BECLIN-1 & AUTOPHAGY

Beclin-1 is a crucial protein for autophagy, a cellular housekeeping process that cleans out damaged organelles and proteins. This recycling system is essential for maintaining healthy cells and tissues throughout the body. Studies have shown that reduced Beclin-1 levels and impaired autophagy are linked to various age-related diseases like Alzheimerโ€™s and Parkinsonโ€™s. The theory is that malfunctioning autophagy allows harmful protein aggregates and dysfunctional organelles to accumulate, leading to cellular stress and eventually, disease. Conversely, research suggests that activating autophagy through Beclin-1 or other pathways might promote healthy aging by enhancing cellular cleaning and preventing the buildup of damage. While the exact mechanisms are still under investigation, understanding the interplay between Beclin-1, autophagy, and aging holds promise for developing future interventions to promote cellular health and longevity.


  1. A Distinct Pattern of Beclin-1 Staining Helps Distinguish Sessile Serrated Adenomas
  2. A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
  3. A novel role of Beclin-1, cytokinetic abscission
  4. A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
  5. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation
  6. A role for autophagic protein Beclin 1 early in lymphocyte development
  7. A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
  8. A179L, a new viral Bcl2 homolog targeting Beclin 1 autophagy related protein
  9. A6799 Ginsenoside Rb1 alleviate ox-LDL induced HUVEC senescence via SIRT1/Beclin-1/autophagy axis
  10. A80-C MOLECULAR AND IMMUNOBIOLOGY OF LUNG CANCER: High Levels Of Beclin-1 In Induced Sputum Of Lung Cancer Patients As A Marker Of Increased โ€ฆ
  11. Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency
  12. Aberrant Beclin 1 expression is closely linked to carcinogenesis, differentiation, progression, and prognosis of ovarian epithelial carcinoma
  13. Aberrant expression of Beclin-1 and LC3 correlates with poor prognosis of human hypopharyngeal squamous cell carcinoma
  14. Abstract C150: CaMKKฮฒ-mediated phosphorylation of Beclin 1 regulates autophagy and cell differentiation in neuroblastoma cells.
  15. Abstract P046: Hsp20 Promotes Cardiac autophagy via Interaction with Beclin-1
  16. Abstract# 1872: Mechanistic role of acetylated heat shock protein 70 in the VPS34/Beclin-1 triggered autophagy in breast cancer cells
  17. Abstract# 387: Regulation of autophagy by the Beclin 1-targeted microRNA in cancer cells
  18. Abstract# 867: Beclin 1 augments the action of a polyamine analogue in MCF-7 breast cancer cells
  19. Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth
  20. Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule Beclin-1 pathway
  21. Activation of RIG-I-mediated antiviral signaling triggers autophagy through the MAVS-TRAF6-Beclin-1 signaling axis
  22. Acute phase expression pattern of ZnTs, LC3, and Beclin-1 in rat Hippocampus and its regulation by 3-methyladenine following recurrent neonatal seizures
  23. Adiponectin inhibits inflammatory cytokines production by Beclinโ€1 phosphorylation and Bโ€cell lymphoma 2 mRNA destabilization: role for autophagy induction
  24. Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with Beclin-1 gene transfer
  25. Akt-Mediated Regulation of autophagy and Tumorigenesis Through Beclin 1
  26. Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
  27. Aldosterone Induces autophagy via an ERK-JNK/Phospho-Bcl-2/Beclin-1 Dependent Pathway in Isolated Adult Rat Ventricular Myocytes
  28. Alleviation of autophagy by knockdown of Beclin-1 enhances susceptibility of hippocampal neurons to proapoptotic signals induced by amino acid starvation
  29. All-Trans-Retinoid Acid (ATRA) Induced Upregulation of autophagy Related Proteins (LC3โ€“1, II and Beclin 1) in Acute Promyelocytic Leukemia
  30. Allyl Isothiocyanate Induces autophagy through the Up-Regulation of Beclin-1 in Human Prostate Cancer Cells
  31. Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: changes in LC3, P62, Beclin-1 and Bcl-2 levels
  32. Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension
  33. Alternative messenger RNA splicing of autophagic gene Beclin 1 in human B-cell acute lymphoblastic leukemia cells
  34. Aluminum maltolate induces primary rat astrocyte apoptosis via overactivation of the class III PI3K/Beclin 1-dependent autophagy signal
  35. AMBRA1 and Beclin 1 interplay in the crosstalk between autophagy and cell proliferation
  36. AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic myeloid โ€ฆ
  37. Amyloid-ฮฒ25โ€“35-Induced Neurotoxicity in AฮฒPP/PS1 Mice and PC12 Cells through Activation of the Class III Phosphatidylinositol 3-Kinase/Beclin-1/B-Cell Lymphoma โ€ฆ
  38. An autophagy-independent function of Beclin 1 in cancer
  39. An imbalance between Beclin-1 and p62 expression promotes the proliferation of myeloma cells through autophagy regulation
  40. An insight into the mechanistic role of Beclin 1 and its inhibition by prosurvival Bcl-2 family proteins
  41. Analysis of the role of autophagy inhibition by two complementary human cytomegalovirus BECN1/Beclin 1-binding proteins
  42. Ang II-induced Pathological autophagy is inhibited by IL-10 via Akt Dependent Inhibition of Beclin 1 in Mice Heart
  43. Antagonism of Beclin 1โ€dependent autophagy by BCLโ€2 at the endoplasmic reticulum requires NAFโ€1
  44. Anti-Apoptotic and Anti-Oxidant Proteins in Glioblastomas: Immunohistochemical Expression of Beclin and DJ-1 and Its Correlation with Prognosis
  45. Antiโ€cell death engineering of CHO cells: Coโ€overexpression of Bclโ€2 for apoptosis inhibition, Beclinโ€1 for autophagy induction
  46. Antitumor activity of rapamycin in combination with ectopic expression of Beclin 1 in multidrug-resistant cancer cells
  47. Antitumor Effects of HPV DNA Vaccine Adjuvanted with Beclin-1 as an autophagy Inducer in a Mice Model
  48. Apelin-13 impedes foam cell formation by activating Class III PI3K/Beclin-1-mediated autophagic pathway
  49. Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells
  50. Apoptosis Blocks Beclin 1-Dependent Autophagosome Synthesis
  51. Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL
  52. ARHI is required for induction of Beclin-1/PI (3) K class III-mediated autophagy
  53. Arsenic trioxide induces a Beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells
  54. Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1
  55. Artesunate protects against surgery-induced knee arthrofibrosis by activating Beclin-1-mediated autophagy via inhibition of mTOR signaling
  56. As2O3 Up-regulates the autophagy of RPMI 8226 Cells Induced by Beclin-1
  57. Aspirin induces Beclin-1-dependent autophagy of human hepatocellular carcinoma cell
  58. Association of Beclin 1 expression with response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal carcinoma
  59. Association of Beclin-1 and microRNA-30a expression with the severity and treatment response of colorectal cancer
  60. Association of elevated HIF-2ฮฑ levels with low Beclin 1 expression and poor prognosis in patients with chondrosarcoma
  61. Astemizoleโ€“Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis
  62. ATF3 PROTECT AGAINST PRESSURE OVERLOAD HEART FAILURE VIA Beclin-1 PATHWAY
  63. Atg14 and UVRAG: mutually exclusive subunits of mammalian Beclin 1-PI3K complexes
  64. Atg14L and Rubicon: yin and yang of Beclin 1-mediated autophagy control
  65. ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells
  66. attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1-mediated deacetylation of Beclin-1
  67. Author Correction: Disruption of the Beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.
  68. Author Correction: Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy
  69. Autophagic cell death induced by curcumin is mediated by p38/Beclin 1 to crosstalk with apoptotic cell death in DU145 cells
  70. Autophagic markers Beclin 1 and LC3 are associated with prognosis of multiple myeloma
  71. Autophagic protein Beclin 1 serves as an independent positive prognostic biomarker for non-small cell lung cancer
  72. Autophagic regulation of cell growth by altered expression of Beclin 1 in triple-negative breast cancer
  73. Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection
  74. autophagy and the functional roles of Atg5 and Beclin-1 in the anti-tumor effects of 3ฮฒ androstene 17ฮฑ diol neuro-steroid on malignant glioma cells
  75. autophagy biomarkers Beclin 1 and p62 are increased in cerebrospinal fluid after traumatic brain injury
  76. autophagy in Niemannโ€“Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects
  77. autophagy in pancreatic cancer cells is mediated through a non-canonical Beclin-1 independent pathway
  78. autophagy induced by suberoylanilide hydroxamic acid in Hela S3 cells involves inhibition of protein kinase B and up-regulation of Beclin 1
  79. autophagy inhibitor 3-methyladenine regulates the expression of LC3, Beclin-1 and ZnTs in rat cerebral cortex following recurrent neonatal seizures
  80. autophagy is induced by 3ฮฒ-O-succinyl-lupeol (LD9-4) in A549 cells via up-regulation of Beclin 1 and down-regulation mTOR pathway
  81. autophagy is induced in prostate cancer by 2-deoxyglucose and is Beclin-1 dependent
  82. autophagy is related to the hedgehog signaling pathway in human gastric adenocarcinoma: Prognostic significance of Beclin-1 and Gli2 expression in human gastric โ€ฆ
  83. autophagy promotes microglia activation through Beclin-1-Atg5 pathway in intracerebral hemorrhage
  84. autophagy protects PC12 cells against deoxynivalenol toxicity via the Class III PI3K/Beclin 1/Bclโ€2 pathway
  85. autophagy related markers (Beclin-1 and ATG4B) are strongly expressed in Wilmsโ€™ tumor and correlate with favorable histology
  86. autophagy, Beclin 1, and their relation to oncogenesis
  87. autophagy: kinase crosstalk through Beclin 1
  88. autophagy-active Beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas
  89. autophagy-independent enhancing effects of Beclin 1 on cytotoxicity of ovarian cancer cells mediated by proteasome inhibitors
  90. autophagy-Independent Role for Beclin 1 in the Regulation of Growth Factor Receptor Signaling: A Dissertation
  91. autophagy-inducing protein Beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infection
  92. autophagy-related gene Beclin-1 expression in neuron-like differentiation of human bone marrow mesenchymal stem cells
  93. autophagy-related protein LC3 and Beclin-1 in the first trimester of pregnancy
  94. autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer
  95. autophagy-related proteins LC3 and Beclin-1 impact the efficacy of chemoradiation on esophageal squamous cell carcinoma
  96. autophagy-related proteins, LC3 and Beclin-1, in placentas from pregnancies complicated by preeclampsia
  97. BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development
  98. Baicalein induces Beclin 1-and extracellular signal-regulated kinase-dependent autophagy in ovarian cancer cells
  99. based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1
  100. Baseline serum levels of Beclin-1, but not inflammatory factors, may predict antidepressant treatment response in Chinese Han patients with MDD: A โ€ฆ
  101. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
  102. Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function
  103. Bcl-2: Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch
  104. Bcl-xL regulates xenophagy by inhibiting the autophagosome-lysosome fusion and bacterial internalization through the Beclin 1-UVRAG complex
  105. Beclin 1 (17q21)
  106. Beclin 1 acetylation impairs the anticancer effect of aspirin in colorectal cancer cells
  107. Beclin 1 activation enhances chemosensitivity and predicts a favorable outcome for primary duodenal adenocarcinoma
  108. Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
  109. Beclin 1 and bcl-2 expressions in bladder urothelial tumors and their association with clinicopathological parameters
  110. Beclin 1 and its emerging role as a prognostic biomarker in systemic malignancies besides bladder carcinomas
  111. Beclin 1 and LC3 as predictive biomarkers for metastatic colorectal carcinoma
  112. Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions
  113. Beclin 1 and nuclear factor-ฮบBp65 are upregulated in hepatocellular carcinoma
  114. Beclin 1 and p62 expression in non-small cell lung cancer: relation with malignant behaviors and clinical outcome
  115. Beclin 1 and UVRAG confer protection from radiation-induced DNA damage and maintain centrosome stability in colorectal cancer cells
  116. Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity
  117. Beclin 1 biology and its role in heart disease
  118. Beclin 1 bridges autophagy, apoptosis and differentiation
  119. Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
  120. Beclin 1 complex in autophagy and Alzheimer disease
  121. Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
  122. Beclin 1 deficiency causes hepatic cell apoptosis via endoplasmic reticulum stress in zebrafish larvae
  123. Beclin 1 deficiency correlated with lymph node metastasis, predicts a distinct outcome in intrahepatic and extrahepatic cholangiocarcinoma
  124. Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis
  125. Beclin 1 enhances proteasome inhibition-mediated cytotoxicity of thyroid cancer cells in macroautophagy-independent manner
  126. Beclin 1 expression in ovarian tissues and its effects on ovarian cancer prognosis
  127. Beclin 1 expression is an independent prognostic factor for gastric carcinomas
  128. Beclin 1 expression is associated with the occurrence and development of esophageal squamous cell carcinoma
  129. Beclin 1 expression is closely linked to colorectal carcinogenesis and distant metastasis of colorectal carcinoma
  130. Beclin 1 expression predicts favorable clinical outcome in patients with diffuse large B-cell lymphoma treated with R-CHOP
  131. Beclin 1 expression: a predictor of prognosis in patients with extranodal natural killer T-cell lymphoma, nasal type
  132. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
  133. Beclin 1 gene inhibits tumor growth in colon cancer cell lines
  134. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in ฮฑ-synuclein models of Parkinsonโ€™s and Lewy body diseases
  135. Beclin 1 influences cisplatin-induced apoptosis in cervical cancer CaSki cells by mitochondrial dependent pathway
  136. Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process
  137. Beclin 1 Interacts With Active Caspase-3 and Bax in Oocytes From Atretic Follicles in the Rat Ovary
  138. Beclin 1 is dispensable for chromosome congression and proper outer kinetochore assembly
  139. Beclin 1 is highly expressed in papillary thyroid carcinoma and correlates with lymph node metastasis
  140. Beclin 1 is involved in regulation of apoptosis and autophagy during replication of ectromelia virus in permissive L929 cells
  141. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex
  142. Beclin 1 is required for starvation-enhanced, but not rapamycin-enhanced, LC3-associated phagocytosis of Burkholderia pseudomallei in RAW 264.7 cells
  143. Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral โ€ฆ
  144. Beclin 1 knockdown retards re-endothelialization and exacerbates neointimal formation via a crosstalk between autophagy and apoptosis
  145. Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machadoโ€“Joseph disease
  146. Beclin 1 modulates the anti-apoptotic activity of Bcl-2: insights from a pathogen infection system
  147. Beclin 1 mRNA Strongly Correlates with Bcl-XLmRNA Expression in Human Hepatocellular Carcinoma
  148. Beclin 1 or not Beclin 1โ€ฆ
  149. Beclin 1 over-and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia
  150. Beclin 1 overexpression inhibits chondrocyte apoptosis and downregulates extracellular matrix metabolism in osteoarthritis
  151. Beclin 1 phosphorylationโ€“at the centre of autophagy regulation
  152. Beclin 1 promotes apoptosis and decreases invasion by upregulating the expression of ECRG4 in A549 human lung adenocarcinoma cells
  153. Beclin 1 promotes endosome recruitment of hepatocyte growth factor tyrosine kinase substrate (HRS) to suppress tumor proliferation
  154. Beclin 1 regulates growth factor receptor signaling in breast cancer
  155. Beclin 1 regulates neuronal transforming growth factor-ฮฒ signaling by mediating recycling of the type I receptor ALK5
  156. Beclin 1 regulates recycling endosome and is required for skin development in mice
  157. Beclin 1 Regulates Smoke Induced Kidney Injury in a Murine Model of Chronic Obstructive Pulmonary Disease
  158. Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner
  159. Beclin 1 selfโ€association is independent of autophagy induction by amino acid deprivation and rapamycin treatment
  160. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
  161. Beclin 1, an autophagy-related gene, augments apoptosis in U87 glioblastoma cells
  162. Beclin 1, an essential component and master regulator of PI3K-III in health and disease
  163. Beclin 1, Bcl-2 and autophagy
  164. Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis
  165. Beclin 1: a BH3-only protein that fails to induce apoptosis
  166. Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
  167. Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound, Z18
  168. Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death
  169. Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling
  170. Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells
  171. Beclin 1-Vps34 complex architecture: Understanding the nuts and bolts of therapeutic targets
  172. Beclin-1 and autophagy: potential for new therapeutics in neurodegeneration
  173. Beclin-1 and hypoxia-inducible factor-1ฮฑ genes expression: potential biomarkers in acute leukemia patients
  174. Beclin-1 and LC3A expression in cutaneous malignant melanomas: a biphasic survival pattern for Beclin-1
  175. Beclin-1 as a neutrophil-specific immune checkpoint
  176. Beclin-1 circulating levels in middle-aged men with sleep-disordered breathing
  177. Beclin-1 deficiency alters autophagosome formation, lysosome biogenesis and enhances neuronal vulnerability of HT22 hippocampal cells
  178. Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor
  179. Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNKmediated autophagic cell death
  180. Beclin-1 expression in normal bladder and in Cd2+ and As3+ exposed and transformed human urothelial cells (UROtsa)
  181. Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1ฮฑ โ€ฆ
  182. Beclin-1 expression is a significant predictor of survival in patients with lymph node-positive gastric cancer
  183. Beclin-1 expression is retained in high-grade serous ovarian cancer yet is not essential for autophagy induction in vitro
  184. Beclin-1 Haploinsufficiency Protects Against Obesity-induced Cardiac Dysfunction Through Compensatory Mitophagy and Alternative autophagy
  185. Beclin-1 is involved in the regulation of antimicrobial peptides expression in Chinese mitten crab Eriocheir sinensis
  186. Beclin-1 is involved in tongue sole Cynoglossus semilaevis immune defense against bacterial infection
  187. Beclinโ€1 is required for chromosome congression and proper outer kinetochore assembly
  188. Beclinโ€1 is required for RANKLโ€induced osteoclast differentiation
  189. Beclin-1 is required for T cell-mediated immune responses (143.19)
  190. Beclin-1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK-ES-1 cells via inhibition of MMP-9
  191. Beclin-1 knockdown shows abscission failure but not autophagy defect during oocyte meiotic maturation
  192. Beclin-1 regulates cigarette smokeโ€“induced kidney injury in a murine model of chronic obstructive pulmonary disease
  193. Beclin-1 regulation of autophagy in endocrine resistant breast cancer
  194. Beclinโ€‘1 suppresses gastric cancer progression by promoting apoptosis and reducing cell migration
  195. Beclin-1 targeting for viral immune escape
  196. Beclin-1: autophagic regulator and therapeutic target in cancer
  197. Beclin-1-dependent autophagy protects the heart during sepsis
  198. Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat โ€ฆ
  199. Beclin-1-independent autophagy positively regulates internal ribosomal entry site-dependent translation of hypoxia-inducible factor 1ฮฑ under nutrient โ€ฆ
  200. Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking
  201. Beclin-1-mediated autophagy may be involved in the elderly cognitive and affective disorders in streptozotocin-induced diabetic mice
  202. Beclin-1-mediated autophagy protects against cadmium-activated apoptosis via the Fas/FasL pathway in primary rat proximal tubular cell culture
  203. Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis
  204. Beclinโ€1โ€“p53 interaction is crucial for cell fate determination in embryonal carcinoma cells
  205. BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid ฮฒ 42
  206. BECN1/Beclin 1 sorts cell-surface APP/amyloid ฮฒ precursor protein for lysosomal degradation
  207. Beta-asarone attenuates ischemiaโ€“reperfusion-induced autophagy in rat brains via modulating JNK, p-JNK, Bcl-2 and Beclin 1
  208. Beta-Asarone Reduces autophagy in a Dose-Dependent Manner and Interferes with Beclin 1 Function
  209. BH3-Only Proteins and BH3 Mimetics Induce autophagy by Competitively Disrupting the Interaction between Beclin 1 and Bcl-2/Bcl-XL
  210. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
  211. Bim inhibits autophagy by recruiting Beclin 1 to microtubules
  212. Biochemical and Genetic Studies of Beclin 1 Function in autophagy
  213. Bone marrow mesenchymal stem cells protect against n-hexane-induced neuropathy through Beclin 1-independent inhibition of autophagy
  214. Cadmiumโ€‘induced autophagy promotes survival of rat cerebral cortical neurons by activating class III phosphoinositide 3โ€‘kinase/beclinโ€‘1/Bโ€‘cell lymphoma 2 โ€ฆ
  215. Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo
  216. CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation
  217. cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
  218. Can enhanced autophagy be associated with human longevity? Serum levels of the autophagy biomarker Beclin-1 are increased in healthy centenarians
  219. Carbon monoxide confers protection in sepsis by enhancing Beclin 1-dependent autophagy and phagocytosis
  220. Caspase 1 activation is protective against hepatocyte cell death by up-regulating Beclin 1 protein and mitochondrial autophagy in the setting of redox stress
  221. Caspase mediated beclinโ€1 dependent autophagy tuning activity and apoptosis promotion by surface modified hausmannite nanoparticle
  222. Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells
  223. Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors โ€ฆ
  224. CCAAT-Enhancer-binding protein homologous protein promotes liver ischemia and reperfusion injury by inhibiting Beclin-1-mediated autophagy in hepatocytes
  225. CCCP-Induced LC3 lipidation depends on Atg9 whereas FIP200/Atg13 and Beclin 1/Atg14 are dispensable
  226. Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of Beclin 1
  227. Change of Beclinโ€1 dependent on ATP, [Ca2+]i and MMP in PC12 cells following oxygenโ€glucose deprivationโ€reoxygenation injury
  228. Changes in Beclin-1 and micro-calpain expression in tri-ortho-cresyl phosphate-induced delayed neuropathy
  229. Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons
  230. Changes in expression of autophagy-related proteins, Beclin-1 and LC3, and effects of rapamycin on their expression in hypoxic-ischemic hippocampus
  231. Changes of Beclin 1 expression in radiation-induced autophagy in breast cancer cells
  232. Characterisation of the conformational preference and dynamics of the intrinsically disordered N-terminal region of Beclin 1 by NMR spectroscopy
  233. Characterization of apoptosis and autophagy through Bcl-2 and Beclin-1 immunoexpression in gestational trophoblastic disease
  234. Characterization of the Full-Length, Human Beclin-1 Purified from Escherichia Coli
  235. Chemoresistance is associated with Beclin-1 and PTEN expression in epithelial ovarian cancers
  236. CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2
  237. Chromosome band 17q21 in breast cancer: Significant association between Beclin 1 loss and HER2/NEU amplification
  238. CISD2 promotes the proliferation of glioma cells via suppressing beclinโ€‘1โ€‘mediated autophagy and is targeted by microRNAโ€‘449a
  239. Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis
  240. Clinical significance of Beclin-1, Bcl-2, Bcl-xL, Bad and Bax in the whole spectrum of HCV-related chronic liver diseases
  241. Clinical significance of the expression of autophagy-associated marker, Beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy
  242. Clinical value of CagA, cโ€‘Met, PI3K and Beclinโ€‘1 expressed in gastric cancer and their association with prognosis
  243. Clinicopathologic correlation of autophagy-related Beclin-1 expression in gallbladder cancer.
  244. Clinicopathologic correlation of Beclin-1 and bcl-2 expression in human breast cancer
  245. Clinicopathologic correlation of Beclin-1 expression in pancreatic ductal adenocarcinoma
  246. Clinicopathologic correlations between human papillomavirus 16 infection and Beclin 1 expression in human cervical cancer
  247. Clinicopathological correlation of Beclin-1 expression in human colon cancer.
  248. Clinicopathological correlations of autophagy-related proteins LC3, Beclin 1 and p62 in gastric cancer
  249. Cloning and genomic organization of Beclin 1, a candidate tumor suppressor gene on chromosome 17q21
  250. Cloning of the autophagy-related gene Beclin-1 of the marine teleost Paralichthys olivaceus and its possible implication in viral replication
  251. Closed head injury induces upregulation of Beclin 1 at the cortical site of injury
  252. Cocaine-mediated autophagy in astrocytes involves sigma 1 receptor, PI3K, mTOR, Atg5/7, Beclin-1 and induces type II programed cell death
  253. Combing oncolytic adenovirus expressing Beclin-1 with chemotherapy agent doxorubicin synergistically enhances cytotoxicity in human CML cells in vitro
  254. Common and divergent functions of Beclin 1 and Beclin 2
  255. Comparative immunohistochemical analysis of Beclin-1 & MDM-2 in benign & malignant ameloblastomas
  256. Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/Beclin-1 in breast cancer cells
  257. Construction of shRNA expression vectors for autophagy gene Beclin 1 and effect of the vectors on transfected HeLa cells in vitro
  258. Construction of shRNA expression vectors for autophagy gene Beclin 1 and their downregulation effect on caspase-9
  259. Construction of shRNA Expression Vectors for autophagy Gene Beclin 1 and Their Downregulation Effect on Caspase-9 [J]
  260. Correction for Chaumorcel et al.,โ€œThe Human Cytomegalovirus Protein TRS1 Inhibits autophagy via Its Interaction with Beclin 1โ€
  261. Correction to: miR-762 modulates thyroxine-induced cardiomyocyte hypertrophy by inhibiting Beclin-1
  262. Correction: Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-ฮบB
  263. Correction: The viral restriction factor Tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with Beclin 1 and B-cell โ€ฆ
  264. Correlation Analysis on autophagy Gene Beclin 1 to Tumorigenes, Development and Prognosis of Bladder Transitional Cell Carcinoma
  265. Coxiella burnetii modulates Beclin 1 and Bcl-2, preventing host cell apoptosis to generate a persistent bacterial infection
  266. Critical role of autophagy proteins Beclin 1 and LC3B in deguelin-induced apoptosis in pancreatic tumor cells in vitro and in vivo: A new paradigm
  267. Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
  268. Crosstalk between apoptosis and autophagy is regulated by the arginylated BiP/Beclin-1/p62 complex
  269. Crosstalk between apoptosis and autophagy within the Beclin 1 interactome
  270. Crosstalk between Beclin-1-dependent autophagy and caspaseโ€‘dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells
  271. Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses
  272. Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
  273. Crystal structure of the Bcl-XL-Beclin 1 peptide complex Beclin 1 is a novel BH3-only protein
  274. Cyclin D1 Co-localizes with Beclin-1 in Glioblastoma Recurrences: A Clue to a Therapy-induced, autophagy-mediated Degradative Mechanism?
  275. Cytotoxic effects of a sesquiterpene ฮฒ-elemene on THP-1 leukemia cells is mediated via crosstalk between Beclin-1 mediated autophagy and caspase-dependent โ€ฆ
  276. DAPโ€kinaseโ€mediated phosphorylation on the BH3 domain of Beclin 1 promotes dissociation of Beclin 1 from Bclโ€XL and induction of autophagy
  277. Decorin-inducible Peg3 evokes Beclin 1-mediated autophagy and thrombospondin 1-mediated angiostasis
  278. Decreased Beclin-1 expression is correlated with the growth of the primary tumor in patients with squamous cell carcinoma and adenocarcinoma of the lung
  279. Decreased expression of autophagic Beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts
  280. Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma
  281. Decreased expression of Beclin 1 correlates with a metastatic phenotypic feature and adverse prognosis of gastric carcinomas
  282. Decreased expression of Beclin 1 in eutopic endometrium of women with adenomyosis
  283. Decreased expression of Beclin-1 and LC3 in human lung cancer
  284. Decreased expression of Beclin-1 in patients with hepatocellular carcinoma.
  285. Decreased expression of Beclinโ€‘1 is significantly associated with a poor prognosis in oral tongue squamous cell carcinoma
  286. Decreased miR-124-3p Expression Prompted Breast Cancer Cell Progression Mainly by Targeting Beclin-1.
  287. Defective Beclin-1 and elevated hypoxia-inducible factor (HIF)-1ฮฑ expression are closely linked to tumorigenesis, differentiation, and progression of hepatocellular โ€ฆ
  288. dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway
  289. Delayed cardioprotection by sevoflurane preconditioning: a novel mechanism via inhibiting Beclin 1-mediated autophagic cell death in cardiac myocytes โ€ฆ
  290. Dendrimerโ€mediated siRNA delivery knocks down Beclin 1 and potentiates NMDAโ€mediated toxicity in rat cortical neurons
  291. Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimerโ€™s disease brain
  292. Deregulation of Beclin 1 in patients with tobacco-related oral squamous cell carcinoma
  293. Diagnostic Significance of Beclin-1 and Transforming Growth Factor ฮฒ in Breast Cancer
  294. Dietary Nitrate Supplementation With Beetroot Juice Enhances Cardiac autophagy Markers AMBRA-1 (Activating Molecule in Beclin-1-regulated autophagy) and ATG โ€ฆ
  295. Diethylstilbestrol (DES) induces autophagy in thymocytes by regulating Beclin-1 expression through epigenetic modulation
  296. Differential changes of BNIP3 and Beclin-1 during the right ventricle response to sustained or intermittent hypoxia
  297. Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells
  298. Differential Expression of autophagy-Related Marker (Beclin-1) in Relation to Clinicopathological Parameters in Different Breast Cancer Molecular Subtypes
  299. Differential interactions between Beclin 1 and Bcl-2 family members
  300. Direct molecular interactions between Beclin 1 and the canonical NFฮบB activation pathway
  301. directly, by inhibiting fusion between autophagosomes and lysosomes, and indirectly, by inhibiting bacterial internalization via interaction with Beclin 1 โ€ฆ
  302. Disruption of the Beclin 1โ€“BCL2 autophagy regulatory complex promotes longevity in mice
  303. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1โ€“phosphatidylinositol-3-kinase complex
  304. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
  305. Does Beclin-1 have a role in hepatocellular carcinoma in Egyptian patients?
  306. Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy
  307. Down-regulation of miRNA-30a alleviates cerebral ischemic injury through enhancing Beclin 1-mediated autophagy
  308. Dual effects of 1, 15-bis (ethylamino) 4, 8, 12-triazapentadecane (BE-3-3-3-3) on MCF-7 cells in the presence and absence of estradiol: Role of Beclin 1 and โ€ฆ
  309. Dynamic expressions of Beclin 1 and tyrosine hydroxylase in different areas of 6-hydroxydopamine-induced Parkinsonian rats
  310. EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62-mediated lysosomal degradation of c-Myc
  311. Effect and mechanism of an autophagy gene Beclin 1 on cervical cancer HeLa cells
  312. Effect of autophagy gene Beclin 1 on the growth of cervical cancer HeLa cells in vitro and vivo
  313. Effect of baicalin on the autophagy and Beclin-1 expression in rats with cerebral ischemia
  314. Effect of Beclin 1 expression on the biological behavior and chemotherapy sensitivity of cervical cancer cells
  315. Effect of Beclin 1 RNA interference on Vit K_3 injured SMMC-7721 cells [J]
  316. Effect of Beclin-1 shRNA on hypoxia-induced autophagy in SH-SY5Y cells
  317. Effect of Bufei decoction on autophagy-related proteins Cat-D, Beclin-1, and p62 involved in pulmonary fibrosis
  318. Effect of Electroacupuncture and Moxibustion Pretreatment on Expression of autophagy Related Proteins LC 3 and Beclin 1 in Rats with Myocardial Ischemia โ€ฆ
  319. Effect of electroacupuncture serum on expression of myogenic differentiation antigen and autophagy-related protein Beclin 1 in cultured muscle satellite cells under โ€ฆ
  320. Effect of electroacupuncture with different frequencies on hindlimb locomotor function and expression of LC3, Beclin 1 and cleaved Caspase-3 proteins in spinal cord โ€ฆ
  321. Effect of inhibiting Beclin-1 expression on autophagy, proliferation and apoptosis in colorectal cancer
  322. Effect of Moxibustion Preconditioning with Seed-sized Moxa Cones on Myocardial Infarction Size and Beclin 1 Expression in Myocardial Ischemia-reperfusion Injury โ€ฆ
  323. Effects of Beclin 1 overexpression on aggressive phenotypes of colon cancer cells
  324. Effects of E-64d on Expression of Beclin-1 Protein in Cerebral Cortex of Developmental Seizures Rats [J]
  325. Effects of high-mobility group box 1 on the expression of Beclin-1 and LC3 proteins following hypoxia and reoxygenation injury in rat cardiomyocytes
  326. Effects of Ischemic Post-Conditioning on the Expressions of LC3-II and Beclin-1 in the Hippocampus of Rats after Cerebral Ischemia and Reperfusion
  327. Effects of miR-26a on the expression of Beclin 1 in retinoblastoma cells
  328. Effects of NF-ฮบB p65 siRNA on the apoptosis of hepatoma cell line SM-7721 and expression of Bcl-2, Atg5, Beclin-1 genes [J]
  329. Effects of Simulated Weightlessness on Expression of Beclin-1 and LC3 in the Ventricular Muscle of Rats
  330. EGb761 improves the cognitive function of elderly db/dbโˆ’/โˆ’ diabetic mice by regulating the Beclin-1 and NF-ฮบB signaling pathways
  331. EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
  332. Egr-1 is involved in coronary microembolization-induced myocardial injury via Bim/Beclin-1 pathway-mediated autophagy inhibition and apoptosis activation
  333. Elemene Increases Autophagic Apoptosis and Drug Sensitivity in Human Cisplatin (DDP)-Resistant Lung Cancer Cell Line SPC-A-1/DDP By Inducing Beclin-1 โ€ฆ
  334. Elevated Beclin 1 expression is correlated with HIF-1ฮฑ in predicting poor prognosis of nasopharyngeal carcinoma
  335. Emerging protective roles of shengmai injection in septic cardiomyopathy in mice by inducing myocardial mitochondrial autophagy via caspase-3/Beclin-1 axis
  336. Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and ฮฒโ€catenin levels
  337. Endothelial cell autophagy in chronic intermittent hypoxia is impaired by miRNAโ€30aโ€mediated translational control of Beclinโ€1
  338. Enhancement of hepatitis E virus DNA vaccine immunity by Beclin-1-mediated autophagy
  339. Epidermal autophagy and Beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I โ€ฆ
  340. Erratum to: Sinha S, Colbert CL, Becker N, Wei Y, Levine B. Molecular basis of the regulation of Beclin 1-dependent autophagy by the ฮณ-herpesvirus 68 Bcl-2 homolog โ€ฆ
  341. ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases
  342. Establish a flow cytometric method for quantitative detection of Beclin-1 expression
  343. Evaluation of Beclin 1 and Atg10 gene expression of the autophagy pathway in acute lymphoblastic leukemia patient
  344. Evaluation of Beclin-1 and Atg5 genes expression levels in peripheral blood cells of patients with rheumatoid arthritis
  345. Evaluation of protein levels of autophagy markers (Beclin 1 and SQSTM1/p62) and phosphorylation of cyclin E in the placenta of women with preeclampsia.
  346. Expression analysis of the Beclin-1 in premalignant and malignant tissues of the uterine cervix
  347. Expression and clinical significance of autophagy gene Beclin 1 in cervical squamous cell carcinoma
  348. Expression and clinical significance of autophagy-related gene Beclin 1 in astrocytic tumors
  349. Expression and clinical significance of autophagy-related gene Beclin 1 in epithelial ovarian cancer
  350. Expression and clinical significance of autophagy-related genes LC3, Beclin-1 and apoptosis-related genes p53, BCL-2 in colorectal carcinoma [J]
  351. Expression and clinical significance of Beclin-1 in childhood acute lymphoblastic leukemia [J]
  352. Expression and clinical significance of Beclinโ€‘1 in gastric cancer tissues of various clinical stages
  353. Expression and Clinical Significance of Beclin-1 in Hodgkin Lymphoma
  354. Expression and clinical significance of Beclin-1, Bcl-2, and Bax in renal cells of rats with exprimental fluorosis
  355. Expression and clinical significance of the autophagy proteins Beclin 1 and LC3 in ovarian cancer
  356. Expression and involved signal transduction pathway of autophagy gene Beclin 1 in epithelial ovarian cancer
  357. Expression and significance of Beclin 1 and LC3 in parotid pleomorphic adenoma and carcinoma in pleomorphic adenoma [J]
  358. EXPRESSION AND SIGNIFICANCE OF Beclin 1 IN RECURRENT PLEOMORPHIC ADENOMA OF PAROTID
  359. Expression and Significance of Beclin-1 and Bcl-2 in Gastric Cancer
  360. Expression and significance of Beclin-1 in vasculogenic mimicry formation of gastric cancer
  361. Expression of autophagy gene Beclin 1 in cervical squamous cell carcinoma and its relationship with infection of HPV16
  362. Expression of autophagy Markers Beclin-1 and LC3 in Cervical Cancer
  363. Expression of autophagy related gene Beclin-1 and number of autophagic vacuoles in bone marrow mononuclear cells from 40 myelodysplastic syndromes patients โ€ฆ
  364. Expression of autophagy-associated protein Beclin 1 in the hippocampus after global brain ischemia-reperfusion injury in rats
  365. Expression of autophagyโ€related markers beclinโ€1, light chain 3A, light chain 3B and p62 according to the molecular subtype of breast cancer
  366. Expression of autophagy-related protein Beclin-1 and microtubule-associated protein 2 light chain 3 in periodontal ligament cells in orthodontic tooth pressure areas
  367. Expression of autophagy-related protein Beclin-1 in malignant canine mammary tumors
  368. Expression of Beclin 1 and Bclโ€‘2 in pancreatic neoplasms and its effect on pancreatic ductal adenocarcinoma prognosis
  369. Expression of Beclin 1 and LC3 in FIGO stage Iโ€“II cervical squamous cell carcinoma and relationship to survival
  370. Expression of Beclin 1 in bladder cancer and its clinical significance
  371. Expression of Beclin 1 in nonโ€small cell lung cancer: an immunohistochemical study
  372. Expression of Beclin 1 in primary salivary adenoid cystic carcinoma and its relation to Bcl-2 and p53 and prognosis
  373. Expression of Beclin 1, an autophagy-related protein, in human cervical carcinoma and its clinical significance.
  374. Expression of Beclin-1 and LAMP-2 in Rat Hippocampus under Conditions of Simulated Gravity Overload in the Caudocranial Vector
  375. Expression of Beclin-1 as a Marker for autophagy and Its Predictive and Prognostic Performance in Patients with Metastatic Colon Cancer
  376. Expression of Beclin-1 in non-small cell lung cancer and its clinical significance
  377. Expression of Beclin-1 in the microenvironment of invasive ductal carcinoma of the breast: correlation with prognosis and the cancer-stromal interaction
  378. Expression of Beclinโ€1, an autophagyโ€related marker, in chronic hepatitis and hepatocellular carcinoma and its relation with apoptotic markers
  379. Expression of beclinโ€1, an autophagyโ€related protein, in gastric and colorectal cancers
  380. Expression of cFLIPL Determines the Basal Interaction of Bclโ€2 With Beclinโ€1 and Regulates p53 Dependent Ubiquitination of Beclinโ€1 During Autophagic Stress
  381. Expression of c-Myc and Beclin-1 in skin of rats after burn
  382. Expression of glucose transporter-1, hypoxia inducible factor-1ฮฑ and Beclin-1 in head and neck cancer and their implication
  383. Expression of LC3 and Beclin 1 in the spinal dorsal horn following spinal nerve ligation-induced neuropathic pain
  384. Expression of the Bcl-2 binding protein Beclin 1 in human idiopathic pulmonary fibrosis
  385. Expression, modulation, and clinical correlates of the autophagy protein Beclinโ€1 in esophageal adenocarcinoma
  386. Expressions of Beclin-1 and LC3 in rats with hypoxic pulmonary hypertension
  387. Fasudil, a Rho kinase inhibitor, promotes the autophagic degradation of A53T ฮฑ-synuclein by activating the JNK 1/Bcl-2/Beclin 1 pathway
  388. Ferroferric oxide nanoparticles induce prosurvival autophagy in human blood cells by modulating the Beclin 1/Bcl-2/VPS34 complex
  389. Fluorouracil induces autophagy-related gastric carcinoma cell death through Beclin-1 upregulation by miR-30 suppression
  390. Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death
  391. Following Cytochrome c Release, autophagy Is Inhibited during Chemotherapy-Induced Apoptosis by Caspase 8โ€“Mediated Cleavage of Beclin 1
  392. Forced expression of MIR-30A-5P sensitizes bladder cancer cells to cisplatin via targeting ATG5 and Beclin-1
  393. FOXM1 plays a role in autophagy by transcriptionally regulating Beclin-1 and LC3 genes in human triple-negative breast cancer cells
  394. FRI0512 RETRO-INVERSO TAT-Beclin-1 INDUCES SYNOVIAL FIBROSIS AND DOES NOT PROTECT CARTILAGE FROM DEGENERATION IN A MOUSE MODEL โ€ฆ
  395. From a global view to focused examination: understanding cellular function of lipid kinase VPS34-Beclin 1 complex in autophagy
  396. Full anti-apoptotic function of Bcl-XL complexed with Beclin-1 verified by live-cell FRET assays
  397. Functional Analysis of the Beclin-1 Tumor Suppressor Interaction With hVps34 (Type-III P13-Kinase) in Breast Cancer Cells
  398. Functional and physical interaction between Bclโ€XL and a BH3โ€like domain in Beclinโ€1
  399. Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll-like receptor-mediated autophagy
  400. Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma
  401. Genetic and epigenetic silencing of the Beclin 1 gene in sporadic breast tumors
  402. Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis.
  403. Ginsenoside Rg1 protects against sepsis-associated encephalopathy through Beclin 1โ€“independent autophagy in mice
  404. Glucagon-Like Peptide-1 Receptor Agonist Attenuates autophagy to Ameliorate Pulmonary Arterial Hypertension through Drp1/NOX-and Atg-5/Atg-7/Beclin-1/LC3ฮฒ โ€ฆ
  405. GP-1 induces autophagy of human colorectal cancer cells by inhibiting AKT/mTOR and activating type III PI3K/Beclin 1 signaling pathways
  406. Grape Seed Proanthocyanidin Extract Down-Regulates Autophagic Proteins (LC3II and Beclin-1) in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury
  407. GW27-e1027 MiR-129-5p-mediated Beclin-1 suppression inhibits endothelial cell autophagy in atherosclerosis
  408. HAb18G/CD147 inhibits starvationโ€induced autophagy in human hepatoma cell SMMC7721 with an involvement of Beclin 1 downโ€regulation
  409. Hepatitis B virus X protein sensitizes cells to starvationโ€induced autophagy via upโ€regulation of Beclin 1 expression
  410. Hepatitis C virus nonstructural 5A protein inhibits the starvationโ€‘induced apoptosis of hepatoblastoma cells by increasing Beclin 1 expression
  411. Heterozygous Disruption of Beclin 1 Alleviates Zinc Oxide Nanoparticles-Induced Disturbance of Cholesterol Biosynthesis in Mouse Liver
  412. High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas
  413. High Beclin-1 and ARID1A expression corelates with poor survival and high recurrence in intrahepatic cholangiocarcinoma: a histopathological retrospective โ€ฆ
  414. High Beclin-1 Expression in Human Alveolar Macrophage Significantly Correlate with the Bacteriologic Sterilization in Pulmonary Tuberculosis Patients.
  415. High expression of Beclin-1 predicts favorable prognosis for patients with colorectal cancer
  416. High expression of the autophagy gene Beclinโ€1 is associated with favorable prognosis for salivary gland adenoid cystic carcinoma
  417. High Levels Of Beclin-1 In Induced Sputum Of Lung Cancer Patients As A Marker Of Increased autophagy
  418. Higher expression of Beclin 1 in human meningiomas is related to better clinical outcome and pathological grade
  419. High-throughput screens to identify autophagy inducers that function by disrupting Beclin 1/Bcl-2 binding
  420. Histone deacetylase 6 functions as a tumor suppressor by activating cโ€Jun NH2โ€terminal kinaseโ€mediated Beclin 1โ€dependent autophagic cell death in liver cancer
  421. HIV Tat and Morphine-induced Neurodegeneration in a Beclin 1 Hemizygous Mouse Model
  422. HMGB1: a novel Beclin 1-binding protein active in autophagy
  423. HSV-1 ICP34. 5 confers neurovirulence by targeting the Beclin 1 autophagy protein
  424. Hydrogen peroxide induces Beclin 1-independent autophagic cell death by suppressing the mTOR pathway via promoting the ubiquitination and degradation of Rheb โ€ฆ
  425. Hypoxia induces Beclin-1 expression and autophagic cell death in apoptosis-competent cells
  426. Hypoxia-induced downregulation of autophagy mediator Beclin-1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis
  427. Identification and characterization of Beclin 1 interacting proteins and Beclin 1 post-translational modifications
  428. Identification of Autophagic Protein Beclin 1 as a K-RBP Interacting Protein
  429. Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
  430. Identification of Beclin-1 from orange-spotted grouper (Epinephelus coioides) involved in viral infection
  431. Identification of novel small molecule Beclin 1 mimetics activating autophagy
  432. IKKฮฒ/NFฮบBp65 activated by interleukin-13 targets the autophagy-related genes LC3B and Beclin 1 in fibroblasts co-cultured with breast cancer cells
  433. Imatinib induces autophagy through BECLINโ€1 and ATG5 genes in chronic myeloid leukemia cells
  434. Immunohistochemical expressions of SQSTM1/p62, Beclin-1, and SOX4 in infiltrating duct carcinoma of the breast
  435. Immunolocalization of Beclin 1, a bcl-2-binding, autophagy-related protein, in the human ovary: possible relation to life span of corpus luteum
  436. Immunopositivity of Beclin-1 and ATG5 as indicators of survival and disease recurrence in oral squamous cell carcinoma
  437. Impact of Targeting the autophagy Related Gene Beclin 1 on the Immune Landscape of Melanoma
  438. Impaired autophagy and APP processing in Alzheimerโ€™s disease: the potential role of Beclin 1 interactome
  439. Inactivation of Beclinโ€1โ€dependent autophagy promotes ursolic acidโ€induced apoptosis in hypertrophic scar fibroblasts
  440. INAUGURAL ARTICLE by a Recently Elected Academy Member: Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory โ€ฆ
  441. induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-ฮบB, Beclin-1, p62 and NBR1) โ€ฆ
  442. Induction of autophagy and inhibition of tumorigenesis by Beclin 1
  443. Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage
  444. Induction of autophagy with Beclin-1 is not Sufficient to Reduce Atherosclerosis
  445. Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells
  446. Inflachromene inhibits autophagy through modulation of Beclin 1 activity
  447. INHIBITION OF autophagy GENE Beclin 1 EXPRESSION ON SENSITIVITY OF OVARIAN CANCER CELLS A2780/DDP TO CISPLATIN AND ITS MECHANISM
  448. Inhibition of autophagy promotes cisplatin-induced apoptotic cell death through Atg5 and Beclin 1 in A549 human lung cancer cells
  449. Inhibition of Beclin 1 enhances apoptosis by H2O2 in glioma U251 cells
  450. Inhibition of Beclin 1 expression enhances cisplatin-induced apoptosis through a mitochondrial-dependent pathway in human ovarian cancer SKOV3/DDP cells
  451. Inhibition of Beclin-1-mediated autophagy by microRNA-17-5p enhanced the radiosensitivity of glioma cells
  452. Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-ฮบB
  453. Inhibitor of growth protein 4 interacts with Beclin 1 and represses autophagy
  454. Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer
  455. Intensified Beclin-1 mediated by low expression of miR-30a-5p promotes chemoresistance in human small cell lung cancer
  456. Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation
  457. Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAILโ€induced apoptosis
  458. Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity
  459. Interaction of ICP34. 5 with Beclin 1 modulates herpes simplex virus type 1 pathogenesis through control of CD4+ T-cell responses
  460. Interferon-stimulated gene 15 promotes cholesterol efflux by activating autophagy via the miR-17-5p/Beclin-1 pathway in THP-1 macrophage-derived foam cells
  461. Interleukin 7 receptor activates PI3K/Akt/mTOR signaling pathway via downregulation of Beclinโ€1 in lung cancer
  462. Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/Beclin 1
  463. Intracellular bacterium Anaplasma phagocytophilum induces autophagy by secreting substrate Ats-1 that neutralizes the Beclin 1-ATG14L autophagy initiation โ€ฆ
  464. Investigation of JNK/Beclin-1 autophagy Activation in SapC-DOPS Treated Glioma
  465. Involvement of Beclin 1 in engulfment of apoptotic cells
  466. Involvement of Beclinโ€‘1 in axonal protection by shortโ€‘term hyperglycemia against TNFโ€‘induced optic nerve damage
  467. Is Beclin-1 Immunoreactivity More Effective than HBME-1 in Diagnosis of Papillary Thyroid Cancer?
  468. JNK-Bcl-2/Bcl-xL-Bax/Bak pathway mediates the crosstalk between matrine-induced autophagy and apoptosis via interplay with Beclin 1
  469. Justicidin A inhibits AKT/mTOR and activates type III PI3K/Beclin 1 signaling pathways leading to autophagy of human colorectal cancer cells
  470. Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity โ€ฆ
  471. Knockdown of Beclin 1 inhibits vitamin K3โ€‘induced autophagy, but promotes apoptosis of human hepatoma SMMC-7721 cells
  472. Knockdown of Beclinโ€1 impairs epithelialโ€mesenchymal transition of colon cancer cells
  473. Knockdown of miR-372 Inhibits Nerve Cell Apoptosis Induced by Spinal Cord Ischemia/Reperfusion Injury via Enhancing autophagy by Up-regulating Beclin-1
  474. LC3A, LC3B and Beclin-1 Expression in Gastric Cancer
  475. Lentiviral-Mediated Beclin-1 Overexpression Inhibits Cell Proliferation and Induces autophagy of Human Esophageal Carcinoma Eca109 Cell Xenograft in Nude Mice โ€ฆ
  476. Levels of Beclin 1 and LC3 in peripheral blood mononuclear cells of patients with multiple sclerosis and neuromyelitis optica and its significance
  477. Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer โ€ฆ
  478. Lipid trafficking defects increase Beclin-1 and activate autophagy in Niemann-Pick type C disease
  479. Loss of autophagy-related protein Beclin 1 may define poor prognosis in ovarian clear cell carcinomas
  480. Loss of Beclin 1 expression in ovarian cancer: A potential biomarker for predicting unfavorable outcomes
  481. Loss of VAPB regulates autophagy in a Beclin 1-dependent manner
  482. Low Beclin-1 expression predicts improved overall survival in patients treated with immune-modulatory drugs for Multiple Myeloma and identifies autophagy inhibition โ€ฆ
  483. Low Beclin-1 expression predicts improved overall survival in patients treated with immunomodulatory drugs for multiple myeloma and identifies autophagy inhibition โ€ฆ
  484. Low expression of Beclin 1 and elevated expression of HIF-1ฮฑ refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer
  485. Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer
  486. Low expression of MAP1LC3B, associated with low Beclin-1, predicts lymph node metastasis and poor prognosis of gastric cancer
  487. Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer
  488. Lower Beclin-1 mRNA Levels in Pediatric Compared With Adult Patients With Otitis Media With Effusion
  489. Lutein induces autophagy via Beclin-1 upregulation in IEC-6 rat intestinal epithelial cells
  490. lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation โ€ฆ
  491. Macrophage autophagy regulated by miR-384-5p-mediated control of Beclin-1 plays a role in the development of atherosclerosis
  492. Madecassoside prevents Aฮฒ25โ€“35-induced inflammatory responses and autophagy in neuronal cells through the class III PI3K/Beclin-1/Bcl-2 pathway
  493. Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
  494. mda-7/IL-24 mediates Cancer cellโ€“specific death via regulation of miR-221 and the Beclin-1 Axis
  495. Mechanism of ascorbate-induced cell death in human pancreatic cancer cells: Role of Bcl-2, Beclin 1 and autophagy
  496. MEF2D and TH levels and reduces ฮฑ-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated โ€ฆ
  497. Methamphetamine potentiates HIV-1 gp120-mediated autophagy via Beclin-1 and Atg5/7 as a pro-survival response in astrocytes
  498. Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration
  499. Microglial Beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimerโ€™s disease
  500. MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting Beclin-1-mediated autophagy
  501. MicroRNA-216b/Beclin 1 axis regulates autophagy and apoptosis in human Tenonโ€™s capsule fibroblasts upon hydroxycamptothecin exposure
  502. MicroRNA-30a downregulation contributes to chemoresistance of osteosarcoma cells through activating Beclin-1-mediated autophagy
  503. MicroRNAโ€‘30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting Beclin 1 and inhibiting autophagy
  504. MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing Beclin 1-mediated autophagy
  505. MicroRNA-384-5p/Beclin-1 As Potential Indicators For Epigallocatechin Gallate Against Cardiomyocytes Ischemia Reperfusion Injury By Inhibiting autophagy โ€ฆ
  506. miR-101-3p sensitizes hepatocellular carcinoma cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy
  507. MiR-129 triggers autophagic flux by regulating a novel Notch-1/E2F7/Beclin-1 axis to impair the viability of human malignant glioma cells
  508. MiR-129-5p-mediated Beclin-1 suppression inhibits endothelial cell autophagy in atherosclerosis
  509. miR-216b enhances the efficacy of vemurafenib by targeting Beclin-1, UVRAG and ATG5 in melanoma
  510. miR-409-3p sensitizes colon cancer cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy
  511. miR-762 modulates thyroxine-induced cardiomyocyte hypertrophy by inhibiting Beclin-1
  512. Modulatory effects of Beclin 1 on expression of angiopoietin and Tie-2 receptor in human cervical cancer cells
  513. Molecular basis of Bcl-xLโ€™s target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1
  514. Molecular basis of the regulation of Beclin 1-dependent autophagy by the ฮณ-herpesvirus 68 Bcl-2 homolog M11
  515. Molecular characterization and expression analysis of the autophagic gene Beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium
  516. Molecular characterization of Beclin 1 in rare minnow (Gobiocypris rarus) and its expression after waterborne cadmium exposure
  517. Molecular characterization of the autophagy-related gene Beclin-1 from the olive flounder (Paralichthys olivaceus)
  518. Morphine induces Beclin 1-and ATG5-dependent autophagy in human neuroblastoma SH-SY5Y cells and in the rat hippocampus
  519. mTOR dephosphorylation and Beclin-1 mitochondrial translocation activates a caspase-independent programmed cell death and overcomes apoptosis resistance in โ€ฆ
  520. mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
  521. MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages
  522. Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development
  523. Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
  524. Nerve growth factor and autophagy: effect of nasal anti-NGF-antibodies administration on Ambra1 and Beclin-1 expression in rat brain
  525. Neurodegeneration induces upregulation of Beclin 1
  526. Neuroprotective effects of ฮฒ-asarone against 6-hydroxy dopamine-induced parkinsonism via JNK/Bcl-2/Beclin-1 pathway
  527. New Insights Into Beclin-1: Evolution and Pan-Malignancy Inhibitor Activity
  528. NLRX1 Negatively Regulates Group A Streptococcus Invasion and autophagy Induction by Interacting With the Beclin 1โ€“UVRAG Complex
  529. Norcantharidin induces autophagy-related prostate cancer cell death through Beclin-1 upregulation by miR-129-5p suppression
  530. Novel Insight into the autophagy-Independent Functions of Beclin 1 in Tumor Growth
  531. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 โ€ฆ
  532. NS5ATP9 Promotes Beclin 1โ€Dependent Starvationโ€Induced autophagy of Hepatoblastoma Cells
  533. Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy
  534. Nur77 promotes cigarette smokeโ€‘induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin-1
  535. O4-05-02: Deficiency of the Beclin 1 autophagy protein promotes Alzheimerโ€™s disease pathology
  536. Obatoclax induces Atg7-dependent autophagy independent of Beclin-1 and BAX/BAK
  537. Obatoclax induces Beclin 1โ€and ATG 5โ€dependent apoptosis and autophagy in adenoid cystic carcinoma cells
  538. Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells
  539. Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
  540. One novel curcumin derivative ZYX01 induces autophagy of human non-small lung cancer cells A549 through AMPK/ULK1/Beclin-1 signaling pathway.
  541. oral cancer CAL 27 cells through the reactive oxygen species production and caspaseโ€dependent pathways and associated with beclinโ€1โ€induced cell autophagy
  542. Over expression of GPR30, indicating poor prognosis and promoting proliferation, upregulates Beclin-1 expression via p38MAPK signaling in esophageal โ€ฆ
  543. Over-expression of Beclin-1 in gallbladder carcinoma and its relationship with prognosis
  544. Overexpression of the autophagic Beclin-1 protein clears mutant ataxin-3 and alleviates Machadoโ€“Joseph disease
  545. Ox-LDL-induced lncRNA MALAT1 promotes autophagy in human umbilical vein endothelial cells by sponging miR-216a-5p and regulating Beclin-1 expression
  546. P-0050 The Significance of Expression of Beclin 1 and LC3 in Stage II or III Colorectal Cancers
  547. P-035 Marked upregulation of Bcl-2 and low expression of Beclin 1 is associated with MDS and disease progression
  548. p53 and Beclin 1 in Caenorhabditis elegansare involved in cell death and DNA damage repair
  549. p53/PCDH17/Beclin-1 Proteins as Prognostic Predictors for Urinary Bladder Cancer
  550. p65/RelA binds and activates the Beclin 1 promoter
  551. Partial Beclin 1 silencing aggravates doxorubicin-and Fas-induced apoptosis in HepG2 cells
  552. Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis
  553. Peptides derived from evolutionarily conserved domains in Beclin-1 and Beclin-2 enhance the entry of lentiviral vectors into human cells
  554. Phosphorylation of Beclin 1 by BCR-ABL suppresses autophagy in CML
  555. Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL
  556. Phosphorylation of Beclin-1 by BCR-ABL suppresses autophagy in chronic myeloid leukemia
  557. Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein
  558. Polyglutamine tracts regulate Beclin 1-dependent autophagy
  559. positron emission tomography maximal standardized uptake value in predicting outcomes of colon liver metastases and that valueโ€™s association with Beclin-1 โ€ฆ
  560. Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation
  561. Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia
  562. Preconditioning Effect of High-Intensity Aerobic Training on Myocardial Ischemia-Reperfusion Injury and Beclin-1 Gene Expression in Rats
  563. Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with โ€ฆ
  564. Prenatal exposure to hypoxia induced Beclin 1 signaling-mediated renal autophagy and altered renal development in rat fetuses
  565. Proctective effect of microRNA-30a on regulating Beclin-1 expression in hypoxia-reoxygenated neonatal rat cardiomyocytes [J]
  566. Prodigiosin-emerged PI3K/Beclin-1-independent pathway elicits autophagic cell death in doxorubicin-sensitive and-resistant lung cancer
  567. Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis
  568. Prognostic and clinicopathological value of Beclin-1 expression in hepatocellular carcinoma: a meta-analysis
  569. Prognostic impact of autophagic markers LC3, Beclin 1 and p62/sequestosome 1 in colon carcinomas from patients treated in 5-FU-based adjuvant therapy trials
  570. Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy
  571. Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS โ€ฆ
  572. Prognostic role of Beclin-1 in locally advanced non-small cell lung cancer in patients receiving docetaxel-platinum induction chemotherapy
  573. Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma
  574. Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma
  575. Prognostic significance of Beclin-1 expression in colorectal cancer: a meta-analysis
  576. Prognostic significance of Beclin-1 expression in laryngeal squamous cell carcinoma
  577. Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer
  578. Progress of Beclin 1 in regulating the myocardial autophagy and the relationship between cardiovascular diseases
  579. Promotion of tumorigenesis by heterozygous disruption of the Beclin 1 autophagy gene
  580. Protective effects of DJ-1 via antagonizing ROS-induced Beclin-1 up-regulation in hypoxia-reoxygenated HL-1 cardiomyocytes
  581. protects against 6โ€hydroxydopamineโ€induced damage in parkinsonian rat mesencephalon by regulating autophagy: downโ€expression Beclinโ€1 and light chain 3B โ€ฆ
  582. Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
  583. Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration
  584. PS 1602; Lung Cancer: Role of P38 MAP Kinase of Beclin 1-Dependent autophagy in Alexidine Treated Lung Cancer Cells
  585. PtdIns (3) P-bound UVRAG coordinates Golgiโ€“ER retrograde and Atg9 transport by differential interactions with the ER tether and the Beclin 1 complex
  586. RACK1 promotes autophagy by enhancing the Atg14L-Beclin 1-Vps34-Vps15 complex formation upon phosphorylation by AMPK
  587. Rapamycin inhibits cardiac hypertrophy by promoting autophagy via the MEK/ERK/Beclin-1 pathway
  588. Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic โ€ฆ
  589. Regulation of amyloid precursor protein processing by the Beclin 1 complex
  590. Regulation of an ATG7-Beclin 1 program of autophagic cell death by caspase-8
  591. Regulation of ATG6/Beclin-1 homologs by abiotic stresses and hormones in rice (Oryza sativa L.)
  592. Regulation of autophagy by a Beclin 1-targeted microRNA, miR-30a, in cancer cells
  593. Regulation of autophagy by Beclin 1 in the heart
  594. Regulation of Aฮฒ pathology by Beclin 1: a protective role for autophagy?
  595. Regulation of Beclin 1 in autophagy
  596. Regulation of Beclin 1 protein phosphorylation and autophagy by protein phosphatase 2A (PP2A) and death-associated protein kinase 3 (DAPK3)
  597. Regulation of estrogenic effects by Beclin 1 in breast cancer cells
  598. Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1
  599. Regulation of macroautophagy by mTOR and Beclin 1 complexes
  600. Regulation of the autophagic bcl-2/Beclin 1 interaction
  601. Regulation of the endolysosomal pathway by Beclin-1 and its role in the proteolytic processing of the amyloid precursor protein
  602. Regulation of the transcription factor EB-PGC1ฮฑ axis by Beclin-1 controls mitochondrial quality and cardiomyocyte death under stress
  603. Regulation of the tumor-suppressor Beclin 1 by distinct ubiquitination cascades
  604. Regulation on Beclin-1 expression by mTOR in CoCl2-induced HT22 cell ischemia-reperfusion injury
  605. Relationship between autophagy-related genes Beclin-1 and MAP1LC3 expression and biological characteristics of oral cancer
  606. Relationship between bcl-2, bax, Beclin-1, and cathepsin-D proteins during postovulatory follicular regression in fish ovary
  607. Requirement of autophagy Proteins Beclin-1 and Map1-LC3b in the Induction of Innate and Adaptive Immune Responses to Respiratory Syncytial Virus Infection.
  608. Research of the relationship of ubiquinone and Beclin-1 and liver mitochondria
  609. Retro-inverso TAT-Beclin-1 induces synovial fibrosis and does not protect cartilage from degeneration in a mouse model of OA
  610. Rhes, a striatal-selective protein implicated in Huntington disease, binds Beclin-1 and activates autophagy
  611. Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death โ€ฆ
  612. RNase L cleavage products promote switch from autophagy to apoptosis by caspase-mediated cleavage of Beclin-1
  613. Robust anticancer efficacy of a biologically synthesized tumor acidity-responsive and autophagy-inducing functional Beclin 1
  614. Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death
  615. Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon โ€ฆ
  616. Role of BEC-1/Beclin 1 and autophagy Genes in C.elegans Germline Cell Proliferation
  617. Role of Beclin 1 and autophagy in vitiligo
  618. Role of Beclin 1 gene in autophagy and apoptosis of SW620 cells
  619. Role of Beclin 1-dependent autophagy in cardioprotection of ischemic preconditioning
  620. Role of Beclin-1-mediated autophagy in the survival of pediatric leukemia cells
  621. Role of membrane association and Atg14-dependent phosphorylation in Beclin-1-mediated autophagy
  622. Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
  623. Role of the Beclin 1 Network in the Cross-Regulation Between autophagy and Apoptosis
  624. Roles of autophagyโ€‘related genes Beclinโ€‘1 and LC3 in the development and progression of prostate cancer and benign prostatic hyperplasia
  625. ROS-mediated JNK activation contributes to HBx-induced autophagy via regulating Beclin-1/Bcl-2 interaction
  626. Ruthenium complex ฮ›-WH0402 induces hepatocellular carcinoma LM6 (HCCLM6) cell death by triggering the Beclin-1-dependent autophagy pathway
  627. โ€˜S1-03-04: The autophagy protein Beclin 1 is reduced in early Alzheimerโ€™s disease and regulates Abeta accumulation in vivo
  628. Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein
  629. Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins-PI3K, ERK (1/2), AMPK and Beclin-1 during early ischemia-reperfusion injury โ€ฆ
  630. Selective 14-3-3ฮณ Upregulation Promotes Beclin-1-LC3-Autophagic Influx via ฮฒ-Catenin Interaction in Starved Neurons In Vitro and In Vivo
  631. Serum level of the autophagy biomarker Beclin-1 in patients with diabetic kidney disease
  632. Serum level of the autophagy biomarker Beclin-1 in patients with diabetic nephropathy
  633. Serum response factor promotes dopaminergic neuron survival via activation of Beclin 1-dependent autophagy
  634. Signaling by the toll-like receptors induces autophagy through modification of Beclin 1: Molecular mechanism
  635. Significance of Beclin-1, hypoxia-inducible factor-1ฮฑ, and nuclear factor-ฮบB/p65 expression in colorectal carcinoma: an immuohistochemical study
  636. Silencing the autophagy-specific gene Beclin-1 contributes to attenuated hypoxia-induced vasculogenic mimicry formation in glioma
  637. Simulated ischemia/reperfusion-induced p65-Beclin 1-dependent autophagic cell death in human umbilical vein endothelial cells
  638. Single-prolonged-stress-induced changes in autophagy-related proteins Beclin-1, LC3, and p62 in the medial prefrontal cortex of rats with post-traumatic stress โ€ฆ
  639. SLAM is a microbial sensor which regulates bacterial phagosome functions in macrophages by recruiting a Vps34/Beclin 1/UVRAG complex (112.8)
  640. Sorting through the roles of Beclin 1 in microglia and neurodegeneration
  641. species-mediated c-Jun NH2-terminal kinase activation contributes to hepatitis B virus X protein-induced autophagy via regulation of the Beclin-1/Bcl-2 interaction
  642. Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death
  643. Spliced XBP1 promotes macrophage survival and autophagy by interacting with Beclin-1
  644. Stat3 inhibits Beclin 1 expression through recruitment of HDAC3 in nonsmall cell lung cancer cells
  645. Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol
  646. Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein
  647. Structural Transitions in Conserved, Ordered Beclin 1 Domains Essential to Regulating autophagy
  648. Tamoxifen overrides autophagy inhibition in Beclin-1-deficient glioma cells and their resistance to adenovirus-mediated oncolysis via upregulation of PUMA and BAX
  649. Tanshinone IIA induces cell death via Beclinโ€1โ€dependent autophagy in oral squamous cell carcinoma SCCโ€9 cell line
  650. Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy
  651. Targeted Knockout of Beclin-1 Reveals an Essential Function in Ovary and Testis
  652. Targeting AR-Beclin 1 complex-modulated growth factor signaling increases the antiandrogen Enzalutamide sensitivity to better suppress the castration-resistant โ€ฆ
  653. Targeting Beclin 1 for viral subversion of macroautophagy
  654. Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin ฮฒ1/Src signaling โ€ฆ
  655. Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells
  656. Targeting the potent Beclin 1โ€“UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking
  657. Tetraarsenic hexoxide induces Beclin-1-induced autophagic cell death as well as caspase-dependent apoptosis in U937 human leukemic cells
  658. Tetrahydroxy stilbene glucoside improved the behavioral disorders of APP695V717I transgenic mice by inhibiting the expression of Beclin-1 and LC3-II
  659. Tetrandrine induces apoptosis Via caspaseโ€8,โ€9, andโ€3 and poly (ADP ribose) polymerase dependent pathways and autophagy through beclinโ€1/LC3โ€I, II signaling โ€ฆ
  660. The Antiapoptotic Protein BCL-2 Has Also an Antiautophagy Role Through Beclin 1 Inhibition
  661. The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans
  662. The autophagy effector Beclin 1: a novel BH3-only protein
  663. The autophagy molecule Beclin 1 maintains persistent activity of NF-ฮบB and Stat3 in HTLV-1-transformed T lymphocytes
  664. The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone
  665. The autophagy-related Beclin-1 protein requires the coiled-coil and BARA domains to form a homodimer with submicromolar affinity
  666. The autophagy-related protein Beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid ฮฒ accumulation in mice
  667. The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells
  668. The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells
  669. The Beclin 1 interactome
  670. The Beclin 1 network regulates autophagy and apoptosis
  671. The Beclin 1โ€“VPS34 complexโ€“at the crossroads of autophagy and beyond
  672. The BH3 mimetic S1 induces autophagy through ER stress and disruption of Bcl-2/Beclin 1 interaction in human glioma U251 cells
  673. The cellular autophagy markers Beclin-1 and LC3B-II are increased during reperfusion in fibrillated mouse hearts
  674. The change and effect of Beclin 1 on cytotoxicity of ovarian cancer cells induced by MG132
  675. The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex
  676. The cytoplasmic nuclear shuttling of Beclin 1 in neurons with Alzheimerโ€™s disease-like injury
  677. The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid
  678. The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells
  679. The Effect of Overexpressed Beclin 1 on Esophageal Cancer (Eca109) Cells in vivo [J]
  680. The EGFR antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1ฮฑ and Bcl-2 and activating the Beclin-1/hVps34 complex
  681. The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1ฮฑ and Bcl-2 and activating the Beclin 1/hVps34 โ€ฆ
  682. The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy, and tumor suppressor function
  683. The expression of Beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
  684. The Expression of Beclin-1 in Hepatocellular Carcinoma and Non-Tumor Liver Tissue: A Meta-Analysis
  685. The expression of Beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance
  686. The expression of the autophagy gene Beclin-1 mRNA and protein in ectopic and eutopic endometrium of patients with endometriosis
  687. The expressions and correlation of bcl-2 and Beclin-1 in pancreatic cancer
  688. The Function of Bcl-2/Beclin-1 Complex in autophagy Regulation [J]
  689. The heme oxygenase-1 inhibitor ZnPPIX induces non-canonical, Beclin 1-independent, autophagy through p38 MAPK pathway
  690. The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1
  691. The inositol 1, 4, 5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
  692. The novel BH-3 mimetic apogossypolone induces Beclin-1-and ROS-mediated autophagy in human hepatocellular carcinoma cells
  693. The novel pterostilbene derivative ANK-199 induces autophagic cell death through regulating PI3 kinase class III/Beclin 1/Atgโ€‘related proteins in cisplatin โ€ฆ
  694. The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
  695. The potential of Beclin 1 as a therapeutic target for the treatment of breast cancer
  696. The potential role of Beclin 1 and Bcl-2 expression in renal cell carcinoma: an immunohistochemical study
  697. The prognostic role of Beclin 1 protein expression in high-grade gliomas
  698. The prognostic value of autophagy-related markers Beclin-1 and microtubule-associated protein light chain 3B in cancers: a systematic review and meta-analysis
  699. The PVT1/miR-216b/Beclin-1 regulates cisplatin sensitivity of NSCLC cells via modulating autophagy and apoptosis
  700. The receptor Slamf1 regulates membrane fusion and NOX2 activity by recruiting a Beclin-1/Vps34/UVRAG complex
  701. The relation of Beclin 1 and bcl-2 expressions in high grade prostatic intraepithelial neoplasia and prostate adenocarcinoma: A tissue microarray study
  702. The role of autophagy and Beclin-1 in radiotherapy-induced apoptosis in thyroid carcinoma cells
  703. The role of Beclin 1 in IR-induced crosstalk between autophagy and G2/M cell cycle arrest
  704. The role of Beclin 1 in SDT-induced apoptosis and autophagy in human leukemia cells
  705. The role of Beclin 1 interacting proteins and Beclin 1 post-translational modification in autophagy regulation.
  706. The Role of Beclin 1-Dependent autophagy in Cancer
  707. The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimerโ€™s Disease
  708. The Role of Beclin-1 deacetylation on autophagic flux in Alzheimerโ€™s Disease
  709. The role of Beclin-1 expression in patients with gastric cancer: a meta-analysis
  710. The roles of oxidative stress and Beclin-1 in the autophagosome clearance impairment triggered by cardiac arrest
  711. The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
  712. The synthetic oleanane triterpenoid HIMOXOL induces autophagy in breast cancer cells via ERK1/2 MAPK pathway and Beclin-1 up-regulation
  713. The transcriptional coactivator YAP1 is overexpressed in osteoarthritis and promotes its progression by interacting with Beclin-1
  714. The Urotsa Bladder Cell Model For Heavy Metal Carcinogenesis: Characterization With Respect To The Role Of Beclin-1 And Sparc Expression
  715. The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with Beclin 1 and B-cell CLL โ€ฆ
  716. The VMP1-Beclin 1 interaction regulates autophagy induction
  717. The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway
  718. Tissue transglutaminase cross-links Beclin 1 and regulates autophagy in MPP+-treated human SH-SY5Y cells
  719. to adenosineโ€induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3Kโ€AKTโ€mTOR and beclinโ€1 signaling โ€ฆ
  720. to autophagic cell death in epstein-barr virus-associated nasal natural killer/T-cell lymphomas: an immunohistochemical analysis of Beclin-1, LC3, mitochondria (AE-1 โ€ฆ
  721. Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy
  722. Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1
  723. TRAF6 and A20 Regulate Lysine 63โ€“Linked Ubiquitination of Beclin-1 to Control TLR4-Induced autophagy
  724. TRIM22 regulates macrophage autophagy and enhances Mycobacterium tuberculosis clearance by targeting the nuclear factorโ€“multiplicity ฮบB/Beclin 1 pathway
  725. TRIM50 regulates Beclin 1 proautophagic activity
  726. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
  727. Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway
  728. Tyrosine kinase inhibition increases functional parkinโ€Beclinโ€1 interaction and enhances amyloid clearance and cognitive performance
  729. Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
  730. Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L
  731. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
  732. ULK1 targets Beclin-1 in autophagy
  733. Unleashing the Ambra1-Beclin 1 complex from dynein chains: Ulk1 sets Ambra1 free to induce autophagy
  734. Upexpression of Beclin-1-dependent autophagy protects against beta-amyloid-induced cell injury in PC12 cells
  735. Upregulation of Beclin 1 in the ischemic penumbra
  736. Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death
  737. Upregulation of Beclin-1 expression in DU-145 cells following low-frequency ultrasound irradiation combined with microbubbles
  738. Upregulation of myeloid cell leukemia-1 potentially modulates Beclin-1-dependent autophagy in ischemic stroke in rats
  739. Use of the essential autophagy protein Beclin 1 to regulate DNA damage response and predict response to chemoradiation in rectal cancer.
  740. USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1
  741. USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclinโ€1
  742. Valosinโ€‘containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NFโ€‘ฮบฮฒ/beclinโ€‘1 signaling pathway
  743. Virus spread and immune response following anterior chamber inoculation of HSV-1 lacking the Beclin-binding domain (BBD)
  744. Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death
  745. WASH inhibits autophagy through suppression of Beclin 1 ubiquitination
  746. Why doesnโ€™t Beclin 1, a BH3-only protein, suppress the anti-apoptotic function of Bcl-2?
  747. Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells
  748. XBP1 mRNA splicing triggers an autophagic response in endothelial cells through Beclin-1 transcriptional activation
  749. XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFฮบB activation
  750. Zoledronate induces autophagic cell death in human umbilical vein endothelial cells via Beclin-1 dependent pathway activation
  751. ฮฑ-Asarone blocks 7ฮฒ-hydroxycholesterol-exposed macrophage injury through blocking elF2ฮฑ phosphorylation and prompting Beclin-1-dependent autophagy
  752. ฮฒ-asarone improves learning and memory and reduces Acetyl Cholinesterase and Beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating Beclin-1 โ€ฆ
  753. ฮฒ-asarone prevents Aฮฒ25-35-induced inflammatory responses and autophagy in SH-SY5Y cells: Down expression Beclin-1, LC3B and up expression Bcl-2
  754. ฮฒ-Asarone protects PC12 cells against OGD/R-induced injury via attenuating Beclin-1-dependent autophagy
  755. ฮฒ-Asarone Regulates ER Stress and autophagy Via Inhibition of the PERK/CHOP/Bcl-2/Beclin-1 Pathway in 6-OHDA-Induced Parkinsonian Rats
  756. 14 negatively regulates toll-like receptor 4-mediated signaling and autophagy induction by inhibiting ubiquitination of TAK1-binding protein 2 and Beclin 1
  757. 14-3-3ฯ„ Regulates Beclin 1 and Is Required for autophagy
  758. 17-hydroxy wortmannin restores TRAILโ€™s response by ameliorating increased Beclin 1 level and autophagy function in TRAIL-resistant colon cancer cells
  759. 18ฮฑ-Glycyrrhetinic acid lethality for neuroblastoma cells via de-regulating the Beclin-1/Bcl-2 complex and inducing apoptosis
  760. 1-Methyl-4-phenylpyridinium-induced cell death via autophagy through a Bcl-2/Beclin 1 complex-dependent pathway
  761. 286: Regulation of autophagy by E3 ubiquitin ligase Triad3A through Beclin 1 ubiquitination
  762. 34aโ€5p was involved in chronic intermittent hypoxiaโ€induced autophagy of human coronary artery endothelial cells via Bclโ€2/Beclin 1 signal transduction pathway
  763. 433P High Beclin-1 expression predicts prolonged survival in locally advanced non-small cell lung cancer receiving docetaxel-platinum induction chemotherapy

Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

0
    0
    Your Cart
    Your cart is emptyReturn to Shop