View All Products
0
Home
Products
Which Blend is Best for Me?
All Blends
Samples
Combos
Testimonials
About
Resources
88/8: Extreme Weightloss Protocol
Ultimate Dry Fasting Resource
Science
Ingredients
Mailing List
Contact
Shipping
Gavin
Text Sign Up
Telegram Portal
My Account
Home
>
Blog
>
FNDC5
FNDC5
FNDC5/irisin is not only a myokine but also an adipokine
Irisin/FNDC5-An updated review
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway
Irisin and FNDC5 in retrospect: an exercise hormone or a transmembrane receptor?
Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models
FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT
FNDC5: a novel player in metabolism and metabolic syndrome
Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells
Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies
New insights into the cellular activities of Fndc5/Irisin and its signaling pathways
Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure
Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to …
A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases
Increased FNDC5/Irisin expression in human hepatocellular carcinoma
Does PGC1α/FNDC5/BDNF elicit the beneficial effects of exercise on neurodegenerative disorders?
Myostatin knockout drives browning of white adipose tissue through activating the AMPK‐PGC1α‐Fndc5 pathway in muscle
FNDC5/Irisin inhibits pathological cardiac hypertrophy
Fndc5 overexpression facilitated neural differentiation of mouse embryonic stem cells
FNDC5/Irisin–their role in the nervous system and as a mediator for beneficial effects of exercise on the brain
FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity
Hepatic FNDC5 is a potential local protective factor against Non-Alcoholic Fatty Liver
Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs
FNDC5 alleviates hepatosteatosis by restoring AMPK/mTOR-mediated autophagy, fatty acid oxidation, and lipogenesis in mice
FNDC5 is produced in the stomach and associated to body composition
Irisin and FNDC5: effects of 12-week strength training, and relations to muscle phenotype and body mass composition in untrained women
FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity
A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3′ UTR
The diagnostic value of FNDC5/irisin in renal cell cancer
Progress and challenges in the biology of FNDC5 and irisin
Glucocorticoid receptor positively regulates transcription of FNDC5 in the liver
Can resistance exercise alter irisin levels and expression profiles of FNDC5 and UCP1 in rats?
FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived ‘Browning’ Factor Irisin, Determines Insulin Sensitivity
FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STAT3-associated inflammation and oxidative stress
Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations
Effects of swimming exercise on serum Irisin and bone FNDC5 in rat models of high-fat diet-induced osteoporosis
SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during …
Exercise-induced myokine FNDC5/irisin functions in cardiovascular protection and intracerebral retrieval of synaptic plasticity
Combined training, FNDC5/irisin levels and metabolic markers in obese men: A randomised controlled trial
Lack of adipocyte-fndc5/irisin expression and secretion reduces thermogenesis and enhances adipogenesis
Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes
FNDC5 promotes paclitaxel sensitivity of non-small cell lung cancers via inhibiting MDR1
Induced expression of Fndc5 significantly increased cardiomyocyte differentiation rate of mouse embryonic stem cells
Time-dependent changes in increased levels of plasma irisin and muscle PGC-1α and FNDC5 after exercise in mice
FNDC5/irisin, a molecular target for boosting reward-related learning and motivation
Greek goddess or Greek myth: the effects of exercise on irisin/FNDC5 in humans
FNDC5 attenuates oxidative stress and NLRP3 inflammasome activation in vascular smooth muscle cells via activating the AMPK-SIRT1 signal pathway
Fndc5 loss‐of‐function attenuates exercise‐induced browning of white adipose tissue in mice
Obese with higher FNDC5/Irisin levels have a better metabolic profile, lower lipopolysaccharide levels and type 2 diabetes risk
Expression of Irisin/FNDC5 in cancer cells and stromal fibroblasts of non-small cell lung cancer
Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle?
FNDC5 polymorphism influences the association between sarcopenia and liver fibrosis in adults with biopsy-proven non-alcoholic fatty liver disease
Grape pomace extract supplementation activates FNDC5/irisin in muscle and promotes white adipose browning in rats fed a high-fat diet
Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic review
FNDC5/Irisin: a new protagonist in acute brain injury
Icariin induces irisin/FNDC5 expression in C2C12 cells via the AMPK pathway
Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes
FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation
Common single nucleotide polymorphisms in the FNDC5 gene are associated with glucose metabolism but do not affect serum irisin levels in Japanese men with low …
Gene location, expression, and function of FNDC5 in Meishan pigs
A comparative study on the effects of high-fat diet and endurance training on the PGC-1α-FNDC5/irisin pathway in obese and nonobese male C57BL/6 mice
FNDC5/irisin improves the therapeutic efficacy of bone marrow-derived mesenchymal stem cells for myocardial infarction
The saturated fatty acid palmitate induces insulin resistance through Smad3-mediated down-regulation of FNDC5 in myotubes
FNDC5/Irisin attenuates diabetic cardiomyopathy in a type 2 diabetes mouse model by activation of integrin αV/β5-AKT signaling and reduction of oxidative/nitrosative …
PGC-1α–FNDC5–BDNF signaling pathway in skeletal muscle confers resilience to stress in mice subjected to chronic social defeat
Exercise training protects against aging-induced cognitive dysfunction via activation of the hippocampal PGC-1α/FNDC5/BDNF pathway
Protective actions of exercise‐related FNDC5/Irisin in memory and Alzheimer’s disease
FNDC5/Irisin System in Neuroinflammation and Neurodegenerative Diseases: Update and Novel Perspective
An Interaction between a FNDC5 Variant and Obesity Modulates Glucose Metabolism in a Chinese Han Population
… treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5 …
Associations of circulating irisin with FNDC5 expression in fat and muscle in type 1 and type 2 diabetic mice
Serum and adipose tissue mRNA levels of ATF3 and FNDC5/irisin in colorectal cancer patients with or without obesity
Upregulation of FNDC5 gene expression in C2C12 cells after single and combined treatments of resveratrol and ATRA
SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects
Skeletal muscle AMPK is essential for the maintenance of FNDC5 expression
miR-137 restricts the viability and migration of HTR-8/SVneo cells by downregulating FNDC5 in gestational diabetes mellitus
Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin …
Obesity caused by a high-fat diet regulates the Sirt1/PGC-1α/FNDC5/BDNF pathway to exacerbate isoflurane-induced postoperative cognitive dysfunction in older …
Effect of exercise training on the FNDC5/BDNF pathway in spontaneously hypertensive rats
Standardization of exercise intensity and consideration of a dose–response is essential. Commentary on “Exercise-linked FNDC5/irisin rescues synaptic …
Maternal and neonatal irisin precursor gene FNDC5 polymorphism is associated with preterm birth
Effects of dietary macronutrient composition on FNDC5 and irisin in mice skeletal muscle
Molecular identification of FNDC5 and effect of irisin on the glucose metabolism in common carp (Cyprinus carpio L.)
FNDC5 relates to skeletal muscle IGF-I and mitochondrial function and gene expression in obese men with reduced growth hormone
Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE
Circulating irisin levels and muscle FNDC5 mRNA expression are independent of IL-15 levels in mice
… study on the effects of acute and chronic downhill running vs uphill running exercise on the RNA levels of the skeletal muscles PGC1-α, FNDC5 and the adipose …
Antidepressant-like and pro-neurogenic effects of physical exercise: The putative role of FNDC5/irisin pathway
PGC-1α or FNDC5 is involved in modulating the effects of Aβ1− 42 oligomers on suppressing the expression of BDNF, a beneficial factor for inhibiting …
FNDC5 expression in Purkinje neurons of adult male rats with acute spinal cord injury following treatment with methylprednisolone
Effects of concurrent training on irisin and fibronectin type-III domain containing 5 (FNDC5) expression in visceral adipose tissue in type-2 diabetic rats
RNA/protein discordant expression of Fndc5 in central nervous system is likely to be mediated through microRNAs
Irisin-encoding gene (FNDC5) variant is associated with changes in blood pressure and lipid profile in type 2 diabetic women but not in men
Cleavage of FNDC5 and insights into its maturation process
… of irisin injections on feeding behavior and expression of appetite regulators, uncoupling proteins and lipoprotein lipase, and fasting-induced changes in FNDC5 …
Physical exercise stimulates hippocampal mTORC1 and FNDC5/irisin signaling pathway in mice: Possible implication for its antidepressant effect
Enhanced expression of FNDC5 in human embryonic stem cell-derived neural cells along with relevant embryonic neural tissues
Fndc5 knockdown induced suppression of mitochondrial integrity and significantly decreased cardiac differentiation of mouse embryonic stem cells
Curcumin improves insulin sensitivity and increases energy expenditure in high-fat-diet–induced obese mice associated with activation of FNDC5/irisin
… exercise alleviates oxidative stress-induced apoptosis in kidneys of myocardial infarction mice by inhibiting ALCAT1 and activating FNDC5/Irisin signaling pathway
NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin
Association of irisin and FNDC5 rs16835198 G> T gene polymorphism with type 2 diabetes mellitus and diabetic nephropathy. An Egyptian pilot study
The Role of FNDC5/Irisin in the Nervous System and as a Mediator for Beneficial Effects of Exercise on the Brain
Assessment of PGC1α-FNDC5 axis in granulosa cells of PCOS mouse model
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in …
Effect of sleeve gastrectomy on the expression of meteorin-like (METRNL) and Irisin (FNDC5) in muscle and brown adipose tissue and its impact on uncoupling …
The Effect of Vitamin D Supplementation on Serum and Muscle Irisin Levels, and FNDC5 Expression in Diabetic Rats
Irisin/FNDC5: A participant in camel metabolism
Characterization of fibronectin type III domain-containing protein 5 (FNDC5) gene in chickens: Cloning, tissue expression, and regulation of its expression in the …
Cardiac differentiation of mouse embryonic stem cells is influenced by a PPAR γ/PGC-1α—FNDC5 pathway during the stage of cardiac precursor cell formation
PPARγ/Pgc-1α-Fndc5 pathway up-regulation in gastrocnemius and heart muscle of exercised, branched chain amino acid diet fed mice
Impacts of rat hindlimb Fndc5/irisin overexpression on muscle and adipose tissue metabolism
Effect of Acute Resistance Training on Plasma Irisin Protein Level and Expression of Muscle FNDC5 and Adipose Tissue UCP1 Genes in Male Rats.
Obesity and its association with irisin level among individuals with FNDC5/Irisin gene variants RS16835198 and RS726344
Identification, Cloning, and Functional Analysis of the TATA-Less Mouse FNDC5 Promoter During Neural Differentiation
Impact of a single bout of high-intensity interval exercise and short-term interval training on interleukin-6, FNDC5, and METRNL mRNA expression in human …
Circular RNA AFF4 modulates osteogenic differentiation in BM-MSCs by activating SMAD1/5 pathway through miR-135a-5p/FNDC5/Irisin axis
The effectiveness of continuous and interval exercise preconditioning against chronic unpredictable stress: Involvement of hippocampal PGC-1α/FNDC5/BDNF …
FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes
FNDC5/Irisin counteracts lipotoxic-induced apoptosis in hypoxic H9c2 cells
FNDC5/irisin is expressed and regulated differently in human periodontal ligament cells, dental pulp stem cells and osteoblasts
Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and …
Auricular acupuncture induces FNDC5/irisin and attenuates obese inflammation in mice
Cardiorespiratory Fitness and Muscular Strength Moderates the Relationship between FNDC5 Polymorphism and Adiposity in Children and Adolescents
Extracellular vesicle-mediated miR135a-5p transfer in hypertensive rat contributes to vascular smooth muscle cell proliferation via targeting FNDC5
The effects of resistance and endurance training on the liver tissue FNDC5 mRNA gene expression in male rats
FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs
Role of swimming on muscle PGC-1α, FNDC5 mRNA, and assessment of serum omentin, adropin, and irisin in high carbohydrate high fat (HCHF) diet …
Increased FNDC5/IRISIN protein expression in breast cancer tissue is associated with obesity in postmenopausal women
Subchronic administration of creatine produces antidepressant-like effect by modulating hippocampal signaling pathway mediated by FNDC5/BDNF/Akt in mice
Dietary intervention, when not associated with exercise, upregulates irisin/FNDC5 while reducing visceral adiposity markers in obese rats
Music-Based Intervention Ameliorates mMecp2-Loss-Mediated Sociability Repression in Mice through the Prefrontal Cortex FNDC5/BDNF Pathway
The Acute Effects of Swimming Exercise on PGC-1α-FNDC5/Irisin-UCP1 Expression in Male C57BL/6J Mice
Ameliorative effects of garlic oil on FNDC5 and irisin sensitivity in liver of streptozotocin-induced diabetic rats
Association between FNDC5 genetic variants and proliferative diabetic retinopathy in a Chinese population
Eight Weeks of High-Intensity Interval Static Strength Training Improves Skeletal Muscle Atrophy and Motor Function in Aged Rats via the PGC-1α/FNDC5 …
Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice
ERK1/2 is a key regulator of Fndc5 and PGC1α expression during neural differentiation of mESCs
Effect of Different Exercise Mode and Ur-solic Acid Supplementation on FNDC5 and UCP1 Gene Expression and Plasma Irisin in Rats
The effects of MiR-214-3p and Irisin/FNDC5 on the biological behavior of osteosarcoma cells
miR-31-5p Promotes Oxidative Stress and Vascular Smooth Muscle Cell Migration in Spontaneously Hypertensive Rats via Inhibiting FNDC5 Expression
Fndc5 knockdown significantly decreased the expression of neurotrophins and their respective receptors during neural differentiation of mouse embryonic stem cells
Common single nucleotide polymorphisms in the FNDC5 gene and serum irisin levels in acute myocardial infarction
The data on the aerobic training with or without calorie restriction and muscular levels of Irisin and muscular FNDC5 concentration in obese male Wistar rats
FNDC5 expression closely correlates with muscle fiber types in porcine longissimus dorsi muscle and regulates myosin heavy chains (MyHCs) mRNA …
Effects of myostatin deficiency on PGC-1α and FNDC5 expression in three different murine muscle types
Effect of Training on PPARGC1A and FNDC5 Gene Expression in Thoroughbred Horses
Aerobic exercise modulates noncoding RNA network upstream of FNDC5 in the Gastrocnemius muscle of high-fat-diet-induced obese mice
Are Heart Muscle Irisin Levels and FNDC5 Gene Expression Regulated by Endurance and Resistance Exercises?
The Effect of Short Endurance Training on PGC-1α/FNDC5/BDNF Signalling Pathway In 6-OHDA-Induced Parkinson’s Rats
Associations of Circulating Irisin with FNDC5 Expression in Fat and Muscle in Type 1 and Type 2 Diabetic Mice. Biomolecules 2021, 11, 322
Diagnostic value of FNDC5 in patients with subclinical diabetic cardiomyopathy
Effect of 8 weeks resistance training on plasma irisin protein level and muscle FNDC5 and adipose tissue UCP1 genes expression in male rats
Cystathionine γ-lyase-hydrogen sulfide (H2S) deficiency downregulates muscle myokine Fndc5/Irisin and glucose metabolism in C2C12 myotubes and gastrocnemius …
Research update on the effect of irisin/FNDC5 on metabolism of children and adolescents
Evaluation of Serum Concentration of the Myokine Irisin (FNDC5) in Patients with Age-Related Macular Degeneration
Lentiviral vector overexpressing FNDC5 inhibits proliferation and migration of smooth muscle cells
Curcumin relieves CUMS-induced depressive-like behaviors through PGC-1α/FNDC5/BDNF pathway
The Effects of a High Fat Diet and Exercise on the PGC-1alpha-FNDC5/irisin Pathway in C57BL/6 Mice
Effect of Adipose Tissue-Derived Stem Cell Transplantation and Six Weeks of Aerobic Exercise on FNDC5 and Irisin Levels in Streptozotocin-Induced …
FNDC5 gene expression in the smooth muscles of dromedary camels (Camelus dromedarius).
Irisin Precursor FNDC5 and Glycemic Control in Patients With Type 2 Diabetes
Effect of muscle exercise on metabolic disturbance induced by ovariectomy alone or with diabetes mellitus in rats; targeting the role of PGC-1α and FNDC5 expression
The effect of progressive resistance and endurance training on gastrocnemius muscle’s FNDC5 gene expression in male rats
Expression of FNDC5 in liver cancer tissues and its relationship with clinical parameters
The effect of the treadmill running on genes expression ofthePGC-1α, FNDC5 and BDNF in hippocampus of male rats
The Effect of Endurance Training and High-Fat Diet on PGC-1a/FNDC5/Irisin Pathway in Male C57BL/6 Mice
Common single nucleotide polymorphisms in the FNDC5 gene and serum irisin levels in acute myocardial infarction
STUDY OF FNDC5 GENE POLYMORPHISM Rs3480 AND RS16835198 WITH OBESE PATIENTS AND SPORT INDIVIDUAL IN IRAQI POPULATIONS
Irisin and FNDC5 Responses to Exercise in Different Environmental Conditions
Expression of FNDC5/Irisin in pancreatic cancer and its relationship with clinicopathological features
miR-377 inhibition enhances the survival of trophoblast cells via upregulation of FNDC5 in gestational diabetes mellitus
FNDC5 expression in skeletal muscle in chronic heart failure: relevance of inflammatory cytokines (704.1)
Icariin Improves Lipid Metabolism via PGC1-α/FNDC5/UCP1 Pathway
MON-289 Urokinase-type Plasminogen Activator May be Linked to FNDC5 Expression during Exercise
Comparing the Effect of Aerobic Exercise with Different Intensities on FNDC5 Protein Level of Muscle Tissue in Obese Wistar Rats
… Effect of High Intensity Interval Training with Vitamin E Consumption on Serum Levels of Irisin and Gene Expression of Membrane Protein FNDC5 of Soleus Muscle in …
P-74: Effect of Fndc5 Overexpression onCardiac Differentiation Rate of mESCs
FNDC5 rs3480 A> G polymorphism disentangles steatosis from fibrosis severity in patients with nonalcoholic fatty liver disease
PO-242 Effects of tail suspension on the expression of FNDC5/Irisin protein in rat skeletal muscle
Increased FNDC5 (irisin) expression in subcutaneous adipose tissue in obese patients with type 2 diabetes 1 year after bariatric surgery
Exercise‐linked FNDC5/Irisin attenuates macrophage‐mediated renal inflammation in type 1 diabetes in aged mice
CONSTRUCTION OF A LENTI-X-ADVANCED INDUCIBLE SYSTEM CARRYING FIBRONECTIN TYPE III DOMAIN CONTAINING5 PROTEIN (FNDC5) CODING …
Different intensities of endurance training affect serum Irisin level and skeletal muscle protein expression of PGC-1alpha, FNDC5, and PPARdelta in mice with obesity …
Eight-week Climbing Ladder Exercise with Load Induces Differential Expression of PGC1α/FNDC5/MSTN in Soleus and Extensor Digitorum Longus Muscle in SD …
Assessment of The Possibility of ERK1/2 Effect on Fndc5 Expression during Neural Differentiation of Mouse Embryonic Stem Cells.
The rs1746661 polymorphism in the FNDC5 (Irisin) gene is associated with increased levels of total cholesterol in white patients with type 2 diabetes mellitus
MPS 07-03 EFFECT OF EXERCISE TRAINING ON FNDC5/BDNF PATHWAY IN THE HEART POST MYOCARDIAL INFARCTION
Construction of Recombinant Lentiviral Vector Containing shRNA against Mouse Fndc5 Gene in Order to Transduce Mouse Embryonic Stem Cells
Effects of cardiorespiratory fitness, acute aerobic exercise and common single nucleotide polymorphisms in FNDC5 gene on serum irisin levels and glucose …
THE EFFECTS OF RECOMBINANT FNDC5 PEPTIDE ADDITION TO MOUSE EMBRYONIC STEM CELL CULTURE ON EXPRESSION OF THREE GERM LAYER …
A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3’UTR Mayada Metwally, Ali …
B29 RESPIRATORY MUSCLE AT WORK: IS IT’ALL ABOUT THAT BASS’?: Expression Of The Irisin Precursor Fndc5 In Quadriceps Muscle Of COPD Patients …
Pentamethylquercetin counteracts obesity and drives brown fat-like phenotype through AMPK-mediated activation of PGC-1 alpha/FNDC5 pathway in muscle
Maternal Low Protein Diet Reduces Birth Weight And Increases Brown Adipose Tissue UCP‐1 and FNDC5 Gene Expression in Male Neonatal Sprague‐Dawley Rats
Post navigation
Previous post
Next post
Related Posts
Monkeypox
Purgatives
Neurogenesis (Growing New Brain Cells)
Mandatory FDA Disclaimer:
Not intended to diagnose, treat, cure or prevent any disease.
Mandatory FDA Disclaimer:
Not intended to diagnose, treat, cure or prevent any disease.
PRODUCTS
SCIENCE
0
0
Your Cart
Your cart is empty
Return to Shop