriction as a Geroprotector
  4174. Age-Related Changes in the Expression of an Enhancer Reporter in the Mouse Brain
  4175. Relation of long-term patterns in caregiving activity and depressive symptoms to telomere length in older women
  4176. AGING of Human Mesenchymal Stem Cells
  4177. Autophagy gene overexpression in Saccharomyces cerevisiae perturbs subcellular organellar function and accumulates ROS to accelerate cell death with relevance …
  4178. Telomere length and its association with hippocampal gray matter volume in antipsychotic-naïve/free schizophrenia patients
  4179. The role of free radicals in autophagy regulation: implications for ageing
  4180. Effect of polyphenols from coffee and grape on gene expression in myoblasts
  4181. Senescent cell clearance by the immune system: Emerging therapeutic opportunities
  4182. Major Lifestyles and Phenotypes in AGING and Disease
  4183. Parity-dependent hemosiderin and lipofuscin accumulation in the reproductively aged mouse ovary
  4184. AGING pathology in sprague dawley rats: background lesions and comparative study between wild type and transgenic rats with neuronal overexpression of human …
  4185. mTORC inhibitors as broad-spectrum therapeutics for age-related diseases
  4186. Neurocognitive disorders and dehydration in older patients: clinical experience supports the hydromolecular hypothesis of dementia
  4187. Genotype and sex differences in longevity in transgenic mouse models of Alzheimer’s disease
  4188. Committed as a violent sexual predator in his 10th decade: A case study
  4189. Gonadal steroids
  4190. Impact of F1Fo-ATP-synthase dimer assembly factors on mitochondrial function and organismic AGING
  4191. Polyamine metabolism and gene methylation in conjunction with one-carbon metabolism
  4192. Effects of physiological overexpression of SIRT6 in metabolism and cancer
  4193. Clinical outcomes and prognostic factors in patients directly transferred to the intensive care unit from long-term care beds in institutions and hospitals: a …
  4194. Identification of Molecular Determinants of Cellular Senescence in Cancer and AGING
  4195. Molecular habituation’as a potential mechanism of gradual homeostatic loss with age
  4196. Non-senescent Hydra tolerates severe disturbances in the nuclear lamina
  4197. Holothuria scabra extracts possess anti-oxidant activity and promote stress resistance and lifespan extension in Caenorhabditis elegans
  4198. Age-related gene expression profiles of immature human oocytes
  4199. AGING Immunity: Monocyte Derived Dendritic Cell’s Metabolic Shift Associated with Human AGING
  4200. Sirtuins in mitochondrial stress: Indispensable helpers behind the scenes
  4201. LONELINESS AND DEPRESSION AMONG INSTITUTIONALIZED AND NON-INSTITUTIONALIZED ELDERS COMPARATIVE STUDY
  4202. Genetic and Pharmacological Regulation of Epigenetic AGING
  4203. The rate of telomere loss is related to maximum lifespan in birds
  4204. SIN-3 as a key determinant of lifespan and its sex dependent differential role on healthspan in Caenorhabditis elegans
  4205. The cost of intraoperative adverse events in abdominal and pelvic surgery: A systematic review
  4206. β-Arrestin based receptor signaling paradigms: potential therapeutic targets for complex age-related disorders
  4207. Heme oxygenase-1 deficiency affects bone marrow niche and triggers premature exhaustion of hematopoietic stem cells
  4208. Updates on old and weary haematopoiesis
  4209. Yeast replicative AGING leads to permanent cell cycle arrest in G1 effectuated by the start repressor Whi5
  4210. Yoga Meditation Lifestyle Intervention: Impact on Male Reproductive Health
  4211. La suplementación con té verde promueve la elongación de los telómeros de leucocitos en mujeres obesas
  4212. Transcriptional repression of high-mobility group box 2 by p21 in radiation-induced senescence
  4213. Age-dependent changes in transcription factor FOXO targeting in Drosophila melanogaster
  4214. Insights from large-scale cancer genome sequencing
  4215. CSA and CSB play a role in the response to DNA breaks
  4216. Is overall mortality the right composite endpoint in clinical trials of acute respiratory distress syndrome?
  4217. TRF1 as a major contributor for telomeres’ shortening in the context of obesity
  4218. Organoruthenium (II) complexes ameliorates oxidative stress and impedes the age associated deterioration in Caenorhabditis elegans through JNK-1/DAF-16 …
  4219. Relative bioavailability of Silybin A and Silybin B from 2 multiconstituent dietary supplement formulations containing milk thistle extract: A single-dose study
  4220. Association of DNA methylation-based biological age with health risk factors and overall and cause-specific mortality
  4221. Healthy at 100: Genetic factors and phenotypes associated with healthy AGING and longevity
  4222. Insulin Signaling-independent Activation of DAF-16 Shapes the Transcriptome during Normal AGING
  4223. A framework for uncovering the roles of calories and macronutrients in health and AGING
  4224. Manipulation of mitochondrial function by polyphenols for new treatment strategies
  4225. An oral combination of vitamins A, C, E, and Mg++ improves auditory thresholds in age-related hearing loss
  4226. Altered monocyte phenotypes but not impaired peripheral T cell immunity may explain susceptibility of the elderly to develop tuberculosis
  4227. Dominance rank-associated gene expression is widespread, sex-specific, and a precursor to high social status in wild male baboons
  4228. p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice
  4229. Abnormal nuclear morphology is independent of longevity in a zmpste24-deficient fish model of Hutchinson-Gilford progeria syndrome (HGPS)
  4230. Endothelial cell senescence in the pathogenesis of endothelial dysfunction
  4231. Identification of 170 new long noncoding RNAs in Schistosoma mansoni
  4232. Roles of non-coding RNAs in transcriptional regulation
  4233. Changes of immunoglobulin G glycosylation with age
  4234. Does dietary nitrate say NO to cardiovascular ageing? Current evidence and implications for research
  4235. Explaining cancer: Finding order in disorder
  4236. Effects of boron-containing compounds on cardiovascular disease risk factors–a review
  4237. Cocaine use may induce telomere shortening in individuals with HIV infection
  4238. Reduced cellularity of bone marrow in multiple sclerosis with decreased MSC expansion potential and premature ageing in vitro
  4239. Zmynd17 controls muscle mitochondrial quality and whole‐body metabolism
  4240. Role of autophagy in proteostasis: friend and foe in cardiac diseases
  4241. Polymeric microsphere-facilitated site-specific delivery of quercetin prevents senescence of pancreatic islets in vivo and improves transplantation outcomes in mouse …
  4242. Loss of CD31 receptor in CD4+ and CD8+ T-cell subsets in children with primary hypertension is associated with hypertension severity and hypertensive target organ …
  4243. Interaction of neuropeptide F and diet levels effects carbonyl levels in grasshoppers
  4244. Ub and down: ubiquitin exercise for the elderly
  4245. Swimming exercise and transient food deprivation in Caenorhabditis elegans promote mitochondrial maintenance and protect against chemical-induced …
  4246. Reduced expression of C/EBPβ-LIP extends health and lifespan in mice
  4247. Metabolomics: State-of-the-Art Technologies and Applications on Drosophila melanogaster
  4248. Long Non-Coding RNAs in Neuronal AGING.
  4249. Healthy ageing: the natural consequences of good nutrition—a conference report
  4250. Female Reproductive AGING: From consequences to Mechanisms, Markers, and Treatments
  4251. The potential of non-myeloablative heterochronous autologous hematopoietic stem cell transplantation for extending a healthy life span
  4252. Pathological modelling of pigmentation disorders associated with Hutchinson-Gilford progeria syndrome (HGPS) revealed an impaired melanogenesis …
  4253. Non-developmental dimensions of adult regeneration in Hydra
  4254. Cancer Imprints an Increased PARP-1 and p53-Dependent Resistance to Oxidative Stress on Lymphocytes of Patients That Later Develop Alzheimer’s …
  4255. Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells
  4256. Role of Nutraceuticals in Modulation of Gut-Brain Axis in Elderly Persons
  4257. Idiopathic pulmonary fibrosis: pathogenesis and management
  4258. Plasticity of lifelong calorie‐restricted C57 BL/6J mice in adapting to a medium‐fat diet intervention at old age
  4259. A population neuroscience approach to the study of cerebral small vessel disease in midlife and late life: an invited review
  4260. Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice
  4261. The role of melatonin, a multitasking molecule, in retarding the processes of ageing
  4262. Shelterin differentially respond to oxidative stress induced by TiO2-NPs and regulate telomere length in human hepatocytes and hepatocarcinoma cells in vitro
  4263. The effects of graded levels of calorie restriction: X. Transcriptomic responses of epididymal adipose tissue
  4264. Cellular regulation of amyloid formation in AGING and disease
  4265. Gender and sex differences in adipose tissue
  4266. The influence and impact of ageing and immunosenescence (ISC) on adaptive immunity during multiple sclerosis (MS) and the animal counterpart experimental …
  4267. Targeting oxidatively induced DNA damage response in cancer: opportunities for novel cancer therapies
  4268. Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals
  4269. Mitochondrial dysfunction in metabolism and ageing: shared mechanisms and outcomes?
  4270. Metabolic determinants of longevity: dietary supplementation and mitochondria
  4271. Increased senescent CD8+ T cells in the peripheral blood mononuclear cells of Behçet’s disease patients
  4272. Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
  4273. Studies on the Mechanisms of DNA Damage Repair in Human Neurons
  4274. Parity dependent hemosiderin and lipofuscin accumulation in the reproductively aged mouse ovary
  4275. Extension of life span in laboratory mice
  4276. IAPP/amylin and β-cell failure: implication of the risk factors of type 2 diabetes
  4277. Metabotypes with elevated protein and lipid catabolism and inflammation precede clinical mastitis in prepartal transition dairy cows
  4278. Increasing neural stem cell division asymmetry and quiescence are predicted to contribute to the age-related decline in neurogenesis
  4279. Higher spermidine intake is linked to lower mortality: a prospective population-based study
  4280. Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation
  4281. MYBL2 supports DNA double strand break repair in hematopoietic stem cells
  4282. Evolutionarily adapted hormesis-inducing stressors can be a practical solution to mitigate harmful effects of chronic exposure to low dose chemical mixtures
  4283. Harnessing lysosomal pH through PLGA nanoemulsion as a treatment of lysosomal-related neurodegenerative diseases
  4284. Estimates of the heritability of human longevity are substantially inflated due to assortative mating
  4285. Environmental conditions shape the temporal pattern of investment in reproduction and survival
  4286. Ubisol-Q 10 (a nanomicellar water-soluble formulation of CoQ 10) treatment inhibits Alzheimer-type behavioral and pathological symptoms in a double transgenic …
  4287. Long non-coding RNA linc-ITGB1 promotes cell proliferation, migration, and invasion in human hepatoma carcinoma by up-regulating ROCK1
  4288. The consequences of mutator-driven mutagenesis and analysis of lifespan extending compounds using outgrowth analysis and replicative lifespan in Saccharomyces …
  4289. Role of Human Endogenous Retrovirus type K (HERV-K) in immunosenescence: RNA-seq based transcriptomic analysis
  4290. The physiology of homeoprotein transduction
  4291. Effect of dietary additives on intestinal permeability in both Drosophila and a human cell co-culture
  4292. DNA damage induced by human CD40 ligand mutant promotes senescence and induces demethylation of GATA4 in lung cancer
  4293. Age-related response to an acute innate immune challenge in mice: proteomics reveals a telomere maintenance-related cost
  4294. Impact of a shift work-like lighting schedule on the functioning of the circadian system in the short-lived fish Nothobranchius furzeri
  4295. Suboptimal extracellular pH values alter DNA damage response to induced double‐strand breaks
  4296. The combination of NAD+-dependent deacetylase gene deletion and the interruption of gluconeogenesis causes increased glucose metabolism in budding …
  4297. Temporal dynamics of microbiota before and after host death
  4298. Treatment outcomes of tuberculosis at Asella Teaching Hospital, Ethiopia: ten years’ retrospective aggregated data
  4299. Mitochondria reorganization upon proliferation arrest predicts individual yeast cell fate
  4300. Nutrition and inflammation: are centenarians similar to individuals on calorie-restricted diets?
  4301. Transcriptional profiling identifies strain-specific effects of caloric restriction and opposite responses in human and mouse white adipose tissue
  4302. Hypothalamic mitochondrial dysfunction as a target in obesity and metabolic disease
  4303. Using CRISPR/dCas9 to Dissect the Role of Ribosomal DNA in Cellular Growth and AGING in Saccharomyces cerevisiae
  4304. Modeling neuropsychiatric and neurodegenerative diseases with induced pluripotent stem cells
  4305. Biphasic regulation of spindle assembly checkpoint by low and high concentrations of resveratrol leads to the opposite effect on chromosomal instability
  4306. The proteome of neurofilament-containing protein aggregates in blood
  4307. Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
  4308. Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: a multicenter cohort observational study
  4309. Rejuvenation of the aged neuromuscular junction by exercise
  4310. Role of miRNA in the regulatory mechanisms of estrogens in cardiovascular ageing
  4311. Identifying the critical gaps in research on sex differences in metabolism across the life span
  4312. Intervertebral Disc Inflammation: The Effect Of Il-1ra Deficiency On Development, AGING And Injury Of The Murine Caudal Intervertebral Disc
  4313. Telomerase Activator 65 (TA-65) Favorably Affects Parameters of Metabolic Syndrome-A Pilot Study
  4314. The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer
  4315. Integrative approaches to cognitive decline.
  4316. Pseudomonas aeruginosa induces cellular senescence in lung tissue at the early stage of two-hit septic mice
  4317. Retracted: Ananas sativa increases longevity through oxidative stress resistance in Drosophila melanogaster
  4318. RETRACTION: ANANAS SATIVA INCREASES LONGEVITY THROUGH OXIDATIVE STRESS RESISTANCE IN DROSOPHILA MELANOGASTER
  4319. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11
  4320. Genetic code expansion in animals
  4321. Senescence of multicellular individuals: imbalance of epigenetic and non-epigenetic information in histone modifications
  4322. Upregulation of dNTP levels after telomerase inactivation influences telomerase-independent telomere maintenance pathway choice in Saccharomyces cerevisiae
  4323. Epigenetic modulation of vascular diseases: assessing the evidence and exploring the opportunities
  4324. Metabolic changes in primary, secondary, and lipid metabolism in tobacco leaf in response to topping
  4325. A new approach to treating neurodegenerative otologic disorders
  4326. Physical activity attenuates total and cardiovascular mortality associated with physical disability: a national cohort of older adults
  4327. Hallmarks of AGING: an autophagic perspective
  4328. Hallmarks of AGING in the liver
  4329. Hallmarks of senescence and AGING
  4330. Redox regulation by NRF2 in AGING and disease
  4331. From molecular promise to preclinical results: HDAC inhibitors in the race for healthy AGING drugs
  4332. Proteostasis and Energetics as Proteome Hallmarks of AGING and Influenza Challenge in Pulmonary Disease
  4333. The hallmarks of ferroptosis
  4334. The AGING lung and idiopathic pulmonary fibrosis
  4335. Obesity may accelerate the AGING process
  4336. The epigenetics of AGING in invertebrates
  4337. Harnessing cellular AGING in human stem cell models of amyotrophic lateral sclerosis
  4338. Autophagic control of skin AGING
  4339. EPIGENETIC PROFILES OF BIOLOGICAL AGING HALLMARKS
  4340. Time for the systems-level integration of AGING: resilience enhancing strategies to prevent Alzheimer’s disease
  4341. A defined human AGING phenome
  4342. Incomplete healing as a cause of AGING: the role of mitochondria and the cell danger response
  4343. Epigenetic biomarkers of AGING
  4344. An overview of the molecular and cellular biomarkers of AGING
  4345. Models and studies of AGING: Executive summary of a report from the U13 conference series
  4346. Epigenetic clock: just a convenient marker or an active driver of AGING?
  4347. Senotherapeutics: emerging strategy for healthy AGING and age-related disease
  4348. Accelerated lung AGING and chronic obstructive pulmonary disease
  4349. Mitochondria and AGING—The role of exercise as a countermeasure
  4350. Mitochondrial dysfunction and AGING: Insights from the analysis of extracellular vesicles
  4351. Telomere shortening as a hallmark of stem cell senescence
  4352. Exposure to environmental pollutants and their association with biomarkers of AGING: A multipollutant approach
  4353. Proteostasis collapse, a hallmark of AGING, hinders the chaperone-Start network and arrests cells in G1
  4354. Are There Common Mechanisms Between the Hutchinson–Gilford Progeria Syndrome and Natural AGING?
  4355. In silico clinical trials for anti-AGING therapies
  4356. In search of an AGING antidote
  4357. An atlas of the AGING lung mapped by single cell transcriptomics and deep tissue proteomics
  4358. The genetics of AGING: a vertebrate perspective
  4359. Approaches towards longevity: reprogramming, senolysis, and improved mitotic competence as anti-AGING therapies
  4360. DNA METHYLATION: CAUSE OR CONSEQUENCE OF AGING?
  4361. SYSTEMS-LEVEL MODELING OF BIOLOGICAL AND MOLECULAR AGING CHANGES OVER TIME
  4362. Developments in molecular epidemiology of AGING
  4363. Special Issue “Anti-AGING Properties of Natural Compounds”
  4364. Molecular Mechanisms Underlying Cardiometabolic Disease in AGING
  4365. Mechanisms and Late-Life Intervention of AGING
  4366. Molecular mechanisms underlying cardiometabolic disease in AGING
  4367. DNA break-induced epigenetic drift as a cause of mammalian AGING
  4368. Chaperone-mediated autophagy is a cytoprotective response of photoreceptors during AGING and retinal diseases.
  4369. Partial Reprogramming: A Shortcut to Rejuvenation
  4370. www. AGING-us. com AGING 2019, Vol. 11, Advance
  4371. Interplay between nutrient-sensing molecules during AGING and longevity
  4372. MicroRNAs and the genetic nexus of brain AGING, neuroinflammation, neurodegeneration, and brain trauma
  4373. Senescence in the lung: is this getting old?
  4374. Role of HMSG2 mediated FAO deficiency in IPF pathogenesis
  4375. ESPO/BIOLOGICAL SCIENCES SECTION SYMPOSIUM: EMERGING INSIGHTS IN INTERACTIONS AND NETWORKS IN THE BIOLOGY OF AGING DEVELOPING C …
  4376. Comparative analysis of epigenetic AGING clocks from CpG characteristics to functional associations
  4377. DEVELOPMENT OF EPIGENETIC MEASURES FOR GEROSCIENCE CLINICAL TRIALS
  4378. Re:“Decreased Levels of Anti-AGING Klotho in Obstructive Sleep Apnea” by Pákó et al.(Rejuvenation Res 2019 [Epub ahead of print]; DOI: 10.1089/rej. 2019.2183)
  4379. Preclinical research of Dihydromyricetin for brain AGING and neurodegenerative diseases
  4380. Interleukin-37 improves AGING-associated declines in adaptive immunity leading to enhanced suppression of Ph+ leukemia
  4381. Juel Rasmussen Group
  4382. Time for a new strategy in the war on Alzheimer’s disease
  4383. KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone AGING via condensin-mediated heterochromatin reorganization
  4384. Response to Rizza and Filomenia re:“Regulation of S-Nitrosylation in AGING and Senescence”
  4385. Role of hypothalamus in AGING and its underlying cellular mechanisms
  4386. The role of DNA repair in cellular AGING process
  4387. Cortical network dynamics are coupled with cognitive AGING in rats
  4388. Implications of AGING in plastic surgery
  4389. Environmental factors in successful AGING: the potential impact of air pollution
  4390. AGING by pollutants: Introducing the AGING dose (AD) 50
  4391. Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in AGING-related disorders
  4392. Hydralazine Improves Mitochondrial Function via SIRT1/SIRT5 Activation and Protects against Glucose Toxicity
  4393. Mitophagy and oxidation status of mitochondria in Idiopathic Pulmonary Fibrosis (IPF) macrophages: a study in bronchoalveolar lavage fluid (BALF)
  4394. Transient non-integrative nuclear reprogramming promotes multifaceted reversal of AGING in human cells
  4395. OPCs on a Diet: A Youthful Serving of Remyelination
  4396. Epigenome-wide association study of leukocyte telomere length
  4397. Late Breaking Abstract-WNT/ß-catenin signaling induces cellular senescence in lung alveolar epithelial cells
  4398. Decelerating ageing and biological clocks by autophagy
  4399. Genomic and Epigenomic Potential With Age: Genome, Epigenome, and the Epigenetic Clock
  4400. Metformin restores CNS remyelination capacity by rejuvenating aged stem cells
  4401. Telomere abnormalities in the pathobiology of idiopathic pulmonary fibrosis
  4402. Measuring AGING and identifying AGING phenotypes in cancer survivors
  4403. From powerhouse to perpetrator—mitochondria in health and disease
  4404. Modulating AGING and AGING-related Symptoms Using Endogenous Small Molecules
  4405. G protein-coupled receptor systems and their role in cellular senescence
  4406. Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescence
  4407. PANORAMIC VIEW OF ANTI-AGING PROBLEMS: FROM A CELL TO THE PERSONAL PRODUCT
  4408. Accumulation of damaged mitochondria in alveolar macrophages with reduced OXPHOS related gene expression in IPF
  4409. The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline
  4410. Towards a unified mechanistic theory of AGING
  4411. A multi-institutional comparison of younger and older adults with sickle cell disease
  4412. Ageing as a risk factor for neurodegenerative disease
  4413. GRSF1 is an age-related regulator of senescence
  4414. Rapamycin and Alzheimer’s disease: time for a clinical trial?
  4415. SA-β-galactosidase-based screening assay for the identification of senotherapeutic drugs
  4416. Studying Werner syndrome to elucidate mechanisms and therapeutics of human AGING and age-related diseases
  4417. Inflamm-AGING of hematopoietic stem cells
  4418. Mechanisms of cellular rejuvenation
  4419. Healthy AGING: a bibliometric analysis of the literature
  4420. Chronic stress exposure and daily stress appraisals relate to biological AGING marker p16INK4a
  4421. Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites
  4422. Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
  4423. Immunosenescence: the potential role of myeloid-derived suppressor cells (MDSC) in age-related immune deficiency
  4424. Plausible links between metabolic networks, stem cells, and longevity
  4425. The role of pathological AGING in cardiac and pulmonary fibrosis
  4426. ER stress links AGING to sporadic ALS
  4427. Maximizing longevity and healthspan: multiple approaches all converging on autophagy
  4428. Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic …
  4429. KMT 1 family methyltransferases regulate heterochromatin–nuclear periphery tethering via histone and non‐histone protein methylation
  4430. Independent and combined effects of telomere shortening and mtDNA4977 deletion on long-term outcomes of patients with coronary artery disease
  4431. Hypoxia and AGING
  4432. It is Time to Embrace 21st-Century Medicine
  4433. Potential role of E4orf1 protein in AGING-associated impairment in glycemic control
  4434. Fenofibrate, a peroxisome proliferator-activated receptor alpha, is a novel molecule with senolytic and autophagy activity for cartilage degeneration and osteoarthritis
  4435. Single-cell transcriptomic profiling of the AGING mouse brain
  4436. Breast cancer treatment and its effects on AGING
  4437. Astrocyte senescence: evidence and significance
  4438. Genomics of AGING and Longevity
  4439. STING SNP R293Q is associated with a decreased risk of AGING-related diseases
  4440. Mitochondrial dysfunction in AGING and cancer
  4441. Embrace the fat when getting old
  4442. Psychological wellbeing and healthy AGING: focus on telomeres
  4443. Drugs that target AGING: how do we discover them?
  4444. The role of lipids in AGING-related metabolic changes
  4445. Biomarkers of DNA damage in COPD patients undergoing pulmonary rehabilitation: Integrating clinical parameters with genomic profiling
  4446. mTOR as a central regulator of lifespan and AGING
  4447. Epigenetic mechanisms in cognitive impairment linked to AGING and Alzheimer’s disease
  4448. Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis
  4449. Brain organoids: a next step for humanized Alzheimer’s disease models?
  4450. Lipid assemblies at the crossroads of AGING, proteostasis, and neurodegeneration
  4451. Response kinetics reveal novel features of ageing in murine T cells
  4452. EXISTING STRATEGIES FOR ELECTRONIC DATA COLLECTION BY ELDER ABUSE MULTI-DISCIPLINARY TEAMS
  4453. The impact of caloric restriction on the epigenetic signatures of AGING
  4454. Re:“Regulation of S-Nitrosylation in AGING and Senescence” by Larrick and Mendelsohn (Rejuvenation Res 2019; 22: 171–174)
  4455. What can yeast tell us about AGING modulation by bioactive substances in functional food
  4456. NAD+ Metabolism in AGING and Cancer
  4457. LeverAGING budding yeast Saccharomyces cerevisiae for discovering AGING modulation substances for functional food
  4458. Hereditary syndromes with signs of premature AGING
  4459. Human Telomerase M-RNA Rescues Cellular Functions, Gene Regulation, and Chromatin Structure in Progeria Ipsc-Derived Endothelial Cells
  4460. Genetic pathways of AGING and their relevance in the dog as a natural model of human AGING
  4461. Noncoding RNA: AGING well with Norad
  4462. Geroscience and the challenges of AGING societies
  4463. Transcriptional heterogeneity of fibroblasts is a hallmark of the AGING heart
  4464. Toward a unified theory of AGING and regeneration
  4465. What Is the Exposome and How It Can Help Research on Air Pollution
  4466. Are we ill because we age?
  4467. The epigenetics of stem cell AGING comes of age
  4468. Age and poverty status alter the coding and noncoding transcriptome
  4469. Senolytics and senostatics: a two-pronged approach to target cellular senescence for delaying AGING and age-related diseases
  4470. Are we nearing the extinction of Gerentology?
  4471. MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage
  4472. Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice
  4473. Murine single-cell RNA-seq reveals cell-identity-and tissue-specific trajectories of AGING
  4474. Targeting senescent cells: Approaches, opportunities, challenges
  4475. Circular RNA involvement in AGING: an emerging player with great potential
  4476. The function of lncRNAs in AGING-related diseases and 3D genome
  4477. Characterization of senescence biomarkers in rheumatoid arthritis: relevance to disease progression
  4478. New Insights into Chronological Mobility of Retrotransposons In Vivo
  4479. To the freezers! Stored biospecimens from human randomized trials are an important new direction for studies of biological AGING
  4480. Comparability of biological AGING measures in the National Health and Nutrition Examination Study, 1999–2002
  4481. Neuronal O-GlcNAcylation improves cognitive function in the aged mouse brain
  4482. Exosomes, cancer’s little army
  4483. Latest advances in AGING research and drug discovery
  4484. Pulmonary diseases and ageing
  4485. Introductory Chapter: DNA Repair in Human Cells-A Daily Challenge
  4486. A novel pyrazolopyrimidine ligand of human PGK1 and stress sensor DJ1 modulates the shelterin complex and telomere length regulation
  4487. NADPH oxidases and AGING models of lung fibrosis
  4488. Quest for Bioactive Compounds in Our Diet with Anti-Ageing and Anti-Aggregation Properties
  4489. Circulating miRNAs in Successful and Unsuccessful AGING. A mini-review
  4490. Epigenetics of AGING and Cancer: A Comprehensive Look
  4491. Dissecting AGING and senescence—current concepts and open lessons
  4492. Alternate day fasting improves physiological and molecular markers of AGING in healthy, non-obese humans
  4493. The consequences of ageing, progeroid syndromes and cellular senescence on mechanotransduction and the nucleus
  4494. Epigenetic AGING clocks in ecology and evolution
  4495. Current state of saliva biomarkers for AGING and Alzheimer’s disease
  4496. Partial reprogramming as a therapeutic approach for heart disease: A state‐of‐the‐art review
  4497. Telomere and its role in the AGING pathways: telomere shortening, cell senescence and mitochondria dysfunction
  4498. Deconstructing age reprogramming
  4499. TGF-β signaling in cellular senescence and AGING-related pathology
  4500. Cellular senescence in bone
  4501. On the fly: recent progress on autophagy and AGING in Drosophila
  4502. Elevating acetyl-CoA levels reduces aspects of brain AGING
  4503. Emerging insights into the metabolic alterations in AGING using metabolomics
  4504. Socio-Economic Position Under the Microscope: Getting ‘Under the Skin’and into the Cells
  4505. Future cell and gene therapy for osteoarthritis (OA): potential for using mammalian protein production platforms, irradiated and transfected protein packAGING …
  4506. Nutrient sensing and redox balance: GCN2 as a new integrator in AGING
  4507. AGING, lifestyle and dementia
  4508. Lipotoxicity, AGING, and muscle contractility: does fiber type matter?
  4509. Plasma-based strategies for therapeutic modulation of brain AGING
  4510. Epigenomic drivers of immune dysfunction in AGING
  4511. Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the …
  4512. Mice with hyper-long telomeres show less metabolic AGING and longer lifespans
  4513. PHYTOCHEMICALS AS PROSPECTIVE HUMAN ANTI-AGING COMPOUNDS
  4514. Of AGING mice and men: gait speed decline is a translatable trait, with species-specific underlying properties
  4515. Population Epigenetics and AGING
  4516. Epigenetics and AGING
  4517. Recombinant buckwheat trypsin inhibitor improves the protein and mitochondria homeostasis in Caenorhabditis elegans model of AGING and age-related disease
  4518. Invertebrate and vertebrate models in AGING research.
  4519. Sex differences in the AGING human heart: decreased sirtuins, pro-inflammatory shift and reduced anti-oxidative defense
  4520. SIRT2 functions in AGING, autophagy, and apoptosis in post-maturation bovine oocytes
  4521. The effect of exclusive olive oil consumption on successful AGING: a combined analysis of the ATTICA and MEDIS epidemiological studies
  4522. Cell senescence in lupus
  4523. KMT1/Suv39 methyltransferase family regulates peripheral heterochromatin tethering via histone and non-histone protein methylations
  4524. NAD+ in brain AGING and neurodegenerative disorders
  4525. Epigenetic clock analysis of blood samples from Japanese schizophrenia patients
  4526. A triple drug combination targeting components of the nutrient-sensing network maximizes longevity
  4527. Autophagy as a beacon and sentry for AGING stem cells
  4528. DESIGNING TECHNOLOGY TO SUPPORT HEALTHCARE FOR AGING ADULTS
  4529. The Cambridge handbook of successful AGING
  4530. Is Nature our Best Assurance of Healthy Ageing? Lessons from age-resilient animal species
  4531. Epigenetic clock and relative telomere length represent largely different aspects of AGING in the Berlin AGING Study II (BASE-II)
  4532. Nutrigenomics as a tool to study the impact of diet on AGING and age-related diseases: the Drosophila approach
  4533. Intracellular heat shock protein 70 deficiency in pulmonary fibrosis
  4534. Cognitive and Brain AGING: Interventions to Promote Well-Being in Old Age
  4535. Cognitive AGING is not created equally: Differentiating unique cognitive phenotypes in “normal” adults
  4536. What AGING with HIV means in the year 2019
  4537. Proteasome activation to combat proteotoxicity
  4538. Mutat Res Gen Tox En
  4539. Chronic obstructive pulmonary disease as a main factor of premature AGING
  4540. Breast cancer risk in a rapidly AGING population: advances and approaches to study the AGING tissue microenvironment
  4541. Identification of key genes and transcription factors in AGING mesenchymal stem cells by DNA microarray data
  4542. AGING and the immune system: the impact of immunosenescence on viral infection, immunity and vaccine immunogenicity
  4543. Lactobacillus Strains Alleviated AGING Symptoms and AGING-Induced Metabolic Disorders in Aged Rats
  4544. Acceleration of β cell AGING determines diabetes and senolysis improves disease outcomes
  4545. The microbiome and AGING
  4546. Emerging senolytic agents derived from natural products
  4547. Remodeling of bone marrow hematopoietic stem cell niches promotes myeloid cell expansion during premature or physiological AGING
  4548. Allogeneic mesenchymal stem cell therapy: a regenerative medicine approach to geroscience
  4549. Mitochondrial dysfunction in the AGING retina
  4550. Molecular mechanisms of AGING: the role of oxidative stress and epigenetic modifications
  4551. Cellular senescence as a mechanism and target in chronic lung diseases
  4552. Oxidative stress: eustress and distress in redox homeostasis
  4553. COPD as a Disease of Immunosenescence
  4554. Dynamic DNA methylation during AGING: A “prophet” of age-related outcomes
  4555. Epigenetic changes during AGING and their reprogramming potential
  4556. Topical rapamycin reduces markers of senescence and AGING in human skin: an exploratory, prospective, randomized trial
  4557. Effects of AGING and diet on cardioprotection and cardiometabolic risk markers
  4558. Characterizing the Induction of Senescence by Tau and Beta-Amyloid in Rat Astrocytes
  4559. Classical monocytes from older adults maintain capacity for metabolic compensation during glucose deprivation and lipopolysaccharide stimulation
  4560. Age-related alterations affecting the chondrogenic differentiation of synovial fluid mesenchymal stromal cells in an equine model
  4561. Roles of Telomeres and Telomerase in AGING
  4562. The Origins of Ageing
  4563. The cGAS/STING pathway: a sensor of senescence-associated DNA damage and trigger of inflammation in early age-related macular degeneration
  4564. Role of nicotinamide in genomic stability and skin cancer chemoprevention
  4565. Negative conditioning of mitochondrial dysfunction in age-related neurodegenerative diseases
  4566. Programmed (Adaptive) AGING Theories
  4567. Sargassum fusiforme fucoidan SP2 extends the lifespan of Drosophila melanogaster by upregulating the Nrf2-mediated antioxidant signaling pathway
  4568. Nucleolar and ribosomal dysfunction—a common pathomechanism in childhood progerias?
  4569. Plant-rich dietary patterns, plant foods and nutrients, and telomere length
  4570. Relationships between ion channels, mitochondrial functions and inflammation in human AGING
  4571. Basic and translational AGING research in China: present and future
  4572. Multidimensional Proteomics Identifies Declines in Protein Homeostasis and Mitochondria as Early Signals for Normal AGING and Age-associated Disease in …
  4573. Impaired proteostasis during skeletal muscle AGING
  4574. Pairwise combinations of chemical compounds that delay yeast chronological AGING through different signaling pathways display synergistic effects on the …
  4575. Blood autophagy defect causes accelerated non-hematopoietic organ AGING
  4576. Turning back time with emerging rejuvenation strategies
  4577. Viewpoint on the role of tissue maintenance in ageing: focus on biomarkers of bone, cartilage, muscle, and brain tissue maintenance
  4578. How to measure population AGING? The answer is less than obvious: a review
  4579. Rapamycin modulates tissue AGING and lifespan independently of the gut microbiota in Drosophila
  4580. DNA damage repair and DNA methylation in the kidney
  4581. Impact of AGING on bone, marrow and their interactions
  4582. Age-related gene and miRNA expression changes in airways of healthy individuals
  4583. AGING triggers H3K27 trimethylation hoarding in the chromatin of Nothobranchius furzeri skeletal muscle
  4584. microRNAs in the functional defects of skin AGING
  4585. Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults
  4586. IMPACT OF WELLBEING ON QUALITY OF LIFE OF AGING POPULATION IN PAKISTAN: EVIDENCE FROM KARACHI.
  4587. Functional genomics of dietary restriction and longevity in yeast
  4588. The murine transcriptome reveals global AGING nodes with organ-specific phase and amplitude
  4589. Association of 10-Year C-reactive protein trajectories with markers of healthy AGING: Findings from the English Longitudinal Study of AGING
  4590. DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during AGING
  4591. Deciphering the metabolic secret of longevity through the analysis of metabolic response to stress on long-lived species
  4592. Yeast at the forefront of research on ageing and age-related diseases
  4593. Toward understanding genomic instability, mitochondrial dysfunction and AGING
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