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Rapamycin (Mtor Inhibition)

  1. Mechanism of action of the immunosuppressantย Rapamycin
  2. Rapamycinย in transplantation: a review of the evidence
  3. Rapamycin: Clinical Results and Future Opportunities1
  4. Targets for cell cycle arrest by the immunosuppressantย Rapamycinย in yeast
  5. The target ofย Rapamycinย (TOR) proteins
  6. Solubilization ofย Rapamycin
  7. Rapamune (Sirolimus,ย Rapamycin): an overview and mechanism of action.
  8. Total synthesis ofย Rapamycin
  9. Activity ofย Rapamycinย (AY-22, 989) against transplanted tumors
  10. Rapamycinย suppresses 5โ€ฒTOP mRNA translation throughย inhibitionย of p70s6k
  11. SDZ RAD, a newย Rapamycinย derivative: pharmacological properties in vitro and in vivo
  12. Rapamycin-inducedย inhibitionย of the 70-kilodalton S6 protein kinase
  13. Regulation of cellular growth by the Drosophila target ofย Rapamycinย dTOR
  14. Bench to bedside: the development ofย Rapamycinย and its application to stent restenosis
  15. Rapamycinย (AY-22, 989), a new antifungal antibiotic II. Fermentation, isolation and characterization
  16. Two TOR complexes, only one of which isย Rapamycinย sensitive, have distinct roles in cell growth control
  17. Rapamycinย (AY-22, 989), a new antifungal antibiotic I. Taxonomy of the producing streptomycete and isolation of the active principle
  18. Theย Rapamycin-sensitive signal transduction pathway as a target for cancer therapy
  19. A mammalian protein targeted by G1-arrestingย Rapamycinโ€“receptor complex
  20. Rapamycinย inhibits vascular smooth muscle cell migration.
  21. TOR mutations conferย Rapamycinย resistance by preventing interaction with FKBP12-Rapamycin
  22. Isolation of a protein target of the FKBP12-Rapamycinย complex in mammalian cells
  23. Rapamycinย selectively represses translation of theโ€ polypyrimidine tractโ€ mRNA family
  24. Phosphorylation of the translational repressor PHAS-I by the mammalian target ofย Rapamycin
  25. Rapamycin: distribution, pharmacokinetics and therapeutic range investigations: an update.
  26. Rapamycinย inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
  27. Elucidating TOR signaling andย Rapamycinย action: lessons from Saccharomyces cerevisiae
  28. Biosynthesis of erythromycin andย Rapamycin
  29. Blood distribution ofย Rapamycin.
  30. Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target ofย Rapamycin
  31. Regulation of hypoxia-inducible factor 1ฮฑ expression and function by the mammalian target ofย Rapamycin
  32. Studies on the mechanism of resistance toย Rapamycinย in human cancer cells
  33. Aย Rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
  34. Rapamycin: distribution, pharmacokinetics, and therapeutic range investigations.
  35. Rapamycinย blocks tumor progression: unlinking immunosuppression from antitumor efficacy1
  36. Structure of the FKBP12-Rapamycinย complex interacting with binding domain of human FRAP
  37. Expression and disruption of the Arabidopsis TOR (target ofย Rapamycin) gene
  38. Rapamycinย enhances apoptosis and increases sensitivity to cisplatin in vitro
  39. The biosynthetic gene cluster for the polyketide immunosuppressantย Rapamycin
  40. Mammalian target ofย Rapamycinย (mTOR): pro-and anti-apoptotic
  41. SDZ RAD, a newย Rapamycinย derivative: synergism with cyclosporine
  42. Rapamycinย (AY-22, 989), A NEW ANTIFUNGAL ANTIBIOTIC III. IN VITRO AND IN VIVO EVALUATION
  43. RAFT1: a mammalian protein that binds to FKBP12 in aย Rapamycin-dependent fashion and is homologous to yeast TORs
  44. p53/p21CIP1 cooperate in enforcingย Rapamycin-induced G1 arrest and determine the cellular response toย Rapamycin
  45. Raptor, a binding partner of target ofย Rapamycinย (TOR), mediates TOR action
  46. Rapamycinย selectively inhibits interleukin-2 activation of p70 S6 kinase
  47. The principal target ofย Rapamycinโ€induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.
  48. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
  49. The immunosuppressantย Rapamycinย mimics a starvation-like signal distinct from amino acid and glucose deprivation
  50. Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells
  51. TOR kinase domains are required for two distinct functions, only one of which is inhibited byย Rapamycin
  52. inhibitionย of cell cycle progression byย Rapamycinย induces T cell clonal anergy even in the presence of costimulation
  53. Revised NMR assignments forย Rapamycin
  54. Rapamycinย blocks the phosphorylation of 4Eโ€BP1 and inhibits capโ€dependent initiation of translation.
  55. Absorption and intestinal metabolism of SDZ-RAD andย Rapamycinย in rats
  56. Rapamycinย resistance tied to defective regulation of p27Kip1.
  57. RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/Rapamycinย complex
  58. Targeted disruption of p70s6k defines its role in protein synthesis andย Rapamycinย sensitivity
  59. Target ofย Rapamycinย in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
  60. Rapamycinย prolongs survival and arrests pathophysiologic changes in murine systemic lupus erythematosus
  61. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins
  62. SIROLIMUS (Rapamycin)-BASED THERAPY IN HUMAN RENAL TRANSPLANTATION: Similar Efficacy and Different Toxicity Compared with Cyclosporine: 1, 2
  63. Inhibitors of mammalian target ofย Rapamycinย as novel antitumor agents: from bench to clinic
  64. Cytoplasmicโ€“nuclear shuttling of FKBP12-Rapamycin-associated protein is involved inย Rapamycin-sensitive signaling and translation initiation
  65. A protein kinase B-dependent andย Rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification
  66. Rapamycinย inhibitionย of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability
  67. A chemical genomics approach toward understanding the global functions of the target ofย Rapamycinย protein (TOR)
  68. Mechanism of metabolic control: target ofย Rapamycinย signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors
  69. Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via aย Rapamycin-sensitive pathway
  70. inhibitionย of human B lymphocyte cell cycle progression and differentiation byย Rapamycin
  71. Mammalian target ofย Rapamycinย is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on โ€ฆ
  72. Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 orย Rapamycin.
  73. Cyclosporin A, FK506 andย Rapamycin: more than just immunosuppression
  74. Rapamycinย inhibits human adipocyte differentiation in primary culture
  75. Rapamycinย impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells
  76. inhibitionย of T and B lymphocyte proliferation byย Rapamycin.
  77. Target ofย Rapamycinย (TOR): balancing the opposing forces of protein synthesis and degradation
  78. Partitioning the transcriptional program induced byย Rapamycinย among the effectors of the Tor proteins
  79. Rapamycinย (AY-22, 989), A NEW ANTIFUNGAL ANTIBIOTIC IV. MECHANISM OF ACTION
  80. Control of translation by the target ofย Rapamycinย proteins
  81. Control of Ser2448 phosphorylation in the mammalian target ofย Rapamycinย by insulin and skeletal muscle load
  82. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target ofย Rapamycinย mediated by a protein kinase B signaling pathway
  83. Serumโ€stimulated,ย Rapamycinโ€sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI
  84. Rapamuneยฎ(RAPA,ย Rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction andย inhibitionย of cell cycle โ€ฆ
  85. Regulation of Ribosome Biogenesis by theย Rapamycin-sensitive TOR-signaling Pathway in Saccharomyces cerevisiae
  86. Enhancement of human platelet aggregation and secretion induced byย Rapamycin.
  87. Aย Rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1
  88. Biochemical correlates ofย mTORย inhibitionย by theย Rapamycinย ester CCI-779 and tumor growthย inhibition
  89. The mammalian target ofย Rapamycinย regulates C2C12 myogenesis via a kinase-independent mechanism
  90. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro viaย Rapamycinย (mTOR)โ€dependent signaling
  91. Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites
  92. Immunopurified mammalian target ofย Rapamycinย phosphorylates and activates p70 S6 kinase ฮฑ in vitro
  93. The principalย Rapamycin-sensitive p70 (s6k) phosphorylation sites, T-229 and T-389, are differentially regulated byย Rapamycin-insensitive kinase kinases.
  94. Directย inhibitionย of the signaling functions of the mammalian target ofย Rapamycinย by the phosphoinositide 3โ€kinase inhibitors, wortmannin and LY294002.
  95. Theย Rapamycin-binding domain governs substrate selectivity by the mammalian target ofย Rapamycin
  96. Rapamycinย inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells
  97. Interaction of RAFT1 with gephyrin required forย Rapamycin-sensitive signaling
  98. Rapamycinย causes poorly reversibleย inhibitionย ofย mTORย and induces p53-independent apoptosis in human rhabdomyosarcoma cells
  99. Suppression of B cell activation by cyclosporin A, FK506 andย Rapamycin
  100. Rapamycinย selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins
  101. Rapamycinย and FK506 binding proteins (immunophilins)
  102. Rapamycinย inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis
  103. On the chemistry and high field nuclear magnetic resonance spectroscopy ofย Rapamycin
  104. Solution structure of FKBP, a rotamase enzyme and receptor for FK506 andย Rapamycin
  105. Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506,ย Rapamycinย and cyclosporin A
  106. Activated mammalian target ofย Rapamycinย pathway in the pathogenesis of tuberous sclerosis complex renal tumors
  107. inhibitionย of the mammalian target ofย Rapamycinย sensitizes U87 xenografts to fractionated radiation therapy
  108. Atomic structure of theย Rapamycinย human immunophilin FKBP-12 complex
  109. The FKBP12-Rapamycin-binding domain is required for FKBP12-Rapamycin-associated protein kinase activity and G1 progression
  110. A novel pathway regulating the mammalian target ofย Rapamycinย (mTOR) signaling
  111. Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by theย Rapamycinย targetย mTOR
  112. Mammalian target ofย Rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling
  113. Rapamycin: a bone sparing immunosuppressant?
  114. Insulin-stimulated phosphorylation of lipin mediated by the mammalian target ofย Rapamycin
  115. Mechanism of action ofย Rapamycin: New insights into the regulation of G1-phase progression in eukaryotic cells
  116. Preclinical evaluation of a new potent immunosuppressive agent,ย Rapamycin.
  117. Early clinical experience with a novelย Rapamycinย derivative
  118. Antitumor activity of theย Rapamycinย analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination โ€ฆ
  119. AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target ofย Rapamycinย (mTOR) signaling
  120. Total synthesis ofย Rapamycinย and demethoxyRapamycin
  121. Rapamycinย induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway
  122. Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin andย Rapamycinย in rat adipocytes
  123. Synergistic interactions of cyclosporine andย Rapamycinย to inhibit immune performances of normal human peripheral blood lymphocytes in vitro.
  124. Interaction between FKBP12-Rapamycinย and TOR involves a conserved serine residue.
  125. Comparison of acuteย Rapamycinย nephrotoxicity with cyclosporine and FK506
  126. Refined structure of the FKBP12โ€“Rapamycinโ€“FRB ternary complex at 2.2 ร… resolution
  127. Immunosuppressants FK506 andย Rapamycinย function as reversal agents of the multidrug resistance phenotype
  128. Regulation of the cell integrity pathway byย Rapamycin-sensitive TOR function in budding yeast
  129. Rapamycin, a potent immunosuppressive drug, causes programmed cell death in B lymphoma cells
  130. Sirolimus (Rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease1
  131. Hyperlipidemia in renal transplant recipients treated with sirolimus (Rapamycin)
  132. Effects ofย Rapamycinย on Ryanodine Receptor/Ca2+-Release Channels From Cardiac Muscle
  133. Conversion toย Rapamycinย immunosuppression in renal transplant recipients: report of an initial Experience1
  134. Global and specific translational control byย Rapamycinย in T cells uncovered by microarrays and proteomics
  135. Synergistic effects of cyclosporine andย Rapamycinย in a chronic nephrotoxicity model1
  136. Rapamycinย inhibits constitutive p70s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells
  137. Total synthesis of (-)-Rapamycinย using an Evans-Tishchenko fragment coupling
  138. FKBP12-Rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions
  139. Rapamycinย sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein.
  140. Rapamycinย blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle
  141. FKBP12-Rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction
  142. Modulation of transcription of rRNA genes byย Rapamycin
  143. The effect ofย Rapamycinย on kidney function in the Sprague-Dawley rat.
  144. Organization of the biosynthetic gene cluster forย Rapamycinย in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase
  145. Growth-dependent translation of IGF-II mRNA by aย Rapamycin-sensitive pathway
  146. Effects ofย Rapamycinย in experimental organ allografting.
  147. Metabolic and autocrine regulation of the mammalian target ofย Rapamycinย by pancreatic ฮฒ-cells
  148. Predominant nuclear localization of mammalian target ofย Rapamycinย in normal and malignant cells in culture
  149. Effect of nitrogen source on biosynthesis ofย Rapamycinย by Streptomyces hygroscopicus
  150. Rapamycinโ€sensitive phase of 3T3โ€L1 preadipocyte differentiation after clonal expansion
  151. The mammalian target ofย Rapamycinย phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus
  152. Rapamycinย eluting stent: the onset of a new era in interventional cardiology
  153. Efficacy of sirolimus (Rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: a randomized controlled โ€ฆ
  154. B cell receptor-associated protein ฮฑ4 displaysย Rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A
  155. The immunosuppressantย Rapamycinย induces inactivation of p70s6k through dephosphorylation of a novel set of sites
  156. Regulation of translational effectors by amino acid and mammalian target ofย Rapamycinย signaling pathways: possible involvement of autophagy in cultured โ€ฆ
  157. Molecular mechanisms of immunosuppression by cyclosporine, FK506, andย Rapamycin.
  158. โ€ฆ vascular smooth muscle cell DNA synthesis.ย inhibitionย of basic fibroblast growth factor and platelet-derived growth factor action and antagonism ofย Rapamycinย by โ€ฆ
  159. Mammalian target ofย Rapamycinย pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and โ€ฆ
  160. Influence of cyclosporin, tacrolimus andย Rapamycinย on renal function and arterial hypertension after renal transplantation
  161. Antifungal activities ofย Rapamycinย and its derivatives, prolylRapamycin, 32-desmethylRapamycin, and 32-desmethoxyRapamycin
  162. Rapamycinย inhibits macropinocytosis and mannose receptorโ€“mediated endocytosis by bone marrowโ€“derived dendritic cells
  163. Pharmacokinetics ofย Rapamycin.
  164. The immunosuppressantย Rapamycinย represses human immunodeficiency virus type 1 replication
  165. Treatment withย Rapamycinย and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement.
  166. Rapamycinย inhibits arterial intimal thickening caused by both alloimmune and mechanical injury. Its effect on cellular, growth factor, and cytokine response in injured โ€ฆ
  167. Rapamycinย reverses chronic graft vascular disease in a novel cardiac allograft model
  168. Total synthesis ofย Rapamycinย via a novel titanium-mediated aldol macrocyclization reaction
  169. Cyclosporin A, FK-506, andย Rapamycin: pharmacologic probes of lymphocyte signal transduction
  170. Enhancement of the antifungal activity ofย Rapamycinย by the coproduced elaiophylin and nigericin
  171. โ€ฆ X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 andย Rapamycin
  172. Mammalian target ofย Rapamycin-dependent phosphorylation of PHAS-I in four (S/T) P sites detected by phospho-specific antibodies
  173. Rapamycinย induces apoptosis in monocyte-and CD34-derived dendritic cells but not in monocytes and macrophages
  174. Activation of mRNA translation in rat cardiac myocytes by insulin involves multipleย Rapamycin-sensitive steps
  175. Clinical development of mammalian target ofย Rapamycinย inhibitors
  176. Identification of an 11-kDa FKBP12-Rapamycin-binding domain within the 289-kDa FKBP12-Rapamycin-associated protein and characterization of a critical serine โ€ฆ
  177. COMBINED COSTIMULATION BLOCKADE PLUSย Rapamycinย BUT NOT CYCLOSPORINE PRODUCES PERMANENT ENGRAFTMENT1
  178. Effect of amino acids onย Rapamycinย biosynthesis by Streptomyces hygroscopicus
  179. Rapamycinย antifungal action is mediated via conserved complexes with fkbp12 and tor kinase homologs incryptococcus neoformans
  180. Rapamycin-inducedย inhibitionย of p34cdc2 kinase activation is associated with G1/S-phase growth arrest in T lymphocytes.
  181. Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogateย Rapamycinย cytotoxicity.
  182. โ€ฆ autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target ofย Rapamycin-independent signaling pathway
  183. Control of PHAS-I by insulin in 3T3-L1 adipocytes: synthesis, degradation, and phosphorylation by aย Rapamycin-sensitive and mitogen-activated protein โ€ฆ
  184. Stress-activated protein kinase-2/p38 and aย Rapamycin-sensitive pathway are required for C2C12 myogenesis
  185. Rapamycinย and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependentย inhibitionย of TOR
  186. Rapamycinย (sirolimus, rapamune).
  187. Organisation of the biosynthetic gene cluster forย Rapamycinย in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase
  188. Rapamycinย selectively inhibits angiotensin IIโ€“induced increase in protein synthesis in cardiac myocytes in vitro: potential role of 70-kD S6 kinase in angiotensin II โ€ฆ
  189. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target ofย Rapamycin-dependent signaling pathway
  190. Resistance toย Rapamycin: a novel anticancer drug
  191. Carbon source nutrition ofย Rapamycinย biosynthesis in Streptomyces hygroscopicus
  192. Osteoblastic differentiation is enhanced byย Rapamycinย in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells
  193. Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target ofย Rapamycinย phosphorylation site
  194. Theย Rapamycinย analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats
  195. Regulation of translation elongation factorโ€2 by insulin via aย Rapamycinโ€sensitive signalling pathway.
  196. The FKBP12โ€Rapamycinโ€associated protein (FRAP) is a CLIPโ€170 kinase
  197. Rapamycinย selectively inhibits the growth of childhood rhabdomyosarcoma cells throughย inhibitionย of signaling via the type I insulin-like growth factor receptor
  198. Molecular characterization of a plant FKBP12 that does not mediate action of FK506 andย Rapamycin
  199. Synergistic effect ofย Rapamycinย and cyclosporin A in the treatment of experimental autoimmune uveoretinitis.
  200. Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver
  201. Tuberous sclerosis complex-1 and-2 gene products function together to inhibit mammalian target ofย Rapamycinย (mTOR)-mediated downstream signaling
  202. Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive andย Rapamycin-sensitive PI 3-kinase โ€ฆ
  203. Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation ofย Rapamycinย sensitive signaling
  204. Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporin,ย Rapamycinย and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase โ€ฆ
  205. cAMP-andย Rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells
  206. Aย Rapamycin-selective 25-kDa immunophilin
  207. FKBP12โ€Rapamycinย target TOR2 is a vacuolar protein with an associated phosphatidylinositolโ€4 kinase activity.
  208. Pharmacokinetics and safety of single oral doses of sirolimus (Rapamycin) in healthy male volunteers
  209. Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin andย Rapamycinย in 3T3-L1 adipocytes: evidence for the involvement โ€ฆ
  210. The TOR (target ofย Rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae
  211. Heat capacity changes and hydrophobic interactions in the binding of FK506 andย Rapamycinย to the FK506 binding protein
  212. Attenuation of mammalian target ofย Rapamycinย activity by increased cAMP in 3T3-L1 adipocytes
  213. Rapamycinย specifically interferes with the developmental response of fission yeast to starvation.
  214. CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressantย Rapamycin.
  215. Incorporation of acetate, propionate, and methionine intoย Rapamycinย by Streptomyces hygroscopicus
  216. โ€ฆ Virus 1 Envelope Glycoprotein Complex-induced Apoptosis Involves Mammalian Target ofย Rapamycin/FKBP12-Rapamycinโ€“associated Proteinโ€“mediated p53 โ€ฆ
  217. The efficacy and toxicity ofย Rapamycinย in murine islet transplantation. In vitro and in vivo studies.
  218. Rapamycinย partially prevents insulin resistance induced by chronic insulin treatment
  219. Rapamycinย potentiates transforming growth factor ฮฒ-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells
  220. Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (Rapamycin), mycophenolate mofetil and leflunomide
  221. Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex
  222. Prolongation of renal allograft survival in a large animal model by oralย Rapamycinย monotherapy.
  223. The effect of a highโ€fat meal on the oral bioavailability of the immunosuppressant sirolimus (Rapamycin)
  224. Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target ofย Rapamycin-dependent manner
  225. SIROLIMUS (Rapamycin) HALTS AND REVERSES PROGRESSION OF ALLOGRAFT VASCULAR DISEASE IN NON-HUMAN PRIMATES1
  226. The isolation, synthesis and characterization of an isomeric form ofย Rapamycin
  227. Effects of cyclosporin, FK506, andย Rapamycinย on graft-vessel disease
  228. โ€ฆ translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin: role of mammalian target ofย Rapamycin, protein kinase b, and โ€ฆ
  229. Rapamycinย inhibitionย of interleukin-2-dependent p33cdk2 and p34cdc2 kinase activation in T lymphocytes.
  230. A Unified Total Synthesis of the Immunomodulators (โˆ’)-Rapamycinย and (โˆ’)-27-DemethoxyRapamycin: Assembly of the Common C (1โˆ’ 20) Perimeter and Final โ€ฆ
  231. Mechanism of the combination immunosuppressive effects ofย Rapamycinย with either cyclosporine or tacrolimus
  232. The antimicrobial activities of cyclosporine, FK506, andย Rapamycin
  233. Molecular cloning of a membrane-associated human FK506-andย Rapamycin-binding protein, FKBP-13.
  234. Contrasting impacts of immunosuppressive agents (Rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during โ€ฆ
  235. โ€ฆ new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12: prevention by the immunosuppressant drugs FK506 andย Rapamycin
  236. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 andย Rapamycinย in man and rat.
  237. Rapamycinย Inhibits ฮฑ1-Adrenergic Receptorโ€“Stimulated Cardiac Myocyte Hypertrophy but Not Activation of Hypertrophy-Associated Genes: Evidence for Involvement โ€ฆ
  238. FK506 andย Rapamycin: novel pharmacological probes of the immune response
  239. Target ofย Rapamycin
  240. Mutagenesis of theย Rapamycinย producer Streptomyces hygroscopicus FC904
  241. The effect ofย Rapamycinย on T cell development in mice
  242. The effects ofย Rapamycinย in murine peripheral nerve isografts and allografts
  243. 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance toย Rapamycin
  244. A putative sirolimus (Rapamycin) effector protein
  245. Rapamycin: In Vitro Profile of a New Immunosuppressive Macrolide.
  246. The Upregulation of p27Kip1 byย Rapamycinย Results in G1 Arrest in Exponentially Growing T-Cell Lines
  247. Generation of novelย Rapamycinย structures by microbial manipulations
  248. Consensus guidelines for therapeutic drug monitoring ofย Rapamycin: report of the consensus panel
  249. Comparative study of cyclosporine and tacrolimus vs newer immunosuppressants mycophenolate mofetil andย Rapamycinย on coronary endothelial function
  250. Convergence of the target ofย Rapamycinย and the Snf1 protein kinase pathways in the regulation of the subcellular localization of Msn2, a transcriptional โ€ฆ
  251. FKBP-Rapamycinย inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line.
  252. Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oralย Rapamycin
  253. Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase byย Rapamycin-insensitive pathways in skeletal muscle โ€ฆ
  254. Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, andย Rapamycin
  255. Studies on the chemistry ofย Rapamycin: novel transformations under Lewis-acid catalysis
  256. Rapamycinย on trial
  257. Effects ofย Rapamycinย on cultured hepatocyte proliferation and gene expression
  258. Therapeutic monitoring ofย Rapamycin: a new immunosuppressive drug.
  259. Chlamydia trachomatis Mipโ€like protein has peptidylprolyl cis/trans isomerase activity that is inhibited by FK506 andย Rapamycinย and is implicated in initiation of โ€ฆ
  260. MID1 and MID2 homo-and heterodimerise to tether theย Rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical โ€ฆ
  261. Rapamycinย (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells.
  262. Rapamycinย prevents the onset of insulinโ€dependent diabetes mellitus (IDDM) in NOD mice
  263. Sensitive and specific quantification of sirolimus (Rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry
  264. โ€ฆ LYMPHOCYTES MAY DISTINGUISH CYCLOSPORINE EFFECT IN RENAL TRANSPLANT RECIPIENTS RECEIVING A CYCLOSPORINE+ย Rapamycinย REGIMEN1
  265. Rapamycin, a potential disease-modifying antiarthritic drug.
  266. The insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein 1 phosphorylation bifurcates at aย Rapamycin-sensitive point immediately โ€ฆ
  267. Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target ofย Rapamycin
  268. Treatment of autoimmune uveoretinitis in the rat withย Rapamycin, an inhibitor of lymphocyte growth factor signal transduction
  269. Rapamycin, a potent immunosuppressive drug for vascularized heart, kidney, and small bowel transplantation in the rat.
  270. lnterleukin-2-mediated elimination of the p27 Kipl cyclin-dependent kinase inhibitor prevented byย Rapamycin
  271. Atomic structures of the human immunophilin FKBP-12 complexes with FK506 andย Rapamycin
  272. Ultraviolet-induced phosphorylation of p70S6K at Thr389 and Thr421/Ser424 involves hydrogen peroxide and mammalian target ofย Rapamycinย but not Akt and atypical โ€ฆ
  273. Toxicity ofย Rapamycinโ€“a comparative and combination study with cyclosporine at immunotherapeutic dosage in the rat.
  274. L-Asparaginase inhibits theย Rapamycin-targeted signaling pathway
  275. Theย Rapamycinย and FKBP12 target (RAFT) displays phosphatidylinositol 4-kinase activity
  276. The Target ofย Rapamycinย Signaling Pathway Regulates mRNA Turnover in the Yeast Saccharomyces cerevisiae
  277. Protein kinase activity and identification of a toxic effector domain of the target ofย Rapamycinย TOR proteins in yeast
  278. inhibitionย of in vitro immunoglobulin production byย Rapamycin.
  279. Rapamycinย inhibits corneal allograft rejection and neovascularization
  280. Base catalyzed degradations ofย Rapamycin
  281. Rapamycinย inhibits the generation of graft-versus-host disease-and graft-versus-leukemia-causing T cells by interfering with the production of Th1 or Th1 cytotoxic โ€ฆ
  282. The immunosuppressive macrolides FK-506 andย Rapamycinย act as reciprocal antagonists in murine T cells.
  283. Rapamycin: FK506โ€™s fraternal twin or distant cousin?
  284. Substrate specificity for the human rotamase FKBP: a view of FK506 andย Rapamycinย as leucine-(twisted amide)-proline mimics
  285. Structure-activity studies ofย Rapamycinย analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP โ€ฆ
  286. Rapamycinย reduces hybridoma cell death and enhances monoclonal antibody production
  287. A novel FK506-andย Rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus.
  288. p70s6k integrates phosphatidylinositol 3-kinase andย Rapamycin-regulated signals for E2F regulation in T lymphocytes
  289. DIFFERENTIAL EFFECTS OF CYCLOSPORINE A, METHYLPREDNISOLONE, MYCOPHENOLATE, ANDย Rapamycinย ON CD154 INDUCTION AND REQUIREMENT โ€ฆ
  290. Target ofย Rapamycinย proteins and their kinase activities are required for meiosis
  291. Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line.
  292. inhibitionย byย Rapamycinย of PDGF-and bFGF-induced human tenon fibroblast proliferation in vitro.
  293. New process control strategy used in aย Rapamycinย fermentation
  294. Tacrolimus-Rapamycinย combination therapy for experimental autoimmune uveoretinitis
  295. Serotonin Activates S6 Kinase in aย Rapamycin-Sensitive Manner inAplysia Synaptosomes
  296. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target ofย Rapamycinย in mitogen-stimulated and transformed cells
  297. Insulin regulates lipoprotein lipase activity in rat adipose cells via wortmannin-andย Rapamycin-sensitive pathways
  298. Phosphate, ammonium, magnesium and iron nutrition of Streptomyces hygroscopicus with respect toย Rapamycinย biosynthesis
  299. Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory andย Rapamycinย sensitivity domains.
  300. Growth of Streptomyces hygroscopicus in rotating-wall bioreactor under simulated microgravity inhibitsย Rapamycinย production
  301. Structure ofย Rapamycin: an NMR and molecularโ€dynamics investigation
  302. 40-O-(2-Hydroxyethyl)-Rapamycinย Attenuates Pulmonary Arterial Hypertension and Neointimal Formation in Rats
  303. The Drosophila p70s6k homolog exhibits conserved regulatory elements andย Rapamycinย sensitivity
  304. Structure-activity studies of nonmacrocyclicย Rapamycinย derivatives
  305. Gene disruption and replacement in theย Rapamycin-producing Streptomyces hygroscopicus strain ATCC 29253
  306. Production of synergistic but nonidentical mechanisms of immunosuppression byย Rapamycinย and cyclosporine.
  307. A Unified Total Synthesis of the Immunomodulators (โˆ’)-Rapamycinย and (โˆ’)-27-DemethoxyRapamycin: Construction of the C (21โˆ’ 42) Perimeters
  308. Design and Synthesis of aย Rapamycin-based high affinity binding FKBP12 ligand
  309. Synthetic investigations ofย Rapamycin. 2. Synthesis of a C (22)-C (42) fragment
  310. The immunosuppressantย Rapamycin, alone or with transforming growth factor-b, enhances osteoclast differentiation of RAW264. 7 monocyte-macrophage cells in the โ€ฆ
  311. Origin and true nature of the starter unit for theย Rapamycinย polyketide synthase
  312. โ€ฆ , p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target ofย Rapamycinย (mTOR) pathway in the โ€ฆ
  313. Impaired phosphate handling of renal allografts is aggravated underย Rapamycinโ€based immunosuppression
  314. โ€ฆ in stereochemical communication: a strategy for the stereospecific synthesis and stabilization of the triene substructure ofย Rapamycinย through sulfone substitution
  315. TACROLIMUS (FK506) AND SIROLIMUS (Rapamycin) IN COMBINATION ARE NOT ANTAGONISTIC BUT PRODUCE EXTENDED GRAFT SURVIVAL IN CARDIAC โ€ฆ
  316. Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 andย Rapamycin.
  317. Raf/MAPK andย Rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells
  318. Rapamycinย INDUCES TRANSFORMING GROWTH FACTOR-ฮฒ PRODUCTION BY LYMPHOCYTES1
  319. Insulin release and suppression by tacrolimus,ย Rapamycinย and cyclosporin A are through regulation of the ATPโ€sensitive potassium channel
  320. โ€ฆ kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not byย Rapamycin: evidence that wortmannin โ€ฆ
  321. The Pipecolateโ€Incorporating Enzyme for the Biosynthesis of the Immunosuppressantย Rapamycinโ€”Nucleotide Sequence Analysis, Disruption and Heterologous โ€ฆ
  322. Graft-versus-host disease prevention byย Rapamycin: cellular mechanisms
  323. Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent andย Rapamycinย โ€ฆ
  324. Quantitative analysis of sirolimus (Rapamycin) in blood by high-performance liquid chromatographyโ€“electrospray tandem mass spectrometry
  325. Potentiation of glucocorticoid receptor-mediated gene expression by the immunophilin ligands FK506 andย Rapamycin.
  326. Isolation of two immunosuppressive metabolites after in vitro metabolism ofย Rapamycin.
  327. p-Glycoprotein-mediated transport of a fluorescentย Rapamycinย derivative in renal proximal tubule
  328. Expression, enzyme activity, and subcellular localization of mammalian target ofย Rapamycinย in insulin-responsive cells
  329. Insulin regulation of glucose-6-phosphate dehydrogenase gene expression isย Rapamycin-sensitive and requires phosphatidylinositol 3-kinase
  330. Rapamycinย blocks IL-2-driven T cell cycle progression while preserving T cell survival
  331. Molecular cloning of a 25-kDa high affinityย Rapamycinย binding protein, FKBP25.
  332. The immediate precursor of the nitrogen-containing ring ofย Rapamycinย is free pipecolic acid
  333. Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin)
  334. A novel ring contraction ofย Rapamycin
  335. Prolongation of canine pancreatic islet allograft survival with combinedย Rapamycinย and cyclosporine therapy at low doses.ย Rapamycinย efficacy is blood level related.
  336. inhibitionย of liver, kidney, and intestine regeneration byย Rapamycin
  337. Ig receptor binding protein 1 (ฮฑ4) is associated with aย Rapamycin-sensitive signal transduction in lymphocytes through direct binding to the catalytic subunit of protein โ€ฆ
  338. โ€ฆ of the International Society for Heart and Lung Transplantation working formulation for heart transplant biopsy specimens.ย Rapamycinย Cardiac Rejection Treatment โ€ฆ
  339. Effect ofย Rapamycinย on the cyclosporin Aโ€“resistant CD28-mediated costimulatory pathway
  340. Lack of change of cancellous bone volume with short-term use of the new immunosuppressantย Rapamycinย in rats
  341. Studies towards the total synthesis ofย Rapamycin: A convergent and stereoselective synthesis of the C22๎—ธ C32 carbon framework
  342. Rapamycinย and wortmannin enhance replication of a defective encephalomyocarditis virus
  343. โ€ฆ factor and its transcriptional activator, hypoxia inducible factor-1ฮฑ, through a pathway involving phosphoinositide 3-kinase and the mammalian target ofย Rapamycin
  344. โ€ฆ acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited byย Rapamycin, and is independent โ€ฆ
  345. Effect of p27 deficiency andย Rapamycinย on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model
  346. The effect of dexamethasone, cyclosporine, andย Rapamycinย on T-lymphocyte proliferation in vitro: comparison of cells from patients with glucocorticoid-sensitive and โ€ฆ
  347. Rapamycinย increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect
  348. Complete amino acid sequence of the FK506 andย Rapamycinย binding protein, FKBP, isolated from calf thymus
  349. Effects ofย Rapamycin, cyclosporin A, and dexamethasone on interleukin 5โ€induced eosinophil degranulation and prolonged survival
  350. Microbial conversion ofย Rapamycin
  351. Therapeutic blood levels of sirolimus (Rapamycin) in the allografted rat
  352. Effect ofย Rapamycinย on the expression of the ILโ€2 receptor (CD25)
  353. Rapamycinย inhibits transplant vasculopathy in long-surviving rat heart allografts.
  354. ฮฒ-Agonists regulate Na, K-ATPase via novel MAPK/ERK andย Rapamycin-sensitive pathways
  355. Assessment of cellโ€signaling pathways in the regulation of mammalian target ofย Rapamycinย (mTOR) by amino acids in rat adipocytes
  356. Beneficial effects of cyclosporine andย Rapamycinย in small bowel ischemic injury
  357. Routine clinical monitoring of sirolimus (Rapamycin) whole-blood concentrations by HPLC with ultraviolet detection
  358. inhibitionย byย Rapamycinย of Pโ€glycoprotein 170โ€mediated export from normal lymphocytes
  359. Sample clean-up and high-performance liquid chromatographic techniques for measurement of whole bloodย Rapamycinย concentrations
  360. THE METABOLIC IMPACT OFย Rapamycinย (SIROLIMUS) IN CHRONIC CANINE ISLET GRAFT RECIPIENTS1
  361. Rapamycinย inhibits ribosomal protein synthesis and induces G1 prolongation in mitogen-activated T lymphocytes.
  362. Dominant mutations confer resistance to the immunosuppressant,ย Rapamycin, in variants of a T cell lymphoma
  363. Effects of cyclosporine andย Rapamycinย on immunoglobulin production by preactivated human B cells
  364. Facile synthesis of the โ€œtricarbonylโ€ subunit in the immunosuppressantย Rapamycin
  365. Effects of FK506 andย Rapamycinย on excitationโ€contraction coupling in skeletal muscle fibres of the rat.
  366. Involvement of aย Rapamycin-sensitive pathway in CD40-mediated activation of murine B cells in vitro
  367. Degradation ofย Rapamycin: synthesis of aย Rapamycinย derived fragment containing the tricarbonyl and triene sectors
  368. Calcineurin inhibitorโ€induced chronic nephrotoxicity in liver transplant patients is reversible usingย Rapamycinย as the primary immunosuppressive agent
  369. EFFECT OF TACROLIMUS (FK506) AND SIROLIMUS (Rapamycin) MONO-AND COMBINATION THERAPY IN PROLONGATION OF RENAL ALLOGRAFT โ€ฆ
  370. Efficacy ofย Rapamycinย and FK 506 in prolonging rat hind limb allograft survival.
  371. Distinct repression of translation by wortmannin andย Rapamycin
  372. Evidence thatย Rapamycinย inhibits interleukin-12-induced proliferation of activated T lymphocytes.
  373. Determination ofย Rapamycinย in whole blood by HPLC
  374. Total synthesis ofย Rapamycin
  375. Rapamycinย inhibits p34cdc2 expression and arrests T lymphocyte proliferation at the G1/S transition.
  376. Uncoupling p70s6 kinase activation and proliferation:ย Rapamycin-resistant proliferation of human CD8+ T lymphocytes
  377. Exogenous shikimic acid stimulatesย Rapamycinย biosynthesis inStreptomyces hygroscopicus
  378. Ryanodine receptors from rabbit skeletal muscle are reversibly activated byย Rapamycin
  379. Synthetic studies towardย Rapamycin: a solution to a problem in chirality merger through use of the Ireland reaction
  380. The nature of the starter unit for theย Rapamycinย polyketide synthase
  381. Invasive aspergillosis in mice immunosuppressed with cyclosporin A, tacrolimus (FK506), or sirolimus (Rapamycin)
  382. Proinflammatory effects in experimental mesangial proliferative glomerulonephritis of the immunosuppressive agent SDZ RAD, aย Rapamycinย derivative
  383. USE OF ANTI-CD25 MONOCLONAL ANTIBODY IN COMBINATION WITHย Rapamycinย TO ELIMINATE CYCLOSPORINE TREATMENT DURING THE INDUCTION โ€ฆ
  384. Loss of ypk1 function causesย Rapamycinย sensitivity,ย inhibitionย of translation initiation and synthetic lethality in 14-3-3-deficient yeast
  385. Acute effects ofย Rapamycinย on glomerular dynamics: a micropuncture study in the rat
  386. Cyclosporine, FK506, andย Rapamycin. Some effects on early activation events in serum-free, mitogen-stimulated mouse spleen cells.
  387. The cyclohexane moiety ofย Rapamycinย is derived from shikimic acid in Streptomyces hygroscopicus
  388. Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration ofย Rapamycinย but develop an โ€ฆ
  389. In vitro and in situ absorption of SDZ-RAD using a human intestinal cell line (Caco-2) and a single pass perfusion model in rats: comparison withย Rapamycin
  390. Degradative studies on the tricarbonyl containing macrolideย Rapamycin
  391. The potential role ofย Rapamycinย in pediatric transplantation as observed from adult studies
  392. Comparison of the effects of FK-506, cyclosporin A andย Rapamycinย on IL-2 production.
  393. Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on theย Rapamycin-insensitive site (serine-111)
  394. The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 andย Rapamycin.
  395. Rapamycinย and p53 act on different pathways to induce G1 arrest in mammalian cells
  396. Effect ofย Rapamycinย on rat aortic ring vasomotion.
  397. โ€ฆ cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target ofย Rapamycin
  398. Rapamycinย blocks sexual development in fission yeast throughย inhibitionย of the cellular function of an FKBP12 homolog
  399. Simultaneous on-line extraction and analysis of sirolimus (Rapamycin) and ciclosporin in blood by liquid chromatographyโ€“electrospray mass spectrometry
  400. Bothย Rapamycin-sensitive and-insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat โ€ฆ
  401. Compared to mycophenolate mofetil,ย Rapamycinย induces significant changes on growth factors and growth factor receptors in the early days postkidney โ€ฆ
  402. Mammalian RAFT1 kinase domain providesย Rapamycin-sensitive TOR function in yeast.
  403. Conversion from liquid to solidย Rapamycinย formulations in stable renal allograft transplant recipients
  404. Secretion of FK506/FK520 andย Rapamycinย by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans
  405. Side effects ofย Rapamycinย in the rat
  406. The effect ofย Rapamycinย on single ENaC channel activity and phosphorylation in A6 cells
  407. Rapamycinย (Sirolimus) inhibits vascular smooth muscle DNA synthesis in vitro and suppresses narrowing in arterial allografts and in balloon-injured carotid arteries โ€ฆ
  408. Measurement ofย Rapamycinย in whole blood using reverse-phase high-performance liquid chromatography.
  409. Regulation of theย Rapamycinย and FKBP-target 1/mammalian target ofย Rapamycinย and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase
  410. Rapamycinย stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection.
  411. Two discrete regions of interleukin-2 (IL2) receptor ฮฒ independently mediate IL2 activation of a PD98059/Rapamycin/wortmannin-insensitive Stat5a/b serine โ€ฆ
  412. The tyrosine89 residue of yeast FKBP12 is required forย Rapamycinย binding
  413. Assignment of the human FKBP12-Rapamycin-associated protein (FRAP) gene to chromosome 1p36 by fluorescence in situ hybridization
  414. Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression
  415. Rapamycin: personal algorithms for use based on 250 treated renal allograft recipients.
  416. Rapamycinย INHIBITS DEVELOPMENT OF OBLITERATIVE AIRWAY DISEASE IN A MURINE HETEROTOPIC AIRWAY TRANSPLANT MODEL1
  417. The immunosuppressantย Rapamycinย blocks in vitro responses to hematopoietic cytokines and inhibits recovering but not steady-state hematopoiesis in vivo
  418. Estrogen andย Rapamycinย effects on cell cycle progression in T47D breast cancer cells
  419. The effects of the immunosuppressantย Rapamycinย on the growth of rheumatoid arthritis (RA) synovial fibroblast
  420. Deletion of rapQONML from theย Rapamycinย gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog
  421. Rapamycinย may prevent post-transplant lymphoma
  422. โ€ฆ ฯ€-face selectivity in anti aldol reactions of E-enol borinates from chiral alkoxymethyl ketones: stereocontrolled synthesis of a C24-C32 polyol subunit ofย Rapamycin
  423. โ€ฆ of MAP kinases, pp90rsk and pp70โ€S6 kinases in mouse mast cells by signaling through the cโ€kit receptor tyrosine kinase or FcฯตRI:ย Rapamycinย inhibits activation of โ€ฆ
  424. Intramolecular hydrogen transfer reactions of o-(bromophenyl) dialkylsilyl ethers. Preparation ofย Rapamycin-d1
  425. โ€ฆ 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects ofย Rapamycin, Ly294002, and wortmannin on โ€ฆ
  426. Rapamycinย dissociates p70S6K activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells
  427. Rapamycinย inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells
  428. Rapamycin: immunosuppression, hyporesponsiveness, and side effects in a porcine renal allograft model.
  429. Effect of cyclosporine, mycophenolic acid, andย Rapamycinย on the proliferation of rat aortic vascular smooth muscle cells: in vitro study
  430. Single-channel activity of the Ca2+-dependent K+ channel is modulated by FK506 andย Rapamycin
  431. Use ofย Rapamycinย for the suppression of alloimmune reactions in vivo: schedule dependence, tolerance induction, synergy with cyclosporine and FK 506, and effect on โ€ฆ
  432. Failure ofย Rapamycinย to block proliferation once resting cells have entered the cell cycle despite inactivation of p70 S6 kinase
  433. Rapamycinย inhibits proteasome activator expression and proteasome activity
  434. ASSOCIATION OF GLUCOCORTICOIDS AND CYCLOSPORIN A ORย Rapamycinย PREVENTS E-SELECTIN AND IL-8 EXPRESSION DURING LPS-AND TNFฮฑ โ€ฆ
  435. The zinc finger protein GLI induces cellular sensitivity to theย mTORย inhibitorย Rapamycin
  436. Sirolimus (Rapamycin) in clinical transplantation
  437. Rapamycinย inhibits didemnin Bโ€induced apoptosis in human HLโ€60 cells: Evidence for the possible involvement of FK506โ€binding protein 25
  438. Siloxanes: versatile templates for acyclic stereocontrol. Synthesis of the C27-C33 segment ofย Rapamycin
  439. Dose-dependent pharmacokinetics ofย Rapamycin-28-N,N-dimethylglycinate in the mouse
  440. Interstitial pneumonitis associated with sirolimus (Rapamycin) therapy after liver transplantation
  441. The relationship of blood concentrations ofย Rapamycinย and cyclosporine to suppression of allograft rejection in a rabbit heterotopic heart transplant model.
  442. โ€ฆ -severe combined immunodeficient (HuPBL-SCID) mouse/skin allograft model is T cell mediated and inhibited by a combination of cyclosporine andย Rapamycin
  443. โ€ฆ hydration contributions to the thermodynamics of ligand binding by proteins. Enthalpy and heat capacity changes of tacrolimus andย Rapamycinย binding to FK506 โ€ฆ
  444. Selective epimerization ofย Rapamycinย via a retroaldol/aldol mechanism mediated by titanium tetraisopropoxide
  445. inhibitionย of proliferation but not erythroid differentiation of J2E cells byย Rapamycin
  446. The 14-3-3 proteins positively regulateย Rapamycin-sensitive signaling
  447. Systemic toxicity following administration of sirolimus (formerlyย Rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes
  448. Oral administration ofย Rapamycinย and cyclosporine differentially alter intestinal function in rabbits
  449. p70 S6 kinase sensitivity toย Rapamycinย is eliminated by amino acid substitution of Thr229.
  450. Highโ€Sensitivity sequencing of large proteins: Partial structure of theย Rapamycinโ€fkbp12 target
  451. Renal effects ofย Rapamycinย in the spontaneously hypertensive rat
  452. Effects of immunosuppressants FK506 andย Rapamycinย on the heterooligomeric form of the progesterone receptor
  453. Sirolimus (Rapamycin, Rapamuneยฎ) and combination therapy with cyclosporin A in the rat developing adjuvant arthritis model: correlation with blood levels and the โ€ฆ
  454. The effect ofย Rapamycinย on renal function in the rat: a comparative study with cyclosporine
  455. Efficient Removal of Pipecolinate fromย Rapamycinย and FK506 by Reaction with n-Bu4N+ CNโˆ’
  456. Rapamycinย resistance in ataxia-telangiectasia.
  457. Regulation of ribosomal S6 kinase 2 by mammalian target ofย Rapamycin
  458. Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (Rapamycinย and FK506) and calcium/calmodulin-dependent kinase โ€ฆ
  459. Lipophilic benzamide and anilide derivatives as high-performance liquid chromatography internal standards: application to sirolimus (Rapamycin) determination
  460. Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively withย Rapamycin
  461. โ€ฆ by insulin and insulin-like growth factor-I: glycogen synthase activation is antagonized by wortmannin or LY294002 but not byย Rapamycinย or by inhibiting โ€ฆ
  462. Pharmacokinetics ofย Rapamycin: single-dose studies in the rabbit.
  463. Preferential production ofย Rapamycinย vs prolylRapamycinย by Streptomyces hygroscopicus
  464. Successful myoblast allotransplantation in mdx mice usingย Rapamycin
  465. A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, aย Rapamycin-producing strain
  466. Pediatric utilization ofย Rapamycinย for severe cardiac allograft rejection
  467. An application of the suรกrez reaction to the regiospecific and stereospecific synthesis of the C28-C42 segment ofย Rapamycin
  468. Immunopharmacology ofย Rapamycin
  469. Manipulation of theย Rapamycinย effector domain. selective nucleophilic substitution of the C7 methoxy group
  470. High performance liquid chromatographic isolation, spectroscopic characterization, and immunosuppressive activities of twoย Rapamycinย degradation products
  471. Antifungalย Rapamycinย analogues with reduced immunosuppressive activity
  472. โ€ฆ localization of the human ฮฑ4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of theย Rapamycin-sensitive signal transduction pathway
  473. Antagonistic roles for CTLA-4 and the mammalian target ofย Rapamycinย in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen โ€ฆ
  474. inhibitionย byย Rapamycinย of ornithine decarboxylase and epithelial cell proliferation in intestinal IECโ€6 cells in culture
  475. Insulin stimulation of muscle protein synthesis in obese Zucker rats is not via aย Rapamycin-sensitive pathway
  476. Stability of sirolimus (Rapamycin) in whole blood
  477. Automated simultaneous quantification of the immunosuppressants 40-O-(2-hydroxyethyl)Rapamycinย and cyclosporine in blood with electrospray-mass spectrometric โ€ฆ
  478. Cytokine and alloantibody networks in long term cardiac allografts in rat recipients treated withย Rapamycin.
  479. FK506 andย Rapamycinย modulate the functional activities of human peripheral blood eosinophils
  480. Sirolimus (Rapamycin) potentiates cyclosporine in prevention of acute lung rejection
  481. Rapamycinย potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells
  482. FAP1, a homologue of human transcription factor NFโ€X1, competes withย Rapamycinย for binding to FKBP12 in yeast
  483. Rapamycinย destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3โ€™untranslated region.
  484. Effect ofย Rapamycinย on morphological and functional parameters in the kidney of the rabbit
  485. Synthetic investigations ofย Rapamycin. 1. Synthesis of a C10-C21 fragment
  486. Suppression of acute rejection in allogeneic rat lung transplantation: a study of the efficacy and pharmacokinetics ofย Rapamycinย derivative (SDZ RAD) used alone and โ€ฆ
  487. Proton and nitrogen sequential assignments and secondary structure determination of the human FK506 andย Rapamycinย binding protein
  488. Abrogation byย Rapamycinย of accelerated rejection in sensitized rats byย inhibitionย of alloantibody responses and selective suppression of intragraft mononuclear and โ€ฆ
  489. FK506 binding protein 12 mediates sensitivity to both FK506 andย Rapamycinย in murine mast cells
  490. Post-translational reduction of cell surface expression of insulin receptors by cyclosporin A, FK506 andย Rapamycinย in bovine adrenal chromaffin cells
  491. Antiproliferative effect ofย Rapamycinย on growth factor-stimulated human adult lung fibroblasts in vitro may explain its superior efficacy for prevention and treatment of โ€ฆ
  492. Effects of the combination ofย Rapamycinย with tacrolimus or cyclosporin on experimental intimal hyperplasia
  493. Anisomycin andย Rapamycinย define an area upstream of p70/85S6k containing a bifurcation to histone H3-HMG-like protein phosphorylation and c-fos-c-jun induction.
  494. Rapamycinย inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart โ€ฆ
  495. Studies towards the total synthesis ofย Rapamycin: Preparation of the C10๎—ธ C17 carbon unit
  496. Effects ofย Rapamycinย on apoptosis of rheumatoid synovial cells
  497. Rapamycinย and T cell costimulatory blockade as post-transplant treatment promote fully MHC-mismatched allogeneic bone marrow engraftment under โ€ฆ
  498. Mean field analysis of FKBP12 complexes with FK506 andย Rapamycin: Implications for a role of crystallographic water molecules in molecular recognition and โ€ฆ
  499. Effects of immunosuppressive peptidyl-prolyl cis-trans isomerase (PPIase) inhibitors, cyclosporin A, FK506, ascomycin andย Rapamycin, on hair growth initiation in โ€ฆ
  500. High performance liquid chromatographic isolation and spectroscopic characterization of three major metabolites from the plasma of rats receivingย Rapamycinย โ€ฆ
  501. Implication of alpha4 phosphoprotein and theย Rapamycin-sensitive mammalian target-of-Rapamycinย pathway in prolactin receptor signalling
  502. Effects ofย Rapamycinย on human HLA-unrestricted cell killing
  503. cDNA Cloning of a human 5 kDa FK506 andย Rapamycinย binding protein
  504. Identification of a new metabolite of macrolide immunosuppressant, likeย Rapamycinย and SDZ RAD, using high performance liquid chromatography and electrospray โ€ฆ
  505. Evidence thatย Rapamycinย has differential effects of IL-4 function. Multiple IL-4 signaling pathways and implications for in vivo use.
  506. Calcium/calmodulin kinase inhibitors and immunosuppressant macrolidesย Rapamycinย and FK506 inhibit progestin-and glucocorticosteroid receptor-mediated โ€ฆ
  507. CsA, FK506, corticosteroids andย Rapamycinย inhibit TNFฮฑ production by cultured PTEC
  508. Augmentation of SR Ca2+ release byย Rapamycinย and FK506 causes K+โ€channel activation and membrane hyperpolarization in bladder smooth muscle
  509. Dihydroxylation of the triene subunit ofย Rapamycin
  510. Rituximab andย Rapamycinย for posttransplant lymphoproliferative disease treatment: report of three cases
  511. Effect of single-doseย Rapamycin-based immunosuppression on the development of cardiac allograft vasculopathy.
  512. Rapamycin, FK506 and cyclosporin A inhibit human prolactin gene expression
  513. The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (Rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs โ€ฆ
  514. Rapamycinย selectively blocks interleukin-2-induced proliferating cell nuclear antigen gene expression in T lymphocyte: evidence forย inhibitionย of CREB/ATF โ€ฆ
  515. Rapamycinย treatment depresses intragraft expression of KC/MIP-2, granzyme B, and IFN-gamma in rat recipients of cardiac allografts.
  516. Reversal of ongoing heart, kidney, and pancreas allograft rejection and suppression of accelerated heart allograft rejection in the rat byย Rapamycin.
  517. Glucocorticoid-induced insulin resistance of protein synthesis is independent of theย Rapamycin-sensitive pathways in rat skeletal muscle
  518. Long-term in vivo effects ofย Rapamycinย on humoral and cellular immune responses in the rat
  519. โ€ฆ signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target ofย Rapamycin, and S6 kinases in โ€ฆ
  520. Rapamycin, a potent inhibitor of T-cell function, prevents graft rejection in murine recipients of allogeneic T-cell-depleted donor marrow [published erratum appears in โ€ฆ
  521. Immunosuppressantย Rapamycinย inhibits protein kinase C ฮฑ and p38 mitogen-activated protein kinase leading to theย inhibitionย of chondrogenesis
  522. FK506 andย Rapamycinย selectively enhance degradation of IL-2 and GM-CSF mRNA.
  523. THE IMMUNOSUPPRESSIVE EFFECT OFย Rapamycinย ON MOUSE SMALL BOWEL TRANSPLANTATION1
  524. Studies on selective reductions ofย Rapamycin
  525. Rapamycin: biological and therapeutic effects, binding by immunophilins and molecular targets of action
  526. PHARMACOKINETICS AND TOLERABILITY OF 40โ€“0-[2-HYDROXYETHYL]ย Rapamycinย IN DE NOVO LIVER TRANSPLANT RECIPIENTS1
  527. The synergistic interactions in vitro and in vivo of brequinar sodium with cyclosporine orย Rapamycinย alone and in triple combination.
  528. The future role of target ofย Rapamycinย inhibitors in renal transplantation
  529. Rapamycin-induced long-term allograft survival depends on persistence of alloantigen.
  530. Effects ofย Rapamycinย on renal hemodynamics, water and sodium excretion, and plasma levels of angiotensin II, aldosterone, atrial natriuretic peptide, and vasopressin โ€ฆ
  531. Structural identification of three metabolites and a degradation product of the macrolide immunosuppressant sirolimus (Rapamycin) by electrospray-MS/MS after โ€ฆ
  532. Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressantย Rapamycin.
  533. Comparison of the effect ofย Rapamycinย and FK506 on release of prostacyclin and endothelin in vitro
  534. A nonimmunosuppressive triene-modifiedย Rapamycinย analog is a potent inhibitor of peptidyl prolyl cis-trans-isomerase
  535. Cleavage of the cyclohexyl-subunit ofย Rapamycinย results in loss of immunosuppressive activity
  536. A high performance liquid chromatographic method for the determination ofย Rapamycinย (sirolimus) in rat serum, plasma, and blood and in monkey serum
  537. Cyclosporin A, FK506,ย Rapamycin: the use of a quantitative analytic tool to discriminate immunosuppressive drug interactions.
  538. Quantitative comparison ofย Rapamycinย and cyclosporine effects on cytokine gene expression studied by reverse transcriptase-competitive polymerase chain reaction.
  539. Methionine Interference inย Rapamycinย Production Involves Repression of DemethylRapamycinย Methyltransferase andS-Adenosylmethionine Synthetase
  540. A highly convergent strategy towardsย Rapamycin. Stereoselective construction of the C 8โ€“C 18 fragment
  541. FK506 andย Rapamycinย binding to FKBP: Common elements in immunophilin-ligand complexation
  542. Cloning and sequence analysis of aย Rapamycin-binding protein-encoding gene (RBP1) from Candida albicans
  543. Functional and histopathologic effects ofย Rapamycinย on mouse kidney
  544. Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agentย Rapamycin
  545. Structural basis for peptidomimicry by the effector element ofย Rapamycin
  546. Involvement of theย Rapamycin-sensitive pathway in the insulin regulation of muscle protein synthesis in streptozotocin-diabetic rats
  547. COADMINISTRATION OF NEORAL AND THE NOVELย Rapamycinย ANALOG, SDZ RAD, TO RAT LUNG ALLOGRAFT RECIPIENTS: Potentiation of โ€ฆ
  548. Efficacies of sirolimus (Rapamycin) and cyclosporine in allograft vascular disease in non-human primates: trough levels of sirolimus correlate withย inhibitionย of โ€ฆ
  549. ADJUNCTIVEย Rapamycinย AND CsA TREATMENT INHIBITS MONOCYTE/MACROPHAGE ASSOCIATED CYTOKINES/CHEMOKINES IN SENSITIZED CARDIAC โ€ฆ
  550. Rapamycinย (sirolimus) inhibits heart cell growth in vitro
  551. Rapamycinโ€resistant phosphorylation of the initiation factorโ€4Eโ€binding protein (4Eโ€BP1) in vโ€SRCโ€transformed hamster fibroblasts
  552. Acid catalyzed functionalization ofย Rapamycin
  553. Discordant effects ofย Rapamycinย on proliferation and p70S6 kinase phosphorylation in normal and neoplastic rat chromaffin cells
  554. Missense mutations at the FKBP12-Rapamycin-binding site of TOR1
  555. Nutritional and intestinal effects of the novel immunosuppressive agents: deoxyspergualin,ย Rapamycin, and mycophenolate mofetil
  556. Rapamycinย inhibits protein kinase C activity and stimulates Na+ transport in A6 cells
  557. inhibitionย byย Rapamycinย of leukocyte migration and bronchial hyperreactivity induced by injection of Sephadex beads to guineaโ€pigs
  558. The RB/p107/p130 phosphorylation pathway is not inhibited inย Rapamycin-induced G1-prolongation of NIH3T3 cells.
  559. The mechanism of unresponsiveness to allografts induced byย Rapamycinย andย Rapamycin/cyclosporine treatment in rats.
  560. Calorimetric measurements of the complexation of cyclosporin A, ascomycin, fujimycin, andย Rapamycinย with lithium chloride and with an immunophilin
  561. ANALYSIS OF FUNCTIONAL RENAL ALLOGRAFT TOLERANCE WITH SINGLE-DOSEย Rapamycinย BASED INDUCTION IMMUNOSUPPRESSION1
  562. Genetic relationships among actinomycetes that produce the immunosuppressant macrolides FK506, FK520/FK523 andย Rapamycin
  563. Rapamycinย inhibits IL-1-mediated interferon-gamma production in the YAC-1 T cell lymphoma
  564. Rapamycinย inhibits airway leukocyte infiltration and hyperreactivity in guinea pigs
  565. Synthetic approaches toย Rapamycin
  566. Synthesis of the Tricarbonyl Subunit (C8โˆ’C19) ofย Rapamycinย via Tandem Chan Rearrangementโˆ’Oxidation
  567. Rapamycinย synthetic studies. 2. Elaboration of the C (10)-C (26) perimeter
  568. Use ofย Rapamycinย in a transplant patient who developed cyclosporin neurotoxicity
  569. Prolactin and insulin synergize to regulate the translation modulator PHAS-I via mitogen-activated protein kinase-independent but wortmannin-andย Rapamycinย โ€ฆ
  570. Manipulation of the C (22)-C (27) region ofย Rapamycin: stability issues and biological implications
  571. Opposing effects ofย Rapamycinย and cyclosporin A on activation-induced Ca2+ release
  572. Detection of noncovalent FKBP-FK506 and FKBP-Rapamycinย complexes by capillary electrophoresis-mass spectrometry and capillary electrophoresis-tandem mass โ€ฆ
  573. Comparative effects ofย Rapamycinย FK 506 and cyclosporine on antibody production, lymphocyte populations and immunoglobulin isotype switching in the rat
  574. Rapamycinย insensitivity in Schistosoma mansoni is not due to FKBP12 functionality
  575. Lipase mediated hydrolysis ofย Rapamycinย 42-hemisuccinate benzyl and methyl esters
  576. The effect of the immunophilin ligandsย Rapamycinย and FK506 on proliferation of mast cells and other hematopoietic cell lines.
  577. Rapamycin: A new and highly active immunosuppressive macrolide with an efficacy superior to cyclosporine
  578. Effect of a short course ofย Rapamycin, cyclosporin A, and donor-specific transfusion on rat cardiac allograft survival.
  579. Cyclosporin A, FK506 andย Rapamycinย produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick
  580. Effect ofย Rapamycinย on renal allograft survival in canine recipients treated with antilymphocyte serum, donor bone marrow, and cyclosporine.
  581. Synthesis of Iโ€125 labeled photoaffinityย Rapamycinย analogs
  582. Interleukin 4-inducible phosphorylation of HMG-I (Y) is inhibited byย Rapamycin
  583. inhibitionย of CTL induction byย Rapamycin: IL-2 rescues granzyme B and perforin expression but only partially restores cytotoxic activity.
  584. Effects of cyclosporin A,ย Rapamycin, and FK520 on peripheral T-cell deletion and anergy
  585. The effect of cyclosporin A, FK506 andย Rapamycinย on the murine contact sensitivity reaction
  586. Structure of FKBP12. 6 in complex withย Rapamycin
  587. SUPERIORITY OF SIROLIMUS (Rapamycin) OVER CYCLOSPORINE IN AUGMENTING ALLOGRAFT AND XENOGRAFT SURVIVAL IN MICE TREATED WITH โ€ฆ
  588. Rapamycinย but not FK506 inhibits the proliferation of mononuclear phagocytes induced by colony-stimulating factors
  589. inhibitionย of host-versus-graft and graft-versus-host responses after small bowel transplantation in rats byย Rapamycin.
  590. Rapamycinย and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists.
  591. DETERMINATION OF AN IMPROVED SIROLIMUS (Rapamycin)-BASED REGIMEN FOR INDUCTION OF ALLOGRAFT TOLERANCE IN MICE TREATED WITH โ€ฆ
  592. Structure of the human 25 kDa FK506 binding protein complexed withย Rapamycin
  593. The effects ofย Rapamycinย on humoral immunity in vivo. Suppression of primary responses but not of ongoing alloantibody synthesis or memory responses.
  594. Hypersensitivity toย Rapamycinย of BJAB B lymphoblastoid cells.
  595. โ€ฆ IMMUNOMODULATION LEADS TO ENHANCED ALLOGRAFT SURVIVAL IN COMBINATION WITH CYCLOSPORINE A ANDย Rapamycin, BUT NOT FK5061
  596. The effect ofย Rapamycinย on c-jun expression in human lymphocytes
  597. Tritium labelling of RAD001โ€”a newย Rapamycinย derivative
  598. Relationship between multiple biologic effects ofย Rapamycinย and theย inhibitionย of pp70S6 protein kinase activity. Analysis in mutant clones of a T cell lymphoma.
  599. In vivoย inhibitionย of cytokine responsiveness and graft-versus-host disease mortality byย Rapamycinย leads to a clinical-pathological syndrome discrete from that โ€ฆ
  600. Rapamycinย Prolongs Survival of Murine Recipients of Fully Allogeneic Donor Grafts When Administered during the Graftโ€versusโ€Host Disease Process a
  601. Isolation and identification of newย Rapamycinย dihydrodiol metabolites from dexamethasoneinduced rat liver microsomes
  602. Rapamycinย and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca2+ signaling mechanism in rat hippocampal CA1 neurons
  603. โ€ฆ triamcinolone acetonide accumulation in mouse fibroblasts is differently modulated by the immunosuppressants cyclosporin A, FK506,ย Rapamycinย and their analogues โ€ฆ
  604. โ€ฆ C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target ofย Rapamycinย โ€ฆ
  605. Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target ofย Rapamycin, but independent of โ€ฆ
  606. Conformational changes ofย Rapamycinย and analogs upon complexing with FKBP associated with activity: an application of second derivative CD spectroscopy
  607. inhibitionย of S6 Kinase byย Rapamycinย Blocks Maturation ofRana dybowskiiOocytes
  608. Reversible isomerization ofย Rapamycinย demonstrated by liquid chromatography
  609. The human gene encoding FKBP-Rapamycinย associated protein (FRAP) maps to chromosomal band 1p36. 2
  610. Studies towards the total synthesis ofย Rapamycin: Preparation of the cyclohexyl C33๎—ธ C42 fragment and further coupling to afford the C22๎—ธ C42 carbon unit
  611. The effect of antiโ€ILโ€4 monoclonal antibody,ย Rapamycinย and interferonโ€ฮณ on airway hyperreactivity to acetylcholine in mice
  612. IL-2 induces beta2-integrin adhesion via a wortmannin/LY294002-sensitive,ย Rapamycin-resistant pathway. Phosphorylation of a 125-kilodalton protein correlates with โ€ฆ
  613. Biochemical and structural studies of the FK506-andย Rapamycin-binding proteins (FKBPs).
  614. Rapamycin-sensitive phosphorylation of ribosomal protein S17 by p70 S6 kinase
  615. Differentialย inhibitionย of cutaneous T-cell-mediated reactions and epidermal cell proliferation by cyclosporin A, FK-506, andย Rapamycin
  616. Cyclosporine andย Rapamycinย affect protein kinase C induction of the intracellular activation signal, activator of DNA replication.
  617. The effect of cyclosporin A, FK506, andย Rapamycinย on the murine chronic graftโ€versusโ€host responseโ€”an in vivo model of Th2โ€like activity
  618. Efficacy ofย Rapamycin, RS-61443 and cyclophosphamide in the prolongation of survival of discordant pig to rabbit cardiac xenografts.
  619. Rapamycinย graft pretreatment in small bowel and kidney transplantation in the rat.
  620. Left mainย Rapamycin-coated stent: Invasive versus noninvasive angiographic follow-up
  621. Investigation ofย Rapamycinย transport and uptake across absorptive human intestinal cell monolayers
  622. Effects of wortmannin andย Rapamycinย on CSF-1-mediated responses in macrophages
  623. Cyclosporin A,ย Rapamycinย and FK506 decrease prolactin release from rat pituitary cells in primary culture
  624. Sirolimus: mammalian target ofย Rapamycinย inhibitor to prevent kidney rejection
  625. Hepatotrophic properties in dogs of human FKBP, the binding protein for FK506 andย Rapamycin
  626. Up-regulation of cell surface sodium channels by cyclosporin A, FK506, andย Rapamycinย in adrenal chromaffin cells
  627. Synergistic effect ofย Rapamycinย and cyclosporine in prevention of acute kidney allograft rejection in the mouse
  628. Isolation of a human cDNA encoding a 25 kDa FK-506 andย Rapamycinย binding protein
  629. Suppression of allograft responses by combining alloantigen-specific iv pre-sensitization with suboptimal doses ofย Rapamycin
  630. Rapamycin
  631. Comparison of binding characteristics of fourย Rapamycinย metabolites to the 14 and 52 kDa immunophilins with their pharmacologic activity measured by the mixed โ€ฆ
  632. Hemolytic uremic syndrome after renal transplantation: immunosuppressive therapy withย Rapamycin
  633. Immunosuppressants FK506 andย Rapamycinย have different effects on the biosynthesis of cytoplasmic actin during the early period of T cell activation
  634. Inducible membrane recruitment of small GTP-binding proteins byย Rapamycin-based system in living cells
  635. Intragraft cytokine expressionf in tolerant rat renal allografts withย Rapamycinย and cyclosporin immunosuppression
  636. Evidence thatย Rapamycinย rescue therapy delays rejection of major (MHC) plus minor (non-MHC) histoincompatible heart allografts in rats.
  637. Ethanol potentiates the stimulatory effects of insulin and phosphocholine on mitogenesis by a zinc-dependent andย Rapamycin-sensitive mechanism in fibroblasts and โ€ฆ
  638. โ€ฆ CD8+ T cells tolerized in vivo: employing a model of Ld-specific TCR transgenic mice transplanted with allogenic hearts under the cover of a short-termย Rapamycinย โ€ฆ
  639. Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target ofย Rapamycinย (mTOR) signalling is impaired โ€ฆ
  640. Saccharomyces cerevisiae contains a homolog of human fkbpโ€13, a membraneโ€associated fk506/Rapamycinย binding protein
  641. An unexpected inhibitory effect ofย Rapamycinย against germination of spores of Bacillus brevis strain Nagano
  642. Identification of a 14 kDa FK-506/Rapamycinย binding immunophilin from calf thymus
  643. โ€ฆ โ€“electrospray mass spectrometric assay for the specific and sensitive quantification of the novel immunosuppressive macrolide 40-O-(2-hydroxyethyl)ย Rapamycin
  644. Rapamycinย inhibits activation of ryanodine receptors from skeletal muscle by the fatty acyl CoAโ€“acyl CoA binding protein complex
  645. Exclusion of the 13-kDaย Rapamycinย binding protein gene (FKBP2) as a candidate gene for multiple endocrine neoplasia type 1
  646. Towards the synthesis of the C37-C42 fragment ofย Rapamycin: intramolecular reactions of allyl silanes with oxonium ions generated from ฮฑ-alkoxy sulfones.
  647. Quantitative and temporal analysis of the cellular interaction of FK-506 andย Rapamycinย in T-lymphocytes.
  648. โ€ฆ ARE NOT REQUIRED FOR INDUCTION OF ALLOGRAFT TOLERANCE IN MICE TREATED WITH ANTILYMPHOCYTE SERUM,ย Rapamycin, AND DONOR BONE โ€ฆ
  649. A comparison of the effects ofย Rapamycinย and cyclosporine on kidney and heart morphology in a rabbit heterotopic heart transplant model
  650. Murine TRAIL (TNF-related apoptosis inducing ligand) expression induced by T cell activation is blocked byย Rapamycin, cyclosporin A, and inhibitors of โ€ฆ
  651. Cyclosporine, FK-506,ย Rapamycin, and other immunomodulators
  652. Rapamycinย INDUCES TGF-ฮฒ PRODUCTION IN LYMPOCYTES
  653. Marked prolongation of rat skin xenografts induced by intrathymic injection of xenogeneic splenocytes and a short course ofย Rapamycinย in antilymphocyte serum โ€ฆ
  654. inhibitionย of cellular transfer of experimental autoimmune uveoretinitis byย Rapamycin
  655. Rapamycin: a future in cancer treatment?
  656. Reduction of Sephadex-induced lung inflammation and bronchial hyperreactivity byย Rapamycin.
  657. K+ currents responsible for repolarization in mouse ventricle and their modulation by FK-506 andย Rapamycin
  658. 14-3-3ฯ„ associates with a translational control factor FKBP12-Rapamycin-associated protein in T-cells after stimulation by pervanadate
  659. IL-2-dependent induction of G1 cyclins in primary T cells is not blocked byย Rapamycinย or cyclosporin A
  660. Evidence that FK506 andย Rapamycinย block T cell activation at different sites relative to early reversible phosphorylation involving the protein phosphatases PP1 and โ€ฆ
  661. Partial characterization of a 52 kDa CsA/FK506/Rapamycinย binding protein
  662. Rapamycin: Therapeutic range investigations
  663. Brief treatment withย Rapamycinย in vivo increases responsiveness to alloantigens measured by the mixed lymphocyte response
  664. Anti-CD2 monoclonal antibodies synergize with FK506 but not with cyclosporine orย Rapamycinย to induce tolerance.
  665. Up-regulation of insulin-like growth factor binding protein-5 is independent of muscle cell differentiation, sensitive toย Rapamycin, but insensitive to wortmannin and โ€ฆ
  666. The effect of cyclosporine,ย Rapamycinย and FK 506 the survival following allogeneic bone marrow transplantation
  667. Treatment of normal skeletal muscle with FK506 orย Rapamycinย results in halothane-induced muscle contracture
  668. EFFECT OF IN VIVOย Rapamycinย TREATMENT ON DE NOVO T-CELL DEVELOPMENT IN RELATION TO INDUCTION OF AUTOIMMUNE-LIKE โ€ฆ
  669. Swinging the vote forย Rapamycin
  670. Activation of 70โ€kDa S6 kinase, induced by the cytokines interleukinโ€3 and erythropoietin and inhibited byย Rapamycin, is not an absolute requirement for cell โ€ฆ
  671. Rapamycinย increases transforming growth factor-ฮฒ mRNA expression in immortalized rat proximal renal tubular cells
  672. Divergent effects ofย Rapamycinย on mouse and rat cells following mitogenic stimulation
  673. Differential effects of the immunosuppressive macrolides FK-506 andย Rapamycinย on activation-induced T-cell apoptosis
  674. Induction of tolerance to skin allografts by intrathymic injection of donor splenocytes. Effect of donor-recipient strain combination and supplementalย Rapamycin.
  675. Isolation and identification of a C39 demethylated metabolite ofย Rapamycinย from pig liver microsomes and evaluation of its immunosuppressive activity
  676. โ€ฆ from pig liver microsomes, identification by electrospray tandem mass spectrometry and in vitro immunosuppressive activity of aย Rapamycinย trisโ€epoxide metabolite
  677. Ionization of the c7 methoxy group inย Rapamycinย by 5 M lithium perchlorate-diethyl ether
  678. Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 andย Rapamycin
  679. Mammalian target ofย Rapamycin: Immunosuppressive drugs offer new insights into cell growth regulation
  680. Rapamycin-induced apoptosis is p53-independent in human prostate carcinoma PC-3 cells
  681. Probing T-cell signal transduction pathways with the immunosuppressive drugs, FK-506 andย Rapamycin
  682. Stereoselective construction of the C 21โ€“C 42 fragment ofย Rapamycin
  683. Rapamycinย FOR REFRACTORY RENAL ALLOGRAFT REJECTION.
  684. Cโ€14 labelling of NVP RAD001โ€”a newย Rapamycinย derivative
  685. The immunosuppressive macrolides FK-506 andย Rapamycin
  686. Inhibitors of mammalian target ofย Rapamycin
  687. inhibitionย of the Mr 70,000 S6 kinase pathway byย Rapamycinย results in chromosome malsegregation in yeast and mammalian cells
  688. Possible involvement ofย Rapamycin-sensitive pathway in Bcl-2 expression in human neuroblastoma SH-SY5Y cells
  689. Ionizing radiation enhances double-strand-break repair inย Rapamycin-treated ataxia telangiectasia lymphoblasts
  690. Effect ofย Rapamycinย on prolactin-stimulated S6 kinase activity and milk product formation in mouse mammary explants
  691. Differential effect ofย Rapamycinย and cyclosporin A in proliferation in a murine T cell line expressing either intermediate or high affinity receptor for IL-2
  692. A short-term combination therapy with cyclosporine andย Rapamycinย or leflunomide induces long-term heart allograft survival in a strongly immunogenic strain โ€ฆ
  693. FK-506 andย Rapamycinย but not cyclosporin inhibit aldosterone-stimulated sodium transport in A6 cells
  694. FK506 andย Rapamycin: Differential sensitivity of human, baboon, cynomolgus monkey, dog and pig lymphocytes
  695. Late adjunctive therapy with single doses ofย Rapamycinย in skin-allografted mice treated with antilymphocyte serum and donor bone marrow cells
  696. Rapamycinย inhibits substance P-induced protein synthesis and phosphorylation of PHAS-I (4E-BP1) and p70 S6 kinase (p70 (S6K)) in human astrocytoma cells
  697. โ€ฆ peptide corresponding to residues 65โ€“79 of an HLA class II sequence: functional similarities but mechanistic differences with the immunosuppressive drugย Rapamycin
  698. Synthesis and bioactivity of photolabile sirolimus (Rapamycin) analogs
  699. Rapamycinย for GVHD prophylaxis-potential for severe myelotoxicity
  700. Provocative effects of the immunosuppressantsย Rapamycin, tacrolimus, and dexamethasone on Pneumocystis carinii pneumonitis in contrast to the anti-Pneumocystis โ€ฆ
  701. Comparative effects of FK-506,ย Rapamycinย and cyclosporin A, on the in vitro differentiation of dorsal root ganglia explants and septal cholinergic neurons
  702. Antiโ€CD28 antibodyโ€and ILโ€4โ€induced human T cell proliferation is sensitive toย Rapamycin
  703. Rapamycinย inhibits aldolase A expression during human lymphocyte activation
  704. The effects of FK 506, cyclosporine, andย Rapamycinย on liver growth in vitro and in vivo
  705. Analogous conformations of both binding and effector regions in cyclosporin A, FK506 andย Rapamycin
  706. X-ray Crystal Structure of 28-O-MethylRapamycinย complexed with FKBP12:โ€‰ Is the Cyclohexyl Moiety Part of the Effector Domain ofย Rapamycin?
  707. Rapamycin, cyclosporine, and perioperative donor-specific transfusions induce prolongation of cardiac allograft survival in the rat.
  708. Structure-activity relationships involving modifications to the macrolides FK-506 andย Rapamycin
  709. Comparative study of CSA and FK506 versus newer immunosuppressive drugs MMF andย Rapamycinย on coronary endothelial function in vitro
  710. PHAS-I phosphorylation in response to foetal bovine serum (FBS) is regulated by an ERK1/ERK2-independent andย Rapamycin-sensitive pathway in 3T3-L1 โ€ฆ
  711. Structural analysis ofย Rapamycinย and related compounds using [M + Li]+ ions generated by liquid secondary ion mass spectrometry
  712. The gene structure and promoter analysis of mouse lymphocyte signal transduction molecule ฮฑ4 that is related to the yeast TAP42 involved in aย Rapamycin-sensitive โ€ฆ
  713. The transcriptional profile of Saccharomyces cerevisiae exposed toย Rapamycinย mimics the profile induced by amino acid starvation
  714. โ€ฆ with chiral homoallylic ethers: An application to the asymmetric synthesis od (11R, 14S)-anti-and (31R, 34S)-syn-segements of immunosuppressantย Rapamycin
  715. SAFETY AND PHARMACOKINETIC PROFILE OF ASCENDING SINGLE DOSES OF ORAL LIQUID SIROLIMUS (Rapamycin) IN PEDIATRIC PATIENTS WITH STABLE โ€ฆ
  716. โ€ฆ suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and aย Rapamycinย derivative, SDZ-RAD
  717. โ€ฆ factor ฮฒ1 inhibits interleukinโ€1โ€induced but enhances ionomycinโ€induced interferonโ€ฮณ production in at cell lymphoma: Comparison with the effects ofย Rapamycin
  718. Long-term viability of articular cartilage after microsurgical whole-joint transplantation and immunosuppression withย Rapamycin, mycophenolate mofetil, and tacrolimus
  719. Effect of cyclosporin A,ย Rapamycin, and FK-506 on corneal epithelial cells and lymphocyte proliferation
  720. Comparative in vitro studies on the immunosuppressive activities of mycophenolic acid, bredinin, FK 506, cyclosporine, andย Rapamycin
  721. Responsiveness of preactivated B cells to IL-2 and IL-6. Effect of cyclosporine andย Rapamycin.
  722. Differential effects of cyclosporin-A andย Rapamycinย on in vivo thymocyte maturation
  723. Immunopharmacology ofย Rapamycinย (A review)
  724. Synergism between corticosteroids andย Rapamycinย for the treatment of intraocular inflammation
  725. Rapamycinย induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats
  726. Intrasplenic liver parenchymal cells in conjunction with low-doseย Rapamycinย and cyclosporine induce a unique and specific prolongation of rat cardiac and small bowel โ€ฆ
  727. Target ofย Rapamycinย (TOR) signaling coordinates tRNA and 5S rRNA gene transcription with growth rate in yeast
  728. HPLC Analysis ofย Rapamycin
  729. TGF-beta Provides the Rationale for the Synergistic Immunpsuppression withย Rapamycinย (RAPA), Cyclosporine (CsA) and Tacrolimus (TAC)
  730. Pharmacokinetic and pharmacodynamic correlations of cyclosporine (CsA) andย Rapamycinย (RAPA) in 120 patients treated for at least 2 years at a single center.
  731. Effects of mycophenolic acid,ย Rapamycin, and carvedilol on the PDGF-induced fibronectin secretion by rat vascular smooth muscle cells: Implication of MAP kinase
  732. The Effect of Immunosuppressive Agents (FKโ€506,ย Rapamycin) on Renal P450 Systems in Rat Models
  733. A comparison of in vivo responses to cyclosporine, FK506, andย Rapamycinย following allogeneic immune challenge
  734. Rapamycinย inhibits the in vitro release of soluble CD23 by SAC/IL-2/IL-4-activated human peripheral blood B lymphocytes
  735. Comparison of FKโ€506,ย Rapamycin, Ascomycin, and Cyclosporine in Mouse Models of Hostโ€versusโ€Graft Disease and Heterotopic Heart Transplantation
  736. Generation and evaluation of putative neuroregenerative drugs: Part 2: Screening virtual libraries of novel polyketides which possess the binding domain ofย Rapamycin
  737. Steroids,ย Rapamycin, and breast cancer cells.
  738. ADDITION OFย Rapamycinย TO CYCLOSPORINE-PREDNISONE BASED IMMUNOSUPPRESSION REDUCES THE CLINICAL RISK OF PRETRANSPLANT ANTI โ€ฆ
  739. Rapamycinย treatment depresses
  740. Osmotic pump delivery ofย Rapamycin
  741. An open-label multi-center clinical study of the efficacy and safety ofย Rapamycinย in combination with CsA and steroid to prevent the acute rejection of kidney โ€ฆ
  742. inhibitionย of anti-CD3 antibody-induced mouse T cell activation by pentoxifylline in combination withย Rapamycinย or A77 1726 (leflunomide)
  743. Prevention of cardiac allograft rejection by FK506 andย Rapamycin: assessment by histology and nuclear magnetic resonance
  744. Induction of IL-5 expression by IL-2 is resistant to the immunosuppressive agents cyclosporin A andย Rapamycin.
  745. Rapamycinย inhibits the in vitro release of soluble interleukin-2 receptor by activated peripheral blood mononuclear cells (PBMC) independently of the mode of โ€ฆ
  746. Rapamycinย (Sirolimus) reduces luminal narrowing after balloon angioplasty in porcine coronary arteries
  747. Theย Rapamycinย sensitivity of human T-cell leukaemia virus type I-induced T-cell proliferation is mediated independently of the polypyrimidine motifs in the 5โ€ฒ long โ€ฆ
  748. Signaling Pathways for Translation: Stress, Calcium, andย Rapamycin
  749. Rapamycinย and reduced dose cyclosporin produce effective immunosuppression for de novo renal transplant recipients
  750. Differentiation byย Rapamycin
  751. Generation and evaluation of putative neuroregenerative drugs: Part 1: virtual point mutations to the polyketideย Rapamycin
  752. Triglyceride (TG) elevations in renal transplant recipients treated with sirolimus (Rapamycin, RAPA) added to a cyclosporine (CsA)/prednisone (pred) regimen
  753. Rapamycin: a new immunosuppressive agent capable of inhibiting chronic rejection?
  754. Effects ofย Rapamycinย and FK 506 on Rat Sertoli Cells In Vitro
  755. The Immunosuppressantย Rapamycinย Induces Inactivation
  756. Effect of immunosuppressants FK506 andย Rapamycinย on the function of progesterone receptor: proteinโ€ p59-HBIโ€, intersection between immunology and endocrinology โ€ฆ
  757. Effects ofย Rapamycinย on the proliferation and the prodution of IL-2, IFN-ฮณ, TNF-ฮฑ of spleniclymphocytes in mice [J]
  758. Rapamycin-inducible Secretion of a Therapeutic Protein in the Eye After Transduction With Viral Vectors
  759. High performance liquid chromatographic isolation and spectroscopic characterization of metabolites from the bile of rats receivingย Rapamycinย (sirolimus) โ€ฆ
  760. In vitro IgE production by interleukin 4-stimulated human peripheral blood mononuclear cells is suppressed byย Rapamycin
  761. Conformational sensitivity analysis of FKBPโ€“FK506/Rapamycinย complexes
  762. Rapamycinย (sirolimus, RapamuneTM): A novel immunosuppressive agent
  763. Cytokine expression in a stringent, single-doseย Rapamycin, renal allograft model
  764. Induction ofย Rapamycinย sensitivity by the Gli oncogene.
  765. Conversion from cyclosporine toย Rapamycinย in renal transplant recipients-Report of an initial experience.
  766. IL-2 DEPENDENTย Rapamycinย RESISTENT SIGNALS ARE REQUIRED FOR TOLERANCE INDUCTION AND T CELL APOPTOSIS
  767. Supercritical fluid chromatography for therapeutic drug monitoring of immunosuppressants: selectivity for cyclosporine A, FK 506 (tacrolimus), andย Rapamycin
  768. Total syntheses ofย Rapamycinย and 32-(S)-dihydroRapamycin.
  769. Rapamycinย does not improve renal function or reduce profibrotic gene expression in chronic allograft nephropathy
  770. THEย Rapamycinย ANALOGUE SDZ RAD INHIBITS LPS AND ANTI-CD3mAb INDUCED IL-10 SYNTHESIS IN VITRO AND IN HUMAN RENAL ALLOGRAFT โ€ฆ
  771. Studies directed towards the synthesis ofย Rapamycin
  772. Choosing rational combinations of therapeutic agents: Contrasting effects of costimulation blockade plusย Rapamycinย or cyclosporin on intragraft expression of โ€ฆ
  773. Effects of FK506 andย Rapamycinย on formation of the neural tube in chick embryos
  774. Increased LFA-1-mediated homotypic cell adhesion is associated with the G1 growth arrest induced byย Rapamycinย in a T cell lymphoma
  775. The biosynthesis ofย Rapamycin
  776. Studies towards the total synthesis ofย Rapamycin
  777. FOUR-YEAR CONTROL OF A CLINICALย Rapamycinย ASSAY
  778. Control of translation by a novel,ย Rapamycin-sensitive signaling pathway.
  779. The total synthesis of (-)-Rapamycin
  780. Total synthesis ofย Rapamycin.
  781. Rapamycinย inhibits HMGB1 expression and releases in RAW264. 7 cells induced by lipopolysaccharides in vitro
  782. Effects ofย Rapamycinย and insulin on the cell cycle and apoptosis of hybridoma cell cultures
  783. Rapamycinย inhibits proliferating cell nuclear antigen expression and arrests keratinocytes in the G 1 phase of the cell cycle in vitro.
  784. The Immunophilin Ligandย Rapamycin: A Probe for the Analysis of the Relationship of Apoptosis to the Cell Cycle
  785. Comparison between effects of mycophenolate mofetil andย Rapamycinย on proliferation and apoptosis of cyst-lining epithelial cells of ADPKD patients
  786. Synthetic methods directed towards the synthesis ofย Rapamycin.
  787. โ€ฆ ALLOGRAFT NEPHROPATHY: A PROSPECTIVE RANDOMISED TRIAL OF CYCLOSPORIN REDUCTION WITH OR WITHOUTย Rapamycin.: Abstract# 432 Poster โ€ฆ
  788. Methionine Interference inย Rapamycin
  789. Evaluation of the Influence of FK 506,ย Rapamycin, and Cyclosporine on Processing and Presentation of Particulate Antigen by Macrophages: Assessment of a โ€ฆ
  790. Sirolimus (Rapamycin) monotherapy prevents graft vascular disease in non-human primates
  791. Use of anti-CD25 monoclonal antibody in combination withย Rapamycinย to reduce or eliminate cyclosporine treatment during the induction phase of โ€ฆ
  792. Efficacy of 40-O-(2-hydroxyethyl)-Rapamycinย in preventing chronic renal allograft rejection in rats
  793. Effect of cyclosporin A, FK506 andย Rapamycinย on proliferation and soluble IL-2 receptor release from mitogenically stimulated rat spleen cells
  794. Coadministered neoral and the newย Rapamycinย derivative, SDZ RAD, for nonhuman primate lung transplantation: systematic pharmcokinetic-based trials to maximize โ€ฆ
  795. Effects ofย Rapamycinย on number and activity of endothelial progenitor cells
  796. Total Synthesis ofย Rapamycin
  797. Rapamycinย has no effect on established allograft vasculopathy
  798. Total Synthesis ofย Rapamycin
  799. Therapeutic monitoring of cyclosporine, FK-506, andย Rapamycin
  800. Insensitivity towardsย inhibitionย by cyclosporin A,ย Rapamycinย and tacrolimus in human intestinal lamina propria T lymphocytes
  801. Cyclosporine but notย Rapamycinย stimulates endothelin-1 secretion by endothelial cells: Potential significance in transplant vasculopathy
  802. Rapamycinย RESCUE IN PEDIATRIC LIVER RECIPIENTS WITH TACROLIMUS TOXICITY. A PRELIMINARY EFFECT: CONCENTRATION ANALYSIS.: Abstract# 210 โ€ฆ
  803. Studies towards the total synthesis ofย Rapamycin
  804. Inhibitory Effects ofย Rapamycinย on the Experimental Allograft Rejection
  805. Innovative technique for immunosuppresion involving administration ofย Rapamycinย loaded formed blood elements
  806. Regulation and identification ofย Rapamycinย sensitive phosphorylation sites of p70s6k
  807. Studies directed toward the synthesis of the southern fragment ofย Rapamycin
  808. Inhibitors of Mammalian Target ofย Rapamycin
  809. Effect ofย Rapamycinย on allograft rejection and immune response in mice
  810. In vitro and in vivo assessment ofย Rapamycinย as an immunosuppressive agent in the rabbit
  811. Synthetic studies on the C10-C17 fragment ofย Rapamycin
  812. Effects ofย Rapamycinย on the proliferation and the prodution of IL-2, IFN-?, TNF-? of spleniclymphocytes in mice
  813. Synergism between corticosteroids andย Rapamycinย for the treatment of intraocular inflammation
  814. Rapamycinย and C (27)-demethoxyRapamycin: An efficient stereocontrolled synthesis of the C (1)-C (20) and C (22)-C (26) fragments.
  815. The effect ofย Rapamycinย in prologation of adrenal allograft survival in the rat
  816. inhibitionย of cellular transfer of experimental autoimmune uveoretinitis byย Rapamycin
  817. Rapamycinย and other natural products affect regulation of the growth and differentiation of Saccharomyces cerevisiae.
  818. Biosynthesis ofย Rapamycinย by streptomyces hygroscopicus
  819. Rapamycin, FRAP and the Control of 5โ€™TOP mRNA Translation
  820. Synergistic effects of mycophenolate mofetil (MMF) and sirolimus (Rapamycin, RAPA) in prevention of acute heart, pancreas and kidney allograft rejection and in โ€ฆ
  821. Therapeutic window of whole bloodย Rapamycinย concentration in recipients of renal transplantation
  822. Syntheses and biological activities of natural products:ย Rapamycin, balanol and the maduropeptin chromophore.
  823. The immunosuppressive effect ofย Rapamycinย on lymphocytic proliferation and DTH, GVHR
  824. Risk factors forย Rapamycin-induced thrombocytopenia and leukopenia in renal transplant recipients
  825. Immunosuppressive effect ofย Rapamycinย on heart allotransplantation in the rat [J]
  826. The effect of soy protein on serum lipids in kidney transplant patients receivingย Rapamycin.
  827. Aberrant expression of mammalian target ofย Rapamycinย in stage โ…ขB colon cancer and its significance
  828. Rapamycinย Inhibits 3T3-L1 Adipocyte Differentiation Independent of Clonal Expansion
  829. Effect ofย Rapamycinย on the cyclosporin A-resistant CD28-mediated
  830. Synthetic approaches to the tricarbonyl subunit ofย Rapamycin
  831. Molecular mechanisms of action of the immunosuppressive drugs cyclosporin A, FK506 andย Rapamycin.
  832. Effects ofย Rapamycinย on chronic nephrotoxicity induced by cyclosporine A in rats
  833. Rapamycinย antagonizes interleukin-6 mediated growth arrest and differentiation of myeloblastic M1 cells
  834. Cyclin D3, a key cyclin in human lymphocyte proliferation andย Rapamycin-mediated immunosuppression.
  835. EXTREME HYPERLIPIDEMIA RESULTING FROMย Rapamycin-DERIVED DRUG ADMINISTRATION.: Abstract# 827 Poster Board#-Session: P84-III
  836. Siloxanes as templates in asymmetric synthesis: Studies directed towards the synthesis ofย Rapamycin.
  837. FK 506 versus cyclosponne a for steroid-free synergistic combination therapy withย Rapamycinย in a discordant large animal donor xenoislet transplant model
  838. Studies of theย Rapamycin-sensitive signaling network using genomics, chemical genetics, and small molecule microarrays.
  839. Rapamycinย increases the expression of genes responsible for extracellular matrix remodelling compared to neoral in rat allografts
  840. Inhibitory effects ofย Rapamycinย on intimal hyperplasia after PTCA in the porcine coronary model: a 3-month follow-up
  841. Regulation of the cell integrity pathway byย Rapamycin-sensitive TOR function in budding yeast
  842. Rapamycinย Inhibits Estrogen-Mediated Transcription in Breast Cancer Cell Lines
  843. Tissue Distribution ofย Rapamycinย and Cyclosporine in the Rat: Comparison of Single vs. Dual Drug Therapy
  844. inhibitionย byย Rapamycinย of PDGF-and bFGF-induced human tenon fibroblast proliferation in vitro
  845. Effects ofย Rapamycinย and wortmannin on the insulin stimulation of protein synthesis in rat skeletal muscle and L6 myoblasts
  846. The expression of mammalian target ofย Rapamycinย in autogenous vein graft in rats
  847. The Effects of Immunosuppressantsย Rapamycinย and Cyclosporin A on the Proliferation, Cell Cycle, and Cyclin Expression of Cultured Human Keratinocyte Cell Line โ€ฆ
  848. The effects ofย Rapamycinย and cyclosporin a on tolerance induction through bone marrow transplantation with costimulation blockade
  849. Cyclosporin and FK506, but notย Rapamycin, increase DNFB induced TNF-alpha expression in human epidermal sheets.
  850. Mass spectrometric analysis of theย Rapamycin-dependent phosphorylation sites of the yeast protein kinase NPR1
  851. Effects of stent-based delivery ofย Rapamycinย and methotrexate on neointimal formation in a porcine coronary model
  852. Effects of cyclosporin andย Rapamycinย on the in vitro activation of human CD8+ lymphocytes in comparison with peripheral blood mononuclear cells.
  853. Evaluation ofย Rapamycinย coated stents by multi row detector computed angiography: comparison to quantitative angiographic results
  854. Cyclosporin A and FK506, but notย Rapamycin, increase DNFB induced TNF-alpha expression in human epidermal sheets.
  855. Using natural products to elucidate molecular events within cells: Molecular mechanisms of action of cyclosporine, FK506, andย Rapamycin.
  856. SDZ-RAD PREVENTS CYCLOSPORINE-INDUCEDย inhibitionย OF BRAIN ENERGY METABOLISM: COMPARISON WITHย Rapamycin.: Abstract# 314 Poster Board โ€ฆ
  857. Rapamycinย POTENTIATES NF-ฮบB AND AP-1 ACTIVATION IN TNF-ฮฑ TREATED PRIMARY RAT HEPATOCYTES.: Abstract# 308 Poster Board#-Session: P155-I
  858. The Mechanism of Insulin-Induced Clonal Expansion in Adipocyte Differentiationโ€“the Importance of PI3 Kinae-Rapamycin-Sensitive Pathway
  859. Inhibitory effects ofย Rapamycinย and ascomycin on hair growth induced by cyclosporin A and FK506 in mice.
  860. Effects ofย Rapamycin-treated HSP60-pulsed dendritic cells on the progression of the atherosclerotic plaque in mice
  861. inhibitionย of S6 Kinase byย Rapamycinย Blocks Maturation of Rana dybowskii Oocytes
  862. Relationship between multiple biological effects ofย Rapamycinย and theย inhibitionย of pp70 S6 protein kinase activity: Analysis in mutant clones of a T cell lymphoma.
  863. The study ofย Rapamycin-eluting polymer-coated stents to prevent restenosis in the porcine coronary injury model
  864. Differential effects of cyclosporine andย Rapamycinย on costimulation blockade induced allograft tolerance: Intragraft CTL gene expression analysis
  865. BRIEF COMMUNICATIONS: EFFECT OFย Rapamycinย ON RENAL ALLOGRAFT SURVIVAL IN CANINE RECIPIENTS TREATED WITH ANTILYMPHOCYTE SERUM โ€ฆ
  866. Rapamycinย RESCUE IN PEDIATRIC LIVER RECIPIENTS WITH TACROLIMUS TOXICITY.: Abstract# 211 Poster Board#-Session: P58-I
  867. Rapamycinย (RAPA) lowers dose requirements of cyclosporin (CsA) in renal transplant patients (RTx)
  868. โ€ฆ Lewis acid-mediated Mukaiyama aldol reaction of ฮฑ-alkoxythiolketene acetals with ฮฑ, ฮฒ-disubstituted enals: synthesis of the C26โ€“C33 segment ofย Rapamycin
  869. Rapamycinย selectively inhibits translation of mRNAs encoding elongation factor and ribosomal protein
  870. FK506 versus CSA for steroid-free synergistic combination therapy withย Rapamycinย (Rapa) in a discordant xenoislet model
  871. SHORT TERM ANTILYMPHOCYTE SERUM,ย Rapamycinย AND DONOR BONE MARROW SIGNIFICANTLY SUPPRESS ANTIDONOR ANTIBODY AND PROLONG โ€ฆ
  872. โ€ฆ studies n bioactive natural products. Part I, An approach towards the nootrophic agent huperzine A. Part II, Synthesis of the tricarbonyl subunit ofย Rapamycin
  873. EFFECT OF TACROLIMUS (FK506) AND SIROLIMUS (Rapamycin) MONO-AND COMBINATION THERAPY IN PROLONGATION OF RENAL ALLOGRAFT โ€ฆ
  874. Coadministration of neoral and the novelย Rapamycinย analog, sdzrad, to. lung allograft recipients: potentiation of immunosuppressive efficacy and reduction of toxicity โ€ฆ
  875. Rapamycinย (Rapa) And Cyclosporin A (Csa) Enhance Transforming Growth Factor Beta (TGF-ฮฒ1) Expression in Immortalized Rat Proximal Tubules (IRPTC)โ€  1840
  876. Rapamycinย (RAPA) ENHANCES TRANSFORMING GROWTH FACTOR BETA (TGF-ฮฒ1) EXPRESSION IN IMMORTALIZED RAT PROXIMAL TUBULES CELLS โ€ฆ
  877. Prevention of Arterial Restenosis byย Rapamycinย and Mycophenolate Mofetil: A New Role for Novel Immunosuppressants in the Prevention of Post-Balloon Angioplasty โ€ฆ
  878. Rapamycinย synergizes with dst plus anti-CD154 to block auto and allo-immune response and induce islet allograft engraftment in spontaneous autoimmune diabetic โ€ฆ
  879. Mating stimulate protein phosphorylation and synthesis viaย Rapamycin-and wortmannin-sensitive manner in male accessory glands of D. melanogaster
  880. Combined use of mycophenolate mofetil (MMF) andย Rapamycinย (RAPA) in prevention of acute heart allograft rejection and reversal of ongoing cardiac allograft โ€ฆ
  881. Chronic Rejection in Non-human Primates: Sirolimus (Rapamycin), but not Cyclosporin, Prevents Graft Vascular Disease (GVD) in Aortic Allografts after Acute โ€ฆ
  882. Provocative effects of the immunosuppressantsย Rapamycin, tacrolimus, and dexamethasone on Pneumocystis carinii pneumonitis in contrast to the anti-Pneumocystis โ€ฆ
  883. Synthesis of the C-21-C-42 fragment ofย Rapamycinย and total synthesis ofย Rapamycin.
  884. PMA Induced Ser/Thr Phosphorylation of IRS-1 Mediated byย Rapamycin-Sensitive Pathway
  885. Desensitization of Insulin Action through Ser/Thr Phosphorylation and Degradation of IRS-1 by Activation ofย Rapamycin-Sensitive Pathway
  886. 24 HPLC (ESI)-MS IDENTIFICATION OF SIROLIMUS (Rapamycin) METABOLITES GENERATED IN A RABBIT MICROSOMAL SYSTEM AND CONFIRMATION WITH โ€ฆ
  887. Interleukin-2 andย Rapamycinย regulation of cyclin E-Cdk2 kinase, the Cdk inhibitor, P27KIP1, and the T lymphocyte cell cycle.
  888. 192 SENSITIVE AND SPECIFIC QUANTIFICATION OF SIROLIMUS (Rapamycin) AND ITS METABOLITES IN BLOOD AND URINE OF KIDNEY GRAFT RECIPIENTS โ€ฆ
  889. OP-4. Studies towards the Total Synthesis ofย Rapamycin
  890. 74 DETERMINATION OFย Rapamycinย IN WHOLE BLOOD BY HPLC
  891. # 680 In vitro evaluation ofย Rapamycinย sensitivity and synergy with cisplatin and camptothecin in medulloblastoma
  892. Purification and characterization of a 50 kiloDalton lymphocyte-derived binding protein for cyclosporin, FK-506 andย Rapamycin.
  893. โ€ฆ from carbohydrates: Application of the (2, 3)-Wittig rearrangement of carbohydrate-derived alpha-alkoxy tertiary allylic ethers to the syntheses of Adda andย Rapamycin.
  894. Efficacy of FK-506 andย Rapamycinย in Prolongation of Allograft Rat Limb Survival
  895. # 764ย Rapamycinย effects phosphorylation of p70S6 kinase and other intermediaries in medulloblastoma
  896. I. The formal synthesis of FK-506. II. A simple synthesis of vicinal tricarbonyls. III. Studies toward the synthesis ofย Rapamycin.
  897. Glucose-induced polypyrimidine-tract-binding protein (PTB) to the 3ยด-untranslated region of the insulin mRNA is inhibited byย Rapamycin
  898. METABOLISM AND PHARMACOKINETICS OF THE NEW IMMUNOSUPPRESSANT 40-O-(2-HYDROXY)-ETHYL-Rapamycin
  899. 138ย Rapamycinย AND CYCLOSPORINE DRUG STUDIES IN THE RAT MODEL
  900. Rapamycin: an anti-cancer immunosuppressant?
  901. Determinants ofย Rapamycinย sensitivity in breast cancer cells
  902. Antileukemic activity ofย Rapamycinย in acute myeloid leukemia
  903. Molecular organization of target ofย Rapamycinย complex 2
  904. Rapamycin-induced oligospermia
  905. mTOR-targeted therapy of cancer withย Rapamycinย derivatives
  906. Rapamycinย pre-treatment protects against apoptosis
  907. Activation of Akt and eIF4E survival pathways byย Rapamycin-mediated mammalian target ofย Rapamycinย inhibition
  908. Signaling by target ofย Rapamycinย proteins in cell growth control
  909. Differential effects ofย Rapamycinย on mammalian target ofย Rapamycinย signaling functions in mammalian cells
  910. Rapamycinย alleviates toxicity of different aggregate-prone proteins
  911. Prolongedย Rapamycinย treatment inhibitsย mTORC2 assembly and Akt/PKB
  912. Rapamycinย attenuates load-induced cardiac hypertrophy in mice
  913. Use ofย Rapamycinย slows progression of cardiac transplantation vasculopathy
  914. Rapamycinย markedly slows disease progression in a rat model of polycystic kidney disease
  915. Rapamycinย selectively expands CD4+CD25+FoxP3+ regulatory T cells
  916. Rapamycinย is an effective inhibitor of human renal cancer metastasis
  917. Maintenance immunosuppression with target-of-Rapamycinย inhibitors is associated with a reduced incidence of de novo malignancies
  918. Rapamycinย causes regression of astrocytomas in tuberous sclerosis complex
  919. Campathโ€1H induction plusย Rapamycinย monotherapy for renal transplantation: results of a pilot study
  920. Phosphorylation of Mammalian Target ofย Rapamycinย (mTOR) at Ser-2448 IsMediated by p70S6 Kinase
  921. Target ofย Rapamycinย (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
  922. Pathological angiogenesis is induced by sustained Akt signaling and inhibited byย Rapamycin
  923. Characterization of the FKBPโŠ™ย RapamycinโŠ™ FRB Ternary Complex
  924. inhibitionย of target ofย Rapamycinย signaling byย Rapamycinย in the unicellular green alga Chlamydomonas reinhardtii
  925. Insulin/IGF and target ofย Rapamycinย signaling: a TOR de force in growth control
  926. Targeting the molecular target ofย Rapamycinย (mTOR)
  927. inhibitionย ofย mTORย signaling withย Rapamycinย regresses established cardiac hypertrophy induced by pressure overload
  928. The molecular target ofย Rapamycinย (mTOR) as a therapeutic target against cancer
  929. Regulation of adipocyte differentiation and insulin action withย Rapamycin
  930. Effects ofย Rapamycinย in the Eker rat model of tuberous sclerosis complex
  931. Targeting the mammalian target ofย Rapamycinย (mTOR): a new approach to treating cancer
  932. Target ofย Rapamycin-mediated amino acid signaling in mosquito anautogeny
  933. Multiple roles of Tap42 in mediatingย Rapamycin-induced transcriptional changes in yeast
  934. Rapamycinย impairs antigen uptake of human dendritic cells1
  935. Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: a randomized comparison of a simple versus complex strategy
  936. Mammalian target ofย Rapamycinย inhibitionย as therapy for hematologic malignancies
  937. Dissociation of raptor fromย mTORย is a mechanism ofย Rapamycinโ€inducedย inhibitionย ofย mTORย function
  938. GฮฒL, a positive regulator of theย Rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor andย mTOR
  939. Mammalian target ofย Rapamycin: a new molecular target for breast cancer
  940. Combination ofย Rapamycinย and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs
  941. A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target ofย Rapamycinย and its targets
  942. Immunosuppressants and skin cancer in transplant patients: focus onย Rapamycin
  943. Rapamycinย promotes expansion of functional CD4+ CD25+ FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
  944. Specific binding to intracellular proteins determines arterial transport properties forย Rapamycinย and paclitaxel
  945. Rapamycinย stimulates apoptosis of childhood acute lymphoblastic leukemia cells
  946. Targeting mammalian target ofย Rapamycinย synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells
  947. Upstream of the mammalian target ofย Rapamycin: do all roads pass throughย mTOR?
  948. Rictor, a novel binding partner ofย mTOR, defines aย Rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
  949. Phospholipase D confersย Rapamycinย resistance in human breast cancer cells
  950. Thr2446 is a novel mammalian target ofย Rapamycinย (mTOR) phosphorylation site regulated by nutrient status
  951. Nephrotoxicity ofย Rapamycin: an emerging problem in clinical medicine
  952. Rapamycinย analogs with differential binding specificity permit orthogonal control of protein activity
  953. The mammalian target ofย Rapamycinย (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
  954. Rapamycinย attenuates unilateral ureteral obstruction-induced renal fibrosis
  955. Rapamycinย reduces disease activity and normalizes T cell activationโ€“induced calcium fluxing in patients with systemic lupus erythematosus
  956. Rapamycinย suppresses experimental aortic aneurysm growth
  957. Rapamycinย is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling
  958. Rapamycinย has a deleterious effect on MIN-6 cells and rat and human islets
  959. Antiangiogenic potential of the mammalian target ofย Rapamycinย inhibitor temsirolimus
  960. Mammalian TOR complex 2 controls the actin cytoskeleton and isย Rapamycinย insensitive
  961. Rapamycinย protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice
  962. The Pim kinases controlย Rapamycin-resistant T cell survival and activation
  963. Akt activates the mammalian target ofย Rapamycinย by regulating cellular ATP level and AMPK activity
  964. Mammalian target ofย Rapamycin, a molecular target in squamous cell carcinomas of the head and neck
  965. Finding new components of the target ofย Rapamycinย (TOR) signaling network through chemical genetics and proteome chips
  966. Stent implantation activates RhoA in human arteries: inhibitory effect ofย Rapamycin
  967. Regulation of targets ofย mTORย (mammalian target ofย Rapamycin) signalling by intracellular amino acid availability.
  968. Rapamycinย for treatment of chronic allograft nephropathy in renal transplant patients
  969. Sustained activation of the JNK cascade andย Rapamycin-induced apoptosis are suppressed by p53/p21Cip1
  970. Combination of theย mTORย inhibitorย Rapamycinย and CC-5013 has synergistic activity in multiple myeloma
  971. Rapamycinย and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance
  972. Gene expression-based chemical genomics identifiesย Rapamycinย as a modulator of MCL1 and glucocorticoid resistance
  973. Rapamycinย activates Tap42โ€associated phosphatases by abrogating their association with Tor complex 1
  974. Preliminary observations regarding angiographic pattern of restenosis afterย Rapamycin-eluting stent implantation
  975. Mutasynthesis ofย Rapamycinย analogues through the manipulation of a gene governing starter unit biosynthesis
  976. Curcumin inhibits the mammalian target ofย Rapamycinโ€mediated signaling pathways in cancer cells
  977. Mammalian target ofย Rapamycinย pathway blockade slows progression of diabetic kidney disease in rats
  978. The solution structure of the FATC domain of the protein kinase target ofย Rapamycinย suggests a role for redox-dependent structural and cellular stability
  979. Mammalian target ofย Rapamycinย regulates IRS-1 serine 307 phosphorylation
  980. The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target ofย Rapamycinย pathway
  981. Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells
  982. Insights into TOR function andย Rapamycinย response: chemical genomic profiling by using a high-density cell array method
  983. Survival signaling by Notch1: mammalian target ofย Rapamycinย (mTOR)โ€“dependentย inhibitionย of p53
  984. Antitumoral activity ofย Rapamycinย in renal angiomyolipoma associated with tuberous sclerosis complex
  985. Rapamycinย successfully treats postโ€transplant autoimmune hepatitis
  986. Increased activation of the mammalian target ofย Rapamycinย pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance
  987. Rapamycin: signaling in vascular smooth muscle
  988. Therapeutic potential of target ofย Rapamycinย inhibitors
  989. Synergistic augmentation ofย Rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
  990. Rapamycinย inhibits proliferation and differentiation of human endothelial progenitor cells in vitro
  991. Rheb binding to mammalian target ofย Rapamycinย (mTOR) is regulated by amino acid sufficiency
  992. Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells
  993. Inhibitory effect ofย Rapamycinย on corneal neovascularization in vitro and in vivo
  994. Regulation of peroxisome proliferatorโ€“activated receptor-ฮณ activity by mammalian target ofย Rapamycinย and amino acids in adipogenesis
  995. inhibitionย ofย mTORย signaling withย Rapamycinย attenuates renal hypertrophy in the early diabetic mice
  996. Identification of S6 kinase 1 as a novel mammalian target ofย Rapamycinย (mTOR)-phosphorylating kinase
  997. Rapamycinย inhibits IL-4โ€”induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
  998. Mammalian target ofย Rapamycinย inhibition
  999. Phase I/II study of the mammalian target ofย Rapamycinย inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies
  1000. Mechanical stimuli regulateย Rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B-and growth factor-independent mechanism
  1001. Dosing ofย Rapamycinย is critical to achieve an optimal antiangiogenic effect against cancer
  1002. A possible linkage between AMPโ€activated protein kinase (AMPK) and mammalian target ofย Rapamycinย (mTOR) signalling pathway
  1003. Rapamycinย induces tumor-specific thrombosis via tissue factor in the presence of VEGF
  1004. Acuteย Rapamycinย nephrotoxicity in native kidneys of patients with chronic glomerulopathies
  1005. Rapamycinย sensitizes multiple myeloma cells to apoptosis induced by dexamethasone
  1006. AKT activity determines sensitivity to mammalian target ofย Rapamycinย (mTOR) inhibitors by regulating cyclin D1 and c-myc expression
  1007. Inhibitors of the mammalian target ofย Rapamycin
  1008. Homodirectional changes in transcriptome composition and mRNA translation induced byย Rapamycinย and heat shock
  1009. Rapamycin, but not FK-506, increases endothelial tissue factor expression: implications for drug-eluting stent design
  1010. Oralย Rapamycinย after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oralย Rapamycinย in Argentina (ORAR II) Study
  1011. Rapamycin-mediatedย inhibitionย of mammalian target ofย Rapamycinย in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation
  1012. Rapamycinย inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma
  1013. Rapamycinย inhibits the growth and metastatic progression of non-small cell lung cancer
  1014. Effect ofย Rapamycinย alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer
  1015. Efficacy of aย Rapamycinย analog (CCIโ€779) and IFNโ€ฮณ in tuberous sclerosis mouse models
  1016. Rapamycinย confers preconditioning-like protection against ischemiaโ€“reperfusion injury in isolated mouse heart and cardiomyocytes
  1017. Drosophila target ofย Rapamycinย kinase functions as a multimer
  1018. Targeting the Akt/mammalian target ofย Rapamycinย pathway for radiosensitization of breast cancer
  1019. A selective small molecule c-MET Inhibitor, PHA665752, cooperates withย Rapamycin
  1020. Arabidopsis TARGET OFย Rapamycinย interacts with RAPTOR, which regulates the activity of S6 kinase in response to osmotic stress signals
  1021. Rapamycinย in cardiovascular medicine
  1022. Mechanical stimuli and nutrients regulateย Rapamycinโ€sensitive signaling through distinct mechanisms in skeletal muscle
  1023. FKBP12-Rapamycin-associated protein or mammalian target ofย Rapamycinย (FRAP/mTOR) localization in the endoplasmic reticulum and the Golgi apparatus
  1024. S6K1โˆ’/โˆ’/S6K2โˆ’/โˆ’ mice exhibit perinatal lethality andย Rapamycin-sensitive 5โ€ฒ-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein โ€ฆ
  1025. Determinants of sensitivity and resistance toย Rapamycin-chemotherapy drug combinations in vivo
  1026. Brain-derived neurotrophic factor induces mammalian target ofย Rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal โ€ฆ
  1027. In vitro study of release mechanisms of paclitaxel andย Rapamycinย from drug-incorporated biodegradable stent matrices
  1028. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target ofย Rapamycinย by amino acids and certain cellular stresses
  1029. Rapamycinย inhibits cell motility by suppression ofย mTOR-mediated S6K1 and 4E-BP1 pathways
  1030. Rapamycinโ€sensitive signalling in longโ€term consolidation of auditory cortexโ€dependent memory
  1031. Systemicย Rapamycinย inhibits retinal and choroidal neovascularization in mice
  1032. inhibitionย of the mammalian target ofย Rapamycinย (mTOR) byย Rapamycinย increases chemosensitivity of CaSki cells to paclitaxel
  1033. Target ofย Rapamycinย inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of โ€ฆ
  1034. Rapamycinโ€treated, alloantigenโ€pulsed host dendritic cells induce agโ€specific T cell regulation and prolong graft survival
  1035. Activation of mammalian target ofย Rapamycinย in cytomegalic neurons of human cortical dysplasia
  1036. Mutation in TSC2 and activation of mammalian target ofย Rapamycinย signalling pathway in renal angiomyolipoma
  1037. inhibitionย of mammalian target ofย Rapamycinย or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
  1038. Role of mammalian target ofย Rapamycinย signaling in compensatory renal hypertrophy
  1039. Rapamycinย synergizes with the epidermal growth factor receptor inhibitor erlotinib in nonโ€“small-cell lung, pancreatic, colon, and breast tumors
  1040. Rapamycinย ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy
  1041. Activation of the Akt/mammalian target ofย Rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers
  1042. Autophagy for cancer therapy throughย inhibitionย of pro-apoptotic proteins and mammalian target ofย Rapamycinย signaling
  1043. BDNF regulates the translation of a select group of mRNAs by a mammalian target ofย Rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal โ€ฆ
  1044. Antitumor efficacy of intermittent treatment schedules with theย Rapamycinย derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in โ€ฆ
  1045. The mammalian target ofย Rapamycinย signaling network and gene regulation
  1046. Combination mammalian target ofย Rapamycinย inhibitorย Rapamycinย and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple โ€ฆ
  1047. Role of glycogen synthase kinase 3ฮฒ inย Rapamycin-mediated cell cycle regulation and chemosensitivity
  1048. Immediate response of mammalian target ofย Rapamycinย (mTOR)โ€mediated signalling following acute resistance exercise in rat skeletal muscle
  1049. Proteomic analysis reveals hyperactivation of the mammalian target ofย Rapamycinย pathway in neurofibromatosis 1โ€“associated human and mouse brain tumors
  1050. Rapamycinย (sirolimus) for treatment of chronic graft-versus-host disease
  1051. Mutual antagonism of target ofย Rapamycinย and calcineurin signaling
  1052. Rapamycinย inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas
  1053. inhibitionย of corneal neovascularization byย Rapamycin
  1054. Calcineurin inhibitors, but notย Rapamycin, reduce percentages of CD4+ CD25+ FOXP3+ regulatory T cells in renal transplant recipients
  1055. Androgens induce prostate cancer cell proliferation through mammalian target ofย Rapamycinย activation and post-transcriptional increases in cyclin D proteins
  1056. Dexamethasone represses signaling through the mammalian target ofย Rapamycinย in muscle cells by enhancing expression of REDD1
  1057. In vitro release of theย mTORย inhibitorย Rapamycinย from poly (ethylene glycol)-b-poly (ฮต-caprolactone) micelles
  1058. Low-dose oralย Rapamycinย treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis
  1059. Antitumor activity ofย Rapamycinย in a transgenic mouse model of ErbB2-dependent human breast cancer
  1060. Translational control via the mammalian target ofย Rapamycinย pathway is critical for the formation and stability of long-term fear memory in amygdala neurons
  1061. Rapamycinย induces Smad activity in prostate cancer cell lines
  1062. Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bฯต mRNA in a mammalian target ofย Rapamycinย โ€ฆ
  1063. Differential effect of calcineurin inhibitors, anti-CD25 antibodies andย Rapamycinย on the induction of FOXP3 in human T cells
  1064. The mammalian target ofย Rapamycinย (mTOR) partner, raptor, binds theย mTORย substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
  1065. Effects of the mammalian target ofย Rapamycinย inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts
  1066. Rapamycinย inhibits doxorubicin-induced NF-ฮบB/Rel nuclear activity and enhances the apoptosis of melanoma cells
  1067. Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complexโ€“mammalian target ofย Rapamycinย pathway
  1068. Rapamycinย induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response toย Rapamycin
  1069. New targets for therapy in breast cancer: mammalian target ofย Rapamycinย (mTOR) antagonists
  1070. Modulation of the mammalian target ofย Rapamycinย pathway by diacylglycerol kinase-produced phosphatidic acid
  1071. Human cytomegalovirus infection inducesย Rapamycin-insensitive phosphorylation of downstream effectors ofย mTORย kinase
  1072. Mammalian target ofย Rapamycinย inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor โ€ฆ
  1073. โ€ฆ predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from theย Rapamycin-Eluting Stent Evaluated At โ€ฆ
  1074. Loss of Tsc1 or Tsc2 induces vascular endothelial growth factor production through mammalian target ofย Rapamycin
  1075. Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation byย Rapamycin
  1076. Rpd3p relocation mediates a transcriptional response toย Rapamycinย in yeast
  1077. Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target ofย Rapamycinย pathway in breast cancer cells
  1078. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target ofย Rapamycinย kinase inhibitor, in patients with advanced refractory renal cell โ€ฆ
  1079. Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy
  1080. Activation of the mammalian target ofย Rapamycinย pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes
  1081. Akt1 Activation Can Augment Hypoxia-Inducible Factor-1ฮฑ Expression by Increasing Protein Translation through a Mammalian Target ofย Rapamycinโ€“Independent โ€ฆ
  1082. Rapamycinย inhibits GM-CSF-induced neutrophil migration
  1083. The mammalian target of theย Rapamycinย (mTOR) kinase pathway: its role in tumourigenesis and targeted antitumour therapy
  1084. Delayed graft function and cast nephropathy associated with tacrolimus plusย Rapamycinย use
  1085. Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in theย Rapamycinย gene cluster
  1086. Recent developments in targeting the mammalian target ofย Rapamycinย (mTOR) kinase pathway
  1087. Domains of Gln3p interacting with karyopherins, Ure2p, and the target ofย Rapamycinย protein
  1088. Rapamycin-eluting stents for the treatment of unprotected left main coronary disease
  1089. Rapamycinย induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation
  1090. Activation of mammalian target ofย Rapamycinย signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinaseโ€“positive anaplastic large cell โ€ฆ
  1091. Rapamycin-induced endothelial cell death and tumor vessel thrombosis potentiate cytotoxic therapy against pancreatic cancer
  1092. Activation of mammalian target ofย Rapamycinย (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimericย mTORย complex 1
  1093. Mammalian target ofย Rapamycinย inhibitionย promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma โ€ฆ
  1094. inhibitionย of mammalian target ofย Rapamycinย reverses alveolar epithelial neoplasia induced by oncogenic K-ras
  1095. Raptor, a binding partner of target ofย Rapamycin
  1096. Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring โ€ฆ
  1097. Rapamycinย improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)
  1098. Molecular mechanisms through which amino acids mediate signaling through the mammalian target ofย Rapamycin
  1099. โ€ฆ outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from theย Rapamycin-Eluting and Taxus Stent โ€ฆ
  1100. Rapamycinย biosynthesis: elucidation of gene product function
  1101. Effect ofย Rapamycinย on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Eฮผ-TCL1 transgenic mice
  1102. Roles of glutamate receptors and the mammalian target ofย Rapamycinย (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in โ€ฆ
  1103. Newย Rapamycinย derivatives by precursorโ€directed biosynthesis
  1104. Thyroid Hormone Induces Rapid Activation of Akt/Protein Kinase B-Mammalian Target ofย Rapamycin-p70S6K Cascade through Phosphatidylinositol 3-Kinase in โ€ฆ
  1105. Target ofย Rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito
  1106. inhibitionย of mammalian target ofย Rapamycinย activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity
  1107. โ€ฆ growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย (PI3K/Akt/mTOR) โ€ฆ
  1108. Novel role of the small GTPase Rheb: its implication in endocytic pathway independent of the activation of mammalian target ofย Rapamycin
  1109. Chronicย inhibitionย of mammalian target ofย Rapamycinย signaling downregulates insulin receptor substrates 1 and 2 and AKT activation: a crossroad between cancer and โ€ฆ
  1110. Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2ฮฑ kinase GCN2
  1111. Control of dendritic arborization by the phosphoinositide-3โ€ฒ-kinaseโ€“Aktโ€“mammalian target ofย Rapamycinย pathway
  1112. Rapamycinย induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewingโ€™s sarcoma cell proliferation
  1113. Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin
  1114. Mammalian target ofย Rapamycinย as a therapeutic target in leukemia
  1115. Activation of mammalian target ofย Rapamycinย signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma
  1116. Nutrient-dependent multimerization of the mammalian target ofย Rapamycinย through the N-terminal HEAT repeat region
  1117. Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target ofย Rapamycin
  1118. Mammalian target ofย Rapamycinย (mTOR) inhibitors as anti-cancer agents
  1119. Long-term treatment of bile duct-ligated rats withย Rapamycinย (sirolimus) significantly attenuates liver fibrosis: analysis of the underlying mechanisms
  1120. Mechanism by which mammalian target ofย Rapamycinย inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis
  1121. Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target ofย Rapamycin
  1122. Mammalian target ofย Rapamycinย inhibitionย induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitises DLBCL cells to rituximab
  1123. Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response toย Rapamycinย in an Akt-dependent manner via p38 MAPK signaling
  1124. Theย Rapamycinย analog CCI-779 is a potent inhibitor of pancreatic cancer cell proliferation
  1125. Pilot trial of oralย Rapamycinย for recalcitrant restenosis
  1126. Effect ofย Rapamycinย on renal ischemiaโ€reperfusion injury in mice
  1127. Rapamycinย delays but does not prevent recovery from acute renal failure: role of acquired tubular resistance
  1128. ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target ofย Rapamycin/p70S6K leading to increased angiogenesis and โ€ฆ
  1129. Rapamycinย specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression
  1130. Successful conversion toย Rapamycinย for calcineurin inhibitor-related neurotoxicity following liver transplantation
  1131. Synergistic effect of targetingย mTORย byย Rapamycinย and depleting ATP byย inhibitionย of glycolysis in lymphoma and leukemia cells
  1132. Cyclosporin A and tacrolimus, but notย Rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells
  1133. Rapamycinย inhibits growth and survival of D816V-mutated c-kit mast cells
  1134. United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target ofย Rapamycinย (mTOR) signalling
  1135. Target ofย Rapamycinย (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding โ€ฆ
  1136. โ€ฆ sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growthย inhibitionย viaย inhibitionย of mammalian target ofย Rapamycinย โ€ฆ
  1137. Rapamycinย attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27Kip1-independent pathway
  1138. Mammalian target ofย Rapamycinย positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway
  1139. Human cytomegalovirus infection alters the substrate specificities andย Rapamycinย sensitivities of raptor-and rictor-containing complexes
  1140. Regulation of Leucine Uptake by tor1+ in Schizosaccharomyces pombe Is Sensitive toย Rapamycin
  1141. TCR engagement increases hypoxia-inducible factor-1ฮฑ protein synthesis viaย Rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells
  1142. Early outcome after sirolimus-eluting stent implantation in patients with acute coronary syndromes: insights from theย Rapamycin-Eluting Stent Evaluated At Rotterdam โ€ฆ
  1143. Mammalian target ofย Rapamycinย (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation
  1144. Local application ofย Rapamycinย inhibits neointimal hyperplasia in experimental vein grafts
  1145. Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced byย Rapamycinย through a p38 MAPK โ€ฆ
  1146. GATA factor translation is the final downstream step in the amino acid/target-of-Rapamycin-mediated vitellogenin gene expression in the anautogenous โ€ฆ
  1147. Rapamycinย attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxis
  1148. Rapamycinย attenuates vascular wall inflammation and progenitor cell promoters after angioplasty
  1149. Akt1/Akt2 and mammalian target ofย Rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell โ€ฆ
  1150. Fibronectin stimulates nonโ€“small cell lung carcinoma cell growth through activation of Akt/mammalian target ofย Rapamycin/S6 kinase and inactivation of LKB1/AMP โ€ฆ
  1151. Activation of the phosphoinositide 3-kinase-Akt-mammalian target ofย Rapamycinย signaling pathway is required for metabotropic glutamate receptor-dependent long โ€ฆ
  1152. Rapamycinย causes down-regulation of CCR5 and accumulation of anti-HIV ฮฒ-chemokines: an approach to suppress R5 strains of HIV-1
  1153. โ€ฆ in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinsonโ€™s disease by a mechanism involving mammalian target ofย Rapamycinย โ€ฆ
  1154. Glucagon represses signaling through the mammalian target ofย Rapamycinย in rat liver by activating AMP-activated protein kinase
  1155. Isolation and Characterization of Preโ€Rapamycin, the First Macrocyclic Intermediate in the Biosynthesis of the Immunosuppressantย Rapamycinย by S. hygroscopicus
  1156. Type D personality predicts death or myocardial infarction after bare metal stent or sirolimus-eluting stent implantation: aย Rapamycin-Eluting Stent Evaluated at โ€ฆ
  1157. A high-throughput method for screening ofย Rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates
  1158. Phosphatidic acid regulates systemic inflammatory responses by modulating the Akt-mammalian target ofย Rapamycin-p70 S6 kinase 1 pathway
  1159. Comparative effects of paclitaxel andย Rapamycinย on smooth muscle migration and survival: role of AKT-dependent signaling
  1160. Production of novelย Rapamycinย analogs by precursor-directed biosynthesis
  1161. Rapamycinย inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells1
  1162. Effects ofย Rapamycinย on number activity and eNOS of endothelial progenitor cells from peripheral blood
  1163. Predictive and prognostic role of activated mammalian target ofย Rapamycinย in cervical cancer treated with cisplatin-based neoadjuvant chemotherapy
  1164. Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target ofย Rapamycinย (mTOR)-induced negative feedback down-regulates โ€ฆ
  1165. Aย Rapamycinย derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein ฮฒ and NF-ฮบB activity in Hodgkin and โ€ฆ
  1166. Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target ofย Rapamycinย and for recognition by raptor
  1167. A nuclear transport signal in mammalian target ofย Rapamycinย is critical for its cytoplasmic signaling to S6 kinase 1
  1168. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target ofย Rapamycinย (mTOR)-independent
  1169. โ€ฆ undergoing percutaneous intervention in the drug-eluting stent era: an integrated clinical and angiographic analysis based on theย Rapamycin-Eluting Stent Evaluated โ€ฆ
  1170. Antiangiogenic and immunomodulatory effects ofย Rapamycinย on islet endothelium: relevance for islet transplantation
  1171. Rapamycinย mimics the incompatibility reaction in the fungus Podospora anserina
  1172. Rapamycinย effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties
  1173. An open prospective pilot study on the use ofย Rapamycinย after penetrating high-risk keratoplasty
  1174. Ex vivoย Rapamycinย generates Th1/Tc1 or Th2/Tc2 Effector T cells with enhanced in vivo function and differential sensitivity to post-transplantย Rapamycinย therapy
  1175. Post-transcriptional regulation of the androgen receptor by Mammalian target ofย Rapamycin
  1176. Rapamycinย induces apoptosis of JN-DSRCT-1 cells by increasing the Bax: Bcl-xL ratio through concurrent mechanisms dependent and independent of its โ€ฆ
  1177. Efficacy ofย Rapamycinย in patient with juvenile rheumatoid arthritis
  1178. Mammalian target ofย Rapamycinย (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation
  1179. Effects ofย Rapamycinย on accumulation of ฮฑโ€, ฮฒโ€ and ฮณโ€globin mRNAs in erythroid precursor cells from ฮฒโ€thalassaemia patients
  1180. Rapamycinย and chronic kidney disease: beyond theย inhibitionย of inflammation
  1181. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target ofย Rapamycinย pathway
  1182. inhibitionย of the mammalian target ofย Rapamycinย and the induction of cell cycle arrest in mantle cell lymphoma cells
  1183. LY294002 andย Rapamycinย coโ€operate to inhibit Tโ€cell proliferation
  1184. Theย mTORย inhibitorย Rapamycinย down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells
  1185. The immunosuppressantย Rapamycinย exacerbates neurotoxicity of Aฮฒ peptide
  1186. โ€ฆ transcriptionally and posttranslationally through phosphatidylinositol 3โ€ฒ-kinase/Akt, heat shock protein 90, and mammalian target ofย Rapamycinย in transformed NK โ€ฆ
  1187. From Rapa Nui toย Rapamycin: targeting PI3K/Akt/mTORย for cancer therapy
  1188. Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target ofย Rapamycinย (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways โ€ฆ
  1189. Statins induce mammalian target ofย Rapamycinย (mTOR)-mediatedย inhibitionย of Akt signaling and sensitize p53-deficient cells to cytostatic drugs
  1190. Target ofย Rapamycinย inhibitors (TORโ€I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients
  1191. Phophatidylinositol-3 Kinase/Mammalian Target ofย Rapamycin/p70S6K Regulates Contractile Protein Accumulation in Airway Myocyte Differentiation
  1192. Amino acid signaling through the mammalian target ofย Rapamycinย (mTOR) pathway: role of glutamine and of cell shrinkage
  1193. Rapamycin: friend, foe, or misunderstood?
  1194. Rapamycinย inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ
  1195. The product of the UTH1 gene, required for Baxโ€induced cell death in yeast, is involved in the response toย Rapamycin
  1196. Effects of FK506 andย Rapamycinย on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes
  1197. Sustained intraocularย Rapamycinย delivery effectively prevents high-risk corneal allograft rejection and neovascularization in rabbits
  1198. Effects ofย Rapamycinย on the epithelial-to-mesenchymal transition of human peritoneal mesothelial cells
  1199. Mammalian target ofย Rapamycin
  1200. Rapamycinย analogs for stent-based local drug delivery
  1201. Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target ofย Rapamycinย pathway
  1202. Differential effects of immunosuppressive drugs on chemokine receptor CCR7 in human monocyte-derived dendritic cells: selective upregulation byย Rapamycin
  1203. Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target ofย Rapamycinย activity and increased translation under hypoxic conditions
  1204. Rapamycinย disrupts cyclin/cyclin-dependent kinase/p21/proliferating cell nuclear antigen complexes and cyclin D1 reversesย Rapamycinย action by stabilizing these โ€ฆ
  1205. Mechanisms of action ofย Rapamycinย in gliomas
  1206. Enhancement of translation elongation in neurons by brainโ€derived neurotrophic factor: Implications for mammalian target ofย Rapamycinย signaling
  1207. Oralย Rapamycinย to inhibit restenosis after stenting of de novo coronary lesions: the Oral Rapamune to Inhibit Restenosis (ORBIT) study
  1208. Effects of combined treatment withย Rapamycinย and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts
  1209. Group I metabotropic glutamate receptors activate the p70S6 kinase via both mammalian target ofย Rapamycinย (mTOR) and extracellular signal-regulated kinase (ERK โ€ฆ
  1210. Rapamycinย and tumor growth: mechanisms behind its anticancer activity
  1211. inhibitionย of mammalian target ofย Rapamycinย potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-ฮบB โ€ฆ
  1212. Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target ofย Rapamycinย signaling pathway
  1213. Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target ofย Rapamycinย nutrient sensing pathway
  1214. Rituximab in association withย Rapamycinย for post-transplant lymphoproliferative disease treatment
  1215. โ€ฆ macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and aย Rapamycin-sensitive,ย mTOR-related โ€ฆ
  1216. Rapamycinโ€mediated induction of ฮณโ€globin mRNA accumulation in human erythroid cells
  1217. Differing responses of Gat1 and Gln3 phosphorylation and localization toย Rapamycinย and methionine sulfoximine treatment in Saccharomyces cerevisiae
  1218. Mammalian target ofย Rapamycinย inhibitors in combination with letrozole in breast cancer
  1219. โ€ฆ 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target ofย Rapamycinย signaling pathway and โ€ฆ
  1220. Rapamycinย does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells
  1221. Combination therapy of mycophenolate mofetil andย Rapamycinย in prevention of chronic renal allograft rejection in the rat1
  1222. Rapamycinย worsens renal function and intratubular cast formation in protein overload nephropathy
  1223. Synergisticย inhibitionย of human neuroblastoma-related angiogenesis by vinblastine andย Rapamycin
  1224. Rapamycinย inhibits human renal epithelial cell proliferation: effect on cyclin D3 mRNA expression and stability
  1225. โ€ฆ identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib andย Rapamycin
  1226. Gln3 phosphorylation and intracellular localization in nutrient limitation and starvation differ from those generated byย Rapamycinย inhibitionย of Tor1/2 in โ€ฆ
  1227. Rapamycinย preserves renal function compared with cyclosporine A after ischemia/reperfusion injury
  1228. โ€ฆ -inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target ofย Rapamycinย (mTOR) pathway is โ€ฆ
  1229. Superior T-cell suppression byย Rapamycinย and FK506 overย Rapamycinย and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory โ€ฆ
  1230. Estrogen-induced activation of mammalian target ofย Rapamycinย is mediated via tuberin and the small GTPase Ras homologue enriched in brain
  1231. โ€ฆ progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย pathway: progesterone receptor as โ€ฆ
  1232. Acceleration of apoptosis in CD4+ CD8+ thymocytes byย Rapamycinย accompanied by increased CD4+ CD25+ T cells in the periphery1
  1233. Intracellular network of phosphatidylinositol 3โ€kinase, mammalian target of theย Rapamycin/70 kDa ribosomal S6 kinase 1, and mitogenโ€activated protein kinases โ€ฆ
  1234. Interleukin-12-induced interferon-ฮณ production by human peripheral blood T cells is regulated by mammalian target ofย Rapamycinย (mTOR)
  1235. Pilot study of oralย Rapamycinย to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial)
  1236. โ€ฆ artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target ofย Rapamycin/p70 ribosomal S6 kinase โ€ฆ
  1237. Interferon ฮฑ-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target ofย Rapamycinย signaling pathway
  1238. ROS fusion tyrosine kinase activates a SH2 domainโ€“containing phosphatase-2/phosphatidylinositol 3-Kinase/mammalian target ofย Rapamycinย signaling axis to form โ€ฆ
  1239. Hyperactivation of mammalian target ofย Rapamycinย (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase
  1240. Oralย Rapamycinย inhibits growth of atherosclerotic plaque in apoE knock-out mice
  1241. Rapamycin, anย mTORย inhibitor, disrupts triglyceride metabolism in guinea pigs
  1242. inhibitionย of insulin signaling and adipogenesis byย Rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1
  1243. Stable expression of small interfering RNA sensitizes TEL-PDGFฮฒR toย inhibitionย with imatinib orย Rapamycin
  1244. Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target ofย Rapamycin
  1245. Insulin-like growth factor I-mediated protection fromย Rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3โ€ฒ-kinase-Akt signaling โ€ฆ
  1246. Efficacy of polyphenon E, red ginseng, andย Rapamycinย on benzo (a) pyrene-induced lung tumorigenesis in A/J mice
  1247. โ€ฆ ofย mTORย as a novel bifunctional target in chronic myeloid leukemia: dissection of growthโ€inhibitory and VEGFโ€suppressive effects ofย Rapamycinย in leukemic cells
  1248. Sustained activation of the mammalian target ofย Rapamycinย nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in โ€ฆ
  1249. Rapamycinย antagonizes NF-ฮบB nuclear translocation activated by TNF-ฮฑ in primary vascular smooth muscle cells and enhances apoptosis
  1250. Rapamycinย inhibits fibronectin-induced migration of the human arterial smooth muscle line (E47) through the mammalian target ofย Rapamycin
  1251. Rapamycinย (sirolimus) as a steroid-sparing agent in dermatomyositis
  1252. Mammalian target ofย Rapamycinย (mTOR) inhibitors
  1253. Glucose-stimulated DNA synthesis through mammalian target ofย Rapamycinย (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent โ€ฆ
  1254. Targeting the AIB1 oncogene through mammalian target ofย Rapamycinย inhibitionย in the mammary gland
  1255. Activation of mammalian target ofย Rapamycinย in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular โ€ฆ
  1256. Sirolimus-eluting stents remain superior to bare-metal stents at two years: medium-term results from theย Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology โ€ฆ
  1257. Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in aย Rapamycin-and farnesylation-dependent manner
  1258. Rapamycinย analogs with reduced systemic exposure
  1259. Mammalian target ofย Rapamycinย and protein kinase A signaling mediate the cardiac transcriptional response to glutamine
  1260. Rapamycinย decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis
  1261. Exerciseโ€induced alterations in extracellular signalโ€regulated kinase 1/2 and mammalian target ofย Rapamycinย (mTOR) signalling to regulatory mechanisms of mRNA โ€ฆ
  1262. Mechanistic insights into impaired dendritic cell function byย Rapamycin:ย inhibitionย of Jak2/Stat4 signaling pathway
  1263. Cyclin D3 is down-regulated byย Rapamycinย in HER-2-overexpressing breast cancer cells
  1264. Rapamycinย in children after liver transplantation
  1265. inhibitionย of the phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย pathway in hematologic malignancies
  1266. Rapamycinย and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal โ€ฆ
  1267. Activation of mammalian target ofย Rapamycinย in postmenopausal ovarian endometriosis
  1268. Fatal infection afterย Rapamycinย eluting coronary stent implantation
  1269. Effect ofย Rapamycinย on the healing of the bile duct
  1270. Rapamycinย in lung transplantation
  1271. Evidence for cyclin D3 as a novel target ofย Rapamycinย in human T lymphocytes
  1272. Rapamycinย in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation
  1273. Lipase-catalyzed regioselective esterification ofย Rapamycin: synthesis of temsirolimus (CCI-779)
  1274. Role of oralย Rapamycinย to prevent restenosis in patients with de novo lesions undergoing coronary stenting: results of the Argentina single centre study (ORAR trial)
  1275. Structure-based design of AP23573, a phosphorus-containing analog ofย Rapamycinย for anti-tumor therapy.
  1276. Rapamycinย inhibits proliferation of human neuroblastoma cells without suppression of MycN
  1277. Rapamycinย inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest
  1278. โ€ฆ of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target ofย Rapamycinย (RAD001) offers improved โ€ฆ
  1279. Ex vivoย Rapamycinย generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism
  1280. Studies investigating pretransplant donor-specific blood transfusion,ย Rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin โ€ฆ
  1281. Early renal benefit ofย Rapamycinย combined with reduced calcineurin inhibitor dose in pediatric heart transplantation patients
  1282. inhibitionย of the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung โ€ฆ
  1283. โ€ฆ Receptor Substrate-1 on Ser307 and Ser612 and Impairs the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target ofย Rapamycinย Insulin Biosynthetic Pathway in โ€ฆ
  1284. Insulin facilitation of muscle protein synthesis following resistance exercise in hindlimb-suspended rats is independent of aย Rapamycin-sensitive pathway
  1285. The role of heme oxygenase 1 inย Rapamycin-induced renal dysfunction after ischemia and reperfusion injury
  1286. Rapamycinย inhibits human in stent restenosis vascular smooth muscle cells independently of pRB phosphorylation and p53
  1287. Synergistic growthย inhibitionย by Iressa andย Rapamycinย is modulated by VHL mutations in renal cell carcinoma
  1288. Perturbed IFN-ฮณ-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects ofย Rapamycin-IFN-ฮณ treatment
  1289. Roles of phosphatidylinositol 3โ€ฒ-kinase and mammalian target ofย Rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial โ€ฆ
  1290. EFFECT OFย Rapamycinย ON THE FATE OF P23H OPSIN ASSOCIATED WITH RETINITS PIGMENTOSA (AN AMERICAN OPHTHALMOLOGICAL SOCIETY โ€ฆ
  1291. Synergistic immunosuppressive effects of rosmarinic acid andย Rapamycinย in vitro and in vivo1
  1292. Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus,ย Rapamycin, and anti-interleukin-2 antibody1
  1293. Signaling interactions ofย Rapamycinย combined with erlotinib in cervical carcinoma xenografts
  1294. Rapamycinย inhibits release of tumor necrosis factor-[alpha] from human vascular smooth muscle cells
  1295. CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย pathway
  1296. Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target ofย Rapamycin/p70 S6K pathway
  1297. Mammalian target ofย Rapamycinย is required for thrombopoietinโ€induced proliferation of megakaryocyte progenitors
  1298. The fission yeast TOR proteins and theย Rapamycinย response: an unexpected tale
  1299. Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamuneยฎ,ย Rapamycin) in pediatric patients with stable chronic renal failure undergoing โ€ฆ
  1300. Use ofย Rapamycin-impregnated stents in coronary arteries
  1301. In Vivo and In Vitro Effects of SAR 943, aย Rapamycinย Analogue, on Airway Inflammation and Remodeling
  1302. Farnesylthiosalicylic Acid Inhibits Mammalian Target ofย Rapamycinย (mTOR) Activity Both in Cells and in Vitro by Promoting Dissociation of theย mTOR-Raptor Complex
  1303. Regulation of microtubule-dependent protein transport by the TSC2/mammalian target ofย Rapamycinย pathway
  1304. Pharmacokinetics of sirolimus (Rapamycin) in subjects with mild to moderate hepatic impairment
  1305. Low-dose radiation plusย Rapamycinย promotes long-term bone marrow chimerism
  1306. Rapamycin-coated expanded polytetrafluoroethylene bypass grafts exhibit decreased anastomotic neointimal hyperplasia in a porcine model
  1307. Antiโ€“third-party veto CTLs overcome rejection of hematopoietic allografts: synergism withย Rapamycinย and BM cell dose
  1308. Combination of imatinib withย Rapamycinย or RAD001 acts synergistically only in Bcr-Abl-positive cells with moderate resistance to imatinib
  1309. Outcomes of using Firebirdย Rapamycinย eluting stents in routine coronary intervention practice: one-year results from the pilot study of Firebird in China registry
  1310. Prolactin activates mammalian target-of-Rapamycinย through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 โ€ฆ
  1311. Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drugย Rapamycin: A direct role as an antifibrotic agent?
  1312. Pmr1, a Golgi Ca2+/Mn2+-ATPase, is a regulator of the target ofย Rapamycinย (TOR) signaling pathway in yeast
  1313. Rapamycinย ameliorates experimental autoimmune myocarditis
  1314. First experience withย Rapamycin-based immunosuppression to improve kidney function after heart transplantation
  1315. Three-year clinical follow-up of the unrestricted use of sirolimus-eluting stents as part of theย Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital โ€ฆ
  1316. The mammalian target ofย Rapamycin-p70 ribosomal S6 kinase but not phosphatidylinositol 3-kinase-Akt signaling is responsible for fibroblast growth factor-9 โ€ฆ
  1317. Differential effects ofย Rapamycin, cyclosporine A, and FK506 on human coronary artery smooth muscle cell proliferation and signalling
  1318. Rapamycinย causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells
  1319. Rapamycin: a new string to the antiproteinuric bow?
  1320. โ€ฆ the treatment of distal left main coronary artery disease in the drug-eluting stenting era. Clinical and angiographic insights into theย Rapamycin-Eluting Stent Evaluated โ€ฆ
  1321. Mammalian target ofย Rapamycinย inhibitors in sarcomas
  1322. Liposomal formulations of tacrolimus andย Rapamycinย increase graft survival and fiber outgrowth of dopaminergic grafts
  1323. Rapamycinย treatment is associated with an increased apoptosis rate in experimental vein grafts
  1324. 5โ€HT stimulates eEF2 dephosphorylation in aย Rapamycinโ€sensitive manner in Aplysia neurites
  1325. Blockage of 2-deoxy-D-ribose-induced angiogenesis withย Rapamycinย counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer โ€ฆ
  1326. Rapamycinย in lung transplantation: preliminary results
  1327. Tsc1 haploinsufficiency without mammalian target ofย Rapamycinย activation is sufficient for renal cyst formation in Tsc1+/โˆ’ mice
  1328. Novel sulfur-containingย Rapamycinย analogs prepared by precursor-directed biosynthesis
  1329. Rapamycinย inhibits Akt-mediated oncogenic transformation and tumor growth
  1330. Synergisticย inhibitionย of human melanoma proliferation by combination treatment with B-Raf inhibitor BAY43-9006 andย mTORย inhibitorย Rapamycin
  1331. Akt and mammalian target ofย Rapamycinย regulate separate systems of proteolysis in renal tubular cells
  1332. โ€ฆ with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target ofย Rapamycinย in breast cancer
  1333. Mammalian target ofย Rapamycinย regulates the growth of mammary epithelial cells through the inhibitor of deoxyribonucleic acid binding Id1 and their functional โ€ฆ
  1334. The effect ofย Rapamycinย on the healing of the ureteric anastomosis and wound healing
  1335. Effect of SU11248 on gastrointestinal stromal tumorโ€T1 cells: Enhancement of growthย inhibitionย viaย inhibitionย of 3โ€kinase/Akt/mammalian target ofย Rapamycinย signaling
  1336. Combination of aย Rapamycinย analog (CCIโ€779) and interferonโ€ฮณ is more effective than single agents in treating a mouse model of tuberous sclerosis complex
  1337. Overcoming T cellโ€“mediated rejection of bone marrow allografts by T-regulatory cells: Synergism with veto cells andย Rapamycin
  1338. Routine sirolimus eluting stent implantation for unselected in-stent restenosis: insights from theย Rapamycinย eluting stent evaluated at Rotterdam Cardiology Hospital โ€ฆ
  1339. Rapamycinย inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation
  1340. โ€ฆ is regulated by phosphorylation and turnover of protein kinase C ฮฒII mediated by phosphatidylinositol 3-kinase-and mammalian target ofย Rapamycinย โ€ฆ
  1341. Rapamycinย rescue therapy in patients after kidney transplantation: first clinical experience
  1342. Heme oxygenase-1 mediates the protective effects ofย Rapamycinย in monocrotaline-induced pulmonary hypertension
  1343. Successful treatment of a severe case of idiopathic pulmonary fibrosis withย Rapamycin
  1344. Evaluation ofย Rapamycinย chemical stability in volatile-organic solvents by HPLC
  1345. Characterization of the cloned full-length and a truncated human target ofย Rapamycin: activity, specificity, and enzymeย inhibitionย as studied by a high capacity assay
  1346. Rapamycinย reduces neointima formation during vascular injury.
  1347. Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target ofย Rapamycinย (mTOR) signaling pathway in aged skeletal muscle
  1348. Effects ofย Rapamycinย on the arterial inflammatory response in atherosclerotic plaques in Apo-E knockout mice
  1349. Effects of cyclosporin A and aย Rapamycinย derivative (SAR943) on chronic allergic inflammation in sensitized rats
  1350. Rapamycinย induces a caspaseโ€independent cell death in human monocytes
  1351. Acute renal failure following kidney transplantation associated with myoglobinuria in patients treated withย Rapamycin
  1352. Rapamycinย inhibits cdk4 activation, p 21WAF1/CIP1 expression and G1โ€phase progression in transformed mouse fibroblasts
  1353. Oralย Rapamycinย to prevent human coronary stent restenosis: a pilot study
  1354. A downstream kinase of the mammalian target ofย Rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability
  1355. Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of โ€ฆ
  1356. In rat hepatocytes glucagon increases mammalian target ofย Rapamycinย phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream โ€ฆ
  1357. Podospora anserina target ofย Rapamycin
  1358. Mammalian target ofย Rapamycinย and 3-phosphatidylinositol 3-kinase pathwayย inhibitionย enhances growthย inhibitionย of transforming growth factor-ฮฒ1 in prostate cancer โ€ฆ
  1359. Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but notย Rapamycinย treatment in Saccharomyces cerevisiae
  1360. Post-Rapamycinย proteinuria: incidence, evolution, and therapeutic handling at a single center
  1361. Farnesylthiosalicylic acid blocks mammalian target ofย Rapamycinย signaling in breast cancer cells
  1362. Prevention of lethal acute GVHD with an agonistic CD28 antibody andย Rapamycin
  1363. Effects of simian virus 40 large and small tumor antigens on mammalian target ofย Rapamycinย signaling: small tumor antigen mediates hypophosphorylation of eIF4E โ€ฆ
  1364. Rapamycinโ€sensitive induction of eukaryotic initiation factor 4F in regenerating mouse liver
  1365. Nutrient restriction differentially modulates the mammalian target ofย Rapamycinย signaling and the ubiquitin-proteasome system in skeletal muscle of cows and their โ€ฆ
  1366. The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response toย Rapamycinย exposure
  1367. Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects ofย Rapamycinย and simvastatin
  1368. Mammalian target ofย Rapamycinย (mTOR)ย inhibitionย in chronic lymphocytic B-cell leukemia: a new therapeutic option
  1369. โ€ฆ and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-ฮณ is regulated by mammalian target ofย Rapamycin
  1370. The influence of theย Rapamycin-derivate SDZ RAD on the healing of airway anastomoses
  1371. Cilomilast, tacrolimus andย Rapamycinย modulate dendritic cell function in the elicitation phase of allergic contact dermatitis
  1372. The impact of cyclosporine dose reduction with or without the addition ofย Rapamycinย on functional, molecular, and histological markers of chronic allograft nephropathy
  1373. Role of endothelin-1 and nitric oxide bioavailability in transplant-related vascular injury: comparative effects ofย Rapamycinย and cyclosporine
  1374. Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target ofย Rapamycin-dependent โ€ฆ
  1375. Mammalian target ofย Rapamycinย is a promising target for novel therapeutic strategy against cancer.
  1376. Effects of cyclosporin A, FK506 andย Rapamycinย on calcineurin phosphatase activity in mouse brain
  1377. Both mitogen activated protein kinase and the mammalian target ofย Rapamycinย modulate the development of functional renal proximal tubules in matrigel
  1378. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target ofย Rapamycinย is necessary for hypoxia-induced pulmonary artery adventitial fibroblast โ€ฆ
  1379. Effects ofย Rapamycinย on cardiac and skeletal muscle contraction and crossbridge cycling
  1380. Frap, FKBP12ย Rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene
  1381. Farnesyltransferase inhibitors reverse altered growth and distribution of actin filaments in Tsc-deficient cells viaย inhibitionย of bothย Rapamycin-sensitive and-insensitive โ€ฆ
  1382. Modulation of translationโ€initiation in CHOโ€K1 cells byย Rapamycinโ€induced heterodimerization of engineered eIF4G fusion proteins
  1383. Rapamycinย antagonizes cyclosporin Aโ€and tacrolimus (FK506)โ€mediated augmentation of linker for activation of T cell expression in T cells
  1384. Activation of mammalian target ofย Rapamycinย and the p70 S6 kinase by arsenic trioxide in BCR-ABLโ€“expressing cells
  1385. Proteomic analysis of antiโ€angiogenic effects by a combined treatment with vinblastine andย Rapamycinย in an endothelial cell line
  1386. The PCPH oncoprotein antagonizes the proapoptotic role of the mammalian target ofย Rapamycinย in the response of normal fibroblasts to ionizing radiation
  1387. Sirolimus (Rapamycin) monotherapy prevents graft vascular disease in nonhuman primate recipients of orthotopic aortic allografts
  1388. Mammalian target ofย Rapamycinย inhibitors in renal cell carcinoma: current status and future applications
  1389. Investigating mammalian target ofย Rapamycinย inhibitors for their anticancer properties
  1390. Rapamycinย treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae
  1391. Theย Rapamycinย derivative RAD inhibits mesangial cell migration through the CDK-inhibitor p27 Kip1
  1392. Combination therapy for treating breast cancer using antiestrogen, ERA-923, and the mammalian target ofย Rapamycinย inhibitor, temsirolimus
  1393. Generatingย Rapamycinย analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids
  1394. Electron microscopic and biochemical study of the effects ofย Rapamycinย on glycogen autophagy in the newborn rat liver
  1395. โ€ฆ 4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target ofย Rapamycinย (mTOR)-and non โ€ฆ
  1396. Rapamycinย in patients with chronic renal allograft dysfunction
  1397. Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target ofย Rapamycin, and ribosomal S6 kinase 1 signaling pathways โ€ฆ
  1398. โ€ฆ of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target ofย Rapamycinย and ribosomal p70s6 kinase
  1399. Rapamycinย inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells
  1400. Targeting metastatic leiomyosarcoma byย Rapamycinย plus gemcitabine: an intriguing clinical observation
  1401. Vanadate andย Rapamycinย synergistically enhance insulin-stimulated glucose uptake
  1402. Rapamycinย control of transgene expression from a single AAV vector in mouse salivary glands
  1403. Cutaneous leukocytoclastic vasculitis in a patient with myelodysplatic syndrome after therapy with theย Rapamycinย analogue everlimus: Case report and review of the โ€ฆ
  1404. Determining sensitivity toย Rapamycinย and its analogues in breast cancer patients
  1405. Rapamycinย preโ€treatment preserves viability, ATP level and catabolic capacity during carbon starvation of Saccharomyces cerevisiae
  1406. Rapamycinย and FK506 reduce skeletal muscle voltage sensor expression and function
  1407. Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target ofย Rapamycin, and p70 S6 kinase โ€ฆ
  1408. Theย mTORย pathway in estrogen response: A potential for combining theย Rapamycinย derivative RAD001 with the aromatase inhibitor Letrozole (Femaraยฎ) in breast โ€ฆ
  1409. inhibitionย of mammalian target ofย Rapamycinย modulates expression of adhesion molecules in endothelial cells
  1410. SUMO modification throughย Rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes
  1411. Cyclosporine andย Rapamycinย act in a synergistic and dose-dependent manner in a model of immunosuppressant-induced kidney damage
  1412. Current Data with Mammalian Target ofย Rapamycinย Inhibitors in Advanced Renal Cell Carcinoma
  1413. Novel siteโ€specific systemic delivery ofย Rapamycinย with perfluorobutane gas microbubble carrier reduced neointimal formation in a porcine coronary restenosis model
  1414. The phosphatase subunit tap42 functions independently of target ofย Rapamycinย to regulate cell division and survival in Drosophila
  1415. Rapamycinย control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer
  1416. Farnesyltransferase inhibitors andย Rapamycinย in the treatment of multiple myeloma
  1417. RACK1 mRNA translation is regulated via aย Rapamycin-sensitive pathway and coordinated with ribosomal protein synthesis
  1418. Mammalian target ofย Rapamycinย promotes vincristine resistance through multiple mechanisms independent of maintained glycolytic rate
  1419. Bone morphogenetic protein-2โ€“induced transformation involves the activation of mammalian target ofย Rapamycin
  1420. Rapamycinย prolongs susceptibility of responding T cells to tolerance induction by CD8+ veto cells
  1421. Current status of mammalian target ofย Rapamycinย inhibitors in lung cancer
  1422. Rapamycinย inhibits vascular remodeling in an experimental model of allograft vasculopathy and attenuates associated changes in fibrosis-associated gene โ€ฆ
  1423. Rapamycinย and dendritic cells: keep on movinโ€™
  1424. Involvement of c-Jun NH2 terminal kinase and p38MAPK inย Rapamycin-mediatedย inhibitionย of neointimal formation in rat carotid arteries
  1425. Involvement of the VDE homing endonuclease andย Rapamycinย in regulation of the Saccharomyces cerevisiae GSH11 gene encoding the high affinity โ€ฆ
  1426. Immunomodulatory effects of combination of pooled human gammaglobulin andย Rapamycinย on cell proliferation and apoptosis in the mixed lymphocyte reaction
  1427. Six-month intravascular ultrasound follow-up of coronary bifurcation lesions treated withย Rapamycin-eluting stents: technical considerations
  1428. Trace analysis ofย Rapamycinย in human blood by micellar electrokinetic chromatography
  1429. Insulin-like growth factor binding protein-6 and CCI-779, an ester analogue ofย Rapamycin, additively inhibit rhabdomyosarcoma growth
  1430. Differential translation of TOP mRNAs inย Rapamycin-treated human B lymphocytes
  1431. Rapamycinย for androgen-independent prostrate cancer (AIPC)
  1432. Rapamycinย for cardiac transplant rejection and vasculopathy: one stone, two birds?
  1433. Sirolimus and everolimus: inhibitors of mammalian target ofย Rapamycinย in liver transplantation
  1434. Rapamycinย inhibits choroidal neovascularization
  1435. Deletion of HOG1 leads to Osmosensitivity in starvation-induced, but notย Rapamycin-dependent Atg8 degradation and proteolysis: Further evidence for different โ€ฆ
  1436. Structure and function of mammalian target ofย Rapamycinย [J]
  1437. Comparison ofย Rapamycinย and paclitaxel eluting stent in patients with multi-vessel coronary disease
  1438. Retracted:ย Rapamycinย Attenuates Liver Graft Injury in Cirrhotic Recipientโ€”The Significance of Downโ€Regulation of Rhoโ€ROCKโ€VEGF Pathway
  1439. Pharmacokinetics ofย Rapamycin-eluting stents in miniswine coronary model.
  1440. Combination therapy with sirolimus (Rapamycin) and tacrolimus (FK-506) in treatment of refractory minimal change nephropathy, a clinical case report
  1441. Combination of the mammalian target ofย Rapamycinย (mTOR) inhibitor everolimus (E) with the insulin like growth factor-1-receptor (IGF-1-R) inhibitor NVP-AEW-541: A โ€ฆ
  1442. Rapamycinย and chronic lung rejection
  1443. Synergistic suppression of rat neointimal hyperplasia byย Rapamycinย and imatinib mesylate: implications for the prevention of accelerated arteriosclerosis
  1444. An intramolecular ionic hydrogen bond stabilizes a cis amide bond rotamer of a ringโ€openedย Rapamycinโ€degradation product
  1445. The effect of combinedย Rapamycin/cyclosporine on the changes in pro-fibrotic gene expression that occur during the development of allograft vasculopathy in rats โ€ฆ
  1446. Modulation of tissue factor expression byย Rapamycinย and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth โ€ฆ
  1447. Effect ofย Rapamycinย on hepatic osteodystrophy in rats with portasystemic shunting
  1448. Preclinical rationale for therapeutic targeting ofย mTORย by CC-I779 andย Rapamycinย in Hodgkin lymphoma
  1449. Potential role of mammalian target ofย Rapamycinย inhibitors in breast cancer therapy
  1450. Altered centrosomes in ataxiaโ€telangiectasia cells andย Rapamycinโ€treated Chinese hamster cells
  1451. Determination ofย Rapamycin: quantification of the sodiated species by an ion trap mass spectrometer as an alternative to the ammoniated complex analysis by triple โ€ฆ
  1452. Nutritional studies on the growth of theย Rapamycin-producing Streptomyces hygroscopicus
  1453. A novel technique for onโ€capillary preconcentration of anionic compounds applied to the trace analysis ofย Rapamycinย in human blood by capillary electrophoresis
  1454. โ€ฆ of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib in combination with the mammalian target ofย Rapamycinย (mTOR) inhibitor everolimus โ€ฆ
  1455. Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3โ€ฒ-untranslated region of the insulin mRNA (ins-PRS) is inhibited byย Rapamycin
  1456. A phase I trial of gefitinib (ZD1839) plusย Rapamycinย for patients with recurrent malignant glioma
  1457. Clinical use ofย Rapamycinย in renal allograft recipients identifies its relevant toxicity profile and raises unsolved questions: a single-center experience
  1458. Lung toxicity induced byย Rapamycin
  1459. Countervailing effects ofย Rapamycinย (sirolimus) on nuclear factor-ฮบB activities in neointimal and medial smooth muscle cells
  1460. Dose-dependentย inhibitionย of myointimal hyperplasia by orally administeredย Rapamycin
  1461. Association ofย Rapamycinย and co-stimulation blockade using anti-B7 antibodies in renal allotransplantation in baboons
  1462. inhibitionย of growth and metastasis of hepatocellular carcinoma byย Rapamycin: experiment with mice
  1463. Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]ย Rapamycinย and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro
  1464. Rapamycinย inhibits platelet-derived growth factor-induced collagen, but not fibronectin, synthesis in rat mesangial cells
  1465. A combination of anergic cellsโ€™ adoptive transfer andย Rapamycinย therapy prolongs cardiac allograft survival in mice
  1466. Local application ofย Rapamycinย inhibiting restenosis in experimental vein graft
  1467. Negative regulation of interleukin-12 production by aย Rapamycin-sensitive signaling pathway: a brief communication
  1468. Rapamycin-based rescue therapy after chronic rejection in a pediatric liver transplant patient
  1469. Altered trafficking of CD8+ memory T cells after implantation ofย Rapamycin-eluting stents in patients with coronary artery disease
  1470. Rapamycinย at six years can exhibit normal renal function without proteinuria or neoplasia after renal transplantation. A single-center experience
  1471. Expression of placental mammalian target ofย Rapamycinย (mTOR) is altered in relation to fetal growth andย mTORย regulates leucine transport
  1472. Regulation of hepatic insulin-like growth factor-binding protein-1 gene expression by insulin: central role for mammalian target ofย Rapamycinย independent of forkhead โ€ฆ
  1473. Rapamycinโ€“a Potential Mechanistically Targeted Therapeutic for Juvenile Myelomonocytic Leukemia.
  1474. In vivo and in vitro effect of CCI-779 aย Rapamycinย analogue on HNSCC.
  1475. Pathologic assessment of cardiomyocytes in heart transplant recipients treated withย Rapamycinย or cyclosporine
  1476. Pharmacodynamic-guided, modified continuous reassessment method (mCRM)-based, dose finding study ofย Rapamycinย in adult patients with solid tumors
  1477. Pharmacokinetics and safety of ABT-578, a sirolimus (Rapamycin) analogue, after single intravenous bolus injection in healthy male volunteers
  1478. Rapamycinย Inhibits Retinal and Choroidal Neovascularization in Mice
  1479. In Vitro and In Vivo Antileukemic Effects of theย mTOR-Targeting Drugย Rapamycinย in Patients with Imatinib-Resistant CML.
  1480. Dual effects ofย Rapamycinย on immuno-suppression and tumorย inhibition
  1481. Rapamycinย inhibits the pathogenesis of posterior capsule opacification: experimental study on rabbit [J]
  1482. Sphingosine-1-phosphateโ€“induced smooth muscle cell migration involves the mammalian target ofย Rapamycin
  1483. Phase I study of gefitinib andย Rapamycinย in patients with recurrent or progressive glioblastoma (Gbm)
  1484. Rapamycinย has no effect on fibrosis-associated gene expression or extracellular matrix accumulation when administered to animals with established or early โ€ฆ
  1485. Effect ofย Rapamycinย on cytokine profile in kidney transplant recipients treated with triple drug therapy
  1486. Rapamycinย as rescue therapy in a patient supported by biventricular assist device to heart transplantation with consecutive ongoing rejection
  1487. Effect ofย Rapamycinย on Phenotype of Vascular Smooth Muscle Cell and Arterial Intimal Hyperplasia Post Balloon Injury in Rat [J]
  1488. Rapamycinย plays a new role as differentiator of vascular smooth muscle phenotype. Focus on โ€œTheย mTOR/p70 S6K1 pathway regulates vascular smooth muscle โ€ฆ
  1489. โ€ฆ -up of the unrestricted use of the sirolimus-eluting stent compared to the use of a standard bare metal stent as part of theย Rapamycin-Eluting-Stent Evaluated at โ€ฆ
  1490. Observations on quadruple immunosuppression maintenance therapy usingย Rapamycin, low-dose cyclosporine, mycophenolate mofetil, and prednisone following โ€ฆ
  1491. Mode of action of FK506 andย Rapamycin
  1492. Phase I study ofย Rapamycinย (R) in combination with CYP3A4 modifier, ketoconazole (K), in patients with advanced malignancies
  1493. Renal calcium handling afterย Rapamycinย conversion in chronic allograft dysfunction
  1494. Studies towards the synthesis ofย Rapamycin: Regiocontrol in the addition of carbanions to enantiomerically pure epoxides and the formation of a highly substituted โ€ฆ
  1495. Rapamycin.
  1496. Thrombosis caused by activeย Rapamycinย stents
  1497. Effect ofย Rapamycinย and dexamethasone on differentiation and maturation of murine bone marrow-derived dendritic cells
  1498. Comparison ofย Rapamycinย versus FK506 on expression of cytoprotective genes in the rat kidney allografts undergoing chronic allograft nephropathy
  1499. Why inhibitors of mammalian target ofย Rapamycinย will be important in organ transplantation
  1500. Stent release of aย Rapamycinย analogue: tissue pharmacokinetics of rapid versus delayed release
  1501. Rapamycin: from the laboratory to the treatment of patientsโ€™ arteries
  1502. Experimental study on the effects ofย Rapamycinย in prevention of rat corneal allograft rejection
  1503. Rapamycinย overcomes multidrug resistance (MDR) mediated by P-glycoprotein (Pgp), Multidrug Resistance Protein-1 (MRP-1), Breast Cancer Resistance Protein โ€ฆ
  1504. Complete assignments of the 1H and 13C resonances of 40โ€epiโ€(N1โ€tetrazolyl)โ€Rapamycinย and revised 13C assignments forย Rapamycin
  1505. The Combination of theย mTORย Inhibitorย Rapamycinย and Proteasome Inhibitor Bortezomib Is Synergistic In Vitro in Multiple Myeloma.
  1506. Oralย Rapamycinย for the prevention of in-stent restenosis
  1507. Rapamycinย Enhances the Cytotoxicity of Bortezomib and Rituximab on Mantle Cell Lymphoma (MCL) Cell Lines.
  1508. Survivingย Rapamycin
  1509. Lack of effect ofย Rapamycinย in anti-CCP antibody production in a rheumatoid arthritis kidney allograft recipient
  1510. Mammalian target ofย Rapamycinย inhibitors in transplantation: novel immunosuppressive strategies with sirolimus
  1511. Efficacy of Early Use ofย Rapamycinย for Patients after Renal Transplantation and the Complications
  1512. 1139-52 Biolimus A9: a new generationย Rapamycinย analogue inhibits intimal hyperplasia in a porcine model
  1513. Rapamycinย eluting stents
  1514. Mammalian target ofย Rapamycinย (mTOR) as a target in human breast cancer cells that have acquired resistance to aromatase inhibitor letrozole
  1515. Rapamycin: sc-3504
  1516. Investigation ofย Rapamycinย andย Rapamycinย metabolites.
  1517. Inhibitors of mammalian target ofย Rapamycin: mechanism of action explains efficacy and toxicity
  1518. Rapamycinย even when combined with cyclosporine attenuates tumor growth but does not induce regression of established walker sarcomas
  1519. Sirolimus (Rapamycin) reduces the incidence of acute rejection episodes in renal transplantation: An initial experience in Taiwan
  1520. Clinic application ofย Rapamycin-eluting stent for coronary heart disease [J]
  1521. Intravitreal toxicity ofย Rapamycin
  1522. Two-year experience withย Rapamycinย in kidney transplantation
  1523. Safety and efficacy of sirolimus-eluting stent (cypher) in acute myocardial infarction: A substudy of theย Rapamycin-Eluting Stent Evaluation at Rotterdam Cardiology โ€ฆ
  1524. Sirolimus-eluting stents for treatment of in-stent restenosis in the real world: Preliminary results from theย Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology โ€ฆ
  1525. Rapamycinย Combined with Cyclosporine in the Prevention of Acute Renal Allograft Rejection: Randomized Prospective Control Study
  1526. Adverse effects of local or systemic application ofย Rapamycinย for the prevention of neointimal hyperplasia
  1527. Effect of combined regimen ofย Rapamycinย and Cyclosporine on renal transplant recipients [J]
  1528. Short-termย Rapamycinย forย inhibitionย of neointima formation after balloon-mediated aortic injury in rats: is there a window of opportunity for systemic prophylaxis of โ€ฆ
  1529. Pilot study with oralย Rapamycinย in patients undergoing stenting in coronary arteries: Buenos Aires experience (ORAR trial)
  1530. CONTRASTING EFFECTS OF CYCLOSPORIN ANDย Rapamycinย IN DE NOVO GENERATION OF ALLOANTIGEN-STIMULATED REGULATORY T CELLS.
  1531. Combination of theย mTORย inhibitorย Rapamycinย and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17AAG) inhibits proliferation and induces apoptosis โ€ฆ
  1532. Effects ofย Rapamycin-treated HSP60-pulsed dendritic cells on the progression of the atherosclerotic plaque in mice [J]
  1533. Curcumin disrupts the complexes of the mammalian target ofย Rapamycin
  1534. Review onย Rapamycinย as a potential therapeutic agent against neurodegenerative disease
  1535. TOR (target ofย Rapamycin)-mediated regulation of translation
  1536. Comparison of Different Therapies Of CYPHERTM Stent For Patients with Bifurcated Lesion Usingย Rapamycin
  1537. Experimental study of effect ofย Rapamycinย on proliferation of rat aortic smooth muscle cells
  1538. Influence of CTLA4Ig combined withย Rapamycinย on the survival of renal allografts in rats [J]
  1539. Local applied slow-releasingย Rapamycinย inhibits neointima hyperplasia in vein graft
  1540. Rapamycinย PREVENTS INTERSTITIAL FIBROSIS IN RENAL ALLOGRAFTS THROUGH DECREASING ANGIOGENESIS AND INFLAMMATION.
  1541. โ€ฆ Regulatory (CD4+ CD25+ CD127LowFOXP3+) Cells to High Purity by Inhibiting Expansion of CD4+ CD25+ CD127HighFOXP3-Conventional T Cells withย Rapamycinย โ€ฆ
  1542. Rapamycinย impairs the healing of the ureteric anastomosis
  1543. Effects ofย Rapamycinย on the early development of zebrafish (Danio rerio)
  1544. The combination of arsenic trioxide andย Rapamycinย has potent inhibitory effects on acute myeloid leukemia (AML) cells
  1545. avb3-integrin-targeted paramagnetic nanoparticles deliverย Rapamycinย into the vascular wall and inhibit stenosis following balloon injury
  1546. Treatment of lesions with a high risk of stenosis. comparative study in 300 patients ofย Rapamycin-and paclitaxel-eluting polymer-based stents, and bare metal stents
  1547. Rapamycinย Has Biological Activity in a Subset of Patients with Myelodysplastic Syndrome-Results of a Phase I/II Trial.
  1548. Effect of Mycophenolic Acid andย Rapamycinย on the Proliferation of Glomerular Mesangial Cell of Rat
  1549. Regulation of the mammalian target ofย Rapamycinย complex 2 (mTORC2)
  1550. Rapamycinย NOT CYCLOSPORINE INDUCES REGULATORY CD8+ FOXP3+ CELLS.
  1551. Comparison of the effects ofย Rapamycin-eluting stent implantation and coronary artery bypass grafting in treatment of patients with multi-vessel coronary disease
  1552. Glucose-stimulated DNA Synthesis through Mammalian Target ofย Rapamycinย (mTOR) Is Regulated by KATP Channels
  1553. Subretinal sustained delivery ofย Rapamycinย in the rabbit eye
  1554. Constitutive Activation of Akt andย mTORย by Flt3 Internal Tandem Duplications Mediates Myeloid Leukemogenesis and Can Be Inhibited byย Rapamycin.
  1555. Long-term clinical efficiency of endovascular treatment using Cypherย Rapamycin-eluting stents in patients with coronary heart disease
  1556. DOESย Rapamycinย EFFECT WOUND HEALING?
  1557. Successful retransplantation usingย Rapamycinย in a patient with previous calcineurin inhibitor-induced posterior leukoencephalopathy syndrome.
  1558. Rapamycinย inhibits the development of gallbladder adenocarcinoma in BK5. erbB2 transgenic mice
  1559. Rapamycinย disruption ofย mTOR-mLST8-raptor complex inhibits cell motility
  1560. In vitroย Rapamycinย and costimulation generates Th1/Tc1 or Th2/Tc2 central memory effectors: Differential regulation by in vivoย Rapamycinย after allogeneic BMT
  1561. Effect of combination of curcumin andย Rapamycinย on proliferation of rat glomerular mesangial cells
  1562. Signaling by Target ofย Rapamycinย Proteins
  1563. Distinct mechanisms by which low and highย Rapamycinย doses raise plasma triglycerides in guinea pigs
  1564. Everolimus: a classical mammalian target ofย Rapamycinย inhibitor?
  1565. Murine Ultrasonography Confirms Thatย Rapamycinย Is Effective Against Autoimmune Lymphoproliferative Syndrome (ALPS).
  1566. STABILIZATION OF LONG-TERM PEDIATRIC RENAL ALLOGRAFTS WITHย Rapamycin.
  1567. A tissue selectiveย Rapamycinย analog inhibits MDA-MB-231 breast cancer cell-induced osteolytic bone metastases in nude mice
  1568. Rapamycinย throws a master switch.
  1569. Rapamycin-CUSTOMIZED DENDRITIC CELLS ARE RESISTANT TO MATURATION INDUCED BY CD40 LIGATIONโ€”A CONDITION PIVOTAL TO THEIR โ€ฆ
  1570. USE OFย Rapamycinย IN CHILDREN POST LIVER TRANSPLANTATION
  1571. Mammalian Target ofย Rapamycinย inhibitionย Synergistically Increases Cytotoxicity of Vinorelbine in Breast Cancer Cells.
  1572. The role of caspase-3 inย Rapamycin-induced apoptosis of hepatocellular carcinoma BEL-7402 cells
  1573. Enhanced Killing of Chronic Myelogenous Leukemia Cells byย Rapamycinย and Imatinib Is Associated with Differentialย inhibitionย of 4E-BP1 and eIF4E Phosphorylation โ€ฆ
  1574. Rapamycinย Induces Balb/C Murine CD4+CD25+Foxp3+ T Cells Proliferations.
  1575. Effect of locally administeredย Rapamycinย and cyclosporin A on penetrating keratoplasty rejection rat model
  1576. Curcumin inhibits the mammalian target ofย Rapamycin-mediated signaling pathways
  1577. Bone-targetedย Rapamycinย analogs inhibit osteolysis and tumor growth in a PC-3-GFP intratibial bone cancer model in nude mice
  1578. The expression of mammalian target ofย Rapamycinย and its substrates in autogenous vein graft in rats
  1579. Effects ofย Rapamycinย on Notch1/Jagged1 signal pathway and the expression of fibronectin in TGF-ฮฒ, induced rat renal intertitial fibroblasts [J]
  1580. Theย mTORย Inhibitorย Rapamycinย Inhibits Drug Transport in Multidrug Resistant Cell Lines and in Acute Myeloid Leukemia (AML) Cells.
  1581. Effect ofย Rapamycinย on Corneal Neovascularization
  1582. THE EFFECT OFย Rapamycinย ON BILE DUCT HEALING
  1583. Safety and efficacy comparison betweenย Rapamycin-eluting stent with biodegradable polymer or permanent polymer in patients with coronary artery disease
  1584. Rapamycinย added to human CD25+ cell cultures activated through CD3/CD28 enriches for CD4+ CD25+ CD27+ Foxp3+ regulatory T cells
  1585. Effect of Mycophenolic Acid andย Rapamycinย on the Proliferation and Collagen Synthesis of the Vascular Smooth Muscle Cell of Rat
  1586. Two-year experience withย Rapamycinย in kidney transplantation
  1587. Effects ofย Rapamycinย on the function of human dendritic cells
  1588. Effects ofย Rapamycinย on Rho-kinase and p27 mRNA expressions in a porcine coronary intimal proliferation model induced by interleukin-1beta
  1589. IN CONTRAST TO CYCLOSPORIN,ย Rapamycinย SPARES FOXP3+ CD4+ T-CELLS IN VIVO.
  1590. Rapamycinย THERAPY IN PANCREAS ALLOGRAFT RECIPIENTS
  1591. Sustainedย Rapamycinย drug delivery system in prevention of high risk corneal allograft rejection and neovascularization in rabbits
  1592. The role of GSK3ฮฒ inย Rapamycin-mediated cell cycle regulation
  1593. Rapamycinย Treatment Results in GATA
  1594. Possible molecular target therapy withย Rapamycinย in MDS
  1595. Blockingย mTORย byย Rapamycinย reduces HIF-1ฮฑ function in human gastric cancer cells in vitro and inhibits angiogenesis and tumor growth in vivo
  1596. Influence of CTLA4Ig combined withย Rapamycinย on the survival of renal allografts in rats
  1597. Combination therapy of bevacizumab withย Rapamycinย in antitumor activity.
  1598. EVALUATION OF APOPTOSIS IN PERIPHERAL HUMAN LYMPHOCYTES EXPOSED TOย Rapamycin.
  1599. โ€ฆ IN CHRONIC ALLOGRAFT NEPHROPATHY (CAN) FOLLOWING CALCINEURIN INHIBITORS (CNI) WITHDRAWAL AND CONVERSION TOย Rapamycin.
  1600. Application ofย Rapamycinย in the patients with liver injury following renal transplantation: a report of 7 cases
  1601. Establishment of aย Rapamycin-resistant cell line that retains sensitivity to PI3 kinase inhibitors.
  1602. mTORย (mammalian target ofย Rapamycin)ย inhibitionย with RAD001 induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitizes DLBCL cells to โ€ฆ
  1603. A Novel Serum-Stable Micelle System for Controlled Release ofย Rapamycin
  1604. The effects ofย Rapamycinย for the chole-sterol rabbits after balloon injury
  1605. Effect of New Immunosuppressant-Rapamycinย on One-Way Mixed Lymphocyte Culture
  1606. inhibitionย of repopulation is not a determining factor for the radiosensitizing effects ofย Rapamycin
  1607. Antitumor efficacy ofย Rapamycinย derivertive RAD001 in human ovarian cancer
  1608. Dendritic cells,ย Rapamycinย and transplant tolerance
  1609. Troglitazone Exerts a Cell-Dependent Effect on the Extracellular Secretion of VEGF165 Independently from theย Rapamycinย Sensitivity or the Level of eIF4E โ€ฆ
  1610. Rapamycinย inhibited the growth of hepatocellular carcinoma in nude mice
  1611. Rapamycin-Eluting Stents for the Treatment of In-Stent Restenosis
  1612. Effect ofย Rapamycinย on Renal Ischemia Reperfusion Injury
  1613. Mutant type glutathione S-transferase theta 1 gene homologue toย mTORย in myelodysplastic syndrome: possible clinical application ofย Rapamycin
  1614. A RARE CASE OFย Rapamycinย INDUCED SECRETORY DIARRHEA IN A LIVER TRANSPLANT PATIENT: 544
  1615. Clinical application of domesticย Rapamycin-eluting stents in coronary heart disease patients
  1616. The Studies of Antitumor Effect ofย Rapamycinย on Human Hepatocellular Carcinoma BEL-7402 Cells in vitro
  1617. Investigation of the Function and Regulatory Mechanisms of the Mammalian Target ofย Rapamycin
  1618. New progress ofย Rapamycinย in prevention and treatment of chronic allograft nephropathy
  1619. Mammalian Target ofย Rapamycinย (mTOR)
  1620. Rapamycinย treatment during fractionated radiotherapy causes cell death in 3D culture
  1621. 18F-Labeled analog ofย Rapamycinย for PET imaging
  1622. Rapamycin-SENSITTVE SIGNAL TRANSDUCTION PATHWAYS AND THE CONTROL OF ADIPOGENESIS
  1623. Therapeutic effect ofย Rapamycinย in the treatment of malignancies in recipients after kidney transplantation
  1624. Sirolimus (Rapamycin) impairs renal function
  1625. Rapamycinย INHIBITS NK CELL FUNCTION
  1626. โ€ฆ WITH THYMOGLOBULIN/ZENAPAX INDUCTION, TACROLIMUS AND STEROID MAINTENANCE, COMPARINGย Rapamycinย WITH MYCOPHENOLATE MOFETIL โ€ฆ
  1627. Rapamycinย modifies the vascular tone of rat isolated aortas
  1628. Rapamycin-INDUCED PROTEINURIA: INCIDENCE, OUTCOME AND THERAPEUTIC HANDLING.
  1629. Prolonged survival of renal allografts with domesticย Rapamycinย in rats [J]
  1630. โ€ฆ FUNCTIONS OF REGULATORY T CELLS, LEADING, IN CONJUNCTION WITH A BRIEF SUB-THERAPEUTIC COURSE OFย Rapamycin, TO ROBUST, DONOR โ€ฆ
  1631. Clinical Benefits ofย Rapamycin-Eluting Stent Implantation in Patients With Acute Coronary Syndromes
  1632. The role of phosphorylation in the regulation of the mammalian target ofย Rapamycin.
  1633. The clinical effect of homemadeย Rapamycin-eluting stent on acute myocardial infarction
  1634. Regulation of skeletal muscle differentiation by aย Rapamycin-sensitive signaling pathway
  1635. THE MAMMALIAN TARGET OFย Rapamycinย (mTOR) AS A TARGET FOR CANCER CHEMOTHERAPY
  1636. Combination therapy targeting hypoxia inducible factor-ฮฑ (HIF-1 ฮฑ) and Tissue Factor (TF) by theย mTORย inhibitorย Rapamycinย and the histone deacetylase inhibitor โ€ฆ
  1637. Rapamycinย is efficacious against gliomas and acts as an anti-VEGF and anti-invasion agent
  1638. DIFFERENT FUNCTIONAL, HISTOLOGICAL AND INMUNOHISTOCHEMICAL PATTERNS INDUCED BY THE ASSOCIATION OFย Rapamycinย WITH FK506 OR โ€ฆ
  1639. Orally Administeredย Rapamycinย Can Inhibit Myointimal Hyperplasia: Should It Be Used?
  1640. Effects ofย Rapamycin-eluted stent on platelet function in patients with coronary heart disease
  1641. Regulation of the GATA-type transcription factor Gln3p by the target ofย Rapamycinย protein (TOR).
  1642. Combination ofย Rapamycinย and somatostatin analogues for the treatment of nonfunctioning pituitary tumors
  1643. The experimental study on the effects ofย Rapamycinย and statin on chronic transplant vasculopathy
  1644. Rapamycinย targets Cyclin/Cdk/p21/PCNA complexes and Cyclin D1 reversesย Rapamycinย action by stabilizing these complexes
  1645. Rapamycinย conversion for immunosuppressive therapy in the setting of renal insufficiency in patients with heart transplantation: pilot observations
  1646. Inhibitory Effect ofย Rapamycinย on Corneal Neovascularization induced by Angiogenin in Rabbits
  1647. NURSING IMPLICATIONS REGARDING THE MANAGEMENT OF SIDE EFFECTS IN A PHASE I STUDY USING GEFITINIB WITHย Rapamycin.
  1648. Clinical Contrast Investigation ofย Rapamycinย Eluting Stent between Chinese Making and Imported
  1649. The role of mammalian target ofย Rapamycinย (mTOR) in a rat model of autoimmune myocarditis
  1650. Effect ofย Rapamycinย on Mouse Chronic Lymphocytic Leukemia and the Development of Nonhematopoietic Malignancies in Em-TCL1 Transgenic Mice
  1651. Overview of Therapeutic Potential ofย Rapamycinย for Coronary Artery Diseases in the Era of the Drug-Eluting Stent
  1652. Rapamycin-Sensitive Signal Transduction Pathways and the Control of Adipogenesis
  1653. Rapamycinย for Cardiac Transplant Rejection and Vasculopathy
  1654. Rapamycinย synergistically enhances the cytotoxicity of paclitaxel in breast cancer cells
  1655. Oralย Rapamycinย attenuates progression of atherosclerotic plaque in ApoE knockout mice
  1656. Clinical Research ofย Rapamycin-Eluting Stent in Treatment of Multi-Vessel Coronary Disease
  1657. Rapamycinย inhibits expression of minichromosome maintenance proteins in vascular smooth muscle cells
  1658. Biocompatibility ofย Rapamycin-Batroxobin Eluting Stent in Porcine Coronary Artery
  1659. Effect ofย Rapamycinย on anti-HLA donor antibody formation in patients with transplant coronary artery disease
  1660. Combination of theย mTORย Inhibitorย Rapamycinย and Revlimidโ„ข(CC-5013) Has Synergistic Activity in Multiple Myeloma (MM).
  1661. Characterization of the FKBPยทRapamycinยทFRB Ternary Complex โ€‰[J. Am. Chem. Soc. 2005, 127, 4715โˆ’4721].
  1662. Is there a role for oralย Rapamycinย in restenosis prevention after bare-metal stent implantation?
  1663. Isolation and Genetic Analysis ofย Rapamycin-sensitive mutants in Aspergillus nidulans.
  1664. Overexpression of the Bad mutant (S112A) partially disrupts the ability of IGF-I to protect cells fromย Rapamycin-induced apoptosis
  1665. One year effect ofย Rapamycinย eluting stent in patients with coronary heart disease
  1666. The role of mammalian target ofย Rapamycinย (mTOR) in insulin resistance
  1667. Rapamycinย AND SANGLIFEHRIN A CAN INHIBIT INTERLEUKIN-18 PRODUCTION FROM DENDRITIC CELLS IN VITRO AND IN VIVO.
  1668. MRI detection ofย Rapamycinย and AP-Cav therapeutic rescue from endothelial over expression of Akt in transgenic mice
  1669. SENSITIVITY OF HUMAN METASTATIC MELANOMA CELLS TO THE ESTER ANALOG OFย Rapamycin, CCI-779
  1670. Synergistic growthย inhibitionย by Iressa andย Rapamycinย in Renal Cell Carcinoma (RCC) with wild-type VHL
  1671. Six-month results of a biodegradable polymer andย Rapamycin-coating stent for coronary artery disease
  1672. Theย mTORย inhibitor,ย Rapamycin, inhibits growth of Ewingโ€™s sarcoma in vitro and in vivo
  1673. EEEICACY AND SAFETY OFย Rapamycin-BASED IMMUNOSUPPRESSION REGIMEN WITH OR WITHOUT CSA IN RENAL TRANSPLANTATION: A SYSTEMATIC โ€ฆ
  1674. Rapamycinย Inhibits Rabbit Corneal Neovascularization Induced by Angiogenin
  1675. Preclinical analysis ofย Rapamycinย plus EGFR or MEK1/2 inhibitors in renal cell carcinoma (RCC)
  1676. Effect ofย Rapamycinย (RPM) on interleukin-10 gene expression in rats with postburn Staphylococcus aureus sepsis
  1677. Effect ofย Rapamycinย on mouse CLL and development of non-hematopoietic malignancies in Eฮผ-TCL1 transgenic mice
  1678. Effect of isoflavones alone and in combination withย Rapamycinย onย mTORย pathway in human glioblastoma cells (U87).
  1679. Rapamycinย INHIBITS THE SPONTANEOUS FORMATION OF DE NOVO CANCER IN P53 KNOCKOUT MICE.
  1680. Urokinase-induced smooth muscle cell migration involves the mammalian target ofย Rapamycin
  1681. Importance of mammalian target ofย Rapamycinย inhibitors in the prevention of cardiac allograft vasculopathy
  1682. Rapamycinย enhances the number and function of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro
  1683. Clinical contrast investigation ofย Rapamycinย eluting stent between Chinese making and imported in the treatment of coronary artery disease
  1684. Rapamycinย inhibits activation of STAT3 in renal tissue of IgA nephropathy rats
  1685. Theย mTORย inhibitorย Rapamycinย inhibits proadhesive activity of arterial intimal smooth muscle cells
  1686. Identification of a highly effectiveย Rapamycinย schedule that markedly reduces the size, multiplicity and phenotypic progression of tobacco carcinogen-induced murine โ€ฆ
  1687. Mammals Target Protein ofย Rapamycinย (mTOR) Expression in Adult Acute Myeloid Leukemia Patients
  1688. A Randomized Comparison Between Paclitaxel-Eluting Stents andย Rapamycin-Eluting Stents for Patients With Coronary Artery Diseases
  1689. Silencingย mTORย signal by small interfering RNA enhancesย Rapamycin-induced autophagy in malignant glioma cells.
  1690. CYCLOSPORINE ANDย Rapamycinย ACT IN A SYNERGISTIC AND DOSE-DEPENDENT MANNER IN A MODEL OF IMMUNOSUPPRESSANT-INDUCED KIDNEY โ€ฆ
  1691. The role of the mammalian target ofย Rapamycinย (mTOR) in long term potentiation
  1692. Nursing intervention of chronic renal diseases patients orally takingย Rapamycinย after underwent kidney transplantation [J]
  1693. The effect ofย Rapamycinย after cyclosporin dose reduction on chronic allograft nephropathy
  1694. The Saccharomyces Cerevisiae Phosphatase Activator YPTPA1/RRD1 is Required to Modulate Gene Expression in Response toย Rapamycinย Exposure
  1695. COMBINATION OFย Rapamycinย PLUS MUTANT TGF-b/Fc TO INDUCE IMMUNE TOLERANCE.
  1696. Effect of Akt (PKB) on the activity of mammalian target ofย Rapamycinย (mTOR)
  1697. Effect ofย Rapamycinย Eluting Stent on Level of C-reactive Protein in Patients with Acute Coronary Syndrome After Angioplasty [J]
  1698. PI3K andย mTORย signalling pathways: perspectives forย Rapamycinย and its derivatives as antineoplastic targeted therapies
  1699. Effectiveness and safety ofย Rapamycin-based immunosuppression regimens on preserving or withdrawing CsA in renal transplantation: a systematic review
  1700. The modulation of neointimal proliferation and p27 kip expression after implantingย Rapamycin-eluting stents in the porcine coronary model
  1701. Different releasedย Rapamycinย eluting stents to reduce in-stent neointimal hyperplasia in a porcine coronary model
  1702. CHIMERISM PLAYS AN ACTIVE ROLE IN TRANSPLANTATION TOLERANCE INDUCED BY ALS,ย Rapamycinย AND DONOR BONE MARROW INFUSION
  1703. Effect of Biodegradableย Rapamycin-Eluting Stent on Neointimal Proliferation in Porcine Coronary Artery Model
  1704. Rapamycinย INHIBITS IL-10 INDUCTION BY LATENT MEMBRANE PROTEIN 1 OF EPSTEIN BARR VIRUS.
  1705. Editorial [Hot Topic: Mammalian Target ofย Rapamycinย as a Therapeutic Target in Leukemia (Executive Editors: Francis J. Giles/Maher Albitar)]
  1706. A Gene Expression Connectivity Map Identifiesย Rapamycinย as a Glucocorticoid Resistance Reversal Agent in Lymphoblastic Leukemia.
  1707. Rapamycin-sensitive TOR signaling regulates intestinal growth and morphogenesis in zebrafish
  1708. TARGET OFย Rapamycinย (TOR) MEDIATES THE ENDODERM-INTESTINE TRANSITION IN ZEBRAFISH: 68
  1709. Lactic-co-glycolic acid polymer withย Rapamycinย coated stent reduces neo-intimal formation in a porcine coronary model
  1710. The mammalian target ofย Rapamycinย controls cell motility through its effectors S6K1 and 4E-BP1
  1711. SAFETY AND EFFICACY OF A STEROID-FREE REDUCED-DOSE NEORAL/Rapamycinย MAINTENANCE IMMUNOSUPPRESSION IN RENAL TRANSPLANTATION โ€ฆ
  1712. inhibitionย ofย mTORย signaling withย Rapamycinย attenuates renal hypertrophy in the early diabetic mice
  1713. Combinations of Cytotoxic Drugs, Ionizing Radiation, and Mammalian Target ofย Rapamycinย (mTOR) Inhibitors
  1714. Effects of stent-based delivery ofย Rapamycinย and methotrexate on neointimal formation in a porcine coronary model
  1715. Rapamycinย MANIPULATION OF HOST-DERIVED, ALLOANTIGEN-PULSED DENDRITIC CELLS PLUS POSTOPERATIVEย Rapamycin, BUT NOT FK506 โ€ฆ
  1716. Ex Vivoย Rapamycinย Generates Th2 Cells with Enhanced Mitochondrial Function and Reduced Apoptosis Via Intrinsic and Extrinsic Pathways.
  1717. combination with the immunosuppressive drugย Rapamycin, seems to forestall rejection in mice. Transferring this protocol to the human clinic should be fairly straight โ€ฆ
  1718. Rapamycin-generated CD4+, Th2 cells modulate graft-versus-host reaction via an IL-4 dependent mechanism
  1719. The assessment of human islets for transplantation and the effect of the immunosuppressantย Rapamycinย on MIN-6 cells, rat and human islets
  1720. 549: The Effect ofย Rapamycinย Immunosuppression on Native Polycystic Kidney Volumes in Renal Transplant Patients
  1721. Calcineurin inhibitors but notย Rapamycinย abrogate activation of the immunomodulatory enzyme indoleamine 2, 3-dioxygenase.
  1722. Translational control of gene expression in rat liver in relation to mammalian target ofย Rapamycinย signaling
  1723. Rapamycinย Protects Allografts From Rejection While Simultaneously Attacking Tumors in Immunosuppressed Mice
  1724. Rapamycinย and IL-10 induce Ag-specific T regulatory type 1 cells (Tr1) and b-islet allograft tolerance in diabetic mice
  1725. In Vitro and in Vivo Cyclosporine-Induced Tumor Angiogenesis and Tumor Growth Are Blocked By Simultaneous Application ofย Rapamycin
  1726. Rapamycinย INHIBITS EPSTEIN BARR VIRUS+ B CELL LYMPHOMA THROUGH MODULATION OF CELL CYCLE PROTEIN EXPRESSION.
  1727. Newly identified kit ITD in childhood AML induces ligand independent growth and is responsive to a synergistic effect of imatinib andย Rapamycin
  1728. Effects of the immunomodulatory drugs tacrolimus,ย Rapamycinย and cilomilast on dendritic cell function in a model of allergic contact dermatitis
  1729. Rapamycinย exerts an anti-inflammatory action in vitro and in vivo by inducing monocyte apoptosis and modulating cytokine/chemokines secretion
  1730. Site specific systemic delivery ofย Rapamycinย with perfluorobutane gas microbubble carrier reduced neointimal formation in the porcine coronary restenosis model
  1731. Rapamycinย sensitizes tumor cells to chemotherapy-induced apoptosis and induces cell cycle arrest in ALK+ anaplastic large cell lymphoma.
  1732. Sustainedย Rapamycinย Drug Delivery System for Prevention of High Risk Corneal Allograft Rejection and Neovascularization in Rabbits
  1733. Everolimus Is Comparably Effective toย Rapamycinย Acting Synergistically with Imatinib in the Treatment of Constitutively Active Mutations of the Juxtamembrane โ€ฆ
  1734. Unrestricted Utilization of Sirolimus-Eluting Stents in the โ€œReal Worldโ€: Theย Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital โ€ฆ
  1735. Serotonin-mediated activation ofย Rapamycin-sensitive S6 kinase-S6 ribosomal protein signal transduction pathway in synaptosomes.
  1736. Rapamycinย INHIBITS EPSTEIN BARR VIRUS+ B CELL LYMPHOMA PROLIFERATION THROUGH MODULATION OF CELL CYCLE PROTEIN EXPRESSION.
  1737. Effects ofย Rapamycinย Eluting Stents on Blood Tissue Factor and Tissue Factor Pathway Inhibitor in Patients With Acute Coronary Syndromes
  1738. DONOR SPECIFIC TRANSFUSION COMBINED WITHย Rapamycinย PROLONGED THE CARDIAC GRAFT SURVIVAL IN MICE.
  1739. Activity of panitumumab plusย Rapamycinย against wild type (WT) and mutant epidermal growth factor receptor (EGFr)-expressing NSCLC xenografts
  1740. TACROLIMUS DECREASES, CYCLOSPORINE INCREASES, ANDย Rapamycinย HAS NO EFFECT ON PROFIBROTIC GENE MRNA EXPRESSION IN RENAL โ€ฆ
  1741. Rapamycinย Generated Murine Th2/Tc2 Cells Potently Abrogate Fully MHC-Mismatched Hematopoietic Stem Cell (HSC) Graft Rejection.
  1742. 548:ย inhibitionย of theย mTORย Pathway byย Rapamycinย Reverses Renal Cystogenesis in Polycystic Kidney Disease Models
  1743. Theย mTORย inhibitorย Rapamycinย inhibits p27 protein degradation by downregulating the expression of its ubiquitin ligase Skp2 in breast cancer
  1744. Induction of apoptosis in Ewingโ€™s Sarcoma cells by simultaneous treatment with antisense oligodeoxynucleotides (AS-ODNs) to the EWS/FLI-1 gene andย Rapamycin
  1745. Construction of eukaryotic expression vector of mammalian target ofย Rapamycinย antisense RNA and its expression in vascular smooth muscle cell
  1746. INFLUENCE OF IMMUNOPHILLINS INHIBITORSโ€“CYCLOSPORINE-A, TACROLIMUS ANDย Rapamycinโ€“ON INSULIN SECRETION IN HEART TRANSPLANT โ€ฆ
  1747. Targeting the ICOS-B7h Costimulatory Pathway Synergizes withย Rapamycinย to Regulate Alloresponses in Islet Transplantation: 0102
  1748. Short and long-term therapeutic effects ofย Rapamycin-eluting stent and paclitaxel-eluting stent in treatment of coronary disease with complicated lesions
  1749. The Immunomodulatory Agentย Rapamycinย Potentiates the Antiviral Activity of the Fusion Inhibitor T20 Against R5 Strains of HIV-1
  1750. Binding ofย mTORย (Mammalian Target ofย Rapamycin) to the Raptor-eIF4E-4EBP1 complex changes during myogenic differentiation.
  1751. COMBINATION OFย Rapamycinย AND ANTI-LFA-1 PREVENTS REJECTION OF RAT ISLET XENOGRAFTS.: 042
  1752. Hypoxia andย Rapamycinย induced changes to the cell cycle of multicellular spheroids and human tumour xenografts leading to potential therapeutic advantage
  1753. 1853: A Propsective Study With Thymoglobulin/Daclizumab Induction, Tacrolimus and Steroid Maintenance, Comparingย Rapamycinย With Mycophenolate Mofetil as โ€ฆ
  1754. Anti-angiogenic and immunomodulatory effects ofย Rapamycinย on pancreatic islet endothelial cells: relevance for islets engraftment after transplantation
  1755. A comparison study on FTY720, 40-O-(2-hydroxyethyl)-Rapamycinย and cyclosporine to prolong the survival of mouse heart allograft
  1756. Role of p53 in TRAIL-induced apoptosis in glioblastoma multiforme and modulation by taxol,ย Rapamycinย or temozolomide
  1757. DIFFERENTIAL EFFECT OF CALCINEURIN INHIBITORS, ANTI-CD25 ANTIBODIES ANDย Rapamycinย ON THE INDUCTION OF FOXP3 IN HUMAN T-CELLS IN VIVO โ€ฆ
  1758. โ€ฆ mechanisms regulating proliferation, antigen responsiveness, and differentiation of CD4โบ T lymphocytes: a central role for the mammalian target ofย Rapamycinย (mTORย โ€ฆ
  1759. Overexpression of a critical target ofย Rapamycin, translation regulatory protein 4E-BP1, is largely restricted to locally advanced breast and prostate cancers and is lost โ€ฆ
  1760. Receptor activator of NF-kB (RANK) and its ligand RANK-L coincide with expression ofย Rapamycinย receptor FKBP12 in neointimal dendritic cells
  1761. The PI3K inhibitor LY294002 and theย mTORย inhibitorย Rapamycinย sensitize melanoma cells to cisplatin and temozolomide
  1762. Rapamycinย and Anti-LFA-1 Monoclonal Antibody Prevent the Rejection of Rat Islet Xenografts and Induce Tolerance in BALB/c Mice
  1763. Glucagon Represses Insulin Signaling through Mammalian Target ofย Rapamycinย (mTOR) in Perfused Rat Liver
  1764. MYCOPHENOLATE MOFETIL (MMF)/Rapamycinย (RAPA) COMPARED TO OTHER COMMON IMMUNOSUPPRESSIVE REGIMENS IN KIDNEY โ€ฆ
  1765. Ras Homologue Enrich in Brain (Rheb) Enhances Hypertrophic Response via the Mammalian Target ofย Rapamycinย (mTOR)/p70S6K Pathway
  1766. โ€ฆ OF HUMAN BONE MARROW DERIVED MESENCHYMAL PROGENITORSโ€”A SIGNAL TRANSDUCTION BASE FOR PLEIOTROPY OFย Rapamycinย DERIVATES.
  1767. grammed autophagy in the fat body during the final larval stage. TOR (target ofย Rapamycin) kinases, the central components of a conserved nutri-ent-sensing โ€ฆ
  1768. ANTI-CD25 MAB, ANTI-IL2 MAB AND IL2 BLOCK TOLERANCE INDUCTION THROUGH ANTI-CD154 MAB ANDย Rapamycinย IN XENOGENEIC ISLET โ€ฆ
  1769. Schedule-dependent activity of combined epidermal growth factor receptor (EGFR) and mammalian target ofย Rapamycinย (mTOR) targeting in PTEN negative breast โ€ฆ
  1770. Differential effects of the immunosuppressive agents cyclosporine A,ย Rapamycinย and FK-506 on drug transport by the ATP-binding cassette (ABC) proteins P โ€ฆ
  1771. Amino acid transporter ASCT2 expression regulates mammalian Targetโ€ofโ€Rapamycinย (mTOR) growth and survival signaling in human hepatoma cells
  1772. โ€ฆ WITHDRAWAL (PW) TRIAL IN KIDNEY TRANSPLANT PATIENTS TREATED WITH MYCOPHENOLATE SODIUM (MS) COMPARINGย Rapamycinยฎ VS. C2 DOSED โ€ฆ
  1773. Rapamycinย AND ANTI-LFA-1 THERAPY MEDIATE ISLET GRAFT SPECIFIC TOLERANCE IN CONCORDANT XENOGENEIC ISLET TRANSPLANTATION.
  1774. PHARMACOKINETICS OF ONCE A DAY DOSE OF CYCLOSPORINE IN COMBINATION WITHย Rapamycinย AND PREDNISONE IN RENAL TRANSPLANTATION IN โ€ฆ
  1775. ROLE OF THE MAMMALIAN TARGET OFย Rapamycinย IN THE REGULATION OF SKELETAL MUSCLE PROTEIN SYNTHESIS AND eIF2B EPSILON mRNA โ€ฆ
  1776. IGF-1 rescuesย Rapamycin-induced cell growthย inhibition
  1777. CONCOMITANT USE OF CYCLOSPORINE-A (CyA) ANDย Rapamycinย (RAPA) WITH A CONSECUTIVE CONVERSION TO RAPA AND MYCOPHENOLATE MOFETIL โ€ฆ
  1778. UP-02.50: A study of the role of insulin like growth factor 1 (IGF1) andย Rapamycinย sensitive signaling in an androgen independent prostate cancer cell line
  1779. โ€ฆ GROWTH FACTOR RECEPTOR (EGFR) INHIBITOR GEFITINIB AND THE MAMMALIAN TARGET OFย Rapamycinย (mTOR) INHIBITOR EVEROLIMUS
  1780. QUADRUPLE IMMUNOSUPPERSSIVE MAINTENANCE THERAPY USINGย Rapamycin, LOW-DOSE CYCLOSPORINE, MYCOPHENOLATE MOFETIL, AND โ€ฆ
  1781. PJ-138 New Sesquiterpene Lactone Compared withย Rapamycinย Inhibits Migration Rather than Proliferation in Rat Vascular Smooth Muscle Cells
  1782. Combination therapy targeting the EWS/FLI-1 oncogene with antisense oligonucleotides andย Rapamycinย induces apoptosis of Ewingโ€™s sarcoma cells in vitro and โ€ฆ
  1783. โ€ฆ 3-kinase; RTK, receptor tyrosine kinase; S6K, ribosomal S6 kinase; TNF-ฮฑ, tumor necrosis factor ฮฑ; TOR, target ofย Rapamycin; TSC, tuberous sclerosis complex โ€ฆ
  1784. LONG-TERM LIMB ALLOGRAFT SURVIVAL USING A SHORT COURSE OF ANTI-CD45RB MONOCLONAL ANTIBODY, LF15-0195 ANDย Rapamycinย IN A MOUSE โ€ฆ
  1785. A role for HO-1 in the renal function impairment inย Rapamycin-treated animals submitted to ischemic and reperfusion injury (IRI).
  1786. Bone Morphogenetic Protein 2 (BMP-2) promotes foci formation through the activation of mammalian target ofย Rapamycin
  1787. GSK-3/Rb12 Pathway as a Novel Target ofย Rapamycinย in Prostate Cancer
  1788. PIIโ€9: Improved platelet function in renal transplant patients after conversion from azathioprin toย Rapamycin
  1789. Drug-eluting stents, 5-sirolimus stents and oralย Rapamycin
  1790. Autophagic Cell Death in Leukemia Cells Regulated by Ceramide and Sphingosine-1-Phosphate through Mammalian Target ofย Rapamycin.
  1791. 4-(N-Methyl-N-nitrosamino)-1 (3-pyridyl)-1-butanone (NNK) Restored the Cap-dependent Protein Translation Blocked byย Rapamycin
  1792. The Saccharomyces cerevisiae GATA-factor activatorsโ€™ response to the 14-3-3 proteins, nutrient limitation,ย Rapamycinย and MSX treatment, and cis-acting โ€ฆ
  1793. 1871:ย Rapamycinย and Ischemia on Experimental Transplant Arteriosclerosis
  1794. 1158-52 Proteomic profiling of restenotic lesions unveils increased expression of structural proteins that are inhibited by intramural delivery ofย Rapamycin
  1795. โ€ฆ and Activator of Transcription-1 (STAT1)-dependent Gene Transcription by Lipopolysaccharide and InterferonฮณIs Regulated by Mammalian Target ofย Rapamycin
  1796. P-205 STUDIES ON FUNGAL SECONDARY METABOLISM USINGย Rapamycinย AS A MOLECULAR PROBE
  1797. Sphingosine-1-phosphateโ€“induced smooth muscle cell migration involves the mammalian target ofย Rapamycin
  1798. Rapamycin: something old, something new, sometimes borrowed and now renewed
  1799. Rapamycinย andย mTORย kinase inhibitors
  1800. Rapamycinย is a neuroprotective treatment for traumatic brain injury
  1801. Rapamycinย prevents epilepsy in a mouse model of tuberous sclerosis complex
  1802. Rapamycinย prevents early steps of the development of diabetic nephropathy in rats
  1803. Rapamycinย induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism
  1804. Targeting mammalian target ofย Rapamycinย (mTOR) for health and diseases
  1805. A role for mammalian target ofย Rapamycinย in regulating T cell activation versus anergy
  1806. A rational mechanism for combination treatment of Huntingtonโ€™s disease using lithium andย Rapamycin
  1807. Antitumor activity ofย Rapamycinย in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
  1808. Rapamycinย differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
  1809. Theย Rapamycin-binding domain of the protein kinase mammalian target ofย Rapamycinย is a destabilizing domain
  1810. The mammalian target ofย Rapamycinย signaling pathway: twists and turns in the road to cancer therapy
  1811. The mammalian target ofย Rapamycinย complex 2 controls folding and stability of Akt and protein kinase C
  1812. Rapamycin, a specific inhibitor of the mammalian target ofย Rapamycin, suppresses lymphangiogenesis and lymphatic metastasis
  1813. Neuroprotection ofย Rapamycinย in lactacystin-induced neurodegeneration via autophagy enhancement
  1814. inhibitionย of the mammalian target ofย Rapamycinย impedes lymphangiogenesis
  1815. Contrasting Effects of Cyclosporine andย Rapamycinย in De Novo Generation of Alloantigenโ€Specific Regulatory T Cells
  1816. Metformin inhibits mammalian target ofย Rapamycinโ€“dependent translation initiation in breast cancer cells
  1817. Roles of rapH and rapG in positive regulation ofย Rapamycinย biosynthesis in Streptomyces hygroscopicus
  1818. Temsirolimus, an inhibitor of mammalian target ofย Rapamycin
  1819. The Mammalian target ofย Rapamycinย pathway regulates nutrient-sensitive glucose uptake in man
  1820. Silencing mammalian target ofย Rapamycinย signaling by small interfering RNA enhancesย Rapamycin-induced autophagy in malignant glioma cells
  1821. Selective survival of naturally occurring human CD4+ CD25+ Foxp3+ regulatory T cells cultured withย Rapamycin
  1822. Mammalian target ofย Rapamycinย is activated in human gastric cancer and serves as a target for therapy in an experimental model
  1823. Rapamycinย inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells
  1824. mTORย inhibitionย byย Rapamycinย prevents ฮฒ-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes
  1825. The mammalian target ofย Rapamycin-signaling pathway in regulating metabolism and growth,
  1826. Rapamycinย derivatives reduceย mTORC2 signaling and inhibit AKT activation in AML
  1827. Hypoxia-inducible factor 1ฮฑ is regulated by the mammalian target ofย Rapamycinย (mTOR) via anย mTORย signaling motif
  1828. Rapamycinย inhibits the growth and muscle-sparing effects of clenbuterol
  1829. Rapamycinย treatment for a child with germline PTEN mutation
  1830. Effect ofย Rapamycinย alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma
  1831. PRAS40 is a target for mammalian target ofย Rapamycinย complex 1 and is required for signaling downstream of this complex
  1832. Use of sirolimus (Rapamycin) to treat refractory Crohnโ€™s disease
  1833. Rapamycinย affects early fracture healing in mice
  1834. Mammalian target ofย Rapamycinย inhibitionย as a therapeutic strategy in the management of urologic malignancies
  1835. The role of hypothalamic mammalian target ofย Rapamycinย complex 1 signaling in diet-induced obesity
  1836. Re-evaluating the roles of proposed modulators of mammalian target ofย Rapamycinย complex 1 (mTORC1) signaling
  1837. Mammalian target ofย Rapamycinย inhibitor dyslipidemia in kidney transplant recipients
  1838. Dose-and schedule-dependentย inhibitionย of the mammalian target ofย Rapamycinย pathway with everolimus: a phase I tumor pharmacodynamic study in patients with โ€ฆ
  1839. Rapamycinย inhibits F-actin reorganization and phosphorylation of focal adhesion proteins
  1840. Rapamycinย prevents thyroid hormone-induced cardiac hypertrophy
  1841. Mammalian target ofย Rapamycinย (mTOR) orchestrates the defense program of innate immune cells
  1842. Rapamycinย modulates the eNOS vs. shear stress relationship
  1843. Rapamycinย inhibits trypanosome cell growth by preventing TOR complex 2 formation
  1844. The mammalian target ofย Rapamycinย regulates lipid metabolism in primary cultures of rat hepatocytes
  1845. Gonadal impact of target ofย Rapamycinย inhibitors (sirolimus and everolimus) in male patients: an overview
  1846. Phase I trial of the novel mammalian target ofย Rapamycinย inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to โ€ฆ
  1847. Randomized trial of threeย Rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis
  1848. Toll-like receptorโ€“mediated induction of type I interferon in plasmacytoid dendritic cells requires theย Rapamycin-sensitive PI (3) K-mTOR-p70S6K pathway
  1849. The role of mammalian target ofย Rapamycinย inhibitors in the treatment of advanced renal cancer
  1850. Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF andย Rapamycin
  1851. Mammalian target ofย Rapamycinย as a therapeutic target in oncology
  1852. Pilot study ofย Rapamycinย in patients with hormone-refractory prostate cancer
  1853. Regulation of androgen receptor transcriptional activity byย Rapamycinย in prostate cancer cell proliferation and survival
  1854. Changes in tumor metabolism as readout for Mammalian target ofย Rapamycinย kinaseย inhibitionย byย Rapamycinย in glioblastoma
  1855. Response of a neuronal model of tuberous sclerosis to mammalian target ofย Rapamycinย (mTOR) inhibitors: effects onย mTORC1 and Akt signaling lead to improved โ€ฆ
  1856. inhibitionย of Mammalian target ofย Rapamycinย byย Rapamycinย causes the regression of carcinogen-induced skin tumor lesions
  1857. Chemoprevention and treatment of experimental Cowdenโ€™s disease byย mTORย inhibitionย withย Rapamycin
  1858. Antitumor activity ofย Rapamycinย and octreotide as single agents or in combination in neuroendocrine tumors
  1859. In human endothelial cellsย Rapamycinย causesย mTORC2ย inhibitionย and impairs cell viability and function
  1860. Mammalian target ofย Rapamycinย and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells
  1861. Mammalian target ofย Rapamycinย pathway activity in hepatocellular carcinomas of patients undergoing liver transplantation
  1862. Differential impact of mammalian target ofย Rapamycinย inhibitionย on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells
  1863. Rapamycinย is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling
  1864. Dissecting the Akt/mammalian target ofย Rapamycinย signaling network: emerging results from the head and neck cancer tissue array initiative
  1865. Rapamycinย impairs in vivo proliferation of islet beta-cells
  1866. Total synthesis ofย Rapamycin
  1867. Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration byย Rapamycin
  1868. Systemicย inhibitionย of mammalian target ofย Rapamycinย inhibits fear memory reconsolidation
  1869. The Target ofย Rapamycinย pathway antagonizes pha-4/FoxA to control development and aging
  1870. Rapamycinย monotherapy in patients with type 1 diabetes modifies CD4+ CD25+ FOXP3+ regulatory T-cells
  1871. Mammalian target ofย Rapamycinย in the human placenta regulates leucine transport and is downโ€regulated in restricted fetal growth
  1872. Theย mTORย inhibitorย Rapamycinย significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
  1873. Rapamycinย inhibits osteoblast proliferation and differentiation in MC3T3โ€E1 cells and primary mouse bone marrow stromal cells
  1874. Antidepressive-like effects ofย Rapamycinย in animal models: Implications forย mTORย inhibitionย as a new target for treatment of affective disorders
  1875. Alterations in mammalian target ofย Rapamycinย signaling pathways after traumatic brain injury
  1876. Regulatory effects of mammalian target ofย Rapamycin-activated pathways in type I and II interferon signaling
  1877. Preparation ofย Rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation
  1878. Bnip3 mediates the hypoxia-inducedย inhibitionย on mammalian target ofย Rapamycinย by interacting with Rheb
  1879. Sirolimus (Rapamycin): from the soil of Easter Island to a bright future
  1880. Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, andย Rapamycin
  1881. AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target ofย Rapamycin/p70S6K1 pathway
  1882. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ โ€ฆ
  1883. Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells
  1884. Dietary energy balance modulates signaling through the Akt/mammalian target ofย Rapamycinย pathways in multiple epithelial tissues
  1885. Rapamycinย attenuates the severity of established nephritis in lupus-prone NZB/WF1 mice
  1886. Isolation of hyperactive mutants of mammalian target ofย Rapamycin
  1887. P-Rex1 links mammalian target ofย Rapamycinย signaling to Rac activation and cell migration
  1888. Rapamycinย inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis
  1889. Bevacizumab andย Rapamycinย induce growth suppression in mouse models of hepatocellular carcinoma
  1890. Phosphoprotein pathway mapping: Akt/mammalian target ofย Rapamycinย activation is negatively associated with childhood rhabdomyosarcoma survival
  1891. Delivery ofย Rapamycinย by PLGA nanoparticles enhances its suppressive activity on dendritic cells
  1892. Rapamycinย regulates the phosphorylation of rictor
  1893. Inhibitors of mammalian target ofย Rapamycinย downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo
  1894. Distinct signaling mechanisms activate the target ofย Rapamycinย in response to different Bโ€cell stimuli
  1895. Therapeutic effect ofย Rapamycinย on gallbladder cancer in a transgenic mouse model
  1896. Rapamycinย sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common โ€ฆ
  1897. Activated mammalian target ofย Rapamycinย is an adverse prognostic factor in patients with biliary tract adenocarcinoma
  1898. Expression of an activated mammalian target ofย Rapamycinย in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy
  1899. The effect of immunosuppressive drugย Rapamycinย on regulatory CD4+ CD25+ Foxp3+ T cells in mice
  1900. Impact ofย Rapamycinย on liver regeneration
  1901. Curcumin inhibits Akt/mammalian target ofย Rapamycinย signaling through protein phosphatase-dependent mechanism
  1902. Combination ofย Rapamycinย and IL-2 increases de novo induction of human CD4+ CD25+ FOXP3+ T cells
  1903. Translational control of c-MYC byย Rapamycinย promotes terminal myeloid differentiation
  1904. Rapamycinย inhibits proliferation of estrogen-receptor-positive breast cancer cells
  1905. An activatedย mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines andย inhibitionย of the pathway byย Rapamycinย and siRNA against โ€ฆ
  1906. Mammalian target ofย Rapamycinย contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids
  1907. Evaluation of antileukaemic effects ofย Rapamycinย in patients with imatinibโ€resistant chronic myeloid leukaemia
  1908. Antiproliferative effects ofย Rapamycinย as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines
  1909. Rapamycinย promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling
  1910. Mammalian target ofย Rapamycin: master regulator of cell growth in the nervous system
  1911. Binding ofย Rapamycinย analogs to calcium channels and FKBP52 contributes to their neuroprotective activities
  1912. Epstein Barr virus,ย Rapamycin, and host immune responses
  1913. Regression of subependymal giant cell astrocytoma withย Rapamycinย in tuberous sclerosis complex
  1914. Effect ofย Rapamycinย on wound healing: an experimental study
  1915. Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads toย Rapamycinย susceptibility
  1916. ASCT2 silencing regulates mammalian target-of-Rapamycinย growth and survival signaling in human hepatoma cells
  1917. Small molecule enhancers ofย Rapamycin-induced TORย inhibitionย promote autophagy, reduce toxicity in Huntingtonโ€™s disease models and enhance killing of โ€ฆ
  1918. Mammalian target ofย Rapamycinย (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin
  1919. Defects in skin ฮณฮด T cell function contribute to delayed wound repair inย Rapamycin-treated mice
  1920. Effective in vivo targeting of the mammalian target ofย Rapamycinย pathway in malignant peripheral nerve sheath tumors
  1921. Rapamycin, but not cyclosporine or FK506, alters natural killer cell function
  1922. IL-1ฮฒ-driven ST2L expression promotes maturation resistance inย Rapamycin-conditioned dendritic cells
  1923. Mitogen-activated protein kinase upregulates the dendritic translation machinery in long-term potentiation by controlling the mammalian target ofย Rapamycinย pathway
  1924. CXCR6 induces prostate cancer progression by the AKT/mammalian target ofย Rapamycinย signaling pathway
  1925. Combination strategy targeting the hypoxia inducible factor-1ฮฑ with mammalian target ofย Rapamycinย and histone deacetylase inhibitors
  1926. Pharmacometrics and delivery of novel nanoformulated PEG-b-poly (ฮต-caprolactone) micelles ofย Rapamycin
  1927. Calcineurin inhibitors andย Rapamycin: cancer protection or promotion?
  1928. A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target ofย Rapamycinย (mTOR) in high-protein dietโ€“induced weight loss
  1929. โ€ฆ exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target ofย Rapamycinย โ€ฆ
  1930. Endoplasmic reticulum and Golgi localization sequences for mammalian target ofย Rapamycin
  1931. Mammalian target ofย Rapamycinย (mTOR)ย inhibitionย activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute โ€ฆ
  1932. Rapamycinย inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro
  1933. Identification of a Highly Effectiveย Rapamycinย Schedule that Markedly Reduces the Size, Multiplicity, and Phenotypic Progression of Tobacco Carcinogenโ€“Induced โ€ฆ
  1934. Rapamycinย prevents the development of nephritis in lupus-prone NZB/WF1 mice
  1935. Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced byย Rapamycin
  1936. Rapamycinย as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells
  1937. Rapamycinย attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
  1938. Intramural Delivery ofย Rapamycinย With ฮฑvฮฒ3-Targeted Paramagnetic Nanoparticles Inhibits Stenosis After Balloon Injury
  1939. FK506 binding protein mediates glioma cell growth and sensitivity toย Rapamycinย treatment by regulating NF-ฮบB signaling pathway
  1940. Cytoplasmic and nuclear distribution of the protein complexesย mTORC1 andย mTORC2:ย Rapamycinย triggers dephosphorylation and delocalization of theย mTORC2 โ€ฆ
  1941. Oncogenic tyrosine kinase NPM/ALK induces activation of theย Rapamycin-sensitiveย mTORย signaling pathway
  1942. Target ofย Rapamycinย (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine
  1943. Antiangiogenic therapy with mammalian target ofย Rapamycinย inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer
  1944. Mammalian target ofย Rapamycinย and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy
  1945. Preparation and characterization ofย Rapamycin-loaded PLGA coating stent
  1946. Longitudinalย inhibitionย of PI3K/Akt/mTORย signaling by LY294002 andย Rapamycinย induces growth arrest of adult T-cell leukemia cells
  1947. Suppression of Peutz-Jeghers polyposis by targeting mammalian target ofย Rapamycinย signaling
  1948. Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor with potent in โ€ฆ
  1949. Rapamycinย retards growth and causes marked alterations in the growth plate of young rats
  1950. โ€ฆ fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target ofย Rapamycinย (mTOR) signaling cascade
  1951. Autophagy activation byย Rapamycinย eliminates mouse Malloryโ€Denk bodies and blocks their proteasome inhibitorโ€mediated formation
  1952. Mammalian target ofย Rapamycinย inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer
  1953. Defective TGF-ฮฒ signaling sensitizes human cancer cells toย Rapamycin
  1954. A retroinhibitionย approach reveals a tumor cellโ€“autonomous response toย Rapamycinย in head and neck cancer
  1955. Effects ofย Rapamycinย on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons
  1956. inhibitionย of mammalian target ofย Rapamycinย induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E โ€ฆ
  1957. Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt, and mammalian target ofย Rapamycinย in mammary carcinomas, mammary gland โ€ฆ
  1958. Targeting Protein Translation in Human Nonโ€“Small Cell Lung Cancer via Combined MEK and Mammalian Target ofย Rapamycinย Suppression
  1959. Activation of mammalian target ofย Rapamycinย complex 1 and insulin resistance induced by palmitate in hepatocytes
  1960. โ€ฆ concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target ofย Rapamycin/eIF4E โ€ฆ
  1961. Enhancing mammalian target ofย Rapamycinย (mTOR)โ€“targeted cancer therapy by preventingย mTOR/Raptorย inhibition-initiated,ย mTOR/Rictor-independent Akt activation
  1962. Leucine stimulates mammalian target ofย Rapamycinย signaling in C2C12 myoblasts in part throughย inhibitionย of adenosine monophosphate-activated protein kinase
  1963. Rapamycinย Inhibits Proliferation of Epstein-Barr Virusโ€“Positive B-cell Lymphomas Through Modulation of Cell-Cycle Protein Expression
  1964. Solution structure of the Legionella pneumophila Mip-Rapamycinย complex
  1965. Combined therapeutic effects of vinblastine andย Rapamycinย on human neuroblastoma growth, apoptosis, and angiogenesis
  1966. Azoospermia in a renal transplant recipient during sirolimus (Rapamycin) treatment
  1967. Differential involvement of IฮบB kinases ฮฑ and ฮฒ in cytokine-and insulin-induced mammalian target ofย Rapamycinย activation determined by Akt
  1968. The role of targeting mammalian target ofย Rapamycinย in lung cancer
  1969. Amelioration of protein misfolding disease byย Rapamycin: translation or autophagy?
  1970. Monitoring biological action ofย Rapamycinย in renal transplantation
  1971. Efficacy ofย Rapamycinย in scleroderma: a case study
  1972. Statin therapy, alone or withย Rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study
  1973. Target ofย Rapamycinย and LST8 proteins associate with membranes from the endoplasmic reticulum in the unicellular green alga Chlamydomonas reinhardtii
  1974. Regulation of mammalian target ofย Rapamycinย activity in PTEN-inactive prostate cancer cells by IฮบB kinase ฮฑ
  1975. โ€ฆ regulates hippocampal neurons by elevation of intracellular calcium and activation of calcium/calmodulin protein kinase II and mammalian target ofย Rapamycin
  1976. The Akt/mammalian target ofย Rapamycinย signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation
  1977. The mammalian target ofย Rapamycinย pathway as a potential target for cancer chemoprevention
  1978. Rapamycin: brain excitability studied in vitro
  1979. Rapamycinโ€mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae
  1980. Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion
  1981. Adiponectin signals in prostate cancer cells through Akt to activate the mammalian target ofย Rapamycinย pathway
  1982. Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target ofย Rapamycinย signalling to protein synthesis in L6 muscle cells
  1983. Phosphorylation of ribosomal p70 S6 kinase andย Rapamycinย sensitivity in human colorectal cancer
  1984. Mammalian Target ofย Rapamycinย Repression by 3, 3โ€ฒ-Diindolylmethane Inhibits Invasion and Angiogenesis in Platelet-Derived Growth Factor-Dโ€“Overexpressing โ€ฆ
  1985. Endothelial Akt signaling is rate-limiting forย Rapamycinย inhibitionย of mouse mammary tumor progression
  1986. Aging, stem cells, and mammalian target ofย Rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells
  1987. The mammalian target ofย Rapamycinย kinase and tumor growthย inhibition
  1988. Nonimmunosuppressive effects of mammalian target ofย Rapamycinย inhibitors
  1989. Rapamycinย reduces VEGF expression in retinal pigment epithelium (RPE) and inhibits RPE-induced sprouting angiogenesis in vitro
  1990. Interplay of PI3K and cAMP/PKA signaling, andย Rapamycin-hypersensitivity in TGFฮฒ1 enhancement of FSH-stimulated steroidogenesis in rat ovarian โ€ฆ
  1991. โ€ฆ human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinaseโ€“dependent mammalian target ofย Rapamycinย raptor complex 1 โ€ฆ
  1992. mTORย is theย Rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr (389) in p70S6k
  1993. Oncolytic virotherapy synergism with signaling inhibitors:ย Rapamycinย increases myxoma virus tropism for human tumor cells
  1994. Juvenile hormone connects larval nutrition with target ofย Rapamycinย signaling in the mosquito Aedes aegypti
  1995. Rapamycinย suppresses TLR4-triggered IL-6 and PGE2 production of colon cancer cells by inhibiting TLR4 expression and NF-ฮบB activation
  1996. Protein phosphatase 2A andย Rapamycinย regulate the nuclear localization and activity of the transcription factor GLI3
  1997. Effect ofย Rapamycinย therapy on coronary artery physiology early after cardiac transplantation
  1998. Low-doseย mTORย inhibitionย byย Rapamycinย attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat
  1999. Immunosuppression and tumor development in organ transplant recipients: the emerging dualistic role ofย Rapamycin
  2000. Bevacizumab andย Rapamycinย inhibit tumor growth in peritoneal model of human ovarian cancer
  2001. Effects of the dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging
  2002. IL-2โ€“ and IL-15โ€“induced activation of theย Rapamycin-sensitiveย mTORC1 pathway in malignant CD4+ T lymphocytes
  2003. Mammalian Target ofย Rapamycinย (mTOR) is Activated in Cutaneous Vascular Malformations in Vivo
  2004. Reduction of CCR5 with low-doseย Rapamycinย enhances the antiviral activity of vicriviroc against both sensitive and drug-resistant HIV-1
  2005. Evaluation of the mammalian target ofย Rapamycinย pathway and the effect ofย Rapamycinย on target expression and cellular proliferation in osteosarcoma cells from dogs
  2006. Differential effects ofย Rapamycinย in anti-GBM glomerulonephritis
  2007. Rapamycinย inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy
  2008. Coupling of mammalian target ofย Rapamycinย with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2a-and glycogen synthase โ€ฆ
  2009. Mammalian target ofย Rapamycinย and caspase inhibitors in polycystic kidney disease
  2010. Pharmacodynamic-guided modified continuous reassessment methodโ€“based, dose-finding study ofย Rapamycinย in adult patients with solid tumors
  2011. Statin-dependent suppression of the Akt/mammalian target ofย Rapamycinย signaling cascade and programmed cell death 4 up-regulation in renal cell carcinoma
  2012. Impact of mammalian target ofย Rapamycinย inhibitionย on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic โ€ฆ
  2013. Antiproliferative and proapoptotic effects ofย Rapamycinย and celecoxib in malignant melanoma cell lines
  2014. Role of the phosphoinositide 3-kinase-Akt-mammalian target of theย Rapamycinย signaling pathway in long-term potentiation and trace fear conditioning memory in rat โ€ฆ
  2015. Exploiting the mammalian target ofย Rapamycinย pathway in hematologic malignancies
  2016. Simultaneous hybrid coronary revascularization using totally endoscopic left internal mammary artery bypass grafting and placement ofย Rapamycinย eluting stents in the โ€ฆ
  2017. Degradation ofย Rapamycinย and its ring-opened isomer: role of base catalysis
  2018. Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21WAF1/CIP1 expression withย Rapamycin
  2019. Superoxide anions regulate TORC1 and its ability to bind Fpr1:ย Rapamycinย complex
  2020. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target ofย Rapamycinย complex 1
  2021. Topicalย Rapamycinย inhibits tuberous sclerosis tumor growth in a nude mouse model
  2022. Cardiac restricted overexpression of kinase-dead mammalian target ofย Rapamycinย (mTOR) mutant impairs theย mTOR-mediated signaling and cardiac function
  2023. Rapamycinย at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production
  2024. Mammalian target ofย Rapamycinย (mTOR) pathway signalling in lymphomas
  2025. Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 andย Rapamycinย combination therapy
  2026. Nucleophosmin mediates mammalian target ofย Rapamycinโ€“Dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes
  2027. Effects ofย Rapamycinย on cell proliferation and phosphorylation ofย mTORย and p70S6K in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB
  2028. Mammalian target ofย Rapamycinย inhibitionย halts the progression of proteinuria in a rat model of reduced renal mass
  2029. Fatty acid synthase inhibitors modulate energy balance via mammalian target ofย Rapamycinย complex 1 signaling in the central nervous system
  2030. Rapamycinย does not improve insulin sensitivity despite elevated mammalian target ofย Rapamycinย complex 1 activity in muscles of ob/ob mice
  2031. inhibitionย of apoptosis through localized delivery ofย Rapamycin-loaded nanoparticles prevented neointimal hyperplasia and reendothelialized injured artery
  2032. Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects ofย Rapamycin, mycophenolate, cyclosporin, azathioprine, and โ€ฆ
  2033. Regulatory effects of mammalian target ofย Rapamycin-mediated signals in the generation of arsenic trioxide responses
  2034. Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase-and mammalian target ofย Rapamycin-dependent mechanism
  2035. Nonโ€human primate fetal kidney transcriptome analysis indicates mammalian target ofย Rapamycinย (mTOR) is a central nutrientโ€responsive pathway
  2036. Compared effect of immunosuppressive drugs cyclosporine A andย Rapamycinย on cholesterol homeostasis key enzymes CYP27A1 and HMGโ€CoA reductase
  2037. On the action of cyclosporine A,ย Rapamycinย and tacrolimus on M. avium including subspecies paratuberculosis
  2038. Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target ofย Rapamycinย complex 1 (mTORC1)-mediated phosphorylation
  2039. Improved blood compatibility ofย Rapamycin-eluting stent by incorporating curcumin
  2040. Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target ofย Rapamycinย signaling through an extracellular signal-regulated kinase โ€ฆ
  2041. Monitoring antitumor efficacy ofย Rapamycinย in Kaposi sarcoma
  2042. Phosphatidylinositol 3-kinase-AKT-mammalian target ofย Rapamycinย pathway is essential for neuroendocrine differentiation of prostate cancer
  2043. Rapamycinย downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 โ€ฆ
  2044. Initial testing (stage 1) of theย mTORย inhibitorย Rapamycinย by the pediatric preclinical testing program
  2045. Insulinโ€like growth factorโ€1 (IGFโ€1) and leucine activate pig myogenic satellite cells through mammalian target ofย Rapamycinย (mTOR) pathway
  2046. Rapamycinย impairs ฮฒ-cell proliferation in vivo
  2047. โ€ฆ acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target ofย Rapamycinย โ€ฆ
  2048. Upstream signalingย inhibitionย enhancesย Rapamycinย effect on growth of kidney cancer cells
  2049. Hsf1 activation inhibitsย Rapamycinย resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis
  2050. Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand inย Rapamycin
  2051. The YCR079w gene confers aย Rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae
  2052. Combination ofย Rapamycinย and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiatesย mTORย blockade in breast cancer cells
  2053. โ€ฆ Signaling Pathway Induces Resistance to the Apoptotic Activities of SCH66336 (Lonafarnib) through Akt/Mammalian Target ofย Rapamycinโ€“Mediated Increases in โ€ฆ
  2054. Antiproliferative effect ofย Rapamycinย on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomeraseย inhibition
  2055. A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target ofย Rapamycinย inhibitor, in patients with relapsed or refractory hematologic โ€ฆ
  2056. Ocular toxicity and distribution of subconjunctival and intravitrealย Rapamycinย in horses
  2057. Response of U87 glioma xenografts treated with concurrentย Rapamycinย and fractionated radiotherapy: possible role for thrombosis
  2058. Mammalian target ofย Rapamycinย activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth
  2059. Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma postโ€“lung transplantation withย Rapamycinย treatment
  2060. Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target ofย Rapamycinย pathway in Drosophila
  2061. inhibitionย of mammalian target ofย Rapamycinย signaling by 2-(morpholin-1-yl) pyrimido [2, 1-ฮฑ] isoquinolin-4-one
  2062. Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide andย Rapamycin
  2063. Intracellular mechanisms of metabolism regulation: the role of signaling via the mammalian target ofย Rapamycinย pathway and other routes
  2064. Loss of tuberous sclerosis complex-2 function and activation of mammalian target ofย Rapamycinย signaling in endometrial carcinoma
  2065. The mammalian target ofย Rapamycinย pathway and its role in molecular nutrition regulation
  2066. Cotylenin A, a new differentiation inducer, andย Rapamycinย cooperatively inhibit growth of cancer cells through induction of cyclin G2
  2067. Effects ofย Rapamycinย in liver transplantation.
  2068. Rapamycinย inhibits multiple stages of c-Neu/ErbB2โ€“induced tumor progression in a transgenic mouse model of HER2-positive breast cancer
  2069. Rapamycinย enriches for CD4+ CD25+ CD27+ Foxp3+ regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with โ€ฆ
  2070. Rapamycinย down-regulates LDL-receptor expression independently of SREBP-2
  2071. Differential regulation of vascular endothelial growth factor by Akt and mammalian target ofย Rapamycinย inhibitors in cell lines derived from childhood solid tumors
  2072. Forkhead box protein O1 negatively regulates skeletal myocyte differentiation through degradation of mammalian target ofย Rapamycinย pathway components
  2073. Effects ofย Rapamycinย on active Heymann nephritis
  2074. Rationale for a phase I trial of erlotinib and the mammalian target ofย Rapamycinย inhibitor everolimus (RAD001) for patients with relapsed nonโ€“small cell lung cancer
  2075. Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target ofย Rapamycinย through the STAT3-SOCS3 pathway
  2076. Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย module for acute myelogenous leukemia therapy: from bench to bedside
  2077. Rapamycinย reduces CCR5 mRNA levels in macaques: potential applications in HIV-1 prevention and treatment
  2078. โ€ฆ and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target ofย Rapamycinย pathway in osteoblasts
  2079. Rapamycinย reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibitingย mTORย signaling pathway, enhancing G 1 cell cycle โ€ฆ
  2080. Rapamycinย enhances the number of alloantigen-induced human CD103+ CD8+ regulatory T cells in vitro
  2081. GADD34 inhibits mammalian target ofย Rapamycinย signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress
  2082. Delivery ofย Rapamycinโ€loaded nanoparticle down regulates ICAMโ€1 expression and maintains an immunosuppressive profile in human CD34+ progenitorโ€derived โ€ฆ
  2083. Four-year clinical follow-up of theย Rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital registry
  2084. Human melanoma cytolysis by combinedย inhibitionย of mammalian target ofย Rapamycinย and vascular endothelial growth factor/vascular endothelial growth factor โ€ฆ
  2085. Surgical woundโ€healing complications in heart transplant recipients treated withย Rapamycin
  2086. Mammalian target ofย Rapamycinย as a target in hematological malignancies
  2087. Does addition of estradiol improve the efficacy of aย Rapamycin-eluting stent? Results of the ISAR-PEACE randomized trial
  2088. The effects ofย Rapamycinย in the progression of renal fibrosis
  2089. Mechanism of apoptosis induced by IFN-ฮฑ in human myeloma cells: role of Jak1 and Bim and potentiation byย Rapamycin
  2090. p21-activated kinase 1 is activated through the mammalian target ofย Rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in โ€ฆ
  2091. Effect of supplemental dietary zinc on the mammalian target ofย Rapamycinย (mTOR) signaling pathway in skeletal muscle and liver from post-absorptive mice
  2092. Combined treatment with triptolide andย Rapamycinย prolongs graft survival in a mouse model of cardiac transplantation
  2093. Synergistic effect ofย mTORย inhibitorย Rapamycinย and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells
  2094. Rapamycinย stimulates arginine influx through CAT2 transporters in human endothelial cells
  2095. Mammalian target ofย Rapamycinย is the key effector of phosphatidylinositol-3-OHโ€“initiated proliferative signals in the thyroid follicular epithelium
  2096. Down-regulation of phosphatidylinositol 3โ€ฒ-kinase/AKT/molecular target ofย Rapamycinย metabolic pathway by primary letrozole-based therapy in human breast cancer
  2097. The combination of novel low molecular weight inhibitors of RAF (LBT613) and target ofย Rapamycinย (RAD001) decreases glioma proliferation and invasion
  2098. EMAP-II downregulation contributes to the beneficial effects ofย Rapamycinย after vascular injury
  2099. Rescue of Degradationโ€Prone Mutants of the FK506โ€Rapamycinย Binding (FRB) Protein with Chemical Ligands
  2100. Antiproliferative and overadditive effects ofย Rapamycinย and FTY720 in pancreatic cancer cells in vitro
  2101. Rapamycinย for treatment of refractory dysthyroid compressive optic neuropathy
  2102. Randomized trial ofย Rapamycin-and paclitaxel-eluting stents with identical biodegradable polymeric coating and design
  2103. Nutrient content of diet affects the signaling activity of the insulin/target ofย Rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae
  2104. Rapamycinย delays growth of Wnt-1 tumors in spite of suppression of host immunity
  2105. Rapamycinย together with herceptin significantly increased antiโ€tumor efficacy compared to either alone in ErbB2 over expressing breast cancer cells
  2106. Short-and long-term effects of cytochalasin D, paclitaxel andย Rapamycinย on wall thickening in experimental porcine vein grafts
  2107. Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target ofย Rapamycinย pathway in Barrettโ€™s-associated esophageal adenocarcinoma
  2108. A phase II study of oral mammalian target ofย Rapamycinย (mTOR) inhibitor, RAD001 (everolimus), in patients with recurrent endometrial carcinoma (EC)
  2109. Rapamycinย shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination
  2110. External application ofย Rapamycin-eluting film at anastomotic sites inhibits neointimal hyperplasia in a canine model
  2111. Rapamycinย blunts nutrient stimulation of eIF4G, but not PKCฮต phosphorylation, in skeletal muscle
  2112. ABT-263 andย Rapamycinย act cooperatively to kill lymphoma cells in vitro and in vivo
  2113. mTORย inhibitors (Rapamycinย and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours
  2114. DCO2 on-line measurement used inย Rapamycinย fed-batch fermentation process
  2115. Identification of theย Rapamycinโ€sensitive phosphorylation sites within the Ser/Thrโ€rich domain of the yeast Npr1 protein kinase
  2116. Golgi Manganese Transport Is Required forย Rapamycinย Signaling in Saccharomyces cerevisiae
  2117. How to control lymphangiogenesis: A novel role forย Rapamycin
  2118. Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target ofย Rapamycin
  2119. Components of the Vid30c are needed for theย Rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae
  2120. An approach to analyse the specific impact ofย Rapamycinย on mRNA-ribosome association
  2121. Ex vivoย Rapamycinย generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection
  2122. Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer
  2123. Rapamycinย prevents mesenteric neoโ€angiogenesis and reduces splanchnic blood flow in portal hypertensive mice
  2124. Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation,ย Rapamycinย and paclitaxel
  2125. Chylous ascites in a renal transplant recipient under sirolimus (Rapamycin) treatment
  2126. Combination antifungal therapy involving amphotericin B,ย Rapamycinย and 5-fluorocytosine using PEG-phospholipid micelles
  2127. Serotonin Induces Memory-Like,ย Rapamycin-Sensitive Hyperexcitability in Sensory Axons of Aplysia That Contributes to Injury Responses
  2128. Activation of the mammalian target ofย Rapamycinย complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bษ› mRNA translation and protein โ€ฆ
  2129. Human herpesvirusโ€8 (HHVโ€8)โ€associated primary effusion lymphoma in two renal transplant recipients receivingย Rapamycin
  2130. An RNA Interference Screen Identifies a Novel Regulator of Target ofย Rapamycinย That Mediates Hypoxia Suppression of Translation in Drosophila S2 Cells
  2131. Identification of AUF1 as aย Rapamycin-responsive binding protein to the 5โ€ฒ-terminal oligopyrimidine element of mRNAs
  2132. Mitogen-stimulated andย Rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells
  2133. Targeting 14-3-3 sensitizes native and mutant BCR-ABL toย inhibitionย with U0126,ย Rapamycinย and Bcl-2 inhibitor GX15-070
  2134. Modulation of the activities of AMPโ€activated protein kinase, protein kinase B, and mammalian target ofย Rapamycinย by limiting energy availability with 2โ€deoxyglucose
  2135. PTEN andย Rapamycinย inhibiting the growth of K562 cells through regulatingย mTORย signaling pathway
  2136. Role of adenosine 5โ€ฒ-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target ofย Rapamycinย signaling
  2137. Pharmacokinetics of sirolimus (Rapamycin) in subjects with severe hepatic impairment
  2138. โ€ฆ Preconditioning Decreases Myocardial Infarction in Rabbits via Up-regulation of Hypoxia Inducible Factor 1 That Is Mediated by Mammalian Target ofย Rapamycin
  2139. Stress and IGF-I differentially control cell fate through mammalian target ofย Rapamycinย (mTOR) and retinoblastoma protein (pRB)
  2140. โ€ฆ of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3โ€kinaseโ€“Aktโ€“mammalian target ofย Rapamycinย โ€ฆ
  2141. Possible involvement of persistent activity of the mammalian target ofย Rapamycinย pathway in the cisplatin resistance of AFP-producing gastric cancer cells
  2142. Cyclin B synthesis andย Rapamycinโ€sensitive regulation of protein synthesis during starfish oocyte meiotic divisions
  2143. Comparison of a polymerโ€freeย Rapamycinโ€eluting stent (YUKON) with a polymerโ€based paclitaxelโ€eluting stent (TAXUS) in realโ€world coronary artery lesions
  2144. The Rheb switch 2 segment is critical for signaling to target ofย Rapamycinย complex 1
  2145. Cyclosporine A andย Rapamycinย induce in vitro cholesteryl ester transfer protein activity, and suppress lipoprotein lipase activity in human plasma
  2146. Rapamycinย reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency โ€ฆ
  2147. Threeโ€year clinical outcomes after coronary stenting of chronic total occlusion using sirolimusโ€eluting stents: Insights from theย Rapamycinโ€eluting stent evaluated at โ€ฆ
  2148. Chronic alcohol consumption alters mammalian target ofย Rapamycinย (mTOR), reduces ribosomal p70s6 kinase and p4E-BP1 levels in mouse cerebral cortex
  2149. Intrinsically lower AKT, mammalian target ofย Rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia โ€ฆ
  2150. โ€ฆ preclinical studies: timing of treatment, combination of aย Rapamycinย analog (CCI-779) and interferon-gamma, and comparison ofย Rapamycinย to CCI-779
  2151. Rapamycinย limits formation of active eukaryotic initiation factor 4F complex following meal feeding in rat hearts
  2152. CD8+ Tโ€Cell Depletion andย Rapamycinย Synergize with Combined Coreceptor/Stimulation Blockade to Induce Robust Limb Allograft Tolerance in Mice
  2153. Antineoplastic effect ofย Rapamycinย is potentiated byย inhibitionย of IRS-1 signaling in prostate cancer cells xenografts
  2154. Mammalian target ofย Rapamycinย pathwayย inhibitionย enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines
  2155. The Cairo kidney center protocol forย Rapamycin-based sequential immunosuppression in kidney transplant recipients: 2-year outcomes
  2156. โ€ฆ of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target ofย Rapamycinย โ€ฆ
  2157. Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins andย Rapamycin
  2158. IGF-I receptorย inhibitionย combined withย Rapamycinย or temsirolimus inhibits neuroblastoma cell growth
  2159. Chronic allograft dysfunction: can we use mammalian target ofย Rapamycinย inhibitors to replace calcineurin inhibitors to preserve graft function?
  2160. The mammalian target ofย Rapamycinย complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5โ€ฒ-untranslated region in the โ€ฆ
  2161. Rapamycinย enhances the anti-tumor effect of gemcitabine in pancreatic cancer cells.
  2162. Renal cortex neuronal nitric oxide synthase in response toย Rapamycinย in kidney transplantation
  2163. The MAP kinase-activated protein kinase Rck2p plays a role inย Rapamycinย sensitivity in Saccharomyces cerevisiae and Candida albicans
  2164. โ€ฆ Factorโ€1 and Transforming Growth Factorโ€ฮฒ Controls the Quiescence/Cycling Switch of CD34+ Progenitors Through FoxO3 and Mammalian Target ofย Rapamycin
  2165. The effect ofย Rapamycinย on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats
  2166. Rapamycinย reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation
  2167. Reversal of tacrolimusโ€related hypertrophic cardiomyopathy after conversion toย Rapamycinย in a pediatric liver transplant recipient
  2168. Mechanisms of mammalian target ofย Rapamycinย inhibitionย in sarcoma: present and future
  2169. siRNA targeting mammalian target ofย Rapamycinย (mTOR) attenuates experimental proliferative vitreoretinopathy
  2170. Synthesis, characterization and antiproliferative activity ofย Rapamycin-loaded poly (N-isopropylacrylamide)-based nanogels in vascular smooth muscle cells
  2171. Prolongation of cardiac allograft survival byย Rapamycinย and the invariant natural killer T cell glycolipid agonist OCH
  2172. Rapamycinย Inhibits Growth Factor-Induced Cell Cycle Regulation in Pancreatic ฮฒ Cells
  2173. Molecular impacts ofย Rapamycin-based drug combinations: combiningย Rapamycinย with gemcitabine or imatinib mesylate (Gleevec) in a human leiomyosarcoma model
  2174. Rapamycin-induced cytotoxic signal transduction pathway
  2175. Effect of rifampicin to inhibitย Rapamycin-induced autophagy via the suppression of protein phosphatase 2A activity
  2176. Specificย mTORย inhibitorย Rapamycinย enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea โ€ฆ
  2177. Requirements of phosphatidylinositol-3 kinase and mammalian target ofย Rapamycinย for estrogen-induced proliferation in uterine leiomyoma-and myometrium-derived โ€ฆ
  2178. Mass balance inย Rapamycinย autoxidation
  2179. Targeting the mammalian target ofย Rapamycinย in myxoid chondrosarcoma
  2180. Acetaldehyde promotesย Rapamycin-dependent activation of p70S6K and glucose uptake despiteย inhibitionย of Akt andย mTORย in dopaminergic SH-SY5Y human โ€ฆ
  2181. Conversion toย Rapamycinย immunosuppression for malignancy after kidney transplantation
  2182. Normal phase and reverse phase HPLC-UV-MS analysis of process impurities forย Rapamycinย analog ABT-578: Application to active pharmaceutical ingredient process โ€ฆ
  2183. Non-Conventional method for evaluation and optimization of medium components forย Rapamycinย production by Streptomyces hygroscopicus
  2184. Administration of triiodo-L-thyronine into dorsal hippocampus alters phosphorylation of Akt, mammalian target ofย Rapamycin, p70S6 kinase and 4E-BP1 in rats
  2185. Possible mechanism by whichย Rapamycinย increases cyclosporine nephrotoxicity
  2186. โ€ฆ Extracellular Signal-regulated Kinase 1/2 and c-Jun NH2-Terminal Kinase Downstream of Phosphatidylinositol 3-Kinase and Mammalian Target ofย Rapamycin
  2187. Adverse effects of mammalian target ofย Rapamycinย inhibitors during the postoperative period after cardiac transplantation
  2188. ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination withย Rapamycinย is effective for subcutaneous hepatocellular carcinoma xenograft
  2189. Neointimal expression ofย Rapamycinย receptor FK506-binding protein FKBP12: postinjury animal and human in-stent restenosis tissue characteristics
  2190. Successful treatment of post-renal transplant gastric and pulmonary Kaposiโ€™s sarcoma with conversion toย Rapamycinย treatment
  2191. A comparison of clinical and angiographic outcomes after Excel bioabsorbable polymer versus Firebird durable polymerย Rapamycin-eluting stent for the treatment of โ€ฆ
  2192. Effect ofย Rapamycinย on hepatocyte function and proliferation induced by growth factors
  2193. Lentiviral vectors mediate nonimmunosuppressiveย Rapamycinย analog-induced production of secreted therapeutic factors in the brain: regulation at the level of โ€ฆ
  2194. Rapamycinย bypasses vesicle-mediated signaling events to activate Gln3 in Saccharomyces cerevisiae
  2195. Nanoparticle albumin-bound (nab)ย Rapamycinย as an anticancer agent
  2196. Rapamycinย conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: implications for the mechanisms of Hsp mRNA translation
  2197. Differential modulation of mitogen driven proliferation and homeostasis driven proliferation of T cells byย Rapamycin, Ly294002 and chlorophyllin
  2198. A phase 1b study of oralย Rapamycinย (sirolimus) in patients with advanced malignancies
  2199. Rapamycin-loaded poly (lactic-co-glycolic) acid nanoparticles for intraarterial local drug delivery: preparation, characterization, and in vitro/in vivo release
  2200. A Combination of Donor Specific Transfusion andย Rapamycinย Prolonges Cardiac Allograft Survival in Mice
  2201. Immunoassay determination ofย Rapamycin: reliability of the method with respect to liquid chromatography mass spectrometric quantification
  2202. Thrombin induces osteoprotegerin synthesis via phosphatidylinositol 3โ€ฒโ€kinase/mammalian target ofย Rapamycinย pathway in human periodontal ligament cells
  2203. Galectin-1 upregulates glucose transporter-1 expression level via protein kinase C, phosphoinositol-3 kinase, and mammalian target ofย Rapamycinย pathways in mouse โ€ฆ
  2204. inhibitionย of the mammalian target ofย Rapamycinย (mTOR) in a case of refractory primary cutaneous anaplastic large cell lymphoma
  2205. Magic withย Rapamycin
  2206. Rapamycinย promotes emergence of IL-10-secreting donor lymphocyte infusion-derived T cells without compromising their graft-versus-leukemia reactivity
  2207. Rapamycinย and cyclosporine have different effects on expression of Ang-1 and Ang-2 and Tie2 in rat renal allograft with chronic allograft nephropathy
  2208. Phorbol 12-myristate 13-acetate and serum synergize to promoteย Rapamycin-insensitive cell proliferation via protein kinase C-eta
  2209. A recent application of fluoro-18-deoxyglucose positron emission tomography, treatment monitoring with a mammalian target ofย Rapamycinย inhibitor: an example โ€ฆ
  2210. Orally administeredย Rapamycin, dacarbazine or both for treatment of human melanoma evaluated in severe combined immunodeficiency mice
  2211. โ€ฆ /p70S6K signaling pathway constitutively activated in esophageal squamous cell carcinona cell lines andย inhibitionย of the pathway byย Rapamycinย and siRNA against โ€ฆ
  2212. Anti-CD25 mAb, anti-IL2 mAb, and IL2 block tolerance induction through anti-CD154 mAb andย Rapamycinย in xenogeneic islet transplantation
  2213. Effect of chemotherapy with cisplatin andย Rapamycinย against Hep-2 cells in vitro
  2214. A new trick for an old drug:ย mTORย inhibitorย Rapamycinย augments the effect of fluorouracil on hepatocellular carcinoma by inducing cell senescence
  2215. Loss of phosphatase and tensin homologue deleted on chromosome 10 and phosphorylation of mammalian target ofย Rapamycinย are associated with progesterone โ€ฆ
  2216. โ€ฆ MCF-7 breast cancer tumors are associated with hyperactivation of theย mTORย pathway: therapeutic implications for combination therapy withย Rapamycin
  2217. Rapamycin, Mycophenolate Mofetil, Methylprednisolone, and Cytotoxic T-Lymphocyteโ€“Associated Antigen 4 Immunoglobulinโ€“Based Conditioning Regimen to Induce โ€ฆ
  2218. Long-term effects ofย Rapamycinย treatment on insulin mediated phosphorylation of Akt/PKB and glycogen synthase activity
  2219. A fast and simple method to prepare the FKBP-Rapamycinย binding domain of human target ofย Rapamycinย for NMR binding assays
  2220. Dentritic cell derived IL-18 production is inhibited byย Rapamycinย and sanglifehrin A, but not cyclosporine A
  2221. Hypoxia-induced hypomyelination in the developing brain is mammalian target ofย Rapamycin-4E-binding protein-1 signaling dependent
  2222. Combination of Nab-Rapamycinย and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)
  2223. Effects ofย mTORย inhibitorย Rapamycinย on Smad 3 protein and collagen type I expression in rat myocardial fibroblasts infected with coxsackie virus B 3
  2224. Synergistic effect ofย Rapamycinย (RPM) and PD98059 on cell cycle andย mTORย signal transduction in human colorectal cancer cells
  2225. A phase II study of mammalian target ofย Rapamycinย (mTOR) inhibitor RAD001 plus imatinib mesylate (IM) in patients with previously treated advanced renal carcinoma โ€ฆ
  2226. Influence ofย Rapamycinย on rat macrophage viability and chemotaxis toward allogenic pancreatic islet supernates
  2227. Orally administeredย Rapamycinย does not modify rat aortic vascular tone
  2228. Rapamycinย inhibits the growth of cholangiocarcinoma cells in vitro
  2229. Sirolimus (Rapamycin) induced proteinuria in a patient undergoing allogeneic hematopoietic stem cell transplant
  2230. Induction effect ofย Rapamycinย combined paclitaxel on apoptosis of ovarian cancer cell lines A2780 and SKOV3 and the molecular mechanism
  2231. Temozolomide combined with the PI3K inhibitor LY294002 or theย mTORย inhibitorย Rapamycinย inhibits melanoma cell growth, survival and invasion
  2232. Negative inotropic effect ofย Rapamycinย on isolated human cardiomyocytes
  2233. PDE4B Activity Controls Glucorticoid andย Rapamycinย Effects in DLBCL.
  2234. Effects ofย Rapamycinย on intracellular cholesterol homeostasis of glomerular mesangial cell in the presence of interleukin-1ฮฒ
  2235. TOR (target ofย Rapamycin) as an anti-cancer target
  2236. The expression of mammalian target ofย Rapamycinย in Ishikawa and HEC-1A cells
  2237. Cancer and transplantation intersect at the mammalian target ofย Rapamycin
  2238. Expression of connective tissue growth factor in renal interstitial fibrosis after ureteral obstruction and effects ofย Rapamycinย thereupon: experiment with rats
  2239. Rapamycinย induces Balb/c murine CD4^+ CD25^+ foxp3^+ T cells proliferations
  2240. Mannan and peptidoglycan induce COXโ€2 protein in human PMN via the mammalian target ofย Rapamycin
  2241. Establishment of a Conjugation System for theย Rapamycinย Producer Streptomyces hygroscopicus NRRL5491 [J]
  2242. Effeet ofย Rapamycinย onย mTORย and eIF-4E expression in coxsackievirus B3-induced rat myocardial cells [J]
  2243. Effects ofย Rapamycinย on human hepatocellular carcinoma xenografts in nude mice [J]
  2244. Induction of PPAR gamma signaling and autophagy as a mechanism mediating acquiredย Rapamycinย resistance in breast cancer models
  2245. A drug interaction study of sorafenib (S) andย Rapamycinย (R) in patients with advanced malignancies
  2246. Regression of Pulmonary Lymphangioleiomyomatosis (PLAM)-Associated Retroperitoneal Angiomyolipoma Postโ€“Lung Transplantation Withย Rapamycinย Treatment
  2247. Initial use ofย Rapamycinย after kidney transplantation
  2248. Combination of CP-751871, a human monoclonal antibody against the IGF-1 receptor, withย Rapamycinย results in a highly effective therapy for xenografts derived from โ€ฆ
  2249. Rapamycinย controls multiple signalling pathways involved in cancer cell survival
  2250. Phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย pathway is critical for survival and proliferation of pancreatic cancer stem-like side population cells
  2251. Long-term limb allograft survival using a short course of anti-CD45RB monoclonal antibody, LF 15-0195, andย Rapamycinย in a mouse model
  2252. Resveratrol-andย Rapamycin-induced Morphological Changes to Human Epithelial Colon Cancer DLD-1 Cells
  2253. Phosphoinositide 3-kinase (PI3K) and nutrient sensingย mTORย (mammalian target ofย Rapamycin) pathways control T lymphocyte trafficking
  2254. Does the use of paclitaxel orย Rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
  2255. Preclinical rationale for combination targeted therapy in advanced clear cell renal cell carcinoma (RCC): Abrogation ofย Rapamycin-mediated induction of AKT โ€ฆ
  2256. Effect ofย Rapamycinย on CD4 (+) CD25 (+) regulatory T cells in allo-transplantation tolerance model
  2257. Effects of constant magnetic fields on proliferation and migration of endothelial progenitor cells underย Rapamycinย intervention: experiment with rats
  2258. Effect ofย Rapamycinย on expression of origin recognition complex 1 mRNA in vascular smooth muscle cells [J]
  2259. The different effects of cyclosporin A andย Rapamycinย on regulatory CD4+CD25+ T cells: potential relationship with transplant tolerance induction
  2260. Experimental study of stent-based delivery ofย Rapamycinย and tirofiban on preventing in-stent thrombosis and restenosis [J]
  2261. The clinical contrast investigation ofย Rapamycinย eluting stent between domestic-made and imported [J]
  2262. Perivascular delivery ofย Rapamycinย in pluronic gel inhibits neointimal hyperplasia in a rat carotid artery injury model, and the complementary role of carotid โ€ฆ
  2263. Effect ofย Rapamycinย on the cell cycle arrest of T lymphocytes
  2264. mTORย kinase inhibitors exhibit properties that distinguish them fromย Rapamycin
  2265. โ€ฆ insulin-like growth factor-1 receptor (IGF-1R), enhances the anti-tumor activities of Tarceva in non-small cell lung carcinoma (NSCLC) andย Rapamycinย in sarcoma cell โ€ฆ
  2266. Conversion toย Rapamycinย in a renal transplant patient with von Hippel-Lindau disease: encouraging resultsโ€”a case report
  2267. Rapamycinย to the rescue!
  2268. Changes in FDG-PET in response toย Rapamycinย (R) correlated with Akt pathwayย inhibitionย and not with clinical outcome
  2269. Rapamycinย inhibits proliferation of cells from TSC skin tumors.
  2270. Expression of mammalian target ofย Rapamycinย and p70 S6 kinase in rabbit periodontal tissues remodeling during orthodontic tooth movement
  2271. Glucose transporter 12 and mammalian target ofย Rapamycinย complex 1 signaling: a new target for diabetes-induced renal injury?
  2272. Clinical Application of Mammalian Target ofย Rapamycinย Inhibitor in Kidney Transplantation
  2273. SYNERGISTIC EFFECT OF CYCLOSPORINE INย Rapamycin-INDUCE DIABETIC DISEASE: 1937
  2274. In Vitro Release ofย Rapamycinย Sustained Eluting Stent Detected by a New Designed Circulating Device
  2275. Cause analysis and treatment ofย Rapamycin-eluting stent thrombosis [J]
  2276. Elevated phosphorylated mammalian target ofย Rapamycinย (p-mTOR) expression in human neoplasms
  2277. Comparison between the Inhibitory and Cytotoxic Effects ofย Rapamycinย and Paclitaxel on Endothelial Cell Proliferation
  2278. Treatment with sodium butyrate andย Rapamycinย inhibit growth of human cervical cancer cells
  2279. Pediatric Preclinical Testing Program (PPTP) evaluation of theย mTORย inhibitorย Rapamycin
  2280. The application ofย Rapamycinย drug-eluting stents in elderly patients with acute myocardial infarction [J]
  2281. Effect of mammalian target ofย Rapamycinย inhibitors on neuroblastoma MYCN expression and tumor growth
  2282. Efficacy and Safety Study ofย Rapamycinย in Treating Mesangial Proliferative Glomerulonephritis: Analysis of 11 Cases
  2283. Effect of Orthodontics on Mammalian Target ofย Rapamycinย and p70 S6 Kinase in Rabbit Periodontal Tissues [J]
  2284. Rapamycinย affects eIF-4E expression in rat myocardial fibroblasts infected by Coxsackievirus B3
  2285. Local appliedย Rapamycinย inhibits intimal hyperplasia in vein graft after CABG
  2286. Human monoclonal antibody CP751871, combined withย Rapamycinย is effective treatment for childhood sarcoma xenografts
  2287. P1-084: Mammalian target ofย Rapamycinย (mTOR)ย inhibitionย by RAD001 in patients (pts) with reccurent non-small cell lung cancer (NSCLC): Use of 18F โ€ฆ
  2288. The application ofย Rapamycinย drug-eluting stents in elderly patients with coronary heart disease [J]
  2289. Progress ofย Rapamycinย in hepatocellular carcinoma
  2290. Predictingย Rapamycinย response using pathway profile in a population of genetically engineered hHer2 driven breast tumor model
  2291. Effect of conversion from calcineurin inhibitors toย Rapamycinย on chronic allograft nephropathy
  2292. Theย mTORย inhibitorย Rapamycinย demonstrates activity against AML in combination with imatinib mesylate and with 5-azacytidine.
  2293. Effeet ofย Rapamycinย onย mTORย and eIF-4E expression in coxsackievirus B3-induced rat myocardial cells
  2294. Combined regimen ofย Rapamycinย and ciclosporin in long-term follow-up in renal allograft recipients
  2295. Rapamycinย modulates the maturation of rat bone marrow-derived dendritic cells
  2296. Experimental study onย Rapamycin-batroxobin eluting stent and its prevention of coronary restenosis after angiophaty [J]
  2297. Cellular differentiation ofย Rapamycin, PI3 kinase and TOR kinase inhibitors
  2298. Histone deacetylaseย inhibitionย with LBH589 inhibits theย Rapamycinย insensitive Rictor-mTORย (mTORC2) complex and translation initiation factor eIF4E activation in โ€ฆ
  2299. 9B-6ย inhibitionย of Smooth Muscle Proliferation by Ultrasound-Triggered Release ofย Rapamycinย from Microbubbles
  2300. Combination of the VEGF receptor tyrosine kinase sunitinib and theย mTORย inhibitorย Rapamycinย leads to tumor regression in the RENCA model
  2301. Toxicology and safety pharmacology of nanoparticle albumin-bound (nab)ย Rapamycinย (ABI-009)
  2302. Rapamycinย potentiates the effects of paclitaxel in endometrial cancer cells throughย inhibitionย of cell proliferation and induction of apoptosis.
  2303. Expression and secretion of VEGF in solid tumor cells is mediated by the mammalian target ofย Rapamycinย (mTOR)
  2304. The design and pharmacokinetics in vivo ofย Rapamycin-PLGA membrane eluting stent [J]
  2305. Rapamycinย combined with donor bone marrow-derived immature dendritic cells induces mouse skin allograft tolerance
  2306. Anti-Proliferative Effect ofย Rapamycinย on Human T Cell Leukemia Cell Line Jurkat by Cell Cycle Arrest and Telomeraseย inhibition.
  2307. Phase I study of gefitinib andย Rapamycinย in adult patients with recurrent glioblastoma multiforme (GBM)
  2308. Rapamycin-inducedย inhibitionย of HTLV-I LTR activity is rescued by c-Myb
  2309. Effect of RNA interference targeting mammalian target ofย Rapamycinย on the proliferation of vascular smooth muscle cell and the intimal hyperplasia
  2310. Anti-Cancer Effects ofย Rapamycinย on U937 Cell Line.
  2311. Comparison of inflammatory markers and angiographic outcomes after implantation ofย Rapamycinย and paclitaxel-eluting stents
  2312. The roles of mammalian target ofย Rapamycinย (mTOR) and p21 in the autophagy pathway after DNA mismatch repair processing of 6-thioguanine
  2313. Molecular determinants of sensitivity toย Rapamycinย in NSCLC
  2314. Dasatinib andย Rapamycinย synergistically inhibit the proliferation of cells expressing oncogenic KIT kinase via globalย inhibitionย of AKT-dependent signaling
  2315. Anti-angiogenic activity ofย Rapamycinย inย Rapamycin-sensitive and-resistant tumor xenograft models
  2316. Mammalian target ofย Rapamycinย impairs insulinโ€™s ability to promote protein kinase B phosphorylation in isolated rat skeletal muscle
  2317. Dual Effects ofย Rapamycinย on Immuno-suppression and Tumorย inhibition
  2318. Rapamycinย Inhibits Proliferation of Human Lung Cancer Cell Lines [J]
  2319. Combination therapy withย Rapamycinย and atorvastatin
  2320. PI-103, a Dual Inhibitor of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target ofย Rapamycin, Has Cytotoxic Activity in T-Cell Acute Lymphoblastic โ€ฆ
  2321. The effects ofย Rapamycinย on body weight and insulin resistance in KKAy mice
  2322. Cell Proliferation in Multiple Rat Tissues In Vivo isย Rapamycinย Resistant
  2323. The Effect ofย Rapamycinย on Repair of Liver Ischemia/Reperfusion Injury
  2324. Genetically engineered murine tumor models for drug response prediction: population based pathway profiles predict response toย Rapamycinย in a HER2 driven breast โ€ฆ
  2325. The effect ofย Rapamycinย on PSA kinetics in men without prostate cancer
  2326. Chronic exposure toย Rapamycinย induces endothelial dysfunction in vitro
  2327. Antiproliferative effects ofย mTORย inhibitionย withย Rapamycinย (RAP) either given as a single agent or in combination with carboplatin and paclitaxel in Human Head and โ€ฆ
  2328. P158-M Expression of c-kit, p-mTORย and p-NFKappaB in angiolymphoid hyperplasia with eosinophilia: Potential for therapy with imitanib mesylate,ย Rapamycinย and โ€ฆ
  2329. Use ofย Rapamycinย to inhibit VEGF for the treatment of primary effusion lymphoma
  2330. Rapamycinย and CCI-779 suppress the growth of hepatocellular carcinoma cells
  2331. Combined effects ofย Rapamycinย and bicalutamide in androgen-dependent and-independent prostate cancer cells
  2332. Cholangiocarcinoma cells are selectively susceptible toย Rapamycinย treatment
  2333. The Mammalian Target ofย Rapamycinย and Multiple Myeloma
  2334. Rapamycinย modulates the eNOS versus shear stress relationship
  2335. Effect ofย Rapamycinย on the Proliferation and Apoptosis of Human Leukemia Cell Line HL-60 [J]
  2336. EFFECTS OFย Rapamycinย COMBINED IMMUNOSUPPRESSION ON RENAL FUNCTION AFTER LIVER TRANSPLANTATION
  2337. Effects ofย Rapamycinย on proliferation, function and cell-cycle of mouse T lymphocytes in vitro
  2338. Mammalian target ofย Rapamycinย and leukemia treatment
  2339. Clinical utility of combined administration ofย Rapamycinย and low dose of cyciosporin a in kidney transplantation recipients
  2340. Rapamycinย Induced Transactivation of EGFR: Implications in the Regulation of Cellular Apoptosis
  2341. The mammalian target ofย Rapamycinย (mTOR). Foreword.
  2342. Mammalian Target ofย Rapamycinย Activation Impairs
  2343. Clinical application ofย Rapamycin-eluting stent in coronary artery disease
  2344. Differential response ofย mTORC1 andย mTORC2 toย Rapamycinย inย Rapamycin-sensitive and-resistant tumor xenograft models
  2345. Effect of IGFโ€I andย Rapamycinย on diaphragm muscle atrogenes with malnutrition
  2346. Functional genomic identification and validation ofย Rapamycinย response genes using high throughput RNA interference
  2347. Rapamycinย increases sensitivity to cisplatin in mesothelioma cell lines
  2348. Rapamycinย inhibitionย of cell motility is associated with its suppression of synthesis of GTPases
  2349. Yeast as a Model to Study the Immunosuppressive and Chemotherapeutic Drugย Rapamycin
  2350. MANAGEMENT AND LONG-TERM OUTCOMES OF WOUND-HEALING COMPLICATIONS ASSOCIATED WITHย Rapamycin: 1108
  2351. Rapamycinย Augments Akt Activation in In Vitro and In Vivo Models of Cardiac Hypertrophy
  2352. The study of anti-proliferation effect ofย Rapamycinย on human breast cancer MCF-7 cells under hypoxia [J]
  2353. Rapamycinย Reduces CCR5 Density Levels
  2354. Rapamycinย inhibits Stearoyl-CoA Desaturase 1 expression in breast cancer cell lines.
  2355. Overexpression analysis reveals novel growth regulators in the target ofย Rapamycinย signaling pathway
  2356. Nutrient Stimulation of eIF4G Phosphorylation, but not PKC isย Rapamycinย Sensitive in Skeletal Muscle
  2357. Role ofย Rapamycinย on cultured human Tenonโ€ฒ s capsule fibroblasts
  2358. Statins andย Rapamycinย act synergistically to enhance vascular endothelial cytoprotection
  2359. Antitumor activity ofย Rapamycinย and octreotide as single agents or in combination in neuroendocrine tumors
  2360. Acuteย Rapamycinย Treatment Does Not Improve In Vivo Insulin Action in Ob/Ob or High Fat Fed Mice
  2361. Administration ofย Rapamycinย in vivo and in vitro prolonged allograft survival associated with iTregs
  2362. THE EFFECT OF LIVER REGENERATION ONย Rapamycinย PHARMACOKINETICS: 1226
  2363. The Clinical Application ofย Rapamycinย Eluting Stent in Elderly Patients with Coronary Heart Disease.
  2364. Rapamycinย induced โ€œstunningโ€ on FDG PET/CT in pancreatic cancer
  2365. Protective Effect of Pretreatedย Rapamycinย on Renal Ischemia-Reperfusion Injury in Rats
  2366. Rapamycinย impairs skin ฮณฮด T cell function resulting in autophagy
  2367. Rapamycinย aggravates the renal damage in rats with protein overload nephropathy and the protection of losartan
  2368. Observation in Safety and Short-term Efficacy of Domestic-madeย Rapamycin-eluting Stent
  2369. Rapamycinย Treatment Exacerbates Nutrition-Induced Diabetes in Psammomys obesus.
  2370. Rapamycinโ€sensitiveย inhibitionย of Id1 and p21 in C2C12 myoblasts
  2371. Effects ofย Rapamycinย on the Liver Regeneration after Partial Hepatectomy in Rats
  2372. Statin therapy, alone or in combination withย Rapamycin, does not reverse Monocotaline Pulmonary Arterial Hypertension
  2373. Comparative study on clinical outcomes of two kinds of Chineseย Rapamycin-eluting stent in patients with coronary artery disease
  2374. Rapamycinย rescues lactacystin-induced dopaminergic neuron injury in vivo
  2375. Modulation of cell cycle progression by combinedย Rapamycin-octreotide treatment in pituitary tumor cells
  2376. Local application ofย Rapamycinย inhibits neointimal hyperplasia in experimental vein grafts
  2377. Histologic Changes After Intravitreal Injection ofย Rapamycinย and Bevacizumab in a Porcine Model
  2378. Bevacizumab andย Rapamycinย induce growth suppression in mouse models of hepatocellular carcinoma
  2379. Study on the activation of mammalian target ofย Rapamycinย in two endometrial carcinoma cells
  2380. Study on the changes of mammalian target ofย Rapamycinย with aging in rat kidneys
  2381. 290:ย Rapamycin-generated Th2 cell therapy of established acute murine GVHD requires Th2 cell secretion of both IL-4 and IL-10
  2382. Rapamycinย CAN AMELIORATE CAN IN RAT ALLOGRAFTS BY AFFECTING RHO/ROCK SIGNAL PATHWAY: 2147
  2383. Clinical study on major adverse cardiac events (MACE) rate in patients implanted withย Rapamycin-eluting stents [J]
  2384. Preclinical evaluation of sorafenib in combination withย Rapamycinย for the treatment of acute myeloid leukemia (AML)
  2385. The Development and Molecular Expression in Mammalian Cells of an HA-Tagged Plasmid Encoding for the Target Ofย Rapamycinย (mTOR)
  2386. The Role of Mammalian Target ofย Rapamycinย (mTOR) Inhibitors in the Treatment of Solid Tumors
  2387. INFLUENCE OFย Rapamycinย ON RENAL TUBULAR FUNCTION IN RATS WITH OR WITHOUT CYCLOSPORINE TREATMENT: 1938
  2388. Drug eluting stents: long term results in clinical practice. Comparison betweenย Rapamycinย and paclitaxel eluting stents
  2389. Nucleophosmin Mediates Mammalian Target ofย Rapamycin
  2390. Rapamycinย inhibits activation of Stat3 in kidney tissue of IgA nephropathy rats
  2391. Leukemia Induced by Altered TRK-Signaling Is Sensitive toย Rapamycinย Treatment in a Preclinical Model
  2392. Mechanisms of urokinase mediated activation of the mammalian target ofย Rapamycinย (mTOR)
  2393. UROKINASEโ€INDUCED SMOOTH MUSCLE CELL MIGRATION INVOLVES THE MAMMALIAN TARGET OFย Rapamycin
  2394. Anti-inflammatory properties ofย Rapamycinย on leukocyte-endothelial cell interactions following profound hypoperfusion
  2395. Contrasting effects of Cyclosporine andย Rapamycinย in de novo generation of alloantigen-specific regulatory T cells (88.45)
  2396. Combination treatment ofย Rapamycinย and low dose irradiation causes cell death in human cancer cells cultured as 3-D spheroids
  2397. Rapamycinย effects onย mTORย signaling in the MCF10AT series of human breast epithelial cells: a model for proliferative breast disease and carcinoma
  2398. Anti-inflammatory drugs, sirolimus, andย inhibitionย of target ofย Rapamycinย and its effect on vascular diseases
  2399. Effect ofย Rapamycinย in inducing naรฏve murine effector T cell convert to regulatory T cell
  2400. A high throughput assay for mammalian target ofย Rapamycinย (mTOR) kinase activity
  2401. Rapamycinย INDUCES AUTOPHAGY IN ISLETS: RELEVANCE FOR ISLETS TRANSPLANTATION: 556
  2402. Angioplasty stenting with Sirolimus (Rapamycin) eluting stents in type 2 diabetic patients
  2403. The Immunosuppressive drugsย Rapamycinย and FK506 decrease vasodilation by increasing PKCbetaiโ€mediated phosphorylation of eNOS Thr495
  2404. Rapamycinย inhibitionย of the Akt/mTORย pathway blocks select stages of VEGF-A driven angiogenesis in part through the blockade of S6Kinase
  2405. Combinedย Rapamycin-octreotide treatment exerts its superior antiproliferative action by dramatically increasing p27/Kip1 expression
  2406. Characterisation of a novel and highly selective kinase inhibitor of the mammalian target ofย Rapamycinย (mTOR)
  2407. ST2L upregulation promotes maturation resistance inย Rapamycinโ€conditioned dendritic cells
  2408. P286: Mechanisms of urokinase mediated activation of the mammalian target ofย Rapamycinย (mTOR)
  2409. Akt phosphorylates and negatively regulates hnRNPA1-mediated control of cyclin D1 and c-myc translation in response toย Rapamycin
  2410. Intravitrealย Rapamycinย and Bevacizumab Inhibits VEGF Expression in a Swine Model of Neovascularization
  2411. Acute activation of the mammalian target ofย Rapamycinย complex 1 does not impair in vivo insulin action in mice
  2412. Combined Therapeutic Effects of Vinblastine andย Rapamycinย on Human Neuroblastoma Growth, Apoptosis, and Angiogenesis
  2413. Cell cycle proteins and hTERT telomerase mRNA expression are independent targets ofย Rapamycinย in ovarian cancer cell lines
  2414. Re-evaluating the roles of proposed modulators of mammalian target ofย Rapamycinย complex 1 (mTORC1) signaling
  2415. P39.ย Rapamycinย and the downstream target ofย mTOR, ribosomal protein L29 (RPL29), regulate prostate cancer cell growth and bone metastatic potential
  2416. Thymidine phosphorylase-related migratory effect of cancer cell is abrogated by m-TOR inhibitorย Rapamycin
  2417. Curcuminย inhibitionย of the mammalian target ofย Rapamycinย signaling pathway
  2418. Synergistic combinations of a novel PI3 Kinase inhibitor with Erlotinib andย Rapamycinย and the associated effects on downstream signalling
  2419. Evaluation of the mTOT inhibitor,ย Rapamycinย in dogs with spontaneously derived osteosarcoma: A focus on preclinical pharmacokinetics and pharmacodynamics
  2420. Activation of Mammalian Target ofย Rapamycinย (mTOR) in Esophageal Squamous Cell Carcinona Cell Line [J]
  2421. The mammalian target ofย Rapamycinย (mTOR) signaling in thymic lymphomagenesis in Atm-/-mice
  2422. Rapamycin-induced remission of Kaposiโ€™s sarcoma is not associated with expansion of cytotoxic T-lymphocyte subsets
  2423. The Mammalian Target ofย Rapamycinย Plays a Critical Role in the Development of Cardiac Hypertrophy in Spontaneously Hypertensive Rats
  2424. Inhibitory effect ofย Rapamycinย and dexamethasone on production of IL-17 and IFN-c in Vogtโ€“Koyanagiโ€“Harada patients
  2425. Targeted therapy for osteosarcoma using 17AAG andย Rapamycin: Identification of new targets by gene microarray profiling and miRNA
  2426. Divergent Roles of PI3K and Akt inย Rapamycin-induced Cardioprotection against Ischemia-Reperfusion Injury
  2427. The Combination of theย mTORย Inhibitorย Rapamycinย and Protein Kinase C Inhibitors Produces Marked Synergistic Anti-Myeloma Effects.
  2428. Expansion of Functional Polyclonal Human T-regulatory Cell Lines Using Artificial Antigen Presenting Cells andย Rapamycin.(B159)
  2429. Sepsis associated platelet dysfunction &ย Rapamycinย sensitive pathway of lipopolysaccharide signaling
  2430. COMPARISON OFย Rapamycinย VS. FK506 ON EXPRESSION OF CYTOPROTECTIVE GENES IN THE RAT-KIDNEY ALLOGRAFTS UNDERGOING CHRONIC โ€ฆ
  2431. Synergistic effect ofย Rapamycinย and Casodex inย inhibitionย of cell growth and survival as well as AR transcriptional activity in androgen dependent and independent โ€ฆ
  2432. Clenbuterol antagonizesย Rapamycin-induced atrophy in rat soleus muscle
  2433. Ocular Toxicity and Distribution of Intravitreal and Subconjunctivalย Rapamycinย in Horses
  2434. Rapamycinย Withdrawal versus Delayed Initiation: Thrombosis vs. Suppression of Neointimal Hyperplasia after Vascular Injury
  2435. Rapamycinย prevents cadmium-induced neuronal apoptosis by suppression of MAPK andย mTORย pathways
  2436. Changes in gene expression profile afterย Rapamycinย treatment of ErbB2-positive/ErbB2-negative breast carcinoma in organ culture
  2437. Dualย inhibitionย of the Akt pathway byย Rapamycinย and Perifosine induces synergistic anti-tumor activity in multiple myeloma
  2438. Clinical Benefits ofย Rapamycin-Eluting Stent Made in China Appliance and Investigation in Patients with Acute Coronary Syndromes
  2439. Rapamycinย Causes Reversible Cell Cycle Slowing, Rather Than Cell Cycle Arrest, in Myeloid and Lymphoid Cell Lines and in Acute Leukemia Cells
  2440. Effectiveย inhibitionย of tumor growth in patient-derived xenografts of hepatocellular carcinoma byย Rapamycinย and bevacizumab
  2441. Protein kinase C (ฮผ, ฮธ, ฯต)-dependent Bad phosphorylation is an important signaling pathway in IGF-I rescue of sarcoma cells fromย Rapamycin-induced apoptosis
  2442. Enzastaurin inhibits growth of head and neck cancer cells and xenografts and synergizes withย Rapamycin
  2443. Binding of novelย Rapamycinย analogs to calcium channels and FKBP52 contributes to their neuroprotective activities
  2444. Combination of somatostatin analogues withย Rapamycinย analogues as a potential pharmaceutical treatment for non-functioning pituitary adenomas
  2445. Mammalian Target ofย Rapamycinย (mTOR) is Essential for Murine Heart Development
  2446. A spontaneous pancreatic tumor model for monitoring pancreatic lesion and response toย Rapamycinย treatment through bioluminescence imaging
  2447. Targeted therapy for osteosarcoma using 17AAG andย Rapamycin: Identification of new targets using Gene Microarray profiling and MiRNA
  2448. Rapamycinย regulates synthesis of transforming growth factor-beta1 and extracellular matrix in arterial neointimal smooth muscle cells
  2449. Utilization of Meso Scale Discovery ELISA technology to quantitate the in vivo pharmacodynamic effects ofย Rapamycinย treatment on the AKT pathway
  2450. Rapamycinย blocks leucineโ€induced protein synthesis by suppressingย mTORC1 activation in skeletal muscle of neonatal pigs
  2451. Rapamycinย IS LESS FIBROGENIC THAN FK506 IN RAT MODEL OF CHRONIC ALLOGRAFT NEPHROPATHY: 2144
  2452. Identification and characterization of novel positive regulators of the Target ofย Rapamycinย (TOR) pathway in Drosophila melanogaster
  2453. The Role of Mammalian Target ofย Rapamycinย in the Regulation of Amino Acid Transporters in the Human Placenta
  2454. Rapamycin,ย mTORย inhibitor, a potent inhibitor for the cell growth and proliferation by p21-dependent mitotic arrest in human gastric cancers
  2455. Role of mechanistic Target ofย Rapamycinย (mTOR) signaling in the crustacean molting gland
  2456. โ€ฆ Scale Expansion of Human Dendritic Cells with Regulatory Function from Peripheral Blood Monocytes Employing Leukapheresis andย Rapamycinย for Clinical Trials.
  2457. Angioplasty stenting with Sirolimus (Rapamycin) eluting stents in type 2 diabetic patients Angioplastia con stents liberadores de rapamicina en diabรฉticos tipo 2 โ€ฆ
  2458. Rapamycinย prevents tobacco-carcinogen induced lung tumorigenesis and selectively reduces lung-associated Foxp3 positive cells
  2459. Clinical observation ofย Rapamycinย Eluting Stent in acute ST-segment elevated myocardial infarction between domestic and imported product
  2460. Targeted therapy for osteosarcoma using 17AAG andย Rapamycin: identification of new targets using l Gene microarray profiling and proteomics
  2461. EARLY IMMUNOSUPPRESSION WEANING AFTER CADAVER LIVER TRANSPLANTATION USING ATG INDUCTION ANDย Rapamycin: 358
  2462. inhibitionย effect ofย Rapamycinย on acute graft-versus-host disease after allogeneic bone marrow transplantation in a murine model
  2463. Dualย inhibitionย of phosphoinositide 3-kinase and mammalian target ofย Rapamycinย as a novel therapeutic approach in human ovarian carcinoma
  2464. A small molecule inhibitor against kinase domain of mammalian target ofย Rapamycinย (mTOR) causes autophagic cell death in glioblastoma
  2465. Effects of Imatinib andย Rapamycinย on theย mTOR/S6 Signal Transduction Pathway in CD33+ Cell of CML
  2466. mTORย inhibitorsย Rapamycinย and RAD001 (Everolimus) induce antiproliferative effects in GH3 cell line and human pituitary adenomas
  2467. PNEUMONITIS FROM INHIBITORS OF THE MAMMALIAN TARGET OFย Rapamycinย (mTOR) IN PATIENTS WITH METASTATIC CANCER
  2468. Targeted therapy for osteosarcoma using 17AAG andย Rapamycin: Characterization of induced apoptosis andย inhibitionย ofย mTORย and AKT/MAP kinase pathways
  2469. Blockage ofย mTORย signaling pathway byย Rapamycinย contributes toย inhibitionย of tumor cell proliferation in ALK-positive lymphoid cell strains
  2470. The Yaa locus Confers Apoptosis, NF-ฮบB andย Rapamycinย Signaling Resistance Through Multiple Receptors in C57BL/6J Mice (129.12)
  2471. Domestic versus foreignย Rapamycin-eluting stents for emergency percutaneous coronary intervention in elder patients with acute myocardial infarction: Randomized โ€ฆ
  2472. Tumor suppressor gene ARHI (DIRAS3) is required for spontaneous andย Rapamycin-induced autophagy in normal and ovarian cancer cells
  2473. Complete Responses in Patients with Autoimmune Lymphoproliferative Syndrome (ALPS) Using theย mTORย Inhibitor Sirolimus (Rapamycin)
  2474. Signaling Downstream of Mammalian Target ofย Rapamycinย Complex 1 (mTORC1) is Derepressed Following Treatment with Lโ€Asparaginase in the Liver of GCN2 โ€ฆ
  2475. MESENCHYMAL STEM CELLS ATTENUATE ACUTE REJECTION AND SYNERGIZE WITHย Rapamycinย LEADING TO CARDIAC ALLOGRAFT TOLERANCE: 382
  2476. inhibitionย of the mammalian target ofย Rapamycinย (mTOR) for the chemoprevention of tobacco-carcinogen induced lung tumorigenesis
  2477. mTORC1ย inhibitionย withย Rapamycinย or LY294002 alone but not in combination leads to AKT phosphorylation viaย mTORC2 in melanoma cells
  2478. Corrigendum to โ€œLow-dose oralย Rapamycinย treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosisโ€[J โ€ฆ
  2479. FK506 VERSUSย Rapamycinย HAVE DIFFERENT EFFECTS ON EXPRESSION OF ANGIOPOIETINS1, 2 AND TIE2 IN RAT RENAL ALLOGRAFT WITH CAN: 1925
  2480. Combination Therapy Utilizing Murine Anti-Thymocyte Globulin (ATG) andย Rapamycinย for the Reversal of Overt Type 1 Diabetes in NOD Mice.
  2481. Rapamycinย REDUCES VASCULAR INJURY BUT EXACERBATES PROTEINURIA IN ASSOCIATION WITHย inhibitionย OF VEGF AND VEGF-R IN CHRONIC โ€ฆ
  2482. โ€ฆ Inhibitor Causes Growthย inhibition, Cell Cycle Arrest, Apoptosis and Autophagic Cell Death in Mantle Cell Lymphoma Cell Lines: A Distinct Profile fromย Rapamycin.
  2483. Rapamycinย PREFERENTIALLY BLOCKS THE EXPANSION OF POTENTIALLY TOLEROGENIC PLASMACYTOID DENDRITIC CELLS IN VIVO: 2217
  2484. Rapamycinย DECREASES CHOLESTEROL EFFLUX AND ABCA1 PROTEIN EXPRESSION WITHIN THP-1 MACROPHAGES: 1931
  2485. TARGETED DELIVERY OFย Rapamycinย TO DENDRITIC CELLS USING BIODEGRADABLE MICROPARTICLES IS HIGHLY EFFECTIVE IN SUPPRESSING THEIR โ€ฆ
  2486. Mating Stimulates Protein Phosphorylation and Synthesis Viaย Rapamycin-and Wortmannin-Sensitive Pathways in the Male Accessory Glands of D. melanogaster
  2487. Dietary induced insulin resistance is independent of mammalian target ofย Rapamycinย complex 1 (mTORC1) activity in skeletal muscle of mice
  2488. 191:ย Rapamycinย inhibits endothelial cell recovery after hypoxic injury
  2489. Enhancement of Mammalian Target ofย Rapamycinย Complex-2 (TORC2) Kinase Activity by Fructose-2, 6-Bisphosphate.
  2490. Effect ofย Rapamycin/Curcumin Co-Loaded Poly (Lactide-Co-Glycolide) Films on Blood Compatibility and Vascular Smooth Muscle Cell Proliferation
  2491. COMBINE TGF-BETA/FC ANDย Rapamycinย FOR REGULATORY T CELLS GENERATION AND ALLOGRAFT TOLERANCE INDUCTION.: 728
  2492. The Wnt Agonist, SKL2020 Inhibits Neointimal Hyperplasia but Facilitates Re-Endothelialization, When Treated withย Rapamycinย in Porcine Coronary Artery Stent โ€ฆ
  2493. IL-1ฮฒ-DRIVEN ST2 EXPRESSION PROMOTES MATURATION RESISTANCE INย Rapamycin-CONDITIONED DENDRITIC CELLS: 643
  2494. PRO-TOLEROGENIC PROPERTIES OFย Rapamycinย THAT FAVOR INDEFINITE HEART ALLOGRAFT SURVIVAL MEDIATED BY REGULATORY T CELLS.: 27
  2495. Mechanism of luteolin-induced apoptosis through suppressing p21 (WAF1/CIP1) expression withย Rapamycinย in HER2-overexpressing cancer cells
  2496. โ€ฆ ALLOGRAFT SURVIVAL IN UNMANIPULATED HOSTS BY POST-TRANSPLANT INFUSION OF DONOR-SPECIFIC REGULATORY T CELLS ANDย Rapamycin: 655
  2497. Role of the mammalian Target ofย Rapamycinย (mTOR) Complex 1 signaling in betaโ€adrenergicโ€stimulated triacylglycerol (TAG) lipolysis and free fatty acid (FFA) โ€ฆ
  2498. A phase I study of theย mTORย inhibitor sirolimus (Rapamycin) in combination with nanoparticle albumin-bound paclitaxel (ABI-007, abraxane) in advanced solid cancers
  2499. IMPACT OF IMMUNOSUPPRESSION ON UV-INDUCED SKIN-TUMORS IN MICE:ย Rapamycinย IMPAIRS TUMOR OUTGROWTH AND SHIFTS THE MUTATION โ€ฆ
  2500. Dexamethasone represses signaling through mammalian target ofย Rapamycinย (mTOR) in muscle cells by enhancing expression of REDD1
  2501. inhibitionย of mammalian target ofย Rapamycinย (mTOR) induces phosphatidylinositol 3 kinase-dependent and Mnk-mediated eIF4E phosphorylation
  2502. Rapamycin,ย mTORย Inhibitor, a Potent Cell Growth and Proliferation Inhibitor by p21-Dependent Mitotic Arrest in Human Gastric Cancers
  2503. Rapamycinย PROMOTES THE ENRICHMENT OF CD4+ CD25HIFOXP3+ T REGULATORY CELLS FROM NAIVE CD4+ T CELLS OF BABOON THAT SUPPRESS โ€ฆ
  2504. โ€ฆ with drug eluting stents but with significant cost saving: long term follow up results from the randomized, controlled ORAR III (Oralย Rapamycinย in Argentina) Study
  2505. PD2-4 Survival Advantage of Temsirolimus Validates a Role for Mammalian Target ofย Rapamycinย (mTOR) in the Biology of Advanced Renal Cell Carcinoma
  2506. P3-026: A novel Bayesian dose-escalation Phase Ib study design investigating combination of the mammalian target ofย Rapamycinย (mTOR) inhibitor RAD001 with โ€ฆ
  2507. Cell cycle arrest and suppression of the Akt/mammalian target ofย Rapamycinย signaling mediated by yuanhuadine, a daphnane diterpenoid, isolated from Daphne โ€ฆ
  2508. โ€ฆ Smooth Muscle Cell Proliferation and Intimal Expansion by Phosphatidylinositol 3-Kinaseโ€“Dependent Mammalian Target ofย Rapamycinย Raptor Complex 1 โ€ฆ
  2509. 155. Tumor Necrosis In Vivo Caused by a Novel Combination of Sorafenib andย Rapamycin: Targeting the RAS and Motor Pathways ION Hepatocellular Carcinoma
  2510. 342:ย Rapamycinย Prevents GVHD in Mouse Model through Novel Mechanism: Increase in Regulatory T cells
  2511. โ€ฆ downregulates acetyl-CoA carboxylase alpha and fatty acid synthase by activating AMP-activated protein kinase and suppressing the mammalian target ofย Rapamycinย โ€ฆ
  2512. Glycogen Synthase Kinase-3 (GSK-3) Signaling to Mammalian Target ofย Rapamycinย (mTOR) Regulates DNA Synthesis and Cell Cycle Progression in Rodent and โ€ฆ
  2513. THROMBOSPONDIN-1 (TSP-1) MEDIATES THE ANTI ANGIOGENIC AND IMMUNOMODULATORY EFFECTS OFย Rapamycinย ON PANCREATIC ISLET โ€ฆ
  2514. 53:ย Rapamycinย Partially Overcomes the in vitro Protective Effect of M2โ€“10B4 Mesenchymal Stromal Cells (MSC) to Murine mCGPR/+ Acute Promyelocytic Leukemic โ€ฆ
  2515. โ€ฆ CXC Chemokine Receptor 4 (CXCR4) by Hypoxia and the Phosphatidylinositol 3โ€Kinase (PIโ€3โ€K)/Mammalian Target ofย Rapamycinย (mTOR) Signaling Pathway
  2516. 234:ย Rapamycinย generated donor Th2/Tc2 cells prevent graft rejection byย inhibitionย of alloreactivity and not by deletion of alloreactive T cells
  2517. FoxP3 Mediated Induction of Pim 2 Allows T Regulatory Cells to Preferentially Expand inย Rapamycin
  2518. The Novel Glycolysis Inhibitor, 3-BrOP, Has Broad Activity Against Acute Lymphoblastic Leukemias and Potentiates Methotrexate andย Rapamycin.
  2519. โ€ฆ -selective oncolytic adenovirus OBP-405 induces autophagic cell death and enhances the antitumor effect of temozolomide andย Rapamycinย on glioblastoma cells in โ€ฆ
  2520. โ€ฆ regulatory (CD4+ CD25+ CD127LowFOXP3+) cells to high purity by inhibiting expansion of CD4+ CD25+ CD127HighFOXP3-conventional T cells withย Rapamycin
  2521. Late stage efficacy and regulated gene expression profiles by 5-aza-dC, valproic acid, suberoylanilide hydroxamic acid, andย Rapamycinย in mouse lung tumorigenesis
  2522. 720:ย inhibitionย of Proliferation byย Rapamycinย in RAT Bladder Smooth Muscle Cells
  2523. 307: Initial selection of high affinity CD25+ cells increases the purity of CD4+ CD25+ Foxp3+ T regulatory cells expanded in medium containingย Rapamycin
  2524. 518: Medium term renal function of pediatric heart transplant patients on reduced calcineurin inhibitor andย Rapamycin
  2525. Automated quantitative analysis of AKT/mTORย pathway in patients treated with nanoparticle albumin-bound paclitaxel (ABI-007, Abraxane) and (sirolimus)ย Rapamycin
  2526. 51:ย Rapamycinย and its influence on arterial vascular function after short-term incubation
  2527. 336: Relative Contribution of CD127 Negative Selection,ย Rapamycin, and TGF-ฮฒ to the Generation of Human Regulatory T Cells that Inhibit Alloreactivity via Dendritic โ€ฆ
  2528. An ATP-competitive mammalian target ofย Rapamycinย inhibitor revealsย Rapamycin-resistant functions ofย mTORC1
  2529. Rapamycinย decelerates cellular senescence
  2530. Structure of the humanย mTORย complex I and its implications forย Rapamycinย inhibition
  2531. Delayed correlation of mRNA and protein expression inย Rapamycin-treated cells and a role for Ggc1 in cellular sensitivity toย Rapamycin
  2532. Rapamycinย inhibitsย mTORC1, but not completely
  2533. Mammalian target ofย Rapamycin: discovery ofย Rapamycinย reveals a signaling pathway important for normal and cancer cell growth
  2534. Rapamycinย ameliorates PKD resulting from conditional inactivation of Pkd1
  2535. Rapamycinย fed late in life extends lifespan in genetically heterogeneous mice
  2536. Mechanisms of life span extension byย Rapamycinย in the fruit fly Drosophila melanogaster
  2537. Rapamycinย Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinsonโ€™s Disease
  2538. Targetingย mTORย withย Rapamycin: one dose does not fit all
  2539. The role of the mammalian target ofย Rapamycinย (mTOR) in renal disease
  2540. Mammalian target ofย Rapamycinย (mTOR): conducting the cellular signaling symphony
  2541. Potential use ofย Rapamycinย in HIV infection
  2542. Targetingย mTORย globally in cancer: thinking beyondย Rapamycin
  2543. The complexes of mammalian target ofย Rapamycin
  2544. The mammalian target ofย Rapamycin: linking T cell differentiation, function, and metabolism
  2545. Not all substrates are treated equally: Implications forย mTOR,ย Rapamycin-resistance, and cancer therapy
  2546. Rapamycin-induced phosphaturia
  2547. The mammalian target ofย Rapamycinย signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy
  2548. Mammalian target ofย Rapamycinย complex 1: signalling inputs, substrates and feedback mechanisms
  2549. Rapamycinย administration in humans blocks the contractionโ€induced increase in skeletal muscle protein synthesis
  2550. Rapamycinย extends maximal lifespan in cancer-prone mice
  2551. Active-site inhibitors ofย mTORย targetย Rapamycin-resistant outputs ofย mTORC1 andย mTORC2
  2552. Nutrient-dependent regulation of autophagy through the target ofย Rapamycinย pathway
  2553. Biosynthesis ofย Rapamycinย and its regulation: past achievements and recent progress
  2554. inhibitionย ofย mTORย byย Rapamycinย abolishes cognitive deficits and reduces amyloid-ฮฒ levels in a mouse model of Alzheimerโ€™s disease
  2555. SIRT1 negatively regulates the mammalian target ofย Rapamycin
  2556. Targeting mammalian target ofย Rapamycinย byย Rapamycinย prevents tumor progression in an oral-specific chemical carcinogenesis model
  2557. Characterization of theย Rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis
  2558. Rapamycinย and quasi-programmed aging: Four years later
  2559. A versatile role of mammalian target ofย Rapamycinย in human dendritic cell function and differentiation
  2560. Autophagy is required for extension of yeast chronological life span byย Rapamycin
  2561. Rapid inactivation of proteins byย Rapamycin-induced rerouting to mitochondria
  2562. Discovery of GSK2126458, a highly potent inhibitor of PI3K and the mammalian target ofย Rapamycin
  2563. Ku-0063794 is a specific inhibitor of the mammalian target ofย Rapamycinย (mTOR)
  2564. Rapamycinย activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
  2565. GOLPH3 modulatesย mTORย signalling andย Rapamycinย sensitivity in cancer
  2566. Molecular interplay between mammalian target ofย Rapamycinย (mTOR), amyloid-ฮฒ, and Tau: effects on cognitive impairments
  2567. Aย Rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states
  2568. Resveratrol andย Rapamycin: are they antiโ€aging drugs?
  2569. Metformin andย Rapamycinย have distinct effects on the AKT pathway and proliferation in breast cancer cells
  2570. Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target ofย Rapamycin
  2571. Rapamycinย protects against rotenone-induced apoptosis through autophagy induction
  2572. Protein synthesis is resistant toย Rapamycinย and constitutes a promising therapeutic target in acute myeloid leukemia
  2573. Rapamycinย reduces seizure frequency in tuberous sclerosis complex
  2574. Pharmacologicalย inhibitionย of the mammalian target ofย Rapamycinย pathway suppresses acquired epilepsy
  2575. Preliminary characterization of oral lesions associated with inhibitors of mammalian target ofย Rapamycinย in cancer patients
  2576. TORC-specific phosphorylation of mammalian target ofย Rapamycinย (mTOR): phospho-Ser2481 is a marker for intactย mTORย signaling complex 2
  2577. Total synthesis ofย Rapamycin
  2578. Targetedย inhibitionย of mammalian target ofย Rapamycinย signaling inhibits tumorigenesis of colorectal cancer
  2579. AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target ofย Rapamycinย kinase inhibitor with in vitro and in vivo antitumor activity
  2580. Tti1 and Tel2 are critical factors in mammalian target ofย Rapamycinย complex assembly
  2581. Theย mTORย pathway is highly activated in diabetic nephropathy andย Rapamycinย has a strong therapeutic potential
  2582. Role for mammalian target ofย Rapamycinย complex 1 signaling in neuroadaptations underlying alcohol-related disorders
  2583. Dualย inhibitionย of Akt/mammalian target ofย Rapamycinย pathway by nanoparticle albumin-boundโ€“Rapamycinย and perifosine induces antitumor activity in multiple โ€ฆ
  2584. Long-termย Rapamycinย therapy in the Han: SPRD rat model of polycystic kidney disease (PKD)
  2585. Delivery ofย Rapamycinย to dendritic cells using degradable microparticles
  2586. Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib andย Rapamycinย in vivo
  2587. CDC25B mediatesย Rapamycin-induced oncogenic responses in cancer cells
  2588. Regulation ofย mTORC1 andย mTORC2 complex assembly by phosphatidic acid: competition withย Rapamycin
  2589. Curcumin disrupts the Mammalian target ofย Rapamycin-raptor complex
  2590. HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 andย Rapamycinย combination therapy
  2591. Chronicย Rapamycinย treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose โ€ฆ
  2592. Recent advances in the chemistry, biosynthesis and pharmacology ofย Rapamycinย analogs
  2593. inhibitionย of target ofย Rapamycinย signaling and stress activate autophagy in Chlamydomonas reinhardtii
  2594. Akt signals through the mammalian target ofย Rapamycinย pathway to regulate CNS myelination
  2595. Beneficial effects of Mammalian target ofย Rapamycinย inhibitionย on left ventricular remodeling after myocardial infarction
  2596. Mammalian target ofย Rapamycinย protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways
  2597. Activation of the mammalian target ofย Rapamycinย (mTOR) is essential for oligodendrocyte differentiation
  2598. Theย Rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates
  2599. Sorafenib andย Rapamycinย induce growth suppression in mouse models of hepatocellular carcinoma
  2600. Mammalian target ofย Rapamycin: hitting the bullโ€™s-eye for neurological disorders
  2601. Rapamycinย andย mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
  2602. Mammalian target ofย Rapamycinย (mTOR)ย inhibitionย as a potential antiepileptogenic therapy: from tuberous sclerosis to common acquired epilepsies
  2603. inhibitionย of the mammalian target ofย Rapamycinย (mTOR) in advanced pancreatic cancer: results of two phase II studies
  2604. A pharmacodynamic study ofย Rapamycinย in men with intermediate-to high-risk localized prostate cancer
  2605. Bone growth duringย Rapamycinย therapy in young rats
  2606. Regulation of placental amino acid transporter activity by mammalian target ofย Rapamycin
  2607. Rapamycinย inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity
  2608. Mammalian target ofย Rapamycinย regulates miRNA-1 and follistatin in skeletal myogenesis
  2609. Topicalย Rapamycin: a novel approach to facial angiofibromas in tuberous sclerosis
  2610. New inhibitors of the mammalian target ofย Rapamycinย signaling pathway for cancer
  2611. Cutting edge:ย Rapamycinย augments pathogen-specific but not graft-reactive CD8+ T cell responses
  2612. Mammalian target ofย Rapamycinย inhibitors and their potential role in therapy in leukaemia and other haematological malignancies
  2613. Integration of general amino acid control and target ofย Rapamycinย (TOR) regulatory pathways in nitrogen assimilation in yeast
  2614. Specific roles of Target ofย Rapamycinย in the control of stem cells and their progeny in the Drosophila ovary
  2615. Down-regulation of Akt/mammalian target ofย Rapamycinย signaling pathway in response to myostatin overexpression in skeletal muscle
  2616. Infusion of mesenchymal stem cells andย Rapamycinย synergize to attenuate alloimmune responses and promote cardiac allograft tolerance
  2617. Rapamycinย suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia
  2618. Rapamycinย inhibitionย of the Akt/mTORย Pathway Blocks Select Stages of VEGF-A164โ€“Driven Angiogenesis, in Part by Blocking S6Kinase
  2619. Rapamycinย Protects Against High Fat Dietโ€“Induced Obesity in C57BL/6J Mice
  2620. Rapamycinย regulates stearoyl CoA desaturase 1 expression in breast cancer
  2621. Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect ofย Rapamycinย in neonatal hypoxia-ischemia
  2622. Overexpression of phosphorylated mammalian target ofย Rapamycinย predicts lymph node metastasis and prognosis of chinese patients with gastric cancer
  2623. Mammalian target ofย Rapamycinย (mTOR) activation increases axonal growth capacity of injured peripheral nerves
  2624. Rapamycinย promotes ฮฒ-amyloid production via ADAM-10ย inhibition
  2625. Differential responses of human regulatory T cells (Treg) and effector T cells toย Rapamycin
  2626. Monitoring mammalian target ofย Rapamycinย (mTOR) activity
  2627. The efficacy of the novel dual PI3-kinase/mTORย inhibitor NVP-BEZ235 compared withย Rapamycinย in renal cell carcinoma
  2628. Mammalian target ofย Rapamycinย is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats
  2629. Treatment withย Rapamycinย prevents fibrosis in tightโ€skin and bleomycinโ€induced mouse models of systemic sclerosis
  2630. Mammalian target ofย Rapamycinย complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage
  2631. Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target ofย Rapamycinย (TOR) pathway
  2632. Mammalian target ofย Rapamycinย controls dendritic cell development downstream of Flt3 ligand signaling
  2633. Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target ofย Rapamycinย pathway
  2634. Longโ€term administration ofย Rapamycinย reduces adiposity, but impairs glucose tolerance in highโ€fat dietโ€fed KK/HlJ mice
  2635. Rapamycinย inhibits hepatic fibrosis in rats by attenuating multiple profibrogenic pathways
  2636. Regulation of insulin-like growth factorโ€“mammalian target ofย Rapamycinย signaling by microRNA in childhood adrenocortical tumors
  2637. Rapamycinย prevents transforming growth factor-ฮฑโ€“induced pulmonary fibrosis
  2638. Participation of mammalian target ofย Rapamycinย complex 1 in Toll-like receptor 2โ€“and 4โ€“induced neutrophil activation and acute lung injury
  2639. Use ofย Rapamycinย in the induction of tolerogenic dendritic cells
  2640. Rapamycinย versus methotrexate in early diffuse systemic sclerosis: Results from a randomized, singleโ€blind pilot study
  2641. Insights into the domain and repeat architecture of target ofย Rapamycin
  2642. A novel mouse model of inflammatory bowel disease links mammalian target ofย Rapamycin-dependent hyperproliferation of colonic epithelium to inflammation โ€ฆ
  2643. Nutrient availability and lactogenic hormones regulate mammary protein synthesis through the mammalian target ofย Rapamycinย signaling pathway
  2644. The mammalian target ofย Rapamycinย as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system
  2645. โ€ฆ irinotecan andย Rapamycinย combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target ofย Rapamycinย โ€ฆ
  2646. Rapamycinย rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability
  2647. Rapamycin-resistantย mTORC1 kinase activity is required for herpesvirus replication
  2648. Mammalian target ofย Rapamycinย regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade
  2649. Celastrol suppresses angiogenesis-mediated tumor growth throughย inhibitionย of AKT/mammalian target ofย Rapamycinย pathway
  2650. Critical roles forย mTORC2-andย Rapamycin-insensitiveย mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells
  2651. inhibitionย of the mammalian target ofย Rapamycinย signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy
  2652. Oralย Rapamycinย attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels
  2653. Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy withย Rapamycin
  2654. inhibitionย of histone deacetylase overcomesย Rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling throughย mTORC2
  2655. Rapamycinย promotes the osteoblastic differentiation of human embryonic stem cells by blocking theย mTORย pathway and stimulating the BMP/Smad pathway
  2656. Synergistic effect ofย Rapamycinย and cisplatin in endometrial cancer cells
  2657. Activation of mammalian target ofย Rapamycinย controls the loss of TCRฮถ in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation
  2658. Mammalian target ofย Rapamycinย activation underlies HSC defects in autoimmune disease and inflammation in mice
  2659. Uremic cardiac hypertrophy is reversed byย Rapamycinย but not by lowering of blood pressure
  2660. Testosterone induces cardiomyocyte hypertrophy through mammalian target ofย Rapamycinย complex 1 pathway
  2661. Rapamycinย in islet transplantation: friend or foe?
  2662. Mammalian target ofย Rapamycinย complex 1 (mTORC1) activity is associated with phosphorylation of raptor byย mTOR
  2663. Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs
  2664. Mammalian target ofย Rapamycinย signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis
  2665. Rapamycinย has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage?
  2666. Distinct roles for mammalian target ofย Rapamycinย complexes in the fibroblast response to transforming growth factor-ฮฒ
  2667. Expression of an activated mammalian target ofย Rapamycinย (mTOR) in gastroenteropancreatic neuroendocrine tumors
  2668. The somatostatin analogue octreotide confers sensitivity toย Rapamycinย treatment on pituitary tumor cells
  2669. Rapamycinย regulates Akt and ERK phosphorylation throughย mTORC1 andย mTORC2 signaling pathways
  2670. Rapamycinย potentiates the effects of paclitaxel in endometrial cancer cells throughย inhibitionย of cell proliferation and induction of apoptosis
  2671. ATP-competitive inhibitors of the mammalian target ofย Rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines
  2672. Gastric mammalian target ofย Rapamycinย signaling regulates ghrelin production and food intake
  2673. The potential benefits ofย Rapamycinย on renal function, tolerance, fibrosis, and malignancy following transplantation
  2674. Target ofย Rapamycinย signaling in leukemia and lymphoma
  2675. Rapamycinย inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation
  2676. Targetedย inhibitionย of mammalian target ofย Rapamycinย for the treatment of advanced renal cell carcinoma
  2677. Target ofย Rapamycinย (TOR) mediates the transduction of nutritional signals into juvenile hormone production
  2678. Rapamycinย activates autophagy and improves myelination in explant cultures from neuropathic mice
  2679. Phase II trial of the oral mammalian target ofย Rapamycinย inhibitor everolimus in relapsed or refractory Waldenstrรถm macroglobulinemia
  2680. Mammalian target ofย Rapamycinย (mTOR) regulates cellular proliferation and tumor growth in urothelial carcinoma
  2681. The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target ofย Rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple โ€ฆ
  2682. Mammalian target ofย Rapamycin: biological function and target for novel anticancer agents
  2683. Mammalian target ofย Rapamycinย signaling activation patterns in neuroendocrine tumors of the lung
  2684. inhibitionย of mammalian target ofย Rapamycinย as a therapeutic strategy in the management of bladder cancer
  2685. Randomised trial of threeย Rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis: 2-year follow-up results
  2686. inhibitionย of mammalian target ofย Rapamycinย is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells
  2687. Perifosine inhibits mammalian target ofย Rapamycinย signaling through facilitating degradation of major components in theย mTORย axis and induces autophagy
  2688. The effect ofย Rapamycinย on bone growth in rabbits
  2689. Rapamycinย pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs
  2690. Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy withย Rapamycinย or cyclophosphamide
  2691. Rapamycinย induces transactivation of the EGFR and increases cell survival
  2692. Mammalian target ofย Rapamycinย inhibitorsย Rapamycinย and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro
  2693. Adiponectin modulates C-jun N-terminal kinase and mammalian target ofย Rapamycinย and inhibits hepatocellular carcinoma
  2694. B55ฮฒ-associated PP2A complex controls PDK1-directed myc signaling and modulatesย Rapamycinย sensitivity in colorectal cancer
  2695. High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules forย Rapamycinย by an emulsion-evaporation approach
  2696. Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target ofย Rapamycinย inhibition
  2697. Chemical genetics screen for enhancers ofย Rapamycinย identifies a specific inhibitor of an SCF family E3 ubiquitin ligase
  2698. Immune regulation byย Rapamycin: moving beyond T cells
  2699. First report on a series of HIV patients undergoingย Rapamycinย monotherapy after liver transplantation
  2700. โ€ฆ leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target ofย Rapamycinย signaling in rats
  2701. Rapamycinย reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model
  2702. Rapamycinย inhibits in vitro growth and release of angiogenetic factors in human bladder cancer
  2703. Mammalian target ofย Rapamycinย signaling modulates photic entrainment of the suprachiasmatic circadian clock
  2704. The tuberous sclerosis proteins regulate formation of the primary cilium via aย Rapamycin-insensitive and polycystin 1-independent pathway
  2705. Phospho-mTORย and phospho-4EBP1 in endometrial adenocarcinoma: association with stage and grade in vivo and link with response toย Rapamycinย treatment in vitro
  2706. Different effects of FK506,ย Rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets
  2707. Downregulation of Akt/mammalian target ofย Rapamycinย pathway in skeletal muscle is associated with increased REDD1 expression in response to chronic hypoxia
  2708. Dual targeting of AKT and mammalian target ofย Rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor
  2709. Mammalian target ofย Rapamycinย in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation
  2710. Effect ofย Rapamycin, anย mTORย inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status
  2711. Leptin modulates the survival of autoreactive CD4+ T cells through the nutrient/energy-sensing mammalian target ofย Rapamycinย signaling pathway
  2712. โ€ฆ skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target ofย Rapamycinย complex 1 signaling
  2713. Signaling events downstream of mammalian target ofย Rapamycinย complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor โ€ฆ
  2714. A phase I study of the mammalian target ofย Rapamycinย inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia
  2715. Morpholine derivatives greatly enhance the selectivity of mammalian target ofย Rapamycinย (mTOR) inhibitors
  2716. Intravesical delivery ofย Rapamycinย suppresses tumorigenesis in a mouse model of progressive bladder cancer
  2717. Complex regulation of mammalian target ofย Rapamycinย complex 1 in the basomedial hypothalamus by leptin and nutritional status
  2718. Mammalian target ofย Rapamycinย regulates vascular endothelial growth factorโ€“dependent liver cyst growth in polycystinโ€2โ€“defective mice
  2719. Rapamycinย sensitizes T-ALL cells to dexamethasone-induced apoptosis
  2720. Generation of high-yieldย Rapamycin-producing strains through protoplasts-related techniques
  2721. An expeditious route to fluorinatedย Rapamycinย analogues by utilising mutasynthesis
  2722. Mechanisms involved in the enhancement of mammalian target ofย Rapamycinย signalling and hypertrophy in skeletal muscle of myostatin-deficient mice
  2723. Mammalian target ofย Rapamycinย and diabetes: what does the current evidence tell us?
  2724. Mammalian target ofย Rapamycinย inhibitionย and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients
  2725. Treatment of refractory oral erosive lichen planus with topicalย Rapamycin: 7 cases
  2726. Cryptotanshinone inhibits cancer cell proliferation by suppressing mammalian target ofย Rapamycinโ€“mediated cyclin D1 expression and Rb phosphorylation
  2727. Tubers and tumors:ย Rapamycinย therapy for benign and malignant tumors
  2728. The pre-clinical assessment ofย Rapamycin-eluting, durable polymer-free stent coating concepts
  2729. Rapamycinย weekly maintenance dosing and the potential efficacy of combination sorafenib plusย Rapamycinย but not atorvastatin or doxycycline in tuberous โ€ฆ
  2730. EGFR signaling through an Akt-SREBP-1โ€“dependent,ย Rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy
  2731. Rapamycinย promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents
  2732. Expansion of the target ofย Rapamycinย (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity
  2733. Longโ€term blood vessel removal with combined laser and topicalย Rapamycinย antiangiogenic therapy: Implications for effective port wine stain treatment
  2734. R1507, a fully human monoclonal antibody targeting IGFโ€1R, is effective alone and in combination withย Rapamycinย in inhibiting growth of osteosarcoma xenografts
  2735. EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target ofย Rapamycinย โ€ฆ
  2736. Rapamycinย prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model
  2737. Mammalian target ofย Rapamycinย signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in โ€ฆ
  2738. Rapamycinย regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1
  2739. Activated mammalian target ofย Rapamycinย is a potential therapeutic target in gastric cancer
  2740. Mutual regulation of hypoxia-inducible factor and mammalian target ofย Rapamycinย as a function of oxygen availability
  2741. Rapamycinย selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients
  2742. Rapamycinย inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver
  2743. inhibitionย of human T-cell proliferation by mammalian target ofย Rapamycinย (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5)
  2744. Mammalian target ofย Rapamycinย is activated in association with myometrial proliferation during pregnancy
  2745. Expression status and prognostic significance of mammalian target ofย Rapamycinย pathway members in urothelial carcinoma of urinary bladder after cystectomy
  2746. A phase 2 study of the oral mammalian target ofย Rapamycinย inhibitor, everolimus, in patients with recurrent endometrial carcinoma
  2747. Mammalian target ofย Rapamycinย (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes
  2748. Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy ofย Rapamycin
  2749. Rapamycinย for refractory acute graft-versus-host disease
  2750. Life span extension by resveratrol,ย Rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging
  2751. Nucleus accumbens core mammalian target ofย Rapamycinย signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats
  2752. New approach for local delivery ofย Rapamycinย by bioadhesive PLGA-carbopol nanoparticles
  2753. Activation of the mammalian target ofย Rapamycinย signalling pathway in prostate cancer and its association with patient clinicopathological characteristics
  2754. โ€ฆ triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating cโ€Jun Nโ€terminal kinase, Akt and mammalian target ofย Rapamycinย โ€ฆ
  2755. Rapamycinย induces autophagic flux in neurons
  2756. Development and characterization of liposomal formulations forย Rapamycinย delivery and investigation of their antiproliferative effect on MCF7 cells
  2757. A pilot trial of theย mTORย (mammalian target ofย Rapamycin) inhibitor RAD001 in patients with advanced B-CLL
  2758. Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target ofย Rapamycinย and epidermal growth factor โ€ฆ
  2759. Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target ofย Rapamycinย (mTOR): Optimization of the 1-substituent
  2760. A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion withย Rapamycin-eluting stents
  2761. The target ofย Rapamycinย complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway
  2762. Mammalian target ofย Rapamycinย signaling and autophagy: roles in lymphangioleiomyomatosis therapy
  2763. Rapamycinย (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors
  2764. Targeted therapy of human osteosarcoma with 17AAG orย Rapamycin: characterization of induced apoptosis andย inhibitionย ofย mTORย and Akt/MAPK/Wnt pathways
  2765. Conversion toย Rapamycinย immunosuppression for malignancy after kidney transplantation
  2766. cAMP-dependent activation of mammalian target ofย Rapamycinย (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4
  2767. Immunosuppression using the mammalian target ofย Rapamycinย (mTOR) inhibitor everolimus: pilot study shows significant cognitive and affective improvement
  2768. Late progression of renal pathology and cyst enlargement is reduced byย Rapamycinย in a mouse model of nephronophthisis
  2769. Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target ofย Rapamycinย inhibitors
  2770. Oralย Rapamycinย reduces tumour burden and vascularization in Lkb1+/โˆ’ mice
  2771. Rapamycinย and MPA, but not CsA, impair human NK cell cytotoxicity due to differential effects on NK cell phenotype
  2772. NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor, elicits multifaceted antitumor activities in human gliomas
  2773. Broadening the therapeutic scope forย Rapamycinย treatment
  2774. Dual phosphoinositide 3-kinase/mammalian target ofย Rapamycinย blockade is an effective radiosensitizing strategy for the treatment of nonโ€“small cell lung cancer โ€ฆ
  2775. Upregulation of the mammalian target ofย Rapamycinย complex 1 pathway by Ras homolog enriched in brain in pancreatic ฮฒ-cells leads to increased ฮฒ-cell mass and โ€ฆ
  2776. mTORC1ย inhibitionย viaย Rapamycinย promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes
  2777. Mammalian target ofย Rapamycinย activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis
  2778. Effects of metformin on mammalian target ofย Rapamycinย in a mouse model of endometrial hyperplasia
  2779. Rapamycinย inhibits oncogenic intestinal ion channels and neoplasia in APC Min/+ mice
  2780. Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited byย Rapamycin
  2781. Early and late effects of the immunosuppressantsย Rapamycinย and mycophenolate mofetil on UV carcinogenesis
  2782. Curcumin inhibits carcinogen and nicotine-induced Mammalian target ofย Rapamycinย pathway activation in head and neck squamous cell carcinoma
  2783. Differing effects of systemically administeredย Rapamycinย on consolidation and reconsolidation of context vs. cued fear memories
  2784. The antidepressant sertraline inhibits translation initiation by curtailing mammalian target ofย Rapamycinย signaling
  2785. Vascular endothelial growth factor-C protects prostate cancer cells from oxidative stress by the activation of mammalian target ofย Rapamycinย complex-2 and AKT-1
  2786. Rapamycin-induced Gln3 dephosphorylation is insufficient for nuclear localization: Sit4 and PP2A phosphatases are regulated and function differently
  2787. Melatonin attenuates methamphetamineโ€induced deactivation of the mammalian target ofย Rapamycinย signaling to induce autophagy in SKโ€Nโ€SH cells
  2788. Monotherapyย Rapamycinย allows an increase of CD4+โ€ƒCD25bright+โ€ƒFoxP3+ T cells in renal recipients
  2789. Rapamycin: the cure for all that ails
  2790. Activation of mammalian target ofย Rapamycinย signaling in spatial learning
  2791. Dualย inhibitionย of mitogen-activated protein kinase kinase and mammalian target ofย Rapamycinย in differentiated and anaplastic thyroid cancer
  2792. Comparison of radiosensitizing effects of the mammalian target ofย Rapamycinย inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell โ€ฆ
  2793. The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย signaling network in normal myelopoiesis and leukemogenesis
  2794. MYC activity mitigates response toย Rapamycinย in prostate cancer through eukaryotic initiation factor 4Eโ€“binding protein 1โ€“mediatedย inhibitionย of autophagy
  2795. Successful control of intractable hypoglycemia usingย Rapamycinย in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases
  2796. Generation of highย Rapamycinย producing strain via rational metabolic pathwayโ€based mutagenesis and further titer improvement with fedโ€batch bioprocess โ€ฆ
  2797. Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia
  2798. Rapamycin-Insensitive Up-Regulation of MMP2 and Other Genes in Tuberous Sclerosis Complex 2โ€“Deficient Lymphangioleiomyomatosis-Like Cells
  2799. Increasing longevity through caloric restriction orย Rapamycinย feeding in mammals: common mechanisms for common outcomes?
  2800. Rapamycinย inhibits anal carcinogenesis in two preclinical animal models
  2801. Overexpression of the mammalian target ofย Rapamycin: a novel biomarker for poor survival in resected early stage non-small cell lung cancer
  2802. Mammalian target ofย Rapamycinย complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple proteinโ€“protein interactions โ€ฆ
  2803. Downregulation of Notch pathway by a ฮณ-secretase inhibitor attenuates AKT/mammalian target ofย Rapamycinย signaling and glucose uptake in an ERBB2 transgenic โ€ฆ
  2804. A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target ofย Rapamycinย signaling is sufficient to induce skeletal muscle hypertrophy
  2805. โ€ฆ -1, 3, 5-triazine) derivatives: potent adenosine 5โ€ฒ-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target ofย Rapamycinย inhibitors: discovery of โ€ฆ
  2806. Rapamycinย enhances LPS induction of tissue factor and tumor necrosis factor-ฮฑ expression in macrophages by reducing IL-10 expression
  2807. Rapamycinย protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivo
  2808. Pneumonitis associated with mammalian target ofย Rapamycinย inhibitors in renal transplant recipients: a single-center experience
  2809. Discovery of potent and selective inhibitors of the mammalian target ofย Rapamycinย (mTOR) kinase
  2810. Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor NVP-BEZ235
  2811. Rapamycinย inhibits IGF-1 stimulated cell motility through PP2A pathway
  2812. Mammalian target ofย Rapamycinย is a biomarker of poor survival in metastatic serous ovarian carcinoma
  2813. Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target ofย Rapamycin/S6 kinase 2 pathway
  2814. Treatment withย Rapamycinย ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces โ€ฆ
  2815. Rapamycinย and CCIโ€779 inhibit the mammalian target ofย Rapamycinย signalling in hepatocellular carcinoma
  2816. mTORย Ser-2481 autophosphorylation monitorsย mTORC-specific catalytic activity and clarifiesย Rapamycinย mechanism of action
  2817. Preclinical in vivo evaluation ofย Rapamycinย in human malignant peripheral nerve sheath explant xenograft
  2818. Hypersensitivity of Ph-positive lymphoid cell lines toย Rapamycin: Possible clinical application ofย mTORย inhibitor
  2819. Mammalian target ofย Rapamycinย complex 1 is involved in differentiation of regenerating myofibers in vivo
  2820. Rapamycinย as a therapy of choice after renal transplantation in a patient with tuberous sclerosis complex
  2821. Treating triple-negative breast cancer by a combination ofย Rapamycinย and cyclophosphamide: an in vivo bioluminescence imaging study
  2822. Antitumoral activity ofย Rapamycinย mediated throughย inhibitionย of HIF-1alpha and VEGF in hepatocellular carcinoma
  2823. Aberrant hyperactivation of akt and Mammalian target ofย Rapamycinย complex 1 signaling in sporadic chordomas
  2824. HIV-associated nephropathy: role of mammalian target ofย Rapamycinย pathway
  2825. Theย Rapamycin-regulated gene expression signature determines prognosis for breast cancer
  2826. โ€ฆ acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2ฮ”) mutants is influenced by the carbon source andย Rapamycin
  2827. Combined Bcl-2/Mammalian Target ofย Rapamycinย inhibitionย Leads to Enhanced Radiosensitization via Induction of Apoptosis and Autophagy in Nonโ€“Small Cell Lung โ€ฆ
  2828. Rapamycinย down-regulates inducible nitric oxide synthase by inducing proteasomal degradation
  2829. Functional interaction of mammalian target ofย Rapamycinย complexes in regulating mammalian cell size and cell cycle
  2830. Efficacy, tolerance, and safety of mammalian target ofย Rapamycinย inhibitors as rescue immunosuppressants in liver transplantation
  2831. Rapamycinย induces the TGFฮฒ1/Smad signaling cascade in renal mesangial cells upstream ofย mTOR
  2832. โ€ฆ 3-kinase (PI3K) and the mammalian target ofย Rapamycinย (mTOR): design, synthesis, and superior antitumor activity of novel wortmanninโˆ’ย Rapamycinย conjugates
  2833. Developing antiepileptogenic drugs for acquired epilepsy: targeting the mammalian target ofย Rapamycinย (mTOR) pathway
  2834. Hepatitis C virus NS5A activates the mammalian target ofย Rapamycinย (mTOR) pathway, contributing to cell survival by disrupting the interaction between โ€ฆ
  2835. Naive CD4 t cell proliferation is controlled by mammalian target ofย Rapamycinย regulation of GRAIL expression
  2836. Activation of the mammalian target ofย Rapamycinย signalling pathway in epidermal tumours and its correlation with cyclinโ€dependent kinase 2
  2837. The effects ofย Rapamycinย on lens epithelial cell proliferation, migration, and matrix formation: an in vitro study
  2838. Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression andย Rapamycinย treatment in Saccharomyces cerevisiae
  2839. Rapamycinย induces growth retardation by disrupting angiogenesis in the growth plate
  2840. โ€ฆ protects mouse and human hematopoietic progenitors from ฮณ-irradiation through extracellular signal-regulated kinase/mammalian target ofย Rapamycinย โ€ฆ
  2841. Rapamycinย inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment
  2842. Dramatic improvement in pulmonary hypertension withย Rapamycin
  2843. High expression of mammalian target ofย Rapamycinย is associated with better outcome for patients with early stage lung adenocarcinoma
  2844. Phase Ib study of weekly mammalian target ofย Rapamycinย inhibitor ridaforolimus (AP23573; MK-8669) with weekly paclitaxel
  2845. Expression of EBV latent antigens, mammalian target ofย Rapamycin, and tumor suppression genes in EBV-positive smooth muscle tumors: clinical and therapeutic โ€ฆ
  2846. Identification of functional FKB protein in Echinococcus granulosus: its involvement in the protoscolicidal action ofย Rapamycinย derivates and in calcium homeostasis
  2847. The role of phosphoinositide 3โ€kinase and phosphatidic acid in the regulation of mammalian target ofย Rapamycinย following eccentric contractions
  2848. Placental mammalian target ofย Rapamycinย and related signaling pathways in an ovine model of intrauterine growth restriction
  2849. Rapamycinย inhibits proliferation and migration of hepatoma cells in vitro
  2850. TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confersย Rapamycinย sensitivity
  2851. Rapamycinย response in tumorigenic and non-tumorigenic hepatic cell lines
  2852. Activation of the AKT and mammalian target ofย Rapamycinย pathways and the inhibitory effects ofย Rapamycinย on those pathways in canine malignant melanoma cell lines
  2853. Rapamycinย as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex: Case report
  2854. Rapamycin-eluting stents in the arterial duct: experimental observations in the pig model.
  2855. Device-based local delivery of siRNA against mammalian target ofย Rapamycinย (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation
  2856. mTORย inhibitorย Rapamycinย alone or combined with cisplatin inhibits growth of esophageal squamous cell carcinoma in nude mice
  2857. Exploring mammalian target ofย Rapamycinย (mTOR)ย inhibitionย for treatment of mantle cell lymphoma and other hematologic malignancies
  2858. Target ofย Rapamycinย (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei
  2859. Rapid modification of proteins using aย Rapamycin-inducible tobacco etch virus protease system
  2860. Concurrent and sequential administration of chemotherapy and the Mammalian target ofย Rapamycinย inhibitor temsirolimus in human cancer cells and xenografts
  2861. Mammalian target ofย Rapamycinย complex 1 (mTORC1) signaling in energy balance and obesity
  2862. Bortezomib can suppress activation ofย Rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates
  2863. Rapamycinย Prevents and Breaks the Anti-CD3โ€“Induced Tolerance in NOD Mice
  2864. Rapamycinย generates anti-apoptotic human Th1/Tc1 cells via autophagy for induction of xenogeneic GVHD
  2865. Polylactide-glycoli acid andย Rapamycinย coating intraocular lens prevent posterior capsular opacification in rabbit eyes
  2866. Regulation of cell death and epileptogenesis by the mammalian target ofย Rapamycinย (mTOR): a double-edged sword?
  2867. Rapamycinย inhibits growth of cholangiocarcinoma cells.
  2868. The Insulin-like Growth Factor-1 Receptorโ€“Targeting Antibody, CP-751,871, Suppresses Tumor-Derived VEGF and Synergizes withย Rapamycinย in Models of โ€ฆ
  2869. Rapamycinย induces autophagy in islets: relevance in islet transplantation
  2870. Mammalian target ofย Rapamycinย inhibitionย abrogates insulin-mediated mammary tumor progression in type 2 diabetes
  2871. Long-term clinical results following stenting of the left main stem: insights from RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) โ€ฆ
  2872. Rapamycinย by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells
  2873. Evaluation of in vivo antineoplastic effects ofย Rapamycinย in patients with chemotherapy-refractory AML
  2874. Expression and mechanism of mammalian target ofย Rapamycinย in age-related renal cell senescence and organ aging
  2875. Rapid improvement of nephrogenic systemic fibrosis withย Rapamycinย therapy: possible role of phospho-70-ribosomal-S6 kinase
  2876. Inactivation of mammalian target ofย Rapamycinย increases STAT1 nuclear content and transcriptional activity in ฮฑ4-and protein phosphatase 2A-dependent โ€ฆ
  2877. Testing intravitreal toxicity ofย Rapamycinย in rabbit eyes
  2878. Antagonism of the mammalian target ofย Rapamycinย selectively mediates metabolic effects of epidermal growth factor receptorย inhibitionย and protects human malignant โ€ฆ
  2879. ATP-mediated protein kinase B Akt/mammalian target ofย Rapamycinย mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes โ€ฆ
  2880. Delayed re-endothelialization withย Rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3ฮฒ inhibitor
  2881. Regulation of gene expression in hepatic cells by the mammalian Target ofย Rapamycinย (mTOR)
  2882. inhibitionย of mammalian target ofย Rapamycinย signaling potentiates the effects of allโ€trans retinoic acid to induce growth arrest and differentiation of human acute โ€ฆ
  2883. Rapamycinย enhances chemotherapyโ€induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells
  2884. Pilot study:ย Rapamycinย in advanced hepatocellular carcinoma
  2885. Mammalian target ofย Rapamycinย as a novel target in the treatment of hepatocellular carcinoma.
  2886. Mammalian target ofย Rapamycin: a new target in prostate cancer
  2887. MAPK, phosphatidylinositol 3-kinase, and mammalian target ofย Rapamycinย pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic โ€ฆ
  2888. Rapamycinย delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage
  2889. Theย Rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Aktโ€“mTORโ€“p70S6K pathway in human medullary thyroid carcinoma cells
  2890. Rapamycinย and the transcription factor C/EBPฮฒ as a switch in osteoclast differentiation: implications for lytic bone diseases
  2891. Mammalian target ofย Rapamycinย (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma โ€ฆ
  2892. Rapamycinย inhibits lung metastasis of B16 melanoma cells through downโ€regulating alphav integrin expression and upโ€regulating apoptosis signaling
  2893. Mammalian target ofย Rapamycinย (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain โ€ฆ
  2894. PKI-179: an orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target ofย Rapamycinย (mTOR) inhibitor
  2895. Effect ofย Rapamycinย on lifespan in Drosophila
  2896. Luteinizing hormone stimulates mammalian target ofย Rapamycinย signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase โ€ฆ
  2897. The effect ofย Rapamycinย on angiogenesis in chick chorioalantoic membrane
  2898. Mammalian target ofย Rapamycinย pathway promotes tumor-induced angiogenesis in adenoid cystic carcinoma: its suppression by isoliquiritigenin through dual โ€ฆ
  2899. Regulation of gastric hormones by systemicย Rapamycin
  2900. Effect of combination treatment ofย Rapamycinย and isoflavones onย mTORย pathway in human glioblastoma (U87) cells
  2901. Distinct subsets of Sit4 holophosphatases are required forย inhibitionย of Saccharomyces cerevisiae growth byย Rapamycinย and zymocin
  2902. Activation of phosphatidylinositol 3-kinase/Akt-mammalian target ofย Rapamycinย signaling pathway in the hippocampus is essential for the acquisition of morphine โ€ฆ
  2903. Rapamycinย inhibits re-endothelialization after percutaneous coronary intervention by impeding the proliferation and migration of endothelial cells and โ€ฆ
  2904. Critical and diverse involvement of Akt/mammalian target ofย Rapamycinย signaling in human lung carcinomas
  2905. โ€ฆ yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target ofย Rapamycinย (mTOR) Inhibitor for โ€ฆ
  2906. Phosphoinositide 3-kinase (PI3K) and the nutrient sensingย mTORย (mammalian target ofย Rapamycin) pathways control T cell migration
  2907. Glycogen synthase kinase-3 and mammalian target ofย Rapamycinย pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets
  2908. Periadventitialย Rapamycin-eluting microbeads promote vein graft disease in long-term pig vein-into-artery interposition grafts
  2909. Inhibitory effect ofย Rapamycinย and dexamethasone on production of IL-17 and IFN-ฮณ in Vogtโ€“Koyanagiโ€“Harada patients
  2910. Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target ofย Rapamycinย complex 1 to enhance proliferation
  2911. Novel mechanism of reducing tumourigenesis: upregulation of the DNA repair enzyme OGG1 byย Rapamycin-mediated AMPK activation andย mTORย inhibition
  2912. Rapamycinโ€Conditioned Donor Dendritic Cells Differentiate CD4+CD25+Foxp3+ T Cells In Vitro with TGFโ€ฮฒ1 for Islet Transplantation
  2913. Mammalian Target ofย Rapamycinโ€“Dependent Acinar Cell Neoplasia after Inactivation of Apc and Pten in the Mouse Salivary Gland: Implications for Human Acinic Cell โ€ฆ
  2914. The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target ofย Rapamycin
  2915. Rescue immunosuppression with mammalian target ofย Rapamycinย inhibitor drugs in liver transplantation
  2916. In-vitro release ofย Rapamycinย from a thermosensitive polymer for theย inhibitionย of vascular smooth muscle cell proliferation
  2917. Influence of combined treatment of low doseย Rapamycinย and cyclosporin A on corneal allograft survival
  2918. Low-doseย Rapamycinย reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex
  2919. Rapamycinย attenuates the severity of murine adriamycin nephropathy
  2920. Rapamycinย and curcumin induce apoptosis in primary resting B chronic lymphocytic leukemia cells
  2921. Stage 2 combination testing ofย Rapamycinย with cytotoxic agents by the Pediatric Preclinical Testing Program
  2922. Targeting the mammalian target ofย Rapamycinย to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma
  2923. Human Protein Phosphatase PP6 Regulatory Subunits Provide Sit4-Dependent andย Rapamycinโ€“Sensitive Sap Function in Saccharomyces cerevisiae
  2924. โ€ฆ cell marker upregulation in normal cutaneous vessels following pulsedโ€dye laser exposure and its abrogation by concurrentย Rapamycinย administration: implications for โ€ฆ
  2925. Monitoring kidney and renal cyst volumes applying MR approaches on aย Rapamycinย treated mouse model of ADPKD
  2926. Rapamycinย promotes the expansion of CD4+ Foxp3+ regulatory T cells after liver transplantation
  2927. โ€ฆ cells treated with mammalian target ofย Rapamycinย inhibitors: rationale for combined treatment with extracellular signalโ€“regulated kinase inhibitors andย Rapamycin
  2928. Effective treatment of advanced colorectal cancer byย Rapamycinย and 5-FU/oxaliplatin monitored by TIMP-1
  2929. Anti-CD154 mAb andย Rapamycinย induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation
  2930. Rictor phosphorylation on the Thr-1135 site does not require mammalian target ofย Rapamycinย complex 2
  2931. Comparison of threeย Rapamycinย dosing schedules in A/J Tsc2+/-mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice โ€ฆ
  2932. Effect ofย Rapamycinย on cue-induced drug craving in abstinent heroin addicts
  2933. Adenosine 5โ€ฒ-monophosphate-activated protein kinase-mammalian target ofย Rapamycinย cross talk regulates brown adipocyte differentiation
  2934. Intracellular parasitism with Toxoplasma gondii stimulates mammalianโ€targetโ€ofโ€Rapamycinโ€dependent host cell growth despite impaired signalling to S6K1 and 4E โ€ฆ
  2935. Dualย inhibitionย of class IA phosphatidylinositol 3-kinase and mammalian target ofย Rapamycinย as a new therapeutic option for T-cell acute lymphoblastic leukemia
  2936. The synergic effects ofย Rapamycinย and extremely low frequency electromagnetic field on angiogenesis
  2937. Rapamycinย therapy for renal, brain, and skin lesions in a tuberous sclerosis patient
  2938. Rapamycinย effects onย mTORย signaling in benign, premalignant and malignant human breast epithelial cells
  2939. Combinedย inhibitionย of MEK and mammalian target ofย Rapamycinย abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their โ€ฆ
  2940. Structural basis for the association of the redox-sensitive target ofย Rapamycinย FATC domain with membrane-mimetic micelles
  2941. NVโ€128, a novel isoflavone derivative, induces caspaseโ€independent cell death through the Akt/mammalian target ofย Rapamycinย pathway
  2942. Activating transcription factor 4 and CCAAT/enhancer-binding protein-ฮฒ negatively regulate the mammalian target ofย Rapamycinย via Redd1 expression in response to โ€ฆ
  2943. Epidermal growth factor receptor and mammalian target ofย Rapamycinย as therapeutic targets in malignant glioma: current clinical status and perspectives
  2944. Chemopreventive efficacy ofย Rapamycinย on Peutzโ€“Jeghers syndrome in a mouse model
  2945. โ€ฆ Stents Results in Better Clinical Outcomes During 6-Year Follow-Up Than Bare-Metal Stents: An Analysis of the RESEARCH (Rapamycin-Eluting Stent Evaluated At โ€ฆ
  2946. โ€ฆ repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target ofย Rapamycinย โ€ฆ
  2947. โ€ฆ of the epidermal growth factor receptor/mammalian target ofย Rapamycinย pathway by epidermal growth factor receptor inhibitors andย Rapamycinย results in reduced cell โ€ฆ
  2948. inhibitionย of the mammalian target ofย Rapamycinย promotes cyclic AMP-induced differentiation of NG108-15 cells
  2949. Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinaseโ€“protein kinase Bโ€“mammalian target ofย Rapamycinย signaling
  2950. The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย signaling network in cancer stem cell biology
  2951. โ€ฆ -6-aryl-1H-pyrazolo[3,4-d]pyrimidines as Highly Potent and Selective ATP-Competitive Inhibitors of the Mammalian Target ofย Rapamycinย (mTOR): Optimization of the โ€ฆ
  2952. PI3K signaling regulatesย Rapamycin-insensitive translation initiation complex formation in vaccinia virus-infected cells
  2953. Silymarin inhibits endothelial progenitor cellsโ€™ senescence and protects against the antiproliferative activity ofย Rapamycin: preliminary study
  2954. inhibitionย of voltage-gated K+ channels in dendritic cells byย Rapamycin
  2955. Phase I study of the oral mammalian target ofย Rapamycinย inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma
  2956. Regulation by FK506 andย Rapamycinย of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins andย mTOR
  2957. โ€ฆ using bare-metal and drug-eluting stents in previously untreated coronary artery disease: insights from the RESEARCH (Rapamycin-Eluting Stent Evaluated at โ€ฆ
  2958. Rrd1 isomerizes RNA polymerase II in response toย Rapamycin
  2959. Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target ofย Rapamycinย activity and p27Kip1 โ€ฆ
  2960. Rapamycinย impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism
  2961. If mammalian target of metformin indirectly is mammalian target ofย Rapamycin, then the insulin-like growth factor-1 receptor axis will audit the efficacy of metformin in โ€ฆ
  2962. The transcription factor SP1 regulates centriole function and chromosomal stability through a functional interaction with the mammalian target ofย Rapamycin/raptor โ€ฆ
  2963. Involvement of autophagy via mammalian target ofย Rapamycinย (mTOR)ย inhibitionย in tributyltin-induced neuronal cell death
  2964. Rapamycinย protects heart from ischemia/reperfusion injury independent of autophagy by activating PI3 kinase-Akt pathway and mitochondria KATP channel
  2965. โ€ฆ peroxisome proliferator-activated receptor (PPAR) ฮณ protein translation by suppressing the mammalian target ofย Rapamycinย (mTOR) signaling pathway in โ€ฆ
  2966. SP600125 negatively regulates the mammalian target ofย Rapamycinย via ATF4-induced Redd1 expression
  2967. โ€ฆ in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target ofย Rapamycin
  2968. Rapamycinย Inhibits VEGFโ€Induced Microvascular Hyperpermeability In Vivo
  2969. Iron deficiency down-regulates the Akt/TSC1-TSC2/mammalian Target ofย Rapamycinย signaling pathway in rats and in COS-1 cells
  2970. Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target ofย Rapamycinย pathway identifies deformed epidermal autoregulatory factor-1 as a โ€ฆ
  2971. Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation byย Rapamycinย in human myeloma cells
  2972. Rapamycinย for focal segmental glomerulosclerosis: a report of 3 cases
  2973. inhibitionย of mammalian target ofย Rapamycinย (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E โ€ฆ
  2974. Regression of left ventricular hypertrophy in kidney transplant recipients: the potential role forย inhibitionย of mammalian target ofย Rapamycin
  2975. โ€ฆ by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein ofย Rapamycinย โ€ฆ
  2976. Rapamycinย inhibits cholangiocyte regeneration by blocking interleukinโ€6โ€“induced activation of signal transducer and activator of transcription 3 after liver โ€ฆ
  2977. A role for mammalian target ofย Rapamycinโ€“mTOR-pathway in non alcoholic steatohepatitis related-cirrhosis
  2978. Targeting mammalian target ofย Rapamycinย to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines
  2979. Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin withย Rapamycinย plus tacrolimus in liver transplant patient
  2980. Rapamycinย promotes the enrichment of CD4+ CD25hiFoxP3+ T regulatory cells from naive CD4+ T cells of baboon that suppress antiporcine xenogenic response in โ€ฆ
  2981. Rapamycin, but not cyclosporine A, inhibits vascularization and incorporation of implanted surgical meshes
  2982. Rapamycinโ€treated mature dendritic cells have a unique cytokine secretion profile and impaired allostimulatory capacity
  2983. Rapamycinย induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes
  2984. Effectiveย inhibitionย of xenografts of hepatocellular carcinoma (HepG2) byย Rapamycinย and bevacizumab in an intrahepatic model
  2985. Inducible somatic oocyte destruction in response toย Rapamycinย requires wild-type regulation of follicle cell epithelial polarity
  2986. Cutaneous Tโ€cell lymphoma cells are sensitive toย Rapamycin
  2987. โ€ฆ ligand mediates follicular lymphoma B-cell proliferation and cyclin D1 expression through phosphatidylinositol 3-kinaseโ€“regulated mammalian target ofย Rapamycinย โ€ฆ
  2988. Mammalian target ofย Rapamycinย (mTOR) and S6 kinase down-regulate phospholipase D2 basal expression and function
  2989. Rapamycinย enhances the susceptibility of both androgen-dependent and-independent prostate carcinoma cells to docetaxel
  2990. The phosphatidylinositol 3-kinase-AKT-mammalian target ofย Rapamycinย signaling network and the control of normal myelopoiesis
  2991. CD4+ Foxp3+ regulatory T cells converted byย Rapamycinย from peripheral CD4+ CD25หœ. naive T cells display more potent regulatory abilityin vitro
  2992. Chemistry and pharmacology ofย Rapamycinย and its derivatives
  2993. Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target ofย Rapamycinย (mTOR) inhibitor RAD001 strongly inhibits adhesion and โ€ฆ
  2994. Mammalian target of theย Rapamycinย pathway is involved in non-alcoholic fatty liver disease
  2995. Antiproliferative effects ofย Rapamycinย and celecoxib in angiosarcoma cell lines
  2996. Phase 1 and pharmacokinetic study of everolimus, a mammalian target ofย Rapamycinย inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung โ€ฆ
  2997. mTORย inhibitorย Rapamycinย suppresses striatal post-ischemic LTP
  2998. Ribosomal protein S6 kinase is a critical downstream effector of the target ofย Rapamycinย complex 1 for long-term facilitation in Aplysia
  2999. FK506 andย Rapamycinย neuroprotect erection and involve different immunophilins in a rat model of cavernous nerve injury
  3000. Rapamycinย increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translationalย inhibitionย of mdm2 in cancer cells
  3001. MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, andย Rapamycinย โ€ฆ
  3002. Lysosomal accumulation ofย mTORย is enhanced byย Rapamycin
  3003. Systemicย Rapamycinย without loading dose for restenosis prevention after coronary bare metal stent implantation
  3004. Beclin 1 selfโ€association is independent of autophagy induction by amino acid deprivation andย Rapamycinย treatment
  3005. High expression levels of the mammalian target ofย Rapamycinย inhibitor DEPTOR are predictive of response to thalidomide in myeloma
  3006. โ€ฆ of the effects of NF-ฮบB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264. 7 cells: synergistic effects ofย Rapamycinย on LPS-induced โ€ฆ
  3007. Combined administration of a mutant TGF-ฮฒ1/Fc andย Rapamycinย promotes induction of regulatory T cells and islet allograft tolerance
  3008. Evidence for cell cycle-dependent,ย Rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244
  3009. Rapamycinย reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells
  3010. Effect of low-doseย Rapamycinย on tumor growth in two human hepatocellular cancer cell lines
  3011. The serine 2481-autophosphorylated form of mammalian Target Ofย Rapamycinย (mTOR) is localized to midzone and midbody in dividing cancer cells
  3012. Rapamycin: could it enhance vaccine efficacy?
  3013. Rapamycinย and tacrolimus differentially modulate acute graftโ€versusโ€host disease in rats after liver transplantation
  3014. Infarct size is increased in female post-MI rats treated withย Rapamycin
  3015. Protein kinase C-ฮด and phosphatidylinositol 3-kinase/Akt activate mammalian target ofย Rapamycinย to modulate NF-ฮบB activation and intercellular adhesion โ€ฆ
  3016. Glutamate-dependent phosphorylation of the mammalian target ofย Rapamycinย (mTOR) in Bergmann glial cells
  3017. Rapid regression of lymphadenopathy uponย Rapamycinย treatment in a child with autoimmune lymphoproliferative syndrome
  3018. Lead optimization of N-3-substituted 7-morpholinotriazolopyrimidines as dual phosphoinositide 3-kinase/mammalian target ofย Rapamycinย inhibitors: discovery of PKI โ€ฆ
  3019. mTOR, the mammalian target ofย Rapamycin
  3020. Oralย Rapamycinย attenuates atherosclerosis without affecting the arterial responsiveness of resistance vessels in apolipoprotein E-deficient mice
  3021. Glucagon acts in a dominant manner to repress insulin-induced mammalian target ofย Rapamycinย complex 1 signaling in perfused rat liver
  3022. Targeting heatโ€shock protein 90 improves efficacy ofย Rapamycinย in a model of hepatocellular carcinoma in mice
  3023. Rapamycin, theย mTORย kinase inhibitor, sensitizes acute myeloid leukemia cells, HL-60 cells, to the cytotoxic effect of arabinozide cytarabine
  3024. inhibitionย of human immunodeficiency virus (HIVโ€1) infection in human peripheral blood leucocytesโ€SCID reconstituted mice byย Rapamycin
  3025. Mammalian target ofย Rapamycinย activity is required for expansion of CD34+ hematopoietic progenitor cells
  3026. Effects ofย Rapamycinย on prostate cancer PC-3 cells
  3027. Fiveโ€year clinical outcomes after coronary stenting of chronic total occlusion using sirolimusโ€eluting stents: Insights from theย Rapamycinโ€eluting stent evaluated at โ€ฆ
  3028. โ€ฆ of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but notย Rapamycin
  3029. Failed rescue therapy withย Rapamycinย after paraquat intoxication
  3030. mTORย pathway inhibitors in cancer therapy: moving pastย Rapamycin
  3031. A spectrophotometric assay for routine measurement of mammalian target ofย Rapamycinย activity in cell lysates
  3032. Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin andย Rapamycinย in a renal transplant recipient
  3033. Rapamycinย in combination with donor-specific CD4+ CD25+ Treg cells amplified in vitro might be realize the immune tolerance in clinical organ transplantation
  3034. Shiga toxin 1-induced proinflammatory cytokine production is regulated by the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย signaling pathway
  3035. Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target ofย Rapamycinย (mTOR) with selectivity over PI3Kฮฑ
  3036. Timing of conversion to mammalian target ofย Rapamycinย inhibitors is crucial in liver transplant recipients with impaired renal function at transplantation
  3037. Novel benzofuran-3-one indole inhibitors of PI3 kinase-ฮฑ and the mammalian target ofย Rapamycin: Hit to lead studies
  3038. Fission yeast TOR andย Rapamycin
  3039. Activated mammalian target ofย Rapamycinย is associated with T regulatory cell insufficiency in nasal polyps
  3040. Rapamycinย or tacrolimus alone fails to resist cardiac allograft accelerated rejection mediated by alloreactive CD4+ memory T cells in mice
  3041. A functional link between polo-like kinase 1 and the mammalian target-of-Rapamycinย pathway?
  3042. The combination of multiple receptor tyrosine kinase inhibitor and mammalian target ofย Rapamycinย inhibitor overcomes erlotinib resistance in lung cancer cell lines โ€ฆ
  3043. Experience with everolimus (RAD001), an oral mammalian target ofย Rapamycinย inhibitor, in patients with systemic mastocytosis
  3044. Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor
  3045. Rapamycinย impairs trabecular bone acquisition from highโ€dose but not lowโ€dose intermittent parathyroid hormone treatment
  3046. Steady-state kinetic andย inhibitionย studies of the mammalian target ofย Rapamycinย (mTOR) kinase domain andย mTORย complexes
  3047. Rapamycinย inhibits hepatectomy-induced stimulation of metastatic tumor growth by reduction of angiogenesis, microvascular blood perfusion, and tumor cell โ€ฆ
  3048. Impact of mammalian target ofย Rapamycinย inhibitionย on autosomal-dominant polycystic kidney disease
  3049. Limited utility ofย Rapamycinย in severe, refractory Wegenerโ€™s granulomatosis
  3050. Rescuing 3T3-L1 adipocytes from insulin resistance induced by stimulation of Akt-mammalian target ofย Rapamycin/p70 S6 kinase (S6K1) pathway and serine โ€ฆ
  3051. MYC activity mitigates response toย Rapamycinย in prostate cancer through 4EBP1-mediatedย inhibitionย of autophagy
  3052. Target ofย Rapamycinย in the oriental fruit fly Bactrocera dorsalis (hendel): its cloning and effect on yolk protein expression
  3053. Rapamycinย enhances aplaviroc anti-HIV activity: implications for the clinical development of novel CCR5 antagonists
  3054. Reducing the risk of left ventricular hypertrophy in kidney transplant recipients: the potential role of mammalian target ofย Rapamycin
  3055. Molecular pathways involved in hair follicle tumor formation: all about mammalian target ofย Rapamycin?
  3056. Posttransplantation Therapeuticย Rapamycinย Concentration Protects Nitric Oxideโ€“Related Vascular Endothelial Function: Comparative Effects in Rat Thoracic Aorta โ€ฆ
  3057. Controversies in breast cancer: the mammalian target ofย Rapamycinย as a target for breast cancer therapy
  3058. WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target ofย Rapamycinย inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed โ€ฆ
  3059. AZD6244 (ARRYโ€142886) enhances the antitumor activity ofย Rapamycinย in mouse models of human hepatocellular carcinoma
  3060. Increased frequency of regulatory T cells and selection of highly potent CD62L+ cells during treatment of human lung transplant recipients withย Rapamycin
  3061. Comparison ofย Rapamycin-and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction
  3062. Regulation of protein kinase Cฮด downregulation by protein kinase Cฮต and mammalian target ofย Rapamycinย complex 2
  3063. Rapamycinย reduces proteinuria and renal damage in the rat remnant kidney model
  3064. How does the mammalian target ofย Rapamycinย (mTOR) influence CD8 T-cell differentiation?
  3065. Alteration of REDD1-mediated mammalian target ofย Rapamycinย pathway and hypoxia-inducible factor-1ฮฑ regulation in human breast cancer
  3066. Immunohistochemical analysis of the mammalian target ofย Rapamycinย signalling pathway in extramammary Pagetโ€™s disease
  3067. Preventing restenosis after implantation of bare stents with oralย Rapamycin: a randomized angiographic and intravascular ultrasound study with a 5-year clinical follow โ€ฆ
  3068. Rapamycinย can Inhibit the Development of Chlamydia pneumoniae, which Might Partly Contribute to the Prevention of In-stent Restenosis
  3069. Depletion of mammalian target ofย Rapamycinย (mTOR) via siRNA mediated knockdown leads to stabilization of ฮฒ-catenin and elicits distinct features of โ€ฆ
  3070. Indirect antitumor effects of mammalian target ofย Rapamycinย inhibitors against Kaposi sarcoma in transplant patients
  3071. โ€ฆ -pyrrolo [2, 3-b] pyridin-3-yl) methylene-4-hydroxybenzofuran-3 (2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target ofย Rapamycinย โ€ฆ
  3072. Inhibitors of the mammalian target ofย Rapamycinย and transplant tolerance
  3073. Clinical implications of proteinuria in renal transplant recipients switching toย Rapamycinย for chronic allograft dysfunction
  3074. Transforming growth factor beta 1 (TGF-ฮฒ1) andย Rapamycinย synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs
  3075. Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinalย Rapamycin-sensitive pathways in the rat
  3076. โ€ฆ replacement in 6-aryl-1H-pyrazolo [3, 4-d] pyrimidines and 2-arylthieno [3, 2-d] pyrimidines: ATP-competitive inhibitors of the mammalian target ofย Rapamycinย (mTOR)
  3077. Mycophenolate mofetil versusย Rapamycinย in Han: SPRD rats with polycystic kidney disease
  3078. Rapamycinย sensitizes Aktย inhibitionย in malignant human breast epithelial cells
  3079. Protection fromย Rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling
  3080. Suppression ofย mTORย complex 2โ€dependent AKT phosphorylation in melanoma cells by combined treatment withย Rapamycinย and LY294002
  3081. Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined withย Rapamycinย in human orthotopic primary pancreatic cancer xenografts
  3082. Effects of delayedย Rapamycinย treatment on renal fibrosis and inflammation in experimental ischemia reperfusion injury
  3083. Cutting edge: Expression of the transcription factor E74-like factor 4 is regulated by the mammalian target ofย Rapamycinย pathway in CD8+ T cells
  3084. Loss of inhibitory insulin receptor substrate-1 phosphorylation is an early event in mammalian target ofย Rapamycinโ€“dependent endometrial hyperplasia and carcinoma
  3085. Rapamycinย inhibits yeast nucleotide excision repair independently of Tor kinases
  3086. ID2โ€VEGFโ€related Pathways in the Pathogenesis of Kaposiโ€™s Sarcoma: A Link Disrupted byย Rapamycin
  3087. Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target ofย Rapamycinย โ€ฆ
  3088. Novel mechanism ofย Rapamycinย in GVHD: increase in interstitial regulatory T cells
  3089. Low-dose calcineurin inhibitor regimen combined with mammalian target ofย Rapamycinย inhibitors preserves kidney functions in renal transplant recipients without โ€ฆ
  3090. Rapamycinย for chemoprevention of upper aerodigestive tract cancers
  3091. Mutation of a phosphorylatable residue in Put3p affects the magnitude ofย Rapamycin-induced PUT1 activation in a Gat1p-dependent manner
  3092. Spreading of mesothelioma cells isย Rapamycinโ€sensitive and requires continuing translation
  3093. Rapamycinย enhances platelet aggregation induced by adenosine diphosphate in vitro
  3094. Insulin resistance without elevated mammalian target ofย Rapamycinย complex 1 activity in muscles of mice fed a high-fat diet
  3095. 4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target ofย Rapamycinย (mTOR)
  3096. Serine 2481-autophosphorylation of mammalian target ofย Rapamycinย (mTOR) couples with chromosome condensation and segregation during mitosis: Confocal โ€ฆ
  3097. Mammalian target ofย Rapamycinย inhibitionย prevents glomerular hypertrophy in a model of renal mass reduction
  3098. Select nutrients in the ovine uterine lumen. VI. Expression of FK506-binding protein 12-Rapamycinย complex-associated protein 1 (FRAP1) and regulators and effectors โ€ฆ
  3099. The effect ofย Rapamycinย liposome gutta inhibiting rat corneal neovascularization
  3100. Retracted: CCR5 blockade in combination withย Rapamycinย prolongs cardiac allograft survival in mice
  3101. Rapamycinย joins the aging fray: maybe Ponce de Leon visited Rapa Nui, not Florida
  3102. Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination withย Rapamycinย inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo
  3103. Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined withย Rapamycin
  3104. Rapamycinย does not adversely affect intrahepatic islet engraftment in mice and improves early islet engraftment in humans
  3105. Late conversion to mammalian target ofย Rapamycinย inhibitor/proliferation signal inhibitors in kidney transplant patients: clinical experience in the last 5 years
  3106. โ€ฆ between a prospective randomised multicentre cutting balloon angioplasty and bare metal stent trial (REDUCE III) and theย Rapamycin-Eluting Stent Evaluation At โ€ฆ
  3107. โ€ฆ growthย inhibitionย is augmented by synchronousย inhibitionย of the insulin-like growth factor-1 receptor by NVP-AEW541 andย inhibitionย of mammalian target ofย Rapamycinย โ€ฆ
  3108. Rapamycinย suppresses the expansion and differentiation of porcine neonatal pancreas cell clusters
  3109. The possible cellular mechanism for extending lifespan of mice withย Rapamycin
  3110. Rapamycinย reduces kidney volume and delays the loss of renal function in a patient with autosomal-dominant polycystic kidney disease
  3111. โ€ฆ posttranscriptional regulation of insulin-like growth factor-I receptor level via glycogen synthase kinase-3ฮฒ and mammalian target ofย Rapamycinย in adrenal chromaffin โ€ฆ
  3112. Preparation of electrospun poly (L-lactide-co-caprolactone-co-glycolide)/phospholipid polymer/Rapamycinย blended fibers for vascular application
  3113. Combined effect ofย Rapamycinย and cisplatin on survival of Hep-2 cells in vitro
  3114. Adenosine-triphosphate promoting repair of spinal cord injury by activating mammalian target ofย Rapamycin/signal transducers and activators of transcription 3 signal โ€ฆ
  3115. Mammalian target ofย Rapamycinย complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization
  3116. Rapamycinย for Kaposiโ€™s sarcoma and graft-versus-host disease in bone marrow transplant recipient
  3117. Rapamycinย instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma
  3118. First-in-man use of polymer-free valsartan-eluting stents in small coronary vessels: a comparison to polymer-freeย Rapamycinย (2%)-eluting stents
  3119. Mammalian target ofย Rapamycinย and autosomal dominant polycystic kidney disease
  3120. Rapamycin-induced proteinuria following allogeneic hematopoietic stem cell transplantation
  3121. Effect ofย Rapamycinย on leukemia cell lines
  3122. inhibitionย of IGF-I receptor signaling in combination withย Rapamycinย or temsirolimus increases MYC-N phosphorylation
  3123. Role of GLUT1 in the Mammalian Target ofย Rapamycinย Pathway: Mechanisms of Regulation.
  3124. Exendin-4 protects pancreatic beta cells from the cytotoxic effect ofย Rapamycinย by inhibiting JNK and p38 phosphorylation
  3125. inhibitionย of mammalian target ofย Rapamycinย (mTOR) in advanced pancreatic cancer: The results of two prospective phase II studies
  3126. Monitoring Molecular-Specific Pharmacodynamics ofย Rapamycinย In vivo with Inducible Gal4โ†’ Fluc Transgenic Reporter Mice
  3127. Combination of tipifarnib andย Rapamycinย synergistically inhibits the growth of leukemia cells and overcomes resistance to tipifarnib via alteration of cellular signaling โ€ฆ
  3128. Pretreatment with intraluminalย Rapamycinย nanoparticle perfusion inhibits neointimal hyperplasia in a rabbit vein graft model
  3129. Rapamycinย prevents Concanavalin Aโ€induced liver injury by inhibiting lymphocyte activation
  3130. Treatment algorithms in metastatic renal cell carcinoma, including the potential role of the novel oral mammalian target ofย Rapamycinย inhibitor Everolimus
  3131. Cyclooxygenase 2 mediates the antiangiogenic effect ofย Rapamycinย in Ewing sarcoma
  3132. Rapamycinย selectively reduces the association of transcripts containing complex 5โ€ฒ UTRs with ribosomes in C4โ€2B prostate cancer cells
  3133. Regioselective lipase-catalyzed acylation of 41-desmethoxy-Rapamycinย without vinyl esters
  3134. Rapamycinย inhibits poly (ADP-ribosyl) ation in intact cells
  3135. Early loss of mammalian target ofย Rapamycinย complex 1 (mTORC1) signalling and reduction in cell size during dominant-negative suppression of hepatic โ€ฆ
  3136. Combination Regimens of nab-Rapamycinย (ABI-009) Effective Against MDA-MB-231 Breast-Tumor Xenografts.
  3137. Rapamycinย Inhibits Activator Protein-1 But Not Nuclear Factor-ฮบB Activity of Mature Bone Marrow-Derived Dendritic Cells
  3138. Autosomal dominant polycystic kidney disease (ADPKD):ย Rapamycinย as a new treatment option
  3139. Synthesis of the northern sector (C8โ€“C19) ofย Rapamycinย via Chan rearrangement and oxidation of an ฮฑ-acyloxyacetate
  3140. Rapamycinย and thalidomide treatment of a patient with refractory metastatic gastroesophageal adenocarcinoma: a case report
  3141. Effects ofย Rapamycinย on Breast Cancer Cell Migration through the Cross-Talk of MAPK Pathway.
  3142. inhibitionย of mammalian target ofย Rapamycin: the janus face of immunosuppression?
  3143. Effect ofย Rapamycinย on proliferated human umbilical vein endothelial cell
  3144. โ€ฆ 5โ€(2โ€chloroethyl)โ€2โ€acetoxyโ€benzyl]โ€4โ€(2โ€chloroethyl)โ€phenyl acetate inhibits phosphoinositide 3โ€kinase/Akt/mammalian target ofย Rapamycinย signalling through JNK โ€ฆ
  3145. Progression of graft fibrosis under mammalian target ofย Rapamycinย inhibitorโ€based regimen
  3146. Effects ofย Rapamycinย on the differentiation and function of macrophages in vitro
  3147. Monotherapyย Rapamycinย in renal transplant recipients with lymphoma successfully treated with rituximab
  3148. Rapamycinย enhances lipopolysaccharide-induced apoptosis and lung injury
  3149. Rapamycinย treatment suppresses epileptogenic activity in conditional Pten knockout mice
  3150. Influence ofย Rapamycinย on autophagy and apoptosis of two lepidoptera cell lines.
  3151. Effect ofย Rapamycinย on proliferation of acute myeloid leukemia cell lines HL-60 and HL-60/VCR
  3152. A phase II trial of a mammalian target ofย Rapamycinย inhibitor, temsirolimus, in patients with metastatic breast cancer.
  3153. Molecular pathways in metastatic renal cell carcinoma: the evolving role of mammalian target ofย Rapamycinย inhibitors
  3154. Anti-insulin-like growth factor-1 receptor (IGF-IR) monoclonal antibody cixutumumab plus mammalian target ofย Rapamycinย (mTOR) inhibitor temsirolimus in metastatic โ€ฆ
  3155. Effect ofย Rapamycinย and Cyclosporin A on the expression of TLR5 and Foxp3 in allorejection
  3156. Combination therapy of 5-fluorouracil withย Rapamycinย for hormone receptor-negative human breast cancer
  3157. โ€ฆ of D-cyclin translationย inhibitionย in myeloma cells treated withย mTORย inhibitors: rationale for combined treatment with ERK inhibitors andย Rapamycin
  3158. Dualย inhibitionย of Akt/mTORย pathway by nab-Rapamycinย and perifosine induces anti-tumor activity in multiple myeloma
  3159. Forever young, slim and fit:ย Rapamycinย to the rescue
  3160. Evaluation of aย Rapamycinโ€regulated serotype 2 adenoโ€associated viral vector in macaque parotid glands
  3161. Recent developments ofย Rapamycinย analogues
  3162. Combination ofย Rapamycinย and IL-2 do not affect antigen presentation ability of rat B cell and could promote Tregs proliferation and inhibitory activity
  3163. Mammalian target ofย Rapamycin: MasTOR mediator of cellular changes in pathological states?
  3164. Use of a cocktail regimen consisting of soluble galectin-1,ย Rapamycinย and histone deacetylase inhibitor may effectively prevent type 1 diabetes
  3165. Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses toย Rapamycin
  3166. Mammalian target ofย Rapamycin, Akt, and phosphatidylinositol 3-kinase signaling
  3167. Prevention of hepatic tumor growth and metastasis in rats withย Rapamycin
  3168. Effect ofย Rapamycinย on apoptosis in human myelodysplastic syndrome cell line MUTZ-1 and its possible mechanisms
  3169. A phase I dose-finding and pharmacodynamic study ofย Rapamycinย in combination with bevacizumab in patients with unresectable hepatocellular carcinoma.
  3170. Antitumor activity, and antiangiogenic activity of nanoparticle albumin-bound nab-Rapamycinย in combination with nab-paclitaxel.
  3171. Mammalian target ofย Rapamycinย (mTOR)-induced pneumonitis: Single-institution experience and treatment.
  3172. inhibitionย of cell growth byย Rapamycinย through targeting mammalian target ofย Rapamycinย signaling pathway in nasopharyngeal carcinoma
  3173. Study advance ofย Rapamycinย in the field of transplantation immunology [J]
  3174. Release test ofย Rapamycinย in drug-eluting stents
  3175. The mechanism and influence ofย Rapamycinย on proliferation of NIH3T3 fibroblasts transfected withย mTORย gene [J]
  3176. Effects ofย Rapamycinย on angiogenesis and tumor progression in human hepatocellular carcinoma implantation mice
  3177. Correlation factors of vascular restenosis and safety followingย Rapamycinย drug-eluting stent implantation
  3178. Mammalian target ofย Rapamycin, its mode of action and clinical response in metastatic clear cell carcinoma
  3179. Regulation of bone formation usingย Rapamycin-induced BMP2 expression system: influence of implanted cell number
  3180. Active-site inhibitors ofย mTORย targetย Rapamycin-resistant outputs ofย mTORC1 andย mTORC2, PLoS Biol
  3181. Effect ofย Rapamycinย on proliferation, apoptosis and regulation of chemokine receptor CXCR4 in RPMI8226 cells
  3182. Abstract C62: Identification of GSK2126458, a highly potent inhibitor of phosphoinositide 3โ€kinase (PI3K) and the mammalian target ofย Rapamycinย (mTOR)
  3183. Rapamycinย and HIV Replication in Liver Transplant Recipients
  3184. Effects ofย Rapamycin-loaded poly (lactic-co-glycolic) acid nanoparticles on distribution of cell cycle, expression of p27 protein, and proliferation of human umbilical โ€ฆ
  3185. Rapamycinย induces apoptosis of lung adenocarcinoma cell A549 under hypoxia and its molecular mechanism
  3186. A phase I study of sirolimus (Rapamycin) and bevacizumab in patients with advanced malignancies.
  3187. Effects ofย Rapamycinย on collagen type โ…  expression in rat myocardial cell induced by CVB 3
  3188. Abstract C65: Enhanced antitumor effect by the combination of a PI3K inhibitor ZSTK474 with anย mTORย inhibitorย Rapamycin
  3189. A stimulating new role forย Rapamycin
  3190. Synergistic augmentation of cisplatin-induced apoptosis in HeLa cells byย Rapamycin
  3191. Evaluation for synergistic suppression of breast cancer proliferation by Chloroquine in combination with theย Rapamycinย derivative, Rad001
  3192. Rapamycinย enhances lifespan: At last, an advantage for transplant recipients?
  3193. Rapamycinย reverses glucocorticoid resistance in human T-cell acute lymphoblastic leukemia CEM-C1 cells [J]
  3194. Effects ofย Rapamycinย on nephropathy of diabetic rats and expressions of vascular endothelial growth factor and its receptor [J]
  3195. Interference ofย mTORย expression enhances sensitivity of esophageal squamous cell carcinoma EC9706 cells toย Rapamycin
  3196. Can phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitionย ERase them all?
  3197. Tuberous Sclerosis Complex and the Mammalian Target ofย Rapamycinย Pathways
  3198. Comparison of the MEIA and HPLC assays for the measurement ofย Rapamycinย concentration in blood of recipients after renal transplantation [J]
  3199. Effects of simvastatin onย Rapamycin-treated cardiac microvascular endothelial cells
  3200. Combinedย Rapamycinย eye drop in nanometer vector and poly (lactic acid) wafers of cyclosporine A effectively prevents high-risk corneal allograft rejection in rabbits
  3201. Mammalian target ofย Rapamycinย inhibitors in the treatment of malignancy after organ transplantation
  3202. Target ofย Rapamycinย modulators of and use thereof
  3203. Essential Role of Mammalian Target ofย Rapamycinย (mTOR) in LH-dependent Testosterone Production in Rat Leydig Cells.
  3204. Rapamycinย inhibits growth and metastasis of gallbladder cancer GBC-SD cells.
  3205. Pharmacological studies of a novel inhibitor of the mammalian target ofย Rapamycinย (mTOR) signaling pathway
  3206. Effects ofย Rapamycinย onย mTOR/p70S6K signaling pathway and tumor growth in xenografted esophageal squamous cell carcinoma.
  3207. Effect ofย Rapamycinย (serolimus) on in vitro cultured human keratinocytes
  3208. Mesenchymal stem cells combined withย Rapamycinย immuno-regulates the spleniclymphocytes in allogenic mice.
  3209. Effect ofย Rapamycinย on the interaction between Salmonella typhi plasmid pR_ (ST98) and macrophages [J]
  3210. Expression of JAK/STAT signal transduction pathway and the effects ofย Rapamycinย in lupus nephritis-prone MRL/lpr mice
  3211. CIRCULATING CD4CD25 HIGH CD127 LOW REGULATORY T-CELLS AFTER INTRACORONARY IMPLANTATION OFย Rapamycin-ELUTING STENTS: PP. 2.73
  3212. Preparation and production efficiency ofย Rapamycinย ointment
  3213. The influence of coronary stenting withย Rapamycin-eluting stents on the number of circulating CD4+ CD25high+ regulatory T-cells
  3214. Effect ofย Rapamycinย on Phenotype of Vascular Smooth Muscle Cell and Arterial Intimal Hyperplasia in Rat Cardiac Allograft
  3215. Mammalian target ofย Rapamycinย inhibitors in clinical practice: Case reports of everolimus in renal cell carcinoma
  3216. Application of stereocontrolled aldol coupling to synthesis of segments of immunosuppressants FK-506 andย Rapamycin
  3217. Abstract C63: Biological characterization of GSK2126458, a novel and potent inhibitor of phosphoinositide 3โ€kinase and the mammalian target ofย Rapamycinย (mTOR)
  3218. Current perspectives in metastatic renal cell carcinoma treatment: the role of mammalian target ofย Rapamycinย (mTOR)ย inhibition
  3219. Rapamycinย decreases proinflammatory and profibrogenic gene expression in experimental NASH
  3220. Expression of mammalian target ofย Rapamycinย and eIF4E signal pathway in cerebral glioma and its clinical significance [J]
  3221. Conditional protein stabilization via the small molecules Shld-1 andย Rapamycinย increases the signal-to-noise ratio with tet-inducible gene expression
  3222. A case of Kaposiโ€™s sarcoma in theย Rapamycinย era
  3223. OSI-027, a potent and selective small moleculeย mTORC1/mTORC2 kinase Inhibitor is mechanistically distinct fromย Rapamycin
  3224. eIF4E Expression Predicts Apoptosis in Response to Epidermal Growth Factor Receptorย inhibitionย and Mammalian Target ofย Rapamycinย inhibitionย in Triple Negative โ€ฆ
  3225. Rapamycinย and PD98059 collaborative inhibit mammalian target ofย Rapamycinย pathway in the prevention and treatment of mouse colorectal cancer
  3226. Effect ofย Rapamycinย on the growth of hepatocellular carcinoma in nude mice
  3227. Rapamycin-based GvHD prophylaxis after T-cell replete unmanipulated haploidentical peripheral stem cell transplantation for advanced leukaemias: preliminary โ€ฆ
  3228. Effect ofย Rapamycinย administration in humans on the skeletal muscle protein anabolic response to essential amino acid ingestion
  3229. Differential Regulation of TLR4-Mediated TNF-a Release by Mammalian Target ofย Rapamycinย and Glycogen Synthase Kinase-3 in Alveolar Macrophages from โ€ฆ
  3230. A newly developedย Rapamycin-eluting stent with a biodegradable polymer reduces neointimal formation while allowing greater endothelialization
  3231. CONVERSION TO LOW DOSE TACROLIMUS ORย Rapamycinย 3 MONTHS AFTER KIDNEY TRANSPLANT: A PROSPECTIVE, PROTOCOL BIOPSY GUIDED STUDY โ€ฆ
  3232. The Effect ofย Rapamycinย on Cardiac Allograft Vasculopathy in Rats
  3233. Abstract A94: effects of different modes of calorie restriction on mammalian target ofย Rapamycinย (mTOR) and IGF-I signaling pathways in mammary fat pads and tumors
  3234. Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological โ€ฆ
  3235. Role ofย Rapamycinย in renal ischemia-reperfusion injury
  3236. Symbol Domesticย Rapamycin-eluted stent for treatment of acute myocardial infarction in 108 cases
  3237. Rapamycinย Used in Kidney Transplantation Patients in China: A Meta-analysis of Clinical Curative Effects
  3238. Conversion toย Rapamycinย in liver transpant recipients with renal insufficiency
  3239. Genomewide Profiling ofย Rapamycinย Sensitivity in Saccharomyces cerevisiae on Synthetic Medium
  3240. Effect ofย Rapamycinย (serolimus) on in vitro cultured human oral mucosa keratinocytes
  3241. Effects ofย Rapamycinย and paclitaxel on different human prostate cancer cells and xenografts
  3242. The Generation of Novel Fluorinatedย Rapamycinย Analogues
  3243. Treg andย Rapamycinย effects on humoral immunity in young and old mice (84.12)
  3244. EXPERIENCE WITHย Rapamycinย IN PEDIATRIC LIVER TRANSPLANTATION: 1434
  3245. Inhibitory effect ofย Rapamycinย on proliferation of H_ (22) hepatic cancer in mice
  3246. Effect ofย Rapamycinย on Postoperative Fibrosis After Filtration Surgery in a Rabbit Model
  3247. The mammalian target ofย Rapamycinย in translation and folding
  3248. Effect ofย Rapamycinย on the proliferation and apoptosis of glomerular mesangial cells
  3249. Transcriptional Profile Changes Induced byย Rapamycinย in Breast Cancer Maintained in Organ Culture.
  3250. Ex Vivo Manufacture ofย Rapamycin-Resistant Human Th1/Tc1 Cells.
  3251. Effect ofย Rapamycinย on regulator T cells induced by TGF-ฮฒ1 in vitro
  3252. Study of long-term safety and efficacy of domestic Firebirdย Rapamycin-eluting stent
  3253. The Role of Mammalian Target ofย Rapamycinย in the Early Development of Mouse Zygotes
  3254. Efficacy ofย Rapamycinย drug-eluting stents in elderly patients with coronary heart disease
  3255. Insights into hepatic carcinogenesis: The effect ofย Rapamycinย on rat liver cell lines
  3256. Rapamycinย combined with cisplatin in inhibiting the proliferation of ovarian cancer SKOV-3 cells [J]
  3257. Development of Selective Inhibitors of the Mammalian Target ofย Rapamycin
  3258. Rapamycinย is a potent inhibitor of skin tumor promotion by TPA
  3259. Antiproliferative and antiangiogenic effect ofย Rapamycinย on ADPKD cystic lining epithelial cells
  3260. Abstract B141: Effects of AZD8055, a novelย mTORย kinase inhibitor, in human cancer cells developing resistance toย Rapamycin
  3261. Abstract A41: Evaluation of maximum tolerated dose of aerosolizedย Rapamycinย in A/J mice
  3262. Rapamycinย combined with nimuatine suppresses growth and proliferation of human U87MG glioma cells
  3263. Effect ofย mTORย inhibitionย byย Rapamycinย on promotion of skin tumors in BK5. Aktwt transgenic mice
  3264. Characterization of the Effects and Functions of Sumoylation Throughย Rapamycin-Mediated Heterodimerization
  3265. Black and white:ย Rapamycinย as a regulator of cardiacย mTORย signaling
  3266. Immunomodulatory Effect ofย Rapamycinย on Innate Immune Response Genes
  3267. Clenbuterol increases PGC1a promoter activity via aย Rapamycinย sensitive mechanism
  3268. Active-Siteย inhibitionย of the Mammalian Target ofย Rapamycin
  3269. Effect ofย Rapamycinย on cell prolification of glomerular mesangial cells by high glucose
  3270. The role of mammalian target ofย Rapamycinย complex 1 in hepatic physiology and disease
  3271. Anti-Leukemia Effect ofย Rapamycinย Alone or Plus Daunorubicin on Acute Lymphoblastic Leukemia Cell Lines
  3272. Rapamycinย reduces primary effusion lymphoma progression by targeting VEGF production and VEGF responses
  3273. A Combined Approach of Classical Mutagenesis and Rational Metabolic Engineering for the Improved Production ofย Rapamycinย in Streptomyces hygroscopicus โ€ฆ
  3274. Rapamycin-Induced Abundance Changes in the Proteome of Budding Yeast
  3275. Inhibitory effect ofย Rapamycinย on human renal tubular epithelial-myofibroblast transition
  3276. Rapamycinย sensitizes Jurkat T-ALL cells to dexamethasone-induced apoptosis
  3277. Effects ofย Rapamycinย on cell proliferation and apoptosis of melanoma B-16 cells
  3278. The influence ofย Rapamycinย combined with 5-Aza-cdR to interfere in the in vitro culture of MCF-7 cell line
  3279. Mammalian Target ofย Rapamycinย Signaling in Regulation of Aging of Human RPE
  3280. The therapeutic value ofย Rapamycinย in a novel mouse model for tuberous scelrosis
  3281. Novel therapeutic strategy for breast cancer: mammalian target ofย Rapamycinย inhibition
  3282. Effects ofย Rapamycinย on growth andย mTOR/4EBP1 Signalling Pathway in Xenograft of Esophageal Squamous Cell Carcinoma
  3283. Comparison ofย Rapamycinย and Mitomycin for Reduction of Postoperative Fibrosis After Filtration Surgery in a Rabbit Model
  3284. Rapamycinย enhances G protein signaling in the budding yeast Saccharomyces Cerevisiae
  3285. Pharmacokinetics characterization ofย Rapamycinย ointment in rabbit aqueous humor
  3286. Effects ofย Rapamycinย on nephropathy and expression of VEGF and VEGF receptors in PAN nephritic mice [J]
  3287. โ€ฆย Rapamycinย Combination toward Colon Cancer Cells In vivo and In vitro Is Mediated through Cooperative Modulation of the MammalianTarget ofย Rapamycinย โ€ฆ
  3288. The Regulation of STAT1 Nuclear Content by Mammalian Target ofย Rapamycin
  3289. Mammalian Target ofย Rapamycinย Regulates STAT1 Localization in Lung Epithelial Cells.
  3290. Rapamycin-Induced Allograft Tolerance: Elucidating Mechanisms and Biomarker Discovery
  3291. Rapamycinย prevents the postโ€exercise increase in protein synthesis and alters cell signaling in human skeletal muscle
  3292. Theย Rapamycin-sensitive phosphoproteome reveals that TOR controls PKA 3 toward some but not all substrates 4
  3293. CLONING AND CHARACTERIZATION OF THE PARTIALย Rapamycin-BIOSYNTHETIC GENE CLUSTER FROM ACTINOPLANES SP. N902-109
  3294. Expression of mammalian target ofย Rapamycin/P70S6K in pathologic scars
  3295. Rapamycinโ€sensitive Coโ€localization ofย mTORย to the Mitotic Spindle
  3296. Abstract B143: Distinct antitumor mechanisms of VEGFR inhibitor tivozanib (AVโ€951) andย mTORย inhibitorย Rapamycinย support rational combination for solid tumors to โ€ฆ
  3297. Effectiveness ofย Rapamycinย drug-eluting stent (Excel stent) in treatment of patients with coronary artery disease
  3298. Defining the clinical role of the mammalian target ofย Rapamycinย (mTOR) in lung cancer
  3299. BETA-CATENIN TARGET GENES ARE UPREGULATED DURING PARTIAL BLADDER OUTLET OBSTRUCTION AND INHIBITED BYย Rapamycin
  3300. Effect ofย Rapamycinย on TGF-ฮฒ1-induced epithelial-mesenchymal transition in LoVo colonic adenocarcinoma cells
  3301. Tolerability of theย mTORย inhibitorย Rapamycinย in cirrhotic patients with advanced hepatocellular carcinoma
  3302. Clinical Application of Domesticย Rapamycin-Eluting Stent in the Emergency Intervention of Acute Coronary Syndrome (ACS)
  3303. Rapamycin-Induced Insulin Resistance Is Mediated byย mTORC2 Loss
  3304. Effect ofย Rapamycinย on regulating Toll-like receptor-4 gene expression in rats with acute liver failure
  3305. The influence ofย Rapamycinย on expression of CCR7 in the rats with renal fibrosis induced by adriamycin
  3306. Rapamycinย induces proliferation of CD4~+ CD25~+ FoxP3~+ T regulatory cells in rats
  3307. Mammalian target ofย Rapamycinย complex 2 regulates helper T cell differentiation and function (47.31)
  3308. BLADDER SMOOTH MUSCLE CELL GROWTH IS MEDIATED BY MAMMALIAN TARGET OFย Rapamycinย (mTOR)
  3309. Expression and significance of phosphorylation-mammalian target ofย Rapamycinย in endometrial carcinoma
  3310. High Levels Of Mammalian Target Ofย Rapamycinย (mTOR) In Pulmonary Hypertension
  3311. Transscleral Passive Delivery ofย Rapamycinย in Rabbit Using a Visulexยฎ Topical Application Device
  3312. Inhibitory effect ofย Rapamycinย on connective tissue growth factor-stimulated cell proliferation and fibronectin secretion in myofibroblasts
  3313. Treatment of malignant gliomas with systemicย Rapamycinย and convection-enhanced delivery of nanoliposomal CPT-11
  3314. e0519ย Rapamycinย suppress Krรœppel-Like Factor 2 expression: mechanism of endothelial dysfunction associated with drug-eluting stents
  3315. The mammalian target ofย Rapamycinย inhibitor RAD001 (everolimus) in early breast cancer
  3316. Mammalian target ofย Rapamycinย inhibitors for the targeted therapy of non-small cell lung cancer
  3317. Chronicย Rapamycinย Therapy Ameliorates Hypertrophy and Systolic Dysfunction in Severe Chronic Heart Failure Due to Pressure Overload
  3318. Physiologic Stimulation Of Bladder Smooth Muscle Cell Growth Is Mediated By Mammalial Target Ofย Rapamycinย (mTOR)
  3319. Treatment of Non-left Main Bifurcation Lesions Using theย Rapamycin-Eluting Stent
  3320. Determination of Encapsulation Efficiency ofย Rapamycin-loaded Poly (lactic-co-glycolic) acid Nanoparticles by HPLC
  3321. Elucidation of chemopreventive effects of aerosolizedย Rapamycinย and dietary myoinositol by mechanistic biomarkers in mouse lung
  3322. Expansion of CD3+/CD4+/CD25+/Foxp3+ T cells inย Rapamycin-treated lupus patients (143.52)
  3323. Mammalian target ofย Rapamycinย (mTOR) inhibitors with therapeutic potential for colitis
  3324. PATHOLOGICAL ANGIOGENESIS IN VASCULAR TUMORS IS DRIVEN BY AKT1 AND INHIBITED BY TOPICALย Rapamycin
  3325. Combination Of Simvastatin Andย Rapamycinย Abrogates TSC2-null Tumor Growth In Nude Mice And Improves Animal Survival
  3326. Pathological angiogenesis in vascular tumors is driven by endothelial Akt1 and inhibited byย Rapamycin
  3327. Effect of intravenous injection of apoptotic cells combined withย Rapamycinย on regulatory T cells in rhesus monkey
  3328. Rapamycinย Inhibits Store-Operated Ca2+ Entry in Cells Isolated from Endarterectomized Tissues of Patients with Chronic Thromboembolic Pulmonary Hypertension.
  3329. Immune regulatory effect ofย Rapamycinย and cyclosporine A on experimental corneal allograft survival
  3330. Effect ofย Rapamycinย Eluting Stent forย inhibitionย of Neointimal Hyperplasia in Diabetic Porcine Model
  3331. Supplemental Information Mechanisms of Life Span Extension byย Rapamycinย in the Fruit Fly Drosophila melanogaster
  3332. Effects of high glucose andย Rapamycinย intervention on expression of type โ…ฃ collagen and matrix metalloproteinase-9 in podocytes
  3333. Cigarette Smoke Andย Rapamycinย Up-regulate Matrix Metalloproteinase-1 Expression In Endothelial Cells Throughย mTORย Activation
  3334. Preparation and in vitro release study ofย Rapamycinย in poly (lactic-co-glycolic) acid microsphere for topical administration
  3335. PDGFR alpha is overexpressed in synovial sarcomas and can mediateย Rapamycinย induced Akt activation
  3336. Enhanced tumor cytotoxicity of a combinational therapy using liposomal copper-doxorubicin,ย Rapamycin, and ultrasound
  3337. Rapamycin-CONDITIONED HUMAN DENDRITIC CELLS EXHIBIT INCREASED IL-12P70 PRODUCTION UPON EXPOSURE TO PRO-INFLAMMATORY โ€ฆ
  3338. Rapamycinย eye drops inhibit rat corneal neovascularization: Role of vascular endothelial growth factor and inflammatory factorโ˜†
  3339. The mammalian target ofย Rapamycinย signaling pathway in bovine mammary epithelial cells
  3340. Characterisation of the effects and mechanism of action ofย Rapamycinย and genistein on acute myeloid leukemia using high-throughput techniques
  3341. New Drug Development in Sarcoma: Exploration of Novel Targets, Particularly the Mammalian Target ofย Rapamycinย (mTOR) Pathway
  3342. 45A: TARGETED SITE SPECIFIC IMMUNOSUPPRESSION WITH TOPICALย Rapamycinย AND MYCOPHENOLIC ACID IN COMPOSITE TISSUE โ€ฆ
  3343. 1, 4-phenylenebis (methylene) selenocyanate (p-XSC) inhibits mammalian target ofย Rapamycinย complex 2 (mTORC2) signaling in prostate cancer cells
  3344. Pre-clinical and Clinical Study Results for the Coractoโ„ขย Rapamycin-eluting Stentโ€“A New-generation Drug-eluting Stent
  3345. The Protective Effect of mammalian Target ofย Rapamycinย (mTOR) in Cisplatin Induced Nephropathy
  3346. Contact-dependent suppression pathways in non-human primate Tregs expanded ex vivo in the presence ofย Rapamycinย (141.36)
  3347. The effects of l-leucine, contractions, andย Rapamycinย on the Akt/mTORย pathway in rat skeletal muscle
  3348. Rapamycinย IMPAIRS PROLIFERATION OF TRANSPLANTED ISLET BETA CELLS: 791
  3349. Rapamycinย inhibits epidermal cell proliferation in a xenograft model of tuberous sclerosis skin tumors
  3350. Effect of the combination of retinoic acid andย Rapamycinย on cerebellar granule cell and medulloblastoma proliferation
  3351. Nutrient signaling, mammalian target ofย Rapamycinย and ovine conceptus development
  3352. Effect of combination of CCR5 antisense peptide nucleic acid and lose-doseย Rapamycinย on islet allograft survival
  3353. Rapamycinย inhibits cyst growth, IGF-1-mediated VEGF secretion and cell proliferation in polycystin-2 defective mice
  3354. Is Oralย Rapamycinย Plus Bare Metal Stents a Feasible Alternative to Drugโ€Eluting Stents? Lessons Learned from Argentina Observational and Randomized Studies โ€ฆ
  3355. Rapamycin-Induced Autophagy Generates Anti-Apoptotic Th1/Tc1 Cells That Mediate Increased Xenogeneic Gvhd.
  3356. Rapamycinย impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism in the Krebs cycle
  3357. Combination of antagonists of growth hormone-releasing hormone antagonist (GHRH) withย Rapamycinย as a potential therapy in human breast cancers.
  3358. Role of mammalian target ofย Rapamycinย signalling in bone destruction by gingival squamous cell carcinoma
  3359. Rapamycinย potentiates the effects of paclitaxel in uterine papillary serous carcinoma (UPSC) cells throughย inhibitionย of cell proliferation and induction of apoptosis
  3360. Symbol Effect ofย Rapamycin-poly (lactide-acid)/magnetic microsphere composite materials on the proliferation of vascular smooth muscle cells
  3361. Retinoblastoma Tumor Burden Control: Periocular m-TOR Inhibitorย Rapamycinย Decreases Tumor Burden in Advanced LHBETATAG Murine Retinoblastoma
  3362. Effects of Mycophenolic Acid andย Rapamycinย on Toll-like Receptor Expression in Hypoxic Human Proximal Tubular Epithelial Cells
  3363. The Impact of Iron Deficiency During Development on Mammalian Target ofย Rapamycinย Signaling, Neuronal Structure, and Learning and Memory Behavior
  3364. Mammalian Target ofย Rapamycin: A Bump in the Pathway to NF-ฮบB Activation and ICAM-1 Expression in Endothelial Cells.
  3365. Increased Frequency Of Regulatory T-Cells And Selection Of Highly Potent CD62L+ Cells During Treatment Of Human Lung Recipients Withย Rapamycin
  3366. The IGF-1 receptor targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes withย Rapamycinย in models of childhood sarcoma
  3367. Targeting mammalian target ofย Rapamycinย (mTOR) signaling in the Han: SPRD rat, a model for polycystic kidney disease
  3368. Chemical Genetic Dissection of TOR Signaling Through Identification and Characterization of Small Molecule Enhancers ofย Rapamycin
  3369. Mammalian Target ofย Rapamycinย Signaling and the Suprachiasmatic Circadian Clock
  3370. Abstract# 3712: OXA-01, a novel potentย mTORC1/TORC2 inhibitor displays improved anti-tumor activity in comparison toย Rapamycin, anย mTORC1 selective inhibitor
  3371. inhibitionย of mammalian target ofย Rapamycinย induces phenotypic reversion in three-dimensional cultures of malignant breast epithelial cells
  3372. Rapamycinย mediatedย inhibitionย ofย mTORย prevents postprandial activation of the unfolded protein response and upregulation of fatty acid synthase
  3373. Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression andย Rapamycinย treatment in S. cerevisiae
  3374. Use ofย Rapamycinย Reveals Evidence of the Physiological Roles of FKBP12 and FKBP12. 6 In Cardiac Excitation-Contraction Coupling
  3375. e0520 Statin effects in stent thrombosis induced byย Rapamycinย releasing from drug-eluting stents through Krรœppel-Like Factor 2 overexpression
  3376. Rapamycinย enhanced in vitro and in vivo activity of dexamethasone against acute lymphoblastic leukemia and lymphoma preclincal models viaย inhibitionย of p70S6 โ€ฆ
  3377. Human T Cellย Rapamycinย Resistance And Th1/Tc1 Polarization Augment Xenogeneic Graft-Versus-Host Disease
  3378. Abstract# 4363:ย inhibitionย of mammalian target ofย Rapamycinย (mTOR) in advanced pancreatic cancer-the results of two prospective phase II studies.
  3379. In vitro enhancing oxidative phosphorylation byย Rapamycinย in proliferative CD8+ T cells during antigenic priming augments the generation of long-lived memory T cells โ€ฆ
  3380. Comparasion of therapeutic effects of Chineseย Rapamycin-eluting stent and imported paclitaxel-eluting stent in treatment of acute myocardial infarction
  3381. Generation of tolerogenic human DC throughย Rapamycinย conditioning and genetic modification with HLA-G.
  3382. Prolonged Exposure of Myeloid Dendritic Cells Toย Rapamycinย enhances LPS-induced IL-12p70 production, but does not promote Th1 responses (141.29)
  3383. The mammalian target ofย Rapamycinย mediates the angiogenic and chemotactic effects of leptin in human hepatic stellate cells.
  3384. Calorie restriction andย Rapamycin, but not exercise, inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity
  3385. Abstract# LB-135: Grapefruit juice significantly increases bioavailability of weeklyย Rapamycinย (sirolimus)-evidence of safety and activity in a phase 1 study
  3386. Mammalian Target ofย Rapamycinย (mTOR)-mediated Effect on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
  3387. Vitamin K_3 induces autophagy in HeLa cells through downregulating the mammalian target ofย Rapamycinย (mTOR) pathway
  3388. Pharmacodynamic (PD) study of pre-prostatectomyย Rapamycinย in men with advanced localized prostate cancer (PC): A DOD Prostate Cancer Clinical Trials โ€ฆ
  3389. Effects of high-fat vs. low-fat diets on mammalian target ofย Rapamycinย signaling and metabolic measures in spontaneously hypertensive rats
  3390. Anti-liver fibrotic effect of Salvia miltiorthiza and Shugan-Huayu powder combining with or withoutย Rapamycinย in animal models.
  3391. Rapidly Inducible Protein Modification Usingย Rapamycin-mediated Complementation Of Tobacco Etch Virus (TEV) Protease
  3392. Modulatory Role of Mammalian Target ofย Rapamycinย in Regulating Endothelial ICAMโ€1 Expression and Lung PMN Recruitment
  3393. Erratum: Mammalian target ofย Rapamycinย activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial โ€ฆ
  3394. Rapamycinย AND MYCOPHENOLIC ACID, BUT NOT CYCLOSPORIN A, IMPAIR HUMAN NK CELL CYTOLYTIC ACTIVITY DUE TO DIFFERENTIAL EFFECTS ON โ€ฆ
  3395. 198 Modulation of CCR5 density with low doses of the transplant drugย Rapamycinย sensitizes Vicriviroc-resistant R5 HIV-1
  3396. Rapamycinย and IL-2 Prevents Lethal Acute Graft-Versus Host Disease by Expansion of Donor Type CD4+CD25+Foxp3+ Regulatory T Cells.
  3397. Abstract# 4648:ย Rapamycinย inhibits tube formation of lymphatic endothelial cells by targeting TORC1-mediated expression of Flt4
  3398. Abstract LB-74: A high-throughput RNAi sensitization screen ofย Rapamycinย identifies targets for rational drug combination strategies
  3399. Abstract# 2770: Over-expression of the mammalian target ofย Rapamycinย (mTOR): a novel biomarker for poor survival in resected early stage non-small cell lung cancer
  3400. Abstract# 2014: ATP competitive inhibitors of the mammalian target ofย Rapamycinย (mTOR): Design and synthesis of novel, highly selective pyrazolopyrimidines with โ€ฆ
  3401. The Mammalian Target ofย Rapamycinย (mTOR) Is a Novel Regulator of HMW-Hyaluronan-Mediated Pulmonary Endothelial Barrier Enhancement.
  3402. COMBINED ADMINISTRATION OF A NOVEL MUTANT TGF-ฮฒ1/FC ANDย Rapamycinย MODULATES THE IMMUNE BALANCE BETWEEN TREG AND TH17 AND โ€ฆ
  3403. CD28: FC ANDย Rapamycinย CAN PREVENT TH17-MEDIATED ALLOGRAFT REJECTION IN MOUSE PANCREATIC ISLET TRANSPLANTATION MODEL: 700
  3404. Androgen receptor antagonist bicalutamide sensitizes androgen-independent prostate cancer cells toย mTORย inhibitorย Rapamycinย by regulating phosphorylation of โ€ฆ
  3405. Abstract# 1735:ย Rapamycinย inhibits hyperactivation ofย mTORC1 signaling in a novel xenograft model of tuberous sclerosis complex skin tumors
  3406. ET-29. ONCOLYTIC VIRUS COMBINED WITHย Rapamycinย TARGETING BRAIN TUMOR-INITIATING CELLS
  3407. โ€ฆ Multicenter phase I clinical trial of an insulin like growth factor (IGFโ€R) inhibitor (IMCโ€A12) in combination with a mammalian target ofย Rapamycinย (mTOR) inhibitor (CCI โ€ฆ
  3408. Mouse Oocytes Promote the Mechanistic Target ofย Rapamycinย (Serine/Threonine Kinase,ย mTOR) Pathway in Cumulus Cells by Suppressing the Expression of DNA โ€ฆ
  3409. โ€ฆ oral protein: timeโ€dependent concordance/discordance between muscle protein synthesis (MPS) and mammalian target ofย Rapamycinย (mTOR)โ€associated signaling
  3410. Relationship between expression of mutant type glutathione S-transferase theta-1 gene and reactivity ofย Rapamycinย in myelodysplastic syndrome
  3411. Rapamycinย CONDITIONED DENDRITIC CELLS FOR IN VITRO DIFFERENTIATION OF DONOR-SPECIFIC CD4+ CD25+ FOXP3+ REGULATORY T CELLS FOR โ€ฆ
  3412. โ€ฆ DEVELOPMENT OF CD8+ CD44+ CD62L+ MEMORY T CELLS PROMOTE SPECIFIC TOLERANCE TO CARDIAC ALLOGRAFTS FOLLOWINGย Rapamycinย โ€ฆ
  3413. Abstract# 4050: Increased cytotoxicity with nifurtimox andย Rapamycinย combination therapy in neuroblastoma.
  3414. The Effect of Insulin-like Growth Factor 1 (IGF-1) and Exercise on the Protein Expression of Mammalian Target ofย Rapamycinย (mTOR) and Androgen Receptor (AR) in โ€ฆ
  3415. Abstract# 3711: Superior cellular anti-tumor effects of a dualย mTORC1/mTORC2 kinase inhibitor OXA-01 relative to theย mTORC1 inhibitorย Rapamycin
  3416. Erratum 2: Testosterone induces cardiomyocyte hypertrophy through mammalian target ofย Rapamycinย complex 1 pathway
  3417. Erratum 2: Testosterone induces cardiomyocyte hypertrophy through mammalian target ofย Rapamycinย complex 1 pathway (vol 202, pg 299, 2009)
  3418. Abstract# 156: Is irinotecan andย Rapamycinย combination, targetingย mTOR/HIF-1 alpha axis, a new effective therapy in high grade brain tumors?
  3419. Intra-Nuclear Function for PP2A Phosphatase: Pph21/22 Are Required forย Rapamycin-Induced GATA Factor Binding to the DAL5 Promoter in Yeast
  3420. Activating transcription factor 4 negatively regulates the mammalian target ofย Rapamycinย via Redd1 expression in response to 2-deoxyglucose
  3421. Abstract# 5237: The combination ofย Rapamycinย and bicalutamide induce apoptosis in prostate cancer cells by simultaneously inhibiting theย mTORC1/eIF4 and AR โ€ฆ
  3422. TORC1/2 inhibitors have more potent anti-leukemic efficacy and are less immunosuppressive thanย Rapamycin
  3423. Abstract# 2824: The Src inhibitor AZD0530 enhances the anti-tumor effect ofย Rapamycinย in hepatocellular carcinoma (HCC) cells
  3424. Abstract LB-159: An orthotopic model of head and neck squamous carcinoma reveals thatย mTORย inhibitionย withย Rapamycinย halts lymph node metastasis
  3425. Abstract# 3842: High expression ofย mTORย (mammalian target ofย Rapamycin) is associated with better outcome in non-small cell lung cancer
  3426. Abstract# 1079: CD133 expression is affected byย Rapamycinย in cancer cells.
  3427. Abstract# 2879:ย inhibitionย of mammalian target ofย Rapamycinย as a therapeutic strategy in the management of bladder cancer
  3428. Abstract# 3757: Antiproliferative effects ofย Rapamycinย and doxorubicin combination on human Erbb2 overexpressing breast epithelial cell lines.
  3429. Abstract# 2818: Growthย inhibitionย of human breast cancer cells with an iron chelator and a dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor
  3430. Abstract# 2302: NVP-BEZ235 a dual inhibitor of phosphatidylinositol 3-Kinase (PI3 Kinase) and mammalian target ofย Rapamycinย (mTOR) potently enhances the effects โ€ฆ
  3431. Liposomal KRN7000 (RGI-2001) Synergizes with Low-Doseย Rapamycinย in Preventing GvHD by promoting expansion of naturally-Occurring CD4+FOXP3+ โ€ฆ
  3432. Abstract P3-14-17: Trastuzumab (H) andย Rapamycinย (R) for Treatment of HER-2 Overexpressing Metastatic Breast Cancer (BC) with Prior Disease Progression on H โ€ฆ
  3433. โ€ฆ : HQO-0601, an amide-containing 3, 4-dihydroquinolinone derivative, against human hematologic malignancies throughย inhibitionย of mammalian target ofย Rapamycinย โ€ฆ
  3434. Rapamycinย slows aging in mice
  3435. Fighting neurodegeneration withย Rapamycin: mechanistic insights
  3436. Target ofย Rapamycinย (TOR) in nutrient signaling and growth control
  3437. Rapamycinย and glucose-target ofย Rapamycinย (TOR) protein signaling in plants
  3438. Rapamycinย passes the torch: a new generation ofย mTORย inhibitors
  3439. Rapamycin-induced insulin resistance is mediated byย mTORC2 loss and uncoupled from longevity
  3440. Autophagy activation byย Rapamycinย reduces severity of experimental osteoarthritis
  3441. Protein translocation as a tool: The currentย Rapamycinย story
  3442. Relieving autophagy and 4EBP1 fromย Rapamycinย resistance
  3443. Chronicย inhibitionย of mammalian target ofย Rapamycinย byย Rapamycinย modulates cognitive and non-cognitive components of behavior throughout lifespan in mice
  3444. Paradoxical aspects ofย Rapamycinย immunobiology in transplantation
  3445. Rapamycinย andย mTOR: a serendipitous discovery and implications for breast cancer
  3446. Rapamycinย increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
  3447. TOR signaling andย Rapamycinย influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
  3448. Rapamycinย for treating Tuberous sclerosis and Autism spectrum disorders
  3449. The mammalian target ofย Rapamycinย regulates cholesterol biosynthetic gene expression and exhibits aย Rapamycin-resistant transcriptional profile
  3450. A photocleavableย Rapamycinย conjugate for spatiotemporal control of small GTPase activity
  3451. Target ofย Rapamycinย signaling regulates metabolism, growth, and life span in Arabidopsis
  3452. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
  3453. Rapamycinย reverses impaired social interaction in mouse models of tuberous sclerosis complex
  3454. Rapamycinย and other longevityโ€promoting compounds enhance the generation of mouse induced pluripotent stem cells
  3455. mTORย andย Rapamycinย in the kidney: signaling and therapeutic implications beyond immunosuppression
  3456. Inducing autophagy byย Rapamycinย before, but not after, the formation of plaques and tangles ameliorates cognitive deficits
  3457. โ€ฆ enhances the anti-tumor activity of theย mTORย inhibitorย Rapamycinย in multiple breast cancer cell lines mainly by suppressingย Rapamycin-induced AKT signaling
  3458. Common toxicities of mammalian target ofย Rapamycinย inhibitors
  3459. Topicalย Rapamycinย therapy to alleviate the cutaneous manifestations of tuberous sclerosis complex
  3460. Rapamycinย treatment augments motor neuron degeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis
  3461. Activating mutations of TOR (target ofย Rapamycin)
  3462. Rapamycinย reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
  3463. Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs ฮฒ-cell function
  3464. Mammalian target ofย Rapamycin: a signaling kinase for every aspect of cellular life
  3465. Mammalian target ofย Rapamycin: a central node of complex signaling cascades
  3466. Induction of tolerance to factor VIII by transient coโ€administration withย Rapamycin
  3467. Once again onย Rapamycin-induced insulin resistance and longevity: despite of or owing to
  3468. Haploinsufficiency of target ofย Rapamycinย attenuates cardiomyopathies in adult zebrafish
  3469. Stability of humanย Rapamycin-expanded CD4+ CD25+ T regulatory cells
  3470. Autophagy and cardiovascular aging: lesson learned fromย Rapamycin
  3471. Rapamycinย extends lifespan and delays tumorigenesis in heterozygous p53+/โˆ’ mice
  3472. A pulseย Rapamycinย therapy for infantile spasms and associated cognitive decline
  3473. Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response toย Rapamycinย in yeast
  3474. Rapamycinย protects against myocardial ischemiaโ€“reperfusion injury through JAK2โ€“STAT3 signaling pathway
  3475. Mammalian target ofย Rapamycinย and the kidney. I. The signaling pathway
  3476. The ketogenic diet inhibits the mammalian target ofย Rapamycinย (mTOR) pathway
  3477. Preventive and therapeutic effects ofย Rapamycin, a mammalian target ofย Rapamycinย inhibitor, on food allergy in mice
  3478. Shedding new light on neurodegenerative diseases through the mammalian target ofย Rapamycin
  3479. Lifelongย Rapamycinย administration ameliorates ageโ€dependent cognitive deficits by reducing ILโ€1ฮฒ and enhancing NMDA signaling
  3480. Mammalian target ofย Rapamycinย up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
  3481. Mammalian target ofย Rapamycinย signaling in diabetic cardiovascular disease
  3482. Rapamycinย promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice
  3483. Folate-conjugatedย Rapamycinย slows progression of polycystic kidney disease
  3484. Mammalian target ofย Rapamycinย (mTOR) signaling network in skeletal myogenesis
  3485. Rapamycinย suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy
  3486. Chronicย mTORย inhibitionย byย Rapamycinย induces muscle insulin resistance despite weight loss in rats
  3487. Wound healing complications and the use of mammalian target ofย Rapamycinย inhibitors in kidney transplantation: a critical review of the literature
  3488. Rapamycinย increases oxidative stress response gene expression in adult stem cells
  3489. inhibitionย of mammalian target ofย Rapamycinย reduces epileptogenesis and bloodโ€“brain barrier leakage but not microglia activation
  3490. Rapamycinย As an Antiaging Therapeutic?: Targeting Mammalian Target ofย Rapamycinย to Treat Hutchinsonโ€“Gilford Progeria and Neurodegenerative Diseases
  3491. Successful treatment of angiofibromata of tuberous sclerosis complex withย Rapamycin
  3492. Rapamycinย protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats
  3493. Rapamycinย Causes Upregulation of Autophagy and Impairs Islets Function Bothโ€‚In Vitroโ€‚andโ€‚In Vivo
  3494. Therapeutic role of mammalian target ofย Rapamycinย (mTOR)ย inhibitionย in preventing epileptogenesis
  3495. Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-doseย Rapamycinย impairs autophagic flux in โ€ฆ
  3496. Prevention of age-related macular degenerationโ€“like retinopathy byย Rapamycinย in Rats
  3497. Mammalian target ofย Rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimerโ€™s disease?
  3498. The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target ofย Rapamycinย (mTOR) pathway
  3499. Current and future directions in mammalian target ofย Rapamycinย inhibitors development
  3500. Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy withย Rapamycin
  3501. Target ofย Rapamycinย regulates development and ribosomal RNA expression through kinase domain in Arabidopsis
  3502. Mammalian target ofย Rapamycinย complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids
  3503. The PI3K/Akt/mTORย pathway is activated in murine lupus nephritis and downregulated byย Rapamycin
  3504. inhibitionย of mammalian target ofย Rapamycinย augments lipopolysaccharide-induced lung injury and apoptosis
  3505. New nanoformulation ofย Rapamycinย Rapatar extends lifespan in homozygous p53โˆ’/โˆ’ mice by delaying carcinogenesis
  3506. Combinatorial effects of lapatinib andย Rapamycinย in triple-negative breast cancer cells
  3507. Phase II study of the mammalian target ofย Rapamycinย inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas
  3508. Impaired autophagy in neurons after disinhibitionย of mammalian target ofย Rapamycinย and its contribution to epileptogenesis
  3509. Rapamycinย delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmannโ€“Strรคusslerโ€“Scheinker disease
  3510. Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target ofย Rapamycinย (mTOR) complex 2
  3511. Rapamycinย reverses elevatedย mTORC1 signaling in lamin A/Cโ€“deficient mice, rescues cardiac and skeletal muscle function, and extends survival
  3512. Retinoic acid andย Rapamycinย differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells
  3513. Rapamycinย increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae
  3514. Review of cytomegalovirus infection findings with mammalian target ofย Rapamycinย inhibitor-based immunosuppressive therapy in de novo renal transplant recipients
  3515. Lowโ€Doseย Rapamycinย Treatment Increases the Ability of Human Regulatory T Cells to Inhibit Transplant Arteriosclerosis In Vivo
  3516. Stable isotope-labelling analysis of the impact ofย inhibitionย of the mammalian target ofย Rapamycinย on protein synthesis
  3517. Managing stomatitis in patients treated with Mammalian target ofย Rapamycinย inhibitors.
  3518. Rapamycinย reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndromeโ€“associated PTPN11 mutation
  3519. Rapamycinย blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug
  3520. inhibitionย of mechanistic target ofย Rapamycinย promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice
  3521. Therapeutic value of prenatalย Rapamycinย treatment in a mouse brain model of tuberous sclerosis complex
  3522. Selective pharmacogeneticย inhibitionย of mammalian target ofย Rapamycinย complex I (mTORC1) blocks long-term synaptic plasticity and memory storage
  3523. Rapamycinย slows aging in mice
  3524. Amino acids activate mammalian target ofย Rapamycinย complex 2 (mTORC2) via PI3K/Akt signaling
  3525. Suppression of replicative senescence byย Rapamycinย in rodent embryonic cells
  3526. inhibitionย of the mammalian target ofย Rapamycinย blocks epilepsy progression in NSโ€Pten conditional knockout mice
  3527. Theย mTORย inhibitorย Rapamycinย suppresses DNA double-strand break repair
  3528. Autophagy stimulation byย Rapamycinย suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis
  3529. Rapamycinย for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study
  3530. Differing effects ofย Rapamycinย or calcineurin inhibitor on Tโ€regulatory cells in pediatric liver and kidney transplant recipients
  3531. Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue byย Rapamycin
  3532. Post-treatment withย Rapamycinย does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy
  3533. Mammalian target ofย Rapamycinย and the kidney. II. Pathophysiology and therapeutic implications
  3534. Rapamycinย inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF
  3535. Optimization ofย Rapamycin-loaded acetalated dextran microparticles for immunosuppression
  3536. Rapamycinย induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity
  3537. Mammalian target ofย Rapamycinย regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 ฮฑ
  3538. Stress-responsive sestrins link p53 with redox regulation and mammalian target ofย Rapamycinย signaling
  3539. Rapamycinย ameliorates age-dependent obesity associated with increasedย mTORย signaling in hypothalamic POMC neurons
  3540. Oralย Rapamycinย in the treatment of patients with hamartoma syndromes and PTEN mutation
  3541. Oral adverse events associated with tyrosine kinase and mammalian target ofย Rapamycinย inhibitors in renal cell carcinoma: a structured literature review
  3542. Efficacy and safety of sorafenib in combination with mammalian target ofย Rapamycinย inhibitors for recurrent hepatocellular carcinoma after liver transplantation
  3543. Involvement of the mammalian target ofย Rapamycinย signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists
  3544. Nโ€acetylcysteine reduces disease activity by blocking mammalian target ofย Rapamycinย in T cells from systemic lupus erythematosus patients: A randomized, double โ€ฆ
  3545. โ€ฆ lactate dehydrogenase predicts for overall survival benefit in patients with metastatic renal cell carcinoma treated withย inhibitionย of mammalian target ofย Rapamycin
  3546. Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel,ย Rapamycin, and 17-AAG
  3547. Rapamycin-induced glucose intolerance: hunger or starvation diabetes
  3548. Induction of biogenic magnetization and redox control by a component of the target ofย Rapamycinย complex 1 signaling pathway
  3549. Rapamycinย resistance is linked to defective regulation of Skp2
  3550. Rapamycinย ameliorates kidney fibrosis by inhibiting the activation ofย mTORย signaling in interstitial macrophages and myofibroblasts
  3551. Roles of the mammalian target ofย Rapamycin,ย mTOR, in controlling ribosome biogenesis and protein synthesis
  3552. Theย mTORย inhibitorย Rapamycinย has limited acute anticonvulsant effects in mice
  3553. Multiple roles for mammalian target ofย Rapamycinย signaling in both glutamatergic and GABAergic synaptic transmission
  3554. Rapamycinย suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma
  3555. Rapamycin-induced enhancement of vaccine efficacy in mice
  3556. Regulating mammalian target ofย Rapamycinย to tune vaccination-induced CD8+ T cell responses for tumor immunity
  3557. Biosynthesis of the immunosuppressants FK506, FK520, andย Rapamycinย involves a previously undescribed family of enzymes acting on chorismate
  3558. A comprehensive review of everolimus clinical reports: a new mammalian target ofย Rapamycinย inhibitor
  3559. Selective activation of Akt1 by mammalian target ofย Rapamycinย complex 2 regulates cancer cell migration, invasion, and metastasis
  3560. Rab5 proteins regulate activation and localization of target ofย Rapamycinย complex 1
  3561. Mutations in the Arabidopsis homolog of LST8/GฮฒL, a partner of the target ofย Rapamycinย kinase, impair plant growth, flowering, and metabolic adaptation to long days
  3562. Mammalian target ofย Rapamycinย (mTOR)ย inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy
  3563. Expanding human T regulatory cells with theย mTOR-inhibitorย Rapamycin
  3564. Effects ofย Rapamycinย and TOR on aging and memory: implications for Alzheimerโ€™s disease
  3565. Naturally secreted amyloid-ฮฒ increases mammalian target ofย Rapamycinย (mTOR) activity via a PRAS40-mediated mechanism
  3566. Phospholipase D mediates nutrient input to mammalian target ofย Rapamycinย complex 1 (mTORC1)
  3567. Rapamycinย activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders
  3568. Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target ofย Rapamycinย complex 2 (TORC2) and its effector proteins Slm1 and Slm2
  3569. Rapamycinย induces Bad phosphorylation in association with its resistance to human lung cancer cells
  3570. Mycobacterial induction of autophagy varies by species and occurs independently of mammalian target ofย Rapamycinย inhibition
  3571. Third target ofย Rapamycinย complex negatively regulates development of quiescence in Trypanosoma brucei
  3572. Rapamycinย toxicity in MIN6 cells and rat and human islets is mediated by theย inhibitionย ofย mTORย complex 2 (mTORC2)
  3573. Rapamycinย attenuates airway hyperreactivity, goblet cells, and IgE in experimental allergic asthma
  3574. mTORย inhibitionย withย Rapamycinย causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes
  3575. Progeria,ย Rapamycinย and normal aging: recent breakthrough
  3576. Resveratrol inhibits inflammatory responses via the mammalian target ofย Rapamycinย signaling pathway in cultured LPS-stimulated microglial cells
  3577. High-doseย Rapamycinย induces apoptosis in human cancer cells by dissociatingย mTORย complex 1 and suppressing phosphorylation of 4E-BP1
  3578. Systemicย inhibitionย of the mammalian target ofย Rapamycinย (mTOR) pathway reduces neuropathic pain in mice
  3579. The differential effects of prenatal and/or postnatalย Rapamycinย on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis โ€ฆ
  3580. Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent ofย mTORย (mammalian target ofย Rapamycin)
  3581. Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target ofย Rapamycinย signaling
  3582. Rapamycinย and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells
  3583. Theย mTORย kinase inhibitorย Rapamycinย decreases iNOS mRNA stability in astrocytes
  3584. Insulin-like peptides and the target ofย Rapamycinย pathway coordinately regulate blood digestion and egg maturation in the mosquito Aedes aegypti
  3585. Heightened uterine mammalian target ofย Rapamycinย complex 1 (mTORC1) signaling provokes preterm birth in mice
  3586. inhibitionย of the mammalian target ofย Rapamycinย pathway byย Rapamycinย blocks cocaine-induced locomotor sensitization
  3587. Tolerance induction by exosomes from immature dendritic cells andย Rapamycinย in a mouse cardiac allograft model
  3588. Rapamycinย is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
  3589. Characterization of the metabolic phenotype ofย Rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells
  3590. Light regulation of protein dimerization and kinase activity in living cells using photocagedย Rapamycinย and engineered FKBP
  3591. Mammalian target ofย Rapamycinย signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain
  3592. Metformin promotes progesterone receptor expression viaย inhibitionย of mammalian target ofย Rapamycinย (mTOR) in endometrial cancer cells
  3593. A critical role for non-coding RNA GAS5 in growth arrest andย Rapamycinย inhibitionย in human T-lymphocytes
  3594. Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target ofย Rapamycinย complex 1 (mTORC1) signaling
  3595. Dramatic improvement of facial angiofibromas in tuberous sclerosis with topicalย Rapamycin: optimizing a treatment protocol
  3596. Mapping the spatio-temporal pattern of the mammalian target ofย Rapamycinย (mTOR) activation in temporal lobe epilepsy
  3597. Rapamycinย inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression
  3598. Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target ofย Rapamycinย complex 1 activity
  3599. Rapamycinย exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependentย inhibitionย of Tor
  3600. Mammalian target ofย Rapamycinย complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons
  3601. Mammalian target ofย Rapamycinย complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1
  3602. Proteomic identification of novel targets regulated by the mammalian target ofย Rapamycinย pathway during oligodendrocyte differentiation
  3603. Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target ofย Rapamycinย complex 1 (mTORC1)
  3604. The influence of co-solvents on the stability and bioavailability ofย Rapamycinย formulated in self-microemulsifying drug delivery systems
  3605. Altered APP processing in insulin-resistant conditions is mediated by autophagosome accumulation via theย inhibitionย of mammalian target ofย Rapamycinย pathway
  3606. Rapamycinย has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption ofย mTORC1 andย mTORC2
  3607. Rapamycinย attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy
  3608. inhibitionย ofย mTORย byย Rapamycinย in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory
  3609. Convergence of the mammalian target ofย Rapamycinย complex 1-and glycogen synthase kinase 3-ฮฒโ€“signaling pathways regulates the innate inflammatory response
  3610. Rapamycinย for Treatment of Epilepsy: Antiseizure, Antiepileptogenic, Both, or Neither?ย Rapamycinย for Treatment of Epilepsy
  3611. Rapamycinย reduces clinical signs and neuropathic pain in a chronic model of experimental autoimmune encephalomyelitis
  3612. Stimulation of autophagy byย Rapamycinย protects neurons from remote degeneration after acute focal brain damage
  3613. The physiology and pathophysiology ofย Rapamycinย resistance: implications for cancer
  3614. Combination therapy targeting Akt and mammalian target ofย Rapamycinย improves functional outcome after controlled cortical impact in mice
  3615. Rapamycinย paradox resolved
  3616. Combiningย mTORย inhibitors withย Rapamycin-resistant T cells: a two-pronged approach to tumor elimination
  3617. Circadian regulation of mammalian target ofย Rapamycinย signaling in the mouse suprachiasmatic nucleus
  3618. Mammalian Target ofย Rapamycinย (mTOR) Inhibitors
  3619. Dietary restriction but notย Rapamycinย extends disease onset and survival of the H46R/H48Q mouse model of ALS
  3620. Rapamycinย with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study
  3621. Rapamycinย reduces reactive oxygen species in cultured human corneal endothelial cells
  3622. mTOR-dependent regulation of PHLPP expression controls theย Rapamycinย sensitivity in cancer cells
  3623. Mammalian target ofย Rapamycinย integrates diverse inputs to guide the outcome of antigen recognition in T cells
  3624. Targeting the mammalian target ofย Rapamycinย (mTOR) in cancer therapy: lessons from past and future perspectives
  3625. โ€ฆ mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target ofย Rapamycinย โ€ฆ
  3626. Consolidation and reconsolidation of contextual fear memory requires mammalian target ofย Rapamycin-dependent translation in the dorsal hippocampus
  3627. Effects of cyclosporine, tacrolimus andย Rapamycinย on renal calcium transport and vitamin D metabolism
  3628. AMP-dependent kinase/mammalian target ofย Rapamycinย complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications
  3629. Ghrelin contributes to derangements of glucose metabolism induced byย Rapamycinย in mice
  3630. TORC1 of fission yeast isย Rapamycinโ€sensitive
  3631. Target-of-Rapamycinย complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation
  3632. Therapy of sclerodermatous chronic graft-versus-host disease with mammalian target ofย Rapamycinย inhibitors
  3633. The tuberous sclerosis complexโ€“mammalian target ofย Rapamycinย pathway maintains the quiescence and survival of naive T cells
  3634. Low doseย Rapamycinย exacerbates autoimmune experimental uveitis
  3635. Rapamycinย impairs proliferation of transplanted islet ฮฒ cells
  3636. The role of mammalian target ofย Rapamycinย (mTOR) in the regulation of pancreatic ฮฒ-cell mass: implications in the development of type-2 diabetes
  3637. Observations on enhanced port wine stain blanching induced by combined pulsed dye laser andย Rapamycinย administration
  3638. Kinome-wide selectivity profiling of ATP-competitive mammalian target ofย Rapamycinย (mTOR) inhibitors and characterization of their binding kinetics
  3639. Adiponectin induces vascular smooth muscle cell differentiation via repression of mammalian target ofย Rapamycinย complex 1 and FoxO4
  3640. Activation of PI3K/AKT and MAPK pathway through a PDGFRฮฒ-dependent feedback loop is involved inย Rapamycinย resistance in hepatocellular carcinoma
  3641. Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target ofย Rapamycinย (mTOR) pathways
  3642. Redox regulates mammalian target ofย Rapamycinย complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway
  3643. Campylobacter jejuni induces colitis through activation of mammalian target ofย Rapamycinย signaling
  3644. Mechanistic target ofย Rapamycinย inhibitors in solid organ transplantation: from benchside to clinical use
  3645. Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target ofย Rapamycinย โ€ฆ
  3646. Differing effects ofย Rapamycinย andย mTORย kinase inhibitors on protein synthesis
  3647. Coupling nutrient sensing to metabolic homoeostasis: the role of the mammalian target ofย Rapamycinย complex 1 pathway
  3648. Impairment of object recognition memory byย Rapamycinย inhibitionย ofย mTORย in the amygdala or hippocampus around the time of learning or reactivation
  3649. Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target ofย Rapamycinย (mTOR) kinase inhibitor (GDC-0980) โ€ฆ
  3650. Phosphatidic acid activates mammalian target ofย Rapamycinย complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an โ€ฆ
  3651. A topical combination ofย Rapamycinย and tacrolimus for the treatment of angiofibroma due to tuberous sclerosis complex (TSC): a pilot study of nine Japanese patients โ€ฆ
  3652. Assessing the effectiveness ofย Rapamycinย on angiomyolipoma in tuberous sclerosis: a two years trial
  3653. Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 viaย inhibitionย of mammalian target ofย Rapamycin
  3654. Rapamycinย partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer
  3655. PDGF receptor alpha is an alternative mediator ofย Rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma
  3656. The emerging role of mammalian target ofย Rapamycinย inhibitors in the treatment of sarcomas
  3657. Differential effects ofย Rapamycinย on rods and cones during light-induced stress in albino mice
  3658. Evaluation ofย Rapamycin-induced cell death
  3659. Rapid cytoplasmic turnover of yeast ribosomes in response toย Rapamycinย inhibitionย of TOR
  3660. โ€ฆ mammalian target ofย Rapamycinย (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target ofย Rapamycinย โ€ฆ
  3661. Rapamycinย attenuates the expression of cocaineโ€induced place preference and behavioral sensitization
  3662. The mammalian target ofย Rapamycinย inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study
  3663. L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target ofย Rapamycin
  3664. Starvation andย Rapamycinย differentially regulate host cell lysosome exocytosis and invasion by Trypanosoma cruzi metacyclic forms
  3665. Paradoxical effects ofย Rapamycinย on experimental house dust mite-induced asthma
  3666. Magnetic nanoparticles andย Rapamycinย encapsulated into polymeric nanocarriers
  3667. Rapamycinย inhibits osteolysis and improves survival in a model of experimental bone metastases
  3668. Rapamycinย synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73
  3669. Rapamycinย inhibits transforming growth factor ฮฒโ€induced peritoneal angiogenesis by blocking the secondary hypoxic response
  3670. Calorie restriction andย Rapamycinย inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity
  3671. Facial angiofibromas treated with topicalย Rapamycin: an excellent choice with fast response
  3672. Rapamycinย blocks hepatoblastoma growth in vitro and in vivo implicating new treatment options in high-risk patients
  3673. Regulatory T cells require mammalian target ofย Rapamycinย signaling to maintain both homeostasis and alloantigen-driven proliferation in lymphocyte-replete mice
  3674. Spinal cord NMDA receptor-mediated activation of mammalian target ofย Rapamycinย is required for the development and maintenance of bone cancer-induced pain โ€ฆ
  3675. SIRT1 is required for the effects ofย Rapamycinย on high glucose-inducing mesangial cells senescence
  3676. The Akt/mammalian target ofย Rapamycinย pathway is activated and associated with adverse prognosis in soft tissue leiomyosarcomas
  3677. inhibitionย ofย Rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation
  3678. Emerging roles for mammalian target ofย Rapamycinย inhibitors in the treatment of solid tumors and hematological malignancies
  3679. An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target ofย Rapamycinย pathway and deregulation of local dendritic translation in a mouse โ€ฆ
  3680. Novel synergistic antitumor effects ofย Rapamycinย with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model
  3681. Mammalian target ofย Rapamycinย regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells
  3682. The mechanism ofย mTORย (mammalian target ofย Rapamycin) in a mouse model of polycystic ovary syndrome (PCOS)
  3683. Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target ofย Rapamycinย (mTOR) dual inhibitors
  3684. Mammalian target ofย Rapamycinย signaling in the podocyte
  3685. Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target ofย Rapamycin
  3686. Mao-B elevation decreases parkinโ€™s ability to efficiently clear damaged mitochondria: protective effects ofย Rapamycin
  3687. Immunoregulatory properties ofย Rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation
  3688. Novel feedbackย inhibitionย of surface antigen synthesis by mammalian target ofย Rapamycinย (mTOR) signal and its implication for hepatitis B virus tumorigenesis and โ€ฆ
  3689. A Hexane Fraction of Guava Leaves (Psidium guajava L.) Induces Anticancer Activity by Suppressing AKT/Mammalian Target ofย Rapamycin/Ribosomal p70 S6 โ€ฆ
  3690. Clinical activity of mammalian target ofย Rapamycinย inhibitors in solid tumors
  3691. A novel application of topicalย Rapamycinย formulation, an inhibitor ofย mTOR, for patients with hypomelanotic macules in tuberous sclerosis complex
  3692. Targeting notch pathway enhancesย Rapamycinย antitumor activity in pancreas cancers through PTEN phosphorylation
  3693. Rapamycinย ameliorates dystrophic phenotype in mdx mouse skeletal muscle
  3694. Mammalian target ofย Rapamycinย expression in poorly differentiated endocrine carcinoma: clinical and therapeutic future challenges
  3695. Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target ofย Rapamycinย inhibitors
  3696. Grape polyphenols inhibit Akt/mammalian target ofย Rapamycinย signaling and potentiate the effects of gefitinib in breast cancer
  3697. Rapamycinย increases the yield and effector function of human ฮณฮด T cells stimulated in vitro
  3698. Rapamycinย combined with TGF-ฮฒ converts human invariant NKT cells into suppressive Foxp3+ regulatory cells
  3699. Effect of dietary choline on growth, intestinal enzyme activities and relative expressions of target ofย Rapamycinย and eIF4E-binding protein2 gene in muscle โ€ฆ
  3700. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target ofย Rapamycinย (mTOR)-dependentย inhibitionย of โ€ฆ
  3701. Role of mammalian target ofย Rapamycinย in hypoxic or ischemic brain injury: potential neuroprotection and limitations
  3702. Spinal phosphinositide 3-Kinaseโ€“Aktโ€“Mammalian target ofย Rapamycinย signaling cascades in inflammation-induced hyperalgesia
  3703. Enteric-deliveredย Rapamycinย enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence
  3704. Mechanistic or mammalian target ofย Rapamycinย (mTOR) may determine robustness in young male mice at the cost of accelerated aging
  3705. Intermittent supplementation withย Rapamycinย as a dietary restriction mimetic
  3706. Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target ofย Rapamycinย interaction proteome
  3707. The histone H3 lysine 56 acetylation pathway is regulated by target ofย Rapamycinย (TOR) signaling and functions directly in ribosomal RNA biogenesis
  3708. TOR: target ofย Rapamycin
  3709. Ksp1 kinase regulates autophagy via the target ofย Rapamycinย complex 1 (TORC1) pathway
  3710. Multiple site acetylation of Rictor stimulates mammalian target ofย Rapamycinย complex 2 (mTORC2)-dependent phosphorylation of Akt protein
  3711. Clinical outcomes in kidney transplant recipients receiving longโ€term therapy with inhibitors of the mammalian target ofย Rapamycin
  3712. Rapamycinย preconditioning attenuates transient focal cerebral ischemia/reperfusion injury in mice
  3713. โ€ฆ of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target ofย Rapamycinย complex 1 (mTORC1) โ€ฆ
  3714. Mammalian target ofย Rapamycinย and head and neck squamous cell carcinoma
  3715. Rapamycin-insensitiveย mTORC1 activity controls eIF4E: 4E-BP1 binding
  3716. Mammalian target ofย Rapamycinย is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/ฮฒ-catenin and PTEN
  3717. Rapamycinย suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy
  3718. Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target ofย Rapamycinย signaling network in cancer stem cells
  3719. Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target ofย Rapamycinย (AMPK/mTOR) and c-Jun N-terminal kinase โ€ฆ
  3720. Mechanistic mammalian target ofย Rapamycinย (mTOR) cell signaling: effects of select nutrients and secreted phosphoprotein 1 on development of mammalian โ€ฆ
  3721. Theย mTORย (mammalian target ofย Rapamycin) kinase maintains integrity ofย mTORย complex 2
  3722. Rapamycin-mediatedย mTORย inhibitionย attenuates survivin and sensitizes glioblastoma cells to radiation therapy
  3723. Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of aย Rapamycinย analogue library
  3724. Rapamycinย has paradoxical effects on S6 phosphorylation in rats with and without seizures
  3725. A retrospective review of oral low-dose sirolimus (Rapamycin) for the treatment of active uveitis
  3726. Elimination of proliferating cells unmasks the shift from senescence to quiescence caused byย Rapamycin
  3727. Drosophila insulin and target ofย Rapamycinย (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo
  3728. Rapamycinย treatment inhibits CHO cell death in a serumโ€free suspension culture by autophagy induction
  3729. Mammalian target ofย Rapamycinย (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing
  3730. Rapamycinย Reverses Splenomegaly and Inhibits Tumor Development in a Transgenic Model of Epstein-Barr Virusโ€“Related Burkittโ€™s Lymphoma
  3731. A combined approach of classical mutagenesis and rational metabolic engineering improvesย Rapamycinย biosynthesis and provides insights into methylmalonyl-CoA โ€ฆ
  3732. The risk of skin rash and stomatitis with the mammalian target ofย Rapamycinย inhibitor temsirolimus: a systematic review of the literature and meta-analysis
  3733. Rapamycinย reduces oxidative stress in frataxin-deficient yeast cells
  3734. Advantage ofย Rapamycinย over mycophenolate mofetil when used with tacrolimus for simultaneous pancreas kidney transplants: randomized, singleโ€center trial at 10 โ€ฆ
  3735. Phosphorylation of Raptor by p38ฮฒ participates in arsenite-induced mammalian target ofย Rapamycinย complex 1 (mTORC1) activation
  3736. Synergistic activity ofย Rapamycinย and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis
  3737. โ€ฆ and a signaling core formed by bifunctional Akt, extracellular signal-regulated kinase (ERK) 1/2, and mammalian target ofย Rapamycinย complex 1 (mTORC1) โ€ฆ
  3738. LST8 regulates cell growth via target-of-Rapamycinย complex 2 (TORC2)
  3739. The mammalian target ofย Rapamycinย pathway is widely activated without PTEN deletion in renal cell carcinoma metastases
  3740. Rapamycinย induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells
  3741. Evaluation of sphingolipid metabolism in renal cortex of rats with streptozotocin-induced diabetes and the effects ofย Rapamycin
  3742. Dissecting mammalian target ofย Rapamycinย to promote longevity
  3743. Rapamycinย treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium
  3744. Impact ofย Rapamycinย on peritoneal fibrosis and transport function
  3745. Predictive biomarkers for the activity of mammalian target ofย Rapamycinย (mTOR) inhibitors
  3746. Rapamycinโ€Induced Hypophosphatemia and Insulin Resistance Are Associated Withย mTORC2 Activation and Klotho Expression
  3747. Phospshoinositide 3-kinase (PI3K)/mammalian target ofย Rapamycinย (mTOR) dual inhibitors: discovery and structureโ€“activity relationships of a series of quinoline and โ€ฆ
  3748. Emergence of the phosphoinositide 3-kinase-Akt-mammalian target ofย Rapamycinย axis in transforming growth factor-ฮฒ-induced epithelial-mesenchymal transition
  3749. Activation of mammalian target ofย Rapamycinย pathway confers adverse outcome in nonsmall cell lung carcinoma
  3750. Dualย inhibitionย of phosphatidylinositol 3โ€kinase/Akt and mammalian target ofย Rapamycinย signaling in human nonsmall cell lung cancer cells by a dietary flavonoid โ€ฆ
  3751. S6 kinase 1 is required forย Rapamycin-sensitive liver proliferation after mouse hepatectomy
  3752. Metabolic regulation, mitochondria and the life-prolonging effect ofย Rapamycin: a mini-review
  3753. Induction of melanogenesis byย Rapamycinย in human MNT-1 melanoma cells
  3754. Calcineurin inhibitor sparing regimens using mโ€target ofย Rapamycinย inhibitors: an opportunity to improve cardiovascular risk following kidney transplantation?
  3755. The mammalian target ofย Rapamycinย pathway as a therapeutic target in multiple myeloma
  3756. โ€ฆ and its associated cell death by โ€œsphingolipid rheostatโ€: reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target ofย Rapamycinย โ€ฆ
  3757. Rapamycinย sensitiveย mTORย activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment โ€ฆ
  3758. Regulation of the glutamate transporter EAAT3 by mammalian target ofย Rapamycinย mTOR
  3759. Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target ofย Rapamycinย (mTOR)
  3760. The mammalian target ofย Rapamycinย inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in โ€ฆ
  3761. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target ofย Rapamycinย Complex โ€ฆ
  3762. NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitors, enhance tumor and endothelial cell โ€ฆ
  3763. An elaborate regulation of Mammalian target ofย Rapamycinย activity is required for somatic cell reprogramming induced by defined transcription factors
  3764. Rapamycin-induced posterior reversible encephalopathy in a kidney transplantation patient
  3765. Mammalian target ofย Rapamycinย pathway activation is associated to RET mutation status in medullary thyroid carcinoma
  3766. โ€ฆ secretion via down-regulation of surface expression of adrenergic ฮฑ2A receptor through theย mTORย (mammalian target ofย Rapamycin) pathway: implication in โ€ฆ
  3767. Rapamycinย enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation
  3768. Beta cell function duringย Rapamycinย monotherapy in long-term type 1 diabetes
  3769. Temporal regulation ofย Rapamycinย on memory CTL programming by IL-12
  3770. Rapamycinย prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and-9: an in vitro study
  3771. TGFฮฒโ€and bleomycinโ€induced extracellular matrix synthesis is mediated through Akt and mammalian target ofย Rapamycinย (mTOR)
  3772. cAMP inhibits mammalian target ofย Rapamycinย complex-1 and-2 (mTORC1 and 2) by promoting complex dissociation and inhibitingย mTORย kinase activity
  3773. Enhanced delivery ofย Rapamycinย by V156K-apoA-I high-density lipoprotein inhibits cellular proatherogenic effects and senescence and promotes tissue regeneration
  3774. Interpreting mammalian target ofย Rapamycinย and cell growthย inhibitionย in a genetically engineered mouse model of Nf1-deficient astrocytes
  3775. First report of a novel abluminal groove filled biodegradable polymerย Rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK โ€ฆ
  3776. Autophagy induced byย Rapamycinย and carbonโ€starvation have distinct proteome profiles in Aspergillus nidulans
  3777. An emerging role for the mammalian target ofย Rapamycinย in โ€œpathologicalโ€ protein translation: relevance to cocaine addiction
  3778. Rapamycin-cyclodextrin complexation: improved solubility and dissolution rate
  3779. inhibitionย of autophagy as a strategy to augment radiosensitization by the dual phosphatidylinositol 3-kinase/mammalian target ofย Rapamycinย inhibitor NVP-BEZ235
  3780. Regulation of mammalian target ofย Rapamycinย and mitogen activated protein kinase pathways by BCRโ€“ABL
  3781. mTORย in podocyte function: isย Rapamycinย good for diabetic nephropathy?
  3782. Yin Yang 1 deficiency in skeletal muscle protects againstย Rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling
  3783. ULK1, mammalian target ofย Rapamycin, and mitochondria: linking nutrient availability and autophagy
  3784. Mammalian target ofย Rapamycinย mediates the angiogenic effects of leptin in human hepatic stellate cells
  3785. Forced degradation studies ofย Rapamycin: Identification of autoxidation products
  3786. Inactivation of mammalian target ofย Rapamycinย (mTOR) byย Rapamycinย in a murine model of lipopolysaccharide-induced acute lung injury
  3787. Pharmacological targeting of mammalian target ofย Rapamycinย inhibits ovarian granulosa cell tumor growth
  3788. Innovations therapy: mammalian target ofย Rapamycinย (mTOR) inhibitors for the treatment of neuroendocrine tumors
  3789. Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited byย Rapamycinย and the other by โ€ฆ
  3790. Myopathy caused by mammalian target ofย Rapamycinย complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function
  3791. Remarkableย inhibitionย ofย mTORย signaling by the combination ofย Rapamycinย and 1, 4โ€phenylenebis (methylene) selenocyanate in human prostate cancer cells
  3792. Regulatory T cells expanded byย Rapamycinย in vitro suppress colitis in an experimental mouse model
  3793. Combination of an allosteric Akt Inhibitor MK-2206 with etoposide orย Rapamycinย enhances the antitumor growth effect in neuroblastoma
  3794. Localized ultrasound enhances delivery ofย Rapamycinย from microbubbles to prevent smooth muscle proliferation
  3795. inhibitionย of Akt (ser473) phosphorylation andย Rapamycin-resistant cell growth by knockdown of mammalian target ofย Rapamycinย with small interfering RNA in vascular โ€ฆ
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