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Natural Aromatase Inhibitors
Natural Aromatase Inhibitors
… hormonal treatment for vulvovaginal atrophy in women with estrogen receptor-positive breast cancer who are on adjuvant
Aromatase
inhibitor
therapy: meta-analysis
11
Aromatase
inhibitors
2 Recent Developments in
Aromatase
Inhibition as a Potential Treatment for Oestrogen-Dependent Breast Cancer
227 EFFECTS OF A SINGLE DOSE OF A NONSTEROIDAL
Aromatase
INHIBITOR
ON OVARIAN FUNCTION IN CATTLE
4 EFFECT OF A PROLONGED
Aromatase
INHIBITOR
TREATMENT ON PRE-OVULATORY OVARIAN FOLLICLES IN CATTLE
A new class of nonsteroidal
Aromatase
inhibitors
: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes
Aromatase
and 17α …
A novel activity for a group of sesquiterpene lactones: inhibition of
Aromatase
A pilot study comparing the effect of flaxseed,
Aromatase
inhibitor, and the combination on breast tumor biomarkers
Activating mutations of ESR1, BRCA1 and CYP19
Aromatase
genes confer tumor response in breast cancers treated with antiestrogens
Advances in the stereoselective synthesis of antifungal agents and
Aromatase
inhibitors
Anti-
Aromatase
activity of phytochemicals in white button mushrooms (Agaricus bisporus)
Anti-
Aromatase
activity of the constituents from damiana (Turnera diffusa)
Anti‐
Aromatase
Chemicals in Red Wine
Aromatase
activity in quail brain: correlation with aggressiveness
Aromatase
activity in the ovary and brain of the eastern mosquitofish (Gambusia holbrooki) exposed to paper mill effluent.
Aromatase
and 17β-hydroxysteroid dehydrogenase inhibition by flavonoids
Aromatase
inhibition
by an 11, 13-dihydroderivative of a sesquiterpene lactone
Aromatase
inhibition
by flavonoids
Aromatase
inhibition
by synthetic lactones and flavonoids in human placental microsomes and breast fibroblasts—a comparative study
Aromatase
inhibition
: determinants of response and resistance
Aromatase
inhibitor
of formestane and letrozole on sexual differentiation of muscovy [J]
Aromatase
Inhibitor
, Flax seed and Sage Effects on Adult Rats Fertility and Sexual Behavior
Aromatase
inhibitors
and their potential clinical significance
Aromatase
inhibitors
in Breast Cancer: The Discovery of New Compounds by Computational Design and Biochemical Evaluation
Aromatase
inhibitors
in breast cancer: the discovery of new computational design and biochemical evaluation
Aromatase
inhibitors
in cigarette smoke, tobacco leaves and other plants
Aromatase
inhibitors
in the treatment of breast cancer
Aromatase
inhibitors
: a new paradigm in breast cancer treatment
Aromatase
inhibitors
: mechanism of action and role in the treatment of breast cancer
Aromatase
inhibitors
: past, present and future
Aromatase
inhibitors
: rationale and use in breast cancer
Aromatase
inhibitors
: structural features and biochemical characterization
Aromatase
inhibitory
activity of geranylated coumarins, mammeasins C and D, isolated from the flowers of Mammea siamensis
Aromatase
inhibitory
, radical scavenging, and antioxidant activities of depsidones and diaryl ethers from the endophytic fungus Corynespora cassiicola L36
Aromatase
modulation alters gonadal differentiation in developing zebrafish (Danio rerio)
Aromatase
, 3β-HYDROXYSTEROID DEHYDROGENASE Δ5/Δ4 ISOMERASE AND 17β-HYDROXYSTEROID DEHYDROGENASE INHIBITION BY …
Aromatase
,
Aromatase
inhibitors
, and breast cancer
Aromatase
: contributions to physiology and disease in women and men
Assessing effects of
Aromatase
inhibition on fishes with group-synchronous oocyte development using western mosquitofish (Gambusia affinis) as a model
Assessment of chemical effects on
Aromatase
activity using the H295R cell line
Assessment of the
Aromatase
Inhibitory Activity of Ma-Huang-Tang (MHT) and Its Active Compounds
Bis (4-hydroxy-2H-chromen-2-one) coumarin induces apoptosis in MCF-7 human breast cancer cells through
Aromatase
inhibition
Brain
Aromatase
: roles in reproduction and neuroprotection
Cactus flower extracts may prove beneficial in benign prostatic hyperplasia due to inhibition of 5α reductase activity,
Aromatase
activity and lipid peroxidation
Cannabinoid as Potential
Aromatase
Inhibitor Through Molecular Modeling and Screening for Anti-Cancer Activity
Chalcones are potent
inhibitors
of
Aromatase
and 17β-hydroxysteroid dehydrogenase activities
Changes of breast cancer growth and metastasis in murine models modulated by an
Aromatase
inhibitor, a low calcium diet or a high fat diet
Characterization of
Aromatase
binding agents from the dichloromethane extract of Corydalis yanhusuo using ultrafiltration and liquid chromatography tandem mass …
Chemical Constituents from Artemisia annua and Vitex agnus-castus as New
Aromatase
inhibitors
: In-vitro and In-silico Studies
Chemoendocrine metronomic therapy of estrogen receptor-positive breast cancer by taxanes or capecitabine in combination with
Aromatase
inhibitors
Chrysin: is it an effective
Aromatase
inhibitor
Clinical and Genetic Predictors of
Aromatase
Inhibitor-Induced Arthralgia
Coadministrating luteolin minimizes the side effects of the
Aromatase
inhibitor letrozole
Coadministration of the
Aromatase
inhibitor formestane and an isopropanolic extract of black cohosh in a rat model of chemically induced mammary carcinoma
Comparison of the effects of nobiletin and letrozole on the activity and expression of
Aromatase
in the MCF-7 breast cancer cell line
Comprehensive and automated linear interaction energy based binding-affinity prediction for multifarious cytochrome P450
Aromatase
inhibitors
Computational investigations of cytochrome P450
Aromatase
catalysis and biological evaluation of isoflavone
Aromatase
inhibitors
Computational methods for the design of potent
Aromatase
inhibitors
Correlation of rs749292 and rs700518 polymorphisms in the
Aromatase
gene (CYP19A1) with osteoporosis in postmenopausal Polish women
Currently used pesticides and their mixtures affect the function of sex hormone receptors and
Aromatase
enzyme activity
De novo designing, assessment of target affinity and binding interactions against
Aromatase
: Discovery of novel leads as anti-breast cancer agents
Depsidones inhibit
Aromatase
activity and tumor cell proliferation in a co-culture of human primary breast adipose fibroblasts and T47D breast tumor cells
Design, synthesis and activity of flavonoids
Aromatase
inhibitors
Design, synthesis, and 3D QSAR of novel potent and selective
Aromatase
inhibitors
Development of an LC-MS/MS method for
Aromatase
inhibitor screening
Dietary administration of the licorice flavonoid isoliquiritigenin deters the growth of MCF‐7 cells overexpressing
Aromatase
Disruption of
Aromatase
homeostasis as the cause of a multiplicity of ailments: A comprehensive review
Distribution of
Aromatase
activity in brain and peripheral tissues of male sheep: effect of nutrition
Diverse functions of
Aromatase
: O-deethylation of 7-ethoxycoumarin
DNA methylation of the gonadal
Aromatase
(cyp19a) promoter is involved in temperature-dependent sex ratio shifts in the European sea bass
Drugs used for ovarian stimulation: Clomiphene citrate,
Aromatase
inhibitors
, metformin, gonadotropins, gonadotropin-releasing hormone analogs, and recombinant …
Effect of
Aromatase
inhibitors
on the ovarian development of stunted yearlings of rohu (Labeo rohita): a preliminary study
Effect of Buthus martensi Karsch on
Aromatase
Activity and Cytokine-Inducded NOS and NO Production in Osteoblasts and Leukaemic Cell Line FLG 29.1
Effect of Genistein and 2, 3, 7, 8-tetrachlorodibenzo_; 7a/^ a-TCDD On
Aromatase
Activity
Effect of Hop (Humulus lupulus L.) Flavonoids on
Aromatase
(Estrogen Synthase) Activity
Effect of the application of
Aromatase
inhibitors
on sex reversal and zootechnical performance of broiler chicken.
Effective anti-
Aromatase
therapy to battle against estrogen-mediated breast cancer: Comparative SAR/QSAR assessment on steroidal
Aromatase
inhibitors
Effects of a non-steroidal
Aromatase
inhibitor on ovarian function in cattle
Effects of atrazine on CYP19 gene expression and
Aromatase
activity in testes and on plasma sex steroid concentrations of male African clawed frogs (Xenopus laevis …
Effects of atrazine on metamorphosis, growth, laryngeal and gonadal development,
Aromatase
activity, and sex steroid concentrations in Xenopus laevis
Effects of currently used pesticides in assays for estrogenicity, androgenicity, and
Aromatase
activity in vitro
Effects of exposure to oestrogenic compounds on
Aromatase
gene expression are gender dependent in the rainbowfish, Melanotaenia fluviatilis
Effects of Isoflavones on Estrogen Receptor Mediated Estrogenicity and
Aromatase
Activity
Effects of lactone derivatives on
Aromatase
(CYP19) activity in H295R human adrenocortical and (anti) androgenicity in transfected LNCaP human prostate cancer …
Effects of maternal exposure to an
Aromatase
inhibitor on sexual behaviour and neurochemical and endocrine aspects of adult male rat
Effects of neonicotinoids on promoter-specific expression and activity of
Aromatase
(CYP19) in human adrenocortical carcinoma (H295R) and primary umbilical vein …
Effects of nutrition relevant mixtures of phytoestrogens on steroidogenesis,
Aromatase
, estrogen, and androgen activity
Effects of Ovarian Development by P450
Aromatase
Activity Controled in Mice [J]
Effects of phytoestrogens on
Aromatase
, 3β and 17β-hydroxysteroid dehydrogenase activities and human breast cancer cells
Effects of the
Aromatase
inhibitor fadrozole on gene expression in the zebrafish brain
Efficacy of cactus flowers miller treatment in benign prostatic hyperplasia due to inhibition of 5α reductase activity,
Aromatase
activity and lipid peroxidation.
Efficacy of management strategies for
Aromatase
inhibitor‐induced arthralgia in breast cancer patients: a systematic review
Egonol gentiobioside and egonol gentiotrioside from Styrax perkinsiae promote the biosynthesis of estrogen by
Aromatase
Emerging Chemicals Targeting
Aromatase
: Protective Compounds or Endocrine Disruptors?
Enhanced Expression of
Aromatase
in Tamoxifen Resistant Human Breast Cancer
Enzymatic control of estrogen production in human breast cancer: relative significance of
Aromatase
versus sulfatase pathways
Ergostane-type sterols from king trumpet mushroom (Pleurotus eryngii) and their inhibitory effects on
Aromatase
Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and
Aromatase
in …
Evaluation of a 40 day assay for testing endocrine disrupters: effects of an anti-estrogen and an
Aromatase
inhibitor on sex ratio and vitellogenin concentrations in …
Evaluation of Synthesized Ester or Amide Coumarin Derivatives on
Aromatase
Inhibitory Activity
Evaluation of the
Aromatase
Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas)
Evaluation of the biochemical activity of new modified steroids as
Aromatase
inhibitors
Evaluation of the biochemical activity of new modified steroids as
Aromatase
inhibitors
Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on
Aromatase
inhibition
Everolimus downregulates estrogen receptor and induces autophagy in
Aromatase
inhibitor-resistant breast cancer cells
Extraction, isolation, and
Aromatase
inhibitory evaluation of low-polar ginsenosides from Panax ginseng leaves
Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of
Aromatase
for the treatment of estrogen-dependent disease
Fetal safety profile of
Aromatase
inhibitors
: Animal data
Flavans from Desmos cochinchinensis as potent
Aromatase
inhibitors
Flavonoid inhibition of
Aromatase
enzyme activity in human preadipocytes
GBEs as an
Aromatase
Inhibitor for Hormone Adjuvant Therapy
Genistein induces breast cancer-associated
Aromatase
and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model
Growth inhibitory efficacy and anti‑
Aromatase
activity of Tabebuia avellanedae in a model for post‑menopausal Luminal A breast cancer
Hexanol Extracts of Cyperus Rotundus Inhibited
Aromatase
Activity in JEG-3 Cells
HUMAN
Aromatase
GENE EXPRESSION IN ADIPOSE TISSUE
Hypothalamic–pituitary–gonadal axis in two men with
Aromatase
deficiency: evidence that circulating estrogens are required at the hypothalamic level for the …
Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by
Aromatase
(CYP19)
Identification of endocrine disrupting chemicals acting on human
Aromatase
Impairment of spermatogenesis in mice lacking a functional
Aromatase
(cyp 19) gene
In silico Docking Approach of Coumarin Derivatives as an
Aromatase
Antagonist
Incidence of menopausal symptoms in postmenopausal breast cancer patients treated with
Aromatase
inhibitors
Increased sperm cell production in ageing roosters by an oral treatment with an
Aromatase
inhibitor and a
natural
herbal extract designed for improving fertility
Induction and inhibition of
Aromatase
(CYP19) activity by
natural
and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells
Inhibition of
Aromatase
and cell proliferation of breast cancer and human placenta choriocarcinoma by Prunus persica extracts
Inhibition of
Aromatase
and α-Amylase by Flavonoids and Proanthocyanidins from Sorghum bicolor Bran Extracts
Inhibitory
Aromatase
effects of flavonoids from Ginkgo biloba extracts on estrogen biosynthesis
Inhibitory effect of chrysin on estrogen biosynthesis by suppression of enzyme
Aromatase
(CYP19): A systematic review
Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of
Aromatase
(CYP19)
Inhibitory effect of Sphagnum palustre extract and its bioactive compounds on
Aromatase
activity
Inhibitory effects of Ginkgo biloba extract on
Aromatase
activity and tumor suppression in
Aromatase
xenograft model
Integrated in silico-in vitro strategy for screening of some traditional Egyptian plants for human
Aromatase
inhibitors
Interference of endocrine disrupting chemicals with
Aromatase
CYP19 expression or activity, and consequences for reproduction of teleost fish
Interrelationships between
Aromatase
and cyclooxygenase-2 and their role in the autocrine and paracrine mechanisms in breast cancer
Investigating the Effects of
Aromatase
inhibitors
on the Musculoskeletal System
Lead molecules as novel
Aromatase
inhibitors
: in silico de novo designing and binding affinity studies
Levels of
Aromatase
and Estrogen Receptors mRNA in Early Larvae of Alburnus tarichi (Güldenstӓdt, 1814) Exposed to Di-(2-ethylhexyl)-phthalate
Luteolin-7-methylether from Leonurus japonicus inhibits estrogen biosynthesis in human ovarian granulosa cells by suppression of
Aromatase
(CYP19)
Mammalian lignans and genistein decrease the activities of
Aromatase
and 17β-hydroxysteroid dehydrogenase in MCF-7 cells
Management of sexual dysfunction in postmenopausal breast cancer patients taking adjuvant
Aromatase
inhibitor therapy
Mechanism and inhibition of cytochrome P-450
Aromatase
Modulation of
Aromatase
activity as a mode of action for endocrine disrupting chemicals in a marine fish
Modulation of
Aromatase
by
natural
compounds—A pharmacophore guided molecular modelling simulations
Modulation of
Aromatase
by phytoestrogens
Molecular basis for the interaction of four different classes of substrates and
inhibitors
with human
Aromatase
Molecular cloning and developmental expression of
Aromatase
s gene in two species of loaches
Molecular docking studies on borapetol with target
Aromatase
related to breast cancer
Molecular Modelling of Estrogen-Producing Enzymes CYP450
Aromatase
and 17beta-Hydroxysteroid Dehydrogenase Type 1
Molecular pharmacology of
Aromatase
and its regulation by endogenous and exogenous agents
Musculoskeletal side effects of
Aromatase
inhibitors
treatment in women with breast cancer
natural
product compounds with
Aromatase
inhibitory activity: an update
natural
products as
Aromatase
inhibitors
: Identification and structure-activity aspects
Nelumal A, the Active Principle of Ligularia nelumbifolia, is a Novel
Aromatase
Inhibitor
New 7, 8-benzoflavanones as potent
Aromatase
inhibitors
: synthesis and biological evaluation
No evidence for the in vivo activity of
Aromatase
-inhibiting flavonoids
No indications of socially induced changes in brain
Aromatase
activity in guppy (Poecilia reticulata) males
Nonsteroidal
Aromatase
inhibitors
for the treatment of breast cancer: an update
Nonsteroidal
Aromatase
inhibitors
: recent advances
Novel inhibitor discovery against
Aromatase
through virtual screening and molecular dynamic simulation: a computational approach in drug design
Novel irreversible
Aromatase
inhibitors
Nutrigenomics-associated impacts of nutrients on genes and enzymes with special consideration of
Aromatase
Optimization of the
Aromatase
inhibitory activities of pyridylthiazole analogues of resveratrol
Origin of
Aromatase
inhibitory activity via proteochemometric modeling
P450
Aromatase
alterations and DNA damage as avian pollution biomarkers in cliff and cave swallow breeding near the Rio Grande region, Texas
Pattern of
Aromatase
mRNA expression in the brain of a weakly electric fish, Apteronotus leptorhynchus
Pharmacophore mapping of flavone derivatives for
Aromatase
inhibition
Phytochemicals for breast cancer prevention by targeting
Aromatase
Phytoestrogens inhibit
Aromatase
but not 17β‐hydroxysteroid dehydrogenase (HSD) type 1 in human granulosa‐luteal cells: evidence for FSH induction of 17β‐HSD
PLACENTAL
Aromatase
ASSAY VALIDATION STUDY: POSITIVE CONTROL STUDY
Potential effect of Olea europea leaves, Sonchus oleraceus leaves and Mangifera indica peel extracts on
Aromatase
activity in human placental microsomes and …
Potential effects of environmental contaminants on P450
Aromatase
activity and DNA damage in swallows from the Rio Grande and Somerville, Texas
Potential utility of
natural
products as regulators of breast cancer-associated
Aromatase
promoters
PRE-VALIDATION STUDY PLAN AND STUDY PROTOCOL FOR THE
Aromatase
ASSAY USING HUMAN, BOVINE, AND PORCINE PLACENTA, AND …
Probing the origins of
Aromatase
inhibitory activity of disubstituted coumarins via QSAR and molecular docking
Probing the xeno-oestrogenic impact of sediment cores contaminated by the pulp and paper industry: induction of
Aromatase
cyp19a1b in late larval zebrafish
Prostaglandin E2-9-Ketoreductase and Prostaglandin F2α Activate Brain
Aromatase
to Induce Courtship in the Male Crested Newt, Triturus carnifex
QSAR modeling of
Aromatase
inhibitory activity of 1-substituted 1, 2, 3-triazole analogs of letrozole
QSAR study of diarylalkylimidazole and diarylalkyltriazole
Aromatase
inhibitors
Quillaja saponins inhibit tilapia
Aromatase
activity in vitro
Randomized, double-blind, placebo-controlled phase ii clinical trial on the use of uncaria tomentosa (Cat’s claw) for
Aromatase
inhibitor-induced arthralgia: A pilot …
Recent advancement in nonsteroidal
Aromatase
inhibitors
for treatment of estrogen-dependent breast cancer
Recent Studies on
Aromatase
and Sulfatase Involved in Breast Cancer and their
inhibitors
Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on
Aromatase
gene expression and reproduction using novel …
Regulation of
Aromatase
expression in breast cancer tissue
Role of EGB 761 as a Possible
Aromatase
Inhibitor for Breast Cancer Therapy
Role of estrogen receptors and
Aromatase
on brain protein synthesis rates in ovariectomized female rats fed genistein
Screening for
Aromatase
ligands in the extract of Broussonetia papyrifera using high performance liquid chromatography and ESI-mass spectrometry
Screening of herbal constituents for
Aromatase
inhibitory activity
Selection of Appropriate Inhibitor for Ovarian Type Cytochrome P450
Aromatase
Gene of Heteropneustesfossilis with the Application of Homology Modeling …
Selective Inhibition of
Aromatase
by a Dihydroisocoumarin from Xyris pterygoblephara
Sensitivity of New Zealand mudsnail Potamopyrgus antipodarum (Gray) to a specific
Aromatase
inhibitor
Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an
Aromatase
inhibitor
Steroid and growth factor modulation of
Aromatase
activity in MCF7 and T47D breast carcinoma cell lines
Steroidal alkaloids efficient
Aromatase
inhibitors
with potential for the treatment of postmenopausal breast cancer
Structure–function studies of
Aromatase
and its
inhibitors
: a progress report
Superiority of
Aromatase
inhibitor and cyclooxygenase-2 inhibitor combined delivery: hyaluronate-targeted versus PEGylated protamine nanocapsules for breast …
Suppression of
Aromatase
(estrogen synthetase) by red wine phytochemicals
Suppression of
Aromatase
activity in populations of bream (Abramis brama) from the river Elbe, Germany
Synthesis and
Aromatase
inhibition properties of new boronic acid chalcone derivatives
Synthesis and
Aromatase
inhibitory activity of novel pyridine-containing isoflavones
Synthesis and biological evaluation of (±)-abyssinone II and its analogues as
Aromatase
inhibitors
for chemoprevention of breast cancer
Synthesis of
Aromatase
inhibitors
and quinone reductase inducers for cancer chemoprevention studies
Synthesis of casimiroin and optimization of its quinone reductase 2 and
Aromatase
inhibitory activities
Synthesis of dl-standishinal and its related compounds for the studies on structure–activity relationship of inhibitory activity against
Aromatase
Synthesis of enterolactone and enterodiol precursors as potential
inhibitors
of human estrogen synthetase (
Aromatase
)
Synthetic isoflavones and doping: A novel class of
Aromatase
inhibitors
?
Tebuconazole Disrupted
Aromatase
Activity and Reduced 17β-Estradiol Concentration in Pubertal Developmental Rats
Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by
Aromatase
in endothelial cells: implications in atherosclerosis
Thalassosterol, a new cytotoxic
Aromatase
inhibitor ergosterol derivative from the Red Sea seagrass Thalassodendron ciliatum
The citrus flavonone hesperetin inhibits growth of
Aromatase
-expressing MCF-7 tumor in ovariectomized athymic mice
The combined effects of temperature and
Aromatase
inhibitor on metamorphosis, growth, locomotion, and sex ratio of tiger frog (Hoplobatrachus rugulosus) …
The Effect of in ovo Injection of
Aromatase
inhibitors
on the Performance of Broilers
The effects of Nobiletin, Hesperetin, and Letrozole in a combination on the activity and expression of
Aromatase
in breast cancer cells
The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of
Aromatase
gene expression
The phenotype of the
Aromatase
knockout mouse reveals dietary phytoestrogens impact significantly on testis function
The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing
Aromatase
The red wine polyphenol resveratrol displays bilevel inhibition on
Aromatase
in breast cancer cells
The roles of sex steroids and their receptors in the regulation of brain
Aromatase
expression
The use of
Aromatase
inhibitors
in boys with short stature: what to know before prescribing?
The use of the Klopman index as a new descriptor for pharmacophore analysis on strong
Aromatase
inhibitor flavonoids against estrogen-dependent breast cancer
Total syntheses of the
Aromatase
inhibitors
, mammeasins C and D, from Thai medicinal plant Mammea siamensis
Total synthesis of the
Aromatase
inhibitor dihydroisocoumarin via protective opening of lactones
Towards understanding
Aromatase
inhibitory activity via QSAR modeling
White button mushroom phytochemicals inhibit
Aromatase
activity and breast cancer cell proliferation
α-Glucosidase inhibitory,
Aromatase
inhibitory, and antiplasmodial activities of a biflavonoid GB1 from Garcinia kola stem bark
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