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Ameliorates Memory Impairment
Ameliorates Memory Impairment
Nasal Colivelin treatment ameliorates memory impairment related to Alzheimerโs disease
Arctigenin effectively ameliorates memory impairment in Alzheimerโs disease model mice targeting both ฮฒ-amyloid production and clearance
Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a D-galactose-induced accelerated aging mouse model
Tanshinone I enhances learning and memory, and ameliorates memory impairment in mice via the extracellular signalโregulated kinase signalling pathway
Gami-Chunghyuldan ameliorates memory impairment and neurodegeneration induced by intrahippocampal Aฮฒ1โ42 oligomer injection
Angelica polysaccharide ameliorates memory impairment in Alzheimerโs disease rat through activating BDNF/TrkB/CREB pathway
Dihydromyricetin ameliorates memory impairment induced by acute sleep deprivation
Ferulic acid ameliorates memory impairment in d-galactose-induced aging mouse model
Chronic ghrelin administration restores hippocampal longโterm potentiation and ameliorates memory impairment in rat model of Alzheimerโs disease
Dexmedetomidine ameliorates memory impairment in sleep-deprived mice
Guarana (Paullinia cupana) ameliorates memory impairment and modulates acetylcholinesterase activity in Poloxamer-407-induced hyperlipidemia in ratย โฆ
Berberine exerts an anticonvulsant effect and ameliorates memory impairment and oxidative stress in a pilocarpine-induced epilepsy model in the rat
Treadmill exercise ameliorates memory impairment through ERK-Akt-CREB-BDNF signaling pathway in cerebral ischemia gerbils
Simvastatin ameliorates memory impairment and neurotoxicity in streptozotocin-induced diabetic mice
Anticonvulsant effect of piperine ameliorates memory impairment, inflammation and oxidative stress in a rat model of pilocarpine-induced epilepsy
Xanthohumol ameliorates memory impairment and reduces the deposition of ฮฒ-amyloid in APP/PS1 mice via regulating the mTOR/LC3II and Bax/Bcl-2 signallingย โฆ
Qingxin kaiqiao fang ameliorates memory impairment and inhibits apoptosis in APP/PS1 double transgenic mice through the MAPK pathway
(โ)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouseย โฆ
GJ-4 ameliorates memory impairment in focal cerebral ischemia/reperfusion of rats via inhibiting JAK2/STAT1-mediated neuroinflammation
Deferiprone ameliorates memory impairment in Scopolamine-treated rats: The impact of its iron-chelating effect on ฮฒ-amyloid disposition
The phosphodiesterase type-5 inhibitor, tadalafil, improves depressive symptoms, ameliorates memory impairment, as well as suppresses apoptosis and enhancesย โฆ
2,2โฒ,4โฒโTrihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice
Phytoestrogen ฮฑ-zearalanol ameliorates memory impairment and neuronal DNA oxidation in ovariectomized mice
Oxymatrine ameliorates memory impairment in diabetic rats by regulating oxidative stress and apoptosis: involvement of NOX2/NOX4
2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2-and H3ย โฆ
Danggui-Jakyak-San ameliorates memory impairment and increase neurogenesis induced by transient forebrain ischemia in mice
17-AAG post-treatment ameliorates memory impairment and hippocampal CA1 neuronal autophagic death induced by transient global cerebral ischemia
Cotinine ameliorates memory and learning impairment in senescent mice
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats
Kisspeptin-13 ameliorates memory impairment induced by streptozotocin in male rats via cholinergic system
Sodium valproate ameliorates memory impairment and reduces the elevated levels of apoptotic caspases in the hippocampus of diabetic mice
Preischemic treadmill exercise ameliorates memory impairment and microvasculature damage in rat model of chronic cerebral hypoperfusion
A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice
Combination of proanthocyanidins extracted from lotus seedpod and l-cysteine ameliorates memory impairment induced by alcohol and scopolamine in mice
Dangguijakyak-san ameliorates memory deficits in ovariectomized mice by upregulating hippocampal estrogen synthesis
DMTHB ameliorates memory impairment in Alzheimerโs disease mice through inhibition of IL-16 signaling
7-Deoxy-trans-dihydronarciclasine Reduces ฮฒ-Amyloid and Ameliorates Memory Impairment in a Transgenic Model of Alzheimerโs Disease
Physical exercise ameliorates memory impairment in rat pups with maternal lipopolysaccharide-induced cerebral palsy
Biflorin ameliorates memory impairments induced by cholinergic blockade in mice
Fructus corni officinalis water extract ameliorates memory impairment and beta amyloid (Aฮฒ) clearance by LRP-1 expression in the hippocampus of a rat model ofย โฆ
Correction to: 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergicย โฆ
Intravenous adipose-derived stem cells transplantation ameliorates memory impairment in moderate traumatic brain injury rats via the phosphorylation ofย โฆ
A novel heptapeptide, GPPGPAG transfers to the brain, and ameliorates memory dysfunction and dendritic atrophy in Alzheimerโs disease model mice
Human placenta extract ameliorates memory dysfunction and dendritic atrophy in a 5XFAD mouse model of A lzheimerโs disease
AMPK ameliorates tau acetylation and memory impairment through Sirt1
Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment
Inhibition of central angiotensin converting enzyme ameliorates scopolamine induced memory impairment in mice: role of cholinergic neurotransmission, cerebralย โฆ
Lactobacillus pentosus var. plantarum C29 ameliorates ageโdependent memory impairment in Fischer 344 rats
The AMPA receptor allosteric potentiator PEPA ameliorates post-ischemic memory impairment
Antioxidative activity and ameliorative effects of memory impairment of sulfurโcontaining compounds in Allium species
A multifunctional compound ebselen reverses memory impairment, apoptosis and oxidative stress in a mouse model of sporadic Alzheimerโs disease
Effects of idebenone on memory impairment induced in ischemic and embolization models of cerebrovascular disturbance in rats
Chronic inhibition of central Angiotensin-converting enzyme ameliorates colchicine-induced memory impairment in mice
Catalog Number: T0229 CAS Number: 123441-03-2 Molecular Formula: C14H22N2O2 Molecular Weight: 250.34 Appearance: Solid
Rehmannia glutinosa ameliorates scopolamine-induced learning and memory impairment in rats
A mini-review of the mechanisms of glucose memory enhancement
Activation of ERฮฑ and/or ERฮฒ ameliorates cognitive impairment and apoptosis in streptozotocin-induced diabetic mice
Baicalein ameliorates aฮฒ-induced memory deficits and neuronal atrophy via inhibition of PDE2 and PDE4
Juglanin ameliorates LPS-induced neuroinflammation in animal models of Parkinsonโs disease and cell culture via inactivating TLR4/NF-ฮบB pathway
Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-inducedย โฆ
Effects of osthole microemulsion by nasal administration on the cholinergic pathway in mice treated with scopolamine
Taking advantage of the selectivity of histone deacetylases and phosphodiesterase inhibitors to design better therapeutic strategies to treat Alzheimerโsย โฆ
PMC-12, a traditional herbal medicine, enhances learning memory and hippocampal neurogenesis in mice
Pharmacological studies of a novel prolyl endopeptidase inhibitor, JTP-4819, in rats with middle cerebral artery occlusion
ERฮฑ and/or ERฮฒ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice
Mangiferin ameliorates scopolamine-induced learning deficits in mice
Treadmill exercise ameliorates impairment of spatial learning memory in pups born to old and obese mother rats
Treadmill exercise ameliorates short-term memory impairment by suppressing hippocampal neuroinflammation in poloxamer-407-induced hyperlipidemia rats
Berberine chloride improved synaptic plasticity in STZ induced diabetic rats
Memantine improves memory for taste-avoidance learning in day-old chicks exposed to isolation stress
Cognitive Ameliorating Effect of Acanthopanax koreanum Against ScopolamineโInduced Memory Impairment in Mice
Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice
Annona atemoya leaf extract ameliorates cognitive impairment in amyloid-ฮฒ injected Alzheimerโs disease-like mouse model
Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor- Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model ofย โฆ
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimerโs disease
Protective effects of Colivelin against Alzheimerโs disease in a PDAPP mouse model
Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimerโs disease mice
Hilar interneuron vulnerability distinguishes aged rats with memory impairment
Ethanolic extract of the seed of zizyphus jujuba var. spinosa ameliorates cognitive impairment induced by cholinergic blockade in mice
Geniposide ameliorates cognitive deficits by attenuating the cholinergic defect and amyloidosis in middle-aged Alzheimer model mice
DL-3-n-butylphthalide (NBP) ameliorates cognitive deficits and CaMKII-mediated long-term potentiation impairment in the hippocampus of diabetic db/db mice
Arctigenin ameliorates renal impairment and inhibits endoplasmic reticulum stress in diabetic db/db mice
Silymarin sex-dependently improves cognitive functions and alters TNF-ฮฑ, BDNF, and glutamate in the hippocampus of mice with mild traumatic brain injury
The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
Shunaoxin dropping pill, a Chinese herb compound preparation, attenuates memory impairment in D-galactose-induced aging mice
Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat
Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination
Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice
Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms
Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes
Cajaninstilbene Acid Ameliorates Cognitive Impairment Induced by Intrahippocampal Injection of Amyloid-ฮฒ1โ42 Oligomers
Minocycline ameliorates d-galactose-induced memory deficits and loss of Arc/Arg3.1 expression
STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17
Rifampicin ameliorates lithium-pilocarpine-induced seizures, consequent hippocampal damage and memory deficit in rats: Impact on oxidative, inflammatory andย โฆ
Casticin ameliorates scopolamine-induced cognitive dysfunction in mice
TGF-ฮฒ1 restores hippocampal synaptic plasticity and memory in Alzheimer model via the PI3K/Akt/Wnt/ฮฒ-catenin signaling pathway
Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxicโischemic brain injury
Procognitive effect of AC-3933 in aged mice, and synergistic effect of combination with donepezil in scopolamine-treated mice
Selenofuranoside improves long-term memory deficits in rats after exposure to monosodium glutamate: Involvement of Na+, K+-ATPase activity
Effect of Codonopsis lanceolata with steamed and fermented process on scopolamine-induced memory impairment in mice
Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of ฮฒ-amyloid
Effect of Berberine Chloride on Long Term Potentiation (LTP) at Dentate Gyrus in Streptozotocin-Induced Diabetic Rats
Berberine protects against memory impairment and anxiogenic-like behavior in rats submitted to sporadic Alzheimerโs-like dementia: involvement ofย โฆ
STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimerโs disease animal model
Inhibition of glutaminyl cyclase ameliorates amyloid pathology in an animal model of Alzheimerโs disease via the modulation of ฮณ-secretase activity
Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of ฮฒ-amyloid in APP/tau/PS1 mouse model of Alzheimerโsย โฆ
Effect of hachimijiogan on memory impairment induced by betaโamyloid combined with cerebral ischemia in rats
A natural BACE1 and GSK3ฮฒ dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimerโs mice by attenuating amyloidโฮฒ andย โฆ
Autophagy impairment by caspaseโ1โdependent inflammation mediates memory loss in response to ฮฒโAmyloid peptide accumulation
Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimerโs disease: Modulation of hippocampal neurogenesis and apoptosis as underlyingย โฆ
Dietary astaxanthin can accumulate in the brain of rats
Scutellarin Ameliorates Learning and Memory Deficit via Suppressing -Amyloid Formation and Microglial Activation in Rats with Chronic Cerebral Hypoperfusion
Treadmill exercise prevents learning and memory impairment in Alzheimerโs disease-like pathology
Lapatinib ditosylate rescues memory impairment in D-galactose/ovariectomized rats: Potential repositioning of an anti-cancer drug for the treatment of Alzheimerโsย โฆ
Berberine ameliorates brain inflammation in poloxamer 407-induced hyperlipidemic rats
Oral administration of gintonin attenuates cholinergic impairments by scopolamine, amyloid-ฮฒ protein, and mouse model of Alzheimerโs disease
Picrorhiza kurroa Prevents Memory Deficits by Inhibiting NLRP3 Inflammasome Activation and BACE1 Expression in 5xFAD Mice
Neuroprotective effects of salvianolic acid B on an Aฮฒ25โ35 peptide-induced mouse model of Alzheimerโs disease
CAPE-pNO2 ameliorates diabetic brain injury through modulating Alzheimerโs disease key proteins, oxidation, inflammation and autophagy via a Nrf2-dependentย โฆ
Effects of propentofylline, a NGF synthesis stimulator, on alterations in muscarinic cholinergic receptors induced by basal forebrain lesion in rats
Leonurine ameliorates D-galactose-induced aging in mice through activation of the Nrf2 signalling pathway
The effect of ghrelin on MK-801 induced memory impairment in rats
Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease
Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice
The Impact of Bdnf Gene Deficiency to the Memory Impairment and Brain Pathology of APPswe/PS1dE9 Mouse Model of Alzheimerโs Disease
Sirtuin-2 inhibition affects hippocampal functions and sodium butyrate ameliorates the reduction in novel object memory, cell proliferation, and neuroblastย โฆ
Colivelin ameliorates impairments in cognitive behaviors and synaptic plasticity in APP/PS1 transgenic mice
Neferine alleviates memory and cognitive dysfunction in diabetic mice through modulation of the NLRP3 inflammasome pathway and alleviation of endoplasmicย โฆ
Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways
Companion retards the development of memory deficit in APP/PS1 mice
Glycyrrhiza and Uncaria Hook contribute to protective effect of traditional Japanese medicine yokukansan against amyloid ฮฒ oligomer-induced neuronal death
1950 MHz electromagnetic fields ameliorate Aฮฒ pathology in Alzheimerโs disease mice
ADAM10 in Alzheimerโs disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
The KATP channel opener, nicorandil, ameliorates brain damage by modulating synaptogenesis after ischemic stroke
The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice
Effects of idebenone, a cerebral metabolism activator, on muricidal behavior in rats with raphe lesions
Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade
Butterbur leaves attenuate memory impairment and neuronal cell damage in amyloid beta-induced alzheimerโs disease models
Medicinal plants and dementia therapy: herbal hopes for brain aging?
Neuroprotective effects of INT-777 against Aฮฒ1โ42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice
Silibinin alleviates the learning and memory defects in overtrained rats accompanying reduced neuronal apoptosis and senescence
Ethanol Extract and Saponin of Platycodon grandiflorum Ameliorate Scopolamine-Induced Amnesia in Mice
Berberine and neurodegeneration: A review of literature
Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimerโs disease
The effect of long-term environmental enrichment in chronic cerebral hypoperfusion-induced memory impairment in rats
In vitro importance of probiotic Lactobacillus plantarum related to medical field
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
The multiple T-maze in vivo testing of the neuroprotective effect of humanin analogues
Postsynaptic GluR2 involved in amelioration of Aฮฒ-induced memory dysfunction by KAIXIN-San through rescuing hippocampal LTP in mice
PDE5 exists in human neurons and is a viable therapeutic target for neurologic disease
Possible Therapeutic Effect of Exercise for Incurable Diseases
A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals
Genistein prevents hypoxia-induced cognitive dysfunctions by ameliorating oxidative stress and inflammation in the hippocampus
Green tea extract containing enhanced levels of epimerized catechins attenuates scopolamine-induced memory impairment in mice
Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice
Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress
A synbiotic consisting of Lactobacillus plantarum S58 and hull-less barley ฮฒ-glucan ameliorates lipid accumulation in mice fed with a high-fat diet by activating AMPKย โฆ
A novel small Odorranalectin-bearing cubosomes: preparation, brain delivery and pharmacodynamic study on amyloid-ฮฒ25โ35-treated rats following intranasalย โฆ
Suan-Zao-Ren Decoction ameliorates synaptic plasticity through inhibition of the Aฮฒ deposition and JAK2/STAT3 signaling pathway in AD model of APP/PS1ย โฆ
Caffeine reduces time-of-day effects on memory performance in older adults
Chronic administration of Tat-GluR23Y ameliorates cognitive dysfunction targeting CREB signaling in rats with amyloid beta neurotoxicity
The effects of betulinic acid on neurobehavioral activity, electrophysiology and histological changes in an animal model of the Alzheimerโs disease
Arctigenin attenuates ischemic stroke via SIRT1-dependent inhibition of NLRP3 inflammasome
Arctigenin attenuates learning and memory deficits through PI3k/Akt/GSK-3ฮฒ pathway reducing tau hyperphosphorylation in Aฮฒ-induced AD mice
Lactobacilli-fermented cowโs milk attenuated lipopolysaccharide-induced neuroinflammation and memory impairment in vitro and in vivo
Kaempferol attenuates cognitive deficit via regulating oxidative stress and neuroinflammation in an ovariectomized rat model of sporadic dementia
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid ฮฒ production and clearance
Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampalย โฆ
Astaxanthin improved the cognitive deficits in APP/PS1 transgenic mice via selective activation of mTOR
A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimerโs disease
N-acetyl cysteine supplementation prevents impairment of spatial working memory functions in rats following exposure to hypobaric hypoxia
Targeted inhibition of RAGE reduces amyloid-ฮฒ influx across the blood-brain barrier and improves cognitive deficits in db/db mice
Isoorientin improves scopolamine-induced cognitive impairments by restoring the cholinergic system, antioxidant defense, and p-CREB/BDNF signaling in theย โฆ
HSF1/HSP pathway in the hippocampus is involved in SIRT1-mediated caloric restriction-induced neuroprotection after surgery in aged mice
Amyloid-ฮฒ causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons
Neuroprotective effects of salidroside administration in a mouse model of Alzheimerโs disease
Intraperitoneal administration of a novel TAT-BDNF peptide ameliorates cognitive impairments via modulating multiple pathways in two Alzheimerโs rodentย โฆ
Neuroprotective effects of berberine in animal models of Alzheimerโs disease: a systematic review of pre-clinical studies
Ghrelin-mediated hippocampal neurogenesis: implications for health and disease
Lactobacillus fermentum ZS40 Ameliorates Inflammation in Mice With Ulcerative Colitis Induced by Dextran Sulfate Sodium
Cognitive dysfunctions induced by a cholinergic blockade and Aฮฒ25โ35 peptide are attenuated by salvianolic acid B
Ameliorating effect of luteolin on memory impairment in an Alzheimerโs disease model
Lactobacillus sakei OK67 ameliorates collagen-induced arthritis in mice by inhibiting NF-ฮบB activation and restoring Th17/Treg cell balance
Quercetin reverses hypobaric hypoxia-induced hippocampal neurodegeneration and improves memory function in the rat
The molecular implications of a caspase-2-mediated site-specific tau cleavage in tauopathies
rTMS Ameliorates Prenatal StressโInduced Cognitive Deficits in Male-Offspring Rats Associated With BDNF/TrkB Signaling Pathway
Tadalafil crosses the bloodโbrain barrier and reverses cognitive dysfunction in a mouse model of AD
Prophylactic melatonin treatment ameliorated Propofol-Induced cognitive dysfunction in aged rats
Recent insights into the biological activities and drug delivery systems of tanshinones
CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice
Amentoflavone Ameliorates Aฮฒ1โ42-Induced Memory Deficits and Oxidative Stress in Cellular and Rat Model
The effect of fish oil on social interaction memory in total sleep-deprived rats with respect to the hippocampal level of stathmin, TFEB, synaptophysin and LAMP-1ย โฆ
Donepezil inhibits the amyloid-beta oligomer-induced microglial activation in vitro and in vivo
Plant natural products for cognitive impairment: A review of the preclinical evidence
Calmodulinโlike skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease
Natural products targeting amyloid beta in Alzheimerโs disease
Protective effect of atorvastatin on d-galactose-induced aging model in mice
Effects of extracts from Cordyceps sinensis on M1 muscarinic acetylcholine receptor in vitro and in vivo
Saponins from Panax japonicus attenuate D-galactose-induced cognitive impairment through its anti-oxidative and anti-apoptotic effects in rats
Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimerโs disease
Theaflavins improve memory impairment and depression-like behavior by regulating microglial activation
Simvastatin ameliorate memory deficits and inflammation in clinical and mouse model of Alzheimerโs disease via modulating the expression of miR-106b
Phosphodiesterase inhibition in cognitive decline
Cornel iridoid glycoside induces autophagy to protect against tau oligomer neurotoxicity induced by the activation of glycogen synthase kinase-3ฮฒ
Therapeutic effect of organoselenium dietary supplementation in a sporadic dementia of Alzheimerโs type model in rats
Suppression of adiponectin receptor 1 promotes memory dysfunction and Alzheimerโs disease-like pathologies
Lycopene-a pleiotropic neuroprotective nutraceutical: deciphering its therapeutic potentials in broad spectrum neurological disorders
Neuroinflammatory response to experimental stroke is inhibited by eriodictyol
Prebiotic Effect of Fructooligosaccharides from Morinda officinalis on Alzheimerโs Disease in Rodent Models by Targeting the Microbiota-Gut-Brain Axis
Lactobacillus paracasei PS23 dietary supplementation alleviates muscle aging via ghrelin stimulation in d-galactose-induced aging mice
The transcription factor Sp3 cooperates with HDAC2 to regulate synaptic function and plasticity in neurons
Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aฮฒ25โ35 or Aฮฒ1โ40 peptide in rats
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on spatial memory and on cholinergic and peptidergic neurons in rats with ibotenate-induced lesions of theย โฆ
Physical exercise prevents motor disorders and striatal oxidative imbalance after cerebral ischemia-reperfusion
A dual inhibitor of the proteasome catalytic subunits LMP2 and Y attenuates disease progression in mouse models of Alzheimerโs disease
Berberine neuroprotection and antioxidant activity
The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice
NEURAL EFFECTS OF THE PROLACTIN/VASOINHIBIN AXIS
The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): Oversight for neurodegenerative disorders
Influence of Asafoetida on Prevention and Treatment of Memory Impairment Induced by d-Galactose and NaNO2 in Mice
Phosphodiesterase: an interface connecting cognitive deficits to neuropsychiatric and neurodegenerative diseases
The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction
Ameliorative effects of apple cider vinegar on neurological complications via regulation of oxidative stress markers
Semaglutide-mediated protection against Aฮฒ correlated with enhancement of autophagy and inhibition of apotosis
Alpha-tocopherol in the brain tissue preservation of stroke-prone spontaneously hypertensive rats
Impact of interval training with probiotic (L. plantarum/Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimerโsย โฆ
A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimerโs disease
Amyrin attenuates scopolamine-induced cognitive impairment in mice
Neuroprotective effect of ligustilide through induction of ฮฑ-secretase processing of both APP and Klotho in a mouse model of Alzheimerโs disease
Probiotic mixture KF attenuates age-dependent memory deficit and lipidemia in Fischer 344 rats
Sulfated polysaccharide isolated from the nacre of pearl oyster improves scopolamine-induced memory impairment
Nobiletin protects dopaminergic neurons in the 1-methyl-4-phenylpyridinium-treated rat model of Parkinsonโs disease
H2S Attenuates Sleep Deprivation-Induced Cognitive Impairment by Reducing Excessive Autophagy via Hippocampal Sirt-1 in WISTAR RATS
Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: Behavioral and ultrastructural approaches
Amyloid-ฮฒ peptide impact on synaptic function and neuroepigenetic gene control reveal new therapeutic strategies for Alzheimerโs disease
A recent overview on the biological and pharmacological activities of ferulic acid
Oroxylin A improves attention deficit hyperactivity disorder-like behaviors in the spontaneously hypertensive rat and inhibits reuptake of dopamine in vitro
Fisetin enhances behavioral performances and attenuates reactive gliosis and inflammation during aluminum chloride-induced neurotoxicity
Optimized-SopungSunkiwon, a Herbal Formula, Attenuates Aฮฒ Oligomer-Induced Neurotoxicity in Alzheimerโs Disease Models
Sesamin alleviates diabetes-associated behavioral deficits in rats: The role of inflammatory and neurotrophic factors
Synaptic and Memory Dysfunction Induced by Tau Oligomers is Rescued by Up-regulation of the Nitric Oxide Cascade
Memory Impairment in A?'(25-35) and D-Galactose Induced Alzheimerโs Disease Model Rat
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimerโs disease mouse model
Sildenafil protects neuronal cells from mitochondrial toxicity induced by ฮฒ-amyloid peptide via ATP-sensitive K+ channels
In vitro antioxidant activities of proanthocyanidins extracted from the lotus seedpod and ameliorative effects on learning and memory impairment in scopolamineย โฆ
Tanshinone IIA attenuates Aฮฒ25โ35-induced spatial memory impairment via upregulating receptors for activated C kinase1 and inhibiting autophagy in hippocampus
Neuroprotective effect of forsythiaside against transient cerebral global ischemia in gerbil
Voluntary wheel running improves spatial learning memory by suppressing inflammation and apoptosis via inactivation of nuclear factor kappa B in brainย โฆ
Natural products as modulators of the proteostasis machinery: implications in neurodegenerative diseases
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy
An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by ฮฒ-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChRย โฆ
Probiotic Lactobacillus fermentum strain JDFM216 improves cognitive behavior and modulates immune response with gut microbiota
Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: indications for central and peripheral mechanisms
Amentoflavone suppresses amyloid ฮฒ1โ42 neurotoxicity in Alzheimerโs disease through the inhibition of pyroptosis
Ellagic acid protects against diabetes-associated behavioral deficits in rats: Possible involved mechanisms
Effects and mechanisms of natural products on Alzheimerโs disease
Traditional Korean East Asian medicines and herbal formulations for cognitive impairment
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: roles of PERK/eIF2ฮฑ signaling pathway
Lactobacillus sakei OK67 ameliorates high-fat dietโinduced blood glucose intolerance and obesity in mice by inhibiting gut microbiota lipopolysaccharide productionย โฆ
PNU282987 alleviates Aฮฒ-induced anxiety and depressive-like behaviors through upregulation of ฮฑ7nAChR by ERK-serotonin receptors pathway
Pulmonary B cells ameliorate Alzheimerโs disease-like neuropathology
Goat milk attenuates mimetic aging related memory impairment via suppressing brain oxidative stress, neurodegeneration and modulating neurotrophic factors in dย โฆ
Valproic acid alleviates memory deficits and attenuates amyloid-ฮฒ deposition in transgenic mouse model of Alzheimerโs disease
Anti-aging effect of the combination of Bifidobacterium longum and B. animalis in a d-galactose-treated mice
Atorvastatin ameliorates depressive behaviors and neuroinflammatory in streptozotocin-induced diabetic mice
Effect of delta opioid receptor activation on spatial cognition and neurogenesis in cerebral ischemic rats
Polysaccharides from Tetrastigma hemsleyanum Diels et Gilg: extraction optimization, structural characterizations, antioxidant and antihyperlipidemic activities inย โฆ
Dinitrobenzene sulphonic acid-induced colitis impairs spatial recognition memory in mice: roles of N-methyl D-aspartate receptors and nitric oxide
Whole body vibration training improves depression-like behaviors in a rat chronic restraint stress model
Natural products as a source of Alzheimerโs drug leads
Roles of multiple lipid mediators in stress and depression
Traditional Chinese medicine-based neurorestorative therapy for Alzheimerโs and Parkinsonโs disease
Danshen diversity defeating dementia
Green tea polyphenols improve isoflurane-induced cognitive impairment via modulating oxidative stress
Flavonoid-rich ethanol extract from the leaves of Diospyros kaki attenuates cognitive deficits, amyloid-beta production, oxidative stress, and neuroinflammation in APPย โฆ
Metabolic profiling of the effects of ginsenoside Re in an Alzheimerโs disease mouse model
Cognitive-enhancing herbal formulae in Korean medicine: identification of candidates by text mining and literature review
Treadmill exercise enhances motor coordination and ameliorates Purkinje cell loss through inhibition on astrocyte activation in the cerebellum of methimazoleย โฆ
Protein hydrolysate of silkworm pupa prevents memory impairment induced by oxidative stress in scopolamine-induced mice via modulating the cholinergicย โฆ
ERK activation by zeranol has neuroprotective effect in cerebral ischemia reperfusion
An optimized combination of ginger and peony root effectively inhibits amyloid-ฮฒ accumulation and amyloid-ฮฒ-mediated pathology in AฮฒPP/PS1 double-transgenicย โฆ
Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders
Notopterygium incisum extract (NRE) rescues cognitive deficits in APP/PS1 Alzhneimerโs disease mice by attenuating amyloid-beta, tau, and neuroinflammationย โฆ
Fingolimod limits acute Aฮฒ neurotoxicity and promotes synaptic versus extrasynaptic NMDA receptor functionality in hippocampal neurons
Preadministration of high-dose alpha-tocopherol improved memory impairment and mitochondrial dysfunction induced by proteasome inhibition in rat hippocampus
Dl-3-n-butylphthalide regulates cholinergic dysfunction in chronic cerebral hypoperfusion rats
Targeting the JAK2/STAT3 axis in Alzheimerโs disease
Potential effects of current drug therapies on cognitive impairment in patients with type 2 diabetes
Neuroprotective effects of berberine in animal models of Alzheimerโs disease: a systematic review of pre-clinical studies
Gastrodin attenuates bilateral common carotid artery occlusion-induced cognitive deficits via regulating Aฮฒ-related proteins and reducing autophagy andย โฆ
Lactobacillus brevis OK56 ameliorates high-fat diet-induced obesity in mice by inhibiting NF-ฮบB activation and gut microbial LPS production
Dysfunctional autophagy and endolysosomal system in neurodegenerative diseases: relevance and therapeutic options
The Protective Effects of Gardenia jasminoides (Fructus Gardenia) on Amyloid-ฮฒ-Induced Mouse Cognitive Impairment and Neurotoxicity
The memory-enhancing effects of 7, 8, 4โฒ-trihydroxyisoflavone, a major metabolite of daidzein, are associated with activation of the cholinergic system and BDNFย โฆ
Alzheimersโ disease and epilepsy: a literature review
Royal jelly alleviates cognitive deficits and ฮฒ-amyloid accumulation in APP/PS1 mouse model via activation of the cAMP/PKA/CREB/BDNF pathway andย โฆ
Extensive intestinal first-pass metabolism of arctigenin: evidenced by simultaneous monitoring of both parent drug and its major metabolites
Quercetin ameliorate oxidative/nitrosative stress in the brain of rats exposed to intermittent hypobaric hypoxia
A novel prolyl endopeptidase inhibitor, JTP-4819-its behavioral and neurochemical properties for the treatment of Alzheimerโs disease
Journal of Molecular Biomarkers & Diagnosis
Danggui-Shaoyao-San (DSS) ameliorates cerebral ischemia-reperfusion injury via activating SIRT1 signaling and inhibiting NADPH oxidases
Tadalafil enhances working memory, and reduces hippocampal oxidative stress in both young and aged mice
Peripheral nerve injury leads to working memory deficits and dysfunction of the hippocampus by upregulation of TNF-ฮฑ in rodents
5-Aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating Alzheimerโs disease phenotypes
Gut microbiome and behavior: focus on neuroimmune interactions
Phosphorylation and antiaging activity of polysaccharide from Trichosanthes peel
Effects of putative cognitive function-enhancing drugs and dopaminergic agents on somatostatin and neuropeptide Y in rat brain
Platycodon grandiflorus Root Extract Improves Learning and Memory by Enhancing Synaptogenesis in Mice Hippocampus
Wheat embryo globulin nutrients ameliorate d-galactose and aluminum chloride-induced cognitive impairment in rats
Berberine chloride improved synaptic plasticity in STZ induced diabetic rats
Berberine attenuates convulsing behavior and extracellular glutamate and aspartate changes in 4-aminopyridine treated rats
Anti-Alzheimer properties of probiotic, Lactobacillus plantarum MTCC 1325 in Alzheimerโs disease induced albino rats
Role of berberine in Alzheimerโs disease
Heat shock protein signaling in brain ischemia and injury
Humanin and the receptors for humanin
Effect of glycyrrhizic acid on scopolamine-induced cognitive impairment in mice
Resveratrol in Alzheimerโs disease: a review of pathophysiology and therapeutic potential
Protective effect of exercise and sildenafil on acute stress and cognitive function
Modulation of hippocampal TLR4/BDNF signal pathway using probiotics is a step closer towards treating cognitive impairment in NASH model
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimerโs disease animal model: A systematic review
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1
Evaluation of anti-amnesic effect of extracts of selected Ocimum species using in-vitro and in-vivo models
Protective effects of Humanin and calmodulin-like skin protein in Alzheimerโs disease and broad range of abnormalities
Pulmonary B Lymphocytes Ameliorate Alzheimerโs Disease-Like Neuropathology
Ameliorative effects of a cognitive enhancer, T-588, on place learning deficits induced by transient forebrain ischemia in rats
Female-dependent impaired fear memory of adult rats induced by maternal separation, and screening of possible related genes in the hippocampal CA1
Effects of Piperine Pretreatment on Antioxidant Capacity and Spatial Memory Impairment Induced by Local Injection of Lysolecethin in Rat Hippocampus
Modulation of hippocampal dopamine and synapse-related proteins by electroacupuncture improves memory deficit caused by sleep deprivation
A Status Report on Autonomic Nervous System: The Indian Research Scenario During the Last Five Years
The inhibitory effect of chitosan oligosaccharides on ฮฒ-site amyloid precursor protein cleaving enzyme 1 (BACE1) in HEK293 APPswe cells
Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice
Tadalafil versus linaclotide in gastrointestinal dysfunction and depressive behavior in constipationโpredominant irritable bowel syndrome
Preventive action of Kai Xin San aqueous extract on depressive-like symptoms and cognition deficit induced by chronic mild stress
Cognitive enhancing effect of diapocynin in D-galactose-ovariectomy-induced Alzheimerโs-like disease in rats: Role of ERK, GSK-3ฮฒ, and JNK signaling
Gut flora-targeted photobiomodulation therapy improves senile dementia in an Aร-induced Alzheimerโs disease animal model
Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy
Effect of Wuling powder on the pharmacokinetics of valproic acid in epileptic rats
Flavonoids with potential anti-amyloidogenic effects as therapeutic drugs for treating Alzheimerโs disease
Echinacoside suppresses amyloidogenesis and modulates F-actin remodeling by targeting the ER stress sensor PERK in a mouse model of Alzheimerโsย โฆ
Differential expression levels of the hippocampal ghrelin and its receptor mRNA during memory consolidation
PERK as a hub of multiple pathogenic pathways leading to memory deficits and neurodegeneration in Alzheimerโs disease
Enteromorpha prolifera Extract Improves Memory in Scopolamine-Treated Mice via Downregulating Amyloid-ฮฒ Expression and Upregulating BDNF/TrkB Pathway
Protective effect of low dose caffeine on psychological stress and cognitive function
Tanshinone I alleviates motor and cognitive impairments via suppressing oxidative stress in the neonatal rats after hypoxic-ischemic brain damage
Traditional oriental medicines and Alzheimerโs disease
Muscarinic agonists for the treatment of cognition in schizophrenia
The protective effect of zeranol in cerebral ischemia reperfusion via p-CREB overexpression
Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimerโs disease mice by modulating propionic acid levels, glycogen synthase kinase 3ย โฆ
Hesperetin confers neuroprotection by regulating Nrf2/TLR4/NF-ฮบB signaling in an Aฮฒ mouse model
Protective role of apigenin against Aฮฒ 25โ35 toxicity via inhibition of mitochondrial cytochrome c release
Efficacy and safety of traditional Chinese medicine on thromboembolic events in patients with atrial fibrillation: a systematic review and meta-analysis
Fyn deficiency attenuates renal fibrosis by inhibition of phospho-STAT3
Potential enzymatic targets in Alzheimerโs: a comprehensive review
Ethanol extract of the seed of Zizyphus jujuba var. spinosa potentiates hippocampal synaptic transmission through mitogen-activated protein kinase, adenylyl cyclaseย โฆ
A microRNA signature that correlates with cognition and is a target against cognitive decline
Selective targeting of non-nuclear estrogen receptors with PaPE-1 as a new treatment strategy for Alzheimerโs disease
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKฮฒ/AMPK pathways
A novel strain of Lactobacillus mucosae isolated from a Gaotian villager improves in vitro and in vivo antioxidant as well as biological properties in d-galactoseย โฆ
The impact of vitamin E and other fat-soluble vitamins on Alzheimer s disease
Tripchlorolide may improve spatial cognition dysfunction and synaptic plasticity after chronic cerebral hypoperfusion
Antidiabetic polypill improves central pathology and cognitive impairment in a mixed model of Alzheimerโs disease and type 2 diabetes
Green tea epigallocatechin-3-gallate (EGCG) targeting protein misfolding in drug discovery for neurodegenerative diseases
Dried plum and chokeberry ameliorate d-galactose-induced aging in mice by regulation of Pl3k/Akt-mediated Nrf2 and Nf-kB pathways
Prevention of the brain neurodegeneration in rats with experimental Alzheimerโs disease by adaptation to hypoxia
An 8-Week Administration of Bifidobacterium bifidum and Lactobacillus plantarum Combined with Exercise Training Alleviates Neurotoxicity of Aฮฒ and Spatialย โฆ
Probiotics for preventing cognitive impairment in Alzheimerโs disease
Effective suppression of nitric oxide production by HX106N through transcriptional control of heme oxygenase-1
Inconsistent effects of sleep deprivation on memory function
In vitro binding and in vivo biodistribution studies of the neuroprotective peptide humanin using [125I] humanin derivatives
Glaucocalyxin A as a natural product increases amyloid ฮฒ clearance and decreases tau phosphorylation involving the mammalian target of rapamycin signalingย โฆ
Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice
Therapeutic Efficacy of Fenugreek Extract or/and Choline with Docosahexaenoic Acid in Attenuating Learning and Memory Deficits in Ovariectomized Rats.
Simvastatin attenuates hippocampal MMP-9 expression in the streptozotocin-induced cognitive impairment
Tanshinone I selectively suppresses pro-inflammatory genes expression in activated microglia and prevents nigrostriatal dopaminergic neurodegeneration in a mouseย โฆ
The effects of Nigella sativa on neural damage after pentylenetetrazole induced seizures in rats
Ferulate, an active component of wheat germ, ameliorates oxidative stress-induced PTK/PTP imbalance and PP2A inactivation
Protective effects of ginsenosides Rg1 and Rb1 on an Alzheimerโs disease mouse model: A metabolomics study
Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
Ginger improves cognitive function via NGF-induced ERK/CREB activation in the hippocampus of the mouse
Neurosteroids in depression: a review
The mTOR Signaling Pathway in Neurodegenerative Diseases
Hippocampal CysLT1R overexpression or activation accelerates memory deficits, synaptic dysfunction, and amyloidogenesis in young APP/PS1 transgenicย โฆ
New perspectives of Lactobacillus plantarum as a probiotic: The gut-heart-brain axis
Autophagy and neurodegeneration
Probiotics: An Adjuvant therapy for D-Galactose induced Alzheimerโs disease
Natural phytochemicals in the treatment and prevention of dementia: An overview
Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis
Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy metabolism andย โฆ
Ghrelin attenuates depressive-like behavior, heart failure, and neuroinflammation in postmyocardial infarction rat model
Melatonin improves cognitive deficits via restoration of cholinergic dysfunction in a mouse model of scopolamine-induced amnesia
The antioxidant effects of whey protein peptide on learning and memory improvement in aging mice models
Investigating the effect of ghrelin on improving memory and learning ability in animals: A systematic review
Unifi nootropics from the lab to the web: a story of academic (and industrial) shortcomings
Alterations in the CNS effects of anti-epileptic drugs by Chinese herbal medicines
The role of G protein-coupled estrogen receptor 1 on neurological disorders
Hydroalcoholic extract from Abelmoschus manihot (Linn.) Medicus flower reverses sleep deprivation-evoked learning and memory deficit
Neuraminidase-inhibition Activity of Nodakenetin from Gongjin-dan Fermented by Lactic Acid Bacteria
Antiaging therapies, cognitive impairment, and dementia
Effects of dietary glucocerebrosides from sea cucumber on the brain sphingolipid profiles of mouse models of Alzheimerโs disease
Investigating the effect of crocin on memory deficits induced by total sleep deprivation (TSD) with respect to the BDNF, TrkB and ERK levels in the hippocampus ofย โฆ
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
Soursop fruit extract mitigates scopolamine-induced amnesia and oxidative stress via activating cholinergic and Nrf2/HO-1 pathways
Tanshinone IIA alleviates CCL2-induced leaning memory and cognition impairment in rats: A potential therapeutic approach for HIV-associatedย โฆ
Sphingolipids in foodstuff: Compositions, distribution, digestion, metabolism and health effectsโA comprehensive review
New insights into the pathogenesis of Alzheimerโs disease
A novel rat model of fatty organ degeneration induced by poloxamer 407
New Results on the Pharmacology and Clinical Use of the TCM-Drug Salvia miltiorrhiza
Euxanthone Attenuates Aฮฒ1โ42-Induced Oxidative Stress and Apoptosis by Triggering Autophagy
Vascular endothelial growth factor improves the cognitive decline of Alzheimerโs disease via concurrently inducing the expression of ADAM10 and reducing theย โฆ
miR-124 downregulates BACE 1 and alters autophagy in APP/PS1 transgenic mice
Quercetin regulates the integrated stress response to improve memory
The role of amygdala-based caspase-1 activation in regulating the behavioral response to allostatic stress
Emerging potential of naturally occurring autophagy modulators against neurodegeneration
Driving neural regeneration through the mammalian target of rapamycin
Adverse maternal environment alters microRNA-10b-5p expression and its epigenetic profile concurrently with impaired hippocampal neurogenesis in maleย โฆ
Treadmill exercise improves motor function and short-term memory by enhancing synaptic plasticity and neurogenesis in photothrombotic stroke mice
Poria cocos polysaccharide attenuates damage of nervus in Alzheimerโs disease rat model induced by D-galactose and aluminum trichloride
Icariside II effectively reduces spatial learning and memory impairments in Alzheimerโs disease model mice targeting beta-amyloid production
Receptor-interacting protein kinase 1 (RIPK1) as a potential therapeutic target: an overview of its possible role in the pathogenesis of Alzheimerโs disease
Role of D-galactose-induced brain aging and its potential used for therapeutic interventions
Neuro-nutrients as anti-alzheimerโs disease agents: A critical review
Disrupted hippocampal growth hormone secretagogue receptor 1ฮฑ interaction with dopamine receptor D1 plays a role in Alzheimerโฒ s disease
Roles of eIF2ฮฑ kinases in the pathogenesis of Alzheimerโs disease
Suan-Zao-Ren Decoction Ameliorate Synaptic Plasticity Through the Inhibition of JAK2/STAT3 Signaling Pathway in APP/PS1 Transgenic Mice
Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseases
Therapy of Dredging the Bowels Enhanced the Neuroprotective Effect of Nourishing Kidney Herbs on Hippocampal Cholinergic System in Alzheimerโsย โฆ
Isolation and characterization of marker compounds from the leaves of allium cepa linn. and study of their biological activities
DW14006 as a direct AMPKฮฑ1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
Role of flavonoids in neurodegenerative diseases: Limitations and future perspectives
Fecal microbiota transplantation alleviated Alzheimerโs disease-like pathogenesis in APP/PS1 transgenic mice
Aberrant complement system activation in neurological disorders
Longevity pathways (mTOR, SIRT, Insulin/IGF-1) as key modulatory targets on aging and neurodegeneration
Notoginsenoside R1 improves cerebral ischemia/reperfusion injury by promoting neurogenesis via the BDNF/Akt/CREB pathway
Angelica Sinensis Extract Protects Against Memory Deficits by Promoting P38 MAPKโmediated Hippocampal Neurogenesis and Neuronal Survival in theย โฆ
Icariin, a major constituent of flavonoids from Epimedium brevicornum, protects against cognitive deficits induced by chronic brain hypoperfusion via its antiย โฆ
Reconstituted mother tinctures of Gelsemium sempervirens L. improve memory and cognitive impairment in mice scopolamine-induced dementia model
Sleep deprivation induces cognitive impairment by increasing blood-brain barrier permeability via CD44
Peptide therapeutics in neurodegenerative disorders
Neurotrophic peptides: potential drugs for treatment of amyotrophic lateral sclerosis and Alzheimerโs disease
Wogonin increases ฮฒ-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimerโs disease
Acupuncture accelerates neural regeneration and synaptophysin production after neural stem cells transplantation in mice
Saffron and neurological disorders
Humanin; a defender against Alzheimerโs disease?
Alzheimerโs disease animal models: elucidation of biomarkers and therapeutic approaches for cognitive impairment
Alterations in brain-derived neurotrophic factor in the mouse hippocampus following acute but not repeated benzodiazepine treatment
Natural products as modulator of autophagy with potential clinical prospects
The protective effect of vanadium on cognitive impairment and the neuropathology of Alzheimerโs disease in APPSwe/PS1dE9 mice
Gastric floating pill enhances the bioavailability and drug efficacy of dihydromyricetin in vivo
Tanshinone IIA Alleviates CCL2-Induced Leaning memory and Cognition Impairment in Rats: A Potential Therapeutic Approach for HIV-Associated Neurocognitiveย โฆ
Ghrelin in Alzheimerโs disease: pathologic roles and therapeutic implications
The potential of flavonoids for the treatment of neurodegenerative diseases
Natural compounds with anti-BACE1 activity as promising therapeutic drugs for treating Alzheimerสผs disease
The Neuroprotective Effects of Moderate Treadmill Exercise in a Rat Model of Alzheimerโs Disease
Activation of ฮฑ7 nicotinic acetylcholine receptor alleviates Aฮฒ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways
Mulberry fruit prevents diabetes and diabetic dementia by regulation of blood glucose through upregulation of antioxidative activities and CREB/BDNFย โฆ
Neuroprotective effect of Chunghyuldan from amyloid beta oligomer induced neuroinflammation in vitro and in vivo
Diazepam and SL-327 synergistically attenuate anxiety-like behaviours in miceโPossible hippocampal MAPKs specificity
Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPKโmediated hippocampal neurogenesis and dendritic growth in the chronic phase ofย โฆ
Neuroprotective natural products for Alzheimerโs disease
Nicotine Modulates Cognitive Function in D-Galactose-Induced Senescence in Mice
Differential change in cortical and hippocampal monoamines, and behavioral patterns in streptozotocin-induced type 1 diabetic rats
Chrysophanol improves memory ability of d-galactose and Aฮฒ25โ35 treated rat correlating with inhibiting tau hyperphosphorylation and the CaMโCaMKIV signalย โฆ
Antioxidant and antimicrobial profile of chicken sausages prepared after fermentation of minced chicken meat with Lactobacillus plantarum and with additionalย โฆ
Aฮฒ peptide secretion is reduced by Radix Polygalaeโinduced autophagy via activation of the AMPK/mTOR pathway
RETRACTED: Swimming exercise increases the level of nerve growth factor and stimulates neurogenesis in adult rat hippocampus
Pyridoxine exerts antioxidant effects in cell model of Alzheimerโs disease via the Nrf-2/HO-1 pathway
Ellagic acid: insights into its neuroprotective and cognitive enhancement effects in sporadic Alzheimerโs disease
The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models
mTOR: Driving apoptosis and autophagy for neurocardiac complications of diabetes mellitus
Resistance exercise improves short-term memory through inactivation of NF-ฮบB pathway in mice with Parkinson disease
5, 7-Dihydroxy-6-methoxy-4โฒ-phenoxyflavone, a derivative of oroxylin A improves attention-deficit/hyperactivity disorder (ADHD)-like behaviors in spontaneouslyย โฆ
S100A8/A9 drives neuroinflammatory priming and protects against anxiety-like behavior after sepsis
Brain food for Alzheimer-free ageing: focus on herbal medicines
Physical exercise during pregnancy prevents cognitive impairment induced by amyloid-ฮฒ in adult offspring rats
Autophagic activity in neuronal cell death
Natural compound loaded nanoparticles for effective treatment of Alzheimerโs disease-A review
Modulation of the MAPKs pathways affects Aฮฒ-induced cognitive deficits in Alzheimerโs disease via activation of ฮฑ7nAChR
Quercetin exhibits ฮฑ7nAChR/Nrf2/HO-1-mediated neuroprotection against STZ-induced mitochondrial toxicity and cognitive impairments in experimental rodents
The antidepressant-like effects of Danggui Buxue Decoction in GK rats by activating CREB/BDNF/TrkB signaling pathway
Inhibition of heat shock protein 90 by 17-AAG reduces inflammation via P2X7 receptor/NLRP3 inflammasome pathway and increases neurogenesis afterย โฆ
Autophagy in Alzheimerโs disease
Phytoconstituents and their Possible Mechanistic Profile for Alzheimerโs DiseaseโA Literature Review
Aฮฒ regulation-based multitarget strategy for drug discovery against Alzheimerโs disease
Hypothyroidism induces interleukin-1-dependent autophagy mechanism as a key mediator of hippocampal neuronal apoptosis and cognitive decline in postnatal rats
Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L
Gerobiotics: probiotics targeting fundamental aging processes
Dexmedetomidine Attenuates Hippocampal Damage and Improves Cognition by Up-Regulating Glyoxalase1 in APP/PS1 Mice
Macrophage polarization induced by probiotic bacteria: a concise review
Dexpramipexole enhances hippocampal synaptic plasticity and memory in the rat
Hops extract alleviates Aฮฒ-injury to osteoblasts through antioxidant pathway
An open-label, single-arm pilot study to evaluate the efficacy of daily low dose tadalafil on depression in patients with erectile dysfunction
Beneficial Effects of Epigallocatechin-3-O-Gallate, Chlorogenic Acid, Resveratrol, and Curcumin on Neurodegenerative Diseases
Novel phosphodiesterase type 5 modulators: a patent survey (2008โ2010)
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein
The Protective Effects of Acer okamotoanum and Isoquercitrin on Obesity and Amyloidosis in a Mouse Model
The molecular mechanisms of signal pathway activating effect of E2F-1/NF-ฮบB/GSK-3ฮฒ on cognitive dysfunction of Alzheimer rats
Amyloid precursor protein regulates 5-fluorouracil resistance in human hepatocellular carcinoma cells by inhibiting the mitochondrial apoptotic pathway
Effects of denial of reward through maternal contact in the neonatal period on adult hypothalamicโpituitaryโadrenal axis function in the rat
Whatโs new about crop plants: novel discoveries of the 21st century
Arctigenin increases hemeoxygenase-1 gene expression by modulating PI3K/AKT signaling pathway in rat primary astrocytes
Effect of amyloid toxicity or chronic cerebral hypoperfusion on brain insulin resistance in a rat model with intracerebroventricular streptozotocin
Medicinal plants possessed beneficial therapeutic effects in Alzheimerโs disease and memory deficits
In-vitro importance of probiotic Lactobacillus plantarum related to medical field 2
Hesperetin rescues emotional memory and synaptic plasticity deficit in aged rats.
Transient bilateral common carotid artery occlusion (tBCCAO) of rats as a model of global cerebral ischemia
The effects of Bisphenol-A, Zearalenoneand Arsenic on specific brain areas
Protective effect of arctigenin on ethanol-induced neurotoxicity in PC12 cells
[Gly14]-Humanin reduces histopathology and improves functional outcome after traumatic brain injury in mice
NT-020, a natural therapeutic approach to optimize spatial memory performance and increase neural progenitor cell proliferation and decrease inflammation in theย โฆ
Oxymatrine attenuates diabetes-associated cognitive deficits in rats
Fluoxetine attenuated anxiety-like behaviors in streptozotocin-induced diabetic mice by mitigating the inflammation
Chronic cerebral hypoperfusion induces vascular plasticity and hemodynamics but also neuronal degeneration and cognitive impairment
miRโ134โ5p/Foxp2/Syn1 is involved in cognitive impairment in an early vascular dementia rat model
Thymoquinone attenuates brain injury via an antioxidative pathway in a status epilepticus rat model
Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouse
Aqua-soluble DDQ reduces the levels of Drp1 and A ฮฒ and inhibits abnormal interactions between A ฮฒ and Drp1 and protects Alzheimerโs disease neurons from A ฮฒย โฆ
Insulin signaling pathway and related molecules: role in neurodegeneration and Alzheimerโs disease
Association of tea consumption with risk of Alzheimerโs disease and anti-beta-amyloid effects of tea
Antioxidant, Anti-inflammatory and Anticholinergic action of berberine attenuates diabetic encephalopathy: Behavioral and Biochemical evidences
Nanomedicine strategies for sustained, controlled and targeted treatment of Alzheimerโs disease
Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor ฮฑ/WSX-1/gp130
Saikosaponin-d-mediated downregulation of neurogenesis results in cognitive dysfunction by inhibiting Akt/Foxg-1 pathway in mice
Dexmedetomidine alleviates lipopolysaccharide-induced hippocampal neuronal apoptosis via inhibiting the p38 MAPK/c-Myc/CLIC4 signaling pathway in rats
Molecular insight into the therapeutic promise of flavonoids against Alzheimerโs disease
Atorvastatin modulates the expression of aging-related genes in the brain of aging induced by D-galactose in mice
Signaling pathway cross talk in Alzheimerโs disease
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram)
Recent progress in the role of autophagy in neurological diseases
Elucidation of arctigenin pharmacokinetics and tissue distribution after intravenous, oral, hypodermic and sublingual administration in rats and beagle dogsย โฆ
The green tea polyphenolic catechin epigallocatechin gallate and neuroprotection
The pharmacological activities of licorice
Berberine improves behavioral and cognitive deficits in a mouse model of alzheimerโs disease via regulation of ฮฒ-amyloid production and endoplasmic reticulumย โฆ
Hippocampal extracellular signal-regulated kinase signaling has a role in passive avoidance memory retrieval induced by GABAA receptor modulation inย โฆ
Valproic acid attenuates bloodโbrain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition
The effect of agomelatine treatment on diabetes-induced cognitive impairments in rats: concomitant alterations in the hippocampal neuron numbers
The role of autophagy in Alzheimerโs disease and its potential for therapy
Fluoxetine abolished psychological stress deleterious effect on memory in protein malnourished mice
The neurocognitive effects of Ghrelin-induced signaling on the hippocampus: a promising approach to Alzheimerโs disease
Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba)
miRโ132 improves the cognitive function of rats with Alzheimerโs disease by inhibiting the MAPK1 signal pathway
Chalcone-derived Nrf2 activator protects cognitive function via maintaining neuronal redox status
Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinsonโs disease
Autophagy is involved in oral rAAV/Aฮฒ vaccine-induced Aฮฒ clearance in APP/PS1 transgenic mice
Preventive effect of Coriandrum sativum on neuronal damages in pentylentetrazole-induced seizure in rats
Effects of lacosamide treatment on epileptogenesis, neuronal damage and behavioral comorbidities in a rat model of temporal lobe epilepsy
Polydeoxyribonucleotide attenuates airway inflammation through A2AR signaling pathway in PM10-exposed mice
Characterization and preparation of oligomeric procyanidins from Litchi chinensis pericarp
Role of Lactobacillus plantarum MTCC1325 in membrane-bound transport ATPases system in Alzheimerโs disease-induced rat brain
Antioxidant potential of curcuminโA meta-analysis of randomized clinical trials
17-Allylamino-demethoxygeldanamycin ameliorate microthrombosis via HSP90/RIP3/NLRP3 pathway after subarachnoid hemorrhage in rats
Ctotoxic and apoptogenic effects of Perovskia abrotanoides flower extract on MCF-7 and HeLa cell lines
Effect of berberine chloride on caspase-3 dependent apoptosis and antioxidant capacity in the hippocampus of the chronic cerebral hypoperfusion rat model
Oxymatrine attenuates osteoclastogenesis via modulation of ROS-mediated SREBP2 signaling and counteracts ovariectomy-induced osteoporosis
Preparation, optimization and cellular uptake study of tanshinone I nanoemulsion modified with lactoferrin for brain drug delivery
Differential change in cortical and hippocampal monoamines, and behavioral patterns in streptozotocin-induced type 1 diabetes rats
Taking aim at Alzheimerโs disease through the mammalian target of rapamycin
Scientific Evidence for Korean Medicine and Its Integrative Medical Research 2017
Therapeutic potential of phytoconstituents in management of Alzheimerโs disease
Protection of MCC950 against Alzheimerโs disease via inhibiting neuronal pyroptosis in SAMP8 mice
Intranasal treatment of neurodegenerative diseases and stroke
Programming apoptosis and autophagy with novel approaches for diabetes mellitus
Entanglement of UPRER in Aging Driven Neurodegenerative Diseases
Epigallocatechin-3-Gallate (EGCG) improves cognitive deficits aggravated by an obesogenic diet through modulation of unfolded protein response in APPsweย โฆ
Neuroprotective Effects of Heat-Killed Lactobacillus plantarum 200655 Isolated from Kimchi Against Oxidative Stress
Pharmacological Basis for Use of Armillaria mellea Polysaccharides in Alzheimerโs Disease: Antiapoptosis and Antioxidation
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy
Longโterm behavioral, histological, biochemical and hematological evaluations of amyloid betaโinduced Alzheimerโs disease in rat
Expression of early growth response 1 affects miR-106a/signal transducer and activator of transcription 3 regulating cognitive impairment in ovariectomized mice
The Treatment of Brain Inflammation in Alzheimerโs Disease. Can Traditional Medicines Help
Impact of gut microbiome manipulation in 5xFAD mice on Alzheimerโs disease-like pathology
Chinese medicine: a hope for neurodegenerative diseases?
Effects of global ischemia duration on neuronal, astroglial, oligodendroglial, and microglial reactions in the vulnerable hippocampal CA1 subregion in rats
Phosphodiesterase-5 inhibitors: Shedding new light on the darkness of depression?
Autophagy and Proteostasis
Gut microbiota in Alzheimerโs disease, depression, and type 2 diabetes mellitus: The role of oxidative stress
Molecular diagnosis and drug development in both Alzheimerโs and Parkinsonโs diseases
Short-term maintenance on a high-sucrose diet alleviates aging-induced sleep fragmentation in drosophila
Ginsenoside Re and Rd enhance the expression of cholinergic markers and neuronal differentiation in Neuro-2a cells
Effect of statins on amyloidosis in the rodent models of Alzheimerโs disease: Evidence from the preclinical meta-analysis
Long-lasting sex-specific effects based on emotion-and cognition-related behavioral assessment of adult rats after post-traumatic stress disorder from differentย โฆ
Alzheimerโs disease and type 2 diabetes mellitus: Pathophysiologic and pharmacotherapeutics links
Neuroprotective and preventative effects of molecular hydrogen
The cardioprotective potential of Tadalafil in myocardial ischemia/reperfusion
The effect of induced diabetes mellitus on the cerebellar cortex of adult male rat and the possible protective role of oxymatrine: a histological, immunohistochemicalย โฆ
Anti-neuroinflammatory effect of short-chain fatty acid acetate against Alzheimerโs disease via upregulating GPR41 and inhibiting ERK/JNK/NF-ฮบB
Chronic Polyphenon-60 or Catechin treatments increase brain monoamines syntheses and hippocampal SIRT1 levels improving cognition in aged rats
Multimodal markers of inflammation in the subcortical ischemic vascular disease type of vascular cognitive impairment
New insights into the roles of microglial regulation in brain plasticity-dependent stroke recovery
Therapeutic potential of widely used unani drug Asl-Us-Soos (Glycyrrhiza glabra Linn.): a systematic review
Early maternal separation promotes apoptosis in dentate gyrus and alters neurological behaviors in adolescent rats
Serum Ghrelin in Mild Cognitive Impairment and Alzheimerโs Disease A Systematic Review and Meta-analysis
Antioxidative, anti-inflammatory and anti-apoptotic effects of ellagic acid in liver and brain of rats treated by D-galactose
Current concepts on selected plant secondary metabolites with promising inhibitory effects against enzymes linked to Alzheimerโs disease
A focus on valproate and cognitive deficits in Bipolar Disorders: A mini-review: Special Section on โTranslational and Neuroscience Studies in Affective Disordersโย โฆ
Protective effects of beta glucan in brain tissues of post-menopausal rats: a histochemical and ultra-structural study
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-ฮบB pathway
Influence of okadaic acid on hyperphosphorylation of tau and nicotinic acetylcholine receptors in primary neurons
The Neuroprotective Effect of Hericium erinaceus Extracts in Mouse Hippocampus after Pilocarpine-Induced Status Epilepticus
MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated proteinย โฆ
Neuroprotective effects of Danggui-Jakyak-San on rat stroke model through antioxidant/antiapoptotic pathway
HSP90 inhibitor 17AAG attenuates sevoflurane-induced neurotoxicity in rats and human neuroglioma cells via induction of HSP70
Can co-activation of Nrf2 and neurotrophic signaling pathway slow Alzheimerโs disease?
Proteolytic cleavage of proBDNF to mBDNF in neuropsychiatric and neurodegenerative diseases
Review on the third international neuroinflammation congress and student festival of neuroscience in mashhad university of medical sciences
Tanshinone I induces cyclin D1 proteasomal degradation in an ERK1/2 dependent way in human colorectal cancer cells
Inhibition of the self-assembly of Aฮฒ and of tau by polyphenols: Mechanistic studies
Environmental enrichment induces synaptic structural modification after transient focal cerebral ischemia in rats
Erythropoietin and mTOR: a โone-two punchโ for aging-related disorders accompanied by enhanced life expectancy
Natural modulators of amyloid-beta precursor protein processing
Memory-enhancing effect of Mori Fructus via induction of nerve growth factor
Modulation of Hallmarks of Brain Aging by Environmental Enrichment
Elucidation of Arctigenin Pharmacokinetics After Intravenous and Oral Administrations in Rats: Integration of In Vitro and In Vivo Findings via Semi-mechanisticย โฆ
Gut microbiota: critical controller and intervention target in brain aging and cognitive impairment
Ginsenoside compound K promotes ฮฒโamyloid peptide clearance in primary astrocytes via autophagy enhancement
Associations of green tea consumption and cerebrospinal fluid biomarkers of Alzheimerโs disease pathology in cognitively intact older adults: the cable study
p53 and clock genes play an important role in memory and learning ability depression due to long-term ultraviolet A eye irradiation
Therapeutic potential of multifunctional derivatives of cholinesterase inhibitors
Dihydromyricetin attenuates metabolic syndrome and improves insulin sensitivity by upregulating insulin receptor substrate-1 (Y612) tyrosine phosphorylation in db/dbย โฆ
Autophagy and neurodegeneration
L655, 240, acting as a competitive BACE1 inhibitor, efficiently decreases ฮฒ-amyloid peptide production in HEK293-APPswe cells
Effect of Both Phytoestrogen and Xenoestrogen on Some Sexual Hormones in Male Albino Rats and Illustration of The Effect of Arctium Lappa L (A. Lappa) on Theirย โฆ
Characterization of lactic acid bacteria derived exopolysaccharides for use as a defined neuroprotective agent against amyloid beta1โ42-induced apoptosisย โฆ
Effect of the plant flavonoid, rhoifolin, on memory and cognition in a rat model of Alzheimerโs disease
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments
Dissecting Endoplasmic Reticulum Unfolded Protein Response (UPRER) in Managing Clandestine Modus Operandi of Alzheimerโs Disease
Selenomethionine attenuates the Amyloid-ฮฒ level by both inhibiting Amyloid-ฮฒ production and modulating autophagy in neuron-2a/AฮฒPPswe cells
Plasticity as a therapeutic target for improving cognition and behavior in Down syndrome
Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone
Black carrots fermented with Lactobacillus plantarum or Aspergillus oryzae prevent cognitive dysfunction by improving hippocampal insulin signalling in amyloid-ฮฒย โฆ
Adiponectin: A potential target for obesity-associated Alzheimerโs disease
Zearalenone as an endocrine disruptor in humans
Emerging therapeutic strategies in Alzheimerโs disease
Hydrogen sulfide protects against cognitive impairment induced by hepatic ischemia and reperfusion via attenuating neuroinflammation
Neuroprotection and cognitive enhancement by treatment with ฮณ-oryzanol in sporadic Alzheimerโs disease
ERฮฑ gene promoter methylation in cognitive function and quality of life of patients with Alzheimer disease
Identification of potential gene signatures related to sleep deprivation
Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice
Guarana (Paullinia cupana Mart.) protects against amyloid-ฮฒ toxicity in Caenorhabditis elegans through heat shock protein response activation
Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aฮฒ1โ42 to the Rat Brain
The Effects of Prebiotics and Probiotics on Mental Disorders
Analysis of the memory trace nature in passive avoidance response
Syntaxin 1B mediates berberineโs roles in epilepsy-like behavior in a pentylenetetrazole-induced seizure zebrafish model
Analysis of immune-related key genes in Alzheimerโs disease
Study of a Novel Curcumin-derived TFEB Activator C1 and Experimental Alzheimerโs Disease
The flavone luteolin improves central nervous system disorders by different mechanisms: a review
Autophagy and Alzheimerโs disease: from molecular mechanisms to therapeutic implications
A peptide binding to the ฮฒ-site of APP improves spatial memory and attenuates Aฮฒ burden in Alzheimerโs disease transgenic mice
Interpreting Alzheimerโs disease clinical trials in light of the effects on amyloid-ฮฒ
Acylated ghrelin as a multi-targeted therapy for Alzheimerโs and Parkinsonโs disease
Growth hormone (GH) and synaptogenesis
Natural products as potential anti-Alzheimer agents
Danggui-Jakyak-San enhances hippocampal long-term potentiation through the ERK/CREB/BDNF cascade
Oligodendrocytes and Alzheimerโs disease
The effects of Chunghyul-Dan, an agent of Korean medicine, on a mouse model of traumatic brain injury
Ferulic acid attenuates microglia-mediated neuroinflammation in retinal degeneration
MK0677, a ghrelin mimetic, improves neurogenesis but fails to prevent hippocampal lesions in a mouse model of Alzheimerโs disease pathology
Alternative Anti-Infective/Anti-Inflammatory Therapeutic Options for Fighting Alzheimerโs
Substrate-Specific Activation of ฮฑ-Secretase by 7-Deoxy-Trans-Dihydronarciclasine Increases Non-Amyloidogenic Processing of ฮฒ-Amyloid Protein Precursor
Exercise training promotes SIRT1 activity in aged rats
Effects of pre-pregnancy chronic valproate administration in female rats on avoidance memory and hippocampal gene expression of offspring
Piperine-a major principle of black pepper: a review of its bioactivity and studies
Detection of Arctigenin in
Guarana (Paullinia cupana) extract protects Caenorhabditis elegans models for Alzheimer disease and Huntington disease through activation of antioxidantย โฆ
Regulation of neprilysin activity and cognitive functions in rats after prenatal hypoxia
Protective and antioxidant effects of a chalconoid from Pulicaria incisa on brain astrocytes
Piperine-mediated suppression of voltage-dependent Ca 2+ influx and glutamate release in rat hippocampal nerve terminals involves 5HT 1A receptors and G proteinย โฆ
Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithiumย โฆ
Hydrogen inhalation protects hypoxicโischemic brain damage by attenuating inflammation and apoptosis in neonatal rats
Therapeutic perspectives of drugs targeting toll-like receptors based on immune physiopathology theory of Alzheimerโs disease
Phytomedicines for cns disorders: safety issues for use with antiePilePtic drugs
Psychotomimetic agent BZ (3-quinuclidinyl benzilate)
Applications in medicine: mental health
Current and future treatments for Alzheimerโs disease
Impact of Gut Microbiome Lactobacillus spp. in Brain Function and its Medicament towards Alzheimerโs Disease Pathogenesis.
Voltage-gated potassium channels are involved in oxymatrine-regulated islet function in rat islet ฮฒ cells and INS-1 cells
Increased postsynaptic density protein-95 expression in the frontal cortex of aged cognitively impaired rats
Effect of daily tadalafil on reported outcomes in patients with erectile dysfunction and depressive symptoms: STROBE, a caseโcontrol study
Signaling pathway cross talk in Alzheimerโs
Peptide fragment of thymosin ฮฒ4 increases hippocampal neurogenesis and facilitates spatial memory
Characteristics, biological properties and analytical methods of piperine: A review
Change in plasma lactate concentration during arctigenin administration in a phase I clinical trial in patients with gemcitabine-refractory pancreatic cancer
The potential roles of ghrelin in metabolic syndrome and secondary symptoms of Alzheimerโs disease
Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice
Metabolic regulation and genetic engineering of pharmaceutical component tanshinone biosynthesis in Salvia miltiorrhiza
TRAP1 in oxidative stress and neurodegeneration
Early life stress: consequences for the development of the brain
Exenatide attenuates obesity-induced mitochondrial dysfunction by activating SIRT1 in renal tubular cells
Bulbocodin D ameliorate cognitive impairment in APP/PS1 transgenic mice by modulating amyloid-beta burden, oxidative status and neuroinflammation
The poly (I: C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery
Inhibition of advanced glycation endproduct formation by lotus seedpod oligomeric procyanidins through RAGEโMAPK signaling and NF-ฮบB activation in high-fat-dietย โฆ
plant sources as potential therapeutics for Alzheimerโs disease
Role of astrocytes in an in vitro model of ischemic stroke
Plants traditionally used in age-related brain disorders (dementia): an ethanopharmacological survey
PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-ฮบB/Nrf-2 Axis
Protective properties of tanshinone I against oxidative DNA damage and cytotoxicity
Effect of Betulinic Acid Vs Simvastatin on Hypelipidemic Mice Model
Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways
Siberian Plants and Natural Mineral Salts for Dietary Supplements.
Acetylcholinesterase inhibitors for the treatment of Alzheimerโs diseaseโa patent review (2016โpresent)
Research Article Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar A to the Rat Brain
Potential of natural products in the treatment of myocardial infarction: Focus on molecular mechanisms
The effects of tadalafil and pentoxifylline on apoptosis and nitric oxide synthase in liver ischemia/reperfusion injury
Activation tagging in Salvia miltiorrhiza can cause increased leaf size and accumulation of tanshinone I and IIA in its roots
WISP1: Clinical insights for a proliferative and restorative member of the CCN family
Zearalenone alters the excitability of rat neuronal networks after acute in vitro exposure
The Role of Arctium lappa L. Extract against Zinc Oxide Nanoparticles Induced Hepato-Cardiotoxicity and Hyperlipidemia in Male Rats Nema A Mohamed1ย โฆ
Antioxidant effects of piperine in in-vivo chick embryo cataract model induced by steroids
Synergistic efficacy and diminished adverse effect profile of composite treatment of several ADHD medications
The change of human Na+/dicarboxylate co-transporter 1 expression in the kidney and its relationship with pathogenesis of nephrolithiasis
Screening and elucidation of selected natural compounds for anti-Alzheimerโs potential targeting BACE-1 enzyme: A case computational study
Pentoxifylline Enhances Antioxidative Capability and Promotes Mitochondrial Biogenesis in D-Galactose-Induced Aging Mice by Increasing Nrf2 and PGC-1ฮฑย โฆ
Health and technological aspects of methylxanthines and polyphenols from guarana: A review
Exogenous microRNA 322-5p Reduced Neuronal Inflammation via the TRAF6/IRF5/NF-kB Axis and Restored GAD1/GABA Expression in a Pilocarpine-inducedย โฆ
Ghrelin mediated hippocampal neurogenesisโimplications for health and
Is a combination of progesterone and chloroquine more effective than either alone in the treatment of cerebral ischemic injury?
28-Day Oral Chronic Toxicity Study of Arctigenin in Rats
Milk and Parkinson disease: Could galactose be the missing link
Research Article Protective and Antioxidant Effects of a Chalconoid from Pulicaria incisa on Brain Astrocytes
Lipotoxicity-associated inflammation is prevented by guarana (Paullinia cupana) in a model of hyperlipidemia
Guarana and Its Possible Effects on Health
Enhanced Biosynthesis of Dihydromyricetin in Saccharomyces cerevisiae by Coexpression of Multiple Hydroxylases
Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the ฮฑ7nAch receptor in SH-SY5Y cells
Heat shock protein 70 suppresses neuroinflammation induced by ฮฑ-synuclein in astrocytes
Arctigenin suppressed epithelial-mesenchymal transition through Wnt3a/ฮฒ-catenin pathway in PQ-induced pulmonary fibrosis
Cationic arginine-rich peptides (CARPs): a novel class of neuroprotective agents with a multimodal mechanism of action
Flavonoids for therapeutic applications
Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures
Dihydromyricetin acts as a potential redox balance mediator in cancer chemoprevention
The Aฮฒ16-22 hexamerโs aggregation under a co-effect of EGCG compound and low-pH concentration
Prospects of statins in Parkinson disease
Extrapyramidal side effects in a patient treated with risperidone plus donepezil
Research on the mechanism of high glucose affecting the apoptosis of schwann cells by Nox4 NADPH oxidase
The insulin/Akt signaling pathway is targeted by intracellular ฮฒ-amyloid
Mechanism of oxidative stress in skeletal muscle of rats induced by acute exhaustive exercise
Natural compounds preventing neurodegenerative diseases through autophagic activation
Antioxidant and anticancer activities of Lactobacillus hilgardii strain AG12a
Inhibitory effect of isoliquiritigenin isolated from Glycyrrhizae Radix on amyloid-ฮฒ production in Swedish mutant amyloid precursor protein-transfected Neuro2a cells
Resveratrol promotes neurotrophic factor release from astroglia
Dietary intake of heat-killed Lactococcus lactis H61 delays age-related hearing loss in C57BL/6J mice
Neuroprotective effect of 6-paradol enriched ginger extract by fermentation using Schizosaccharomyces pombe
Dimeric Tacrine (10)-hupyridone as a Multitarget-Directed ligand to treat Alzheimerโs disease
Agmatine alleviates epileptic seizures and hippocampal neuronal damage by inhibiting gasdermin D-mediated pyroptosis
Guarana (Paullinia cupana) consumption improves hepatic and renal parameters in alloxan-induced diabetic rats.
Chunghyuldan attenuates brain microglial inflammatory response
Role of piperine in CNS diseases: pharmacodynamics, pharmacokinetics and drug interactions
Preliminary screening of a classical ayurvedic formulation for anticonvulsant activity
Natural BACE1 Inhibitors: Promising Drugs for the Management of Alzheimerโs Disease
Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice
Development and biological characterization of novel ligands for protein-protein interaction-based effects of prolyl oligopeptidase
Protective effect of coriolus versicolor cultivated in citrus extract against nitric oxide-induced apoptosis in human neuroblastoma SK-N-MC cells
Cenobamate: Neuroprotective potential of a new antiepileptic drug
Biochemical regulation of sleep and sleep biomarkers
Early life stress and hippocampal neurogenesis in the neonate: sexual dimorphism, long term consequences and possible mediators
Piperine improves experimental autoimmune encephalomyelitis (EAE) in lewis rats through its neuroprotective, anti-inflammatory, and antioxidant effects
ฮฒ-HB inhibits the apoptosis of high glucose-treated astrocytes via activation of CREB/BDNF axis
Effects of pharmacological modulators of ฮฑ-synuclein and tau aggregation and internalization
Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats
The efficacy of low-dose tadalafil in patients undergoing hemodialysis with end-stage renal disease
Extraction, structure, pharmacological activities and drug carrier applications of Angelica sinensis polysaccharide
The effect of Lactobacillus plantarum on expression of biofilm genes of Streptococcus mutans isolated from dental caries
Clinical Uses of Piperine: A Review
Monoamine Oxidase Inhibition by Major Tanshinones from Salvia miltiorrhiza and Selective Muscarinic Acetylcholine M4 Receptor Antagonism by Tanshinone I
Metabolic Responses and Profiling of Bioorganic Phosphates and Phosphate Metabolites in Traumatic Brain Injury
7-Deoxy-trans-dihydronarciclasine Isolated from Lycoris chejuensis Inhibits Neuroinflammation in Experimental Models
ICIMH 2020 Abstracts
Investigating the probiotic characteristics of four microbial strains with potential application in feed industry
Directed Differentiation of Mouse ESC-Derived Cardiac Progenitors to Cells of Defined Fate
ฮฒโSecretase (BACE1) Inhibitors from Natural Products
Age-and nicotine-associated gene expression changes in the hippocampus of APP/PS1 Mice
Disrupted structural connectivity in ArcAฮฒ mouse model of Aฮฒ amyloidosis
Can mesenchymal stem cells act multipotential in traumatic brain injury?
Extracellular signal-regulated kinase activation in spinal astrocytes and microglia contributes to cancer-induced bone pain in rats
Effects of exercise on long-term potentiation in neuropsychiatric disorders
In vitro study of antioxidant and antibacterial activities of Lactobacillus probiotic spp.
Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
Consequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity
Qingxin Kaiqiao Fang Inhibits Aฮฒ25-35-Induced Apoptosis in Primary Cultured Rat Hippocampal Neuronal Cells via the p38 MAPK Pathway: An Experimentalย โฆ
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects
Effects of 17-AAG on neurons apoptosis induced by oxygen-glucose deprivation and recovery
Arctigenin suppresses fibroblast activity and extracellular matrix deposition in hypertrophic scarring by reducing inflammation and oxidative stress
Effect of Paullinia cupana Mart. Commercial Extract During the Aging of Middle Age Wistar Rats: Differential Effects on the Hippocampus and Striatum
Antioxidant and hyperlipidemia effect of ganoderma lucidum fungus alcoholic extract in male albino rats using tritonwr 1339
Ghrelin System Deficiency and Hippocampal Lesions in Alzheimerโs Disease
Antidepressant-like activity of the aqueous extract of Allium macrostemon in mice
Antioxidant effects of piperine on steroid-induced hepatotoxicity
Comparison of Preoperative Sedation Effect of Dexmedetomidine Nasal Spray at Different Doses in Children with Cleft Palate
A pectin from fruits of Lycium barbarum L. decreases ฮฒ-amyloid peptide production through modulating APP processing
Ferroptosis as a mechanism of neurodegeneration in
El consumo de guaranรก (Paullinia cupana) mejora los parรกmetros hepรกticos y renales en ratas diabรฉticas inducidas por aloxano
Guarana (Paullinia cupana) consumption improves hepatic and renal parameters in alloxan-induced diabetic rats
Molecular insights into the multifunctional role of natural compounds: autophagy modulation and cancer prevention
Qingxin Kaiqiao Fang Inhibits Aฮฒ25-35-Induced Apoptosis in Primary Cultured Rat Hippocampal Neuronal Cells via the p38 MAPK Pathway: An Experimentalย โฆ
The synergistic effect of raloxifene, fluoxetine, and bromocriptine protects against pilocarpine-induced status epilepticus and temporal lobe epilepsy
Correlation between Connexin 43 on Spiral Modiolar Artery and Presbycusis
Experimental inhibition of fibrillogenesis and neurotoxicity by amyloid-beta (Aฮฒ) and other disease-related peptides/proteins by plant extracts and herbal compounds
Research Progress on the Relationship between Intestinal Flora and Alzheimerโs Disease
The microbiome of the built environment and mental health
The Ethanolic Extract of Caesalpinia sappan Heartwood Inhibits Cerebral Ischemia/Reperfusion Injury in a Rat Model Through a Multi-Targetedย โฆ
In vitro evaluation of the protective effects of plant extracts against amyloid-beta peptide-induced toxicity in human neuroblastoma SH-SY5Y cells
Assay Suitability for Natural Product Screening: Searching for Leads to Fight Alzheimerสผs Disease
Antimicrobial and Antioxidant Activities of Fermented Meat Patty with Lactobacillus Strains
FATTY ACID ESTERS FROM THE ROOTS OF GLYCYRRHIZA GLABRA L.
Possible involvement of endoplasmic reticulum stress in the pathogenesis of Alzheimerโs disease
Antimicrobial activity of Lactobacillus plantarum against pathogenic and food spoilage microorganisms: a review.
Anti-hyperlipidemic and antioxidant effects of alkali-extractable mycelia polysaccharides by Pleurotus eryngii var. tuolensis
Berberine attenuates myocardial ischemia/reperfusion injury by reducing oxidative stress and inflammation response: role of silent information regulator 1
Inhibiting heat shock protein 90 protects nucleus pulposus-derived stem/progenitor cells from compression-induced necroptosis and apoptosis
The Effects of Chronic Early-life Social Isolation on Hippocampal Cell Number and Hippocampal-Dependent Learning and Memory in Male and Female Rats
INVESTIGATION OF IN VITRO AND IN VIVO ANTIOXIDANT ACTIVITIES OF FLAVONOID EXTRACT FROM ABELMOSCHUS MANIHOT (L.) MEDIC FLOWER.
Pressurized liquid-and supercritical fluid extraction of crude and waste seeds of guarana (Paullinia cupana): Obtaining of bioactive compounds and mathematicalย โฆ
Trehalose inhibits Aฮฒ generation and plaque formation in Alzheimerโs disease
Tanshinone I enhances neurogenesis in the mouse hippocampal dentate gyrus via increasing Wnt-3, phosphorylated glycogen synthase kinase-3ฮฒ and ฮฒ-cateninย โฆ
Arctigenin inhibits the activation of the mTOR pathway, resulting in autophagic cell death and decreased ER expression in ER-positive human breast cancerย โฆ
Controlling Food Poisoning Bacteria in Fermented Chicken Sausage Using Lactobacillus plantarum
Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects
The role of trophic factors and other drugs in the treatment of Huntingtonโs disease in R6/2 mouse model
Regulation of mRNA translation in neuronsโa matter of life and death
Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?
Xanthine-Catechin Mixture Enhances Lithium-Induced Anti-Inflammatory Response in Activated Macrophages In Vitro
Recombinant human erythropoietin protects against hippocampal damage in developing rats with seizures by modulating autophagy via the S6 protein in a timeย โฆ
Neurotrophic peptides, ADNF-9 and NAP, prevent alcohol-induced apoptosis at midgestation in fetal brains of C57BL/6 mouse
Physiological Effects of Caffeine and Its Congeners Present in Tea and Coffee Beverages
Gastric floating sustained-release tablet for dihydromyricetin: development, characterization, and pharmacokinetics study
Bcl-2 family members and apoptosis, taken to heart
Effects of tadalafil on ischemia/reperfusion injury in rat brain
Developmental manipulation of the hippocampal dentate gyrus to investigate effects of early life stress on adult dentate function
Arctigenin antagonizes mineralocorticoid receptor to inhibit the transcription of Na/K-ATPase
Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Tripleย โฆ
Next-generation sequencing to elucidate adaptive stress response and plantaricin genes among Lactobacillus plantarum strains
Comparative analysis of zearalenone effects on thyroid receptor alpha (TRฮฑ) and beta (TRฮฒ) expression in rat primary cerebellar cell cultures
Effects of Paullinia cupana extract on lamotrigine pharmacokinetics in rats: A herb-drug interaction on the gastrointestinal tract with potential clinical impact
Advances in Alzheimerโs Disease: From Bench to Bedside
Screening of ฮฒ-secretase and acetylcholinesterase inhibitors from plant resources
Biological Activity of Bicyclic and Tricyclic Diterpenoids from Salvia Species of Immediate Pharmacological and Pharmaceutical Interest
Lignans and aromatic glycosides from Piper wallichii and their antithrombotic activities
The Effect of Eight Weeks of Intermittent Training with Quercetin Encapsulated Nanoparticles on JNK and ERK Apoptosis Regulators in the Rat Model of Myocardialย โฆ
Extraction, purification, and antioxidant activity of exopolysaccharides produced by Lactobacillus kimchi SR8 from sour meat in vitro and in vivo
Network meta-analysis: Aspirin plus traditional Chinese medicine for stroke prevention in patients with atrial fibrillation
Anti-inflammation associated protective mechanism of berberine and its derivatives on attenuating pentylenetetrazole-induced seizures in zebrafish
Research Article Xanthine-Catechin Mixture Enhances Lithium-Induced Anti-Inflammatory Response in Activated Macrophages In Vitro
The microbiota, immunoregulation, and mental health: implications for public health
Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus
The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontalย โฆ
A novel peptide, colivelin, prevents alcohol-induced apoptosis in fetal brain of C57BL/6 mice: signaling pathway investigations
Analysis of Side Population in Solid Tumor Cell Lines
Supplementary Information for
Dihydromyricetin attenuates Escherichia coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3 inflammasome and TLR4/NF-ฮบBย โฆ
Delivery of Arctiin via Ultrasound with Microbubbles Exerted Positive Effects on Motor Function in a Transgenic Mice Model of Amyotrophic Lateral Sclerosis
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimerโs disease
Structural modification of natural product tanshinone I leading to discovery of novel nitrogen-enriched derivatives with enhanced anticancer profile and improved drugย โฆ
Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish
Molecular and Cellular Substrates for the Friedreich Ataxia. Significance of Contactin Expression and of Antioxidant Administration
Effects of Hsp70.1 Gene Knockout on the Mitochondrial Apoptotic Pathway After Focal Cerebral Ischemia
Hydroxylated chalcones as aryl hydrocarbon receptor agonists: structure-activity effects
Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury
Role of mitogen-and stress-activated kinases in ischemic injury
Phellinus linteus: a promising mycelium against cancer or immune disorders
Hsp90: Is There an Unknown Role in Pain Neurobiology
Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells
Histone acetylation and expression of mono-aminergic transmitters synthetases involved in CUS-induced depressive rats
Supplemental Table Legend
Regioselective glucuronidation of tanshinone iia after quinone reduction: identification of human UDP-glucuronosyltransferases, species differences, and interactionย โฆ
The Bioactivities and Potential Clinical Values of Angelica Sinensis Polysaccharides
Cold hands, warm feet: sleep deprivation disrupts thermoregulation and its association with vigilance
Endoplasmic reticulum stress and Nox-mediated reactive oxygen species signaling in the peripheral vasculature: potential role in hypertension
Effects of surface modification on delivery efficiency of biodegradable nanoparticles across the bloodโbrain barrier
The gastroprotective effect of pogostone from Pogostemonis Herba against indomethacin-induced gastric ulcer in rats
Activation of the Akt/GSK3ฮฒ signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats
FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway
Glucosylpolyphenols as inhibitors of Aฮฒ-induced Fyn kinase activation and tau phosphorylation: synthesis, membrane permeability, and exploratory target assessmentย โฆ
LICORICE TOWARDS SAFE USE
Preventive effect of Bacillus mojavensis levan against carbon tetrachloride and cisplatin toxicity: in vivo study
2-Pentadecyl-2-oxazoline (PEAOXA): an anti-inflammatory and anti-nociceptive compound and its impact in the marine environment in a model of Zebrafishย โฆ
Targeted hsp70.1 Disruption Increases Infarction Volume After Focal Cerebral Ischemia in Mice
Proteome profiling of different rat brain regions reveals the modulatory effect of prolonged maternal separation on proteins involved in cell death-relatedย โฆ
Autophagy and Signaling
Cyclic cis-locked phospho-dipeptides reduce entry of AฮฒPP into amyloidogenic processing pathway
Regulation of expression and function of neurokine receptors
Iron regulation and heat shock proteins in ischemic stroke
Patent application title: HUMANIN, ANALOGS AND CANCER TREATMENT METHODS AND USES THEREOF Inventors: Ronald S. Swerdloff (Long Beachย โฆ
Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation
DMTHB ameliorates memory impairment in Alzheimerโs disease mice through regulation of neuroinflammation
Tanshinone IIA regulates glycogen synthase kinase-3ฮฒ-related signaling pathway and ameliorates memory impairment in APP/PS1 transgenic mice
Physical exercise ameliorates memory impairment in offspring of old mice
SAG treatment ameliorates memory impairment related to sleep loss by upregulating synaptic plasticity in adolescent mice
Salidroside ameliorates memory impairment following long-term ethanol intake in rats by modulating the altered intestinal microbiota content andย โฆ
Umbelliferone Ameliorates Memory Impairment and Enhances Hippocampal Synaptic Plasticity in Scopolamine-Induced Rat Model
Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3ร Tg-AD mice
Therapeutic inhibition of HMGB1 suppress seizures and ameliorates memory impairment in adult zebrafish
Adansonia digitata ameliorates lead-induced memory impairments in rats by reducing glutamate concentration and oxidative stress
Viola tricolor Hydroalcoholic Extract Improves Behavioral Deficiencies in Rats Exposed to Chronic Immobilization Stress
Protective effect of miR-34c antagomir against STZ-induced memory impairment by targeting mTOR and PSD-95 in the hippocampus of rats
Guarana (Paullinia cupana Kunth): Applications to Alzheimerโs disease and dementias
Activation of TGR5 ameliorates streptozotocin-induced cognitive impairment by modulating apoptosis, neurogenesis, and neuronal firing
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice
Humanin derivative, HNG, enhances neurotransmitter release
Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies
Luteolin ameliorates depression-like behaviors by suppressing ER stress in a mouse model of Alzheimerโs disease
Nacre extract from pearl oyster attenuates amyloid beta-induced memory impairment
Erythropoietin improve spatial memory impairment following methamphetamine neurotoxicity by inhibition of apoptosis, oxidative stress and neuroinflammation in CA1ย โฆ
Dexmedetomidine prevents spatial learning and memory impairment induced by chronic REM sleep deprivation in rats
A Purine Derivative Containing an Organoselenium Group Protects Against Memory Impairment, Sensitivity to Nociception, Oxidative Damage, andย โฆ
Rosinidin protects streptozotocin-induced memory impairment-activated neurotoxicity by suppressing oxidative stress and inflammatory mediators in rats
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimerโs disease-like behavioral rat model
The Protective Effects of the Combination of Vitamin E and Swimming Exercise on Memory Impairment Induced by Exposure to Waterpipe Smoke
Treatment combining focused ultrasound with gastrodin alleviates memory deficit and neuropathology in an Alzheimerโs disease-like experimental mouseย โฆ
Recent advances in research on polyphenols: effects on microbiota, metabolism, and health
Naringin prevents the reduction of the number of neurons and the volume of CA1 in a scopolamine-induced animal model of Alzheimerโs disease (AD): a stereologicalย โฆ
Leptin ameliorates Aฮฒ1-42-induced Alzheimerโs disease by suppressing inflammation via activating p-Akt signaling pathway
Peptide WCPFSRSF alleviates sleep deprivation-induced memory impairment by inhibiting neuroinflammation and modulating IL-6/JAK/STAT signaling pathway
Probiotics ameliorates LPS induced neuroinflammation injury on Aฮฒ 1โ42, APP, ฮณ-ฮฒ secretase and BDNF levels in maternal gut microbiota and fetalย โฆ
A Reactive Oxygen SpeciesโResponsive Targeted Nanoscavenger to Promote Mitophagy for the Treatment of Alzheimerโs Disease
Qinzhi Zhudan formula improves memory and alleviates neuroinflammation in vascular dementia rats partly by inhibiting the TNFR1-mediated TNF pathway
Myricetin prevents sleep deprivation-induced cognitive impairment and neuroinflammation in rat brain via regulation of brain-derived neurotropic factor
Dexmedetomidine attenuates sleep deprivation-induced inhibition of hippocampal neurogenesis via VEGF-VEGFR2 signaling and inhibits neuroinflammation
Dysfunction of the Brain-derived Neurotrophic Factor-Tyrosine Kinase B Signaling Pathway Contributes to Learning and Memory Impairments Induced byย โฆ
Treadmill exercise training alleviates diabetes-induced depressive-like behavior and cognitive impairment by improving hippocampal CA1 neurons injury in db/dbย โฆ
Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimerโs disease therapy
Esculetin ameliorates cognitive impairments in D-galactose-induced Alzheimerโs disease rats by inhibiting inflammation and oxidative stress
Tangeretin prevents cognitive deficit in delirium through activating RORฮฑ/ฮณ-E4BP4 axis in mice
Cyclic Glycine-Proline Improves Memory and Reduces Amyloid Plaque Load in APP/PS1 Transgenic Mouse Model of Alzheimerโs Disease
Sagacious confuciusโ pillow elixir ameliorates Dgalactose induced cognitive injury in mice via estrogenic effects and synaptic plasticity
Medicinal herbs and their derived ingredients protect against cognitive decline in in vivo models of Alzheimerโs disease
Treadmill exercise ameliorates ethanol with lipopolysaccharide and carbon tetrachloride-mediated liver injury in mice
Histone deacetylases 1 and 2 in memory function
Stem cell therapy for Alzheimerโs disease: An overview of experimental models and reality
Microbiota alteration and modulation in Alzheimerโs disease by gerobiotics: The gut-health axis for a good mind
Improvement of Ganoderma lucidum water extract on the learning and memory impairment and its mechanism in d-galactose-induced aging mice
Asiatic acid ameliorates life and health span in fruit fly.
6-Shogaol, an Active Ingredient of Ginger, Improves Intestinal and Brain Abnormalities in Proteus Mirabilis-Induced Parkinsonโs Disease Mouse Model
Engineered macrophage-biomimetic versatile nanoantidotes for inflammation-targeted therapy against Alzheimerโs disease by neurotoxin neutralization andย โฆ
Potent and Selective Inhibition of CYP1A2 Enzyme by Obtusifolin and Its Chemopreventive Effects
Vildagliptin restores cognitive function and mitigates hippocampal neuronal apoptosis in cisplatin-induced chemo-brain: Imperative roles of AMPK/Akt/CREBย โฆ
PEA-OXA ameliorates allodynia, neuropsychiatric and adipose tissue remodeling induced by social isolation
Inhibition of anandamide breakdown reduces pain and restores LTP and monoamine levels in the rat hippocampus via the CB1 receptor followingย โฆ
Frankincense diterpenes as a bio-source for drug discovery
Intestinal epithelial cell exosome launches IL-1ฮฒ-mediated neuron injury in sepsis-associated encephalopathy
PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid ฮฒ-induced oxidative damage and bone loss
Farnesol exerts protective effects against chronic sleep deprivationโinduced cognitive impairment via activation SIRT1/Nrf2 pathway in the hippocampi of adult mice
The preventive effects of probiotic Akkermansia muciniphila on D-galactose/AlCl3 mediated Alzheimerโs disease-like rats
Dengzhan Xixin injection derived from a traditional Chinese herb Erigeron breviscapus ameliorates cerebral ischemia/reperfusion injury in rats via modulation ofย โฆ
GADD34 suppresses eIF2ฮฑ phosphorylation and improves cognitive function in Alzheimerโs disease-model mice
Varenicline improves cognitive impairment in a mouse model of mPFC ischemia: The possible roles of inflammation, apoptosis, and synaptic factors
Repeated social defeat stress exacerbates lipopolysaccharide-induced behavioural deficits in mice: ameliorative role of Chrysophyllum albidum fruit extract throughย โฆ
Parental exposure of Tadalafil has beneficial effect on reflexive motor behaviors in mice offspring
Oxymatrine ameliorates myocardial injury by inhibiting oxidative stress and apoptosis via the Nrf2/HO-1 and JAK/STAT pathways in type 2 diabetic rats
Gardenia jasminoides J. Ellis extract GJ-4 attenuates hyperlipidemic vascular dementia in rats via regulating PPAR-ฮณ-mediated microglial polarization
Kisspeptin-13 prevented the electrophysiological alterations induced by amyloid-beta pathology in rat: Possible involvement of stromal interaction molecules andย โฆ
Drug discovery in Alzheimerโs disease by regulating autophagy
The role of insulin signaling in hippocampal-related diseases: a focus on Alzheimerโs disease
Asiatic acid attenuates aluminium chloride-induced behavioral changes, neuronal loss and astrocyte activation in rats
Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditionalย โฆ
The action of phosphodiesterase-5 inhibitors on ฮฒ-amyloid pathology and cognition in experimental Alzheimerโs disease: A systematic review
Clinical efficacy of Danshen preparation in the treatment of vascular cognitive impairment: A systematic review and meta-analysis
Fructus gardeniae ameliorates anxiety-like behaviors induced by sleep deprivation via regulating hippocampal metabolomics and gut microbiota
Anti-aging effects of phenolic compounds
Development and In Vivo Assessment of 4-Phenyltellanyl-7-chloroquinoline-loaded Polymeric Nanocapsules in Alzheimerโs Disease Models
The neuroprotective effect of ginsenoside Rb1 on the cerebral cortex changes induced by aluminium chloride in a mouse model of Alzheimerโs disease: A histologicalย โฆ
Mitochondria in Cell-Based Therapy for Stroke
Different training patterns at recovery stage improve cognitive function in ischemic stroke rats through regulation of the axonal growth inhibitor pathway
The Effect of Intra-Medial Septum Co-Injection of Ghrelin and Nicotine on Morphine Induced Memory Impairment
Proteomics analysis of the hypothalamus of high-fat diet fed mice after Lactiplantibacillus plantarum Y44 administration
Dexmedetomidine Improves Anxiety-like Behaviors in Sleep-Deprived Mice by Inhibiting the p38/MSK1/NFฮบB Pathway and Reducing Inflammation andย โฆ
Beneficial effects of natural flavonoids on neuroinflammation
Astilbin attenuates neonatal postnatal immune activation-induced long-lasting cognitive impairment in adult mice
Neuroprotective effects of novel compound FMDB on cognition, neurogenesis and apoptosis in APP/PS1 transgenic mouse model of Alzheimerโs disease
A comparative study of the effect of a gentle ketogenic diet containing medium-chain or long-chain triglycerides on chronic sleep deprivation-induced cognitiveย โฆ
The Potential Neuroprotective Effects of Extracts from Oat Seedlings against Alzheimerโs Disease
Medicine-food herbs against alzheimerโs disease: A review of their traditional functional features, substance basis, clinical practices and mechanisms of action
Angelica purpurascens (Avรฉ-Lall.) Gilli. Essential Oil Improved Brain Function via Cholinergic Modulation and Antioxidant Effects in the Scopolamine-Induced Zebrafishย โฆ
Humulusย lupulus L. Extract Protects against Senior Osteoporosis through Inhibiting Amyloid ฮฒ Deposition and Oxidative Stress in APP/PS1 Mutatedย โฆ
Amaryllidaceae, Lycopodiaceae Alkaloids and CoumarinsโA Comparative Assessment of Safety and Pharmacological Activity
Structural fingerprinting of pleiotropic flavonoids for multifaceted Alzheimerโs disease
RAGE-TXNIP axis drives inflammation in Alzheimerโs by targeting Aฮฒ to mitochondria in microglia
Gut microbiota is an impact factor based on the brain-gut axis to alzheimerโs disease: a systematic review
Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3ฮฒ andย โฆ
Astragalus mongholicus Bunge (Fabaceae): Bioactive compounds and potential therapeutic mechanisms against Alzheimerโs disease
Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet
The Role of Plant-based Products in the Prevention of Neurological Complications
2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid ฮฒ-induced Alzheimer-like mice model: Bring the ฮฑ2 adrenergicย โฆ
Piperine provides neuroprotection against kainic acid-induced neurotoxicity via maintaining NGF signalling pathway
Centella asiatica prevents D-galactose-Induced cognitive deficits, oxidative stress and neurodegeneration in the adult rat brain
Exosomal miRโ532โ5p induced by longโterm exercise rescues bloodโbrain barrier function in 5XFAD mice via downregulation of EPHA4
Exploration of chalcones and related heterocycle compounds as ligands of adenosine receptors: therapeutics development
Ferulic acid produces neuroprotection against radiation-induced neuroinflammation by affecting NLRP3 inflammasome activation
Theta and gamma oscillatory dynamics in mouse models of Alzheimerโs disease: A path to prospective therapeutic intervention
THE EFFECT OF FERULIC ACID IN PREVENTION OF LEARNING AND MEMORY DEFICIT AND HIPPOCAMPAL INJURY IN RATS UNDER CHRONICย โฆ
Angelica purpurascens (Avรฉ-Lall.) Gilli. Essential Oil Improved Brain Function via Cholinergic Modulation and Antioxidant Effects in the Scopolamine-Inducedย โฆ
ABA Supplementation Rescues IRS2 and BDNF mRNA Expression in a Triple-Transgenic Mice Model of Alzheimerโs Disease
An Overview on Chemical Constituents, Medicinal Applications, Pharmacological Activity, Toxicology, Metabolism and Pharmacokinetics of Strobilus lupuli
Mengmeng You1, Yongming Pan 1, Yichen Liu 1, Yifan Chen 1, Yuqi Wu 1, Juanjuan Si 1, Kai Wang2 and Fuliang Hu1
Glucose metabolism, neural cell senescence and Alzheimerโs disease
Herbal biomolecules acting on central nervous system
The therapeutic potential of arctigenin against multiple human diseases: A mechanistic review
Update on new trend and progress of the mechanism of polysaccharides in the intervention of Alzheimerโs disease, based on the new understanding of relevantย โฆ
Therapeutic potential of plant-derived flavonoids against inflammation
Anti-aging effect of phlorizin on D-galactoseโinduced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulationย โฆ
The effect of ghrelin on apoptosis, necroptosis and autophagy programmed cell death pathways in the hippocampal neurons of amyloid-ฮฒ 1โ42-induced rat model ofย โฆ
Advances in polysaccharides of natural source of the anti-Alzheimerโs disease effect and mechanism
Medicineโfood herb: Angelica sinensis, a potential therapeutic hope for Alzheimerโs disease and related complications
Programmed death of microglia in Alzheimerโs disease: Autophagy, ferroptosis, and pyroptosis
Iron dyshomeostasis and ferroptosis in Alzheimerโs disease: Molecular mechanisms of cell death and novel therapeutic drugs and targets for AD
Circ_0000811 acts as a miR-15b sponge and inhibits Prkar2a-mediated JAK2/STAT1 pathway to attenuate cerebral ischemic vertigo
Relationships between inflammation and age-related neurocognitive changes
Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection
The effect of ghrelin on antioxidant status in the ratโs model of Alzheimerโs disease induced by amyloid-beta
The role of the mTOR pathway in diabetic retinopathy
An intracerebroventricular injection of Aฮ (1โ42) modifies temporal profiles of spatial memory performance and oxidative status in the temporal cortex rat
Endoplasmic reticulum stress contributes to the decline in doublecortin expression in the immature neurons of mice with long-term obesity
Recent studies of atomic-resolution structures of tau protein and structure-based inhibitors
Therapeutic efficacies of berberine against neurological disorders: an update of pharmacological effects and mechanisms
General anesthesia and sleep: like and unlike
Bisphenol A exposure links to exacerbation of memory and cognitive impairment: A systematic review of the literature
Ginsenosides can target brain-derived neurotrophic factor to improve Parkinsonโs disease
Lactobacillus gasseri NK109 and Its Supplement Alleviate Cognitive Impairment in Mice by Modulating NF-ฮบB Activation, BDNF Expression, and Gutย โฆ
Research progress of EGCG in the treatment of Alzheimerโs disease
Can dietary patterns prevent cognitive impairment and reduce Alzheimerโs disease risk: Exploring the underlying mechanisms of effects
Neuroprotective effects of flavonoids
Investigation of the in vitro antidiabetic and neuroprotective effects of selected Helichrysum species against high monosaccharide-induced toxicity
Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimerโs Disease
The role of wheat embryo globulin nutrients in improving cognitive dysfunction in AD rats
Neuroinflammatory biomarkers in diabetic encephalopathy: linking cholinergic and cognitive dysfunction
Dysfunction of the BDNF-TrkB signaling pathway contributes to learning and memory impairments induced by neuroinflammation in mice
Ghrelin regulates crosstalk between apoptosis, necroptosis and autophagy programmed cell death pathways in the hippocampal neurons of amyloid-ฮฒ 1โ42-inducedย โฆ
Xanthohumol Alleviates Epileptic Seizures in Pentylenetetrazol-Induced Convulsions in Mice by Regulating Inflammation and Oxidative Stress
Berberine: a promising treatment for neurodegenerative diseases
Dexpanthenol may protect the brain against lipopolysaccharide induced neuroinflammation via anti-oxidant action and regulating CREB/BDNF signaling
The roles of catechins in regulation of systemic inflammation
Reversal of genetic brain iron accumulation by N,Nโฒ-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice
Prior maternal separation stress alters the dendritic complexity of new hippocampal neurons and neuroinflammation in response to an inflammatory stressor inย โฆ
Arbutin as a natural soluble glycosylated phenol and usage in neuroinflammation
Vitis vinifera L. Flavones Regulate Hippocampal Neurons via Autophagy in APP/PS1 Alzheimer Model Mice
Butanol Extract of Tinospora cordifolia Alleviates Acute Sleep Deprivation-Induced Impairments in Cognitive Functions and Neuromuscular Coordination in Middleย โฆ
Updates on the Role of Probiotics against Different Health Issues: Focus on Lactobacillus
EGCG attenuates the neurotoxicity of methylglyoxal via regulating MAPK and the downstream signaling pathways and inhibiting advanced glycation end productsย โฆ
Animal Models of Cognitive Deficits for Probiotic Treatment
Mitigation of behavioral deficits and cognitive impairment by antioxidant and neuromodulatory potential of Mukia madrespatana in D-galactose treated rats
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil
Palmatine, a natural alkaloid, attenuates memory deficits and neuroinflammation in mice submitted to permanent focal cerebral ischemia
Effects of supplementation with probiotics in experimental models of alzheimerโs disease: A systematic review of animal experiments
Drug Discovery from Medicinal Plants against Alzheimerโs Disease
Research Advances in the Treatment of Alzheimerโs Disease with Polysaccharides of Danggui-Shaoyao-San
Therapeutic effect of palmitoylethanolamide in cognitive decline: A systematic review and preliminary meta-analysis of preclinical and clinical evidence
METAGENOMICS: A COMPREHENSIVE REVIEW OF ITS APPLICATIONS IN ENVIRONMENTAL SCIENCE
Protective effects of polysaccharides in neurodegenerative diseases
Lactobacillus Spp.-Enhanced Memory is Strain-Dependent and Associated, in Part, with Amyloidogenic and anti-Oxidant/Oxidative Stress Interplay in Amyloid Betaย โฆ
Early time course of oxidative stress in hippocampal synaptosomes and cognitive loss following impaired insulin signaling in rats: Development of sporadicย โฆ
Neuroprotective Effects of Black Pepper and Its Bioactive Compounds in Age-Related Neurological Disorders
The Potential Neuroprotective Effect of Cyperus esculentus L. Extract in Scopolamine-Induced Cognitive Impairment in Rats: Extensive Biological and Metabolomicsย โฆ
DOCK4 regulates ghrelin production in gastric X/A-like cells
Vertigoheel promotes rodent cognitive performance in multiple memory tests
Mechanism of Velvet Antler Peptide in Preventing Mild Cognitive Impairment Based on Non-Targeted Metabolomics
Transcriptome Profiling in the Hippocampi of Mice with Experimental Autoimmune Encephalomyelitis
Deferiprone Promoted Remyelination and Functional Recovery through Enhancement of Oligodendrogenesis in Experimental Demyelination Animal Model
Neuroprotective effect of daidzein extracted from Pueraria lobate radix in a stroke model via the Akt/mTOR/BDNF Channel
Toxicodynamics of phytonutrients
All roads lead to Romeโa review of the potential mechanisms by which exerkines exhibit neuroprotective effects in Alzheimerโs disease
Current Trends in the Animal Models for Screening of Nootropic Agents: A Systematic Review
Selected natural products in neuroprotective strategies for Alzheimerโs diseaseโa non-systematic review
Impaired Insulin Signaling Alters Mediators of Hippocampal Synaptic Dynamics/Plasticity: A Possible Mechanism of Hyperglycemia-Induced Cognitiveย โฆ
A new insight on feasibility of pre-, pro-, and synbiotics-based therapies in Alzheimerโs disease
Molecular mechanisms of Alzheimerโs disease: From therapeutic targets to promising drugs
Chemical composition and anti-aging effects of standardized herbal chicken essence on D-galactose-induced senescent mice
Notopterygium incisum Root Extract (NRE) Alleviates Epileptiform Symptoms in PTZ-Induced Acute Seizure Mice
Development of a Rapid LC-MS/MS Method for Simultaneous Quantification of Donepezil and Tadalafil in Rat Plasma: Its Application in a Pharmacokineticย โฆ
Neuroprotective efficacy of berberine following developmental exposure to chlorpyrifos in F1 generation of Wistar rats: Apoptosis-autophagy interplay
Nanomedicine-driven therapeutic interventions of autophagy and stem cells in the management of Alzheimerโs disease
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1ฮฑ/PPARฮณ Signaling
Bioinformatics Approaches to Identify Novel Therapeutic Targets of Mixed Dementia
Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach
Investฤฑgatฤฑon of the protectฤฑve effect of long-term exercฤฑse on molecular pathways and behavฤฑours ฤฑn scopolamฤฑne ฤฑnduced alzheฤฑmerโs dฤฑsease-lฤฑke condฤฑtฤฑon
Strategies for Treatment of Disease-Associated Dementia Beyond Alzheimerโs Disease: An Update
Effect of Lactobacillus sakei OK67 in Reducing Body and Visceral Fat in Lifestyle-Modified Overweight Individuals: A 12-Week, Randomized, Double-Blindย โฆ
Protein synthesis modulation as a therapeutic approach for amyotrophic lateral sclerosis and frontotemporal dementia
Dexmedetomidine alleviates anxiety-like behaviors in female mice with musculoskeletal pain through SIRT1/p53 axis
Ferroptosis inhibition by deferiprone, attenuates myelin damage and promotes neuroprotection in demyelinated optic nerve
Effects of supplementation with probiotics in experimental models of alzheimerโs disease: a systematic review of animal experiments
Neuroprotective and anti-epileptic potentials of genus Artemisia L.
Xiaoyao powder alleviates the hippocampal neuron damage in chronic unpredictable mild stress-induced depression model rats in hippocampus via connexinย โฆ
Sanwei DouKou Decoction ameliorate Alzheimer disease by increasing endogenous neural stem cells proliferation through the Wnt/ฮฒ-catenin signalling pathway
Cytokines, synaptic plasticity and network dynamics: a matter of balance
Acetylation Mechanism and HDAC Enzymes in Neurodegenerative Diseases
Investigation of the Protective Effect of Long-Term Exercise on Molecular Pathways and Cognitive Behaviors in Alzheimer Disease Model
Phytochemicals, biological activity, and industrial application of lotus seedpod (Receptaculum Nelumbinis): A review
Arctigenin: A Potential Component with Multifaceted Therapeutic Properties
Network pharmacology and molecular docking prediction, combined with experimental validation to explore the potential mechanism of Qishen Yiqi pills against HFย โฆ
The Beneficial Role of Natural Antioxidants in Alleviating Neuroinflammatory Disorders Including Neurodegeneration
N-Acetyl cysteine together with rutin combats oxidative toxicity by modulating Nrf2 pathway in inflammatory brainโLiver axis in scopolamine-administeredย โฆ
Functionalized curcumin/ginsenoside Rb1 dual-loaded liposomes: Targeting the blood-brain barrier and improving pathological features associated in APP/PS-1 mice
Benefits of dietary polyphenols in Alzheimerโs disease
Neuroprotective effect of physical activity in ischemic stroke: Focus on the neurovascular unit
The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline
Pharmacological activity of saffron and crocin on dementia: a narrative review
Hippocampal neurogenesis and Arc expression are enhanced in high-fat fed prepubertal female pigs by a diet including omega-3 fatty acids andย โฆ
Acute sleep deprivation-induced anxiety and disruption of hypothalamic cell survival and plasticity: a mechanistic study of protection by butanol extract of tinosporaย โฆ
Gerobiotics: Probiotics for Healthy Aging
Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR
Natural Compound 2, 2โฒ, 4โฒ-Trihydroxychalcone Suppresses T Helper 17 Cell Differentiation and Disease Progression by Inhibiting Retinoid-Relatedย โฆ
Metabolic hormones mediate cognition
The Potential of Edible and Medicinal Resource Polysaccharides for Prevention and Treatment of Neurodegenerative Diseases
Arctigenin improves neuropathy via ameliorating apoptosis and modulating autophagy in streptozotocinโinduced diabetic mice
Effect of Chinese herbal medicine therapy on risks of all-cause mortality, infections, parasites, and circulatory-related mortality in HIV/AIDS patients withย โฆ
Assessment of hypolipidemic and antiโinflammatory properties of walnut (Juglans regia) seed coat extract and modulates some metabolic enzymes activity in tritonย โฆ
A flavonoid on the brain: quercetin as a potential therapeutic agent in central nervous system disorders
A comprehensive review on the prevention and regulation of Alzheimerโs disease by tea and its active ingredients
Involvement of environmentally relevant toxic metal mixture in Alzheimerโs disease pathway alteration and protective role of berberine: Bioinformatics analysis andย โฆ
Probiotic supplementation demonstrates therapeutic potential in treating gut dysbiosis and improving neurocognitive function in age-related dementia
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products
Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway
Daily Consumption of High-Polyphenol Olive Oil Enhances Hippocampal Neurogenesis in Old Female Rats
TREM2 Inhibits Tau Hyperphosphorylation and Neuronal Apoptosis via the PI3K/Akt/GSK-3ฮฒ Signaling Pathway In vivo and In vitro
Gardenia jasminoides Extract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway
Neuro-Nutraceutical Polyphenols: How Far Are We?
From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders
Arctigenin: pharmacology, total synthesis, and progress in structure modification
Effects of Transient Electrical Acupuncture Stimulation Combined With Rehabilitation Training on Hemorheology, Neurological Function and BDNF in Patientsย โฆ
Demethyleneberberine, a potential therapeutic agent in neurodegenerative disorders: a proposed mechanistic insight
Arctigenin attenuates paraquat-induced human lung epithelial A549 cell injury by suppressing ROS/p38 mitogen-activated protein kinases-mediatedย โฆ
Microbiome Alterations and Alzheimerโs Disease: Modeling Strategies with Transgenic Mice
Effect of ginsenoside Rg1 on learning and memory ability of brain aging mice induced by D-galactose
A review of glucoregulatory hormones potentially applicable to the treatment of Alzheimerโs disease: mechanism and brain delivery
Bifidobacterium animalis MSMC83 Improves Oxidative Stress and Gut Microbiota in D-Galactose-Induced Rats
Subโchronic administration of lead alters markers of oxidative stress, acetylcholinesterase and Na+ K+โATPase activities in rat brain
Protective Efficacy of Spilanthes acmella Murr. Extracts and Bioactive Constituents in Neuronal Cell Death
Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy
Expression of Trace Amine-Associated Receptors in the Murine and Human Hippocampus Based on Public Transcriptomic Data
Metabolomics study suggests the mechanism of different types of tieguanyin (Oolong) tea in alleviating Alzheimerโs disease in APP/PS1 transgenic mice
Zederone improves the fecal microbial profile in dementia induced rat model: a first report
Antioxidative potential of Lactobacillus sp. in ameliorating D-galactose-induced aging
Dementia Is Induced via the AGEs/Iba1/iNOS Pathway in Aged KK-Ay/Tajcl Mice
Mushroom natural products in neurodegenerative disease drug discovery
Natural product-based bioactive agents in combination attenuate neuroinflammation in a tri-culture model
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice
Neuroprotective effects of PRG on Aฮฒ25-35-induced cytotoxicity through activation of the ERK1/2 signaling pathway
Mechanism of molecular activity of yolkinโa polypeptide complex derived from hen egg yolkโin PC12 cells and immortalized hippocampal precursor cellsย โฆ
Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimerย โฆ
Therapeutic effects of green tea polyphenol (โ)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stressย โฆ
Therapeutic Potential of Natural Compounds in Neurodegenerative Diseases: Insights from Clinical Trials
Depression-like Behavior and Alterations of Neurotransmitters and the Corresponding Receptors in the Triple Transgenic Mouse Model of Alzheimerโs Disease
Lost in translation: Neurotrophins biology and function in the neurovascular unit
Protective effect of rutin on spinal motor neuron in rats exposed to acrylamide and the underlying mechanism
The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke Recovery
Plant Extracts in Neurodegenerative Diseases
What can traditional Chinese medicine do for adult neurogenesis?
In vivo activities of the structured lipids-1, 3-dioleic acid 2-palmitic acid triglyceride (OPO) in high-fat diet mice
Intestinal Disorder in Zebrafish Larvae (Danio rerio): The Protective Action of N-Palmitoylethanolamide-oxazoline
Analysis of anesthetic effect of dexmedetomidine in femoral shaft fracture surgery
Network pharmacology analysis and experimental validation of kaempferol in the treatment of ischemic stroke by inhibiting apoptosis and regulatingย โฆ
Research and development of natural product tanshinone I: pharmacology, total synthesis, and structure modifications
Diminution in the Expression of Markers of Diabetic Retinopathy in Human Retinal Microvascular Endothelial Cells by Arctiin.
Several Key Health Benefits of Tea Polyphenols
Semi-Synthesis of Different Pyranoflavonoid Backbones and the Neurogenic Potential
Dihydromyricetin promotes GLP-1 release and glucose uptake by STC-1 cells and enhances the effects of metformin upon STC-1 cells and diabetic mouse model
Perspectives of herbs and their natural compounds, and herb formulas on treating diverse diseases through regulating complicated JAK/STAT signaling
Downregulation of miR-210 Promoted Apoptosis of Hippocampal Neurons by Negatively Regulating the TLR4/NF-ะบB1 Signaling Pathway in a Rat Model of Statusย โฆ
Exploration and Clinical Verification of the Blood Co-Expression Genes of Type 2 Diabetes Mellitus and Mild Cognitive Dysfunction in the Elderly
Potential of therapeutic small molecules in apoptosis regulation in the treatment of neurodegenerative diseases: An updated review
Ghrelin mediated hippocampal neurogenesis
Antioxidant Therapy Reduces Oxidative Stress, Restores Na, K-ATPase Function and Induces Neuroprotection in Rodent Models of Seizure and Epilepsy: Aย โฆ
Inhibition of Dyrk1A Attenuates LPS-Induced Neuroinflammation via the TLR4/NF-ฮบB P65 Signaling Pathway
Lactobacillus acidophilus KBL409 Reduces Kidney Fibrosis via Immune Modulatory Effects in Mice with Chronic Kidney Disease
Tetramethylpyrazine promotes remyelination by conversing M1 to M2 polarization of microglia via JAK2-STAT1/3 and GSK3-NFฮบB signaling pathways in ischemicย โฆ
Identification and analysis of chemical constituents of total glycosides of Cistanche deserticola YC Ma in rat hepatic metabolism by ultra performance liquidย โฆ
Mechanism of Stat1 in the neuronal Ca2+ overload after intracerebral hemorrhage via the H3K27ac/Trpm7 axis
Astrocyte Dysregulation and Calcium Ion Imbalance May Link the Development of Osteoporosis and Alzheimerโs Disease
Potential targets and mechanisms of Guarana in the treatment of Alzheimerโs disease based on network pharmacology
Phytochemical, Pharmacological, and Health Benefits of Glycyrrhiza glabra
Elucidating the promising role of traditional Chinese medicine in neuroprotection against oxidative stress encompassing Alzheimerโs disease
Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats
ApoE4-mediated Blood-Brain Barrier Damage in Alzheimerโs Disease: Progress and Prospects
Rational Design of Multifunctional Ferulic Acid Derivatives Aimed for Alzheimerโs and Parkinsonโs Diseases
Appraisal of the Neuroprotective Effect of Dexmedetomidine: A Meta-Analysis
Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy
MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-ฮบB axis in a rat epilepsy model
Dexmedetomidine alleviates airway hyperresponsiveness and allergic airway inflammation through the TLR4/NFโฮบB signaling pathway in mice
Effect of Lactobacillus brevis (MG000874) on Antioxidant Related Genes Expression of liver and kidney in d-galactose Induced Oxidative stress Mice Modelโ
Effect of Lactobacillus brevis (MG000874) on antioxidant-related gene expression of the liver and kidney in D-galactose-induced oxidative stress mice model
Neuroprotective properties of antiepileptics: what are the implications for psychiatric disorders?
Present status, challenges, and prospects of dihydromyricetin in the battle against cancer
Experimental verification for numerical simulation of thalamic stimulation-evoked calcium-sensitive fluorescence and electrophysiology with self-assembledย โฆ
Additive effect of histamine and muscimol upon induction of antinociceptive and antidepressant effects in mice
Ghrelin alleviates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells
Jasminoidin and ursodeoxycholic acid exert synergistic effect against cerebral ischemia-reperfusion injury via Dectin-1-induced NF-ฮบB activation pathway
Transโmetallated chlorophyllin by copper supported on silicaโcoated magnetic nanoparticles as an efficient and green catalyst for the synthesis of furanโ2(5H)โones
Therapeutic effects and mechanisms of Ku-Gan formula on atopic dermatitis: A pilot clinical study and modular pharmacology analysis with animal validation
Traditional Crude Drugs Against Encephalitis Infection: Ethnopharmacology, Chemistry, and Clinical and Preclinical Studies
Lactic acid bacteria profiles associated to Thai traditional fermented foods
Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3ฮฒ pathway
Tapioca starch and skim milk support probiotic efficacy of Lactiplantibacillus plantarum post-fermentation medium against pathogens and cancer cells
A monocarboxylate transporter rescues frontotemporal dementia and Alzheimerโs disease models
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