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Restore Insulin Sensitivity
Restore Insulin Sensitivity
Metformin trims fats to restore insulin sensitivity
The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice
Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C
Normalization of insulin sensitivity with lithium in diabetic rats
Improved insulin sensitivity in patients with type I diabetes mellitus after CSII
D-chiro-inositol–its functional role in insulin action and its deficit in insulin resistance
Exercise intensity, inflammatory signaling, and insulin resistance in obese rats.
insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver
FXR activation normalizes insulin sensitivity in visceral preadipocytes of a rabbit model of MetS
Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes
Phospholipid environment alters hormone-insulin sensitivity of the purified insulin receptor kinase
Palmitoleic acid reduces intramuscular lipid and restores insulin sensitivity in obese sheep
insulin resistance induced by tumor necrosis factor-α in myocytes and brown adipocytes
n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator–activated receptor-α–dependent manner
Osteocalcin reverses endoplasmic reticulum stress and improves impaired insulin sensitivity secondary to diet-induced obesity through nuclear factor-κB signaling …
Effect of hepatic denervation on peripheral insulin sensitivity in conscious dogs
Metabolic impact of puberty on the course of type 1 diabetes.
Activating the longevity gene to restore insulin sensitivity and immune reciprocity in patients with metabolic syndrome
Hyperglycemia-induced insulin resistance in diabetic dyslipidemic Yucatan swine
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats
Co‐administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats
C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes
Dehydroepiandrosterone decreases serum tumor necrosis factor-α and restores insulin sensitivity: independent effect from secondary weight reduction in genetically …
Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways
Liver-specific igf-1 gene deletion leads to muscle insulin ininsulin sensitivity
Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action
Setting the stage: possible mechanisms by which acute contraction restores insulin sensitivity in muscle
Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin …
Short‐term suppression of plasma free fatty acids fails to improve insulin sensitivity when intramyocellular lipid is elevated
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats
Linking mitochondrial bioenergetics to insulin resistance via redox biology
The association between plasma adiponectin and insulin sensitivity in humans depends on obesity
The effect of N-stearoylethanolamine on liver phospholipid composition of rats with insulin resistance caused by alimentary obesity
Dual effects of resveratrol on arterial damage induced by insulin resistance in aged mice
Skeletal muscle protein tyrosine phosphatase 1B regulates insulin sensitivity in African Americans
Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation
The effect of salicylates on insulin sensitivity
Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway
Curative diet supplementation with a melon superoxide dismutase reduces adipose tissue in obese hamsters by improving insulin sensitivity
Improved insulin sensitivity by the angiotensin receptor antagonist irbesartan in patients with systolic heart failure: A randomized double-blinded placebo-controlled …
Targeting skeletal muscle mitochondria to prevent type 2 diabetes in youth
The protein kinase IKKɛ regulates energy balance in obese mice
Bioactives of Artemisia dracunculus L. enhance insulin sensitivity by modulation of ceramide metabolism in rat skeletal muscle cells
Effect of Sutherlandia frutescens on the Lipid Metabolism in an insulin Resistant Rat Model and 3T3‐L1 Adipocytes
Metabolic rescue of obese adipose-derived stem cells by Lin28/Let7 pathway
Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals
Hypokalemia, glucose intolerance, and hyperinsulinemia during diuretic therapy.
Modelling of detailed insulin receptor kinetics affects insulin sensitivity and noise in the downstream signalling pathway
Leptin insulin sensitivity in skeletal muscle is modulated by diet and exercise
Acute inactivity impairs glycemic control but not blood flow to glucose ingestion
p53 Mediates impaired insulin signaling in 3T3‐L1 adipocytes during hyperinsulinemia
Metformin normalizes nonoxidative glucose metabolism in insulin-resistant normoglycemic first-degree relatives of patients with NIDDM
Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells
Chromium (III) propionate complex supplementation improves carbohydrate metabolism in insulin-resistance rat model
Pathways leading to muscle insulin resistance–the muscle–fat connection
Regulation of multicatalytic enzyme activity by insulin and the insulin-degrading enzyme
Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension
Pigment epithelium-derived factor contributes to insulin resistance in obesity
insulin Resistance and β-Cell Dysfunction in Aging: The Importance of Dietary Carbohydrate
Metabolic disruptions induced by reduced ambulatory activity in free-living humans
Effect of duodenal–jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease
Phosphatidylinositol 4, 5-Bisphosphate Reverses Endothelin-1–Induced insulin Resistance via an Actin-Dependent Mechanism
Imidazoline-like drugs improve insulin sensitivity through peripheral stimulation of adiponectin and AMPK pathways in a rat model of glucose intolerance
Increased 24h mean insulin-like growth factor binding protein-3 proteolytic activity in pubertal type 1 diabetic boys
S 15261, a novel agent for the treatment of insulin resistance. Studies on Psammomys obesus. Effect on pancreatic islets of insulin resistant animals.
Reduced glucose transporter GLUT4 in skeletal muscle predicts insulin resistance in non-diabetic chronic heart failure patients independently of body composition
insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
Glyceollin improves endoplasmic reticulum stress-induced insulin resistance through CaMKK-AMPK pathway in L6 myotubes
Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats
Exploring off‐target binding of thiazolidinediones and a novel mechanism for restoring insulin sensitivity (854.2)
Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes
Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
Resveratrol is not as effective as physical exercise for improving reproductive and metabolic functions in rats with dihydrotestosterone-induced polycystic …
Functional properties of Claramine: A novel PTP1B inhibitor and insulin-mimetic compound
Niacin improves adiponectin secretion, glucose tolerance and insulin sensitivity in diet-induced obese rats
insulin resistance and preeclampsia
Modulation of PPARγ activity with pharmaceutical agents: treatment of insulin resistance and atherosclerosis
Identification of influencing variables on adiponectin serum levels in diabetes mellitus type 1 and type 2
Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes
Exercise and insulin resistance
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice
Mitochondrial regulation of insulin action
What can bariatric surgery teach us about the pathophysiology of type 2 diabetes?
New series of aryloxypropanolamines with both human β3-adrenoceptor agonistic activity and free radical scavenging properties
Glycolipid metabolism disorder in the liver of obese mice is improved by TUDCA via the restoration of defective hepatic autophagy
Impaired insulin sensitivity and insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism
insulin resistance, a new target for nitric oxide‐delivery drugs
KB-R7785, a novel matrix metalloproteinase inhibitor, exerts its antidiabetic effect by inhibiting tumor necrosis factor-α production
Metabolic inflexibility in skeletal muscle: a prelude to the cardiometabolic syndrome?
Effect of acute exercise or fasting on mitochondrial function and high fat diet-induced insulin resistance
A family of Acrp30/adiponectin structural and functional paralogs
The relationship between the hyperplastic pancreatic islet and insulin ininsulin sensitivity in obesity
Resveratrol action in the duodenum and the regulation of insulin sensitivity
Comparing the correlation of measures of insulin sensitivity in youth.
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance
Obesity, immunomodulation and chronic kidney disease
Ileal transposition controls diabetes as well as modified duodenal jejunal bypass with better lipid lowering in a nonobese rat model of type II diabetes by increasing …
insulin-like action of vanadium compounds in fat cells
Fenretinide Induces Ubiquitin‐Dependent Proteasomal Degradation of Stearoyl‐CoA Desaturase in Human Retinal Pigment Epithelial Cells
Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3-L1 adipocytes
The insulin-sensitizing role of the fat derived hormone adiponectin
Abrogation of hyperosmotic impairment of insulin signaling by a novel class of 1, 2-dithiole-3-thiones through the inhibition of S6K1 activation
The effect of manipulation of basal pulsatile insulin on insulin action in Type 2 diabetes
insulin resistance and steatosis in hepatitis C virus infection
The relationship between visfatin and HOMA-IR in hypertensive patients, and the effect of antihypertensive drugs on visfatin and HOMA-IR in hypertensive patients …
Acute glucagon induces postprandial peripheral insulin resistance
Skeletal muscle uncoupling protein‐3 restores upon intervention in the prediabetic and diabetic state: implications for diabetes pathogenesis?
Interplay between FGF21 and insulin action in the liver regulates metabolism
Fat accretion and the regulation of insulin-mediated glycogen synthesis after puberty in rats
Fat cell insulin resistance: an experimental study focusing on molecular mechanisms in type 2 diabetes
Therapeutic approaches to insulin resistance
Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells
Low RIP140 expression partially restores metabolic flexibility in L6 muscle cells treated with high FA
Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum
Poker face no more: cancer recurrence reveals its hand
Disclosing the caffeine dose to be administered that restores insulin sensitivity in prediabetes animal
Are oxidative stress− activated signaling pathways mediators of insulin resistance and β-cell dysfunction?
Treatment with intravenous insulin followed by continuous subcutaneous insulin infusion improves glycaemic control in severely resistant type 2 diabetic patients.(Key …
Periodontal therapy: a useful adjunct to improve glycemic control
In human adipocytes exposed to high glucose and insulin levels, IRS-1 displays altered phosphorylation and may be targeted for degradation
Protective effect of aspirin in relation to IGF-1 in streptozotocin induced type-II diabetic rats
Apocynin, an NADPH Oxidase Inhibitor, Prevents Hepatic and Peripheral insulin Resistance Induced by Short-Term Lipid Infusion
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
DiaMedica to Deliver Poster Presentation at World Conference on Clinical Pharmacology and Therapeutics
Lipid disorders in diabetes mellitus and current management
insulin sensitivity: measurements in the whole body and in isolated tissues
Cation-induced restoration of insulin action in insulin-desensitized HTC cells
Potential of surgery for curing type 2 diabetes mellitus
Neutralization of tumor necrosis factor reverses age-induced impairment of insulin responsiveness in skeletal muscle of Sprague-Dawley rats
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Diabetes: An Unfolding Story
Obesity surgery may cure diabetes in nonobese patients
Clinical management strategies for type 2 diabetes
Combination therapy with acipimox enhances the effect of growth hormone treatment on linear body growth in the normal and small-for-gestational-age rat
Induction of laminitis by prolonged hyperinsulinaemia in clinically normal ponies
LMO4 is Required for Central Leptin Control of Fat Metabolism and insulin sensitivity.
insulin sensitizing effects of oligomannuronate-chromium (III) complexes in C2C12 skeletal muscle cells
Angiotensin II receptor blocker ameliorates stress-induced adipose tissue inflammation and insulin resistance
Anti-diabetic effects of benfotiamine on an animal model of type 2 diabetes mellitus
Metabolic flexibility in the development of insulin resistance and type 2 diabetes: effects of lifestyle
Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet–fed mice
Modulation of insulin resistance by PUFA in metabolic tissues
SH2B1 Regulates insulin sensitivity and Glucose Homeostasis by Multiple Mechanisms.
Hyperinsulin sensitivity to insulin during remissions in cyclosporin-treated IDDM patients
Effect of antioxidant treatment on some indicators of obesity-induced changes in insulin sensitivity and beta-cell function in New Zealand white rabbits.
Factors in serum from type 2 diabetes patients can cause cellular insulin resistance.
Tadalafil ameliorates metabolic syndrome-induced alterations in visceral adipose tissue and liver: an experimental study in the rabbit
Manipulation of the insulin-like growth factor 1 receptor on the vascular endothelium: the effect on whole body and endothelial specific insulin sensitivity
Angiotensin II–induced insulin resistance is associated with enhanced insulin signaling
EFFECT OF ASPIRIN PRETREATMENT IN STREPTOZOTOCINE INDUCED TYPE-II DIABETIC RATS
Inflammatory cytokines, adiponectin, insulin resistance and metabolic control after periodontal intervention in patients with type 2 diabetes and chronic periodontitis
Resveratrol improves insulin resistance of catch-up growth by increasing mitochondrial complexes and antioxidant function in skeletal muscle
The FXR agonist obeticholic acid normalizes lipid droplet and triglyceride handling in visceral adipose tissue preadipocytes from a non-genomic rabbit model of …
Sex differences in skeletal muscle Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) levels: A cross-sectional study
N-3 Fatty Acids Preserve insulin sensitivity In Vivo in a PPARα-Dependent Manner
Bone marrow stem cell transplant into intra-bone cavity prevents type 2 diabetes: role of heme oxygenase-adiponectin
Dehydroepiandrosterone levels in Type 2 diabetes
Effects of Exercise and Elevated Fatty Acid Availability on Muscle Lipid Metabolism and insulin sensitivity.
insulin sensitivity and nutrient utilisation in skeletal muscle.
Central Leptin, But Not Central insulin, Attenuates the Decrease of Adiponectin Concentrations and Increases insulin sensitivity in Streptozotocin (STZ)-Induced …
Sirtuin 2 in hypothalamus: an emerging target in insulin resistance?
Leucine-induced Impairment of insulin sensitivity in Skeletal Muscle of Healthy Rats is Reversible
Reversible insulin sensitivity in Grizzly Bears (Ursus Arctos Horribilis): The Roles of Cell Autonomous and Exogenous Factors in Seasonal Glucose Metabolism
N-stearoylethanolamine improves indicators of insulin resistance development under high-fat diet overload
Heat shock proteins induction reduces stress kinases activation, potentially improving insulin signalling in monocytes from obese subjects
Attenuation of Hepatic Leptin Signalling Leads to Improved Glucose Tolerance.
Postprandial Free Fatty Acids (FFA) Metabolism Early in the Natural History of Type 2 Diabetes Mellitus (DM2)
Ligand Binding Site AND Activity Correlations BY Hydrogen/Deuterium Exchange Mass Spectrometry
Natural killer T cells
DOES ASPIRIN PRETREATMENT PREVENT DIABETES IN RATS?
Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinase
Genetic evidence points to an osteocalcin‐independent influence of osteoblasts on energy metabolism
Macrophage migration inhibitory factor deficiency ameliorates high-fat diet induced insulin resistance in mice with reduced adipose inflammation and hepatic …
Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans
Is skeletal muscle mitochondrial dysfunction a cause or an indirect consequence of insulin resistance in humans?
Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice
Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo
Diabetes: A fish story
Identification of a new JNK inhibitor targeting the JNK-JIP interaction site
Effects of insulin resistance on substrate utilization during exercise in overweight women
The kidney: an unwilling accomplice in syndrome X
Childhood obesity and insulin resistance in a Yucatan mini-piglet model: putative roles of IGF-1 and muscle PPARs in adipose tissue activity and development
Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis
Phosphorylation of IRS Proteins: Yin‐Yang Regulation of insulin Signaling
T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor γ binding properties
Osteopontin in obesity-associated adipose tissue inflammation and insulin resistance and its interaction with monocyte chemoattractant protein-1
c-Jun N-terminal kinase 1/2 activation by tumor necrosis factor-α induces insulin resistance in human visceral but not subcutaneous adipocytes: reversal by liver X …
Generation, validation and humanisation of a novel insulin resistant cell model
Effects of inhibition of the renin‐angiotensin system on the cardiovascular actions of insulin
The role of adenosine in insulin action coupling in rat adipocytes
The role of diet and nutrient composition in nonalcoholic fatty liver disease
Ozone exposure triggers insulin resistance through muscle c-Jun N-terminal kinase activation
Impact of periodontitis on the diabetes-related inflammatory status
Tissue specificity on insulin action and resistance: past to recent mechanisms
Ragaglitazar: the pharmacokinetics, pharmacodynamics, and tolerability of a novel dual PPARα and γ agonist in healthy subjects and patients with type 2 diabetes
Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms
Thiazolidinediones in type 2 diabetes mellitus
Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus
Sterols and Terpenoids from Viburnum odoratissimum
Antioxidants: do they have a role in the treatment of insulin resistance?
Proteomic analysis of the palmitate-induced myotube secretome reveals involvement of the annexin A1-formyl peptide receptor 2 (FPR2) pathway in insulin …
Chronic ethanol consumption ameliorates the maturity-onset diabetes-obesity syndrome in CBA mice
Palmitate-activated macrophages confer insulin resistance to muscle cells by a mechanism involving protein kinase C θ and ε
Deterioration of plasticity and metabolic homeostasis in the brain of the UCD-T2DM rat model of naturally occurring type-2 diabetes
Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet‐induced obese mice, independently of weight …
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
Fasting serum insulin and lipid levels in men with epilepsy
Hyperthyroidism causes cardiac dysfunction by mitochondrial impairment and energy depletion
The role of the lipogenic pathway in the development of hepatic steatosis
Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance
Severely impaired insulin signaling in chronic wounds of diabetic ob/ob mice: a potential role of tumor necrosis factor-α
Defining the Importance of Fatty Acid Metabolism in Maintaining Adipocyte Function: A Dissertation
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
The role of s-nitrosothiols and rho-kinase 1 in glucose and lipid metabolism
insulin resistance is a cellular antioxidant defense mechanism
Turning off the inflammatory, but not the metabolic, flames
Inhibitors of the lipid phosphatase SHIP2 discovered by high throughput affinity selection-mass spectrometry screening of combinatorial libraries
Session 8: Mitochondria: from Biochemistry to Medicine Lectures Oral Presentations O8.
Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscle
Impact of alogliptin and pioglitazone on lipid metabolism in islets of prediabetic and diabetic Zucker Diabetic Fatty rats
Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 …
Reflections on inositol (s) for PCOS therapy: steps toward success
Protein tyrosine phosphatases
TOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists
Macrophage-secreted factors induce adipocyte inflammation and insulin resistance
Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply
insulin resistance and response to antiviral therapy in chronic hepatitis C: mechanisms and management
CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes
Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease
Therapeutic roles of peroxisome proliferator–activated receptor agonists
Molecular & genetic factors contributing to insulin resistance in polycystic ovary syndrome.
Differential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistance
The correlation between metabolic syndrome and prostatic growth in patients with benign prostatic hyperplasia
Conjugated linoleic acid may be useful in treating diabetes by controlling body fat and weight gain
Brain signaling systems in the type 2 diabetes and metabolic syndrome: promising target to treat and prevent these diseases
Reciprocal interference between insulin and interferon‐alpha signaling in hepatic cells: A vicious circle of clinical significance?
insulin restores myocardial presynaptic sympathetic neuronal integrity in insulin-resistant diabetic rats
Adipokines mediate inflammation and insulin resistance
Identification of tyrosine phosphatases that dephosphorylate the insulin receptor: a brute force approach based on “substrate-trapping” mutants
Quercetin and quercetin‐3‐O‐glucuronide are equally effective in ameliorating endothelial insulin resistance through inhibition of reactive oxygen species …
Optimization of cardiac metabolism in heart failure
The potential influence of inflammation and insulin resistance on the pathogenesis and treatment of atherosclerosis-related complications in type 2 diabetes
Comparative efficacy of a once-daily controlled-release formulation of glipizide and immediate-release glipizide in patients with NIDDM
Comparison of peripheral metabolic effects of insulin and metformin following severe burn injury
insulin secretion in hypothalamic obesity: Diurnal variation and the effect of naloxone
Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling
Rat amylin-(8—37) enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats
Dietary fat reduction and breast cancer outcome: results from the Women’s Intervention Nutrition Study (WINS)
Poliphenolic-rich extracts from cocoa (Theobroma cacao L.) and cupuassu (Theobroma grandiflorum Willd. Ex Spreng. K. Shum) liquors: A comparison of metabolic …
Differential effects of calorie restriction and exercise on the adipose transcriptome in diet-induced obese mice
Squaric acids: a new motif for designing inhibitors of protein tyrosine phosphatases
Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes
Age-Appropriate Obesity Treatment
FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival
Gene and Cell Therapies for Diabetes Mellitus
What we talk about when we talk about fat
Chemerin induces insulin resistance in rat cardiomyocytes in part through the ERK1/2 signaling pathway
The role of JNK proteins in metabolism
insulin resistance in the offspring of parents with type 2 diabetes
Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice
A low carbohydrate Mediterranean diet improves cardiovascular risk factors and diabetes control among overweight patients with type 2 diabetes mellitus: a 1‐year …
Antioxidants in diabetic complications and insulin resistance
Contribution of TNF-α to Obesity-Associated insulin Resistance
Fish oil and argan oil intake differently modulate insulin resistance and glucose intolerance in a rat model of dietary-induced obesity
Aetiology of non-insulin dependent diabetes
Contribution of salt intake to insulin resistance associated with hypertension
NLRP3 at the interface of metabolism and inflammation
The critical role of metabolic pathways in aging
Endothelial dysfunction in (pre) diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes
Regulation of Skeletal Muscle insulin Action by SIRT1 and STAT3
The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics
Effective surgical treatment of diabetes for the obese patient
Mechanism and management of AKT inhibitor-induced hyperglycemia
Toll-like receptor 4-induced endoplasmic reticulum stress contributes to impairment of vasodilator action of insulin
AMPK activators–potential therapeutics for metabolic and other diseases
The role of insulin resistance in peripheral vascular disease
Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis
Novel concepts in insulin regulation of hepatic gluconeogenesis
Effect of high-fat diet on metabolic indices, cognition, and neuronal physiology in aging F344 rats
When to use insulin in the maturity onset diabetic.
Quantum medicine update
Molecular targets related to inflammation and insulin resistance and potential interventions
the treatment of non‐alcoholic steatohepatitis with thiazolidinediones
Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes
Histone deacetylase HDAC8 promotes insulin resistance and β-catenin activation in NAFLD-associated hepatocellular carcinoma
The IGF-1 receptor and regulation of nitric oxide bioavailability and insulin signalling in the endothelium
Novel in vivo studies on the effect of ethanolic stick cherries extract in diabetes management
Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency: a randomized, controlled …
Macrophage HIF-2α ameliorates adipose tissue inflammation and insulin resistance in obesity
Leptin regulation of the immune response and the immunodeficiency of malnutrition1
Antihyperglycemic effects of total flavonoids from Polygonatum odoratum in STZ and alloxan-induced diabetic rats
Type 2 diabetes mellitus: update on diagnosis, pathophysiology, and treatment
The hypoglycemic effect of pumpkin seeds, Trigonelline (TRG), Nicotinic acid (NA), and D-Chiro-inositol (DCI) in controlling glycemic levels in diabetes mellitus
Peroxisome proliferator-activated receptors and hepatitis C virus-induced insulin resistance
Systematic review: Preventive and therapeutic applications of metformin in liver disease
Chemokine expression in inflamed adipose tissue is mainly mediated by NF-κB
Obesity, inflammation, and the potential application of pharmaconutrition
Diabetes and gum disease: the diabolic duo
Kinetics and molecular docking studies of pimarane-type diterpenes as protein tyrosine phosphatase (PTP1B) inhibitors from Aralia continentalis roots
Restoring HSP70 deficiencies improves glucose tolerance in diabetic monkeys
Eosinophils reduce chronic inflammation in adipose tissue by secreting Th2 cytokines and promoting M2 macrophages polarization
Process Development on the Enantioselective Enzymatic Hydrolysis of S-Ethyl 2-Ethoxy-3-(4-hydroxyphenyl)propanoate
The beta cell function in NIDDM patients with secondary failure
Inflammatory mechanisms in obesity
Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus
Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys
Lipotoxicity versus adipotoxicity—the deleterious effects of adipose tissue on beta cells in the pathogenesis of type 2 diabetes
Glucose Uptake and Its Consequence on Cardiomyocyte Function
n− 3 Fatty acids and the metabolic syndrome
Mechanisms in endocrinology: Non-alcoholic fatty liver disease in common endocrine disorders
New hope for type 2 diabetics: Targeting insulin resistance through the immune modulation of stem cells
Therapeutic targets of brain insulin resistance in sporadic Alzheimer’s disease
Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects
Troxerutin reverses fibrotic changes in the myocardium of high-fat high-fructose diet-fed mice
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes
Angiotensin-converting enzyme inhibition delays onset of glucosuria with regression of renal injuries in genetic rat model of non-insulin-dependent diabetes mellitus
Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with …
Tissue availability of insulin-like growth factor I is inversely related to insulin resistance in essential hypertension: effects of angiotensin converting enzyme inhibition
Targeting host factors: a novel rationale for the management of hepatitis C virus
Use of mouse models in studying type 2 diabetes mellitus
Cardiovascular prevention in type 2 diabetes mellitus patients: the role of oral glucose-lowering agents
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer’s disease
insulin relaxes bladder via PI3K/AKT/eNOS pathway activation in mucosa: unfolded protein response‐dependent insulin resistance as a cause of obesity‐associated …
Overexpression of vesicle-associated membrane protein (VAMP) 3, but not VAMP2, protects glucose transporter (GLUT) 4 protein translocation in an in vitro …
Drug-induced disorders of glucose tolerance
Pharmacological activation of thyroid hormone receptors elicits a functional conversion of white to brown fat
Drug-induced hyperglycaemia and diabetes
Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues
Palmitate-Activated Macrophages Confer insulin Resistance to Muscle Cells by a Mechanism Involving
Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice
Use of insulin sensitizers in NASH
The angiotensin-melatonin axis
Improving glucose metabolism with resveratrol in a swine model of metabolic syndrome through alteration of signaling pathways in the liver and skeletal muscle
The emerging role of thiazolidinediones in the treatment of diabetes-mellitus and related disorders
Sodium glucose co-transporter 2 (SGLT2) inhibitors as potential antidiabetic agents
Development of leptin resistance in rat soleus muscle in response to high-fat diets
Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance
Metabolic syndrome in HD patients: association with body composition, nutritional status, inflammation and serum iron
The Relationship Among Obesity, Inflammation, and insulin Resistance
Phenylmethimazole blocks palmitate-mediated induction of inflammatory cytokine pathways in 3T3L1 adipocytes and RAW 264.7 macrophages
Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects
Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet–induced obese rats
How metabolism generates signals during innate immunity and inflammation
Targeting PGC-1α to control energy homeostasis
Different adipose depots: their role in the development of metabolic syndrome and mitochondrial response to hypolipidemic agents
The overexpression of carnitine palmitoyl transferase1 and its influence on the lipid metabolism of rat hepatocytes
Cardiotrophin-1 is a key regulator of glucose and lipid metabolism
Sulfonylureas in NIDDM
Pharmacological properties of the central antihypertensive agent, moxonidine
Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer’s disease
Use of metformin in the treatment of polycystic ovary syndrome
The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases
The intersection of inflammation, insulin resistance and ageing: implications for the study of molecular signalling pathways in horses
Reactive oxygen species play a causal role in multiple forms of insulin resistance
Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes
Effectiveness of telmisartan as an adjunct to metformin in treating type II diabetes mellitus in rats
Female rats are relatively more sensitive to reduced lipid versus reduced carbohydrate availability
The role of adiponectin in reproduction: from polycystic ovary syndrome to assisted reproduction
My βIG Fat Math Model: β-Cell Compensation and Type 2 Diabetes
Antihyperglycaemic properties of the ethyl acetate extract of Dennettia tripetala in diabetic rats
Free fatty acid-induced insulin resistance in the obese is not prevented by rosiglitazone treatment
Obesity and adipose tissue expansion in Ossabaw swine
Biphasic effect of alcohol intake on the development of fatty liver disease
insulin resistance is a major determinant of sustained virological response in genotype 1 chronic hepatitis C patients receiving peginterferon α‐2b plus ribavirin
insulin-like growth factors and their binding proteins: biological actions
Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?
CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocyte cultures
Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to reduced mobility and overweight in mice
Oral administration of immunoglobulin G‐enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells
Bariatric surgery decreases monocyte-platelet aggregates in blood: a pilot study
Nonalcoholic fatty liver disease: the potential role of nutritional management
POSTERS: CLINICAL THERAPEUTICS/NEW TECHNOLOGY-TREATMENT OF insulin RESISTANCE
A study of the biological activities of Avena sativa extracts
Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes
insulin-like growth factor-related proteins and diabetic complications
Effect of lithium on plasma glucose, insulin and glucagon in normal and streptozotocin-diabetic rats: role of glucagon in the hyperglycaemic response.
Novel “second-generation” approaches for the control of type 2 diabetes
Reversal of obesity-induced hypertriglyceridemia by (R)-α-lipoic acid in ZDF (fa/fa) rats
Anti-diabetic effects of polysaccharides from Opuntia monacantha cladode in normal and streptozotocin-induced diabetic rats
MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance
NPY signalling in early osteoblasts controls glucose homeostasis
Pathophysiological Relevance of PPAR to Osteoarthritis: From the Control of Inflammation to Cartilage Protection?
VEGF-B Blockade in muscle endothelium: a potential barrier to type 2 diabetes
Nutritional and hormonal modulation of adiponectin and its receptors adipoR1 and adipoR2
TNF-α and adipocyte biology
Red Light Therapy for Diabetes and insulin Resistance
George Q. Li,” Antony Kam,” Ka H. Wong,” Xian Zhou,’Eshaifol A. Omar,’Ali Alqahtani,” Kong M. Li,”
Role of T cells in malnutrition and obesity
Amino acids and mTORC1: from lysosomes to disease
Pathogenesis of insulin resistance in metabolic obesity
Anti-diabetic activity of Vaccinium bracteatum Thunb. leaves’ polysaccharide in STZ-induced diabetic mice
12-and 15-lipoxygenases in adipose tissue inflammation
insulin Action at the Molecular Level: Facts and Speculations
Adipocyte expression of PU. 1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production
Tissue resident regulatory T cells: novel therapeutic targets for human disease
Computational pharmacokinetics and in vitro-in vivo correlation of anti-diabetic synergistic phyto-composite blend
Ozone exposure triggers insulin resistance through muscle c-Jun N-terminal Kinases (JNKs) activation
Surgery in the treatment of type 2 diabetes mellitus
Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury
Antihyperglycemic effects of the methanol leaf extract of Diaphananthe bidens in normoglycemic and streptozotocin–induced hyperglycemic rats
Critical role of the Src homology 2 (SH2) domain of neuronal SH2B1 in the regulation of body weight and glucose homeostasis in mice
The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions
Regulation of glucose transport and expression of GLUT3 transporters in human circulating mononuclear cells: studies in cells from insulin-dependent diabetic and …
Trauma and hemorrhage-induced acute hepatic insulin resistance: Dominant role of tumor necrosis factor-α
Mechanisms of disease: mitochondrial dysfunction in sensory neuropathy and other complications in diabetes
Lipoxin A4 attenuates obesity-induced adipose inflammation and associated liver and kidney disease
Elevated levels of TWEAK in skeletal muscle promote visceral obesity, insulin resistance, and metabolic dysfunction
p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation …
Carnitine in metabolic disease: potential for pharmacological intervention
Ipragliflozin and other sodium–glucose cotransporter-2 (SGLT2) inhibitors in the treatment of type 2 diabetes: preclinical and clinical data
Metabolic Control by Inflammation and Immunity: Toll-like receptor 4-induced endoplasmic reticulum stress contributes to impairment of vasodilator action of …
Development of Personal UVB Sensor: Detection of Previtamin D Photosynthesis
Implication of mitochondria endoplasmic-reticulum interactions in the control of hepatic metabolism
Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis
Diosgenin, 4-hydroxyisoleucine, and fiber from fenugreek: mechanisms of actions and potential effects on metabolic syndrome
Metformin modulates insulin post-receptor signaling transduction in chronically insulin-treated Heps G2 cells
Effects of physical activity upon the liver
Metabolism and insulin signaling in common metabolic disorders and inherited insulin resistance
A pharmacokinetic and pharmacodynamic study of pioglitazone in a model of induced insulin resistance in normal horses
Effect of Vaccinium bracteatum Thunb. leaves extract on blood glucose and plasma lipid levels in streptozotocin-induced diabetic mice
Effect of growth hormone on carbohydrate and lipid metabolism
High speed development work by preparation of an “in‐hand” library of NMR‐quantified degradation products
A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-transport (SGLT) inhibitors. Systematic review and meta-analysis of …
Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation
Review of the roles of conjugated linoleic acid in health and disease
The pro‐inflammatory environment in recalcitrant diabetic foot wounds
Enhanced fatty acid flux triggered by adiponectin overexpression
Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture
The role of IGF-I in the development of cardiovascular disease in type 2 diabetes mellitus: is prevention possible?
Covalent peroxisome proliferator-activated receptor γ adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions
insulin resistance and the modulation of rat cardiac K+ currents
First Choice of Antihypertensive Therapy
First Choice of Antihypertensive Therapy
Moderate exercise restores pancreatic beta-cell function and autonomic nervous system activity in obese rats induced by high-fat diet
Caffeine reduces TNFα up-regulation in human adipose tissue primary culture
The hypoglycemic effect of Juglans regia leaves aqueous extract in diabetic patients: A first human trial
Type 2 diabetes mellitus in chronic hepatitis C virus infection: risk factor or consequence?
Genetic manipulation of Receptor Interacting Protein (RIP140) uncovers its critical role in the regulation of metabolism, gene expression and insulin signaling …
Current and emerging treatment options in diabetes care
Hypoglycaemic effects of fermented mycelium of Paecilomyces farinosus (G30801) on high-fat fed rats with streptozotocin-induced diabetes
The pleiotropic functions of peroxisome proliferator-activated receptor γ
Therapeutic use of recombinant methionyl human leptin
Zinc transporters, mechanisms of action and therapeutic utility: implications for type 2 diabetes mellitus
Mitochondrial pyruvate import and its effects on homeostasis
Exercise pills: at the starting line
Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2
Diabetes mellitus and periodontal diseases
New progress in adipocytokine research
Metabolomic analyses for atherosclerosis, diabetes, and obesity
Chronic prenatal ethanol exposure increases adiposity and disrupts pancreatic morphology in adult guinea pig offspring
Type 2 diabetes–tuberculosis co-morbidity is associated with diminished circulating levels of IL-20 subfamily of cytokines
Targeting the kidney and glucose excretion with dapagliflozin: preclinical and clinical evidence for SGLT2 inhibition as a new option for treatment of type 2 …
Hormonal control of diabetes type 2 after surgery: Clinical and experimental evaluation
Old drug acquires new target: metformin and Sirt1
Effects of vanadate on glucose production in cultured hepatocytes isolated from rats on high saturated fat diet
Getting rid of JNK
Separation of insulin signaling into distinct GLUT4 translocation and activation steps
Weight-reduction through a low-fat diet causes differential expression of circulating microRNAs in obese C57BL/6 mice
A detailed study on poly cystic ovarian syndrome and it’s treatment with natural products
Cardiometabolic interventions–focus on transcriptional regulators
Angiotensin-Converting Enzyme Inhibition Delays Onset
Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin
The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation
Rescue of fructose-induced metabolic syndrome by antibiotics or faecal transplantation in a rat model of obesity
Possibility of ozone depletion monitoring in conditions of opaque atmosphere using D-dosimeter
Composition and hypoglycemic effect of camel milk in streptozotocin-induced diabetic rats
Apparent induction of partial thymic regeneration in a normal human subject: a case report
Therapeutic perspectives for type 2 diabetes mellitus: molecular and clinical insights
Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress
Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectives
PI3K-Akt-mTOR and MAPK signaling pathways in polycystic ovarian syndrome, uterine leiomyomas and endometriosis: an update
12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response
Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats
Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs
Pancreatic ultrastructural enhancement due to telmisartan plus sitagliptin treatment in diet-induced obese C57BL/6 mice
Protein kinase C: mediator or inhibitor of insulin action?
The effect of 2-month bromocriptine treatment on the activity of the adenylyl cyclase signaling system in the myocardium and testes of rats with type 2 diabetes
Oral hypoglycaemic agents.
Kidney Failure Cause
Diabetes mellitus and inflammatory periodontal diseases
Genomics, nutrition, obesity, and diabetes
Muscular response and adaptation to diabetes mellitus
Tumor necrosis factor α (TNFα) stimulates Map4k4 expression through TNFα receptor 1 signaling to c-Jun and activating transcription factor 2
Drug-induced diabetes mellitus
Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation
Glucose control and integration by the skeleton
Interrelationships between obesity and diabetes
Plasma leptin levels after biliopancreatic diversion: dissociation with body mass index
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
The sirtuin family’s role in aging and age-associated pathologies
Mechanism and Management of AKT Inhibitor-Induced Hyperglycemia
Mediterranean Diet is an Effective Method for Treating Type 2 Diabetes in Adults
Pathophysiological relevance of peroxisome proliferators activated receptors (PPAR) to joint diseases–the pro and con of agonists
Protein tyrosine phosphatase 1B inhibitory activity of alkaloids from Rhizoma Coptidis and their molecular docking studies
Metabolic complications associated with HIV protease inhibitor therapy
Polycystic Ovarian Syndrome: a new perspective
Peripheral and hepatic vein cytokine levels in correlation with non-alcoholic fatty liver disease (NAFLD)-related metabolic, histological, and haemodynamic …
Design, synthesis, and structure− activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal …
Pharmacogenetics of Diabetes
Type 4 Hyperlipoproteinemia: One Theory of Atherogenesis
Anti-inflammatory and antidiabetic roles of PPAR gamma
Twelve weeks of pioglitazone therapy significantly attenuates dysmetabolism and reduces inflammation in continuous ambulatory peritoneal dialysis patients—a …
The nuts and bolts of AGC protein kinases
D‐CHIRO‐INOSITOL FOUND IN MOMORDICA CHARANTIA FRUIT EXTRACT PLAYS A ROLE IN REDUCING BLOOD GLUCOSE IN STREPTOZOTOCIN‐DIABETIC …
insulin receptor substrate (IRS)‐1 regulates murine embryonic stem (mES) cells self‐renewal
Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic β-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein …
Dehydroepiandrosterone stimulates glucose uptake in human and murine adipocytes by inducing GLUT1 and GLUT4 translocation to the plasma membrane
Rosiglitazone reverses increased duodenal inhibitory response in spontaneously hypertensive rats
The Medicinal Plant Sutherlandia Frutescens Regulates Gene Expression to Reverse insulin Resistace in Rats
Momordica charantia and type 2 diabetes: from in vitro to human studies
Thesis, antithesis, and synthesis in periodontal and systemic interlink
Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications
Hepatitis C and steatosis
Therapeutic potential of intravenously administered mesenchymal stem cells in diet-induced obesity
Rhesus macaques develop metabolic syndrome with reversible vascular dysfunction responsive to pioglitazone
The effect of scaling and root planing on glycaemic control, periodontal status and gingival crevicular fluid TNF-α levels in an Indian population-to reveal the …
Cellular models for the analysis of signaling by protein kinase B and the forkhead transcription factor FKHR (Foxo1a)
Secondary Diabetes: Drug Induced Diabetes
Metal-based anti-diabetic drugs: advances and challenges
Extrahepatic morbidity and mortality of chronic hepatitis C
Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated
Histone deacetylase HDAC8 promotes insulin resistance and-catenin
PPAR ligands for the treatment of insulin resistance
P2-455: The neurocognitive effects of donepezil on visual short-term memory capacity following 24 Hours of sleep deprivation
Polycystic ovarian syndrome: a new perspective
Inhibition of Vascular Endothelial Growth Factor Signaling Stimulates Erythropoiesis and Sensitizes Hepatic insulin Signaling Through Activation of Hepatic …
Periodontitis and diabetes—a complex relationship
Taurine in health and diseases: consistent evidence from experimental and epidemiological studies
Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase–dependent pathway that is impaired with obesity
Nigella sativa oil potentiates the effects of pioglitazone on long term alloxan-induced diabetic rats
Ecology then and Now
Thiazolidinedione therapy in a patient with diabetes after cardiac transplantation
Soybean and processed soy foods ingredients, and their role in cardiometabolic risk prevention
Role of Leucine in Modulation of Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes
Plasma phospholipids n‐3 polyunsaturated fatty acid is associated with metabolic syndrome
Endocrine and Metabolic Dysfunction during Aging and Senescence: MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide …
insulin resistance and progression of heart failure in the older adult
N-3 polyunsaturated fatty acids and inflammation in obesity: local effect and systemic benefit
Macrophage peroxisome proliferator activated receptor γ as a therapeutic target to combat type 2 diabetes
Nonalcoholic fatty liver disease: molecular pathways and therapeutic strategies
Advanced proteomics procedure as a detection tool for predictive screening in type 2 pre-Diabetes
Exercise-induced recovery of skeletal muscle insulin response is independent of adiponectin response in high-fat fed rodents
Redox implications in adipose tissue (dys) function—a new look at old acquaintances
Modulatory effects of diosgenin on attenuating the key enzymes activities of carbohydrate metabolism and glycogen content in streptozotocin-induced diabetic rats
Role of MAP4K4 Signaling in Adipocyte and Macrophage Derived Inflammation: A Dissertation
Freedom from Disease: The Breakthrough Approach to Preventing Cancer, Heart Disease, Alzheimer’s, and Depression by Controlling insulin
Effects of age and acute submaximal exercise on inflammatory cytokines, cortisol, insulin, heat shock proteins and skeletal muscle mediators of energy homeostasis in …
Metformin and metabolic diseases: a focus on hepatic aspects
The role of PtdIns (4, 5) P2 and its regulatory proteins in the development of insulin resistance in cell culture models
Pharmacological and Pharmaceutical Developments on Fagopyrum Tataricum
THE HEPATITIS CVirus AND DIABETES MELLITUS ASSOCIATION: CHARACTERIZATION AND STUDIES OF RISK FACTORS, MECHANISMS, IMPLICATIONS AND …
PMI 5011 regulates the ubiquitin proteasome system in skeletal muscle
A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin‐targeted keratinocyte grafts
The effects of potassium ions and denervation on protein synthesis and the transport of amino acids in muscle
The role of WNT10B in physiology and disease
Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy are associated with serum concentrations of leptin
Regulation of carbohydrate metabolism by the farnesoid X receptor
Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease
Effects of transplantation and resection of a radiation-induced rat insulinoma on glucose homeostasis and the endocrine pancreas
Endoplasmic reticulum stress and Nox-mediated reactive oxygen species signaling in the peripheral vasculature: potential role in hypertension
Status of association studies linking diabetes mellitus and periodontal disease in India
Critical Role of the Src Homology 2 (SH2) Domain of Neuronal SH2B1 in the Regulation of Body Weight and Glucose Homeostasis…
The effect of a soy protein diet on attenuation of obesity-related pathologies in obese Zucker rats.
Phosphorylation of insulin receptor substrate-1 in development of muscle insulin resistance
What causes equine laminitis
Pharmaceutical salts and cocrystals involving amino acids: a brief structural overview of the state-of-art
Nuclear receptors: novel therapeutic targets for the treatment and prevention of atherosclerosis
IKKβ and the anti-adipogenic effect of platelet-derived growth factor in human abdominal subcutaneous preadipocytes
The role of sterol 12α-hydroxylase (Cyp8b1) in glucose homeostasis
Suppression of nuclear factor-κB and stimulation of inhibitor κB by troglitazone: evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the …
Repetitive DNA elements as mediators of genomic change in response to environmental cues
Stop Inflammation Now!
Chemical modulators working at pharmacological interface of target proteins
Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity
Biocatalysis: Synthesis of key intermediates for development of pharmaceuticals
Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis
Maassen3, A. Edo Meinders1
Peroxisome proliferator-activated receptor-γ as a therapeutic target for hepatic fibrosis: from bench to bedside
Regulation of semicarbazide-sensitive amine oxidase expression by tumor necrosis factor-α in adipocytes: Functional consequences on glucose transport
Hyperinsulinemia Tends to Induce Growth Without Growth Hormone in Children with Brain Tumors After Neurosurgery
Effect of scaling and root planing on serum interleukin-10 levels and glycemic control in chronic periodontitis and type 2 diabetes mellitus
Ginkgolide C suppresses adipogenesis in 3T3-L1 adipocytes via the AMPK signaling pathway
Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment
Angiotensin II receptors and drug discovery in cardiovascular disease
Effect of weight-reduction in obese mice lacking toll-like receptor 5 and C57BL/6 mice fed a low-fat diet
Clinical Pharmacology of Sulfonylureas
CŞ BASICS
Strengthening innate immunological weaponry against carcinogenesis
Overnutrition, mTOR signaling, and cardiovascular diseases
Heat Shock Proteins: Treating Metabolic Disease by Turning up the Heat
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
Robust control in biology: From genes to cells to systems
Factors affecting insulin-stimulated in vitro glucose oxidation in rat epididymal adipocytes
The Endoplasmic reticulum and insulin signalling in adipocytes
Diabetes: 8 strategies to put into practice
Sleep apnea syndrome: implications on cardiovascular diseases
Synthesis and characterization of insulin receptor partial agonists as a route to improved diabetes therapy
c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges
Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat
New treatments for chronic hepatitis C
Identification of Biomarkers for Beta Cell Failure as Detection Tools for Predictive Screening in Type 2 Pre-diabetes
Consequences of chronic inflammation in peritoneal dialysis
Identification of a novel AS160 splice variant that regulates GLUT4 translocation and glucose-uptake in rat muscle cells
Screening in Type 2 Pre-diabetes
The Mechanisms Underlying Free Fatty Acid-induced Hepatic insulin Resistance
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner
Covalent peroxisome proliferator-activated receptorγ binding by nitro-fatty acids: Endogenous ligands act as selective modulators
Review Article Different Adipose Depots: Their Role in the Development of Metabolic Syndrome and Mitochondrial Response to Hypolipidemic Agents.
Diabetes and Its Association With Periodontal Tissues
Development and validation of a high-precision capillary electrophoresis method for main component assay of ragaglitazar
Polycystic Ovary Syndrome, Obesity and insulin Resistance
JNK pathway signaling: a novel and smarter therapeutic targets for various biological diseases
Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive rat
Beta-adrenoreceptor modulation of metabolic, endocrine and immunologic function during critical illness
Coffee and type 2 diabetes risk
Network analysis: a new approach to study endocrine disorders
Metabolic and physiological studies in a rat model of type 2 diabetes
Protective effects of SP600125 in a diet-induced rat model of non-alcoholic steatohepatitis
Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor α/γ agonist ragaglitazar
Feeding high oleic acid Canola oil or olive oil alters inflammation, insulin resistance and lipid metabolism in a rodent model of diet induced obesity
Obesity-associated interleukin-6 contributes to hepatic insulin resistance in mice
Role of PKB/Akt in liver diseases
The race for interferon‐free HCV therapies: a snapshot by the spring of 2012
Metformin inhibits the growth of nasopharyngeal carcinoma cells and sensitizes the cells to radiation via inhibition of the DNA damage repair pathway
Mouse Models to Study Metformin Effects in Carcinogenesis
Lack of Angiopoietin‐Like‐2 Expression Limits the Metabolic Stress Induced by a High‐Fat Diet and Maintains Endothelial Function in Mice
Molecular Mechanisms Involved in Inflammation and insulin Resistance in Chronic Diseases and Possible Interventions
Glycerolipid metabolism and signaling in health and disease
Adaptive enzyme responses in adipose tissue of obese hyperglycemic mice
Transcriptional regulation of adipose insulin resistance
The role of adiponectin and the adipocyte in energy metabolism and inflammation
Development of thiadiazole as an antidiabetic agent-a review
Caenorhabditis elegans, an invertebrate model organism for biomedical research
Adipokines and redox signaling: impact on fatty liver disease
The liver in metabolic syndrome
Management of diabetic ketoacidosis
Correlative studies on the effects of obesity, diabetes and hypertension on gene expression in omental adipose tissue of obese women
Imidazoline receptors in insulin signaling and metabolic regulation
Caenorhabditiselegans, An Invertebrate Model Organism for Biomedical Research
The effects of pharmacological management of depression on HbA1c in type 2 diabetes
The polycystic ovary syndrome–challenges and opportunities in adolescent medicine
Histone Deacetylase 8 Promotes insulin Resistance and β-catenin Activation in NAFLD-associated Hepatocellular Carcinoma
Reduction of hepatic steatosis in rats and mice after treatment with a liver‐targeted thyroid hormone receptor agonist
Cardiovascular mortality and morbidity in dialysis patients
Citrus ichangensis peel extract exhibits anti-metabolic disorder effects by the inhibition of PPAR and LXR signaling in high-fat diet-induced C57BL/6 mouse
Cardiovascular disease in renal transplant recipients
FEDERICO II
Antihepatotoxic activity of a quantified Desmodium adscendens decoction and D-pinitol against chemically-induced liver damage in rats
ATP non-competitive Ser/Thr kinase inhibitors as potential anticancer agents
The clinical role of hepatocyte and commensal-probiotic cell physiology in the successful detoxification of carcinogenic toxicants
Endocrine aspects of pulmonary hypertension
Studies on the mechanisms of action and physiological relevance of SOCS proteins
13 Olive Oil in Metabolic
Managing diabetes and periodontal disease.
Upstream molecular signaling pathways of p27 (Kip1) expression in human breast cancer cells in vitro: differential effects of 4-hydroxytamoxifen and …
Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly
The outliers become a stampede as immunometabolism reaches a tipping point
Cardiovascular risk factors following renal transplant
Belinda P. Childs, ARNP, MN, CDE, BC-ADM, is a diabetes nurse spe-cialist
Collaboratively constructed contradictory accounts: online organizational narratives
Protein–Protein Interactions: A Simple Strategy to Identify Binding Sites and Peptide Antagonists
Does Mycobacterium avium subspecies paratuberculosis cause Crohn’s
Metabolic hormones in bariatric surgery and reward behaviour
STUDIES ON THE REGULATION OF FGF21 GENE EXPRESSION BY (R)-α-LIPOIC ACID: MECHANISTIC INSIGHT INTO THE LIPID LOWERING PROPERTIES OF A …
Protein-protein interactions: network analysis and applications in drug discovery
Outcomes of acute myocardial infarction in Type 2 diabetic Yemeni patients using different methods of treatment
Non-systemic drugs: a critical review
Mitochondrial energy failure in the eye induces loss of visual acuity in early metabolic syndrome: A novel therapeutic target
Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and …
Gene therapy technology applied to disorders of glucose metabolism: promise, achievements, and prospects
Effect of nutrition education intervention and lifestyle behaviors on management of type 2 diabetes mellitus in Mwanza city, Tanzania
Rheumatoid arthritis: an autoimmune disease with female preponderance and cardiovascular risk equivalent to diabetes mellitus: role of cardiovascular magnetic …
Inhibitory Effect of Central Leptin on Hepatic Glucose Production in Streptozotocin (STZ)-Induced Diabetic Rats
An association of boswellia, betaine and myo-inositol (Eumastós®) in the treatment of mammographic breast density: a randomized, double-blind study
Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48−/−Lepob/ob mice devoid of ApoE or Ldlr
Therapeutical procedures to treat the metabolic syndrome in humans and animal models
SCIENTIFIC SESSION ABSTRACTS
Integrated characterization of cellular physiology underlying hepatic metabolism
Metabolism and fatty acid profile in fat and lean rainbow trout lines fed with vegetable oil: effect of carbohydrates
Cardiovascular Cells
The Intricate Role of Adipokines in Immune-Mediated Diseases
Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways
Feast or famine: Altered maternal nutrition and disease risk in offspring
The Gut Microbiome–Clinical Implications for the Practicing Gastroenterologist
The endothelial response to diabetes reveals a protective role for galectin-3 in diabetic vasculopathy and glucose metabolism
Energy Balance and Cancer Risk: Metabolic and Molecular Studies
Francesco Negro, Daniel Forton, 2 Antonio Craxì, 3 Mark S Sulkowski, 4 Jordan J. Feld, 5 Michael
Discovery of peptides with balanced glucagon antagonism and GLP-1 agonism, supported by an investigation of their molecular basis for such action
Curves: Permanent Results Without Permanent Dieting
15 Obesity and Type 2 Diabetes
NON-PHARMACEUTICAL INTERVENTION OPTIONS FOR TYPE 2 DIABETES
The Endocrine System
dLipin- A Link Between Lipid Metabolism, Glucose Homeostasis and Growth in Drosophila melanogaster
Role of the adipocyte in metabolism and endocrine function
Chronic prenatal ethanol exposure produces neurobehavioural and metabolic dysfunction in guinea pig offspring
Skeletal and Cardiac Muscle Energy Metabolism in Health and Disease
9 Mineral Deficiencies
Mechanisms of Beta Cell Dysfunction and Application of Glp-1 Mimetics in Feline Diabetes Mellitus
Regulation of the Mechanistic Target of Rapamycin by Cellular Stress.
Negative regulation of the inflammasome: keeping inflammation under control
Targeting mitochondrial function in diabetic nephropathy
Developing C. elegans as a model to study Type 2 Diabetes Mellitus
In Vivo Screening for Secreted Proteins That Modulate Glucose Handling Identifies Interleukin-6 Family Members as Potent Hypoglycemic Agents
Terminal Modulator Protein (CTMP) regulates mitochondrial dynamics. PLoS One 4, e5471. Parone, PA, Da Cruz, S., Tondera, D., Mattenberger, Y., James, DI …
First National Congress on Nutritional Medicine of the Dutch Nutraceutical Association
The effect of conjugated linoleic acid (CLA) on sow and litter immune status and performance
Proposed mechanisms underlining the potential effects of Staphylococcal superantigens on the development of type two diabetes
Is there an embryopathy associated with first‐trimester exposure to angiotensin‐converting enzyme inhibitors and angiotensin receptor antagonists? A critical review …
The Regulation of Net Hepatic Glucose Uptake in vivo
STUDIES ON THE MECHANISMS OF ACTION AND PHYSIOLOGICAL RELEVANCE OF SOCS PROTEINS
Achieving control of diabetic risk factors in primary care settings
Hunger Free Forever: The New Science of Appetite Control
Sweeteners and metabolic disorders
Molecular aspects of alcohol metabolism: transcription factors involved in early ethanol-induced liver injury
Jaypee Gold Standard Mini Atlas Series®: Diabetes
TCF7L2 overexpression and type 2 diabetes: Dissecting the function of TCF7L2 as a regulator of glucose metabolism
Multi-level regulation of argininosuccinate synthase: Significance for endothelial nitric oxide production
Islet antibodies, autoimmunity, and β-cell function
Continuous positive airway pressure therapy for sleep disordered breathing in adults
GLP-1 CellBead Therapy for the Prevention of Left Ventricular Dysfunction in Pigs
Promoting and maintaining physical activity in people with type 2 diabetes
The Metabolic Syndrome and associated components among African women
insulinoma
Oxidative stress and inflammation as therapeutic targets of high-fat diet-induced metabolic diseases
Cardiopulmonary and Quality of Life Responses of Individuals with Type 2 Diabetes to Therapeutic Excercises
AMP-activated protein kinase, Sirtuin 1, and p53 interactions in HEPG2 cells
Racial/ethnic variation in clinical presentation, treatment, and survival among breast cancer patients under age 35
The roles of ATF3 in stress-regulated signal transduction and cell death in pancreatic beta-cells
The Role of the Cannabinoid Receptor Type 1 in Energy Balance, Glucose Metabolism, and Thermogenesis
Phytanic acid alpha-oxidation, new insights into an old problem: a review
Identification of bioactive compounds in wheat
Diabetic macular oedema: the role of steroids and VEGF
The Implications of CD36 Alteration on Rodent Skeletal Muscle Lipid Metabolism
Adipose-derived Signals Induce Hyperplasia of the Mammary Epithelium in Response to 10e12z Conjugated Linoleic Acid Initiated Adipose Dysfunction
Roles of ABCG5 ABCG8 cholesterol transporter in lipid homeostasis
MEDICINE, SÃO PAULO, BRAZIL, OCTOBER 8–12, 2014
Metabolic aspects of obesity
Forkhead at the Crossroads of Cancer and Healthy Lifespan
Metabolic Acidosis of Chronic Kidney Disease
The Coconut Diet: The Secret Ingredient that Helps You Lose Weight While You Eat Your Favorite Foods
Skeletal muscle fat infiltration is reversed by dietary fish oil in an animal model of colorectal cancer receiving irinotecan and 5-fluorouracil
Dialed in
Effects of chronic hyperglycemia on gene expression in streptozotocin-induced diabetic rats
CHROMIUM SUPPLEMENTATION IN MANAGEMENT OF TYPE 2 DIABETES AMONG PATIENTS ATTENDING THIKA LEVEL 5 HOSPITAL, KENYA: A …
Regulation of adipocyte and osteoblast differentiation by Wnt signaling
Knowledge, opinions and practice behaviors of North Carolina endocrinologists’ and internists’ regarding periodontal disease and diabetes
Unraveling the molecular physiology of the β-cell: genome wide analysis of binding sites for the transcription factor PDX1
Cerebral blood flow and glucose metabolism in ischemic stroke: multimodal imaging investigations in a clinically relevant rat model
Health promoting factors from milk of cows fed green plant material-The role of phytanic acid
Fatty liver syndrome in mink-causes and metabolic consequences
4 Caloric Intake: Sources, Deficiencies
List of Abstracts
Effect of dietary polyunsaturated fatty acids on rat tissue oxylipin profiles
Multi-modal Analysis of Metabolic Enzyme Disruption in Adipocytes
The Design, Characterization, and Efficacy of Protease-Resistant Therapeutic Peptides
MEDICAL LIBRARY
Discovery and Characterization of Inflammation-Induced Electrophilic Fatty Acid Derivatives
Becoming Vegan: The Complete Reference to Plant-Base Nutrition
12 CE in impurity profiling of drugs
An Investigation of the Relationship Between Dermal Stresses and Foot Ground Stresses in Diabetic Patients
Inhibition of Class I HDACs Blunts Cardiac Hypertrophy via TSC2-Dependent mTOR Repression
In vitro screening assay using the murine pre-adipocyte cell line 3T3-L1 to study anti-obesogenic activities of cyanobacterial compounds
HEALTH SEEKING BEHAVIOUR AND PATTERN OF ADHERENCE TO TREATMENT AMONG PATIENTS WITH TYPE-2 DIABETES MELLITUS IN CENTRAL …
Effects of vitamin A deficiency on retinoid and energy metabolism in liver and white adipose tissue
CD64-mediated specific elimination of M1-polarized macrophages: implications for therapeutic intervention in chronic inflammatory diseases
Recent Advances in Stem Cell Research
Design and Synthesis of Functionalized Mn (III) Dipyrromethene Complexes as Peroxynitrite Decomposition Catalysts
Thrive with diabetes
The in vitro and in vivo anti-oxidative and anti-diabetic effects of some African medicinal plants and the identification of the bioactive compounds.
Health seeking and health related behaviour for type 2 diabetes mellitus among adults in an urban community in Tanzania
Manipulating Protein Stability with Small Molecules: Applications in studying biological systems and accessing new drug targets
Message from Chief Guest
Role of Endoplasmic Reticulum Stress Response Signaling in T Cells: A Dissertation
Physiological Consequences of Compartmentalized Glycerolipid Synthesis
Cost-effectiveness of disease interventions in India
Putting ‘sugar diabetes’ on the table: Evaluating “The Sugar Plays” as entertainment-education in Appalachia
Community Based Interactive Approach for Type 2 Diabetic Patients at Addaraja Health Center, Wad Medani, Sudan
Emotional Vampires and Your Hormones: An Holistic Physician’s View on How Stress Affects Your Well-Being and What You Can Do About It
The Role and Regulation of Sox9 in the Human Hair Follicle and Basal Cell Carcinoma
A bittersweet existence: the lived experiences of four young women with diabetes mellitus
Acid-base balance and oxidative metabolism in calcified tissues
Investigation Into the Role of ER Stress in the Pathology of Metaphyseal Chondrodysplasia Type Schmid
WNT SIGNALLING IN NORMAL DEVELOPMENT AND CANCER PROGRESSION
… and insulin resistance: New targets encourage new thinking: Galectin‐3 and LTB4 are pro‐inflammatory molecules that can be targeted to restore insulin sensitivity
Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore insulin sensitivity in the Diet-Induced Obesity in Vivo Mouse Model
Interleukin-4 restores insulin sensitivity in lipid-induced insulin-resistant adipocytes
Two nights of recovery sleep restores the dynamic lipemic response, but not the reduction of insulin sensitivity, induced by five nights of sleep restriction
Cutting calories and TXNIP from the skeletal muscle to restore insulin sensitivity
Gal3 links inflammation and insulin resistance
Avocatin B Protects Against Lipotoxicity and Improves insulin sensitivity in Diet‐Induced Obesity
A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
Chaperone-based therapeutic target innovation: Heat shock protein 70 (HSP70) for Type 2 diabetes mellitus
Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance
Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2
Cardiovascular and Metabolic Consequences of Sleep and/or Circadian Disruption: Two nights of recovery sleep restores the dynamic lipemic response, but …
Mitochondria and endoplasmic reticulum: Targets for a better insulin sensitivity in skeletal muscle?
Developmental programming: impact of gestational steroid and metabolic milieus on mediators of insulin sensitivity in prenatal testosterone–treated female sheep
Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high-fat feeding regardless of insulin-sensitizing treatment
Adipocyte JAK2 regulates hepatic insulin sensitivity independently of body composition, liver lipid content, and hepatic insulin signaling
Tumour necrosis factor α induces neuroinflammation and insulin resistance in immortalised hypothalamic neurones through independent pathways
Impact of sleep deprivation and high-fat feeding on insulin sensitivity and beta cell function in dogs
Functional abolition of carotid body activity restores insulin action and glucose homeostasis in rats: key roles for visceral adipose tissue and the liver
Targeting insulin resistance with selected antidiabetic agents prevents menopausal associated central obesity, dysglycemia, and cardiometabolic risk
Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice
Obesity-associated alterations in glucose metabolism are reversed by chronic bilateral stimulation of the abdominal vagus nerve
The manifold role of the mitochondria in skeletal muscle insulin resistance
S-Nitrosoglutathione Reverts Dietary Sucrose-Induced insulin Resistance
High frequency shift in Carotid Sinus Nerve and Sympathetic Nerve activity in Type 2 Diabetic Rat Model*
Nutrient restriction increases circulating and hepatic ceramide in dairy cows displaying impaired insulin tolerance
Obesity in menopause–our negligence or an unfortunate inevitability?
Effect of aging on current flow due to transcranial direct current stimulation
TXNIP in metabolic regulation: physiological role and therapeutic outlook
Increased insulin sensitivity by High-Altitude Hypoxia in Mice with High-Fat Diet-Induced Obesity Is Associated with Activated AMPK Signaling and Subsequently …
Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8
Effects of a ruthenium schiff base complex on glucose homeostasis in diet-induced pre-diabetic rats
The transcription factor Prep1 controls hepatic insulin sensitivity and gluconeogenesis by targeting nuclear localization of FOXO1
Protocatechuic acid exhibits hepatoprotective, vasculoprotective, antioxidant and insulin-like effects in dexamethasone-induced insulin-resistant rats
Interleukin-4 Restores insulin sensitivity in insulin-Resistant Osteoblasts by Increasing the Expression of insulin Receptor Substrate 1
Plant Bioactives and the Intestinal Barrier: Redox Signaling and Implications for insulin Resistance
Regulation of insulin sensitivity by Skeletal Muscle Specific Modulation Of p21‐Activated Kinase 1 (PAK1)
Samidorphan mitigates olanzapine-induced weight gain and metabolic dysfunction in rats and non-human primates
MicroRNA miR-222 mediates pioglitazone beneficial effects on skeletal muscle of diet-induced obese mice
Oridonin prevents insulin resistance–mediated cognitive disorder through PTEN/Akt pathway and autophagy in minimal hepatic encephalopathy
Endoplasmic reticulum stress causes insulin resistance by inhibiting delivery of newly synthesized insulin receptors to the cell surface
A hypothesis for insulin resistance in primary human adipocytes involving MRTF-A and suppression of PPARγ
Cefdinir microsphere modulated microflora and liver immunological response to diet induced diabetes in mice
Effect of single anastomosis duodenal-ileal bypass with sleeve gastrectomy on glucose tolerance test: comparison with other bariatric procedures
Exercise and polycystic ovary syndrome
Hematopoietic Cell–Expressed Endothelial Nitric Oxide Protects the Liver From insulin Resistance
insulin resistance and Parkinson’s disease: a new target for disease modification?
Arginase inhibition prevents the development of hypertension and improves insulin resistance in obese rats
Protective role of osteocalcin in diabetes pathogenesis
Serum Level of Galectin-3 and Its Relation to insulin Resistance in Patients with Androgenetic Alopecia
Effect of thiazolidinediones on adipocytokines and lipid profile in insulin resistant sprague dawley rats
Transcranial direct current stimulation (tDCS) improves cognitive-motor performance in older adults with cerebral microvascular disease
IL-17A contributes to propagation of inflammation but does not impair adipogenesis and/or insulin response, in adipose tissue of obese individuals
Mitochondrial (Dys) function and insulin resistance: from pathophysiological molecular mechanisms to the impact of diet
THE EFFECTS OF SLEEP RESTRICTION AND SUBSEQUENT SLEEP RECOVERY ON GLYCEMIC AND LIPEMIC METABOLISM.
Anthocyanin Improves Glucose Homeostasis in Obese Mice via Regulation of Intestinal Microbiota and Barrier Function
Could vagus nerve stimulation have a role in the treatment of diabetes?
Mitochondria Dysfunction in Aging and Metabolic Diseases: Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with …
Impact of exercise on glucose homeostasis in different mouse models for impaired insulin sensitivity
The metabolic stress response to burn trauma: current understanding and therapies
2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes
insulin Resistance and T1D: The Effect of Exercise on Skeletal Muscle Lipid Metabolism
SGLT inhibitors for type 1 diabetes: an obvious choice or too good to be true?
The Effects of Western-diet, Palmitate, and TNFα on Hypothalamic Circadian Rhythms, NPY Expression, Neuroinflammation, and Cellular insulin sensitivity
The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight …
9-Therapeutic Targeting of Skeletal Muscle Nix in Early-Onset insulin Resistance
Regulation of skeletal muscle insulin sensitivity by PAK1
Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator–activated receptor γ (PPARγ) …
The in Silico Study of Nutmeg Seeds (Myristica fragrans Houtt) as Peroxisome Proliferator Activated Receptor Gamma Activator Using 3D-QSAR …
Modulation of visfatin levels by thiazolidinediones in insulin resistant sprague dawley rats
Synergistic Effect of Two Major Components of Malva verticillata in the Recovery of Alloxan-Damaged Pancreatic Islet Cells in Zebrafish
TNF-α as an Adipokine
Anti-diabetic effects of excipients: possibility of formulation of an anti-diabetic dosage form using pharmaceutical excipients or their constituents, or food …
12-Examining the Role of the HNF-1a G319S Variant in Liver Function and Early-Onset Type 2 Diabetes
11-Investigating the Roles of Transcription Factor EB (TFEB) in β-Cell Function and Survival Under Stress
Treatment of insulin resistance: straight from the gut
Revisiting Caloric Restriction as Therapeutic Strategy for Metabolic Syndrome, T2DM and Obesity
Reducing the burden of obesity-associated cancers with anti-inflammatory long-chain omega-3 polyunsaturated fatty acids
Ad libitum weekend recovery sleep fails to prevent metabolic dysregulation during a repeating pattern of insufficient sleep and weekend recovery sleep
Mechanisms of macrophage polarization in insulin signaling and insulin sensitivity
Why We Age: From Healthy Aging
PPARγ in complex with an antagonist and inverse agonist: a tumble and trap mechanism of the activation helix
IRS posttranslational modifications in regulating insulin signaling
Adiponectin and aldosterone in left ventricular hypertrophy: an intriguing interplay
Overview of ketone-based metabolism
UNRAVELING THE LINK BETWEEN CAROTID BODY, insulin AND DOPAMINE.
Role of Omega-3 Fatty Acids in Metabolic Syndrome
Correction of metabolic acidosis improves insulin resistance in chronic kidney disease
Antidiabetic effect of casein glycomacropeptide hydrolysates on high-fat diet and STZ-induced diabetic mice via regulating insulin signaling in skeletal muscle and …
Developmental programming: insulin sensitizer prevents the GnRH-stimulated LH hypersecretion in a sheep model of PCOS
Poly (I: C) alleviates obesity related pro-inflammatory status and promotes glucose homeostasis
The Effects of Estrogen, Grape Pomace, and Resveratrol Supplementation on Glucose Tolerance and insulin Signaling in Ovariectomized Rats.
Casein glycomacropeptide hydrolysates ameliorate hepatic insulin resistance of C57BL/6J mice challenged with high-fat diet
Knockdown of PTRF ameliorates adipocyte differentiation and functionality of human mesenchymal stem cells
AMPK activation by metformin suppresses abnormal extracellular matrix remodeling in adipose tissue and ameliorates insulin resistance in obesity
Markedly improved glycemic control in poorly controlled type 2 diabetes following direct acting antiviral treatment of genotype 1 hepatitis C
Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance
Characterizing the Mechanisms of insulin Resistance in Dairy Cattle
Preventive effect of oleate on palmitate-induced insulin resistance in skeletal muscle and its mechanism of action
Vitamin D deficiency causes insulin resistance by provoking oxidative stress in hepatocytes
CCL5/RANTES contributes to hypothalamic insulin signaling for systemic insulin responsiveness through CCR5
Rosiglitazone improves insulin resistance mediated by 10, 12 conjugated linoleic acid in a male mouse model of metabolic syndrome
insulin resistance elicited in postpubertal primate offspring deprived of estrogen in utero
Houttuynia cordata facilitates metformin on ameliorating insulin resistance associated with gut microbiota alteration in OLETF rats
Class effect for SGLT-2 inhibitors: a tale of 9 drugs
Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells
Vitamin D deficiency enhances insulin resistance by promoting inflammation in type 2 diabetes
Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes
Cyanidin-3-O-glucoside restores insulin signaling and reduces inflammation in hypertrophic adipocytes
Role of probiotics in diabetes: a review of their rationale and efficacy
Uncovering the Complex Metabolic Role of Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT)
Antidiabetic and Cardioprotective Effects of Pharmacological Inhibition of GRK2 in db/db Mice
Metabolomic response of skeletal muscle to aerobic exercise training in insulin resistant type 1 diabetic rats
TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl) purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway
Long-term hypercaloric diet consumption exacerbates age-induced metabolic dysfunction: Beneficial effects of CSN denervation
The effect of electric field, magnetic field, and infrared ray combination to reduce HOMA-IR index and GLUT 4 in diabetic model of Mus musculus
Thyroid function and risk of type 2 diabetes: a population-based prospective cohort study
Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women
Polyphenol‐rich virgin olive oil reduces insulin resistance and liver inflammation and improves mitochondrial dysfunction in high‐fat diet fed rats
Targeting inflammation and downstream protein metabolism in sarcopenia: a brief up-dated description of concurrent exercise and leucine-based multimodal …
Oleuropein ameliorates palmitate-induced insulin resistance by increasing Glut4 translocation through activation of AMPK
Pharmacological targeting of the unfolded protein response for disease intervention
Effect of ionic liquid components on the coil dimensions of PEO
The unfolded protein response and hepatic lipid metabolism in non alcoholic fatty liver disease
Purple sweet potato color improves hippocampal insulin resistance via down-regulating SOCS3 and galectin-3 in high-fat diet mice
Heat therapy improves glucose tolerance and adipose tissue insulin signaling in polycystic ovary syndrome
Redox-Responsive Dipeptide Nanostructures toward Targeted Cancer Therapy
Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition
Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain
Role of pro-and anti-inflammatory phenomena in the physiopathology of type 2 diabetes and obesity
C-Phycocyanin inhibits hepatic gluconeogenesis and increases glycogen synthesis via activating Akt and AMPK in insulin resistance hepatocytes
Mesoporous TiO2 Support Materials for Ru-Based CO2 Methanation Catalysts
Developmental programming of PCOS traits: insights from the sheep
The Potential Anti-Diabetic Effects of Some Plant Species
Pharmacological Targeting of IRE1α Ameliorates insulin Resistance Through Preservation of the insulin Receptor Signaling Pathway
Protocatechuic acid improves hepatic insulin resistance and restores vascular oxidative status in type-2 diabetic rats
Starvation, carbohydrate loading, and outcome after major surgery
Current trends in small molecule discovery targeting key cellular signaling events towards the combined management of diabetes and obesity
Metformin in the treatment of adults with type 2 diabetes mellitus
Ab Initio Study of CO2 Capture Mechanisms in Aqueous 2-Amino-2-methyl-1-propanol: Electronic and Steric Effects of Methyl Substituents on the Stability of …
Coordinated regulation of miR-27 by insulin/CREB/Hippo contributes to insulin resistance
Adiponectin is required for pioglitazone-induced improvements in hepatic steatosis in mice fed a high-fat diet
Exercise and insulin resistance in PCOS: muscle insulin signalling and fibrosis
The role of dietary fat in obesity-induced insulin resistance
Disturbances in insulin–Glucose Metabolism in Patients With Advanced Renal Disease With and Without Diabetes
Manipulation of the growth hormone-insulin-like growth factor (GH-IGF) axis: A treatment strategy to reverse the effects of early life developmental programming
The Effect of Bean Juice for Reduction Blood Glucose Levels in Psychological Stress
Osteocalcin prevents insulin resistance, hepatic inflammation, and activates autophagy associated with high-fat diet–induced fatty liver hemorrhagic syndrome …
Anti-inflammatory effect of piperine ameliorates insulin resistance in monosodium glutamate–treated obese mice
Niclosamide as an anti-obesity drug: an experimental study
Th17 and Treg lymphocytes in obesity and Type 2 diabetic patients
Bortezomib attenuates palmitic acid-induced ER stress, inflammation and insulin resistance in myotubes via AMPK dependent mechanism
Silibinin attenuates adipose tissue inflammation and reverses obesity and its complications in diet-induced obesity model in mice
Effect of metformin monotherapy on serum lipid profile in statin-naïve individuals with newly diagnosed type 2 diabetes mellitus: a cohort study
insulin signalling in hypothalamic neurones
PPARG post-translational modifications regulate bone formation and bone resorption
Regulation of hepatic glucose metabolism in health and disease
Mechanisms of insulin action and insulin resistance
Relationship between metabolic disorders and breast cancer incidence and outcomes. Is there a preventive and therapeutic role for berberine?
Neratinib protects pancreatic beta cells in diabetes
IP6K1 reduces mesenchymal stem/stromal cell fitness and potentiates high fat diet‐induced skeletal involution
Nigella sativa L. oil ameliorates insulin resistance caused by dexamethasone treatment in male Wistar rats
Hyperglycemia-associated alterations in cellular signaling and dysregulated mitochondrial bioenergetics in human metabolic disorders
Therapeutic potential of the dual peroxisome proliferator activated receptor (PPAR) α/γ agonist aleglitazar in attenuating TNF-α-mediated inflammation and insulin …
Quantitative in vivo proteomics of metformin response in liver reveals AMPK-dependent and-independent signaling networks
Amlexanox reversed non-alcoholic fatty liver disease through IKKε inhibition of hepatic stellate cell
Adipocytes properties and crosstalk with immune system in obesity‐related inflammation
Cinnamon extract combined with high-intensity endurance training alleviates metabolic syndrome via non-canonical WNT signaling
Metformin reverses established lung fibrosis in a bleomycin model
Towards resolving the enigma of the dichotomy of resveratrol: cis-and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation
Elevated Carbohydrate Response Element-Binding Protein Beta (ChREBPβ) and Thioredoxin Interacting Protein (TXNIP) Levels in Human Adipocytes Differentiated …
insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine
Mesenchymal stem cell therapy in type 2 diabetes mellitus
NHX-5, an endosomal Na+/H+ exchanger, is associated with metformin action
Effects of zingiber officinale extract supplementation on metabolic and genotoxic parameters in diet-induced obesity in mice
Effect of long-term growth hormone replacement on glucose metabolism in adults with growth hormone deficiency: a systematic review and meta-analysis
The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)–mediated glucose uptake into skeletal muscle cells
Role of gut microbiota in type 2 diabetes pathophysiology
Rac1 and AMPK account for the majority of muscle glucose uptake stimulated by ex vivo contraction but not in vivo exercise
Lower Blood Sugar Prevents Diabetes
Role of hyperglycaemia in the relationship between serum osteocalcin levels and relative skeletal muscle index
Role of the blood-brain barrier in central nervous system insulin resistance
Promising inhibitory effects of anthraquinones, naphthopyrone, and naphthalene glycosides, from Cassia obtusifolia on α-glucosidase and human protein tyrosine …
Additional effect of metformin and celecoxib against lipid dysregulation and adipose tissue inflammation in high-fat fed rats with insulin resistance and fatty liver
Thyroid hormone analogs for the treatment of dyslipidemia: past, present, and future
Alkaloids potential health Benefits and toxicity
Innate lymphoid cells as novel regulators of obesity and its‐associated metabolic dysfunction
Protein tyrosine phosphatase 1B (PTP1B): a potential target for Alzheimer’s therapy?
Xenobiotic mediated diabetogenesis: Developmental exposure to dichlorvos or atrazine leads to type 1 or type 2 diabetes in Drosophila
Closed-loop control systems–The quest for precision therapies for diabetes
Potential Protective Effects of Neonatal Supplementation with Oleanolic Acid on Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)-Ligand Dependent …
Bone-derived factors: a new gateway to regulate glycemia
Angiotensin receptor subtypes regulate adipose tissue renewal and remodelling
Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials
Evaluation of DEFB1 polymorphisms in individuals with chronic periodontitis and diabetes mellitus type 2 in a population of northeastern Brazil
Possible effects of dietary anthocyanins on diabetes and insulin resistance
New Era of Perio Systemic Interrelationship
Anti-adiposity impact of phosphodiesterase-5 inhibitor, Sildenafil is possibly through browning of white adipose tissue and FGF21 in obese rats
Developmental programming: gestational testosterone excess disrupts LH secretion in the female sheep fetus
Glucose-lowering Strategies in Diabetes: Pharmacological Development of New Anti-diabetic Drugs
Dietary 23-hydroxy ursolic acid protects against diet-induced weight gain and hyperglycemia by protecting monocytes and macrophages against nutrient stress …
Influence on hydrate dissociation for methane hydrates formed in the presence of PolyVinylCaprolactam versus PolyVinylCaprolactam+ Butyl Glycol Ether
Circulating adiponectin levels in type 2 diabetes mellitus patients with or without non-alcoholic fatty liver disease: Results of a small, open-label, randomized …
Acute effects of active breaks during prolonged sitting on subcutaneous adipose tissue gene expression: an ancillary analysis of a randomised controlled trial
Thyroid hormone analogues: An update
Investigation of plasma asprosin and saliva levels in newly diagnosed type 2 diabetes mellitus patients treated with metformin
Increased mitochondrial calcium uniporter in adipocytes underlies mitochondrial alterations associated with insulin resistance
The Effects of Solvent Polarity on Hypoglycemic and Hypolipidemic Activities of Vaccinium Arctostaphylos L. Unripe Fruits
Inflammatory features of obesity and smoke exposure and the immunologic effects of exercise
The apelin/APJ system as a therapeutic target in metabolic diseases
For Management of Obesity and Diabetes: Is Timing the Answer?
Nonalcoholic fatty liver disease as a nexus of metabolic and hepatic diseases
Biohydrogenation of linoleic acid by lactic acid bacteria for the production of functional cultured dairy products: A review
Resistin in metabolism, inflammation, and disease
Tailoring treatment for PCOS phenotypes
Growth hormone and insulin signaling in acromegaly: impact of surgery versus somatostatin analog treatment
DUSP5 Regulation of Inflammation and insulin Signaling
Bariatric and metabolic therapies targeting the small intestine
Essential roles for the non-canonical IκB kinases in linking inflammation to cancer, obesity, and diabetes
The effect of type 2 diabetes diagnosis in the elderly
Sexual function, obesity, and weight loss in men and women
The chronic effects of dietary (poly) phenols on mitochondrial dysfunction and glucose uptake in cellular models of the liver and skeletal muscle.
Does improved periodontal health affect metabolic and inflammatory markers in patients with diabetes mellitus? A comparative study
Nitric oxide exerts basal and insulin-dependent anorexigenic actions in POMC hypothalamic neurons
Resveratrol and quercetin administration improves antioxidant DEFENSES and reduces fatty liver in metabolic syndrome rats
Identification of putative biomarkers for type 2 diabetes using metabolomics in the Korea Association REsource (KARE) cohort
Downregulation of miR-181a alleviates renal fibrosis in diabetic nephropathy mice
Protective Effects and Mechanisms of Action of methyl-GBB in the Preclinical Models of Diabetes and Its Complications. Summary of the Doctoral Thesis
VEGF-B antibody and interleukin-22 fusion protein ameliorates diabetic nephropathy through inhibiting lipid accumulation and inflammatory responses
Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome
Comorbidities and nonalcoholic fatty liver disease: the chicken, the egg, or both?
Deletion of TXNIP mitigates high-fat diet-impaired angiogenesis and prevents inflammation in a mouse model of critical limb ischemia
Thyroid hormone mimetics: the past, current status and future challenges
The effects of a [3+ 1] oxo-free rhenium (V) compound with uracil-derived ligands on selected parameters of glucose homeostasis in diet-induced pre-diabetic …
Autoimmunity, Non-Classic Adrenal Hyperplasia, insulin Resistance, and Vitamin D
Effects of ursodeoxycholic acid and insulin on palmitate-induced ROS production and down-regulation of PI3K/Akt signaling activity
Changes in Mitochondrial Dynamics and iNOS in the Dorsal Vagal Complex of the Brain affects insulin Sensing, Feeding Behaviours and Body Weight Gain in Rats
Intestinal microbiota and the immune system in metabolic diseases
AMPK: guardian of metabolism and mitochondrial homeostasis
insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine
Δ9-Tetrahydrocannabivarin (THCV): a commentary on potential therapeutic benefit for the management of obesity and diabetes
Five stages of progressive β-cell dysfunction in the laboratory Nile rat model of type 2 diabetes
insulin resistance disrupts epithelial repair and niche-progenitor Fgf signaling during chronic liver injury
Targeting glucosylceramide synthesis in the treatment of rare and common renal disease
The immune system and microbiome in pregnancy
Ultra‐Performance Liquid Chromatography‐Mass Spectrometry Analysis of Free and Esterified Oxygenated Derivatives from Docosahexaenoic Acid in Rat Brain
Role of c-Jun N-terminal kinase (JNK) in obesity and type 2 diabetes
Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle
Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions
Novel Aspects of Adipocyte Biology: Increased mitochondrial calcium uniporter in adipocytes underlies mitochondrial alterations associated with insulin …
The role of the autonomic nervous system in the pathophysiology of obesity
Insights into the Functional Roles of Exercise in Type 2 Diabetes Using In Vitro Models
Wingless-type MMTV integration site family member 5a: a novel biomarker regulated in type 2 diabetes mellitus and diabetic kidney disease
Investigating the Wnt/β-catenin Pathway in Conventional Dendritic cells in Obesity-Induced Tissue Inflammation and insulin Resistance
A low fat diet ameliorates pathology but retains beneficial effects associated with CPT1b knockout in skeletal muscle
Antihyperglycemic and antioxidant effect of the total flavones of Potentilla kleiniana Wight et Arn. in streptozotocin induced diabetic rats.
The effects of high dietary doses of chromium (III) complex with propionic acid on nutritional and selected blood indices in healthy female rats
Type 2 diabetes treatment in the patient with obesity
Lower Leg Fat Depots Are Associated with Albuminuria Independently of Obesity, insulin Resistance, and Metabolic Syndrome (Korea National Health and …
Influence of resveratrol on endoplasmic reticulum stress and expression of adipokines in adipose tissues/adipocytes induced by high-calorie diet or palmitic acid
The Effect of Pituitary Gland Disorders on Glucose Metabolism: From Pathophysiology to Management
Autophagy as an emerging target in cardiorenal metabolic disease: From pathophysiology to management
Therapeutic molecules against type 2 diabetes: What we have and what are we expecting?
Angiotensin II Mediated Regulation of Signal Transduction in Metabolic Syndrome and Cancer
Innate immune control of adipose tissue homeostasis
A novel metformin derivative showed improvement of lipid metabolism in obese rats with type 2 diabetes
Correlation between PAI-1, leptin and ferritin with HOMA in HIV/AIDS patients
Research progress on the role of gal-3 in cardio/cerebrovascular diseases
36 Care of Geriatric Patients
From diabetes care to diabetes cure—the integration of systems biology, eHealth, and behavioral change
MicroRNA, proteins, and metabolites as novel biomarkers for prediabetes, diabetes, and related complications
Senescence alters PPARγ (Peroxisome Proliferator–Activated Receptor Gamma)-dependent fatty acid handling in human adipose tissue microvascular endothelial …
Lactobacillus pentosus S-PT84 prevents LPS-induced low-grade chronic inflammation in a C57BL/6J mouse model
Adipose tissue macrophage heterogeneity and the role of Tim4⁺ macrophages in lipid homeostasis
Promises of nanotherapeutics in obesity
Prevalence of Thyroid Dysfunction in a Chinese Population with Different Glucose Intolerance Status: A Community-Based Cross-Sectional Study
Investigation of C-glycosylated apigenin and luteolin derivatives’ effects on protein tyrosine phosphatase 1B inhibition with molecular and cellular approaches
Biochemical and Haematological Effects of the Leaf Extract of Newbouldia laevis in Alloxan-Induced Diabetic Rats
Thermal Injury
Dual Peroxisome Proliferator-activated Receptor Agonists
The Carotid Body a Common Denominator for Cardiovascular and Metabolic Dysfunction?
The right place for Sulphonylureas today: Part of ‘Review the Series: Implications of recent CVOTs in Type 2 diabetes mellitus’
The bioenergetics of inflammation: insights into obesity and type 2 diabetes
Physical exercise as an epigenetic modulator of brain plasticity and cognition
Fibronectin type III domain-containing 5 in cardiovascular and metabolic diseases: a promising biomarker and therapeutic target
The EP3 Receptor/G z Signaling Axis as a Therapeutic Target for Diabetes and Cardiovascular Disease
Thyroid screening in prediabetes: Does it have any role?
Pharmacological Inhibition of Galectin-3 Ameliorates Diabetes-Associated Cognitive Impairment, Oxidative Stress and Neuroinflammation in vivo and in vitro
Care of Geriatric Patients
The Microvascular Control of insulin Action and insulin Resistance in Skeletal Muscle
Adipokines, inflammation, and insulin resistance in obesity
Hepatoprotective Effects of a Ruthenium (II) Schiff Base Complex in Rats with Diet-Induced Prediabetes
Dual-specificity phosphatases regulate mitogen-activated protein kinase signaling in adipocytes in response to inflammatory stress
Trigonella foenum-graceum (fenugreek) for Managemen of Diabetes
AICAR Influences AS160 Phosphorylation and Autophagy Induction via the GSK3β-TIP60-ULK1 Pathway
Pharmacological aspects of the safety of gliflozins
Epidemiology, risk factors across the spectrum of age-related metabolic diseases
The emerging therapeutic potential of nitro fatty acids and other Michael acceptor-containing drugs for the treatment of inflammation and cancer
Genetic variants influence the response of body composition and insulin resistance to dietary monounsaturated fatty acids consumption
Sobetirome: the past, present and questions about the future
Unwinding Complexities of Diabetic Alzheimer by Potent Novel Molecules
Prevalence of mild cognitive impairment in type 2 diabetes mellitus is associated with serum galectin‐3 level
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay
Impact of Drugs on Diabetes Risk and Glycemic Control
Connecting Pathway Errors in the insulin Signaling Cascade: The Molecular Link to Inflammation, Obesity, Cancer, and Alzheimer’s Disease
Could Galectin 3 Be a Good Prognostic Factor in Endometrial Cancer?
Thyroid hormones, thyromimetics and their metabolites in the treatment of liver disease
Roles of galectin-3 in metabolic disorders and tumor cell metabolism
Metformin inhibits both oleic acid-induced and CB1R receptor agonist-induced lipid accumulation in Hep3B cells: The preliminary report
Serum ferritin correlates with liver fat in male adolescents with obesity
Metabolic Targets in Nonalcoholic Steatohepatitis: Treating the Disease at the Metabolic Root
Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat
Combinations of regenerative medicine and Lab-on-a-chip systems: New hope to restoring the proper function of pancreatic islets in diabetes
Organotypic vasculature: from descriptive heterogeneity to functional pathophysiology
The Effects of the N-hexane Fractions of Heinsia crinita Leaf Extract on Electrolyte Balance and Some Haematological Parameters of Alloxan-induced Diabetic Albino …
The effect of phase I therapy on the clinical parameters, VSC levels, and RBS levels in chronic periodontitis patients with diagnosed diabetes
Liver function as an engineering system
Abietane-type diterpenoids inhibit protein tyrosine phosphatases by stabilizing an inactive enzyme conformation
A story of metformin-butyrate synergism to control various pathological conditions as a consequence of gut microbiome modification: genesis of a wonder drug?
Androgen effect on body weight and behaviour of male and female rats: novel insight on the clinical value
Interleukin-4 retards liver fibrosis in Balb/C mice model of carbon tetra-chloride (CCl4)-associated with decreased CD80 and interleukin-12 expressions
Associatio n of Diabetes mellitus and Thyroid disorders: A metabolic prospective
The Secrets You Should Know About Sexual Medicine; Part One; Obesity and Sexual Dysfunction
iNOS as a metabolic enzyme under stress conditions
Selective serotonin reuptake inhibitors affect structure, function and metabolism of skeletal muscle: a systematic review
Anti-hyperglycemic effect of aqueous extract of Juglans regia L. leaf (walnut leaf) on type 2 diabetic patients: A randomized controlled trial
Polycystic Ovarian Syndrome (PCOS) and Nutritional Supplementation©
Effect of fenugreek consumption with metformin treatment in improving plaque index in diabetic patients
Effect of JAK-STAT pathway in regulation of fatty liver hemorrhagic syndrome in chickens
24 h pre-incubation of EA. hy926 cells with angiotensin II regulates insulin-dependent activation of eNOS in a concentration-dependent manner
The potential of artemisinins as anti-obesity agents via modulating the immune system
Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol and 8‐prenylnaringenin: Unveiling the angiogenic paradox and metabolism interplay
Pattern and correlates of hypomagnesemia among subset of diabetes mellitus
Obesity and cancer metabolism: a perspective on interacting tumor–intrinsic and extrinsic factors
The molecular basis of hepatic de novo lipogenesis in insulin resistance
Interleukin-4 Retards Liver Fibrosis in Balb/C Mice Model of Carbon Tetra-Chloride (CCl
Deep multi-OMICs and multi-tissue characterization in a pre-and postprandial state in human volunteers: the GEMM family study research design
Hematoprotective and nephroprotective properties of ethanolic extract of Anthemis odontostephana Boiss in Streptozotocin-induced diabetic mice
ADIPOSE TISSUE-TARGETED STEM CELL TRANSPLANTATION FOR insulin RESISTANCE-RELATED CNS DEFICITS
Inhibition of Hypothalamic Inhibitor κB Kinase β/Nuclear Transcription Factor κB Pathway Attenuates Metabolism and Cardiac Dysfunction in Type 2 Diabetic Rats
The SERCA3 Pathway is Correlated to Optimal insulin Secretion in Pancreatic Cell Lines Derived From Type-2 Diabetic Patients
The SERCA3 Pathway is Correlated to Optimal insulin Secretion in Pancreatic Cell Lines Derived From Type-2 Diabetic Patients
insulin: its role in growth of fetus and child
Metabolic Diseases and Aging 17
Double lipoxygenation of polyunsaturated fatty acids of nutritional interest
Evaluation of micronutrient (zinc, magnesium, and copper) levels in serum and glycemic status after nonsurgical periodontal therapy in type 2 diabetic patients …
Investigating the Redox Properties of Two-Dimensional MoS2 Using Photoluminescence Spectroelectrochemistry and Scanning Electrochemical Cell Microscopy
Development of Microfluidic Platform to Study insulin Resistance
2, 4 dinitrophenol as medicine
The role of Peroxisome Proliferator-Activated Receptors (PPAR) in immune responses
PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency
Why do I treat my patients with mild hepatitis C?
Costus afer modulates the activities of glycolytic and gluconeogenic enzymes in streptozotocin induced diabetic rats
Periodontics and Oral-Systeric Relationships: Diabetes
Metabolic Diseases and Aging
Myocardial metabolism in heart failure: purinergic signalling and other metabolic concepts
Backbone resonance assignments of the catalytic and regulatory domains of Ca 2+/calmodulin-dependent protein kinase 1D
Inflammatory signaling and brown fat activity
Combined metformin and resveratrol confers protection against UVC-induced DNA damage in A549 lung cancer cells via modulation of cell cycle checkpoints …
Syringic acid improves oxidative stress and mitochondrial biogenesis in the liver of streptozotocin-induced diabetic rats
pre-existing diabetes and PTDM in kidney transplant recipients: how to handle immunosuppression
THR-ß agonism improves disease activity and metabolism independent of body weight in a mouse model of non-alcoholic steatohepatitis and fibrosis
Adipose stem cells in obesity: challenges and opportunities
Performance enhancement drugs and sports supplements: A review of the evidence
Plaque imaging to refine indications for emerging lipid-lowering drugs
The START-domain proteins in intracellular lipid transport and beyond
Rosiglitazone ameliorates bile duct ligation-induced liver fibrosis by down-regulating NF-κB-TNF-α signaling pathway in a PPARγ-dependent manner
Obesity: current treatment and future horizons
Berberine ameliorates obesity-induced chronic inflammation through suppression of ER stress and promotion of macrophage M2 polarization at least partly via …
D-chiro inositol phosphoglycans in preeclampsia: where are we, where are we going?
Resistance training modulates the humoral inflammatory (but not the DNA methylation) profile of diabetic older adults using metformin
Hematoprotective and nephroprotective effects of Achillea millefolium aqueous extract in diabetic mice
Potential impact of Paracentrotus lividus extract on diabetic rat models induced by high fat diet/streptozotocin
Endothelial progenitor cells as pathogenetic and diagnostic factors, and potential targets for GLP-1 in combination with metabolic syndrome and chronic obstructive …
Red raspberries and their bioactive polyphenols: cardiometabolic and neuronal health links
Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges
Nutraceutical prospective: The synergetic mechanism of action of inositols and resveratrol on metabolic syndrome
Diabetes & Obesity—Diabesity: A Genetic Curse or an Eating Hazard—How to Unmake the Mistake
Interrelationship of canonical and non-canonical Wnt signalling pathways in chronic metabolic diseases
Sulindac decreases basal-like mammary tumor burden and pro-inflammatory mediators in obese mice
A pharmacokinetic study of GC-1 delivery using a nanochannel membrane device
The effect of periodontal and prosthodontic therapy on glycemic control in patients with diabetes
Hydrogen sulfide signaling in mitochondria and disease
Synergistic Effects of Metformin and Cocoa Flavanol on Inflammatory and Oxidant Markers Induced by Carrageenan: Pathophysiological Approach
Metformin Revisited
Myocardial glucotoxicity: Mechanisms and potential therapeutic targets
368 SECTION 2 Syndromes by Body System: The Gastrointestinal System
Metformin ameliorates the phenotype transition of peritoneal mesothelial cells and peritoneal fibrosis via a modulation of oxidative stress
Inhibition of the Renin–Angiotensin System: How Far Have We Come?
NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression
Mitochondrial Dynamics in the Brain Are Associated With Feeding, Glucose Homeostasis, and Whole-Body Metabolism
Diabetes and Periodontal Disease: A Two-Way Relationship
Identification of heme oxygenase-1 as a novel predictor of hematopoietic stem cell transplantation outcomes in acute leukemia
Olive Oil in Metabolic Syndrome
Identification of novel molecular mechan therapeutic strategy in cardiovascular disea
Evaluation of the therapeutic properties of a Ruthenium (ll) uracil-derived diimine complex on selected complications associated with diet-induced pre-diabetes.
Metabolic Bioactivity of Athrixia phylicoides
Jay Ian Lakkis and Matthew R. Weir
The mitochondrial Ca2+ uptake and the fine-tuning of aerobic metabolism
FACULTEIT GENEESKUNDE EN LEVENSWETENSCHAPPEN
Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production
Inflammatory and oxidative stress markers in skeletal muscle of obese subjects
Research methodology for in vivo measurements of resting energy expenditure, daily body temperature, metabolic heat and non-viral tissue-specific gene therapy in …
Microdose Lithium Protects against Pancreatic Islet Destruction and Renal Impairment in Streptozotocin-Elicited Diabetes
Antihyperglycemic Effect of an Important Phytocompound-Phloretin on Streptozotocin Induced Diabetes: An Experimental Study
Estrogen signaling and UCP1: exploring mechanisms to improve metabolic health
Antioxidant potential of biflavonoid attenuates hyperglycemia by modulating the carbohydrate metabolic enzymes in high fat diet/streptozotocin induced diabetic rats
Impact of Chronic Periodontitis on Systemic Conditions: A Review
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in …
Pharma-nutritional properties of olive oil phenols. Transfer of new findings to human nutrition
Potential of Rasāhāra and Yoga in Treatment of Pre Diabetes-A Controlled Trial
Post Kidney Transplant: Obesity
Fundamental role of Warburg effect in various pathophysiological processes
Lipid (per) oxidation in mitochondria: an emerging target in the ageing process?
A metabolic inhibitory cocktail for grave cancers: metformin, pioglitazone and lithium combination in treatment of pancreatic cancer and glioblastoma multiforme
Chronic Passive Heat Exposure and Cardiometabolic Health in Obese Women with Polycystic Ovary Syndrome
Dr. Cimino’s Weight Loss Solution: The No Calorie Counting, No Exercise, Rapid Weight Loss Plan
Nonalcoholic fatty liver disease and hypercholesterolemia: roles of thyroid hormones, metabolites, and agonists
Bornyl Derivatives of p-(Benzyloxy) Phenylpropionic Acid: In Vivo Evaluation of Antidiabetic Activity
Source and Composition in Amino Acid of Dietary Proteins in the Primary Prevention and Treatment of CKD
Using Metalloporphyrins to Preserve β Cell Mass and Inhibit Immune Responses in Diabetes
Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy
Skeletal muscle reprogramming by breast cancer regardless of treatment history or tumor molecular subtype
Mono-and Polyunsaturated Fatty Acids Counter Palmitate-Induced Mitochondrial Dysfunction in Rat Skeletal Muscle Cells
The Adipose Tissue
Pathophysiology of melanocortin receptors and their accessory proteins
Exercise and rehabilitation of older horses
An Evaluation of Alzheimer’s Disease-related Pathology in Two Different Models of Diabetes in Immune-challenged Mice
G protein-coupled receptors as targets for improving beta-cell function in acute and chronic conditions of glucose intolerance
Docosanoids and elovanoids from omega-3 fatty acids are pro-homeostatic modulators of inflammatory responses, cell damage and neuroprotection
Determining the Physiological Contribution of Adipocyte Subpopulations
Effects of non-surgical periodontal therapy on plasma level of reactive oxygen metabolites and glycemic status in type-2 diabetic patients with chronic …
The fructose-2, 6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC
Impact of Metabolic Surgery in Cancer Prevention/Impacto da Cirurgia Metabólica na Prevenção de Cancro
Metabolic acidosis of chronic kidney disease
Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments
The multifaceted role of eosinophils in adipose tissue: from metabolism to allergy
Epistemic modals in academic English
β-Arrestin based receptor signaling paradigms: potential therapeutic targets for complex age-related disorders
Endocrine-disrupting chemicals and fatty liver disease
Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity
Anti-Hyperglycemic and Anti-Oxidant Activities of Ethanolic Extract of Lantana Camara Leaves
Recent advances in c-Jun N-terminal kinase (JNK) inhibitors
12 Metabolic Interventions
Determining the role of pancreatic alpha-cell autophagy in intra-cellular glucagon turnover and its modulation as an anti-diabetic therapy.
The Maladaptive Response of Adipose Tissue to High Fat Diet Feeding
Public health nutrition intervention to enhance healthy eating and lifestyle modification among Lebanese women with Polycystic Ovarian Syndrome
Expression of thyroglobulin by regulatory T cells in thyroid tissue
The Effect of the MNRI Method on Neurotransmitter Biomarkers of Individuals with Neurodevelopmental Disorders
Investigation of S1P and S1P Signaling in Adipocytes and Adipocyte-Breast Cancer Cell Interaction
Pharmacological actions of glucagon-like peptide-1, gastric inhibitory polypeptide, and glucagon
Identification of Shared Molecular Pathways and Networks between Alzheimer’s Disease and Type 2 Diabetes
Diabetes Risk Status and Physical Activity in Pregnant Women: US BRFSS 2011, 2013, 2015, 2017
Dietary interventions in C57BL/6 mice and their interplay with selected metabolic and genetic parameters
Polyphenols in diabetic vascular complications: from mechanisms to identification of therapeutic targets
Microbiota reprogramming for treatment of alcohol-related liver disease
Tetrahydro-iso-alpha acids antagonize estrogen receptor alpha activity in MCF-7 breast cancer cells
The innate immune kinase IKKε as a novel regulator of PSAT1 and serine metabolism
Burn Shock and Resuscitation: Many Priorities, One Goal
Protective effect of EX-527 against high-fat diet-induced diabetic nephropathy in Zucker rats
Transcriptional and translational regulators: Roles in development and function of innate-like and adaptive regulatory T cells
Metabolic Therapy for Age-Dependent Impaired Wound Healing
Complete nurse’s guide to diabetes care
Characterisation of the relationship between Heme-oxygenase-1 and adiponectin
Effect of dietary soy protein and oils containing omega-3 fatty acids on disease and renal oxylipins in polycystic kidney disease
The Leucine Factor Diet: The Scientifically-Proven Approach to Combat Sugar, Burn Fat and Build Muscle
Systems Biology Analysis of the Fate and Effects of Endocrine Disrupting Chemicals in Models of Adipose Tissue and the Gut Microbiota
How to Live: The groundbreaking lifestyle guide to keep you healthy, fit and free of illness
Effects of Synthetic Ligands on Heterodimer Pairs Regarding Full-Length Human PPARa, RXRa and LXRa
Impact of n-3 Polyunsaturated Fatty Acids on Adipose Tissue Inflammation and Metabolic Control in Severely Obese Patients
Current endoscopic/laparoscopic bariatric procedures
A History of Flexible Gastrointestinal Endoscopy
Kick Diabetes Essentials: The Diet and Lifestyle Guide
ROLE OF THE LONG PENTRAXIN 3 (PTX3) IN CARDIOMETABOLIC DISEASES
Metformin Pharmacogenomics: Functional Genomics of CDC25b and TPD54 Regulation of Metformin Anticancer Response in Breast Cancer
The Impact of Obesity on Proteins Involved in Drug Disposition
IKK Family Kinases Regulate Cell Growth, Metabolism and Autophagy by Phosphorylation of Key Substrates
The Aryl Hydrocarbon Receptor and Diet-Induced Obesity: An Investigation of How the Canonical Toxicant Receptor Modulates the Obese State via Activation and …
Prognostic Biomarkers of Periodontal Disease
Breast cancer associated muscle fatigue: Novel targets to improve survival and quality of life
The Banting Solution: Your low-carb guide to permanent weight loss
Defining the Role of Autophagy Kinase ULK1 Signaling in Therapeutic Response of Tuberous Sclerosis Complex to mTOR Inhibitors
RIBOSWITCH: AN AREA OF NOVEL BREAKTHROUGH IN RNA WORLD
DNA Methylation Dynamics and Epigenetic Memory in Highly Metabolic Mammalian Organs
Your Body in Balance: The New Science of Food, Hormones, and Health
Study of the role of the carotid sinus nerve in inflammation: electrostimulation of the carotid sinus nerve in mice attenuates inflammation by acting on the hypothalamic …
Analysis of secondary metabolism in marine Actinobacteria: searching for novel compounds
Mechanisms of CD4+ regulatory T cell heterogeneity in health and disease
Endoscopy, An Issue of Surgical Clinics, E-Book
Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation
DHA at nutritional doses restores insulin sensitivity in skeletal muscle by preventing lipotoxicity and inflammation
insulin resistance in cirrhosis: prolonged reduction of hyperinsulinemia normalizes insulin sensitivity
Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice
ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice
insulin resistance associated to obesity: the link TNF-alpha
Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes
Adipose tissue cytokines, insulin sensitivity, inflammation, and cardiovascular outcomes in end-stage renal disease patients
Exercise-induced increase in muscle insulin sensitivity
Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after single bout of exercise
Effect of the volume and intensity of exercise training on insulin sensitivity
Reversal of diet‐induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS‐1 serine phosphorylation
Effect of calorie restriction with or without exercise on insulin sensitivity, β-cell function, fat cell size, and ectopic lipid in overweight subjects
Acute physical exercise reverses S‐nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet‐induced obese Wistar rats
Deficiency of a β-arrestin-2 signal complex contributes to insulin resistance
Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet
AMPK and exercise: glucose uptake and insulin sensitivity
The impact of pegvisomant treatment on substrate metabolism and insulin sensitivity in patients with acromegaly
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes
(-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice
Irs1 serine 307 promotes insulin sensitivity in mice
Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet–fed mice
Increased GLUT-4 translocation mediates enhanced insulin sensitivity of muscle glucose transport after exercise
Acute oxidative stress can reverse insulin resistance by inactivation of cytoplasmic JNK
Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements
Bilirubin increases insulin sensitivity by regulating cholesterol metabolism, adipokines and PPARγ levels
Adenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15
Pegvisomant improves insulin sensitivity and reduces overnight free fatty acid concentrations in patients with acromegaly
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release
Acute exercise reverses aged-induced impairments in insulin signaling in rodent skeletal muscle
The cannabinoid Δ 9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity
Long-term monitoring of insulin sensitivity in growth hormone-deficient adults on substitutive recombinant human growth hormone therapy
Chronic caffeine intake reverses age-induced insulin resistance in the rat: effect on skeletal muscle Glut4 transporters and AMPK activity
Effect of physical exercise on insulin sensitivity and responsiveness to insulin in humans
Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy
Iron overload and non-alcoholic fatty liver disease.
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling
Exercise training prevents maturation-induced decrease in insulin sensitivity
Preconception diet or exercise intervention in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring
Influence of commonly employed resistance exercise protocols on circulating IL-6 and indices of insulin sensitivity
Impact of octreotide, a long‐acting somatostatin analogue, on glucose tolerance and insulin sensitivity in acromegaly
Captopril restores insulin sensitivity in ob/ob Mouse Hearts
Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome
The phosphatidylinositol/AKT/atypical PKC pathway is involved in the improved insulin sensitivity by DHEA in muscle and liver of rats in vivo
Improved insulin sensitivity, preserved beta cell function and improved whole-body glucose metabolism after low-dose growth hormone replacement therapy …
Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity
Growth hormone replacement therapy and insulin sensitivity
Effect of physical activity on insulin resistance, inflammation and oxidative stress in diabetes mellitus
Galectin-12 enhances inflammation by promoting M1 polarization of macrophages and reduces insulin sensitivity in adipocytes
Prolonged increase in insulin-stimulated glucose transport in muscle after exercise
Effects of growth hormone and free fatty acids on insulin sensitivity in patients with type 1 diabetes
Alcohol consumption promotes mammary tumor growth and insulin sensitivity
Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic
Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients
Resistin and obesity-associated insulin resistance
Inhibition of lipolysis during acute GH exposure increases insulin sensitivity in previously untreated GH-deficient adults
Short-term administration of pegvisomant improves hepatic insulin sensitivity and reduces soleus muscle intramyocellular lipid content in young adults with type 1 …
Glucose and fat metabolism in acromegaly: from mice models to patient care
Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism
Chronic N-acetylcysteine prevents fructose-induced insulin resistance and hypertension in rats
Comparison among different insulin sensitivity indices in obese patients
Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis
The effects of a specific growth hormone antagonist on overnight insulin requirements and insulin sensitivity in young adults with Type 1 diabetes mellitus
Prowashonupana barley dietary fibre reduces body fat and increases insulin sensitivity in Caenorhabditis elegans model
L-4f Restores insulin sensitivity And Attenuates Adiposity In Diabetic Obese Mice By Increasing Adiponectin, pAMPK And pAKT Levels And Decreasing Nuclear …
Effects of growth hormone on lipid metabolism in humans
Marked insulin resistance in obese spontaneously hypertensive rat adipocytes is ameliorated by in vivo but not in vitro treatment with moxonidine
Treating diabetes by blocking a vascular growth factor
Improvement of insulin response in the streptozotocin model of insulin-dependent diabetes mellitus. insulin response with and without a long-acting insulin treatment
Activation of nuclear receptor NR5A2 increases Glut4 expression and glucose metabolism in muscle cells
The sensory nitrergic nature of the hepatic insulin sensitizing substance mechanism in conscious rabbits
New insight into the mechanism by which acute physical exercise ameliorates insulin resistance
The effect of metformin on ovarian stimulation and in vitro fertilization in insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross …
PAQRs: a counteracting force to ceramides?
Stevioside ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by downregulating the NF-κB pathway
Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice
The role of aldosterone in cardiovascular disease in people with diabetes and hypertension: an update
Serum total and high molecular weight adiponectin levels are correlated with the severity of diabetic retinopathy and nephropathy
Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM
Propranolol improves impaired hepatic phosphatidylinositol 3-kinase/akt signaling after burn injury
Invited review: Effects of acute exercise and exercise training on insulin resistance
Central leptin acutely reverses diet-induced hepatic insulin resistance
Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1α: implications for metabolic disease
Effects of fasting and refeeding on insulin receptors and glucose metabolism in rat adipocytes
Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone
Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
Viewpoints on the way to the consensus session: where does insulin resistance start? The adipose tissue
Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice
Caffeic acid phenethyl ester regulates PPAR’s levels in stem cells-derived adipocytes
The frequency of daily ethanol consumption influences the effect of ethanol on insulin sensitivity in rats fed a high-fat diet
Early intensive insulin treatment for induction of long‐term glycaemic control in type 2 diabetes
insulin release, peripheral insulin resistance and muscle function in protein malnutrition: a role of tricarboxylic acid cycle anaplerosis
1-Deoxynojirimycin isolated from a Bacillus subtilis stimulates adiponectin and GLUT4 expressions in 3T3-L1 adipocytes
Amyloid-β induces hepatic insulin resistance in vivo via JAK2
Muscle long‐chain acyl CoA esters and insulin resistance
CXCL5 drives obesity to diabetes, and further
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
From excess adiposity to insulin resistance: the role of free fatty acids
Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) improves skeletal muscle mitochondrial function and insulin sensitivity
12 insulin treatment of non-insulin-dependent diabetes mellitus
Involvement of the PA28γ-dependent pathway in insulin resistance induced by hepatitis C virus core protein
The osteoblast: an insulin target cell controlling glucose homeostasis
High dietary protein intake, reducing or eliciting insulin resistance?
Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins
Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance
Knockdown of LYRM1 rescues insulin resistance and mitochondrial dysfunction induced by FCCP in 3T3-L1 adipocytes
Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat
Effect of insulin on glucose transport and metabolism in adipose tissue and skeletal muscle of hypophysectomized rats
Antihypertensive drugs and insulin resistance in obesity
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
Curative and β cell regenerative effects of α1-antitrypsin treatment in autoimmune diabetic NOD mice
Hyperglycemia associated with pasireotide: results from a mechanistic study in healthy volunteers
Analysis of FOXO1A as a candidate gene for type 2 diabetes
Adipocyte JAK2 mediates hepatic insulin sensitivity and the diabetogenic action of Growth Hormone
Sex steroids and insulin resistance
Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters
Lipid-induced metabolic dysfunction in skeletal muscle
Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation
Effects of GH replacement therapy in adults on serum levels of leptin and ghrelin: the role of lipolysis
Inhibition of the rise in FFA by Acipimox partially prevents GH-induced insulin resistance in GH-deficient adults
Diacylglycerol-mediated insulin resistance
Exercise-induced galanin release facilitated GLUT4 translocation in adipocytes of type 2 diabetic rats
Glycosphingolipids and insulin resistance
The adrenal and the metabolic syndrome
Growth hormone and insulin resistance
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
Serum resistin concentrations in growth hormone–deficient children during growth hormone replacement therapy
Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle
Metabolic Mechanisms of Muscle insulin Resistance
Comment on: Harrison et al. β-Cell function preservation after 3.5 years of intensive diabetes therapy. Diabetes Care 2012; 35: 1406–1412
Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults
Adiponectin levels during low‐and high‐fat eucaloric diets in lean and obese women
0341: AMPK exerts an insulin-sensitizing effect on cardiac glucose uptake by multiple molecular mechanisms including cytoskeleton reorganization
Sphingolipids and insulin resistance: the five Ws
Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats
insulin RESISTANCE IN THE HORSE
The metabolic syndrome, IGF-1, and insulin action
Evaluation of the Effect of Dehydroepiandrostrone (DHEA) on insulin sensitivity in IGT Patients
Effects of single bout of very high-intensity exercise on metabolic health biomarkers in overweight/obese sedentary men
Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice
Effect of growth hormone (GH) on fasting and postprandial metabolism in GH deficiency
Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and …
Postprandial but not fasting insulin resistance is an early identifier of dysmetabolism in overweight subjects
PEDF-induced alteration of metabolism leading to insulin resistance
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice
Ceramides–lipotoxic inducers of metabolic disorders
Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance
Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans
Skeletal muscle as a metabolic target for growth hormone
Effects of DHEA on diabetes mellitus
Incretin-based therapies for type 2 diabetes mellitus: effects on insulin resistance
Improvement of glucose homeostasis after weight loss in obese children
Serum N-Acetyl-β-D-Glucosaminidase, Activity in a Genetic Rat Model of Non-insulin-Dependent Diabetes Mellitus
Endoplasmic reticulum stress and hepatic lipid metabolism
Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes
Impact of different bariatric surgical procedures on insulin action and β-cell function in type 2 diabetes
A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats
Anti-Ageing Cure
Effects of exenatide, insulin, and pioglitazone on liver fat content and body fat distributions in drug-naive subjects with type 2 diabetes
New approach in the treatment of T2DM and metabolic syndrome (focus on a novel insulin sensitizer)
Somatropin and Glucose Homeostasis
The Role of Lipid Metabolism in Altered insulin sensitivity in Endocrine Disease
Inflammation, dyslipidaemia, diabetes and PPars: pharmacological interest of dual PPARα and PPARγ agonists
Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring
A ceramide-centric view of insulin resistance
Body Composition in Adolescents with Type 1 Diabetes: Aspects of Glycaemic Control and insulin sensitivity
Effects of growth hormone on glucose and fat metabolism in human subjects
Glycosphingolipids and insulin resistance
Biozentrum, Div. of Pharmacology/Neurobiology, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland
TNF-α as an Adipokine
The clinical relevance of pancreatic B-cell hyperplasia, hyperinsulinism and insulin ininsulin sensitivity in non-insulin dependent diabetes mellitus
Central role of the adipocyte in the insulin-sensitising and cardiovascular risk modifying actions of the thiazolidinediones
Pioglitazone enhances expression of genes involved in mitochondrial oxidative metabolism in skeletal muscle of women with polycystic ovary syndrome …
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Obesity, blood pressure, and renal sodium handling
Hepatic Bax inhibitor-1 inhibits IRE1α and protects from obesity-associated insulin resistance and glucose intolerance
HIV-associated lipodystrophy syndrome
Comparison of two different sprint interval training work-to-rest ratios on acute inflammatory responses
Red wine mimic can fight diabetes
ORALS: DISRUPTION IN SIGNALING LEADING TO insulin RESISTANCE
The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance
PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression
Effect Of Vasodilatory β‐Adrenoceptor Blockers On Cardiovascular Haemodynamics In Anaesthetized Rats
Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics
Patterns of glucose and lipid abnormalities in black NIDDM subjects
The association between blood pressure and glucosylceramides in spontaneously hypertensive rats
Ganglioside GM3 as a gatekeeper of obesity-associated insulin resistance: Evidence and mechanisms
Glucose Toxicity and insulin Resistance in NIDDM
Estrogen: an emerging regulator of insulin action and mitochondrial function
Decreased whole body lipolysis as a mechanism of the lipid-lowering effect of pioglitazone in type 2 diabetic patients
Diets and nonalcoholic fatty liver disease: the good and the bad
Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistance
insulin resistance: A new consequence of altered carotid body chemoreflex?
Invited review: effect of acute exercise on insulin signaling and action in humans
Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in middle-aged men
Ceramides and glucosylceramides are independent antagonists of insulin signaling
Growth hormone and glucose homeostasis
Dose-response effects of free fatty acids on glucose and lipid metabolism during somatostatin blockade of growth hormone and insulin in humans
Prevention and Reversal of Diabetes
The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle
Exercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats
The impact of adipose tissue on insulin resistance in acromegaly
Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
Ceramide kinase deficiency improves diet-induced obesity and insulin resistance
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes
Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes
Role of macrophage tissue infiltration in obesity and insulin resistance
Oat consumption reduced intestinal fat deposition and improved health span in Caenorhabditis elegans model
Brain adipocytokine action and metabolic regulation
Physical inactivity, insulin resistance, and the oxidative-inflammatory loop
Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects
insulin-like growth factors and insulin: at the crossroad between tumor development and longevity
Glucose Toxicity and insulin Resistance
The acute and residual effect of a single exercise session on meal glucose tolerance in sedentary young adults
Mouse models of insulin resistance
Increased hepatic insulin action in diet-induced obese mice following inhibition of glucosylceramide synthase
TWEAK prevents TNF-α-induced insulin resistance through PP2A activation in human adipocytes
insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats
Membrane microdomains and insulin resistance
Bypass of the duodenum improves insulin resistance much more rapidly than sleeve gastrectomy
IRS proteins and the common path to diabetes
Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice
Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium
Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice
Metformin Suppresses Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-+Leprdb/+Leprdb Mice
Effect of exercise training on A‐FABP, lipocalin‐2 and RBP4 levels in obese women
Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species
Absence of melatonin induces night-time hepatic insulin resistance and increased gluconeogenesis due to stimulation of nocturnal unfolded protein response
The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism
N− 3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells
Living without insulin: the role of leptin signaling in the hypothalamus
The twists and turns of sphingolipid pathway in glucose regulation
Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance
Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion
Novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets
Novel mechanisms of insulin resistance and weight gain in diet induced obesity
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
An anti-aging drug today: from senescence-promoting genes to anti-aging pill
An ascochlorin derivative, AS-6, potentiates insulin action in streptozotocin diabetic mice and rats
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
Recombinant human growth hormone and rosiglitazone for abdominal fat accumulation in HIV-infected patients with insulin resistance: a randomized, double …
Adipocytes as regulators of energy balance and glucose homeostasis
Bcl10 links saturated fat overnutrition with hepatocellular NF-κB activation and insulin resistance
Thermogenesis and related metabolic targets in anti-diabetic therapy
Is reactivation of autophagy a possible therapeutic solution for obesity and metabolic syndrome?
Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training
Enhanced glucose metabolism in cultured human skeletal muscle after Roux-en-Y gastric bypass surgery
Toll‐like receptors 2 and 4 impair insulin‐mediated brain activity by interleukin‐6 and osteopontin and alter sleep architecture
Impact of divergent effects of astaxanthin on insulin signaling in L6 cells
Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in
insulin Resistance and the Metabolic Syndrome
RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27
Self-adjusting synthetic gene circuit for correcting insulin resistance
Reduction of adiposity with prolonged growth hormone treatment in old obese rats: effects on glucose handling and early insulin signaling
Role of endogenous androgen against insulin resistance and athero-sclerosis in men with type 2 diabetes
T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance
In vivo mutagenesis of the insulin receptor
Hypertension–a visceral afferent problem
Hepatic ERK activity plays a role in energy metabolism
Prior exercise increases phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle
insulin resistance and response to telaprevir plus peginterferon α and ribavirin in treatment-naive patients infected with HCV genotype 1
Adipose tissue as a secretory organ: from adipogenesis to the metabolic syndrome
Gangliosides in cell recognition and membrane protein regulation
Effects of DHA-enriched fish oil on monocyte/macrophage activation marker sCD163, asymmetric dimethyl arginine, and insulin resistance in type 2 diabetic patients
insulin-sensitising agents: beyond thiazolidinediones
The Short-term Effects of insulin, Metformin and insulin-Metformin Combination on the Liver Morphology in High Fat Diet/Streptozotocin Induced Diabetic Albino …
Neutralizing Th2 inflammation in neonatal islets prevents β-cell failure in adult IUGR rats
Lower visceral and subcutaneous but higher intermuscular adipose tissue depots in patients with growth hormone and insulin-like growth factor I excess due to …
Phosphorylation of IRS proteins, insulin action, and insulin resistance
Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?
Anti-diabetic effect of 3-hydroxy-2-naphthoic acid, an endoplasmic reticulum stress-reducing chemical chaperone
Exercise training increases intramyocellular lipid and oxidative capacity in older adults
Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism
Sensing’the link between type 1 and type 2 diabetes
Effect of GH on human skeletal muscle lipid metabolism in GH deficiency
Diabetes, growth hormone-insulin-like growth factor pathways and association to benign prostatic hyperplasia
Effects of gender and GH secretory pattern on sterol regulatory element-binding protein-1c and its target genes in rat liver
Effects of GH in human muscle and fat
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
Validation of anti-aging drugs by treating age-related diseases
Dehydroepiandrosterone increases β-cell mass and improves the glucose-induced insulin secretion by pancreatic islets from aged rats
Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice
Metabolic inflammation-associated IL-17A causes non-alcoholic steatohepatitis and hepatocellular carcinoma
mTOR couples cellular nutrient sensing to organismal metabolic homeostasis
Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways
One bout of exercise alters free-living postprandial glycemia in type 2 diabetes
Maternal breastfeeding history and Alzheimer’s disease risk
Identification of potent and selective glucosylceramide synthase inhibitors from a library of N-alkylated iminosugars
Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer’s disease
mTOR and the control of whole body metabolism
The metabolic syndrome as a vicious cycle: does obesity beget obesity?
Silencing CCR2 in macrophages alleviates adipose tissue inflammation and the associated metabolic syndrome in dietary obese mice
Early intranasal insulin therapy halts progression of neurodegeneration: progress in Alzheimer’s disease therapeutics
The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations
Targeting AMP-activated protein kinase as a novel therapeutic approach for the treatment of metabolic disorders
Hypothalamic inflammation in the control of metabolic function
Dehydroepiandrosterone decreases elevated hepatic glucose production in C57BL/KsJ-db/db mice
Metabolic consequences of androgen deprivation therapy for prostate cancer
Endocrine, metabolic, and immunologic components of HIV infection
Fasting-induced lipolysis and hypothalamic insulin signaling are regulated by neuronal glucosylceramide synthase
GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus
Molecular links between obesity and cardiovascular disease
Sensitization by insulin of the anaphylactoid inflammation in rats
The relationship between adipose tissue-derived hormones and gestational diabetes mellitus (GDM)
An explanation of the Equine Metabolic Syndrome, insulin resistance and the risk of laminitis
Effects of DHEA on metabolic and endocrine functions of adipose tissue
EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet
Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.
Metformin: actions and indications for use in non-insulin-dependent diabetes mellitus
Effects of clenbuterol on insulin resistance in conscious obese Zucker rats
Ganglioside GM1 contributes to the state of insulin resistance in senescent human arterial endothelial cells
The impact of Heat Shock Protein 72 expression on mitochondrial function and insulin action
AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes
insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load
Influence of endurance training on central sympathetic outflow to skeletal muscle in response to a mixed meal
Dietary antioxidants and glucose metabolism
Potential Mechanisms for Amelioration of Type 2 Diabetes Following Bariatric Surgery
Current and emerging aspects of diabetes mellitus in acromegaly
Androgen deficiency and mitochondrial dysfunction: implications for fatigue, muscle dysfunction, insulin resistance, diabetes, and cardiovascular disease
Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS) 1 …
The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasis
Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis
GH replacement causing acute hyperglycaemia and ketonuria in a type 1 diabetic patient
Sphingolipids: the nexus between Gaucher disease and insulin resistance
insulin, insulin resistance and platelet function: similarities with insulin effects on cultured vascular smooth muscle cells
Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes
The importance of the cellular stress response in the pathogenesis and treatment of type 2 diabetes
insulin down-regulates resistin mRNA through the synthesis of protein (s) that could accelerate the degradation of resistin mRNA in 3T3-L1 adipocytes
Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial
insulin resistance is associated with impaired cardiac sympathetic innervation in patients with heart failure
Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentrations in women with type 2 diabetes
Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesity
Caffeine, insulin resistance, and hypertension
insulin receptor knockout mice
Oleanolic acid reduces markers of differentiation in 3T3-L1 adipocytes
Treatment of non-alcoholic fatty liver disease
Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation
The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome
Serum dehydroepiandrosterone sulfate concentration and carotid atherosclerosis in men with type 2 diabetes
Docosahexaenoic acid, inflammation, and bacterial dysbiosis in relation to periodontal disease, inflammatory bowel disease, and the metabolic syndrome
Adiponectin and high-density lipoprotein: a metabolic association through thick and thin
Leptin opposes insulin‘s effects on fatty acid partitioning in muscles isolated from obese ob/obmice
Comparative proteomic study of fatty acid-treated myoblasts reveals role of Cox-2 in palmitate-induced insulin resistance
Interactions of exercise training and α-lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats
Dehydroepiandrosterone Suppresses Elevated Hepatic Glucose-6-phosphatase mRNA Level in C57BL/KsJ-db/db Mice
Targeting the AMPK pathway for the treatment of Type 2 diabetes
The role of organelle stresses in diabetes mellitus and obesity: implication for treatment
The influence of alpha-tocopherol supplementation on plasma concentration of this vitamin and insulin in sedentary or physically trained rats
Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentration in male patients with type 2 diabetes: a possible link …
Management of gestational diabetes
Assessment of partially deoxygenated deoxynojirimycin derivatives as glucosylceramide synthase inhibitors
Hepatic steatosis: a benign disease or a silent killer
insulin resistance, inflammation, and the IKK/IκB/NF-κB pathway
Hyperandrogenism induces a proinflammatory TNFα response to glucose ingestion in a receptor-dependent fashion
Consequences of growth hormone deficiency for intermediary metabolism and effects of replacement
Influence of metformin on glucose intolerance and muscle catabolism following severe burn injury
AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives
Skeletal muscle contraction stimulates capillary recruitment and glucose uptake in insulin-resistant obese Zucker rats
Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors
Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats
ELEVATED INTERLUKIN-6 LEVELS AS A CONSEQUENCE, NOT THE CAUSE OF OBESITY AND insulin RESISTANCE
Changes of serum retinol binding protein 4 levels following 8 weeks moderate aerobic exercise
Compounds of the sphingomyelin-ceramide-glycosphingolipid pathways as secondary messenger molecules: new targets for novel therapies for fatty liver disease …
Effects of individual fatty acids on glucose uptake and glycogen synthesis in soleus muscle in vitro
Gone with the Wnts: β-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism
Long-chain polyunsaturated fatty acids amend palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes
Hyperandrogenism sensitizes mononuclear cells to promote glucose-induced inflammation in lean reproductive-age women
insulin resistance, inflammation, and the IKK/IkB/NF-kB pathway
Total and high-molecular-weight adiponectin and risk of incident diabetes in older people
New mechanisms by which physical exercise improves insulin resistance in the skeletal muscle
Adrenal androgens and aging
An Antiinflammatory and Reactive Oxygen Species Suppressive Effects of an Extract of Polygonum Cuspidatum Containing Resveratrol
Metabolomics applied to diabetes research: moving from information to knowledge
AMP-activated protein kinase and metabolic control
Acceleration training for managing nonalcoholic fatty liver disease: a pilot study
Immune cell crosstalk in obesity: a key role for costimulation?
A safety evaluation of canagliflozin: a first-in-class treatment for type 2 diabetes
Dehydroepiandrosterone (DHEA)—a precursor steroid or an active hormone in human physiology (CME)
The role of the angiotensin system in cardiac glucose homeostasis
Glycogen synthase kinase-3 and mammalian target of rapamycin pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets
A HaloTag-based small molecule microarray screening methodology with increased insulin sensitivity and multiplex capabilities
An insulin receptor peptide (1135-1156) stimulates guanosine 5′-[γ-thio] triphosphate binding to the 67 kDa G-protein associated with the insulin receptor
Identification of ganglioside GM3 molecular species in human serum associated with risk factors of metabolic syndrome
Adiponectin, leptin, and erythrocyte sodium/lithium countertransport activity, but not resistin, are related to glucose metabolism in growth hormone-deficient adults
Hyperandrogenism sensitizes leukocytes to hyperglycemia to promote oxidative stress in lean reproductive-age women
Diethyl Hexyl Phthalate (DEHP) is associated with insulin resistance in adipose tissue of male rat: Protective role of antioxidant vitamins (C & E)
Effects of 8 weeks high intensity aerobic exercise on serum retinol binding protein 4 levels in female athletes
The adipokines resistin, leptin, PAI-1 and RBP4 induce degradation of IRS-1 in megakaryocytes and produc-tion of insulin-resistant platelets
Postdinner resistance exercise improves postprandial risk factors more effectively than predinner resistance exercise in patients with type 2 diabetes
Skeletal muscle lipid metabolism with obesity
The role of atypical and conventional PKC in dehydroepiandrosterone-induced glucose uptake and dexamethasone-induced insulin resistance
APPL1: role in adiponectin signaling and beyond
Effect of DHEA on endocrine functions of adipose tissue, the involvement of PPARγ
PEDF attenuates insulin-dependent molecular pathways of glucose homeostasis in skeletal myocytes
Smoking and diabetes
7 insulin action and substrate competition
Adipose tissue hypoxia and low-grade inflammation: a possible mechanism for ethanol-related glucose intolerance?
OPE WO OD
Fibroblast growth factor 21 as an emerging therapeutic target for type 2 diabetes mellitus
Dehydroepiandrosterone increases b-cell mass and improves the glucose-induced insulin secretion by pancreatic islets from aged rats
Aspartame downregulates 3T3-L1 differentiation
Serum ghrelin levels in acromegaly: effects of surgical and long-acting octreotide therapy
Regulation of β‐cell mass and function by the Akt/protein kinase B signalling pathway
Effect of dehydroepiandrosterone administration on recovery from mix-type exercise training-induced muscle damage
Type II SOCS as a feedback repressor for GH-induced Igf1 expression in carp hepatocytes
As a matter of fat
The aging rodent: insulin resistance, obesity, and metabolic compensation
Metabolic Effects of Omega-3 Long-Chain Polyunsaturated Fatty Acids
The insulin growth factor system and nutrition in adulthood and aging
The role of glycosphingolipids in insulin signaling and lipid metabolism
Metabolic inflexibility: when mitochondrial indecision leads to metabolic gridlock
Role of JTT-501, a new insulin sensitiser, in restoring impaired GLUT4 translocation in adipocytes of rats fed a high fat diet
insulin and GH Signaling in Human Skeletal Muscle In
Meal-induced hormone responses in a rat model of Roux-en-Y gastric bypass surgery
The peroxide dilemma: opposing and mediating insulin action
An increase in the omega-6/omega-3 fatty acid ratio increases the risk for obesity
Metformin prevents embryonic resorption induced by hyperandrogenisation with dehydroepiandrosterone in mice
Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells
High glucose and insulin inhibit VSMC MKP-1 expression by blocking iNOS via p38 MAPK activation
insulin as an anti-inflammatory and antiatherosclerotic hormone
Facilitative glucose transporters
Fisetin up-regulates the expression of adiponectin in 3T3-L1 adipocytes via the activation of silent mating type information regulation 2 homologue 1 (SIRT1) …
GLUT4 overexpression in db/db mice dose-dependently ameliorates diabetes but is not a lifelong cure
The management of adult growth hormone deficiency syndrome
Adipose tissue: an endocrine organ playing a role in metabolic regulation
Impact of diabetes mellitus on lymphocyte GRK 2 protein levels in patients with heart failure
Environmental determinants of polycystic ovary syndrome
Cardiac fatty acid oxidation in heart failure associated with obesity and diabetes
Impaired glucose metabolism and reduced insulin clearance in elderly hypertensives
A role for sphingolipids in the pathophysiology of obesity-induced inflammation
Effects of physical training with different intensities of effort on lipid metabolism in rats submitted to the neonatal application of alloxan
Insights and Future Directions
Journal of the International Bariatric Club
Experimental models of high fat obesity and leucine supplementation
Glycosphingolipids and kidney disease
Adipose tissue redistribution and ectopic lipid deposition in active acromegaly and effects of surgical treatment
Disorders of glucose metabolism in the context of human immunodeficiency virus infection
A complex role for adipose tissue macrophages
Fibroblast growth factor 21 is induced by endoplasmic reticulum stress
Diethyl hexyl phthalate-induced changes in insulin signaling molecules and the protective role of antioxidant vitamins in gastrocnemius muscle of adult male rat
Metabolic and ovarian consequences of perinatal sex steroid programming
Growth hormone-mediated breakdown of body fat: effects of GH on lipases in adipose tissue and skeletal muscle of old rats fed different diets
Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation
Steatosis and hepatitis C
Fighting Alzheimer’s disease and type 2 diabetes: pathological links and treatment strategies
insulin regulates retinol dehydrogenase expression and all-trans-retinoic acid biosynthesis through FoxO1
Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha.
Glucagon like peptide-1 (GLP-1) dynamics following bariatric surgery: a Signpost to a new frontier
The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men
Treatment of genetically obese (ob/ob) mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin (AMP-DNM) increases fat oxidation …
Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes
Steatosis in chronic hepatitis C: why does it really matter?
Omega-3 fatty acids and skeletal muscle health
Adipokines and insulin resistance
Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE* 3 Leiden and low …
Association of insulin-related serum factors with colorectal polyp number and type in adult males
Increased insulin receptor signaling and glycogen synthase activity contribute to the synergistic effect of exercise on insulin action
LOSS OF SKELETAL MUSCLE PKCθ PROTECTS AGAINST THE PATHOGENESIS OF insulin RESISTANCE
Treatment of genetically obese mice with the iminosugar AMP-DNM increases fat oxidation and decreases food intake
Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals
Metabolic surgery in Zucker rats influenced miRNA, caveolin-1 expression and lipid metabolism
Sarcopenia in patients with chronic liver disease: can it be altered by diet and exercise?
Alterations in soleus muscle gene expression associated with a metabolic endpoint following exercise training by lean and obese Zucker rats
“Weighing” the effects of exercise and intrinsic aerobic capacity: are there beneficial effects independent of changes in weight?
Obesity and the skin: skin physiology and skin manifestations of obesity
Genome-wide pathway analysis for diabetic nephropathy in type 1 diabetes
A critical appraisal of the predictive adaptive response hypothesis
Polar lipid derangements in type 2 diabetes mellitus: potential pathological relevance of fatty acyl heterogeneity in sphingolipids
Glycolytic and mitochondrial metabolism in pancreatic islets from MSG-treated obese rats subjected to swimming training
FOXO transcription factors: their clinical significance and regulation
The gut microbiota: the gateway to improved metabolism
Amlexanox suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss
Fat cells: afferent and efferent messages define new approaches to treat obesity
Use of Microarrays to Investigate the Transcriptional Effects of Protein Tyrosine Phosphatase IB (PTP1B): Implications for Diabetes and Obesity
Biological mechanisms linking obesity and cancer risk: new perspectives
Minimizing Obesity With Hormone Replacement Therapy
Control of homeostatic and pathogenic balance in adipose tissue by ganglioside GM3
Supplemental Data Article Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle insulin Resistance
Nutrition in Metabolic Syndrome Topic 24
Glucosylceramide synthase in the fat body controls energy metabolism in Drosophila
Androgens and Coronary Artery Disease
Impaired plasma fatty acid oxidation in extremely obese women
Serum phospholipid docosahexaenoic acid is inversely associated with arterial stiffness in metabolically healthy men
Emerging sodium/glucose co-transporter 2 inhibitors for type 2 diabetes
A view on sphingolipids and disease
Emerging role of the GH/IGF-I on cardiometabolic control
The importance of steatosis in chronic hepatitis C infection and its management: a review
Stimulation of human omental adipose tissue lipolysis by growth hormone plus dexamethasone
Could gestational diabetes mellitus be managed through dietary bioactive compounds? Current knowledge and future perspectives
Detection of HISS-dependent insulin action: method considerations
Depressed DHEA and increased sickness response behaviors in lame dairy cows with inflammatory foot lesions
Continuous and intermittent exercise training and glucose metabolism in neonatal alloxan administered rats
2012 New Investigator Award from the Neural Control and Autonomic Regulation (NCAR) Section of the American Physiological Society: The CNS glucagon …
Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity
The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment.
The Pathophysiological Importance of Nicotinamide Phosphoribosyltransferase as a Key NAD Biosynthesis Enzyme in Metabolic Homeostasis
Gene expression signature in adipose tissue of acromegaly patients
TOPIC 06–Diabetes, dyslipidemia, metabolism
Department of Metabolic Diseases
Glycosphingolipid synthesis inhibitor AMP. DNM lowers plasma cholesterol levels by promoting fecal cholesterol excretion without inhibiting cholesterol absorption
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired …
Physiopathological function of hematoside (GM3 ganglioside)
Reduced histone H3K9 acetylation of clock genes and abnormal glucose metabolism in ob/ob mice
Development and validation of a high-resolution capillary electrophoresis method for multi-analysis of ragaglitazar and arginine in Active Pharmaceutical Ingredients …
Relationship between low serum endogenous androgen concentrations and arterial stiffness in men with type 2 diabetes mellitus
Obesity, metabolic syndrome, and airway disease: a bioenergetic problem?
Mouse models to decipher the PI3K signaling network in human cancer
TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activity
From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis
Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver
WAT-free mice: diabetes without obesity
Regulation of Glut-4 Expression in Skeletal Muscle cells: The Roles of Nuclear Respiratory Factor-1 and calcium/calmodulin dependent protein Kinase
Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction
Fatty acid-induced atherogenic changes in extracellular matrix proteoglycans
Metabolic Actions of Growth Hormone
Effect of 1-deoxynojirimycin on cholesterol efflux through ABCA1-LXRα pathway in 3T3-L1 adipocytes
Mice heterozygous for the xanthine oxidoreductase gene facilitate lipid accumulation in adipocytes
New mechanisms contributing to hepatic steatosis: glucose, insulin, and lipid signaling
Prospects for pharmacologic inhibition of hepatic glucose production
Light-to-moderate ethanol feeding augments AMPK-α phosphorylation and attenuates SREBP-1 expression in the liver of rats
The effect of FoxO1 on glycemic control and skeletal muscle glucose uptake and lipid metabolism
DHEA in hair and glucose control in African-American adults
A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer’s disease
Identification of regulatory elements in the human adipose most abundant gene transcript-1 (apM-1) promoter: role of SP1/SP3 and TNF-α as regulatory pathways
Effect of electroacupuncture on inflammation in the obese zucker fatty rat model of metabolic syndrome
Loss of PDGF-B activity increases hepatic vascular
Exercise and postprandial glycemic control in type 2 diabetes
Association of serum dehydroepiandrosterone sulfate and cognition in older adults: sex steroid, inflammatory, and metabolic mechanisms.
insulin resistance states and insulin allergy
What’s New in Shock? January 2014
Inhibition of GSK3β by pharmacological modulation of sphingolipid metabolism occurs independently of ganglioside disturbance in a cellular model of Alzheimer’s …
The role of leptin in obesity and diabetes mellitus in dog
The evolution of Fox genes and their role in development and disease
Clinical aspects of growth hormone deficiency in adults
The many facets of PEDF in drug discovery and disease: a diamond in the rough or split personality disorder?
Fox genes in glucose homeostasis
Drugs in sport: a scientist–athlete’s perspective: from ambition to neurochemistry
Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-α and cycloheximide in a manner independent of STAT5A activation
Glucose control and the inflammatory response
Correlation between Serum Dehydroepiandrosterone Sulfate and Coronary Artery Disease in Middle-Aged and Elderly Men
Metabolic lessons from genetically lean mice
Dehydroepiandrosterone down-regulates the expression of peroxisome proliferator-activated receptor γ in adipocytes
Bibliography Current World Literature Vol 21 No 2 April 2010
VASCO DA GAMA UNIVERSITARY SCHOOL
Impact of light ethanol intake and of taurine, separately and together, on pathways of glucose metabolism in the kidney of diabetic rats
Long-term effects of laparoscopic Roux-en-Y gastric bypass on diabetes mellitus, hypertension and dyslipidaemia in morbidly obese patients
Lipidomics applications for disease biomarker discovery in mammal models
Newer therapies for diabetes management
Rapid and reversible induction of the longevity, anticancer and genomic effects of caloric restriction
Lipidomics as a principal tool for advancing biomedical research
Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue
mTORC1 and mTORC2 in energy homeostasis
Diet and longevity phenotype
Regulation of body weight
insulin Stimulated Lactate Production
Effect of cerebrocrast on body and organ weights, food and water intake, and urine output of normal rats
Glucose oxidation rates in fatty acid-perfused isolated working hearts from diabetic rats
Glycosphingolipids and atherosclerosis
Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes
Differential Regulation of IGF-1 and insulin Signaling by GRKs
Berberine suppresses proinflammatory responses through AMPK activation in macrophages
Role of novel Russian adaptogenic compounds in restoration of adrenal function
Endocrine function after bariatric surgery
Complex Roles of Macrophages in Lipid Metabolism and Metabolic Disease: A Dissertation
Abnormal cytokine and adrenocortical hormone regulation in myotonic dystrophy
Endoplasmic reticulum stress in nonalcoholic fatty liver disease
FOR APPROVAL
Mechanisms governing the health and performance benefits of exercise
25 Adipose Tissue as a Target for Dehydroepiandrosterone and Its Sulfate
Claims for the anabolic effects of growth hormone: a case of the emperor’s new clothes?
Role of n-3 polyunsaturated fatty acids in ameliorating the obesity-induced metabolic syndrome in animal models and humans
Regulatory role of natural killer T cells in diabetes
Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis
Pharmacological Treatments for Obesity-Related Hypertension
Absence of Melatonin Induces Night-Time Hepatic insulin Resistance and
PRE AND POSTDOCTORAL FELLOWSHIPS
Metabolic and endocrine adaptations to heat stress in lactating dairy cows
Molecular Aspects of Obesity and insulin Resistance in Metabolic Syndrome and Neurological Disorders
Serum dehydroepiandrosterone sulfate and risk for type 2 diabetes in older men and women: the Pro. VA Study
Application of the speed-duration relationship to normalize the intensity of high-intensity interval training
Dehydroepiandrosterone in intracellular infectious diseases and related pathogens
Investigating the role of mir-190, mir-200, and mir-8 inhibition of the GCS protein in HeLa cells and Drosophila melanogaster
Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity
Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1, 6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison …
Inhibition of forkhead box O1 protects pancreatic β-cells against dexamethasone-induced dysfunction
Obesity-related derangements in metabolic regulation
Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) guidelines on the treatment of hyperglycemia in Cushing’s syndrome and …
Identification of novel GH-regulated pathway of lipid metabolism in adipose tissue: a gene expression study in hypopituitary men
Effects of increased dietary cholesterol with carbohydrate restriction on hepatic lipid metabolism in Guinea pigs
Role of angiotensin II in hepatic inflammation through MAPK pathway: a review
T lymphopenia in genetically obese-diabetic Wistar fatty rats: effects of body weight reduction on T cells
Novel Strategies to Improve Metabolic Parameters and Precondition Diabetic Hearts Against Ischemia/reperfusion Injury
280 RETREATMENT WITH PEG-IFN ALPHA-2A PLUS RIBAVIRIN FOR 48 WEEKS IN CHRONIC HEPATITIS C GENOTYPE 2 AND 3 RELAPSERS TO A …
Can sedentary time attenuate the acute effect of exercise on insulin action?
Freedom from Disease: The Breakthrough Approach to Preventing Cancer, Heart Disease, Alzheimer’s, and Depression by Controlling insulin
Diabetes, oxidative stress and therapeutic strategies
T-cell-directed treatment strategies for Type 1 diabetes and the confounding role of inflammation
Gene expression in skeletal muscle after an acute intravenous GH bolus in human subjects: identification of a mechanism regulating ANGPTL4
Sequestosome 1/p62 and TRAF6 are necessary for Akt ubiquitination, translocation and activation
Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis
Alternative mechanism for anti-obesity effect of dehydroepiandrosterone: possible contribution of 11β-hydroxysteroid dehydrogenase type 1 inhibition in rodent …
Testosterone-dependent vascular arachidonic acid metabolism in the regulation of insulin resistance and blood pressure
Lipidomics: Novel insight into the biochemical mechanism of lipid metabolism and dysregulation-associated disease
Mechanisms Mediating Antidiabetic Effects of Serviceberry extracts, Curcumin, and Stilbenes
An in vitro study on the influence of the pituitary gland on insulin secretion in lean and genetically obese mice
Circadian integration of hepatic de novo lipogenesis and peripheral energy substrates utilization
An Investigation of Antioxidant and Antidiabetic Effect of Aqueous Leaf Extracts of Mucuna Pruriens
Hunger Free Forever: The New Science of Appetite Control
The effects of obesity and different modes of training on the skeletal muscle microvasculature
DHEA induces 11β-HSD2 by acting on CCAAT/enhancer-binding proteins
Studies on insulin secretion and glucose tolerance in experimental obesity and diabetes.
Sumona Ghosh Lester, Simona S. Ghanem, and Sonia M. Najjar
Determinants of evolving metabolic and cardiovascular benefit/risk profiles of rosiglitazone therapy during the natural history of diabetes: molecular mechanisms in the …
Activation of cyclic‐AMP response element binding protein contributes to adiponectin‐stimulated interleukin‐10 expression in raw 264.7 macrophages
Targeting mTOR Signaling Pathways in Liver Disease
Invited review: intracellular signaling in contracting skeletal muscle
Testosterone: a natural tonic for the failing heart?
Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase
Regulation of cytochrome P450 2B10 (CYP2B10) expression in liver by peroxisome proliferator-activated receptor-β/δ modulation of SP1 promoter occupancy
Clinical Physiopathology and Experimental Medicine
THE ROLE OF ER STRESS IN LIPOGENESIS AND insulin RESISTANCE IN RESPONSE TO OVER NUTRITION
Seasonal Adiposity and Delayed Ovulation in a Vespertilionid Bat, Scotophilus heathi: Role of Tumor Necrosis Factor‐α
Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition
Effect of adrenalectomy and corticosterone replacement on meal patterns of Zucker rats
Relationships Between the Features of Metabolic Syndrome and Fatty Acids in the Diet, Plasma, and Adipose Tissue of Healthy Older Adults
Fermented Soy Product Isoflavone Composition, and Role in Gene Responses in C57BL/6 Mice
LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with …
Conflict of interest: None declared.
Sistema de Informação de Ciência e Tecnologia (SICT) 2012-INSTITUIÇÕES
Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation
Endothelial relaxation mechanisms and oxidative stress are restored by atorvastatin therapy in ovariectomized rats
Formation and signaling actions of electrophilic lipids
The Sick Adipocyte Theory: The Forces of Clustering at Glance
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family
Effect of rapid weight loss with supplemented fasting on serum electrolytes, lipids, and blood pressure
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
Autoimmunity, dehydroepiandrosterone (DHEA), and stress
Articles Published in Brazilian Journals Relevant to Sports and Exercise Medicine; a Review
Comparison of Two Different Sprint Interval Training Work-to-Rest Ratios on Acute Metabolic and Inflammatory Responses
Beta-arrestin2 is involved in the increase of distal colonic contraction in diabetic rats
CNS and peripheral mechanisms by which voluntary running wheel exercise affects adiposity and glucose metabolism
Dehydroepiandrosterone inhibits CD40/CD40L expression on human umbilical vein endothelial cells induced by interferon gamma
Physical activity protects the human brain against metabolic stress induced by a postprandial and chronic inflammation
The Role of AMPKα in High-Glucose-Induced Dysfunction of Cultured Rat Mesangial Cells
β-Arrestin-mediated receptor trafficking and signal transduction
Immunoresolving lipid mediators and resolution of inflammation in aging
Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and …
Comparison of milk fatty acid responses during fish oil-and trans-10 cis-12 18: 2-induced milk fat depression in dairy ewes
JNK signalling in cancer: in need of new, smarter therapeutic targets
Adrenalectomy fails to stimulate brown adipose tissue metabolism in ob/ob mice fed glucose
Strategies for the management of patients with obesity
Effect of Adiponectin Overexpression on the Metabolic Phenotype of the Ceacaml-/-Mouse
Increased lipid absorption and transport in the small intestine of zucker obese rats
IRS-1 and vascular complications in diabetes mellitus
The Antiobesity Effect of Dehydroepiandrosterone (DHEA): Clinical Studies in the Canine Model
Worming to Complete the insulin/IGF-1 Signaling Cascade: A Dissertation
Cell-specific in vivo functions of glycosphingolipids: lessons from genetic deletions of enzymes involved in glycosphingolipid synthesis
Epigenetic regulation of glucose transporter 4 by estrogen receptor β
AMPK in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.
Management of growth hormone deficiency in adults
Estrogen receptors in health and disease
The role of adipocytes in tissue regeneration and stem cell niches
Sex hormones and immunosenescence
The metabolic basis of pulmonary arterial hypertension
ER Stress is Linked to the Regulation of Hepatic Gluconeogenesis and Phosphatidylinositol 3-kinase/Akt Signaling Post Burn Injury
Therapeutic Options in the Treatment of Diabetes
Eicosanoids in metabolic syndrome
The adrenal steroid status in relation to inflammatory cytokines (interleukin‐6 and tumour necrosis factor) in polymyalgia rheumatica
Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression
The endotoxin-induced increase of cytokines is followed by an increase of cortisol relative to dehydroepiandrosterone (DHEA) in healthy male subjects
Revisiting cAMP signaling in the carotid body
Iminosugar-based inhibitors of glucosylceramide synthase increase brain glycosphingolipids and survival in a mouse model of Sandhoff disease
Alcoholic steatosis in different strains of rat: A comparative study
Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle
Effects of an acute bout of passive hyperthermia therapy on glycemic control and blood pressure response in healthy individuals and type 2 diabetics
Genome-wide interaction-based association analysis identified multiple new susceptibility loci for common diseases
Exercise-induced differential changes in gene expression among arterioles of skeletal muscles of obese rats
The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors
The development of high fat diet induced adiponectin resistance in rodent skeletal muscle
Role of hypoxia-inducible factor 2α in the regulation of adipose tissue inflammation in obesity
Proteomic analysis of hepatitis C virus (HCV) core protein transfection and host regulator PA28γ knockout in HCV pathogenesis: a network-based study
Association between androgenic hormone levels and left ventricular ejection fraction
Could hormones make a difference in the treatment of juvenile rheumatoid arthritis?
In Vivo Role of JAK2 in the Pathogenesis of Obesity and the Metabolic Syndrome
How insulin binds to the insulin receptor
The Regulation of PREX2 by Phosphorylation
Effects on Roux-en-Y gastric bypass in male Wistar rats on fat preference, eating and bone metabolism
9 Mineral Deficiencies
CENTRAL AND PERIPHERAL PEPTIDE REGULATION OF HUNGER, SATIETY AND FOOD
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis
Obesity and Weight Control
Screening candidate longevity therapeutics using gene-expression arrays
Social Isolation Stress, Obesity, and Breast Cancer Risk in Mice
Cross-talk between adipose and gastric leptins for the control of food intake and energy metabolism
Macrophage Polarization And Nitric Oxide Mechanisms In Lymphatic Dysfunction In A Rat Model Of Metabolic Syndrome
In Vivo Radioprotection by 5-Androstenediol: Stimulation of the Innate Immune System
Molecular determinants of the cardiometabolic phenotype
Cardiovascular function in animal models of metabolic syndrome and type 2 diabetes: the role of inducible nitric oxide synthase (iNOS)
Role of the Adipocyte in Development of Type 2 Diabetes
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
Regulation of Metabolic Processes by Micrornas and Class I Histone Deacetylases
Dehydroepiandrosterone in relation to other adrenal hormones during an acute inflammatory stressful disease state compared with chronic inflammatory …
Androstenediol stimulates myelopoiesis and enhances resistance to infection in gamma-irradiated mice
Low serum levels of dehydroepiandrosterone and cortisol in human diffuse cutaneous leishmaniasis by Leishmania mexicana
Mitochondria in cardiac disease
Dehydroepiandrosterone
Replacement therapy with DHEA plus corticosteroids in patients with chronic inflammatory diseases–substitutes of adrenal and sex hormones
Flavonoids: Prospective strategy for the management of diabetes and its associated complications
Radioprotective efficacy and acute toxicity of 5-androstenediol after subcutaneous or oral administration in mice
The Physiology Of Mammalian ER Quality Control: Unfolded Protein Response And ER-Associated Degradation
Positive long-term outcomes from presuckling calcium supplementation in lactating rats and the offspring
Tanshinone IIA pretreatment attenuates hepatic ischemia-reperfusion
Liver monoamine oxidase in lean and obese (ob/ob) mice.
The VEGF receptor family
Iminosugar-based inhibitors of glucosylceramide synthase prolong survival but paradoxically increase brain glucosylceramide levels in Niemann–Pick C mice
Encapsulation of Fish Oil Using Texturized Whey Protein
Long-term effects of growth hormone replacement in hypopituitary adults on body composition, bone mass and cardiovascular risk factors
Cœur et androgenes
Regulation of Metabolism by Hepatic OXPHOS: A Dissertation
Schistosoma japonicum-associated morbidity and its mechanisms among children and young adults in the Philippines
GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function
The Effects of Lipid Availability on Skeletal Muscle Metabolism in Lean and Obese Rodents and Humans
Does supplemental 18: 0 alleviate fish oil-induced milk fat depression in dairy ewes?
Trans-resveratrol induces a potential anti-lipogenic effect in lipopolysaccharide-stimulated enterocytes
Integrative functional genomic analysis unveils the differing dysregulated metabolic processes across hepatocellular carcinoma stages
Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases
Noninsulin-dependent animal models of diabetes mellitus
Interventions in Aging and Age-Related Diseases: The Present and the Future
Studies on the Transcriptional and Enzymatic Control of Steroid Metabolism: Regulation by Lysosomal Acid Lipase, 24-Dehydrocholesterol Reductase, and Amyloid …
A role for the transcriptional repressor ICER in the molecular pathogenesis of type 2 diabetes
The role of stem cells in adipose tissue remodeling.
The role of mammalian target of rapamycin complex 1 in hepatic physiology and disease
Regulation of hepatic ER stress by the E3 ubiquitin ligase gp78 in zebrafish
TOPIC 01–Atherosclerosis, hemostasis, inflammation, AGE–A
Regulation of the memory T cell development and islet beta-cell survival by DAPK-related apoptosis-inducing protein kinase 2 (Drak2)
Inflammatory bowel disease part I: ulcerative colitis–pathophysiology and conventional and alternative treatment options
Acipimox during Short-Term Exercise Exerts A Negative Feedback of Growth Hormone on Ghrelin Secretion in Patients with Bulimia Nervosa and in Healthy Women …
Analysis of immune cell infiltration in white adipose tissue sites before and after bariatric surgery
of environmental substances on bone. More recently, natural diseases such as periodontitis have been studied in nonhuman primates. Experimental model diseases …
Hepatitis C: a retrospective study, literature review, and naturopathic protocol
Neuro-Immune Elements of Inflammatory Disease
Site-directed mutagenesis of the steroid-15beta-hydroxylase (CYP106A2) from Bacillus megaterium ATCC 13368 to alter the regio-selectivity of progesterone …
Challenges in the Management of Acromegaly
The STRIVE-ONR Project: Stress Resistance in Virtual Environments
The Healing Power of Flax: How Nature’s Richest Source of Omega-3 Fatty Acids Can Help to Heal, Prevent and Reverse Arthritis
The role of gut microbiota on obesity development
Eicosanoids in Metabolic Syndrome
Glycosphingolipids in HIV/AIDS: The Potential Therapeutic Application
Ruminant Supplementation of Gluconeogenic Substrates Via Drinking Water
Mechanisms of Methylglyoxal-elicited Leukocyte Recruitment
Regulation of ABCG5 and ABCG8 sterol transporters in biliary cholesterol elimination, reverse cholesterol transport and dyslipidemia
Diseases of the musculoskeletal system
Antifolate modulators of AMP-activated protein kinase signaling as cancer therapeutics
Programming of circadian rhythms in metabolic tissues by fetal glucocorticoid excess and the interactive effects of postnatal dietary fat manipulation
Novel Intrinsic and Extrinsic Approaches to Selectively Regulate Glycosphingolipid Metabolism
Vascular endothelial growth factor D: biology and function in transgenic and knockdown mice
Fibroblast growth factor-21 restores insulin sensitivity but induces aberrant bone microstructure in obese insulin-resistant rats
Activation of Wnt/β‐catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS‐1
Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat
Loss of TAZ Boosts PPARγ to Cope with insulin Resistance
STAT1 dissociates adipose tissue inflammation from insulin sensitivity in obesity
Palmitic acid reduces the autophagic flux and insulin sensitivity through the activation of the free fatty acid receptor 1 (FFAR1) in the hypothalamic neuronal …
4-PBA reverses autophagic dysfunction and improves insulin sensitivity in adipose tissue of obese mice via Akt/mTOR signaling
The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes
Senna alata leaf extract restores insulin sensitivity in high-fat diet-induced obese mice
Iron overload inhibits late stage autophagic flux leading to insulin resistance
Glucocorticoid‐induced insulin resistance in men is associated with suppressed undercarboxylated osteocalcin
Estrogen replacement enhances insulin-induced AS160 activation and improves insulin sensitivity in ovariectomized rats
Adipocyte JAK2 mediates growth hormone–induced hepatic insulin resistance
In vitro treatment of 3 T3-L1 adipocytes with recombinant Calcium/calmodulin-dependent Protein Kinase IV (CaMKIV) limits ER stress and improves insulin …
Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development
Inflammation and insulin resistance: New targets encourage new thinking: Galectin‐3 and LTB4 are pro‐inflammatory molecules that can be targeted to restore …
Chemical inducers of obesity-associated metabolic stress activate inflammation and reduce insulin sensitivity in 3T3-L1 adipocytes
Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle
Carotid body dysfunction in diet-induced insulin resistance is associated with alterations in its morphology
SorCS1 binds the insulin receptor to enhance insulin sensitivity
Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes
Melatonin potentiates the effects of metformin on glucose metabolism and food intake in high‐fat‐fed rats
Effects of growth hormone on hepatic insulin sensitivity and glucose effectiveness in healthy older adults
Increased dynamin‐related protein 1–dependent mitochondrial fission contributes to high‐fat‐diet‐induced cardiac dysfunction and insulin resistance by elevating …
The evaluation of dietary black soybean and purple sweet potato on insulin sensitivity in streptozotocin-induced diabetic rats
N1-Methylnicotinamide Improves Hepatic insulin sensitivity via Activation of SIRT1 and Inhibition of FOXO1 Acetylation
Undercarboxylated Osteocalcin Improves insulin‐Stimulated Glucose Uptake in Muscles of Corticosterone‐Treated Mice
Acyl ghrelin induces insulin resistance independently of GH, cortisol, and free fatty acids
Endoplasmic Reticulum Stress Inhibition by TUDCA Restores insulin Resistance in Patients With Diabetes Mellitus
A severe but reversible reduction in insulin sensitivity is observed in patients with insulinoma
Efficacy of a six-week dispersed Wingate-cycle training protocol on peak aerobic power, leg strength, insulin sensitivity, blood lipids and quality of life in healthy adults
Potential application of testosterone replacement therapy as treatment for obesity and type 2 diabetes in men
Effect of dehydroepiandrosterone (DHEA) on diabetes mellitus and obesity
GLP-1 analogue liraglutide attenuates mutant huntingtin-induced neurotoxicity by restoration of neuronal insulin signaling
Testosterone increases the expression and phosphorylation of AMP kinase α in men with hypogonadism and type 2 diabetes
Pu’erh tea extract-mediated protection against hepatosteatosis and insulin resistance in mice with diet-induced obesity is associated with the induction of de novo …
insulin sensitivity is mediated by glucose in the hepatoportal region in the rat
Interferon beta overexpression attenuates adipose tissue inflammation and high-fat diet-induced obesity and maintains glucose homeostasis
Short-term fasting restores free-choice high-fat, high sugar diet-induced insulin resistance in rats
Mechanisms underlying the metabolic actions of testosterone in humans: A narrative review
insulin signaling in the whole spectrum of GH deficiency
Independent Effect of High Aerobic Capacity To Protect Against Diet-Induced insulin Resistance in Male Rats
The response of insulin signaling proteins IRS1 and PTP-1B to endurance, HIIT and resistance training in rats with experimental diabetes
Infliximab ameliorates tumor necrosis factor‐alpha‐induced insulin resistance by attenuating PTP 1B activation in 3T3L1 adipocytes in vitro
Spinophilin-deficient mice are protected from diet-induced obesity and insulin resistance
SAT-653 Exploring the Role of Brown Adipokines on Hepatic insulin Resistance Using a Microfluidic Organ-On-Chip
Are marine n-3 fatty acids protective towards insulin resistance? From cell to human
Glucoraphanin ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice
Roux-en-Y Gastric Bypass Restores Islet Function and Morphology Independent of Body Weight in ZDF Rats
Bariatric surgery normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice
Reduced oxygen consumption by fat cells improves metabolic defects
Liraglutide ameliorates hyperhomocysteinemia-induced Alzheimer-like pathology and memory deficits in rats via multi-molecular targeting
GM3, Caveolin-1 and insulin Receptor in insulin Resistance
The role of metabolic rate and substrate utilization in the maintenance of body weight, body composition and insulin sensitivity
A novel metformin‐methylglyoxal imidazolinone metabolite (IMZ) sensitizes cells to insulin; a potential role in alleviating T2DM complications
THE EFFECTS OF DEHYDROEPIANDROSTERONE (DHEA) ON DIABETES MELLITUS, OBESITY, AND ATHEROSCLEROSIS
Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet
Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport
Implications of palmitoleic acid (palmitoleate) on glucose homeostasis, insulin resistance and diabetes
Dietary supplementation of vitamin D prevents the development of western diet-induced metabolic, hepatic and cardiovascular abnormalities in rats
Latent inflammation and defect in adipocyte renewal as a mechanism of obesity-associated insulin resistance
2-Methoxyestradiol inhibits high fat diet-induced obesity in rats through modulation of adipose tissue macrophage infiltration and immunophenotype
Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance
Do flavanols-rich natural products relieve obesity-related insulin resistance?
The chemokine CXCL16 can rescue the defects in insulin signaling and insulin sensitivity caused by palmitate in C2C12 myotubes
β-adrenergic receptor and insulin resistance in the heart
BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle
Agmatine ameliorates type 2 diabetes induced-Alzheimer’s disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling
Exercise and metabolic health: beyond skeletal muscle
Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration
Intermittent walking, but not standing, improves postprandial insulin and glucose relative to sustained sitting: a randomised cross-over study in inactive middle-aged …
Amelioration of high-insulin-induced skeletal muscle cell insulin resistance by resveratrol is linked to activation of AMPK and restoration of GLUT4 translocation
Targeting metabolic consequences of insulin resistance in polycystic ovary syndrome by D-chiro-inositol and emerging nutraceuticals: a focused review
insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2× 2 …
Mitochondria-associated membranes (MAMs): a novel therapeutic target for treating metabolic syndrome
Dietary reversal of neuropathy in a murine model of prediabetes and metabolic syndrome
DHA-enriched fish oil reduces insulin resistance in overweight and obese adults
The effect of metaformin treatment on insulin resistance in women with polycystic ovary syndrome
insulin resistance in patients with acromegaly
The effect of handcycle ergometer exercise on glucose tolerance in ambulatory and non-ambulatory adolescents
GPRC6A: Jack of all metabolism (or master of none)
Combined Hyperglycemia- and Hyperinsulinemia-Induced insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ
SUN-094 Long-Term Safety and Efficacy of Leuprorelin in Treating Central Precocious Puberty: A Large, Open-Label, Multicenter, Phase IV Study in China
N-Acetyl-l-Cysteine treatment efficiently prevented pre-diabetes and inflamed-dysmetabolic liver development in hypothalamic obese rats
Inflammation is not a contributing factor in the development of insulin resistance in diet induced obesity in rats
Carnitine palmitoyltransferase 2 knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes
Aging induces an Nlrp3 inflammasome-dependent expansion of adipose B cells that impairs metabolic homeostasis
Androgen profile in young females with insulin resistance; the importance of 17-Hydroxyprogesterone: Androgens in young insulin resistant females
Effects of central FGF21 infusion on the hypothalamus–pituitary–thyroid axis and energy metabolism in rats
Growth factor, energy and nutrient sensing signalling pathways in metabolic ageing
Hepatic insulin clearance: mechanism and physiology
Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis
Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis
DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice
Effect of growth hormone on insulin signaling
Accumulation of intramuscular toxic lipids, a link between fat mass accumulation and sarcopenia
Lycopene Alleviates Obesity‐Induced Inflammation and insulin Resistance by Regulating M1/M2 Status of Macrophages
Metabolic relationship between diabetes and Alzheimer’s disease affected by Cyclo (His-Pro) plus zinc treatment
Growth Hormone and Obesity
Modulation of insulin resistance and the adipocyte-skeletal muscle cell cross-talk by LCn-3PUFA
Fatty Acid Biology and Nutrition to Optimize Health and Production
The effects of growth hormone on adipose tissue: Old observations, new mechanisms
The UPRER: sensor and coordinator of organismal homeostasis
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice
Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients
EFFECT OF BREWED ROBUSTA COFFEE LEAVES ON insulin LEVELS AND HOMA-IR INDEX IN METABOLIC SYNDROME RATS
Inflammation markers in type 2 diabetes and the metabolic syndrome in the pediatric population
FGF21 gene therapy as treatment for obesity and insulin resistance
The role of the novel lipokine palmitoleic acid in health and disease
The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression in human endometrial cells exposed to a PCOS …
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation
Hypothalamic proopiomelanocortin is necessary for normal glucose homeostasis in female mice
The role of dehydroepiandrosterone (DHEA) in skeletal muscle
The therapeutic potential of FGF21 in metabolic diseases: From bench to clinic
Unacylated ghrelin stimulates fatty acid oxidation to protect skeletal muscle against palmitate-induced impairment of insulin action in lean but not high-fat fed …
Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance
In utero low-protein-diet-programmed type 2 diabetes in adult offspring is mediated by sex hormones in rats
Identification of two microRNA nodes as potential cooperative modulators of liver metabolism
Growth hormone acts along the PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes
Plasma irisin modestly increases during moderate and high-intensity afternoon exercise in obese females
Liraglutide alters hepatic metabolism in high-fat fed obese mice: A bioinformatic prediction and functional analysis
A comparative study on the effect of argan oil versus fish oil on risk factors for cardio-vascular disease in high-fat-fed rats
Gestational diabetes mellitus prediction? A unique fatty acid profile study
Pumonary and systemic endothelial function in diabetic animal models: effect of carotid sinus nerve denervation
adiponectin gene therapy for alzheimer disease in a mouse model: abridged secondary
Inflammatory markers in children and adolescents with type 2 diabetes mellitus
SUN-193 A Case of Cushing’s Syndrome Caused by Epidural Corticoidsteroid Injection
“insulin-like” effects of palmitate compromise insulin signalling in hypothalamic neurons
Ileal transposition surgery decreases fat mass and improves glucose metabolism in diabetic GK rats: possible involvement of FGF21
The shutting down of the insulin pathway: a developmental window for Wolbachia load and feminization
Supplementation with Seabuckthorn Oil Augmented in 16:1n–7t Increases Serum Trans-Palmitoleic Acid in Metabolically Healthy Adults: A Randomized Crossover …
Alcohol, adipose tissue and liver disease: mechanistic links and clinical considerations
A porcine placental extract prevents steatohepatitis by suppressing activation of macrophages and stellate cells in mice
Growth hormone controls lipolysis by regulation of FSP27 expression
Circulating micro RNA in insulin resistant horses
Transgenerational supplementation with eicosapentaenoic acid reduced the metabolic consequences on the whole body and skeletal muscle in mice receiving an …
Pathogenesis of Pancreatic Cancer-Related Diabetes Mellitus: Quo Vadis?
Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis
The biology of gangliosides
Adipocytes harbor a glucosylceramide biosynthesis pathway involved in iNKT cell activation
Interrupting prolonged sitting in type 2 diabetes: nocturnal persistence of improved glycaemic control
Regulation of adipose tissue and skeletal muscle substrate metabolism by the stomach-derived hormone, ghrelin
Science behind the cardio-metabolic benefits of omega-3 polyunsaturated fatty acids: biochemical effects vs. clinical outcomes
Dipeptidyl peptidase-4 inhibitor, vildagliptin, improves trabecular bone mineral density and microstructure in obese, insulin-resistant, pre-diabetic rats
Ganglioside GM3 mediates glucose-induced suppression of IGF-1 receptor–Rac1 activation to inhibit keratinocyte motility
Interfering PLD1-PED/PEA15 interaction using self-inhibitory peptides: An in silico study to discover novel therapeutic candidates against type 2 diabetes
Polycystic ovary syndrome: insights into the therapeutic approach with inositols
Effects of exercise intensity on RBP4 levels in female athletes
Omega-3 polyunsaturated fatty acids prevent obesity by improving tricarboxylic acid cycle homeostasis
THERAPY OF ENDOCRINE DISEASE: Growth hormone replacement therapy in adults: 30 years of personal clinical experience
The fatty acid-rich fraction of Eruca sativa (rocket salad) leaf extract exerts antidiabetic effects in cultured skeletal muscle, adipocytes and liver cells
Non-alcoholic fatty liver disease and nutritional implications: special focus on copper
Glucose-sensing transcription factor mondoa/ChREBP as targets for type 2 diabetes: Opportunities and challenges
Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP‐1c suppression
Partial replacement of corn oil with chia oil into a high fat diet produces either beneficial and deleterious effects on metabolic and vascular alterations in rabbits
Ablation of the carotid bodies in disease: meeting its adverse effects
β-Klotho deficiency shifts the gut-liver bile acid axis and induces hepatic alterations in mice
Interleukin-4 improves metabolic abnormalities in leptin-deficient and high-fat diet mice
The effect of metformin treatment on the basal and gonadotropin‐stimulated steroidogenesis in male rats with type 2 diabetes mellitus
Mediators of Metabolism: An Unconventional Role for NOD1 and NOD2
Gene Expression and Clinical Manifestations in Iraqi Patients with Acromegaly
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice
Potential therapeutic targets for atherosclerosis in sphingolipid metabolism
Central Regulation of Metabolism by Growth Hormone
insulin does not rescue cortical and trabecular bone loss in type 2 diabetic Goto-Kakizaki rats
Gene therapy of type 2 diabetes mellitus: state of art
Hypolipidemic and Antioxidant Effects of Citrullus colocynthis Seeds Oil in High-Fat Diets Induced Obese Rats
Docosahexaenoic and eicosapentaenoic fatty acids differentially regulate glucose and fatty acid metabolism in L6 rat skeletal muscle cells
Intergenerational impact of maternal overnutrition and obesity throughout pregnancy in sheep on metabolic syndrome in grandsons and granddaughters
The regulation of lipokines by environmental factors
Thyroid Hormone and Metabolites: Central Versus Peripheral Effects
Effects of periconception cadmium and mercury co-administration to mice on indices of chronic diseases in male offspring at maturity
USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes
Testing the metabolic sink postulate: Subcutaneous adipose tissue the protective depot
The iminosugar AMP-DNM improves satiety and activates brown adipose tissue through GLP1
Hibernation induces widespread transcriptional remodeling in metabolic tissues of the grizzly bear
Graphical abstract Chapter 4: PEDF attenuates insulin-dependent molecular pathways of glucose homeostasis in skeletal myocytes
Endogenous Adipocyte-derived Glucosylce-ramides Drive iNKT Cell Function
Regulation of Postabsorptive and Postprandial Glucose Metabolism by insulin-Dependent and insulin-Independent Mechanisms: An Integrative Approach
Different roles of insulin receptor a and b in maintaining blood glucose homeostasis in zebrafish
The impact of obesity on cardiovascular disease risk factor
Endothelial dysfunction: is there a hyperglycemia-induced imbalance of NOX and NOS?
Monounsaturated Fatty Acids in Obesity-Related Inflammation
Reduced delta-6 desaturase activity partially protects against high-fat diet-induced impairment in whole-body glucose tolerance
Effects of urocortin 2 versus urocortin 3 gene transfer on left ventricular function and glucose disposal
Body Composition Changes with Long-term Pegvisomant Therapy of Acromegaly
Role of Forkhead Box O (FOXO) transcription factor in aging and diseases
Prenatal steroids and metabolic dysfunction: lessons from sheep
Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects: a randomized controlled crossover trial
Therapeutic application of GPR119 ligands in metabolic disorders
Berberine in the treatment of metabolism-related chronic diseases: a drug cloud (dCloud) effect to target multifactorial disorders
Adipose Tissue Composition in Obesity and After Bariatric Surgery
Lower Serum Fibroblast Growth Factor 21 Levels are Associated with Normal Lumbar Spine Bone Mineral Density in Hemodialysis Patients
Identifying New Treatment Options and Risk Factors for Type 2 Diabetes: The Potential Role of Thymoquinone and Persistent Organic Pollutants
Solute excretion, metabolism, and cardio‐renoprotection via two distinct mechanisms revolutionize clinical outcomes
Normal physiology of growth hormone in adults
Endocrine and metabolic disorders in patients with Gaucher disease type 1: a review
Modulation of the carotid body activity to treat obesity
The shutting down of the insulin pathway: a developmental window for Wolbachia load and feminization
“insulin-Like” Effects of Palmitate Might Contribute to the Development of insulin Resistance in Hypothalamic Neurons
PANDORA
Growth hormone upregulates ANGPTL4 mRNA and suppresses lipoprotein lipase via fatty acids: randomized experiments in human individuals
Nutraceuticals and diet in human health and disease. The special issue at a glance
Effects of abomasal infusions of fatty acids and one-carbon donors on hepatic ceramide and phosphatidylcholine in lactating Holstein dairy cows
The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1
Defective adaptive thermogenesis contributes to metabolic syndrome and liver steatosis in obese mice
Pharmacological effects of palmitoylethanolamide on hypertension, insulin-resistance and obesity in murine models
The future of liver transplantation for viral hepatitis
Central Regulation of Metabolism by Growth Hormone. Cells 2021, 10, 129
Glycosphingolipids and infection. Potential new therapeutic avenues
DUSP5 functions as a feedback regulator of TNFα-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes
Alterations of sphingolipid metabolism in different types of polycystic ovary syndrome
Metabolic implications of organelle–mitochondria communication
Could Omega 3 Fatty Acids Preserve Muscle Health in Rheumatoid Arthritis?
Age‐related bone loss is associated with FGF21 but not IGFBP1 in healthy adults
Sphingolipids in adipose tissue: What’s tipping the scale?
Partial remission (honeymoon phase) in type 1 diabetes mellitus
Endothelial dysfunction in obesity
Sirtuins and their biological relevance in aging and age-related diseases
Evidence that a mitochondrial death spiral underlies antagonistic pleiotropy
Therapeutic effects of fibroblast growth factor‑21 against atherosclerosis via the NF‑κB pathway
Regulation of adipose tissue inflammation and systemic metabolism in murine obesity by polymer implants loaded with lentiviral vectors encoding human interleukin …
Neck circumference as an independent predictor for NAFLD among postmenopausal women with normal body mass index
Caloric restriction in heart failure: A systematic review
Omega-3 Polyunsaturated Fatty Acids Mitigate Palmitate-Induced Impairments in Skeletal Muscle Cell Viability and Differentiation
Interactions among mTORC, AMPK, and SIRT: A Computational Model for Cell Energy Balance and Metabolism
Obesity and aging in the Drosophila model
The use of herbal remedies in the treatment of hepatobiliary diseases: trends and prospects
Adipose tissue function and expandability as determinants of lipotoxicity and the metabolic syndrome
Whole egg consumption increases gene expression within the glutathione pathway in the liver of Zucker Diabetic Fatty rats
Flavonoids, dairy foods, and cardiovascular and metabolic health: a review of emerging biologic pathways
Potential molecular mechanism of probiotics in alcoholic liver disease
Evaluation of metabolic changes in liver and serum of streptozotocin-induced diabetic rats after Mango diet supplementation
Extra-Virgin Olive Oil and Type 2 Diabetes Mellitus
Drug treatment strategies for secondary diabetes in patients with acromegaly
Effects of grape pomace and a polyphenolic plant product during the transition period of high-yielding dairy cows: kumulative Dissertation
Fructose Intake: Metabolism and Role in Diseases
Phospholipase D As a Potential Modulator of Metabolic Syndrome: Impact of Functional Foods
Betaine promotes lipid accumulation in adipogenic-differentiated skeletal muscle cells through ERK/PPARγ signalling pathway
Use of Oral Citrulline Administration as a Mitigation Strategy for Fescue Toxicosis in Sheep
Fit with good fat? The role of n-3 polyunsaturated fatty acids on exercise performance
The Roles of CD2AP and SHIP2 in insulin Resistance and Podocyte Apoptosis
Alcohol, adipose tissue and lipid dysregulation
Neuroprotective effects of docosahexaenoic acid against sub-acute manganese intoxication induced dopaminergic and motor disorders in mice
EPA and DHA inhibit myogenesis and downregulate the expression of muscle-related genes in C2C12 Myoblasts
Effects of a dietary supplement enriched in palmitoleic acid on fatty acid composition of follicular fluid, granulosa cell metabolism, and oocyte developmental capacity …
The potential mechanisms of exercise-induced cognitive protection: A literature review.
Derangement of calcium metabolism in diabetes mellitus: negative outcome from the synergy between impaired bone turnover and intestinal calcium absorption
Endoplasmic reticulum stress in metabolic disorders
Fatty acids and NLRP3 inflammasome–mediated inflammation in metabolic tissues
Nutrigenomics of marbling and fatty acid profile in ruminant meat
Induction of stearoyl-CoA 9-desaturase 1 protects human mesenchymal stromal cells against palmitic acid-induced lipotoxicity and inflammation
Gemcitabine potentiates anti-tumor effect of resveratrol on pancreatic cancer via down-regulation of VEGF-B
Health-Promoting Activities of Nigella sativa Fixed Oil
Control of polyunsaturated fatty acids desaturation by Sting regulates inflammatory responses
Bariatric Surgery for Obesity and Metabolic Syndrome
Ethnobotanical description and biological activities of Senna alata
Prognos c value of dehydroepiandrosterone in type 2 diabetes: The Ro erdam Study
Dietary EPA increases rat mortality in diabetes mellitus, a phenomenon which is compensated by green tea extract
Transgenerational effects of periconception heavy metal administration on adipose weight and glucose homeostasis in mice at maturity
Emptying the DUSP Bin: A Role for DUSP5 in Adipose Tissue Inflammation
Emptying Out the DUSP Bin: A Role for DUSP5 in Adipose Tissue Inflammation
Nutritional quality of different grades of adult male chinese mitten crab, Eriocheir sinensis
Cellular responses in rainbow trout (Oncorhynchus mykiss) reared in tritiated water and/or fed organically bound tritium
High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients
Correction of cilia structure and function alleviates multi-organ pathology in Bardet–Biedl syndrome mice
Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice
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