Nmda & Anxiety & Depression

โ€“ Hippocampal NMDA receptors play a central role in emotionality and cognition, impacting fear, anxiety, and depression. โ€“ NMDA receptor antagonists affect anxiety and depression by targeting NMDA receptors in the hippocampus, especially the ventral part. โ€“ The ventral hippocampus is crucial for anxiolytic effects and is linked to emotional processing areas like the prefrontal cortex and amygdala. โ€“ Studies show that hippocampal lesions, particularly in the ventral hippocampus, reduce anxiety. โ€“ The hippocampus, traditionally known for memory, is implicated in anxiety and depression, with the ventral region being particularly relevant. โ€“ Genetically modified mice lacking specific NMDA receptor subunits in the hippocampus exhibit reduced anxiety, supporting the role of hippocampal NMDA receptors in anxiety regulation. โ€“ Cellular mechanisms underlying anxiety and depression, emphasizing the importance of further studies with genetically modified mice to uncover these mechanisms. โ€“ Interactions between NMDA receptors and other neurotransmitter systems, such as glycine-B receptors, serotonin receptors, and GABA(A) receptors, also play a role in modulating anxiety and depression. โ€“ Various behavioral tests, including the elevated plus maze and conditioned fear conditioning paradigms, have been used to assess the effects of NMDA receptor modulation on anxiety and depression-related behaviors.

  1. A Calcineurin/Akap Complex Is Required ForNmdaย Receptorโ€“Dependent Long-Term Depression
  2. A Computational Study On The Role Of Glutamate AndNmdaย Receptors On Cortical Spreadingdepressionย Using A Multidomain Electrodiffusion Model
  3. A High-Dose Of Fentanyl Induced Delayed Anxiety-Like Behavior In Rats. Prevention By ANmdaย Receptor Antagonist And Nitrous Oxide (N2O)
  4. A Neurotrophic Hypothesis Of Depression: Role Of Synaptogenesis In The Actions OfNmdaย Receptor Antagonists
  5. A Translational Approach ForNmdaย Receptor Profiling As A Vulnerability Biomarker Fordepressionย And Schizophrenia
  6. AberrantNmdaย Receptor Dna Methylation Detected By Epigenome-Wide Analysis Of Hippocampus And Prefrontal Cortex In Major Depression
  7. Abnormal Striatal Expression Of Transcripts EncodingNmdaย Interacting Psd Proteins In Schizophrenia, Bipolar Disorder And Major Depression
  8. Acetylcysteine Against Alcohol Abstinence-Induceddepressionย By Regulating Biochemical And Grin2A, Grin2B Gene Expression OfNmdaย Receptor Signaling Pathway โ€ฆ
  9. Activation OfNmdaย Receptors Reduces Metabotropic Glutamate Receptor-Induced Long-Termdepressionย In The Nucleus Accumbens Via A Camkii-Dependent Mechanism
  10. Activation Of Nr2B-ContainingNmdaย Receptors Is Not Required ForNmdaย Receptor-Dependent Long-Term Depression
  11. Adaptation Of N-Methyl-D-Aspartate (Nmda) Receptors Following Antidepressant Treatment: Implications For The Pharmacotherapy Of Depression
  12. Age Dependence Of Homosynaptic Non-Nmdaย Mediated Long-Termdepressionย In Field Ca1 Of Rat Hippocampal Slices
  13. Alleviation Of Cognitive Deficits And High Copper Levels By AnNmdaย Receptor Antagonist In A Ratdepressionย Model
  14. Alterations InNmdaย Receptor Subunit Densities And Ligand Binding To Glycine Recognition Sites Are Associated With Chronicanxietyย In Alzheimerโ€™S Disease
  15. Ameliorating Treatment-Refractorydepressionย With Intranasal Ketamine: PotentialNmdaย Receptor Actions In The Pain Circuitry Representing Mental Anguish
  16. Ampa AndNmdaย Currents Show Different Shortโ€Termdepressionย In The Dorsal Lateral Geniculate Nucleus Of The Rat
  17. An Investigation Of Two Animal Models Of Anxiety: Central Administration Of Corticotropin-Releasing Factor On The Behaviour And Neurochemistry Of Rats, And The โ€ฆ
  18. An Nmda-Receptor Antagonist, Mk-801 Blocks The Suppressive Vasopressin Response To Fear-But Not To Anxiety-Related Stimuli In The Rat.
  19. An Update OnNmdaย Antagonists In Depression
  20. Anandamide, Cannabinoid Type 1 Receptor, AndNmdaย Receptor Activation Mediate Non-Hebbian Presynaptically Expressed Long-Termdepressionย At The First Central โ€ฆ
  21. And Sertraline Treatments Alone And In Combination On The Binding Properties Of CorticalNmdaย And ฮ’1-Adrenergic Receptors In An Animal Model Of Depression
  22. Antidepressant Activity Of Non-Competitive And CompetitiveNmdaย Receptor Antagonists In A Chronic Mild Stress Model Of Depression
  23. Antidepressant Effect Of Ketamine, A N-Methyl-D-Aspartate (Nmda) Glutamate Receptor Antagonist, In The Therapy Of Treatment-Resistant Depression
  24. Anxiety-Behavior Modulated By Ventral Medial Prefrontal Cortex Of Rats Submitted To The Vogel Conflict Test Involves A LocalNmdaย Receptor And Nitric Oxide
  25. Anxiety-Like Responses Induced By Nitric Oxide Within The Bnst In Mice: Role Of Crf1 AndNmdaย Receptors
  26. Astrocytic P38ฮ‘ Mapk DrivesNmdaย Receptor-Dependent Long-Termdepressionย And Modulates Long-Term Memory
  27. Autismโ€Associated Shank3 Mutations Alter Mglur Expression And Mglurโ€Dependent But NotNmdaย Receptorโ€Dependent Longโ€Term Depression
  28. Behavioural Effects Of Acute And Chronic Memantine Administration In Rats: Further Support ForNmdaย As A New Pharmacological Target For The Treatment Of Depression?
  29. Blockade OfNmdaย Receptors Unmasks A Long-Termdepressionย In Synaptic Efficacy In Rat Prefrontal Neurons In Vitro
  30. BlockingNmdaย Receptor At Rest: A Possible Alleviation Of Depression
  31. Bnst Glun2D-ContainingNmdaย Receptors Influence Anxiety-And Depressive-Like Behaviors And Modulatecell-Specific Excitatory/Inhibitory Synaptic Balance
  32. Both Nr2A And Nr2B Subunits Of TheNmdaย Receptor Are Critical For Long-Term Potentiation And Long-Termdepressionย In The Lateral Amygdala Of Horizontal Slices Of โ€ฆ
  33. BrainNmdaย Receptors In Schizophrenia And Depression
  34. Bridging The Gap Between The Immune And Glutamate Hypotheses Of Schizophrenia And Major Depression: Potential Role Of GlialNmdaย Receptor Modulators And โ€ฆ
  35. Calcineurin Plays Different Roles In Group Ii Metabotropic Glutamate Receptor-AndNmdaย Receptor-Dependent Long-Term Depression
  36. Calcium Antagonists In The Olfactory Bulbectomy Animal Model Of Depression: Effect On The CorticalNmdaย Receptor Complex.
  37. Characterization OfNmdaย Induceddepressionย In Rat Hippocampus: Involvement Of Ampa AndNmdaย Receptors
  38. Cofilin Under Control Of ฮ’-Arrestin-2 In Nmda-Dependent Dendritic Spine Plasticity, Long-Termdepressionย (Ltd), And Learning
  39. Cognitive And Emotional Empathy After Stimulation Of Brain Mineralocorticoid AndNmdaย Receptors In Patients With Majordepressionย And Healthy Controls
  40. Combined Use Of Behavioral Therapy And PartialNmdaย Agonist To Treatanxietyย Disorders
  41. Commentary: TargetingNmdaย Receptor And Serotonin Transporter For The Treatment Of Comorbid Alcohol Dependence And Depression
  42. Conditioning Of The Gill-Withdrawal Reflex In Aplysia Recruits BothNmdaย Receptor-Dependent Enhancement AndNmdaย Receptor-Dependentdepressionย Of The Reflex
  43. Cp-101,606, An Nr2B Subunit SelectiveNmdaย Receptor Antagonist, InhibitsNmdaย And Injury Induced C-Fos Expression And Cortical Spreadingdepressionย In Rodents
  44. Cpp, A New Potent And SelectiveNmdaย Antagonist.depressionย Of Central Neuron Responses, Affinity For [3H] D-Ap5 Binding Sites On Brain Membranes And โ€ฆ
  45. Cpp, An Nmda-Receptor Antagonist, Blocks 4-Aminopyridine-Induced Spreadingdepressionย Episodes But Not Epileptiform Activity In Immature Rat Hippocampal Slices
  46. Critical Differences In Magnitude And Duration Of N-Methyl-D-Aspartate (Nmda) Receptor Activation Between Long-Term Potentiation (Ltp) And Long-Termdepressionย โ€ฆ
  47. D-2-Amino-5-Phosphonovaleate Blocks Induction Of Long-Termdepressionย Of TheNmdaย Receptor-Mediated Synaptic Component In Rat Hippocampus
  48. Dcf1 Affects Memory Andanxietyย By RegulatingNmdaย And Ampa Receptors
  49. depressionย Of Extra-Cellular Gaba And Increase Of Nmda-Induced Nitric Oxide Following Acute Intra-Nuclear Administration Of Alcohol In The Cerebellar Nuclei Of The Rat
  50. depressionย OfNmdaย Receptorโ€Mediated Synaptic Transmission By Four ฮ‘2 Adrenoceptor Agonists On The In Vitro Rat Spinal Cord Preparation
  51. depressionย Of Nmda-Evoked Acetylcholine Release By Endogenous Adenosine In Striatum Slices
  52. depressionย Of Nmda-Receptor-Mediated Segmental Transmission By Ketamine And Ketoprofen, But Not L-Name, On The In Vitro Neonatal Rat Spinal Cord Preparation
  53. depressionย Of Purine Induced Inhibition DuringNmdaย Receptor Mediated Activation Of Hippocampal Pyramidal Cellsโ€”An Iontophoretic Study
  54. depressionย Of Synaptic Transmission And EvokedNmdaย Ca2+ Influx In Hippocampal Neurons By Adenosine And Its Blockade By Ltp Or Ischemia
  55. Developmental Alterations Of Dhpg-Induced Long-Termdepressionย Of Corticostriatal Synaptic Transmission: Switch FromNmdaย Receptor-Dependent Towards Cb1 โ€ฆ
  56. Developmentaldepressionย Of Glutamate Neurotransmission By Chronic Low-Level Activation OfNmdaย Receptors
  57. Developmental Switch In The Contribution Of Presynaptic And PostsynapticNmdaย Receptors To Long-Term Depression
  58. Dexras1 A Unique Ras-Gtpase Interacts WithNmdaย Receptor Activity And Provides A Novel Dissociation Between Anxiety, Working Memory And Sensory Gating
  59. Differential Paired Pulsedepressionย Of Non-Nmdaย AndNmdaย Currents In Pyramidal Cells Of The Rat Frontal Cortex
  60. Differential Roles Of Nr2A And Nr2B-ContainingNmdaย Receptors In Cortical Long-Term Potentiation And Long-Term Depression
  61. Disruption Of TheNmdaย Receptor Glun2A Subunit Abolishes Inflammation-Induced Depression
  62. DistinctNmdaย Receptor Subpopulations Contribute To Long-Term Potentiation And Long-Termdepressionย Induction
  63. Dopamine D1 AndNmdaย Receptors Interaction In The Dorsal Hippocampus Of Rats In The Elevated Plus Maze Test Of Anxiety
  64. Dopamine D1/D5 Receptor Activation ReversesNmdaย Receptor-Dependent Long-Termdepressionย In Rat Hippocampus
  65. Dopamine Induces A Glun2A-Dependent Form Of Long-Termdepressionย OfNmdaย Synaptic Responses In The Nucleus Accumbens
  66. Double Dissociation Of Spike Timingโ€“Dependent Potentiation Anddepressionย By Subunit-PreferringNmdaย Receptor Antagonists In Mouse Barrel Cortex
  67. Downregulation Of Mglur2/3 Receptors During Morphine Withdrawal In Rats Impairs Mglur2/3-AndNmdaย Receptor-Dependent Long-Termdepressionย In The Nucleus โ€ฆ
  68. D-Serine As The Gatekeeper OfNmdaย Receptor Activity: Implications For The Pharmacologic Management Ofanxietyย Disorders
  69. D-Serine Augments Nmda-Nr2B Receptor-Dependent Hippocampal Long-Termdepressionย And Spatial Reversal Learning
  70. Dysregulated Nmda-Receptor Signaling Inhibits Long-Termdepressionย In A Mouse Model Of Fragile X Syndrome
  71. Effect Of Sigma Ligands OnNmdaย Receptor Function In The Bulbectomy Model Of Depression: A Behavioural Study In The Rat
  72. Effects Of Activation And Blockade OfNmdaย Receptors On The Extinction Of A Conditioned Passive Avoidance Response In Mice With Different Levels Of Anxiety
  73. Effects Of An Nmda-Receptor Antagonist, Mk-801 On Emotional Memory Associated With Neurohypophysial Responses To Fear Oranxietyย Stimuli In Rats
  74. Effects Of Antagonists At TheNmdaย Receptor Complex In Two Models Of Anxiety
  75. Effects Of Behavioraldepressionย And Chronic Influence Of Antidepressants On Nmda/Glutamate Receptor-Mediated Responses Of Neurons Of The Rat Gyrus Dentatus
  76. Effects Of Intraโ€Accumbens Blockade OfNmdaย Receptors In Two Models Of Anxiety, In Rats
  77. Effects Of Memantine OnNmdaย Induced Longโ€Termdepressionย In Mouse Models Of Down Syndrome
  78. Effects OfNmdaย Antagonists On Ethanol-Withdrawal Induced โ€œAnxietyโ€ In The Elevated Plus Maze
  79. Effects OfNmdaย Receptor Antagonists On Opioid-Induced Respiratorydepressionย And Acute Antinociception In Rats
  80. Effects OfNmdaย Receptor Antagonists With Different Subtype Selectivities On Retinal Spreading Depression
  81. Effects Of Respiratorydepressionย On Cytoprotective Effect Of The CompetitiveNmdaย Antagonist, D-Cppene
  82. Effects Of Sigma Ligands OnNmdaย Receptor Function In The Bulbectomy Model Of Depression: A Behavioural Study In The Rat
  83. Effects Of Site-SelectiveNmdaย Receptor Antagonists In An Elevated Plus-Maze Model Ofanxietyย In Mice
  84. Effects Of Venlafaxine And Escitalopram Treatments OnNmdaย Receptors In The Ratdepressionย Model
  85. Elevated Levels Of The Nr2C Subunit Of TheNmdaย Receptor In The Locus Coeruleus In Depression
  86. Elevated T-Maze Evaluation Ofanxietyย And Memory Effects Of Nmda/Glycine-B Site Ligands Injected Into The Dorsal Periaqueductal Gray Matter And The Superior โ€ฆ
  87. Embryonic Ketamine Produces A Downregulation Of Prefrontal CortexNmdaย Receptors And Anxiety-Like Behavior In Adult Offspring
  88. Endogenous Ph Shifts Facilitate Spreadingdepressionย By Effect OnNmdaย Receptors
  89. Enhancement Of Paired-Pulsedepressionย In The Dentate Gyrus In Vivo By TheNmdaย Antagonist, Mk-801, And Electrical Kindling
  90. Ephb2 Deficiency Induces Depression-Like Behaviors And Memory Impairment: Involvement OfNmdaย 2B Receptor Dependent Signaling
  91. Ethanol Modulation OfNmdaย Receptors And Nmdar-Dependent Long-Termdepressionย In The Developing Juvenile Dentate Gyrus
  92. Evidence For A Role Of The N-Methyl-D-Aspartate (Nmda) Receptor In Cortical Spreadingdepressionย In The Rat
  93. Exhaust Particles Causes Anxiety, Spatial Memory Disorders With Alters Expression Of Hippocampal Pro-Inflammatory Cytokines AndNmdaย Receptor Subunits In โ€ฆ
  94. Experimental Cortical Spreadingdepressionย InducesNmdaย Receptor Dependent Potassium Currents In Microglia
  95. Expression Of PostsynapticNmdaย And Ampa Receptor Subunits In The Hippocampus And Prefrontal Cortex Of The Flinders Sensitive Line Rat Model Of Depression
  96. Facilitation Of AnNmdaย Receptorโ€Mediated Epsp By Pairedโ€Pulse Stimulation In Rat Neocortex Viadepressionย Of Gabaergic Ipsps.
  97. Fast Nongenomic Neuroprotection Mediated By Gpr30-Dependentdepressionย Of Nr2B-ContainingNmdaย Receptors
  98. ForebrainNmdaย Receptor 2B Subunit Over-Expression Has No Influence Onanxietyย Behaviors Of Mice.
  99. Gaba AndNmdaย Receptors In Crf Neurons Have Opposing Effects In Fear Acquisition Andanxietyย In Central Amygdala Vs. Bed Nucleus Of The Stria Terminalis
  100. Generation And Propagation Of Cortical Spreadingdepressionย Is Mediated By TheNmdaย Receptor
  101. Glucocorticoid Receptor Activation Lowers The Threshold For Nmda-Receptor-Dependent Homosynaptic Long-Termdepressionย In The Hippocampus Through Activation Of โ€ฆ
  102. Glun2B Subunits Of TheNmdaย Receptor Contribute To The Ampa Receptor Internalization During Long-Termdepressionย In The Lateral Amygdala Of Juvenile Rats
  103. Glun2B-ContainingNmdaย Receptors Regulate Depression-Like Behavior And Are Critical For The Rapid Antidepressant Actions Of Ketamine
  104. GlutamateNmdaย Receptor Modulators For The Treatment Of Depression: Trials And Tribulations
  105. GlutamatergicNmdaย Receptor As Therapeutic Target For Depression
  106. GlutamatergicNmdaย Receptors As Targets For The Therapy Of Depression
  107. G-Protein-Coupled Receptor 30 Mediates Rapid Neuroprotective Effects Of Estrogen Viadepressionย Of Nr2B-ContainingNmdaย Receptors
  108. Group Ii Mglur-Induced Long Termdepressionย In The Dentate Gyrus In Vivo IsNmdaย Receptor-Independent And Does Not Require Protein Synthesis
  109. HippocampalNmdaย Receptors And Anxiety: At The Interface Between Cognition And Emotion
  110. Ifenprodil And Ethanol EnhanceNmdaย Receptor-Dependent Long-Term Depression
  111. Il-1 Receptor Antagonist Improves Anxiety-Like Behavior Induced By Chronic Neuropathic Pain Via The Blockade Of PhosphorylationofNmdaย Receptors On Neurons โ€ฆ
  112. Improvement Of Symptoms In A Rat Model Ofdepressionย Through Combined Zinc And Folic Acid Administration Via Up-Regulation Of The Trk B And Nmda
  113. In Human Peripheral Blood Mononuclear Cells (Pbmcs) Where The Expression Of Gluk4 Is Altered By Pregnancy And Glun2D Bydepressionย In Pregnant Women
  114. Independent Mechanisms For Long-Termdepressionย Of Ampa AndNmdaย Responses
  115. Induction And Expression Mechanisms Of PostsynapticNmdaย Receptor-Independent Homosynaptic Long-Term Depression
  116. Induction OfNmdaย Receptor-Dependent Long-Termdepressionย In Visual Cortex Does Not Require Metabotropic Glutamate Receptors
  117. Influence Of Activation And Blockade OfNmdaย Receptors On Extinction Of Passive Avoidance Response In Mice With Different Levels Of Anxiety
  118. Insulin Sensitizer, Normalizes Behavior, Rem Sleep, Hippocampal Pgsk3 Beta And Mrnas OfNmdaย Receptor Subunits In Mouse Models Of Depression
  119. Interaction Between Dopamine D2 AndNmdaย Receptors In The Dorsal Hippocampus Of Rats In The Elevated Plus-Maze Test Of Anxiety
  120. InterneuronalNmdaย Receptors Regulate Longโ€Termdepressionย And Motor Learning In The Cerebellum
  121. InvestigationalNmdaย Receptor Modulators For Depression
  122. Involvement Of Crf But Not Npy In Theanxietyย Regulation ViaNmdaย Receptors
  123. Involvement Of Dorsal Hippocampal Nmda-Glutamatergic System In Anxiety-Related Behaviors Of Rats
  124. Involvement Of HippocampalNmdaย Receptor And Neuropeptide Y Indepressionย Induced By Chronic Unpredictable Mild Stress
  125. Involvement Of HippocampalNmdaย Receptor And Nitric Oxide Synthase Indepressionย Induced By Chronic Unpredicted Mild Stress
  126. Involvement OfNmdaย Receptor In Low-Frequency Magnetic Field-Inducedanxietyย In Mice
  127. Involvement OfNmdaย Receptor Subtypes In Cortical Spreadingdepressionย In Rats Assessed By Fmri
  128. Involvement Of Synaptic Nr2B-ContainingNmdaย Receptors In Long-Termdepressionย Induction In The Young Rat Visual Cortex In Vitro
  129. Involvement Of The Metabotropic Glutamate Receptor Mglur5 InNmdaย Receptor-Dependent, Learning-Facilitated Long-Termdepressionย In Ca1 Synapses
  130. IonotropicNmdaย Receptor Signaling Is Required For The Induction Of Long-Termdepressionย In The Mouse Hippocampal Ca1 Region
  131. Isoflurane-Induceddepressionย Of Synaptic Ltp Does Not Involve Post-Nmdaย Receptor Mediated Mechanisms
  132. Ketamine And OtherNmdaย Antagonists: Early Clinical Trials And Possible Mechanisms In Depression
  133. Ketamine And The Future OfNmdaย Antagonists In The Treatment Of Depression
  134. Lack Of Antidepresant-Like Activity Of Some Ligands Of Polyamine Binding Sites OfNmdaย Receptors In Models Of Depression
  135. Lasting Neurondepressionย Induced By High Potassium And Its Prevention By Low Calcium AndNmdaย Receptor Blockade
  136. Leptin Induces A Novel Form OfNmdaย Receptorโ€Dependent Longโ€Term Depression
  137. Longโ€Termdepressionย In The Hippocampal Ca1 Region Is Associated With Equal Changes In Ampa AndNmdaย Receptorโ€Mediated Synaptic Potentials
  138. Long-Termdepressionย In The Rat Hippocampus As A Memory Model: Interrogating The Role Of Protein Synthesis In Nmda-And Mglur-Dependent Synaptic Plasticity
  139. Long-Termdepressionย OfNmdaย Receptor-Mediated Synaptic Transmission Is Dependent On Activation Of Metabotropic Glutamate Receptors And Is Altered To Long-Term โ€ฆ
  140. Long-Termdepressionย OfNmdaย Receptor-Mediated Transmission In The Ca1 Region Of The Hippocampus
  141. Long-Termdepressionย Of Presynaptic Release From The Readily Releasable Vesicle Pool Induced ByNmdaย Receptor-Dependent Retrograde Nitric Oxide
  142. Long-Termdepressionย Requiring Tacpd-Receptor Activation And Nmda-Receptor Blockade
  143. Long-Term Depression-Associated Signaling Is Required For An In Vitro Model OfNmdaย Receptor-Dependent Synapse Pruning
  144. Long-Term Depression-Inducing Stimuli Promote Cleavage Of The Synaptic Adhesion Molecule Ngl-3 ThroughNmdaย Receptors, Matrix Metalloproteinases And โ€ฆ
  145. Long-Term Potentiation And Long-Termdepressionย Are Induced Through Pharmacologically DistinctNmdaย Receptors
  146. Loss Of Glun2B-ContainingNmdaย Receptors In Ca1 Hippocampus And Cortex Impairs Long-Term Depression, Reduces Dendritic Spine Density, And Disrupts Learning
  147. Low-Affinity Kainate Receptors And Long-Lastingdepressionย Of Nmda-Receptorโ€“Mediated Currents In Rat Superficial Dorsal Horn
  148. Measuring Dissociative Effects OfNmdaย Receptor Antagonists In The Treatment Of Depression
  149. Mechanisms Of Group I Mglur-Dependent Long-Termdepressionย OfNmdaย Receptorโ€“Mediated Transmission At Schaffer Collateralโ€“Ca1 Synapses
  150. Medial Prefrontal CorticalNmdaย Receptors Regulate Depression-Like Behavior And Dictate Limbic Thalamus Innervation
  151. Memory Improvement After Spreadingdepressionย ByNmdaย Blocker As Memory Destructor
  152. MetabotropicNmdaย Receptor Function Is Required ForNmdaย Receptor-Dependent Long-Term Depression
  153. MetabotropicNmdaย Receptor Function Is Required For ฮ’-Amyloidโ€“Induced Synaptic Depression
  154. Mglu2/3 Receptor Antagonist, And Ketamine, A Non-CompetitiveNmdaย Receptor Antagonist, In Rodents: Evidence Supporting Use For The Treatment Of Depression
  155. Mice LackingNmdaย Receptors In Parvalbumin Neurons Display Normal Depression-Related Behavior And Response To Antidepressant Action Of Nmdar โ€ฆ
  156. Modulation Of Hippocampal Glutamate And Nmda/Ampa Receptor By Homocysteine In Chronic Unpredictable Mild Stress-Induced Rat Depression
  157. Modulation Of Low-Frequency-Induced Synapticdepressionย In The Developing Ca3โ€“Ca1 Hippocampal Synapses ByNmdaย And Metabotropic Glutamate Receptor โ€ฆ
  158. Muscarinic AndNmdaย Receptors Interaction In The Dorsal Hippocampus Of Rats In The Elevated Plus-Mazeanxietyย Test
  159. Mutant Mice With Reduced Nmda-Nr1 Glycine Affinity Or Lack Of D-Amino Acid Oxidase Function Exhibit Altered Anxiety-Like Behaviors
  160. Nampt Is Required For Long-Termdepressionย And The Function Of Glun2B Subunit-ContainingNmdaย Receptors
  161. NeonatalNmdaย Receptor Blockade Alters Anxiety-And Depression-Related Behaviors In A Sex-Dependent Manner In Mice
  162. Neuroprotectivity Role Of Mk801Nmdaย Receptor Antagonist On Electrical Lesion Of Amygdala Represented In Anxiety-Like Behavior
  163. Nicotinic AndNmdaย Receptors Interaction In The Dorsal Hippocampus Of Rats In The Elevated Plus-Maze Test Of Anxiety
  164. Nmdaย And Dopamine Converge On The Nmda-Receptor To Induce Erk Activation And Synapticdepressionย In Mature Hippocampus
  165. Nmdaย Antagonist Treatment Of Depression
  166. Nmdaย Antagonists For Treatment-Resistant Depression
  167. Nmdaย Antagonists Inhibit Cortical Spreading Depression, But Accelerate The Onset Of Neuronal Depolarization Induced By Asphyxia
  168. Nmdaย Antagonists Ketamine, Memantine And Traxoprodil For Treatment Of Depression: In Vivo Neurochemical Mechanism Of Action
  169. Nmdaย Glutamate Receptor Inhibition In The Dorsal Hippocampus Reduced The Maintenance Of Electric Foot Shock Stress-Inducedanxietyย Anddepressionย Like Behaviors โ€ฆ
  170. Nmdaย Induces Long-Term Synapticdepressionย And Dephosphorylation Of The Glur1 Subunit Of Ampa Receptors In Hippocampus
  171. Nmdaย Receptor Activity In Utero Averts Respiratorydepressionย And Anomalous Long-Termdepressionย In Newborn Mice
  172. Nmdaย Receptor Antagonists Block Heterosynaptic Long-Termdepressionย (Ltd) But Not Long-Term Potentiation (Ltp) In The Ca3 Region Following Lateral Perforant Path โ€ฆ
  173. Nmdaย Receptor Antagonists Block The Induction Of Long-Termdepressionย In The Hippocampal Dentate Gyrus Of The Anesthetized Rat
  174. Nmdaย Receptor Antagonists For Depression: Critical Considerations
  175. Nmdaย Receptor Antagonists For Treatment Of Depression
  176. Nmdaย Receptor Blockade Impairs The Muscarinic Conversion Of Sub-Threshold Transientdepressionย Into Long-Lasting Ltd In The Hippocampusโ€“Prefrontal Cortex Pathway โ€ฆ
  177. Nmdaย Receptor Dependence Of Mgluโ€Mediateddepressionย Of Synaptic Transmission In The Ca1 Region Of The Rat Hippocampus
  178. Nmdaย Receptor Dysregulation In Chronic State: A Possible Mechanism Underlyingdepressionย With Bdnf Downregulation
  179. Nmdaย Receptor Function In Corticotrophin-Releasing Factor Neurons Sex-Dependently Enhances Fear And Increases Sensitivity To Social Stress, Yet Reduces Social Anxiety
  180. Nmdaย Receptor Partial Agonist Glyx-13 Alleviates Chronic Stress-Induced Depression-Like Behavior Through Enhancement Of Ampa Receptor Function In The โ€ฆ
  181. Nmdaย Receptor-Dependent And Metabotropic Glutamate Receptor-Dependent Forms Of Long-Termdepressionย Coexist In Ca1 Hippocampal Pyramidal Cells
  182. Nmdaย Receptor-Dependent And-Independent Long-Termdepressionย In The Ca1 Region Of The Adult Rat Hippocampus In Vitro
  183. Nmdaย Receptor-Dependent Long-Termdepressionย In The Anterior Cingulate Cortex
  184. Nmdaย Receptor-Dependent Long-Term Potentiation And Long-Termdepressionย (Ltp/Ltd)
  185. Nmdaย Receptor-Dependent Long-Term Synapticdepressionย In The Entorhinal Cortex In Vitro
  186. Nmdaย Receptorโ€Dependent Transient Homoโ€And Heterosynapticdepressionย In Picrotoxinโ€Treated Hippocampal Slices
  187. Nmdaย Receptorโ€“Independent Long-Termdepressionย Correlates With Successful Aging In Rats
  188. Nmdaย Receptorโ€Mediated Metaplasticity During The Induction Of Longโ€Termdepressionย By Lowโ€Frequency Stimulation
  189. Nmdaย Receptors Mediate Lasting Increases In Anxiety-Like Behavior Produced By The Stress Of Predator Exposureโ€”Implications Foranxietyย Associated With โ€ฆ
  190. Nmdaย Receptors Mediate Synaptic Depression, But Not Spine Loss In The Dentate Gyrus Of Adult Amyloid Beta (A [Beta]) Overexpressing Mice
  191. Nmdaย Receptors Mediate Synaptic Depression, But Not Spine Loss In The Dentate Gyrus Of Adult Amyloid Beta (Aฮฒ) Overexpressing Mice
  192. Nmdaย Receptors, Mglur5, And Endocannabinoids Are Involved In A Cascade Leading To Hippocampal Long-Term Depression
  193. Nmdaโ€Dependent Heterosynaptic Longโ€Termdepressionย In The Dentate Gyrus Of Anaesthetized Rats
  194. Nmda-Dependent, But Not Group I Metabotropic Glutamate Receptor-Dependent, Long-Termdepressionย At Schaffer Collateralโ€“Ca1 Synapses Is Associated With Long โ€ฆ
  195. Nmda-Independent Long-Termdepressionย Of Synaptic Transmission In The Hippocampus: Mechanisms Of Induction And Effects Of Nootropic Drugs
  196. Nmda-Receptor Activation But Not Ion Flux Is Required For Amyloid-Beta Induced Synaptic Depression
  197. Nmda-Receptor Antagonism Via Dextromethorphan And Ifenprodil Modulates Gradedanxietyย Test Performance Of C57Bl/6 Mice
  198. Nmdaโ€Receptor Blockers But Not Nbqx, An Ampaโ€Receptor Antagonist, Inhibit Spreadingdepressionย In The Rat Brain
  199. N-Methyl-D-Aspartate (Nmda) Antagonists For The Treatment Of Depression
  200. Nr2Aโˆ’/โˆ’ Mice Lack Long-Term Potentiation But RetainNmdaย Receptor And L-Type Ca2+ Channel-Dependent Long-Termdepressionย In The Juvenile Superior Colliculus
  201. Nr3ANmdaย Receptor Subunit Mrna Expression In Schizophrenia,depressionย And Bipolar Disorder
  202. Of Benzo [A] Pyrene (B [A] P) Reduces Anxiety-Related Behaviour In Adult Mice And Modulates Regional Expression Of N-Methyl-D-Aspartate (Nmda) Receptors Genes In โ€ฆ
  203. Of Nmda-Receptors Or Calcium-Channels Attenuates The Ischaemia-Evoked Efflux Of Glutamate And Phosphoethanolamine Anddepressionย Of Neuronal Activity โ€ฆ
  204. On The Linkage Between Ampa AndNmdaย Receptor-Mediated Epsps In Homosynaptic Long-Termdepressionย In The Hippocampal Ca1 Region Of Young Rats
  205. Oral Administration Of TheNmdaย Receptor Antagonist S-Ketamine As Add-On Therapy Of Depression: A Case Series
  206. Orbital Frontal Cortex D1 Dopamine Receptor Modulate Glutamate AndNmdaย Receptor Indepressionย Induced By Chronic Unpredictable Mild Stress
  207. Orexin-A Induces Long-Termdepressionย OfNmdaย Responses In Ca-1 Field Of Hippocampal Slices.
  208. Orphanin Fq SuppressesNmdaย Receptor-Dependent Long-Termdepressionย And Depotentiation In Hippocampal Dentate Gyrus
  209. Perforant Path Kindling,Nmdaย Antagonism, And Late Paired Pulse Depression
  210. Persistent (> 24 H) Long-Termdepressionย In The Dentate Gyrus Of Freely Moving Rats Is Not Dependent On Activation OfNmdaย Receptors, L-Type Voltage-Gated Calcium โ€ฆ
  211. Pharmacological Properties Of Glutamatergic Drugs TargetingNmdaย Receptors And Their Application In Major Depression
  212. Phospholipase C Is Required For Changes In Postsynaptic Structure And Function Associated WithNmdaย Receptor-Dependent Long-Term Depression
  213. Pi3Kฮณ Is Required ForNmdaย Receptorโ€“Dependent Long-Termdepressionย And Behavioral Flexibility
  214. Positive Emotional Learning Induces Resilience To Depression: A Role ForNmdaย Receptor-Mediated Synaptic Plasticity
  215. Postsynaptic Glun2B-ContainingNmdaย Receptors Contribute To Long-Termdepressionย Induction In Medial Vestibular Nucleus Neurons Of Juvenile Rats
  216. Post-Traumatic Stress Disorder (Ptsd) And The Substrates Ofanxietyย Enhancement In The Adult Rat (Flumazenil, Nmda).
  217. Presynaptic Induction And Expression Of Timing-Dependent Long-Termdepressionย Demonstrated By Compartment-Specific Photorelease Of A Use-DependentNmdaย โ€ฆ
  218. PresynapticNmdaย Receptors And Spike Timing-Dependent Long-Termdepressionย At Cortical Synapses
  219. Psd-95 Uncoupling FromNmdaย Receptors By Tat-N-Dimer Ameliorates Neuronal Depolarization In Cortical Spreading Depression
  220. Pten Counteracts Pip3 Upregulation In Spines During Nmda-Receptor-Dependent Long-Term Depression
  221. Pten Is Recruited To The Postsynaptic Terminal ForNmdaย Receptorโ€Dependent Longโ€Term Depression
  222. Ptychodiscus Brevis Toxin-Induceddepressionย Of Spinal Reflexes Involves 5-Ht Via 5-Ht3 Receptors Modulated ByNmdaย Receptor
  223. Quisqualate, Kainate AndNmdaย Can Initiate Spreadingdepressionย In The Turtle Cerebellum
  224. Reduced Levels Of Nr2A And Nr2B Subunits OfNmdaย Receptor And Psd-95 In The Prefrontal Cortex In Major Depression
  225. Regenerative Glutamate Release By PresynapticNmdaย Receptors Contributes To Spreading Depression
  226. Relationship Between Learning And Memory Ability And Expression Of Hippocampal N-Methyl-D-Aspartic Acid (Nmda) In Burn Rats With Depression
  227. Remodelling By Early-Life Stress OfNmdaย Receptor-Dependent Synaptic Plasticity In A Geneโ€“Environment Rat Model Of Depression
  228. Requirement Of Phospholipase C And Protein Kinase C In Cholecystokininโ€Mediated Facilitation OfNmdaย Channel Function And Anxietyโ€Like Behavior
  229. Role Of Calcium, Glutamate AndNmdaย In Majordepressionย And Therapeutic Application
  230. Role Of Different Subunit-Containing Nmda-Receptors In Retinal Spreading Depression
  231. Role Of Hippocampal 5-Ht1A Receptor And Its Modulation ToNmdaย Receptor And Ampa Receptor Indepressionย Induced By Chronic Unpredictable Mild Stress
  232. Role OfNmdaย Antagonists In Animal Models Of Depression
  233. Role Of TheNmdaย Receptor In Cognitive Deficits,anxietyย And Depressive-Like Behavior In Juvenile And Adult Mice After Neonatal Dexamethasone Exposure
  234. Roles OfNmdaย Receptor Nr2A And Nr2B Subtypes For Longโ€Termdepressionย In The Anterior Cingulate Cortex
  235. Selectivedepressionย Of The Spinal Polysynaptic Reflex By TheNmdaย Receptor Antagonists In An Isolated Spinal Cord In Vitro
  236. Simultaneous Expression Of Longโ€Termdepressionย OfNmdaย And Longโ€Term Potentiation Of Ampa Receptorโ€Mediated Synaptic Responses In The Ca1 Area Of The โ€ฆ
  237. Simultaneous Nmda-Dependent Long-Term Potentiation Of Epscs And Long-Termdepressionย Of Ipscs In Cultured Rat Hippocampal Neurons
  238. Spike Timingโ€“Dependent Long-Termdepressionย Requires PresynapticNmdaย Receptors
  239. Spravato (Esketamine) Nasal Spray FirstNmdaย Receptor Antagonist Approved By The Fda For Adults With Treatment-Resistant Depression
  240. Steroid Hormone Secretion After Stimulation Of Mineralocorticoid AndNmdaย Receptors And Cardiovascular Risk In Patients With Depression
  241. Stressor (Fg-7142)-Induced Lasting Increases In Anxiety-Like Behavior: Study 3 The Effects On Amygdala Efferent Physiology Of Block OfNmdaย Receptors Prior To โ€ฆ
  242. Strychnine-Insensitive Glycine/Nmdaย Sites Are Altered In Two Stress Models Of Depression.
  243. Survey OfNmdaย Receptor-Related Biomarkers For Depression
  244. Synapse Regression In Depression: The Role Of 5-Ht Receptors In ModulatingNmdaย Receptor Function And Synaptic Plasticity
  245. Synergistic Action Of Gabaโ€A AndNmdaย Receptors In The Induction Of Longโ€Termdepressionย In Glutamatergic Synapses In The Newborn Rat Hippocampus
  246. Synergisticdepressionย OfNmdaย Receptorโ€Mediated Transmission By Ketamine, Ketoprofen And Lโ€Name Combinations In Neonatal Rat Spinal Cords In Vitro
  247. Targeting OfNmdaย Receptors In The Treatment Of Major Depression
  248. The โ€œBlueโ€ Side Of Glutamatergic Neurotransmission:Nmdaย Receptor Antagonists As Possible Novel Therapeutics For Major Depression
  249. The Co-Expression Of Glun2B Subunits Of TheNmdaย Receptors And Glucocorticoid Receptors After Chronic Restraint Stress In Low And Highanxietyย Rats
  250. The Influence Of Modified Wendan Decoction On Nmda-Nr1 Mrna/Protein Expression In Hippocampus In Rat Model With Depression
  251. TheNmdaย Receptor Complex And The Action Of Antidepressant Drugs In The Cms Model Of Depression
  252. The Role Of Gaba In Nmda-Dependent Long Termdepressionย (Ltd) Of Rat Medial Vestibular Nuclei
  253. The Role Of Glun2A And Glun2B Subunits On The Effects OfNmdaย Receptor Antagonists In Modeling Schizophrenia And Treating Refractory Depression
  254. The Role OfNmdaย Receptor Complex In The Regulation Of Emotional Processes: Looking For New Forms Ofanxietyย Treatment
  255. The Role OfNmdaย Receptors In Long-Term Potentiation (Ltp) Anddepressionย (Ltd) In Rat Visual Cortex
  256. The Role OfNmdaย Receptors In Regulating Group Ii Metabotropic Glutamate Receptor-Mediated Long-Termdepressionย In Rat Medial Prefrontal Cortex
  257. The Role Of Nr2A-And Nr2B-ContainingNmdaย Receptors In Innate Anxiety
  258. Themes: Title: Memory Improvement After Spreadingdepressionย ByNmdaย Blocker As Memory Destructor
  259. Themes: Title: Neuroprotectivity Role Of Mk801Nmdaย Receptor Antagonist On Electrical Lesion Of Amygdala Represented In Anxiety-Like Behavior
  260. TransientNmdaย Receptor Suppression Induces Long-Lasting Synaptic Depression
  261. Treatment-Resistant Major Depression: Rationale ForNmdaย Receptors As Targets And Nitrous Oxide As Therapy
  262. Two Forms Of Long-Termdepressionย In A Polysynaptic Pathway In The Leech Cns: OneNmdaย Receptor-Dependent And The Other Cannabinoid-Dependent
  263. Unilateral Block OfNmdaย Receptors In The Amygdala Prevents Predator Stress-Induced Lasting Increases In Anxiety-Like Behavior And Unconditioned Startleโ€”Effective โ€ฆ
  264. Use-Dependentdepressionย Of SynapticNmdaย Receptor Mediated Responses By Dizocilpine (Mk-801)
  265. What Are The Mechanisms Underlying The Involvement Of Different Subtypes OfNmdaย Receptors In Inducing Long-Term Potentiation Anddepressionย In The Hippocampus?

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Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

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