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Mcl-1

  1. 12P Individualized Breast Cancer Therapy Using Mcl-1 Inhibition Based Combination
  2. 155: Trem-1 Protects Monocyte From Apoptosis Via Mcl-1-Dependent Mechanism
  3. 1-Phenyl-1H-Indole Derivatives As A New Class Of Bcl-2/Mcl-1 Dual Inhibitors: Design, Synthesis, And Preliminary Biological Evaluation
  4. 2-Deoxyglucose Pretreatment Sensitizes Colon Cancer Cells To Cisplatin And Killer Trail Induced Apoptosis By Mcl-1 Downregulation
  5. 3656: Apoptosis In Human Cancer Cells In A Bcl-Xl, Bcl2 And Mcl-1 …
  6. 3-Bromopyruvate Induces Apoptosis In Breast Cancer Cells By Downregulating Mcl-1 Through The Pi3K/Akt Signaling Pathway
  7. 3-Substituted-N-(4-Hydroxynaphthalen-1-Yl)Arylsulfonamides As A Novel Class Of Selective Mcl-1 Inhibitors: Structure-Based Design, Synthesis, Sar, And Biological …
  8. 3-Thiomorpholin-8-Oxo-8H-Acenaphtho [1, 2-B] Pyrrole-9-Carbonitrile (S1) Derivatives As Pan-Bcl-2-Inhibitors Of Bcl-2, Bcl-Xl And Mcl-1
  9. 5-Fluorouracil Induction Of Fas And Apoptosis In Colon Cancer Patients: Relation Of Clinical Outcome With Thymidylate Synthase, Mcl-1 And Rb
  10. 7-Isopenthenyloxycoumarin, Arctigenin, And Hesperidin Modify Myeloid Cell Leukemia Type-1 (Mcl-1) Gene Expression By Hormesis In K562 Cell Line
  11. A Chemotherapy-Driven Increase In Mcl-1 Mediates The Effect Of Mir-375 On Cisplatin Resistance In Osteosarcoma Cells.
  12. A Competitive Stapled Peptide Screen Identifies A Selective Small Molecule That Overcomes Mcl-1-Dependent Leukemia Cell Survival
  13. A Critical Epithelial Survival Axis Regulated By Mcl-1 Maintains Thymic Function
  14. A Critical Epithelial Survival Axis Regulated By Mcl-1 Maintains Thymic Function In Mice
  15. A Inhibits Sodium Nitroprusside-Induced Cardiac H9C2 Cell Death Through Suppressing Activation Of Jnk And Preserving Mitochondrial Anti-Apoptotic Bcl-2 And Mcl-1
  16. A Kinase Inhibitor Screen Identifies Mcl-1 And Aurora Kinase A As Novel Treatment Targets In Antiestrogen-Resistant Breast Cancer Cells
  17. A Luciferase-Based Assay Identifies Niclosamide Derivatives Antagonizing Mcl-1 Through Post-Translational Down-Regulation
  18. A Major Role For Mcl-1 Antiapoptotic Protein In The Il-6-Induced Survival Of Human Myeloma Cells
  19. A Non-Apoptotic Function For Mcl-1 As An Activator Of Canonical Wnt Signaling In Keratinocytes
  20. A Non-Apoptotic Function Of Mcl-1 In Promoting Pluripotency And Modulating Mitochondrial Dynamics In Stem Cells
  21. A Novel Allosteric Mechanism For Molecular Inhibition Of Anti-Apoptotic Mcl-1
  22. A Novel Atp-Competitive Mek/Aurora Kinase Inhibitor Bi-847325 Reverses Acquired Braf Inhibitor Resistance Through Suppression Of Mcl-1 And Inhibition Of Mek …
  23. A Novel Bh 3 Mimetic Efficiently Induces Apoptosis In Melanoma Cells Through Direct Binding To Anti‐Apoptotic Bcl‐2 Family Proteins, Including Phosphorylated Mcl‐1
  24. A Novel Bh3 Ligand That Selectively Targets Mcl-1 Reveals That Apoptosis Can Proceed Without Mcl-1 Degradation
  25. A Novel Bh3 Mimetic S1 Potently Induces Bax/Bak‐Dependent Apoptosis By Targeting Both Bcl‐2 And Mcl‐1
  26. A Novel Biomarker Approach In Mcl-1 Dependent Relapsed/Refractory Aml
  27. A Novel Histone Deacetylase Inhibitor, Cg200745, Potentiates Anticancer Effect Of Docetaxel In Prostate Cancer Via Decreasing Mcl-1 And Bcl-Xl
  28. A Novel Pan Inhibitor Of Bcl-2 And Mcl-1 Apogossypolone (Apog2) With Superior Stability And Improved Activity Against Human Leukemia And Lymphoma Cells.
  29. A Novel Selective Mcl-1 Inhibitor Exhibits In Vitro And In Vivo Efficacy In Melanoma
  30. A Novel Small Molecule Fl118 That Selectively Inhibits Survivin, Mcl-1, Xiap And Ciap2 In A P53-Independent Manner, Shows Superior Antitumor Activity
  31. A Novel Small-Molecule Iap Antagonist, Azd5582, Draws Mcl-1 Down-Regulation For Induction Of Apoptosis Through Targeting Of Ciap1 And Xiap In Human …
  32. A Novel Small-Molecule Inhibitor Of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro And In Vivo
  33. A Noxa/Mcl‐1 Imbalance Underlies Chemoresistance Of Malignant Rhabdoid Tumor Cells
  34. A Phase 1, First-In-Human Study Of Amg 176, A Selective Mcl-1 Inhibitor, In Patients With Relapsed Or Refractory Multiple Myeloma
  35. A Pivotal Role For Mcl-1 In Bortezomib-Induced Apoptosis
  36. A Proteolytic Fragment Of Mcl-1 Exhibits Nuclear Localization And Regulates Cell Growth By Interaction With Cdk1
  37. A Same Day Assay Using Cytochrome C Release Determines Sensitivity To Cooperative Bcl-2 And Mcl-1 Targeting In Multiple …
  38. A Short Term Biomarker-Based Assay Predicts Apoptotic Response To Combined Bcl-2/Mcl-1 Bh3 Mimetic Targeting In Myeloma Cells
  39. A Small Molecule Cyclin Dependent Kinase Inhibitor, Overcomes Drug Resistance Via Down-Regulation Of Mcl-1 In Multiple Myeloma (Mm)
  40. A Stapled Bim Bh3 Helix Overcomes The Mcl-1-Mediated Apoptotic Blockade Of Refractory Hematologic Cancers
  41. A Study Of Myc And Mcl-1 Transcript Levels Before And During Tyrosine Kinase Inhibitor Therapy In Chronic Myeloid Leukemia Patients
  42. A Subset Of Small Cell Lung Cancer (Sclc) Cell Lines Are Mcl-1-Dependent And Undergo Apoptosis In Response To Flavopiridol-Mediated Inhibition Of Cyclin-Dependent …
  43. A Subset Of Small Cell Lung Cancer (Sclc) Cell Lines Is Mcl-1-Dependent And Responds To Cyclin-Dependent Kinase (Cdk) 9 Inhibition In Vitro And In Vivo
  44. A Subunit Of The Mammalian Oligosaccharyltransferase, Dadi, Interacts With Mcl-1, One Of The Bcl-2 Protein Family
  45. A‑1210477, A Selective Mcl‑1 Inhibitor, Overcomes Abt‑737 Resistance In Aml
  46. Absence Of Macrophage Mcl-1 Induces Foam Cell Formation And Atherosclerotic Plaque Apoptosis Without Affecting Plaque Development In Ldlr−/− Mice
  47. Abstract A021: Genipin Enhanced Apoptosis Of Gastric Cancer By Mitochondrial Dysfunction And Downregulation Of Stat3/Jak2/Mcl-1 Signaling Pathway
  48. Abstract A23: Noxa Determines Localization And Stability Of Mcl-1 And Consequently Abt-737 Sensitivity In Small Cell Lung Cancer.
  49. Abstract A60: Mcl-1 Confers Protection Of Her2-Positive Breast Cancer Cells To Hypoxia: Therapeutic Implications
  50. Abstract A65: A Novel Small-Molecule Iap Antagonist, Azd5582, Draws Mcl-1 Down-Regulation For Induction Of Apoptosis Through Targeting Of Ciap1 And Xiap In Human …
  51. Abstract A65: Combinational Sirna Silencing Of Mcl-1 And P-Gp Enhances The Apoptotic Response In Human Breast Cancer Cells
  52. Abstract B07: Mcl-1-Mediated Resistance To Abt-263 Is Combated By Mtor Inhibition In Luminal Breast Cancers
  53. Abstract B071: Targeting The Antiapoptotic Protein Mcl-1 In Luminal B Breast Cancers
  54. Abstract B09: Mcl-1 Inhibition Improves Abt199 Efficacy For Bcl-2-Dependent Neuroblastoma
  55. Abstract B09: Targeting The Anti-Apoptotic Protein Mcl-1 With The Mtor Inhibitor Rad001 Sensitizes Luminal Breast Cancers To The Bcl-2/Bcl-Xl Inhibitor Abt-263
  56. Abstract B17: Synergism Between P53 And Mcl-1 In Hepatocyte Maturation And Survival
  57. Abstract B26: Targeting Glucose And Glutamine Metabolism In Melanoma Cells Influences Noxa And Mcl‐1 Levels As Well As Susceptibility To Trail‐Induced Apoptosis
  58. Abstract B76: Targeting Mcl-1 For Radiosensitization Of Pancreatic Cancers
  59. Abstract B89: The Effects Of Raf Kinase Inhibition With Either Sorafenib Or Plx‐4720 On Mcl‐1 Expression And Cytotoxicity Alone And In Combination With Abt‐737 In …
  60. Abstract C212: Discovery Of High Affinity Cyclic Peptidomimetics Binding Mcl-1 And Ras.
  61. Abstract C263: Mtor Inhibition Specifically Sensitizes Colorectal Cancers With Kras Or Braf Mutations To Bcl-2/Bcl-Xl Inhibition By Suppressing Mcl-1.
  62. Abstract C40: Inhibition Of Mcl-1 Through Covalent Modification Of A Non-Catalytic Lysine Side Chain
  63. Abstract C41: Targeting The Antiapoptotic Protein Mcl-1 In Glioblastoma Multiforme
  64. Abstract C48: Dual Targeting Of Myeloma Cells By 2-Deoxy-D-Glucose And Abt-199 Combination Respectively Through The Down-Regulation Of Mcl-1 And Binding To Bcl-2 …
  65. Abstract C75: Overcoming Kras/Lkb1 Mutant Nsclc Resistance To Bet Bromodomain Inhibitors With Gemcitabine Or Mcl-1 Inhibition
  66. Abstract Cn04-02: Discovery Of Mcl-1 Inhibitors Using Fragment-Based Methods.
  67. Abstract Ddt01-01: The Discovery And Preclinical Characterization Of Amg 176: A First-In-Class Mcl-1 Inhibitor In Clinical Development For Multiple Myeloma
  68. Abstract Ddt01-02: Azd5991: A Potent And Selective Macrocyclic Inhibitor Of Mcl-1 For Treatment Of Hematologic Cancers
  69. Abstract Ia02: Mcl-1 Inhibitors For The Treatment Of Cancer
  70. Abstract Lb-212: Mcl-1 And Fbw7 Control A Dominant Survival Pathway Underlying Hdac And Bcl-2 Inhibitor Synergy In Squamous Cell Carcinoma.
  71. Abstract Lb-72: An Immunoassay Detecting Bcl-2: Bim And Mcl-1: Bim Complexes In The Phase 1 Monotherapy Study Of The Bcl-2 Inhibitor, Abt-199/Gdc-0199, In …
  72. Abstract Lb-79: Synergistic Anticancer Effects Of The 9.2. 27Pe Immunotoxin And Abt-737 In Melanoma Involves Silencing Of The Anti-Apoptotic Protein Mcl-1
  73. Abstract P042: Loss Of Mcl-1 In The Heart Leads To Rapid Mitochondrial Dysfunction And Development Of Heart Failure
  74. Abstract P43: A Distinct Region Of Mcl-1 Defines Its Antisenescent Properties
  75. Abstract Sy16-02: The Discovery Of Mcl-1 Inhibitors Using Fragment-Based Methods And Structure-Based Design
  76. Abstract# 1801: Sns-032 Reduced The Expression Of Cyclin D1 And Mcl-1 And Inhibited Survival In Mantle Cell Lymphoma Cell Lines
  77. Abstract# 1815: Homoharringtonine Down-Regulates Mcl-1 And Induces Apoptosis In Chronic Lymphocytic Leukemia Cells
  78. Abstract# 3272: Regulation Of Mcl-1 And Its Contribution To Cell Survival And Drug Resistance In Breast Cancer
  79. Abstract# 3275: Up-Regulation Of Mcl-1 Via Xbp1-Mediated Activation Of Akt Is Critical For Survival Of Melanoma Cells Upon Er Stress
  80. Abstract# 3276: The Bh3 Mimetic Obatoclax (Gx15-070) Sensitized B-Nhl Cells To Trail-Mediated Apoptosis By Activating Bak And Inhibiting Mcl-1, Nf-\# 954; B And …
  81. Abstract# 3284: Nicotine Enhances The Antiapoptotic Function Of Mcl-1 Through Phosphorylation
  82. Abstract# 3693: Sorafenib Inhibits Stat3-Regulated Expression Of Prosurvival Mcl-1 And Bcl-Xl Proteins To Enhance Trail-Mediated Apoptosis In Human Pancreatic …
  83. Abstract# 3867: Degradation Of The Anti-Apoptotic Protein Mcl-1 Correlates With Mitotic Cell Death In Response To The Novel Ksp Inhibitor Arry-520.
  84. Abstract# 4601: Phosphorylation And Degradation Of Mcl-1 In Vinblastine-Induced Apoptosis
  85. Accumulation Of The Pro-Apoptotic Factor Bak Is Controlled By Antagonist Factor Mcl-1 Availability
  86. Acoustic Overstimulation Modifies Mcl‐1 Expression In Cochlear Sensory Epithelial Cells
  87. Acquired Activation Of The Akt/Cyclooxygenase-2/Mcl-1 Pathway Renders Lung Cancer Cells Resistant To Apoptosis
  88. Acquired Apoptosis Resistance Mediated By Activation Of The Akt/Cox-2/Mcl-1 Pathway In Lung Cancer Cells
  89. Acquired Resistance To Abt-737 In Lymphoma Cells That Up-Regulate Mcl-1 And Bfl-1
  90. Actinidia Arguta (Hardy Kiwi) Root Extract Exerts Anti-Cancer Effects Via Mcl-1-Mediated Apoptosis In Cholangiocarcinoma
  91. Actinomycin D Decreases Mcl-1 Expression And Acts Synergistically With Abt-737 Against Small Cell Lung Cancer Cell Lines
  92. Actinomycin D Synergistically Enhances The Efficacy Of The Bh3 Mimetic Abt-737 By Downregulating Mcl-1 Expression
  93. Activating Transcription Factor-6 (Atf6) Mediates Apoptosis With Reduction Of Myeloid Cell Leukemia Sequence 1 (Mcl-1) Protein Via Induction Of Ww Domain Binding …
  94. Activation By Fmlp Regulates Foxo (Forkhead) Transcription Factors By Multiple Pathways, One Of Which Includes The Binding Of Foxo To The Survival Factor Mcl‐1
  95. Activation Of Atf4 Mediates Unwanted Mcl-1 Accumulation By Proteasome Inhibition
  96. Activation Of The Camp Signaling Pathway Increases Apoptosis In Human B‐Precursor Cells And Is Associated With Downregulation Of Mcl‐1 Expression
  97. Activation Of The Camp Signaling Pathway Induces Apoptosis In Human B-Precursor Cells And Is Associated With Downregulation Of Mcl-1 Expression
  98. Activity Of Bortezomib Against Multiple Myeloma (Mm) Through Inhibition Of Interleukin (Il)-6 Signaling: A Role For Repression Of Myeloid Cell Leukemia (Mcl)-1.
  99. Activity Of The Selective Bcl-2 Inhibitor Abt-199 In Childhood B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By Mcl-1/Bcl-2 Expression Serving …
  100. Acute Myeloid Leukemia Possessing Jumping Translocation Is Related To Highly Elevated Levels Of Eat/Mcl-1, A Bcl-2 Related Gene With Anti-Apoptotic Functions
  101. Adaptation To Er Stress As A Driver Of Increased Expression Of Mcl-1 With Melanoma Progression
  102. Adenovirus-Mediated Short Hairpin Rna (Shrna) Suppresses Mcl-1 Expression Enhancing Apoptosis Sensitivity In Gastric Cancer Cells.
  103. Adenovirus-Mediated Sirna Targeting Mcl-1 Gene Increases Radiosensitivity Of Pancreatic Carcinoma Cells In Vitro And In Vivo
  104. Adsorption Of 1, 2, 3-Trichloropropane (Tcp) To Meet A Mcl Of 5 Ppt
  105. Afatinib Down-Regulates Mcl-1 Expression Through The Perk-Eif2Α-Atf4 Axis And Leads To Apoptosis In Head And Neck Squamous Cell Carcinoma
  106. Affinities Of Mcl-1 And Bcl-Xl For Bh3-Only Proteins Define Distinct Survival Functions At The Outer Mitochondrial Membrane Of Multiple Myeloma Cells.
  107. Age-Related Changes In The Ratio Of Mcl-1/Bax Expression In The Rat Cochlea
  108. Aggravates Cardiac Apoptosis In L-Name-Induced Pressure Overload Model In Rats: Immunohistochemical Determination Of Cardiac Caspase-3, Mcl-1, Bax And Bcl-2
  109. Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis To Maintain Cell Survival And Resistance To Bcl-2 Inhibition
  110. Akt-Mediated Eminent Expression Of C-Flip And Mcl-1 Confers Acquired Resistance To Trail-Induced Cytotoxicity To Lung Cancer Cells
  111. Alcohol‐Mediated Missplicing Of Mcl‐1 Pre‐Mrna Is Involved In Neurotoxicity
  112. Alkaloids From Piper Nigrum Synergistically Enhanced The Effect Of Paclitaxel Against Paclitaxel-Resistant Cervical Cancer Cells Through The Downregulation Of Mcl-1
  113. Allosteric Inhibition Of Antiapoptotic Mcl-1
  114. Alpha2Beta1 Integrin Promotes T Cell Survival And Migration Through The Concomitant Activation Of Erk/Mcl-1 And P38 Mapk Pathways
  115. Alterations In The Noxa/Mcl-1 Axis Determine Sensitivity Of Small Cell Lung Cancer To The Bh3 Mimetic Abt-737
  116. Alvocidib Potentiates The Activity Of Azacytidine In An Mcl-1-Dependent Fashion
  117. Alvocidib Potentiates The Activity Of Cytarabine And Mitoxantrone Through The Targeting Of Mcl-1 When Administered In A Time Sequential Regimen In Aml
  118. Amg-176, An Mcl-1 Antagonist, Shows Preclinical Efficacy In Chronic Lymphocytic Leukemia
  119. Aml Sensitivity To Ym155 Is Modulated Through Akt And Mcl-1
  120. Amp‐Activated Protein Kinase (Ampk)–Induced Preconditioning In Primary Cortical Neurons Involves Activation Of Mcl‐1
  121. Ampk-Mediated Up-Regulation Of Mtorc2 And Mcl-1 Compromises The Anti-Cancer Effects Of Aspirin
  122. An Essential Role For Mcl-1 In Atr-Mediated Chk1 Phosphorylation
  123. An Internal Eeld Domain Facilitates Mitochondrial Targeting Of Mcl-1 Via
  124. An Internal Eeld Domain Facilitates Mitochondrial Targeting Of Mcl-1 Via A Tom70-Dependent Pathway
  125. An Intravenous (Iv) Route-Compatible Formulation Of Fl118, A Survivin, Mcl-1, Xiap, And Ciap2 Selective Inhibitor, Improves Fl118 Antitumor Efficacy And …
  126. An Rna Interference Screen Reveals A Critical Role For Mcl-1 In Survival Of Cml Progenitor Cells.
  127. Anacardic Acids From Knema Hookeriana As Modulators Of Bcl-Xl/Bak And Mcl-1/Bid Interactions
  128. Analysis Of Antioxidant Enzymes Combined With The Detection Of Mcl-1 And Bax Expressions In Acute Childhood Leukemias
  129. Analysis Of Flexibility And Hotspots In Bcl-Xl And Mcl-1 Proteins For The Design Of Selective Small-Molecule Inhibitors
  130. Analyzing The Therapeutic Efficacy Of Navitoclax And Mcl-1 Inhibitors In Juvenile Myelomonyctic Leukemia
  131. And Cysteamine Supplementation During In Vitro Production Of Buffalo (Bubalus Bubalis) Embryos Affect Mrna Expression Of Bcl‐2, Bcl‐Xl, Mcl‐1, Bax And Bid
  132. And Metastatic Potential In Preclinical Models Of Osteosarcoma Through A Mechanism Potentially Involving The Inhibition Of Erk1/2, Mcl-1 And Ezrin Pathways
  133. And Sphingosine Kinase Inhibitor Interact Synergistically To Induces Apoptosis In Bcr/Abl+ Cells Sensitive And Resistant To Sti571 Through Down-Regulation Mcl-1
  134. And Validation Of Mitochondria-Based Functional Assays To Investigate The Mechanism Of Small-Molecule Inhibitors Of Bcl-2/Bcl-Xl/Mcl-1 (Bh3 Mimetics) In Cell-Free …
  135. And Viscum Album Agglutinin-I-Induced Human Neutrophil Apoptosis: Viscum Album Agglutinin-I Accelerates The Loss Of Antiapoptotic Mcl-1 Expression And The …
  136. Androgenic Regulation Of The Anti-Apoptotic Bcl-2 Family Member Mcl-1 In Prostate Cancer Cells.
  137. Anisomycin Treatment Enhances Trail-Mediated Apoptosis In Renal Carcinoma Cells Through The Down-Regulation Of Bcl-2, C-Flip (L) And Mcl-1
  138. Annonaceous Acetogenin Mimic Aa005 Suppresses Human Colon Cancer Cell Growth In Vivo Through Downregulation Of Mcl-1
  139. Anoikis, Initiated By Mcl-1 Degradation And Bim Induction, Is Deregulated During Oncogenesis
  140. Antagonism Between Mcl-1 And Puma Governs Stem/Progenitor Cell Survival During Hematopoietic Recovery From Stress
  141. Anti-Apoptosis Proteins Mcl-1 And Bcl-Xl Have Different P53-Binding Profiles
  142. Antiapoptotic Action Of 1, 25-Dihydroxyvitamin D3Is Associated With Increased Mitochondrial Mcl-1 And Raf-1 Proteins And Reduced Release Of Cytochrome C
  143. Anti-Apoptotic Activity And Proteasome-Mediated Degradation Of Xenopus Mcl-1 Protein In Egg Extracts
  144. Anti-Apoptotic Bcl-2 Family Member Mcl-1 Regulates Cell Viability And Bone-Resorbing Activity Of Osteoclasts
  145. Anti-Apoptotic Bcl-X L But Not Mcl-1 Contributes To Protection Against Virus-Induced Apoptosis
  146. Antiapoptotic Effect Of C-Jun N-Terminal Kinase-1 Through Mcl-1 Stabilization In Tnf-Induced Hepatocyte Apoptosis
  147. Anti-Apoptotic Effects Of Osteopontin Through The Up-Regulation Of Mcl-1 In Gastrointestinal Stromal Tumors
  148. Anti-Apoptotic Functions Of Bcl-W, Mcl-1, And A1 In Mitotic Cell Death
  149. Antiapoptotic Mcl-1 Is Critical For The Survival And Niche-Filling Capacity Of Foxp3+ Regulatory T Cells
  150. Anti-Apoptotic Mcl-1 Is Essential For The Development And Sustained Growth Of Acute Myeloid Leukemia
  151. Anti-Apoptotic Mcl-1 Localizes To The Mitochondrial Matrix And Couples Mitochondrial Fusion To Respiration
  152. Anti-Apoptotic Mcl-1 Plays A Critical Role In Maintenance Of Normal And Malignant Human Hematopoietic Stem Cells Through Flt3 Signaling.
  153. Anti-Apoptotic Proteins Bcl-2, Mcl-1 And A1 Summate Collectively To Maintain Survival Of Immune Cell Populations Both In Vitro And In Vivo
  154. Antiapoptotic Proteins Mcl-1 And Bcl-2 As Well As Growth Factors Fgf And Vegf Influence Survival Of Peripheral Blood And Bone Marrow Chronic …
  155. Antibody Fragments Structurally Enable A Drug-Discovery Campaign On The Cancer Target Mcl-1
  156. Anticancer Activity Of Curcumin On Human Breast Adenocarcinoma: Role Of Mcl-1 Gene
  157. Anticancer Bioactive Peptides Suppress Human Colorectal Tumor Cell Growth And Induce Apoptosis Via Modulating The Parp-P53-Mcl-1 Signaling Pathway
  158. Anti-E6/E7/Mcl-1 Pegylated Lipoplexes For A Vaginal Treatment Of Cervical Cancer
  159. Antigen-Affinity Controls Pre-Germinal Center B Cell Selection By Promoting Mcl-1 Induction Through Baff Receptor Signaling
  160. Anti-Myeloma Effect Of Homoharringtonine With Concomitant Targeting Of The Myeloma-Promoting Molecules, Mcl-1, Xiap, And Β-Catenin
  161. Antimyeloma Effect Of The Simultaneous Inhibition Of Mcl-1 (With S63845) And Bcl-2 (With Venetoclax) In The Presence Of The Microenvironment
  162. Antioxidant Inhibition Of Gsk-3Β Stabilizes Anti-Apoptotic Factor Mcl-1 Leading To Decreased Apoptosis And Increased Cell Survival.
  163. Antisense Oligonucleotides Against Mcl-1 Result In Increased Apoptosis Of Human Neutrophils
  164. Antisense Strategy Shows That Mcl-1 Rather Than Bcl-2 Or Bcl-Xl Is An Essential Survival Protein Of Human Myeloma Cells
  165. Antisense Targeting Of Mcl-1 Has Therapeutic Potential In Gastric Cancer
  166. Anti-Survival And Pro-Apoptotic Effects On Hacat Human Keratinocytes Via Caspase-And Pkc-Dependent Downregulation Of Pkb, Hiap-1, Mcl-1, Xiap And Er …
  167. Anti-Tubulin Antibody Drug Conjugates Potentiate Venetoclax Activity In Non-Hodgkin Lymphoma By Targeting Mcl-1
  168. Antitumor Activity Of Fl118, A Survivin, Mcl-1, Xiap, And Ciap2 Selective Inhibitor, Is Highly Dependent On Its Primary Structure And Steric Configuration
  169. Apigenin Induces Apoptosis By Suppressing Bcl-Xl And Mcl-1 Simultaneously Via Signal Transducer And Activator Of Transcription 3 Signaling In Colon Cancer
  170. Apog2 Inhibits The Antiapoptotic Protein, Mcl‑1, And Induces Mitochondria‑Dependent Apoptosis In Human Colorectal Cancer Cells
  171. Apogossypol Derivative Bi-97C1 (Sabutoclax) Targeting Mcl-1 Sensitizes Prostate Cancer Cells To Mda-7/Il-24–Mediated Toxicity
  172. Apoptosis And Bax, Bcl-2, Mcl-1 Expression In Neutrophils Of Crohn’S Disease Patients
  173. Apoptosis And Expression Of Apoptosis Regulating Proteins Bcl-2, Mcl-1, Bcl-X, And Bax In Malignant Mesothelioma
  174. Apoptosis By Il-2 Deprivation In Human Cd8+ T Cell Blasts Predominates Over Death Receptor Ligation, Requires Bim Expression And Is Associated With Mcl-1 Loss
  175. Apoptosis In Gallbladder Carcinomas And Dysplasias, Its Relation To The Expression Of Caspases 3, 6 And 8 And Apoptosis Regulating Proteins Bcl-2, Mcl-1 And Bax
  176. Apoptosis In P53 Protein-Deficient Cells Is Mediated By Bh3-Only Protein-Independent Derepression Of Bak Protein Through Down-Regulation Of Mcl-1 And Bcl-Xl …
  177. Apoptosis Induced By 9, 11‑Dehydroergosterol Peroxide From Ganoderma Lucidum Mycelium In Human Malignant Melanoma Cells Is Mcl‑1 Dependent
  178. Apoptosis Induced By Ginkgo Biloba (Egb761) In Melanoma Cells Is Mcl-1-Dependent
  179. Apoptosis Induced By Overall Metabolic Stress Converges On The Bcl-2 Family Proteins Noxa And Mcl-1
  180. Apoptosis Induced By The Kinase Inhibitor Bay 43-9006 In Human Leukemia Cells Involves Down-Regulation Of Mcl-1 Through Inhibition Of Translation
  181. Apoptosis Induction In Human Melanoma Cells By Inhibition Of Mek Is Caspase-Independent And Mediated By The Bcl-2 Family Members Puma, Bim, And Mcl-1
  182. Apoptosis Involving The Inhibition Of Rna Polymerase Ii Carboxyl-Terminal Domain Phosphorylation And The Loss Of The Anti-Apoptotic Bcl2 Family Member Mcl-1.
  183. Apoptosis Is Rapidly Triggered By Antisense Depletion Of Mcl-1 In Differentiating U937 Cells
  184. Apoptosis Protection By Mcl-1 And Bcl-2 Modulation Of Inositol 1, 4, 5-Trisphosphate Receptor-Dependent Ca2+ Signaling
  185. Apoptosis Threshold Set By Noxa And Mcl-1 After T Cell Activation Regulates Competitive Selection Of High-Affinity Clones
  186. Apoptosis Threshold Set By Noxa And Mcl-1 Regulates Competitive Selection Of T Cell Clones
  187. Apoptosis Through Regulation Of Bcl-2, Bax And Mcl-1 Expressions In Endometriotic Cyst Lesions And The Endometrium Of Women With Moderate To Severe Endometriosis
  188. Apoptotic Effect Of Galbanic Acid Via Activation Of Caspases And Inhibition Of Mcl‐1 In H460 Non‐Small Lung Carcinoma Cells
  189. Apoptotic Index And Apoptosis Influencing Proteins Bcl‐2, Mcl‐1, Bax And Caspases 3, 6 And 8 In Pancreatic Carcinoma
  190. Apoptotic Regulation By Mcl-1 Through Heterodimerization
  191. Apoptotic Resistance Of Human Skin Mast Cells Is Mediated By Mcl-1
  192. Arsenic In The Shallow Ground Waters Of Conterminous United States: Assessment, Health Risks, And Costs For Mcl Compliance1
  193. Arsenic Trioxide Plus Abt-737 Is Synergistic To Induce Apoptosis In Aml Cells By Repression Of Mcl-1 Protein And Inactivation Of Bcl-2 Protein
  194. Arylazopyrazole Aap 1742 Inhibits Cdk S And Induces Apoptosis In Multiple Myeloma Cells Via Mcl‐1 Downregulation
  195. Aspirin Induces Apoptosis In Human Leukemia Cells Independently Of Nf-Κb And Mapks Through Alteration Of The Mcl-1/Noxa Balance
  196. Aspirin Induces Apoptosis In Human Leukemia Cells Independently Of Nf-Κb And Mapks Through Alteration Of The Mcl-1/Noxa Balance.
  197. Aspirin Induces Apoptosis In Yd-8 Human Oral Squamous Carcinoma Cells Through Activation Of Caspases, Down-Regulation Of Mcl-1, And Inactivation Of Erk-1/2 And …
  198. Aspirin Overcomes Navitoclax-Resistance In Hepatocellular Carcinoma Cells Through Suppression Of Mcl-1
  199. Assessment Of Bcl-2, Bcl-Xl And Mcl-1 In Bone Marrow Biopsy Samples Using Ventana Benchmark Xt Automated Slide Stainer
  200. Association Of Expression Of Mcl-1 And Puma Gene In Cervical Carcinomas [J]
  201. Association Of High-Level Mcl-1 Expression With In Vitro And In Vivo Prednisone Resistance In Mll-Rearranged Infant Acute Lymphoblastic Leukemia
  202. At-101 (-/-Gossypol) In Combination With Trastuzumab Triggers Apoptosis Through Inhibiting Bcl-2, Bcl-Xl And Mcl-1 Protein Levels In …
  203. At‐101 Downregulates Bcl 2 And Mcl 1 And Potentiates The Cytotoxic Effects Of Lenalidomide And Dexamethasone In Preclinical Models Of Multiple Myeloma And W …
  204. At-101 Induces Apoptosis In Cll B Cells And Overcomes Stromal Cell–Mediated Mcl-1 Induction And Drug Resistance
  205. Atm-Dependent Expression Of Iex-1 Controls Nuclear Accumulation Of Mcl-1 And The Dna Damage Response
  206. Attacking Oncogene Addiction In B-Cll: Seliciclib First Engages The Mcl-1/Noxa Axis, After Which Gradual Exhaustion Of Bcl-2 Protection Leads To Bax Activation.
  207. Atypical Apc/C‐Dependent Degradation Of Mcl‐1 Provides An Apoptotic Timer During Mitotic Arrest
  208. Aurora A And Mcl-1: New Potential Treatment Targets In Antiestrogen-Resistant Breast Cancer
  209. Autophagy-Mediated Hmgb1 Release Antagonizes Apoptosis Of Gastric Cancer Cells Induced By Vincristine Via Transcriptional Regulation Of Mcl-1
  210. Azd4573 Is A Highly Selective Cdk9 Inhibitor That Suppresses Mcl-1 And Induces Apoptosis In Hematological Cancer Cells.
  211. Aβ Activation Of Sgk1 And Increase In Mcl‐1 Expression Protects Against Aβ‐Induced Toxicity In Pc12 Cells
  212. -B]Pyrrole-9-Carbonitrile (S1) Based Molecules As Potent, Dual Inhibitors Of B-Cell Lymphoma 2 (Bcl-2) And Myeloid Cell Leukemia Sequence 1 (Mcl-1): Structure-Based Design …
  213. Bad And Mcl-1 Regulation In Prostate Cancer
  214. Bad Dephosphorylation And Decreased Expression Of Mcl-1 Induce Rapid Apoptosis In Prostate Cancer Cells
  215. Bag3 Upregulates Mcl-1 Through Downregulation Of Mir-29B To Induce Anticancer Drug Resistance In Ovarian Cancer
  216. Bag3‐Dependent Expression Of Mcl‐1 Confers Resistance Of Mutant Kras Colon Cancer Cells To The Hsp90 Inhibitor Auy922
  217. Bag3-Dependent Expression Of Mcl-1 Confers Resistance Of Mutant Kras Colon Cancer Cells To The Hsp90 Inhibitor Auy922” Published In …
  218. Bag3-Mediated Mcl-1 Stabilization Contributes To Drug Resistance Via Interaction With Usp9X In Ovarian Cancer
  219. Baicalein, A Component Of Scutellaria Baicalensis, Induces Apoptosis By Mcl-1 Down-Regulation In Human Pancreatic Cancer Cells
  220. Bak And Mcl-1 Are Essential For Temozolomide Induced Cell Death In Human Glioma
  221. Bak Binding To Bcl-Xl And Not To Mcl-1 Is Associated With Abt-737 Sensitivity In Multiple Myeloma Cell Lines
  222. Barr Virus Latent Membrane Protein-1 Protects B-Cell Lymphoma From Rituximab-Induced Apoptosis Through Mir-155-Mediated Akt Activation And Up-Regulation Of Mcl-1
  223. Bax/Mcl-1 Balance Affects Neutrophil Survival In Intermittent Hypoxia And Obstructive Sleep Apnea: Effects Of P38Mapk And Erk1/2 Signaling
  224. Bax-Bak Heterodimer As A Pharmacodynamic Biomarker Of On-Target Drug Action Of Mcl-1 Inhibitors To Evaluate In-Vivo Effectiveness.
  225. Bay 61-3606 Sensitizes Trail-Induced Apoptosis By Downregulating Mcl-1 In Breast Cancer Cells
  226. Bcl-2 And Mcl-1 Expression In Chinese Hamster Ovary Cells Inhibits Intracellular Acidification And Apoptosis Induced By Staurosporine
  227. Bcl-2 Family Member Mcl-1 Expression Is Reduced Under Hypoxia By The E3 Ligase Fbw7 Contributing To Bnip3 Induced Cell Death In Glioma Cells
  228. Bcl-2 Family Members Puma, Noxa And Mcl-1, In P53 Mediated Neuronal Cell Death
  229. Bcl-2 Family Proteins In Breast Development And Cancer: Could Mcl-1 Targeting Overcome Therapeutic Resistance?
  230. Bcl-2 Is A Better Abt-737 Target Than Bcl-Xl Or Bcl-W And Only Noxa Overcomes Resistance Mediated By Mcl-1, Bfl-1, Or Bcl-B
  231. Bcl-2, Mcl-1 And P53 Expression Confer Sensitivity To Bcl-2 Inhibitor Abt-737 In Multiple Myeloma.
  232. Bcl-Xl And Mcl-1 Are Involved In Prevention Of In Vitro Apoptosis In Rat Late-Stage Erythroblasts Derived From Bone Marrow
  233. Bcl-Xl And Mcl-1 Are The Key Bcl-2 Family Proteins In Melanoma Cell Survival
  234. Bcl-Xl And Mcl-1 Are The Major Determinants Of The Apoptotic Response To Dual Pi3K And Mek Blockage
  235. Bcl‐Xl And Mcl‐1 Constitute Pertinent Targets In Ovarian Carcinoma And Their Concomitant Inhibition Is Sufficient To Induce Apoptosis
  236. Bcl-Xl And Mcl-1 Upregulation By Calreticulin Promotes Apoptosis Resistance Of Fibroblast-Like Synoviocytes Via Activation Of Pi3K/Akt And Stat3 Pathways In …
  237. Bcl-Xl/Mcl-1 Inhibition And Rarγ Antagonism Work Cooperatively In Human Hl60 Leukemia Cells
  238. Bcr Signaling Inhibitors Differ In Their Ability To Overcome Mcl-1–Mediated Resistance Of Cll B Cells To Abt-199
  239. Bcr-Abl+ Bp-All Exhibits Heightened Sensitivity To Simultaneous Induction Of Energy And Er Stress Via Downregulation Of Mcl-1 Expression
  240. Beclin 1 Restrains Tumorigenesis Through Mcl-1 Destabilization In An Autophagy-Independent Reciprocal Manner
  241. Becn1 And Bim Interactions With Mcl-1 Determine Fludarabine Resistance In Leukemic B Cells
  242. Berberine Sensitizes Trail-Induced Apoptosis Through Proteasome-Mediated Downregulation Of C-Flip And Mcl-1 Proteins
  243. Betulinic Acid-Induced Mcl-1 Expression In Human Melanoma—Mode Of Action And Functional Significance
  244. Bfl-1/A1 Functions, Similar To Mcl-1, As A Selective Tbid And Bak Antagonist
  245. Bh3 Mimetic Abt-737 Sensitizes Colorectal Cancer Cells To Ixazomib Through Mcl-1 Downregulation And Autophagy Inhibition
  246. Bh3 Mimetic Obatoclax (Gx15-070) Mediates Mitochondrial Stress Predominantly Via Mcl-1 Inhibition And Induces Autophagy-Dependent Necroptosis In …
  247. Bh3‐Ligand Regulates Access Of Mcl‐1 To Its E3 Ligase
  248. Bh3-Only Proteins Are Dispensable For Apoptosis Induced By Pharmacological Inhibition Of Both Mcl-1 And Bcl-X L
  249. Bh3-Only Proteins In Control: Specificity Regulates Mcl-1 And Bak-Mediated Apoptosis
  250. Bh3-Only Proteins Mcl-1 And Bim As Well As Endonuclease G Are Targeted In Spongistatin 1–Induced Apoptosis In Breast Cancer Cells
  251. Bh3-Only Proteins Target Bcl-Xl/Mcl-1, Not Bax/Bak, To Initiate Apoptosis
  252. Bicyclic Helical Peptides As Dual Inhibitors Selective For Bcl2A1 And Mcl-1 Proteins
  253. Bicyclic Helical Peptides As Dual Inhibitors Selective For Bcl2A1 And Mcl‑1 Proteins
  254. Bile Acid-Induced “Minority Momp” Promotes Esophageal Carcinogenesis While Maintaining Apoptotic Resistance Via Mcl-1
  255. Bile Acid-Mediated Induction Of Cyclooxygenase-2 And Mcl-1 In Hepatic Stellate Cells
  256. Bile Acids Inhibit Mcl-1 Protein Turnover Via An Epidermal Growth Factor Receptor/Raf-1-Dependent Mechanism
  257. Bim And Mcl-1 Exert Key Roles In Regulating Jak2 V617F Cell Survival
  258. Bim Phosphorylation Enhances Its Pro-Apoptotic Activity Through Down-Regulation Of The Interaction With Mcl-1
  259. Bim Upregulation By Histone Deacetylase Inhibitors Mediates Interactions With The Bcl-2 Antagonist Abt-737: Evidence For Distinct Roles For Bcl-2, Bcl-Xl, And Mcl-1
  260. Binding Affinity Of Pro-Apoptotic Bh3 Peptides For The Anti-Apoptotic Mcl-1 And A1 Proteins: Molecular Dynamics Simulations Of Mcl-1 And A1 In Complex With Six …
  261. Binding Mode Of Pyridoclax To Myeloid Cell Leukemia-1 (Mcl-1) Revealed By Nuclear Magnetic Resonance Spectroscopy, Docking And Molecular Dynamics Approaches
  262. Binding Of Released Bim To Mcl-1 Is A Mechanism Of Intrinsic Resistance To Abt-199 Which Can Be Overcome By Combination With Daunorubicin Or Cytarabine In Aml …
  263. Binding Of Released Bim To Mcl-1 Is Responsible For Resistance To Abt-199 Which Can Be Overcome By Combination With Daunorubicin Or Cytarabine In Acute Myeloid …
  264. Biochemical And Functional Comparisons Of Mcl-1 And Bcl-2 Proteins: Evidence For A Novel Mechanism Of Regulating Bcl-2 Family Protein Function.
  265. Biphasic Onset Of Splenic Apoptosis Following Hemorrhagic Shock: Critical Implications For Bax, Bcl-2, And Mcl-1 Proteins
  266. Birc6 Mediates Imatinib Resistance Independently Of Mcl-1
  267. Bisindolylmaleimide Ix Is A Potent Inducer Of Apoptosis In Chronic Lymphocytic Leukaemic Cells And Activates Cleavage Of Mcl-1
  268. Blocks Tumor Growth, Angiogenesis, And Metastatic Potential In Preclinical Models Of Osteosarcoma Through The Inhibition Of Erk1/2, Mcl‐1, And Ezrin Pathways
  269. Bone Marrow Microenvironment–Derived Signals Induce Mcl-1 Dependence In Multiple Myeloma
  270. Bone Marrow Stroma-Induced Resistance Of Chronic Lymphocytic Leukemia Cells To Arsenic Trioxide Involves Mcl-1 Upregulation And Is Overcome By Inhibiting …
  271. Bone Marrow Stromal Cells Enforce Mcl-1 Dependence In Multiple Myeloma Through The Secretion Of A Soluble Factor
  272. Bortezomib Antagonizes Microtubule-Interfering Drug-Induced Apoptosis By Inhibiting G2/M Transition And Mcl-1 Degradation
  273. Bortezomib Sensitivity Of Acute Myeloid Leukemia Cd34+ Cells Can Be Enhanced By Targeting The Persisting Activity Of Nf-Κb And The Accumulation Of Mcl-1
  274. Bortezomib Sensitizes Human Glioblastoma Cells To Induction Of Apoptosis By Type I Interferons Through Noxa Expression And Mcl-1 Cleavage
  275. Bortezomib‐Induced Apoptosis In Mature T‐Cell Lymphoma Cells Partially Depends On Upregulation Of Noxa And Functional Repression Of Mcl‐1
  276. Braf/Mek Inhibitors Selectively Prime Melanoma For Mcl-1 Dependence And Sensitize To Mcl-1 Inhibition
  277. Brafv600E-Dependent Mcl-1 Stabilization Leads To Everolimus Resistance In Colon Cancer Cells
  278. Bryostatin Induces Protein Kinase C Modulation, Mcl-1 Up-Regulation And Phosphorylation Of Bcl-2 Resulting In Cellular Differentiation And Resistance To Drug-Induced …
  279. Bufadienolide Compounds Sensitize Human Breast Cancer Cells To Trail-Induced Apoptosis Via Inhibition Of Stat3/Mcl-1 Pathway
  280. Bufo Gargarizans Mcl-1 Cloning And Its Prokaryotic Recombinant Protein Expression
  281. By Reducing Global Mrna Translation In Several Ways, 2-Deoxyglucose Lowers Mcl-1 Protein And Sensitizes Hemopoietic Tumor Cells To Bh3 Mimetic Abt737
  282. Bz-423 Superoxide Signals B Cell Apoptosis Via Mcl-1, Bak, And Bax
  283. C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukaemia Cells
  284. C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukemia Cells
  285. Cafestol Overcomes Abt-737 Resistance In Mcl-1-Overexpressed Renal Carcinoma Caki Cells Through Downregulation Of Mcl-1 Expression And Upregulation Of …
  286. Caffeine Inhibits Paclitaxel‑Induced Apoptosis In Colorectal Cancer Cells Through The Upregulation Of Mcl‑1 Levels
  287. Caki Cells To Trail-Induced Apoptosis Through Reactive Oxygen Species-Mediated Inhibition Of Akt Signaling And Downregulation Of Mcl-1 And C-Flip (L)
  288. Calcium Signals Inhibition Sensitizes Ovarian Carcinoma Cells To Anti-Bcl-Xl Strategies Through Mcl-1 Down-Regulation
  289. Caloric Restriction Modulates Mcl-1 Expression And Sensitizes Lymphomas To Bh3 Mimetic In Mice
  290. Camptothecin And Khat (Catha Edulis Forsk.) Induced Distinct Cell Death Phenotypes Involving Modulation Of C-Flipl, Mcl-1, Procaspase-8 And Mitochondrial …
  291. Carcinoma Hep-G2 Cell Proliferation By Increasing Tnf-Α, Caspase-8, Caspase-3 And Bax But By Decreasing Tctp And Mcl-1 Expression In Vitro
  292. Cardiac Specific Deletion Of Mcl-1 Leads To Impaired Autophagy And Rapid Development Of Heart Failure
  293. Carfilzomib And Onx 0912 Inhibit Cell Survival And Tumor Growth Of Head And Neck Cancer And Their Activities Are Enhanced By Suppression Of Mcl-1 Or Autophagy
  294. Caspase Cleavage Of Mcl-1 Impairs Its Anti-Apoptotic Activity And Proteasomal Degradation In Non-Small Lung Cancer Cells
  295. Caspase-Dependent Mcl-1 Cleavage And Effect Of Mcl-1 Phosphorylation In Abt-737-Induced Apoptosis In Human Acute Lymphoblastic Leukemia Cell Lines
  296. Caspase-Dependent Post-Translational Modulation Of Mcl-1 By Abt-737 In Acute Lymphoblastic Cell Lines
  297. Caveolin-1 Regulates Mcl-1 Stability And Anoikis In Lung Carcinoma Cells
  298. Caveolin-1, Antiapoptosis Signaling, And Anchorage-Independent Cell Growth. Focus On “Caveolin-1 Regulates Mcl-1 Stability And Anoikis In Lung Carcinoma Cells”
  299. Cb-59. Bcl-2 Family Member Mcl-1 Regulates Hypoxia-Induced Cell Death Through Blocking Bh3-Only Member Bnip3 Function In …
  300. Cbio-10Bcl-2 Family Member Mcl-1 Expression Is Reduced Under Hypoxia By The E3 Ligase Fbw7 Contributing To Bnip3 Induced Cell …
  301. Cd44 Activation Enhances Acute Monoblastic Leukemia Cell Survival Via Mcl-1 Upregulation
  302. Cd44 Signaling Via Pi3K/Akt And Mapk/Erk Pathways Protects Cll Cells From Spontaneous And Drug Induced Apoptosis Through Mcl-1
  303. Cdk Inhibitors Roscovitine And Cr8 Trigger Mcl-1 Down-Regulation And Apoptotic Cell Death In Neuroblastoma Cells
  304. Cdk1/Cyclin B Plays A Key Role In Mitotic Arrest-Induced Apoptosis By Phosphorylation Of Mcl-1, Promoting Its Degradation And Freeing Bak From Sequestration
  305. Cdk5 Inhibitor Downregulates Mcl-1 And Sensitizes Pancreatic Cancer Cell Lines To Navitoclax
  306. Cdk9 Inhibition By Dinaciclib Potently Suppresses Mcl-1 To Induce Durable Apoptotic Responses In Aggressive Myc-Driven B-Cell Lymphoma In Vivo
  307. Cdk9 Inhibition Reverses Resistance To Abt-199 (Gdc-0199) By Down-Regulating Mcl-1
  308. Cdk9 Inhibitors Selectively Target Estrogen Receptor-Positive Breast Cancer Cells Through Combined Inhibition Of Myb And Mcl-1 Expression
  309. Cell Penetrating Proteins Targeting Mcl-1 Induce In Vitro And In Vivo On-Target Cancer Cell Killing Of Mcl-1 Dependent Cell Lines
  310. Cells To Vorinostat‐Induced Apoptosis Depends On Reactive Oxygen Species Production, Mitochondrial Dysfunction, Noxa Upregulation, Mcl‐1 Cleavage, And Dna …
  311. Ceramide Analogue Saclac Modulates Sphingolipid Levels And Mcl-1 Splicing To Induce Apoptosis In Acute Myeloid Leukemia
  312. C-Flip And The Noxa/Mcl-1 Axis Participate In The Synergistic Effect Of Pemetrexed Plus Cisplatin In Human Choroidal Melanoma Cells
  313. Changes In Mcl-1 And Bim Expression With Bortezomib And Melphalan Therapy For Multiple Myeloma.
  314. Changes In Mcl-1 Expression In Rectal Cancer In Relation To Neo-Adjuvant Radiotherapy
  315. Characterisation Of Mcl‐1 Cleavage During Apoptosis Of Haematopoietic Cells
  316. Characterization And Development Of On-Target Mcl-1 Inhibitors; Bh3 Profiling Provides A Valuable Drug Discovery Tool.
  317. Characterization And Expression Analyses Of Anti-Apoptotic Bcl-2-Like Genes Nr-13, Mcl-1, Bcl-X1, And Bcl-X2 In Atlantic Cod (Gadus Morhua)
  318. Characterization Of Mcl-1 Isoforms And Their Impacts On Mammalian Cell Growth
  319. Characterization Of Pyoluteorin Derivatives As Mcl-1 Antagonists
  320. Characterization Of The Antiapoptotic Bcl-2 Family Member Myeloid Cell Leukemia-1 (Mcl-1) And The Stimulation Of Its Message By Gonadotropins In The Rat Ovary
  321. Characterizaton Of Mcl-1 In Regulating Different Forms Of Cell Death
  322. Chemical Perturbation Of Mcl-1 Pre-Mrna Splicing To Induce Apoptosis In Cancer Cells
  323. Chemotherapeutic Drugs Sensitize Human Renal Cell Carcinoma Cells To Abt-737 By A Mechanism Involving The Noxa-Dependent Inactivation Of Mcl-1 Or A1
  324. Chidamide Inhibits Aerobic Metabolism To Induce Pancreatic Cancer Cell Growth Arrest By Promoting Mcl-1 Degradation
  325. Chlamydia Trachomatis Can Protect Host Cells Against Apoptosis In The Absence Of Cellular Inhibitor Of Apoptosis Proteins And Mcl-1
  326. Chlamydia Trachomatis-Containing Vacuole Serves As Deubiquitination Platform To Stabilize Mcl-1 And To Interfere With Host Defense
  327. Chloroplumbagin Induces Cell Death In Breast Cancer Cells Through Mapk-Mediated Mcl-1 Inhibition
  328. Chloroquine Induces Apoptosis Of Human Hepatocellular Carcinoma Cells In Vitro By Mir-26B-Mediated Regulation Of Mcl-1
  329. Chop Treatment Enhances Dependency On Bcl-2, Mcl-1 And Bcl-Xl In Diffuse Large B-Cell Lymphoma: Pf521
  330. Chromatin Remodeling At Alu Repeats By Epigenetic Treatment Activates Silenced Microrna-512-5P With Downregulation Of Mcl-1 In Human Gastric Cancer Cells
  331. Chrysin Overcomes Trail Resistance Of Cancer Cells Through Mcl-1 Downregulation By Inhibiting Stat3 Phosphorylation
  332. Circular Rna Circ_0067934 Functions As An Oncogene In Breast Cancer By Targeting Mcl-1
  333. Circumvention Of Mcl-1-Dependent Drug Resistance By Simultaneous Chk1 And Mek1/2 Inhibition In Human Multiple Myeloma Cells
  334. Cleavage Of Mcl-1 By Caspases Impaired Its Ability To Counteract Bim-Induced Apoptosis
  335. Clinical Significance And Expression Of Puma, Mcl-1, And P53 In Human Renal Cell Carcinoma And Para-Carcinoma Tissues
  336. Clitocine Induces Apoptosis And Enhances The Lethality Of Abt-737 In Human Colon Cancer Cells By Disrupting The Interaction Of Mcl-1 And Bak
  337. Clitocine Potentiates Trail-Mediated Apoptosis In Human Colon Cancer Cells By Promoting Mcl-1 Degradation
  338. Clitocine Targets Mcl-1 To Induce Drug-Resistant Human Cancer Cell Apoptosis In Vitro And Tumor Growth Inhibition In Vivo
  339. Cloning And Bioinformatics Analysis Of Mcl-1 Cdna Of Bufo Japonicus Formosus [J]
  340. Cloning And Characterization Of Cdna Encoding The Porcine Mcl-1 Protein
  341. C-Myc Dependent Expression Of Pro-Apoptotic Bim Renders Her2-Overexpressing Breast Cancer Cells Dependent On Anti-Apoptotic Mcl-1
  342. Co-Delivery Of Gemcitabine And Mcl-1 Sirna Via Cationic Liposome-Based System Enhances The Efficacy Of Chemotherapy In Pancreatic Cancer
  343. Co-Inhibition Of Bcl-Xl And Mcl-1 With Bcl-2 Selective Inhibitors A1331852 And S63845 Enhances Cytotoxicity Of Cervical Cancer Cell Lines
  344. Colorectal Cancer Cell Lines With High Bcl-Xl And Low Mcl-1 Expression Are Sensitive To A Potent And Selective Bcl-Xl Inhibitor
  345. Combination Of Hypoglycemia And Metformin Impairs Tumor Metabolic Plasticity And Growth By Modulating The Pp2A-Gsk3Β-Mcl-1 Axis
  346. Combination Treatment Of Rad001 And Bez235 Exhibits Synergistic Antitumor Activity Via Down-Regulation Of P-4E-Bp1/Mcl-1 In Small Cell Lung Cancer
  347. Combined Inhibition Of Bcl-2 And Mcl-1 In Small Cell Lung Cancer (Sclc) Is Most Effective In Tumors With Low Bcl-Xl Expression
  348. Combined Inhibition Of Rac1 And Bcl-2/Bcl-Xl Synergistically Induces Glioblastoma Cell Death Through Down-Regulation Of The Usp9X/Mcl-1 Axis
  349. Combined Inhibition Of The Pi3K/Mtor/Mek Pathway Induces Bim/Mcl-1-Regulated Apoptosis In Pancreatic Cancer Cells
  350. Combined Targeting Of Mcl-1 With Tg02 And Bcl-2 With Abt-199/Abt-737 For Treatment Of Hematologic Malignancies
  351. Combined Targeting Of Mek And Mcl-1 Induces Apoptosis And Tumor Regression Of Kras Mutant Nsclc
  352. Comparison Of Umbelliprenin And Auraptene In Cytotoxic Effects And Myeloid Cell Leukemia Type-1 (Mcl-1) Gene Expression
  353. Compound C Sensitizes Caki Renal Cancer Cells To Trail-Induced Apoptosis Through Reactive Oxygen Species-Mediated Down-Regulation Of C-Flipl And Mcl-1
  354. Computer-Aided Drug Design Of Neuraminidase Inhibitors And Mcl-1 Specific Drugs
  355. Concomitant Targeting Of Hedgehog Signaling And Mcl-1 Synergistically Induces Cell Death In Hedgehog-Driven Cancer Cells
  356. Concurrent Inhibition Of Pi3K And Mtorc1/Mtorc2 Overcomes Resistance To Rapamycin Induced Apoptosis By Down‐Regulation Of Mcl‐1 In Mantle Cell Lymphoma
  357. Concurrent Inhibition Of Pi3-Kinase And Mtor Induces Cell Death In Diffuse Large B Cell Lymphomas, A Mechanism Involving Down Regulation Of Mcl-1
  358. Concurrent Inhibition Of Pim And Flt3 Kinases Enhances Apoptosis Of Flt3-Itd Acute Myeloid Leukemia Cells Through Increased Mcl-1 Proteasomal Degradation
  359. Constitutively Activated Akt-1 Is Vital For The Survival Of Human Monocyte-Differentiated Macrophages: Role Of Mcl-1, Independent Of Nuclear Factor (Nf)-Κb, Bad, Or …
  360. Construction Of Recombinant Plasmids Containing Shrna Targeting Mcl-1 Gene And Its Effect On Proliferation And Apoptosis Of Hepg2 Cells
  361. Contrasting Effects Of Nutlin-3 On Trail-And Docetaxel-Induced Apoptosis Due To Upregulation Of Trail-R2 And Mcl-1 In Human Melanoma Cells
  362. Cooperative Anti-Leukemic Effects Of Imatinib And Mcl-1 Antisense: Identification Of Mcl-1 As A Novel Target In Cml.
  363. Cooperative Regulation Of Mcl-1 By Janus Kinase/Stat And Phosphatidylinositol 3-Kinase Contribute To Granulocyte-Macrophage Colony-Stimulating Factor-Delayed …
  364. Correction To “Structure Based Design Of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors”
  365. Correction To: A Novel Histone Deacetylase Inhibitor, Cg200745, Potentiates Anticancer Effect Of Docetaxel In Prostate Cancer Via Decreasing Mcl-1 And Bcl-Xl.
  366. Correction: The Multikinase Inhibitor Sorafenib Potentiates Trail Lethality In Human Leukemia Cells In Association With Mcl-1 And Cflipl Down-Regulation
  367. Correlation Between Mcl-1 And Pakt Protein Expression In Colorectal Cancer
  368. Cover Picture: Deactivation Of Mcl‐1 By Dual‐Function Small‐Molecule Inhibitors Targeting The Bcl‐2 Homology 3 Domain And Facilitating Mcl‐1 Ubiquitination …
  369. Coxiella Burnetii Inhibits Neutrophil Apoptosis By Exploiting Survival Pathways And Antiapoptotic Protein Mcl-1
  370. Critical B-Lymphoid Cell Intrinsic Role Of Endogenous Mcl-1 In C-Myc-Induced Lymphomagenesis
  371. Critical Contribution Of Mcl-1 In Emt-Associated Chemo-Resistance In A549 Non-Small Cell Lung Cancer
  372. Critical Role For Antiapoptotic Bcl-Xl And Mcl-1 In Human Macrophage Survival And Cellular Iap1/2 (Ciap1/2) In Resistance To Hiv-Vpr-Induced Apoptosis
  373. Critical Roles Of Noxa And Mcl-1 In The Signaling Mechanisms Of Bortezomib In Traf3-Deficient Mouse B Lymphoma And Human Multiple Myeloma Cells
  374. Crosstalk Among Bcl-2 Family Members In B-Cll: Seliciclib Acts Via The Mcl-1/Noxa Axis And Gradual Exhaustion Of Bcl-2 Protection
  375. Cryptosphaerolide, A Cytotoxic Mcl-1 Inhibitor From A Marine-Derived Ascomycete Related To The Genus Cryptosphaeria
  376. Culmination Of Mg132-Induced Apoptosis In Human Lung Cancer Nci-H1703 Cells Depends On A Positive Feedback Of Caspase Activation And Mcl-1 Cleavage
  377. Curcumin Induces Apoptosis And Inhibits Proliferation In Infantile Hemangioma Endothelial Cells Via Downregulation Of Mcl-1 And Hif-1Α
  378. Current And Emerging Therapies For Patients With Acute Myeloid Leukemia: A Focus On Mcl-1 And The Cdk9 Pathway.
  379. Cyc202 (R-Roscovitine) Induces Apoptosis In Multiple Myeloma Cells By Down Regulation Of Mcl-1
  380. Cyclic Amp Delays Neutrophil Apoptosis Via Stabilization Of Mcl-1
  381. Cyclic Marinopyrrole Derivatives As Disruptors Of Mcl-1 And Bcl-Xl Binding To Bim
  382. Cyclin E But Not Bcl-2, Bax Or Mcl-1 Is Differentially Expressed In Zap 70-Positive And Zap 70-Negative B-Cll Cells
  383. Cyclin E/Cdk2-Dependent Phosphorylation Of Mcl-1 Determines Its Stability And Cellular Sensitivity To Bh3 Mimetics
  384. Cyclin E1 Inhibition Can Overcome Sorafenib Resistance In Hepatocellular Carcinoma Cells Through Mcl-1 Suppression
  385. Cyclin-Dependent Kinase Inhibitor Drugs Drive Neutrophil Granulocyte Apoptosis By Transcriptional Inhibition Of The Key Survival Protein Mcl-1
  386. Cyclocommunol Induces Apoptosis In Human Oral Squamous Cell Carcinoma Partially Through A Mcl-1-Dependent Mechanism
  387. Cyclooxygenase-2 Inducing Mcl-1-Dependent Survival Mechanism In Human Lung Adenocarcinoma Cl1. 0 Cells Involvement Of Phosphatidylinositol 3 …
  388. Cytokine-Dependent And Cytokine-Independent Roles For Mcl-1: Genetic Evidence For Multiple Mechanisms By Which Mcl-1 Promotes Survival In Primary T …
  389. Cytotoxicity Induced By Manipulation Of Signal Transduction Pathways Is Associated With Down-Regulation Of Bcl-2 But Not Mcl-1 In Mcf-7 Human Breast Cancer
  390. De Novo Design, Synthesis And Evaluation Of Benzylpiperazine Derivatives As Highly Selective Binders Of Mcl‐1
  391. Deactivation Of Mcl‐1 By Dual‐Function Small‐Molecule Inhibitors Targeting The Bcl‐2 Homology 3 Domain And Facilitating Mcl‐1 Ubiquitination
  392. Death Of Multiple Myeloma Cells Induced By Camp-Signaling Involves Downregulation Of Mcl-1 Via The Jak/Stat Pathway
  393. Decreased Mcl-1 Protein Level In The Striatum Of 1-Methyl-4-Phenyl-1, 2, 3, 6-Tetrahydropyridine (Mptp)-Treated Mice
  394. Degradation Of Mcl-1 By Bufalin Reverses Acquired Resistance To Osimertinib In Egfr-Mutant Lung Cancer
  395. Degradation Of Mcl-1 By Granzyme B Implications For Bim-Mediated Mitochondrial Apoptotic Events
  396. Degradation Of Mcl-1 By Β-Trcp Mediates Glycogen Synthase Kinase 3-Induced Tumor Suppression And Chemosensitization
  397. Degradation Of Mcl-1 Through Gsk-3Β Activation Regulates Apoptosis Induced By Bufalin In Non-Small Cell Lung Cancer H1975 Cells
  398. Delayed Apoptosis By Neutrophils From Copd Patients Is Associated With Altered Bak, Bcl-Xl, And Mcl-1 Mrna Expression
  399. Deleting Mcl-1 In Mast Cells: Getting 2 Birds With 1 Stone
  400. Deletion Of Mcl-1 Causes Lethal Cardiac Failure And Mitochondrial Dysfunction
  401. Deletion Of Mir155 Prevents Fas-Induced Liver Injury Through Up-Regulation Of Mcl-1
  402. Demethoxy-Reblastatin, An Hsp90 Inhibitor, Induces Mitochondria-Mediated Apoptosis Through Downregulation Of Mcl-1 In Human Hepatocellular Carcinoma Cells
  403. Deregulated Expression Of A1, Bcl-2, Bcl-Xl, And Mcl-1 Antiapoptotic Proteins And Bid, Bad, And Bax Proapoptotic Genes In Polycythemia Vera Patients
  404. Design, Synthesis And Biological Evaluation Of Two Chemical Classes As Novel Small Molecule Mcl-1 Inhibitors
  405. Design, Synthesis And Evaluation Of Marinopyrrole Derivatives As Selective Inhibitors Of Mcl-1 Binding To Pro-Apoptotic Bim And Dual Mcl-1/Bcl-Xl Inhibitors
  406. Design, Synthesis And Preliminary Bioactivity Studies Of Indomethacin Derivatives As Bcl-2/Mcl-1 Dual Inhibitors
  407. Design, Synthesis And Preliminary Biological Evaluation Of Indole-3-Carboxylic Acid-Based Skeleton Of Bcl-2/Mcl-1 Dual Inhibitors
  408. Design, Synthesis And Preliminary Biological Studies Of Pyrrolidine Derivatives As Mcl-1 Inhibitors
  409. Design, Synthesis And Structure–Activity Relationship Studies Of Morpholino-1H-Phenalene Derivatives That Antagonize Mcl-1/Bcl-2
  410. Designed Bh3 Peptides With High Affinity And Specificity For Targeting Mcl-1 In Cells
  411. Designing Of De Novo Dual Inhibitors For Bcl-Xl And Mcl-1 Of Bcl2-Family Proteins By Computational Methods
  412. Detection Of Bcl-2 In Kaposi’S Sarcoma Lesions Varies According To Histopathologic Stage, Whereas Expression Of Bcl-X And Mcl-1 Differs According To Human …
  413. Determinants Of Bh3 Binding Specificity For Mcl-1 Versus Bcl-Xl
  414. Deubiquitinase Usp9X Confers Radioresistance Through Stabilization Of Mcl-1
  415. Deubiquitylating Enzyme Usp9X Regulates Radiosensitivity In Glioblastoma Cells By Mcl-1-Dependent And-Independent Mechanisms
  416. Development And Characterization Of Novel Mcl-1 Inhibitors For Treatment Of Cancer.
  417. Development And Maintenance Of B And T Lymphocytes Requires Antiapoptotic Mcl-1
  418. Development Of An Efficient Route Toward Meiogynin A-Derived Dual Inhibitors Of Bcl-Xl And Mcl-1 Anti-Apoptotic Proteins
  419. Development Of An Efficient Route Toward Meiogynin A-Inspired Dual Inhibitors Of Bcl-Xl And Mcl-1 Anti-Apoptotic Proteins
  420. Development Of Novel Dual Inhibitor Of Chemokine Receptor 4 And Mcl-1 Against Multiple Myeloma
  421. Development Of Small Molecule Inhibitors Of Mcl-1 For Cancer Therapy
  422. Dexamethasone Synergizes With Mcl-1 Inhibition In Multiple Myeloma Through Suppression Of S6 Phosphorylation
  423. Dicoumarol Sensitizes Renal Cell Carcinoma Caki Cells To Trail-Induced Apoptosis Through Down-Regulation Of Bcl-2, Mcl-1 And C-Flip In A Nqo1-Independent Manner
  424. Differences In Dna Binding Properties Between E2F1 And E2F4 Specify Repression Of The Mcl-1 Promoter
  425. Differences In Trail-Induced Changes Of Mcl-1 Expression Among Distinct Human Colon Epithelial Cell Lines
  426. Differential Binding Affinities Of Anti-Apoptotic Mcl-1 And A1 Proteins For The Pro-Apoptotic Bh3 Peptides: Understanding The Molecular Basis Using Md …
  427. Differential Effects Of Aging On Mcl-1 And Caspase 3 Expression In Murine Small And Large Intestine
  428. Differential Effects Of Anti-Apoptotic Bcl-2 Family Members Mcl-1, Bcl-2, And Bcl-Xl On Celecoxib-Induced Apoptosis
  429. Differential Gadd45, P21C1P1/Waf1, Mcl-1 And Topoisomerase Ii Gene Induction And Secondary Dna Fragmentation After Camptothecin-Induced Dna Damage In …
  430. Differential Mcl-1 Processing In Evasion Of Dca-Induced Apoptosis Of Colorectal Cancer Cells.
  431. Differential Noxa/Mcl-1 Balance In Peripheral Versus Lymph Node Chronic Lymphocytic Leukemia Cells Correlates With Survival Capacity
  432. Differential Regulation Of Bax And Bak By Anti-Apoptotic Bcl-2 Family Proteins Bcl-B And Mcl-1
  433. Differential Regulations And Roles Of Mcl-1 And Bcl-Xl During Megakaryopoiesis
  434. Differential Regulations And Roles Of Mcl-1 And Bcl-Xl During Megakaryopoiesis (초)
  435. Differential Responses Of Mcl-1 In Photosensitized Epithelial Vs Lymphoid-Derived Human Cancer Cells
  436. Dihydroartemisinin Suppresses Stat3 Signaling And Mcl-1 And Survivin Expression To Potentiate Abt-263-Induced Apoptosis In Non-Small Cell Lung Cancer Cells …
  437. Diminishing Mcl-1 Protein Leads To Apoptosis Of Acute Myeloid Leukemia Cells Responding To All Trans Retinoic Acid Differentiation
  438. Dinaciclib Potently Suppresses Mcl-1 And Selectively Induces The Cell Death In Human Ips Cells Without Affecting The Viability Of Cardiac Tissue
  439. Dinaciclib, A Cdk Inhibitor Promotes Proteasomal Degradation Of Mcl-1 And Enhances Abt-737 Mediated Cell Death In Malignant Human Glioma Cell Lines
  440. Dinaciclib, A Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation Of Mcl-1 And Enhances Abt-737–Mediated Cell Death In Malignant Human …
  441. Diphenhydramine Induces Melanoma Cell Apoptosis By Suppressing Stat3/Mcl-1 Survival Signaling And Retards B16-F10 Melanoma Growth In Vivo
  442. Direct Regulation Of Mitochondrial Fatty Acid Oxidation By Anti-Apoptotic Mcl-1
  443. Direct Repression Of The Mcl-1 Promoter By E2F1
  444. ‐Directed Binding For The Discovery Of Modulators Of Α‐Helix‐Mediated Protein–Protein Interactions: Proof‐Of‐Concept Studies With The Apoptosis Regulator Mcl‐1
  445. Discovery And Characterization Of 2, 5-Substituted Benzoic Acid Dual Inhibitors Of The Anti-Apoptotic Mcl-1 And Bfl-1 Proteins
  446. Discovery And Characterization Of New Small-Molecule Inhibitors Of Mcl-1 By High-Throughput Screening
  447. Discovery And Development Of 1, 2, 3, 4-Tetrahydroisoquinoline-3-Carboxylic Acid Derivatives As Bcl-2/Mcl-1 Inhibitors
  448. Discovery And Development Of Substituted Tyrosine Derivatives As Bcl-2/Mcl-1 Inhibitors
  449. Discovery And In Vivo Evaluation Of Macrocyclic Mcl-1 Inhibitors Featuring An Α-Hydroxy Phenylacetic Acid Pharmacophore Or Bioisostere
  450. Discovery And Structure-Activity Relationship Studies Of N-Substituted Indole Derivatives As Novel Mcl-1 Inhibitors
  451. Discovery Of 2-Indole-Acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods
  452. Discovery Of A Potent Inhibitor Of Melk That Inhibits Expression Of The Anti-Apoptotic Protein Mcl-1 And Tnbc Cell Growth
  453. Discovery Of Mcl-1 Inhibitors Based On A Thiazolidine-2, 4-Dione Scaffold
  454. Discovery Of Mcl-1 Inhibitors From Integrated High Throughput And Virtual Screening
  455. Discovery Of Mcl-1-Specific Inhibitor Azd5991 And Preclinical Activity In Multiple Myeloma And Acute Myeloid Leukemia
  456. Discovery Of Novel Biaryl Sulfonamide Based Mcl-1 Inhibitors
  457. Discovery Of Novel Small Molecule Inhibitors Of The Antiapoptotic Protein Mcl-1 Through High-Throughput Screening Approach
  458. Discovery Of Orally Bioavailable Novel Mcl-1 Inhibitors That Exhibit Selective Anti-Proliferative Activity In Mcl-1 Sensitive Cancer Cell Lines
  459. Discovery Of Potent 2-Indole-Acylsulfonamide Mcl-1 Inhibitors Using Structure Guided Fragment-Based Methods
  460. Discovery Of Potent And Selective Mcl-1 Inhibitors Using Fragment-Based Methods And Structure-Based Design.
  461. Discovery Of Potent Mcl-1/Bcl-Xl Dual Inhibitors By Using A Hybridization Strategy Based On Structural Analysis Of Target Proteins
  462. Discovery Of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods And Structure-Based Design
  463. Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate In Vivo Activity In Mouse Xenograft Models Of Human Cancer
  464. Discovery Of Selective Mcl-1 Inhibitors Via Structure-Based Design And Structure-Activity Relationship Analysis
  465. Discovery Of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods And Structure-Based Design
  466. Discovery Of Β-Carboline Copper (Ii) Complexes As Mcl-1 Inhibitor And In Vitro And In Vivo Activity In Cancer Models
  467. Disruption Of Mcl-1· Bim Complex In Granzyme B-Mediated Mitochondrial Apoptosis
  468. Distinct Roles For Extracellular-Signal-Regulated Protein Kinase (Erk) Mitogen-Activated Protein Kinases And Phosphatidylinositol 3-Kinase In The Regulation Of Mcl-1 …
  469. Distribution Of Bim Determines Mcl-1 Dependence Or Co-Dependence On Bcl-Xl/Bcl-2 In Multiple Myeloma
  470. Distribution Of Bim Determines Mcl-1 Dependence Or Codependence With Bcl-Xl/Bcl-2 In Mcl-1–Expressing Myeloma Cells
  471. Divaricoside Exerts Antitumor Effects, In Part, By Modulating Mcl-1 In Human Oral Squamous Cell Carcinoma Cells
  472. Dna Damage Response And Mcl-1 Destruction Initiate Apoptosis In Adenovirus-Infected Cells
  473. Dna Damaging Agent-Induced Apoptosis Is Controled By Mcl-1 Phosphorylation And Degradation Mediated By The Noxa/Mcl-1/Cdk2 Complex
  474. Dna Damaging Agent-Induced Apoptosis Is Regulated By Mcl-1 Phosphorylation And Degradation Mediated By The Noxa/Mcl-1/Cdk2 Complex
  475. Does N-Terminal Processing Of Mcl-1 Occur At Mitochondrial Outer Membrane Or Matrix?
  476. Downregulation Of Bcl-X L And Mcl-1 Is Sufficient To Induce Cell Death In Mesothelioma Cells Highly Refractory To Conventional Chemotherapy
  477. Down-Regulation Of C-Flip, Xiap And Mcl-1 Protein As Well As Depletion Of Reduced Glutathione Contribute To The Apoptosis Induction Of Glycyrrhenitic Acid Derivatives In …
  478. Downregulation Of Mcl-1 And Upregulation Of Puma Using Mtor Inhibitors Enhance Antitumor Efficacy Of Bh3 Mimetics In Triple-Negative Breast Cancer
  479. Downregulation Of Mcl-1 By Daunorubicin Pretreatment Reverses Resistance Of Breast Cancer Cells To Tnf-Related Apoptosis-Inducing Ligand
  480. Downregulation Of Mcl-1 By Diallyl Disulfide Induces G2/M Arrest In Human Leukemia K562 Cells And Its Mechanism
  481. Down-Regulation Of Mcl-1 By Inhibition Of The Pi3-K/Akt Pathway Is Required For Cell Shrinkage-Dependent Cell Death
  482. Down-Regulation Of Mcl-1 By Small Interfering Rna Sensitizes Resistant Melanoma Cells To Fas-Mediated Apoptosis
  483. Downregulation Of Mcl-1 Has Anti-Inflammatory Pro-Resolution Effects And Enhances Bacterial Clearance From The Lung
  484. Downregulation Of Mcl-1 Potentiates Hdaci-Mediated Apoptosis In Leukemic Cells
  485. Downregulation Of Mcl-1 Synergizes The Apoptotic Response To Combined Treatment With Cisplatin And A Novel Fiber Chimeric Oncolytic Adenovirus
  486. Downregulation Of Mcl-1 Through Gsk-3Β Activation Contributes To Arsenic Trioxide-Induced Apoptosis In Acute Myeloid Leukemia Cells
  487. Downregulation Of Mcl-1 Through Inhibition Of Translation Contributes To Benzyl Isothiocyanate-Induced Cell Cycle Arrest And Apoptosis In Human Leukemia Cells
  488. Down-Regulation Of Mcl-1 With Antisense Technology Alters The Effect Of Various Cytotoxic Agents Used In Treatment Of Squamous Cell Carcinoma Of The Head And Neck
  489. Downregulation Of Mir‐20B‐5P Facilitates Mycobacterium Tuberculosis Survival In Raw 264.7 Macrophages Via Attenuating The Cell Apoptosis By Mcl‐1 Upregulation
  490. Down-Regulation Of Mir-320 Associated With Cancer Progression And Cell Apoptosis Via Targeting Mcl-1 In Cervical Cancer
  491. Downregulation Of Mir-363 Increases Drug Resistance In Cisplatin-Treated Hepg2 By Dysregulating Mcl-1
  492. Downregulation Of The Antiapoptotic Mcl‐1 Protein And Apoptosis In Ma‐11 Breast Cancer Cells Induced By An Anti‐Epidermal Growth Factor Receptor–Pseudomonas …
  493. Drug Combinations Co-Targeting Myeloid Cell Leukemia-1 (Mcl-1) Protein Can Overcome Microenvironmentally-Induced Multi-Drug Tolerance In Non-Hodgkin …
  494. Dual Inhibition Of Bcl-Xl And Mcl-1 Is Required To Induce Tumour Regression In Lung Squamous Cell Carcinomas Sensitive To Fgfr Inhibition
  495. Dual Inhibition Of Mcl-1 By The Combination Of Carfilzomib And Tg02 In Multiple Myeloma
  496. Dual Inhibitors Of The Pro-Survival Proteins Bcl-2 And Mcl-1 Derived From Natural Compound Meiogynin A
  497. Dual Modulation Of Mcl-1 And Mtor Determines The Response To Sunitinib
  498. Dual Targeting Of Noxa/Mcl-1 Synergistically Induces Cell Death In Mantle Cell Lymphoma (Mcl) Cells
  499. Dynamic Changes In Mcl-1 Expression Regulate Macrophage Viability Or Commitment To Apoptosis During Bacterial Clearance
  500. Dynamic Changes In Mcl-1 Expression Regulate Macrophage Viability Or Commitment To Apoptosis During Bacterial Clearance.
  501. Dynamic Regulation Of Long-Chain Fatty Acid Oxidation By A Noncanonical Interaction Between The Mcl-1 Bh3 Helix And Vlcad
  502. Dynein Light Chain 1 Induces Assembly Of Large Bim Complexes On Mitochondria That Stabilize Mcl-1 And Regulate Apoptosis
  503. E.; Thorne, Rick F.; Allen, John; Hersey, Peter; Zhang, Xu Dong.“Up-Regulation Of Mcl-1 Is Critical For Survival Of Human Melanoma Cells Upon Endoplasmic …
  504. E3 Ligase Fbw7 Participates In Oxidative Stress‑Induced Myocardial Cell Injury Via Interacting With Mcl‑1
  505. Early Downregulation Of Mcl-1 Regulates Apoptosis Triggered By Cardiac Glycoside Unbs1450
  506. Eat/Mcl-1 Expression In The Human Embryonal Carcinoma Cells Undergoing Differentiation Or Apoptosis
  507. Eat/Mcl‐1, A Member Of The Bcl‐2 Related Genes, Confers Resistance To Apoptosis Induced By Cis‐Diammine Dichloroplatinum (Ii) Via A P53‐Independent Pathway
  508. Ectopic Overexpression Of Laptm5 Results In Lysosomal Targeting And Induces Mcl-1 Down-Regulation, Bak Activation, And Mitochondria-Dependent Apoptosis …
  509. Effect Of (-)-Gossypol (At-101) On Transcriptional Regulation Of Noxa And Puma And On Mcl-1-Mediated Cancer Cell Resistance To Apoptosis
  510. Effect Of Acquired Resistance To Lapatinib In Her2-Positive Breast Cancer Cells On The Bcl-2 Family Members Mcl-1 And Bax.
  511. Effect Of Antisense Oligodeoxynucleotide Targeting Mcl-1 On Proliferation And Apoptosis Of Hepatocarcinoma Cells [J]
  512. Effect Of Arsenic Trioxide On Apoptosis In Lymphoblastoid Raji Cell Line With Relation To Expression Of Mcl-1 Gene
  513. Effect Of Curcumin On Apoptosis And Expression Of Apoptosis Regulating Proteins Mcl-1, Bax, Bak In Primary Acute Myeloid Leukemic Cells
  514. Effect Of Mcl-1 Antisense Oligonucleotide On Hela Cell Biology And Sensitivity Of Chemotherapy
  515. Effect Of Mir-29B On The Proliferation And Apoptosis Of Pulmonary Artery Smooth Muscle Cells By Targeting Mcl-1 And Ccnd2
  516. Effect Of Mir-363 On The Proliferation, Invasion And Apoptosis Of Laryngeal Cancer By Targeting Mcl-1
  517. Effect Of Vascular Endothelial Growth Factor On Apoptosis And Expression Of Bcl-2 And Mcl-1 In Acute Leukemia Cells
  518. Effective Caspase Inhibition Blocks Neutrophil Apoptosis And Reveals Mcl-1 As Both A Regulator And A Target Of Neutrophil Caspase Activation
  519. Effectiveness Of Small Interfering Rna (Sirna) Against The Mcl-1 Gene In A Canine Mammary Gland Tumor Cell Line
  520. Effects Of Casticin On Apoptosis And Expression Of Mcl-1 Protein In Ovarian Cancer Coc1 Cells [J]
  521. Effects Of Natural Products On Mcl-1 Expression And Function
  522. Effects Of Overexpressed Mcl-1 In Apoptosis Induced By The Er Stress Inducers Of Gastric Adenocarcinoma Cells [J]
  523. Effects Of The Mcl-1/Bcl-2 Inhibitor Gx015-070 (Obatoclax®) On Growth And Viability Of Canine And Human Neoplastic Mast Cells
  524. Efficacy Of Hcc Treatment With Proteasome Inhibitor Bortezomib Is Increased By Oncolytic Virotherapy Mediated Downregulation Of Mcl-1 And Bip
  525. Efficiently Kills Imatinib-Resistant Chronic Eosinophilic Leukemia Cells Harboring Gatekeeper Mutant T674I Fip1L1-Pdgfrα: Roles Of Mcl-1 And Β-Catenin
  526. Egf-Mediated Induction Of Mcl-1 At The Switch To Lactation Is Essential For Alveolar Cell Survival
  527. Egfr Mutations And Akt Phosphorylation Are Markers For Sensitivity To Combined Mcl-1 And Bcl-2/Xl Inhibition In Non-Small Cell Lung Cancer
  528. Egfr Regulates Mcl-1 Dependence In Chemoresistant And Acquired Abt-737-Resistant High-Risk Neuroblastoma (Hr Nb).
  529. Egfr Signaling Defines Mcl-1 Survival Dependency In Neuroblastoma
  530. Elevated Expression Of Mcl-1 Inhibits Apoptosis And Predicts Poor Prognosis In Patients With Surgically Resected Non-Small Cell Lung Cancer
  531. Elevated Expression Of The Apoptotic Regulator Mcl-1 At The Time Of Leukemic Relapse
  532. Elevated Mcl-1 Inhibits Thymocyte Apoptosis And Alters Thymic Selection
  533. Elevated Mcl-1 Perturbs Lymphopoiesis, Promotes Transformation Of Hematopoietic Stem/Progenitor Cells, And Enhances Drug Resistance
  534. Elimination Of Mcl-1 Is Required For The Initiation Of Apoptosis Following Ultraviolet Irradiation
  535. Elk4 Neutralization Sensitizes Glioblastoma To Apoptosis Through Downregulation Of The Anti-Apoptotic Protein Mcl-1
  536. Emerging Role Of Mcl-1 In Actively Counteracting Bh3-Only Proteins In Apoptosis
  537. Endiandric Acid Analogues From Beilschmiedia Ferruginea As Dual Inhibitors Of Bcl-Xl/Bak And Mcl-1/Bid Interactions
  538. Endogenous Association Of Bim Bh3‐Only Protein With Mcl‐1, Bcl‐Xl And Bcl‐2 On Mitochondria In Human B Cells
  539. Endogenous Bak Inhibitors Mcl-1 And Bcl-Xl: Differential Impact On Trail Resistance In Bax-Deficient Carcinoma
  540. Enhanced Apoptotic Effects By Downregulating Mcl-1: Evidence For The Improvement Of Photodynamic Therapy With Celecoxib
  541. Enhanced Apoptotic Effects By The Combination Of Curcumin And Methylseleninic Acid: Potential Role Of Mcl‐1 And Fak
  542. Enhanced Killing Of Melanoma Cells By Simultaneously Targeting Mcl-1 And Noxa
  543. Enhanced Production Of Anti-Pd1 Antibody In Cho Cells Through Transient Co-Transfection With Anti-Apoptotic Genes Bcl-Xl And Mcl-1
  544. Enhancement Of Cell Survival By Stromal Cell-Derived Factor-1/Cxcl12 Involves Activation Of Creb And Induction Of Mcl-1 And C-Fos In Factor-Dependent Human Cell …
  545. Enhancement Of Chemosensitivity By Simultaneously Silencing Of Mcl-1 And Survivin Genes Using Small Interfering Rna In Human Myelomonocytic Leukaemia
  546. Ephrina1 Induces Microrna-302B Expression In Malignant Mesothelioma Cells And Suppresses Tumor Growth Via Repression Of Mcl-1 Gene
  547. Epidermal Growth Factor (Egf) Suppresses Staurosporine-Induced Apoptosis By Inducing Mcl-1 Via The Mitogen-Activated Protein Kinase Pathway
  548. Epidermal Growth Factor Regulates Mcl-1 Expression Through The Mapk-Elk-1 Signalling Pathway Contributing To Cell Survival In Breast Cancer
  549. Epox Inhibits Angiogenesis By Degradation Of Mcl-1 Through Erk Inactivation
  550. Er Stress Sensitizes Cells To Trail Through Down-Regulation Of Flip And Mcl-1 And Perk-Dependent Up-Regulation Of Trail-R2
  551. Eradication Of Acute Myeloid Leukemia Is Enhanced By Combined Bcl-2 And Mcl-1 Targeting
  552. Erk Signaling Induces Apoptosis Of Acute Myelogenous Leukemia Cells Via Inhibition Of Eukaryotic Initiation Factor 4E-Binding Protein 1 And Down-Regulation Of Mcl-1
  553. Erk1/2 And The Bcl-2 Family Proteins Mcl-1, Tbid, And Bim Are Involved In Inhibition Of Apoptosis During Persistent Chlamydia Psittaci Infection
  554. Erk1/2‐Dependent Phosphorylation Of Bimel Promotes Its Rapid Dissociation From Mcl‐1 And Bcl‐Xl
  555. Erratum: Antigen-Affinity Controls Pre-Germinal Center B Cell Selection By Promoting Mcl-1 Induction Through Baff Receptor Signaling
  556. Erratum: The Ratio Of Mcl-1 And Noxa Determines Abt737 Resistance In Squamous Cell Carcinoma Of The Skin
  557. Establishing Drug Discovery And Identification Of Hit Series For The Anti-Apoptotic Proteins, Bcl-2 And Mcl-1
  558. Estrogen Regulation Of Anti-Apoptotic Bcl-2 Family Member Mcl-1 Expression In Breast Cancer Cells
  559. Ethacrynic Acid Oxadiazole Analogs Induce Apoptosis In Malignant Hematologic Cells Through Downregulation Of Mcl-1 And C-Flip, Which Was Attenuated By Gstp1-1
  560. Ets-1 Mediates Upregulation Of Mcl-1 Downstream Of Xbp-1 In Human Melanoma Cells Upon Er Stress
  561. Eupafolin Enhances Trail-Mediated Apoptosis Through Cathepsin S-Induced Down-Regulation Of Mcl-1 Expression And Ampk-Mediated Bim Up-Regulation In …
  562. Evaluating The Role Of Mcl-1 And Its Interacting Partners In Radioresistance Of Oral Cancer Cells
  563. Evaluation And Critical Assessment Of Putative Mcl-1 Inhibitors
  564. Evaluation Of Mcl-1 Inhibitors In Preclinical Models Of Multiple Myeloma
  565. Evaluation Of Pten And Mcl-1 Expressions In Nsclc Expressing Wild-Type Or Mutated Egfr
  566. Evidence For A Protective Role Of Mcl-1 In Proteasome Inhibitor-Induced Apoptosis
  567. Evodiamine Induces Apoptosis And Enhances Apoptotic Effects Of Erlotinib In Wild-Type Egfr Nsclc Cells Via S6K1-Mediated Mcl-1 Inhibition
  568. Evodiamine Induces Apoptosis And Enhances Trail-Induced Apoptosis In Human Bladder Cancer Cells Through Mtor/S6K1-Mediated Downregulation Of Mcl-1
  569. Exon Skipping In Mcl-1 Results In A Bcl-2 Homology Domain 3 Only Gene Product That Promotes Cell Death
  570. Exposure To The Viral By-Product Dsrna Or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis Via A Bim/Mcl-1 Imbalance
  571. Expression And Clinical Significance Of Mcl-1 In B Cell Non-Hodgkin’S Lymphoma
  572. Expression And Clinical Significance Of Mcl-1 In T-Cell Non-Hodgkin’S Lymphoma
  573. Expression And Prognostic Relevance Of Mcl-1 In Breast Cancer
  574. Expression And Regulation Of The Anti-Apoptotic Mcl-1 Protein In Human B-Cell Lymphoma.
  575. Expression And Significance Of Mir-125A And Mcl-1 In Intestinal Tissue After Massive Small Bowel Resection In Rat
  576. Expression And Significance Of Mrna And Protein Of Eif4E, P-Eif4E And Mcl-1 In Pathological Scar
  577. Expression Levels Of P18Ink4C Modify The Cellular Efficacy Of Cyclin-Dependent Kinase Inhibitors Via Regulation Of Mcl-1 Expression In Tumor Cell Lines
  578. Expression Of Bcl-2, Bcl-X, Mcl-1, Bax And Bak In Human Uterine Leiomyomas And Myometrium During The Menstrual Cycle And After Menopause
  579. Expression Of Bcl-Xl And Mcl-1 In The Nonmelanoma Skin Cancers Of Renal Transplant Recipients
  580. Expression Of Mcl-1 And Bak Proteins In Nutritional Anemia And Its Clinical Significance
  581. Expression Of Mcl-1 And Bcl-2 Oncoproteins In Reactive And Neoplastic Lymphoid Tissues
  582. Expression Of Mcl-1 And Ki-67 In Papillary Thyroid Carcinomas
  583. Expression Of Mcl-1 And Microrna-29A In Extranodal Nk/T-Cell Lymphoma Tissue
  584. Expression Of Mcl-1 And P53 Proteins Predicts The Survival Of Patients With T3 Gastric Carcinoma
  585. Expression Of Mcl-1 In Cerebellar Granule Neurons Is Regulated By Igf-I In A Developmentally Specific Fashion
  586. Expression Of Mcl‐1 In Mantle Cell Lymphoma Is Associated With High‐Grade Morphology, A High Proliferative State, And P53 Overexpression
  587. Expression Of Mcl-1 In Primary Acute Myeloid Leukemia Cells And Its Clinical Significance
  588. Expression Of Mcl-1 Protein In Human Cervical Lesions And Its Significance [J]
  589. Expression Of Mcl-1 Splicing Variants In Clear-Cell Renal Cancer And Their Correlation With Histopathological Parameters And Prognosis
  590. Expression Of The Bcl-2 Homologue Mcl-1 Correlates With Survival Of Peripheral Blood B Lymphocytes
  591. Expression Of The Epstein Barr Virus Transforming Protein Lmp1 Causes A Rapid And Transient Stimulation Of The Bcl-2 Homologue Mcl-1 Levels In B-Cell Lines
  592. Expression Of Vegf-A/C, Vegf-R2, Pdgf-Α/Β, C-Kit, Egfr, Her-2/Neu, Mcl-1 And Bmi-1 In Merkel Cell Carcinoma
  593. Expression Pattern And Biologic Relevance Of Bcl-2 And Mcl-1 In Pulmonary Neuroendocrine Tumors.
  594. Expression Profile Of Bcl-2, Bcl-Xl, And Mcl-1 Predicts Pharmacological Response To The Bcl-2 Selective Antagonist Venetoclax In Multiple Myeloma Models
  595. Exth-55. Concomitant Inhibition Of Rac1 And Bcl-2/Bcl-Xl Interferes With The Mcl-1/Usp9X Axis And Yields Synergistic Anti-Glioma Activity
  596. Farnesyltransferase Inhibitor Bms-214662 Induces Apoptosis In Myeloma Cells Through Puma Up-Regulation, Bax And Bak Activation, And Mcl-1 Elimination
  597. Fas-Mediated Neutrophil Apoptosis Is Accelerated By Bid, Bak, And Bax And Inhibited By Bcl-2 And Mcl-1
  598. Fbw7 Mutations Mediate Resistance Of Colorectal Cancer To Targeted Therapies By Blocking Mcl-1 Degradation
  599. Fbw7-Dependent Mcl-1 Degradation Mediates The Anticancer Effect Of Hsp90 Inhibitors
  600. Fbxo4 Inhibits Lung Cancer Cell Survival By Targeting Mcl-1 For Degradation
  601. Fbxw 7 Modulates Malignant Potential And Cisplatin‐Induced Apoptosis In Cholangiocarcinoma Through Notch 1 And Mcl 1
  602. Fenretinide Inactivation Of Mcl-1 Enhanced Activity Of The Bcl-2 Family Inhibitor Abt-737 In Acute Lymphoblastic Leukemia Cell Lines
  603. First Evidence That Oligopyridines, Α-Helix Foldamers, Inhibit Mcl-1 And Sensitize Ovarian Carcinoma Cells To Bcl-Xl-Targeting Strategies
  604. First Mcl-1-Selective Bh3 Mimetics As Potential Therapeutics For Targeted Treatment Of Cancer
  605. First-In-Class Cell-Penetrating Proteins Targeting Mcl-1 Induce Tumor Cell Apoptosis And Inhibition Of Tumor Growth In Vivo
  606. Five-Co-Ordinate Cobalt (Ii) And Nickel (Ii) Complexes Of 1, 4, 8, 11-Tetrakis (Diphenylphosphinomethyl)-1, 4, 8, 11-Tetraazacyclotetradecane (Tpta),[Mcl (Tpta)] X [X= Clo4 …
  607. Fl118, A Survivin/Mcl-1/Xiap/Ciap2-Selective Inhibitor, Effectively Inhibits Human Mesothelioma Xenograft Growth In Animal Models.
  608. Flash Knockdown Sensitizes Cells To Fas-Mediated Apoptosis Via Down-Regulation Of The Anti-Apoptotic Proteins, Mcl-1 And Cflip Short
  609. Flavones Induce Neutrophil Apoptosis By Down-Regulation Of Mcl-1 Via A Proteasomal-Dependent Pathway
  610. Flavonoid Morin Inhibits Proliferation And Induces Apoptosis Of Melanoma Cells By Regulating Reactive Oxygen Species, Sp1 And Mcl-1
  611. Flavopiridol Decreases Mcl-1 And Initiates Early Mitochondrial Damage In Chronic Lymphocytic Leukemia (Cll) Cells.
  612. Flavopiridol Decreases Mcl-1 And Xiap In Acute Myeloid Leukemia Cell Resulting In Augmentation Of Sorafenib-Induced Apoptosis
  613. Flexibility And Specificity Of The Interaction Of Mcl-1 With Bim Bh3
  614. Flexibility Enables To Discriminate Between Ligands: Lessons From Structural Ensembles Of Bcl-Xl And Mcl-1
  615. Flt3 Inhibitor Fi-700 Neutralizes Mcl-1 And Enhances P53-Mediated Apoptosis In Acute Myeloid Leukemia (Aml) Cells With Activating Mutations Of Flt3 Via Mcl-1 …
  616. Flt3 Kinases In Flt3-Itd Acute Myeloid Leukemia Post-Translationally Downregulates The Anti-Apoptotic Protein Mcl-1 Through Downregulation Of The Mcl-1 …
  617. Flt3-Itd Confers Resistance To The Pi3K/Akt Pathway Inhibitors By Protecting The Mtor/4Ebp1/Mcl-1 Pathway Through Stat5 Activation In Acute Myeloid …
  618. Flt3-Itd Up-Regulates Mcl-1 To Promote Survival Of Stem Cells In Acute Myeloid Leukemia Via Flt3-Itd–Specific Stat5 Activation
  619. Fludarabine Induces Apoptosis In Chronic Lymphocytic Leukemia-The Role Of P53, Bcl-2, Bax, Mcl-1, And Bag-1 Proteins
  620. Fluorouracil-Induced Death Of Jurkat T-Cells–A Role For Caspases And Mcl-1
  621. Foam Cell Formation And Atherosclerotic Plaque Apoptosis And Markedly Decreased Neutrophil Recruitment In Ldlr-/-Mice Lacking Macrophage Mcl-1
  622. Forodesine Induces P53-Independent Apoptosis In Chronic Lymphocytic Leukemia Through Caspase-8 Activation, Mcl-1 Downregulation, Conformational Changes Of Bax …
  623. Fragment‐Based Design, Synthesis, And Biological Evaluation Of 1‐Substituted‐Indole‐2‐Carboxylic Acids As Selective Mcl‐1 Inhibitors
  624. Fragment-Based Design, Synthesis, And Biological Evaluation Of N-Substituted-5-(4-Isopropylthiophenol)-2-Hydroxynicotinamide Derivatives As Novel Mcl-1 Inhibitors
  625. Fragment-Based Discovery Of Potent Inhibitors Of The Anti-Apoptotic Mcl-1 Protein
  626. Free Ligand 1D Nmr Conformational Signatures To Enhance Structure Based Drug Design Of A Mcl-1 Inhibitor (Azd5991) And Other Synthetic Macrocycles
  627. Frequent Stat3 Activation Is Associated With Mcl‐1 Expression In Nasal Nk‐Cell Lymphoma
  628. From Meiogynin A To The Synthesis Of Dual Inhibitors Of Bcl-Xl And Mcl-1 Anti-Apoptotic Proteins
  629. Fty720 Enhances Trail-Mediated Apoptosis By Up-Regulating Dr5 And Down-Regulating Mcl-1 In Cancer Cells
  630. Fty720 Induces Autophagy-Associated Apoptosis In Human Oral Squamous Carcinoma Cells, In Part, Through A Reactive Oxygen Species/Mcl-1-Dependent …
  631. Functional Analysis Of The Human Mcl-1 Gene
  632. Functional Capacity Of Mcl-1-Specific Cytotoxic T-Cells
  633. Furowanin A-Induced Autophagy Alleviates Apoptosis And Promotes Cell Cycle Arrest Via Inactivation Stat3/Mcl-1 Axis In Colorectal Cancer
  634. Galectin 3 Protein Network Analysis By Reverse Protein Arrays Demonstrates Regulation Of Mcl-1, Pkc Delta And Cd74 Associated With Poor Survival In Patients …
  635. Gamma Irradiation Of Human Leukaemic Cells Hl-60 And Molt-4 Induces Decrease In Mcl-1 And Bid, Release Of Cytochrome C, And Activation Of Caspase-8 And …
  636. Gamma-Secretase Inhibition Attenuates Oxaliplatin-Induced Apoptosis Through Increased Mcl-1 And/Or Bcl-Xl In Human Colon Cancer Cells
  637. Gastrin Increases Mcl-1 Expression In Type I Gastric Carcinoid Tumors And A Gastric Epithelial Cell Line That Expresses The Cck-2 Receptor
  638. Gcs-100, A Novel Galectin-3 Antagonist, Modulates Mcl-1, Noxa, And Cell Cycle To Induce Myeloma Cell Death
  639. Gdc-0941 Sensitizes Breast Cancer To Abt-737 In Vitro And In Vivo Through Promoting The Degradation Of Mcl-1
  640. Genetic Biomarkers Predict Response To Dual Bcl-2 And Mcl-1 Targeting In Acute Myeloid Leukaemia Cells
  641. Genipin Induces Mitochondrial Dysfunction And Apoptosis Via Downregulation Of Stat3/Mcl-1 Pathway In Gastric Cancer
  642. Geraniin Suppresses Ovarian Cancer Growth Through Inhibition Of Nf‐Κb Activation And Downregulation Of Mcl‐1 Expression
  643. Gfi-1 Inhibits Proliferation And Colony Formation Of P210Bcr/Abl-Expressing Cells Via Transcriptional Repression Of Stat 5 And Mcl-1
  644. Glucocorticoid-Induced Leucine Zipper Is Expressed In Human Neutrophils And Promotes Apoptosis Through Mcl-1 Down-Regulation
  645. Glutamine Catabolism Maintains Mcl-1 Expression In Glucose-Deprived Multiple Myeloma
  646. Glutathione And Bcl-2 Targeting Facilitates Elimination By Chemoradiotherapy Of Human A375 Melanoma Xenografts Overexpressing Bcl-Xl, Bcl-2, And Mcl-1
  647. Glycogen Synthase Kinase 3Α And 3Β Mediate A Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1
  648. Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization And Apoptosis By Destabilization Of Mcl-1
  649. Glycolysis Inhibition Sensitizes Tumor Cells To Death Receptors-Induced Apoptosis By Amp Kinase Activation Leading To Mcl-1 Block In Translation
  650. Glycolysis Inhibition Targets Mcl-1 To Restore Sensitivity Of Lymphoma Cells To Abt-737-Induced Apoptosis
  651. Gm-Csf Rescues Tf-1 Cells From Growth Factor Withdrawal-Induced, But Not Differentiation-Induced Apoptosis: The Role Of Bcl-2 And Mcl-1
  652. Gö6976, A Flt3 Kinase Inhibitor, Exerts Potent Cytotoxic Activity Against Acute Leukemia Via Inhibition Of Survivin And Mcl-1
  653. Go6976, A Potent Flt3 Kinase Inhibitor, Exerts Antiproliferative Activity Against Acute Myeloid Leukemia Via Inhibition Of Survivin And Mcl-1 In The Presence Of …
  654. Gossypol Induces Apoptosis In Multiple Myeloma Cells By Inhibition Of Interleukin-6 Signaling And Bcl-2/Mcl-1 Pathway
  655. Granulocyte Macrophage Colony-Stimulating Factor Signaling And Proteasome Inhibition Delay Neutrophil Apoptosis By Increasing The Stability Of Mcl-1
  656. Gsk3Β And Mcl-1 Mediate Cardiomyocyte Apoptosis In Response To High Glucose
  657. Guarding Effector T-Cell Survival: All For One, Mcl-1 For All?
  658. H1, A Derivative Of Tetrandrine, Enhances The Efficacy Of 5-Fu In Bel7402/5-Fu Cells Via Suppressing Stat3/Mcl-1 And Inducing Puma
  659. Harringtonine Induces Apoptosis In Nb4 Cells Through Down-Regulation Of Mcl-1
  660. Hb-Egf Is Associated With Dna Damage And Mcl-1 Turnover In Human Glioma Cell Lines Treated By Temozolomide
  661. Hbx Sensitizes Cells To Oxidative Stress-Induced Apoptosis By Accelerating The Loss Of Mcl-1 Protein Via Caspase-3 Cascade
  662. Hepatitis B Virus X Protein Enhances Cisplatin-Induced Hepatotoxicity Via A Mechanism Involving Degradation Of Mcl-1
  663. Hepatocyte Growth Factor Induces Mcl‐1 In Primary Human Hepatocytes And Inhibits Cd95‐Mediated Apoptosis Via Akt
  664. Herceptin Sensitizes Erbb2 (Her2/Neu) Over Expressing Cells To Apoptosis By Reducing Anti-Apoptotic Mcl-1 Expression
  665. Herceptin Sensitizes Erbb2–Overexpressing Cells To Apoptosis By Reducing Antiapoptotic Mcl-1 Expression
  666. Heterodimerization Of Bak And Mcl-1 Activated By Detergent Micelles
  667. Hif‐1Α Has An Anti‐Apoptotic Effect In Human Airway Epithelium That Is Mediated Via Mcl‐1 Gene Expression
  668. High Bcl-2/Mcl-1 Gene Expression Ratio Identifies Molecular Sub-Groups Of Multiple Myeloma Patients Extremely Sensitive To Abt-737
  669. High Expression Of Mcl-1 In Alk Positive And Negative Anaplastic Large Cell Lymphoma
  670. High-Grade Malignant Non-Hodgkin’S Lymphomas Differ From Low-Grade Lymphomasin The Extent Of Apoptosis Andtheir Expression Of Bcl-2, Mcl-1, Bax And P53
  671. High-Quality Nmr Structure Of Human Anti-Apoptotic Protein Domain Mcl-1 (171-327) For Cancer Drug Design
  672. Hispidulin Sensitizes Human Ovarian Cancer Cells To Trail-Induced Apoptosis By Ampk Activation Leading To Mcl-1 Block In Translation
  673. Homoharringtonine Interacts Synergistically With Bortezomib In Nhl Cells Through Mcl-1 And Noxa-Dependent Mechanisms
  674. Homoharringtonine Reduced Mcl-1 Expression And Induced Apoptosis In Chronic Lymphocytic Leukemia
  675. Hot-Spots Of Mcl-1 Protein.
  676. Hot-Spots Of Mcl-1 Protein: Miniperspective
  677. Hsp90 Inhibitor 17-Aag Sensitizes Bcl-2 Inhibitor (-)-Gossypol By Suppressing Erk-Mediated Protective Autophagy And Mcl-1 Accumulation In Hepatocellular …
  678. Hsp90 Inhibitor Nvp-Auy922 Enhances Trail-Induced Apoptosis By Suppressing The Jak2-Stat3-Mcl-1 Signal Transduction Pathway In Colorectal Cancer Cells
  679. Htlv-1 Tax Stabilizes Mcl-1 Via Traf6-Dependent K63-Linked Polyubiquitination To Promote Cell Survival And Transformation
  680. Hu J, Dang N, Menu E, Et Al. Activation Of Atf4 Mediates Unwanted Mcl-1 Accumulation By Proteasome Inhibition. Blood. 2012; 119 (3): 826-837.
  681. Human Chronic Leukemic Cells By Abnobaviscum® Flaxini, Mistletoe Extracts From Ash Tree: Involvement Of Activation Of Caspases, Mcl-1 Down-Regulation, And …
  682. Human Eosinophils Express Bcl-2 Family Proteins: Modulation Of Mcl-1 Expression By Ifn-Γ
  683. Human Glioma Cells To Histone Deacetylase Inhibitors Depends On Reactive Oxygen Species Production, Mitochondrial Dysfunction, Noxa Upregulation And Mcl-1 …
  684. Human Oral Cancers Have Altered Expression Of Bcl‐2 Family Members And Increased Expression Of The Anti‐Apoptotic Splice Variant Of Mcl‐1
  685. Human Papillomavirus Type 16/18 Up-Regulates The Expression Of Interleukin-6 And Antiapoptotic Mcl-1 In Non–Small Cell Lung Cancer
  686. Humanized Mcl-1 Mice Enable Accurate Preclinical Evaluation Of Mcl-1 Inhibitors Destined For Clinical Use
  687. Hydroxyquinoline-Derived Compounds And Analoguing Of Selective Mcl-1 Inhibitors Using A Functional Biomarker
  688. Hyperactive Ptpn11 Mutations Alters Leukemic Stem Cell Frequency Through Mcl-1 Overexpression
  689. Hypoxia Selects For High-Metastatic Lewis Lung Carcinoma Cells Overexpressing Mcl-1 And Exhibiting Reduced Apoptotic Potential In Solid Tumors
  690. Hypoxia-Induced P38 Mapk Activation Reduces Mcl-1 Expression And Facilitates Sensitivity Towards Bh3 Mimetics In Chronic Lymphocytic Leukemia
  691. Hypoxic Human Cancer Cells Are Sensitized To Bh-3 Mimetic–Induced Apoptosis Via Downregulation Of The Bcl-2 Protein Mcl-1
  692. Identification Of A Non-Canonical Bh3 Peptide That Binds The Bh3 Pocket Of Mcl-1
  693. Identification Of A Novel Mcl-1 Protein Binding Motif
  694. Identification Of An Hla-A1 Restricted Ctl Epitope From Mcl-1
  695. Identification Of Mcl-1 As A Bcr/Abl-Dependent Target In Chronic Myeloid Leukemia (Cml): Evidence For Cooperative Antileukemic Effects Of Imatinib And Mcl-1 …
  696. Identification Of Novel Mcl-1 Inhibitors Using Integrated Screening Approach: Combining High Throughput And Virtual Screening.
  697. Identification Of Small‐Molecule Inhibitors Of The Antiapoptotic Protein Myeloid Cell Leukaemia‐1 (Mcl‐1)
  698. Identifying Mcl-1 Protein Dependencies Using Dimerization-Specific Antibody Biomarker For Predicting Response To Targeted Apoptosis Inducing Therapies.
  699. Identifying The Druggable Interactome Of Ews-Fli1 Reveals Mcl-1 Dependent Differential Sensitivities Of Ewing Sarcoma Cells To Apoptosis Inducers
  700. Iex-1-Induced Cell Death Requires Bim And Is Modulated By Mcl-1
  701. Ifn-Α And Bortezomib Overcome Bcl-2 And Mcl-1 Overexpression In Melanoma Cells By Stimulating The Extrinsic Pathway Of Apoptosis
  702. Ige-Dependent Activation Of Human Mast Cells Up-Regulates Flip And Mcl-1 Anti-Apoptotic Proteins
  703. Il‐15 Regulates Bcl‐2 Family Members Bim And Mcl‐1 Through Jak/Stat And Pi3K/Akt Pathways In T Cells
  704. Il-22 Accelerates Thymus Regeneration Via Stat3/Mcl-1 And Decreases Chronic Graft-Versus-Host Disease In Mice After Allotransplants
  705. Il-27 Inhibits Ifn-Γ Induced Autophagy By Concomitant Induction Of Jak/Pi3 K/Akt/Mtor Cascade And Up-Regulation Of Mcl-1 In Mycobacterium Tuberculosis H37Rv …
  706. Il-32Γ Delays Spontaneous Apoptosis Of Human Neutrophils Through Mcl-1, Regulated Primarily By The P38 Mapk Pathway
  707. Il-6 Inhibits Apoptosis And Retains Oxidative Dna Lesions In Human Gastric Cancer Ags Cells Through Up-Regulation Of Anti-Apoptotic Gene Mcl-1
  708. Il-6 Inhibits Apoptosis Of Human Myeloma Cell Line Xg-7 Through Activation Of Jak/Stat Pathway And Up-Regulation Of Mcl-1.
  709. Il-6 Rescues The Hyporesponsiveness Of C-Rel Deficient B Cells Independent Of Bcl-Xl, Mcl-1, And Bcl-2
  710. Il‐6 Up‐Regulates Mcl‐1 In Human Myeloma Cells Through Jak/Stat Rather Than Ras/Map Kinase Pathway
  711. Il-6-Independent Expression Of Mcl-1 In Human Multiple Myeloma
  712. Imbalance In Alternative Splicing Of Mcl-1 Inhibits Apoptosis In Diffuse Large B-Cell Lymphoma
  713. Immunoblot Analysis Of Cellular Expression Of Bcl-2 Family Proteins, Bcl-2, Bax, Bcl-X And Mcl-1, In Human Peripheral Blood And Lymphoid Tissues
  714. Immunoexpressions Of P21, Rb, Mcl-1 And Bad Gene Products In Normal, Hyperplastic And Carcinomatous Human Prostates
  715. Immunohistochemical Analysis Of Bcl-2, Bax, Bcl-X, And Mcl-1 Expression In Pancreatic Cancers
  716. Immunohistochemical Analysis Of Bcl-2, Bax, Bcl-X, And Mcl-1 Expression In Prostate Cancers.
  717. Immunohistochemical Analysis Of Bcl-2, Bax, Mcl-1, And Bcl-X Expression In Ovarian Surface Epithelial Tumors.
  718. Immunohistochemical Analysis Of Bcl-2, Bcl-X, Mcl-1, And Bax In Tumors Of Central And Peripheral Nervous System Origin.
  719. Immunohistochemical Analysis Of Mcl-1 And Bcl-2 Proteins In Normal And Neoplastic Lymph Nodes.
  720. Immunohistochemical Analysis Of Mcl-1 Protein In Human Tissues. Differential Regulation Of Mcl-1 And Bcl-2 Protein Production Suggests A Unique Role For Mcl-1 In …
  721. Immunohistochemical Analysis Of The Antiapoptotic Mcl‐1 And Bcl‐2 Proteins In Follicular Lymphoma
  722. Immunohistochemical Localization Of Mcl‐1 And Bcl‐2 Proteins In Thymic Epithelial Tumours
  723. Immunohistochemical Measurement And Expression Of Mcl-1 In Infertile Testes
  724. Immunohistochemical Staining For Bcl-2 And Mcl-1 In Intrathyroidal Epithelial Thymoma (Itet)/Carcinoma Showing Thymus-Like Differentiation (Castle) And Cervical …
  725. Impact Of Elevated Anti-Apoptotic Mcl-1 And Bcl-2 On The Development And Treatment Of Mll-Af9 Aml In Mice
  726. Imperatorin Acts As A Cisplatin Sensitizer Via Downregulating Mcl-1 Expression In Hcc Chemotherapy
  727. Imperatorin Induces Mcl-1 Degradation To Cooperatively Trigger Bax Translocation And Bak Activation To Suppress Drug-Resistant Human Hepatoma
  728. Imperatorin Targets Mcl-1 To Sensitize Cd133+ Lung Cancer Cells To Γδ-T Cell-Mediated Cytotoxicity
  729. Importance Of Mcl-1 For Alveolar Macrophage Apoptosis–Associated Bacterial Killing
  730. Improved Binding Affinities Of Pyrrolidine Derivatives As Mcl-1 Inhibitors By Modifying Amino Acid Side Chains
  731. In B-Cells Isolated From Chronic Lymphocytic Leukemia Patients And Leukemia Cell Lines Is Overcome By The Pleiotropic Kinase Inhibitor Quercetin Through Mcl-1 Down …
  732. In Human Multiple Myeloma Cells Promotes Myeloma Cell Growth And Survival In The Bone Marrow Microenvironment Via Upregulated Mcl-1 And Nfκb Signaling
  733. In Non-Transformed Cells Bak Activates Upon Loss Of Anti-Apoptotic Bcl-X L And Mcl-1 But In The Absence Of Active Bh3-Only Proteins
  734. In Silico Approaches To Identify Novel Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors For Treatment Of Cancer
  735. In Vitro Thymidine Kinase/Ganciclovir-Based Suicide Gene Therapy Using Replication Defective Herpes Simplex Virus-1 Against Leukemic B-Cell Malignancies (Mcl, Hcl …
  736. In Vivo Localisation And Stability Of Human Mcl‐1 Using Green Fluorescent Protein (Gfp) Fusion Proteins
  737. In Vivo Rna Silencing Ofthe Mcl-1 Gene Confers Increased Susceptibility Of Melanoma Cells To Apoptosis
  738. In Whole Blood: Involvement Of The Phosphoinositide 3-Kinase/Akt And Nf-Κb Signaling Pathways, Leading To Increased Levels Of Mcl-1, A1, And Phosphorylated Bad
  739. Increased Expression Of Mcl-1 And Bcl-Xl And Decreased Expression Of Bcl-2 Associated With Melanoma Progression And Transcription Factors
  740. Increased Expression Of Mcl-1 Is Required For Protection Against Serum Starvation In Phosphatase And Tensin Homologue On Chromosome 10 Null Mouse Embryonic …
  741. Increased Expression Of Mcl‐1 Is Responsible For The Blockage Of Trail‐Induced Apoptosis Mediated By Egf/Erbb1 Signaling Pathway
  742. Increased Foam Cell Formation And Atherosclerotic Plaque Apoptosis In Ldlr−/− Mice Lacking Macrophage Mcl-1
  743. Increased Leukocyte Survival And Accelerated Onset Of Lymphoma In The Absence Of Mcl-1 S159-Phosphorylation
  744. Increased Mcl–1 Expression Is Associated With Poor Prognosis In Ovarian Carcinomas
  745. Increased Mcl-1 Expression Predicts Poor Prognosis And Disease Recurrence In Acute Myeloid Leukemia
  746. Increased Synthesis Of Mcl-1 Protein Underlies Initial Survival Of Egfr-Mutant Lung Cancer To Egfr Inhibitors And Provides A Novel Drug Target
  747. Individualized Mitochondrial Functional Approach To Combination Of Bcl-2 And Mcl-1 Antagonism In Acute Myeloid Leukemia
  748. Indomethacin Causes Renal Epithelial Cell Injury Involving Mcl-1 Down-Regulation
  749. Induces Anti-Proliferative And Apoptotic Activities In Human Hormone-Refractory Prostate Cancer Through Histamine Receptor-Independent Mcl-1 Cleavage And Bak Up …
  750. Induces Apoptosis In A Subset Of Cancer Cells (Lung Cancer, Colon Cancer And Mesothelioma) By Disrupting Bcl-Xl And Mcl-1 Protein–Protein Interactions …
  751. Induces Apoptosis Of Aml Blasts And Their Terminal Differentiation By Blocking Akt/Erk Survival Signals And Downregulating Bcl-2, Mcl-1 And Cyclin-D1 …
  752. Induces Cell Death In Multiple Myeloma Cells By Inhibition Of Rna Polymerase Ii–Dependent Transcription And Down-Regulation Of Mcl-1
  753. Induces Expression Of Pim Kinases Through Stat5 To Confer Resistance To The Pi3K/Akt Pathway Inhibitors On Leukemic Cells By Enhancing The Mtorc1/Mcl-1 …
  754. Inducing Apoptosis And Enhancing Chemosensitivity To Gemcitabine Via Rna Interference Targeting Mcl-1 Gene In Pancreatic Carcinoma Cell
  755. Induction By Clinically Active Flt3 Inhibitors In Flt3-Itd Acute Myeloid Leukemia Cells In Vitro And In Vivo Through Synergistic Downregulation Of Mcl-1 And Of Bcl …
  756. Induction Of Apoptosis And Anti-Tumor Effects Of A Novel Pan Inhibitor Of Bcl-2 And Mcl-1 Apogossypolone (Apog2) In Multiple Myeloma Cells.
  757. Induction Of Apoptosis By Mcl-1 Inhibitors In Chronic Lymphocytic Leukemia Cells
  758. Induction Of Apoptosis In Large Granular Lymphocyte (Lgl) Leukemia By Jak Tyrosine Kinase Inhibitor Ag-490: Role Of Stat3-Regulated Mcl-1
  759. Induction Of Noxa Sensitizes Human Colorectal Cancer Cells Expressing Mcl-1 To The Small-Molecule Bcl-2/Bcl-Xl Inhibitor, Abt-737
  760. Infectious Pancreatic Necrosis Virus Induces Apoptosis Due To Down-Regulation Of Survival Factor Mcl-1 Protein Expression In A Fish Cell Line
  761. Inhibiting Mcl-1 With An Antisense Oligonucleotide Induces Cell Death In Acute Myeloid Leukemia Cells
  762. Inhibiting Mitochondrial-Dependent Proteolysis Of Mcl-1 Promotes Resistance To Dna Damage
  763. Inhibition Delays Neutrophil Apoptosis Via Cyclic Amp-Independent Activation Of Protein Kinase A And Protein Kinase A-Mediated Stabilization Of Mcl-1 And X-Linked …
  764. Inhibition Of Antiapoptotic Bcl-Xl, Bcl-2, And Mcl-1 Proteins By Small Molecule Mimetics
  765. Inhibition Of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity Through Modulation Of Leukemia-Stromal Interactions And Metabolic Functions In Aml
  766. Inhibition Of Anti-Apoptotic Protein Mcl-1 And Epigenetic Reader Brd4 With Small Molecule Inhibitors: Structure-Based Drug Design And Polypharmacology
  767. Inhibition Of Constitutive And Bcr-Induced Syk Activation Downregulates Mcl-1 And Induces Apoptosis In Chronic Lymphocytic Leukemia B Cells
  768. Inhibition Of Cyclin E1 Overcomes Temozolomide Resistance In Glioblastoma By Mcl‐1 Degradation
  769. Inhibition Of Cyclin E1 Sensitizes Hepatocellular Carcinoma Cells To Regorafenib By Mcl-1 Suppression
  770. Inhibition Of Mcl-1 Blocks The Development Of Kras-Driven Adenocarcinoma Of The Lung
  771. Inhibition Of Mcl‐1 By Obatoclax Sensitizes Sp2/0‐Ag14 Hybridoma Cells To Glutamine Deprivation‐Induced Apoptosis
  772. Inhibition Of Mcl-1 Enhances Cell Death Induced By The Bcl-2-Selective Inhibitor Abt-199 In Acute Myeloid Leukemia Cells
  773. Inhibition Of Mcl-1 Enhances Lapatinib Toxicity And Overcomes Lapatinib Resistance Via Bak-Dependent Autophagy
  774. Inhibition Of Mcl-1 Enhances Pevonedistat-Triggered Apoptosis In Osteosarcoma Cells
  775. Inhibition Of Mcl-1 Enhances The Efficacy Of Tyrosine Kinase Inhibition In Flt3 Mutated Aml And Synergizes With Venetoclax Targeting Aml Stem Cells
  776. Inhibition Of Mcl-1 Expression By Citrate Enhances The Effect Of Bcl-Xl Inhibitors On Human Ovarian Carcinoma Cells
  777. Inhibition Of Mcl-1 In Breast Cancer Cells Promotes Cell Death In Vitro And In Vivo
  778. Inhibition Of Mcl-1 In Mammary And Cns Tumor Cells Promotes Cell Death In Vitro And In Vivo
  779. Inhibition Of Mcl-1 Promotes Senescence In Cancer Cells: Implications For Preventing Tumor Growth And Chemotherapy Resistance
  780. Inhibition Of Mcl-1 Through Covalent Modification Of A Noncatalytic Lysine Side Chain
  781. Inhibition Of Mcl-1 With The Pan–Bcl-2 Family Inhibitor (–) Bi97D6 Overcomes Abt-737 Resistance In Acute Myeloid Leukemia
  782. Inhibition Of Mir-302 Suppresses Hypoxia-Reoxygenation-Induced H9C2 Cardiomyocyte Death By Regulating Mcl-1 Expression
  783. Inhibition Of Nanog/Nanogp8 Downregulates Mcl-1 In Colorectal Cancer (Crc) Cells, Enhances The Efficacy Of Bh3 Mimetics And Inhibits Clonogenicity
  784. Inhibition Of Nanog/Nanogp8 Downregulates Mcl-1 In Colorectal Cancer Cells And Enhances The Therapeutic Efficacy Of Bh3 Mimetics
  785. Inhibition Of P38 Α Mapk Enhances Proteasome Inhibitor-Induced Apoptosis Of Myeloma Cells By Modulating Hsp27, Bcl-X L, Mcl-1 And P53 Levels In Vitro And …
  786. Inhibition Of Polo Like Kinase 1 In Sarcomas Induces Apoptosis That Is Dependent On Mcl-1 Suppression
  787. Inhibition Of Pp2A Prevents Mcl-1 Dephosphorylation At The Thr-163/Ser-159 Phosphodegron, Dramatically Reducing Expression In Mcl-1-Amplified Lymphoma Cells
  788. Inhibition Of Proteasomal Degradation Of Mcl-1 By Cobalt Chloride Suppresses Cobalt Chloride-Induced Apoptosis In Hct116 Colorectal Cancer Cells
  789. Inhibition Of Protein Geranylgeranylation Induces Apoptosis In Myeloma Plasma Cells By Reducing Mcl-1 Protein Levels
  790. Inhibition Of Sphingosine Kinase 2 Downregulates The Expression Of C-Myc And Mcl-1 And Induces Apoptosis In Multiple Myeloma
  791. Inhibition Of Stat3 Signaling Leads To Apoptosis Of Leukemic Large Granular Lymphocytes And Decreased Mcl-1 Expression
  792. Inhibition Of Store-Operated Channels By Carboxyamidotriazole Sensitizes Ovarian Carcinoma Cells To Anti-Bclxl Strategies Through Mcl-1 Down-Regulation
  793. Inhibition Of Syk More Effectively Overcomes Mcl-1 Mediated Abt-199 Resistance Of Bcr-Stimulated Cll Cells Than Inhibition Of Btk Or Pi3Kdelta
  794. Inhibition Of The Jak-Stat3-Mcl-1 Axis By Combining Ruxolitinib With S63845 Completely Prevents Plasmacytoma Growth In The Gp130-Regulated Ina-6 Xenograft …
  795. Inhibition Of The Mek1/2/Erk1/2 Pathway Sensitizes Human Leukemia Cells To Perifosine-Mediated Lethality Through A Jnk-, Akt-, And Mcl-1-Dependent Process
  796. Inhibition Of Two Gastric Cancer Cell Lines Induced By Fucoxanthin Involves Downregulation Of Mcl-1 And Stat3
  797. Inhibition Of Usp9X Deubiquitinase Activity By Wp1130 Reduces Mcl-1 Levels And Induces Apoptosis In Cells From Patients With Plasma Cell Dyscrasia And Drug-Refractory …
  798. Inhibition Of Xpo 1 Enhances Cell Death Induced By Abt‐199 In Acute Myeloid Leukaemia Via Mcl‐1
  799. Inhibition Sensitizes Non–Small Cell Lung Cancer With T790M Mutation To Irreversible Egfr Inhibitors Via Translational Suppression Of Mcl-1 By Ampk Activation
  800. Inhibitor Celecoxib Can Suppress The Proliferation Of Flt3-Itd Positive Acute Myeloid Leukemia Cells With Prominent Down Regulation Of Mek/Mcl-1 Expression In Vitro
  801. Inhibitor Nvp-Bez235-Induced Apoptosis In Human Renal Carcinoma Caki Cells Through Down-Regulation Of P53-Dependent Bcl-2 Expression And Inhibition Of Mcl-1 …
  802. Inhibitor Ym-155 Sensitizes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand-Resistant Glioma Cells To Apoptosis Through Mcl-1 Downregulation And By …
  803. Inhibitors Of The Antiapoptotic Myeloid Cell Leukemia-1 (Mcl-1) May Provide Effective Treatment For Cancer
  804. Inhibits Jak2 Transcription And Induces Apoptosis In Human Myeloproliferative Disorder Cells Bearing Jak2V617F Through Caspase-3-Mediated Cleavage Of Mcl-1
  805. Integrated Genomics Identifies Mir-32/Mcl-1 Pathway As A Critical Driver Of Melanomagenesis: Implications For Mir-Replacement And Combination Therapy
  806. Interactions Between Cancer-Associated Fibroblasts And Tumor Cells Promote Mcl-1 Dependency In Estrogen Receptor-Positive Breast Cancers
  807. Interferon Α Extends The Survival Of Human Myeloma Cells Through An Upregulation Of The Mcl‐1 Anti‐Apoptotic Molecule
  808. Interleukin (Il)-7 Promotes T-Cell Survival By Stabilization Of Mcl-1
  809. Interleukin 15–Mediated Survival Of Natural Killer Cells Is Determined By Interactions Among Bim, Noxa And Mcl-1
  810. Interleukin-13 In Combination With Cd40 Ligand Potently Inhibits Apoptosis In Human B Lymphocytes: Upregulation Of Bcl-Xl And Mcl-1
  811. Interleukin‐15 Delays Human Neutrophil Apoptosis By Intracellular Events And Not Via Extracellular Factors: Role Of Mcl‐1 And Decreased Activity Of Caspase‐3 And …
  812. Interleukin-3 Stimulation Of Mcl-1 Gene Transcription Involves Activation Of The Pu. 1 Transcription Factor Through A P38 Mitogen-Activated Protein Kinase-Dependent …
  813. Interleukin-6 Contributes To Mcl-1 Up-Regulation And Trail Resistance Via An Akt-Signaling Pathway In Cholangiocarcinoma Cells
  814. Interleukin-6 Expression Through Mapk/P38/Nf-Κb Signaling Pathway And The Resultant Antiapoptotic Effect On Endothelial Cells Through Mcl-1 Expression With Sil6-Rα
  815. Interrelated Roles For Mcl-1 And Bim In Regulation Of Trail-Mediated Mitochondrial Apoptosis
  816. Intersection Of Mitochondrial Fission And Fusion Machinery With Apoptotic Pathways: Role Of Mcl‐1
  817. Intracellular Targeting Of The Oncogenic Muc1-C Protein With A Go-203 Nanoparticle Formulation Overcomes Mcl-1-And Bfl-1-Mediated Resistance In Human …
  818. Intracellular Zinc Release-Activated Erk-Dependent Gsk-3 Β–P53 And Noxa–Mcl-1 Signaling Are Both Involved In Cardiac Ischemic-Reperfusion Injury
  819. Intrinsic Resistance Of Prostate Cancer To The Bh3 Mimetic Abt-737 Is Related To Expression Of The Anti-Apoptotic Mcl-1 And Additional Survival And Apoptosis Regulating …
  820. Introduction Of Constitutivelly Active Akt In Primary Cll B-Cells Results In Upregulation Of Mcl-1, Bcl-Xl And Cyclin D3 And Promotes Leukemic Cell Survival.
  821. Investigating The Functional Roles Of Mcl-1 In Apoptosis In Mammalian Cells
  822. Investigation Of The Role Of Mcl-1 And Mer In The Regulation Of Eosinophil Apoptosis And Efferocytosis
  823. In-Vitro Treatment Of Lymphoma Cell Lines With Bay 43-9006 (Sorafenib) Is Followed By Typical Features Of Apoptosis And Down-Regulation Of Mcl-1 Pointing To An …
  824. Involvement Of Eat/Mcl-1, An Anti-Apoptotic Bcl-2-Related Gene, In Murine Embryogenesis And Human Development
  825. Ionizing Radiation Sensitizes Breast Cancer Cells To Bcl-2 Inhibitor, Abt-737, Through Regulating Mcl-1
  826. Ionizing Radiation-Inducible Microrna Mir-193A-3P Induces Apoptosis By Directly Targeting Mcl-1
  827. Ipnv Vp5, A Novel Anti-Apoptosis Gene Of The Bcl-2 Family, Regulates Mcl-1 And Viral Protein Expression
  828. Irinotecan Treatment And Senescence Failure Promote The Emergence Of More Transformed And Invasive Cells That Depend On Anti-Apoptotic Mcl-1
  829. Islet Cell Hyperplasia In Transgenic Mice Overexpressing Eat/Mcl-1, A Bcl-2 Related Gene
  830. Isolation And Identification Of Cyclic Polyketides From Endiandra Kingiana Gamble (Lauraceae), As Bcl-Xl/Bak And Mcl-1/Bid Dual Inhibitors, And Approaches Toward The …
  831. Iterative Optimization Yields Mcl-1–Targeting Stapled Peptides With Selective Cytotoxicity To Mcl-1–Dependent Cancer Cells
  832. Itraq-Based Quantitative Proteomic Analysis Of The Anti-Apoptotic Effect Of Hyperin, Which Is Mediated By Mcl-1 And Bid, In H2O2-Injured Ea. Hy926 Cells
  833. Jaceosidin Induces Apoptosis Through Bax Activation And Down-Regulation Of Mcl-1 And C-Flip Expression In Human Renal Carcinoma Caki Cells
  834. Jak2V617F Drives Mcl-1 Expression And Sensitizes Acute Myeloid Leukemia Cells To Dual Inhibition Of Jak2 And Bcl-Xl
  835. Jak2V617F Drives Mcl-1 Expression And Sensitizes Hematologic Cell Lines To Dual Inhibition Of Jak2 And Bcl-Xl
  836. Junduqing Extractive Promotes The Apoptosis Of Nasopharyngeal Carcinoma Cells Through Down-Regulating Mcl-1 And Bcl-Xl And Up-Regulating Caspase-3, Caspase-8 …
  837. Juvenile Doxorubicin Treatment Impairs Recovery And Promotes Apoptosis In Adult Hearts Via Failure Of Up-Regulation Of Mcl-1 After Myocardial Infarction
  838. Key Survival Factor, Mcl-1, Correlates With Sensitivity To Combined Bcl-2/Bcl-Xl Blockade
  839. Kills Human Leukemia Cells Via Down-Regulation Of Mcl-1 Through A Transcriptional …
  840. Kinase Axis Enhances Cytotoxic Effects Of Proteasome Inhibitors On Flt3-Itd–Positive Aml Cells By Cooperatively Inhibiting The Mtorc1/4Ebp1/S6K/Mcl-1 …
  841. -Kinase Inhibtor Sorafenib Interacts Synergistically With The Hdac Inhibitor Vorinostat To Induce Apoptosis In Cml Cells In Association With Downregulation Of Mcl-1 …
  842. Kingianins O–Q: Pentacyclic Polyketides From Endiandra Kingiana As Inhibitor Of Mcl-1/Bid Interaction
  843. Klf4 And Yy1 Are Resistant Factors In Nhl And Potential Therapeutic Targets: The New Resistant Nf-Κb/Yy1/Klf4/Bclxl/Mcl-1 Axis
  844. Knee Joint Immobility Induces Mcl-1 Gene Expression In Articular Chondrocytes
  845. Knockdown Of Microrna-203 Alleviates Lps-Induced Injury By Targeting Mcl-1 In C28/I2 Chondrocytes
  846. Knockdown Of P53 Levels In Human Keratinocytes Accelerates Mcl-1 And Bcl-X L Reduction Thereby Enhancing Uv-Light Induced Apoptosis
  847. Knockdown Of The Foxm1 Enhances The Sensitivity Of Gastric Cancer Cells To Cisplatin By Targeting Mcl-1
  848. Kribb11 Accelerates Mcl-1 Degradation Through An Hsf1-Independent, Mule-Dependent Pathway In A549 Non-Small Cell Lung Cancer Cells
  849. Kröhnke Pyridines: Rapid And Facile Access To Mcl-1 Inhibitors
  850. Lack Of Mcl-1 Confers Resistance To Bortezomid In Multiple Myeloma.
  851. Lactate Dehydrogenase 5 Expression In Melanoma Increases With Disease Progression And Is Associated With Expression Of Bcl-Xl And Mcl-1, But Not Bcl-2 …
  852. Lana-1, Bcl-2, Mcl-1 And Hif-1Α Protein Expression In Hiv-Associated Kaposi Sarcoma
  853. Lapatinib And Obatoclax Kill Cns Tumor Cells Through Blockade Of Erbb1/3/4 And Through Inhibition Of Bcl-Xl And Mcl-1
  854. Lapatinib And Obatoclax Kill Tumor Cells Through Blockade Of Erbb1/3/4 And Through Inhibition Of Bcl-Xl And Mcl-1
  855. Lapatinib Resistance In Hct116 Cells Is Mediated By Elevated Mcl-1 Expression And Decreased Bak Activation And Not By Erbb Receptor Kinase Mutation
  856. Leishmania Donovani Exploits Myeloid Cell Leukemia 1 (Mcl-1) Protein To Prevent Mitochondria-Dependent Host Cell Apoptosis
  857. Leptin Stimulates Ovarian Cancer Cell Growth And Inhibits Apoptosis By Increasing Cyclin D1 And Mcl-1 Expression Via The Activation Of The Mek/Erk1/2 And Pi3K/Akt …
  858. Leptin Stimulates Ovarian Cancer Cell Growth And Inhibits Apoptosis By Increasing Cyclin D1 And Mcl-1 Expression Via The Activation Of The Mek/Erk1/2 And …
  859. Leptin Stimulates Ovarian Cancer Cell Growth And Inhibits Apoptosis By Increasing Cyclin D1 And Mcl-1 Expression Via The Activation Of The Mek/Erk1/2 …
  860. Leptomycin B-Induced Apoptosis Is Mediated Through Caspase Activation And Down-Regulation Of Mcl-1 And Xiap Expression, But Not Through The Generation Of Ros In …
  861. Leukaemia Inhibitory Factor Protects Cholangiocarcinoma Cells From Cytotoxicity Via A Stat-3-Independent, Mcl-1 Activation
  862. Leukemia Inhibitory Factor Protects Cholangiocarcinoma Cells From Drug-Induced Apoptosis Via A Pi3K/Akt-Dependent Mcl-1 Activation
  863. L-Gossypol Inhibits Nf-Κb, Down Regulates Mcl-1 And Induces Apoptosis Of Primary Acute Myeloid Leukaemia Cells.
  864. Light Induced Apoptosis Is Accelerated In Transgenic Retina Overexpressing Human Eat/Mcl-1, An Anti-Apoptotic Bcl-2 Related Gene
  865. Lipidoid Nanoparticle Mediated Silencing Of Mcl-1 Induces Apoptosis In Mantle Cell Lymphoma
  866. Lipoic Acid Decreases Mcl-1, Bcl-X L And Up Regulates Bim On Ovarian Carcinoma Cells Leading To Cell Death
  867. Lncrna H19 Overexpression Induces Bortezomib Resistance In Multiple Myeloma By Targeting Mcl-1 Via Mir-29B-3P
  868. Lncrna Tug1 Contributes To Escc Progression Via Regulating Mir‐148A‐3P/Mcl‐1/Wnt/Β‐Catenin Axis In Vitro
  869. Long Noncoding Rna Itgb1 Promotes Migration And Invasion Of Clear Cell Renal Cell Carcinoma By Downregulating Mcl-1
  870. Long Noncoding Rna Linc00152 Promotes Cell Proliferation Through Competitively Binding Endogenous Mir‐125B With Mcl‐1 By Regulating Mitochondrial Apoptosis …
  871. Long Non‐Coding Rna Myoslid Functions As A Competing Endogenous Rna To Regulate Mcl‐1 Expression By Sponging Mir‐29C‐3P In Gastric Cancer
  872. Long Noncoding Rna Pvt1 Inhibits Renal Cancer Cell Apoptosis By Up-Regulating Mcl-1
  873. Loss In Mcl-1 Function Sensitizes Non-Hodgkin’S Lymphoma Cell Lines To The Bcl-2-Selective Inhibitor Venetoclax (Abt-199)
  874. Loss Of A Single Mcl-1 Allele Inhibits Myc-Driven Lymphomagenesis By Sensitizing Pro-B Cells To Apoptosis
  875. Loss Of Mcl-1 Leads To Impaired Autophagy And Rapid Development Of Heart Failure
  876. Loss Of Mcl-1 Protein And Inhibition Of
  877. Loss Of Mcl-1 Protein And Inhibition Of Electron Transport Chain Together Induce Anoxic Cell Death
  878. Loss Of P53 And Altered Mir15-A/16-1Mcl-1 Pathway In Cll: Insights From Tcl1-Tg:P53−/− Mouse Model And Primary Human Leukemia Cells
  879. Loss Of Pkcδ Induces Prostate Cancer Resistance To Paclitaxel Through Activation Of Wnt/Β-Catenin Pathway And Mcl-1 Accumulation
  880. Low Affinity Interaction With Cll B-Cell Receptors Induces Apoptosis By Down-Regulating Mcl-1 And Up-Regulating Bimel.
  881. Low Carbohydrate Diet Prevents Mcl-1-Mediated Resistance To Bh3-Mimetics
  882. Low Human And Murine Mcl-1 Expression Leads To A Pro-Apoptotic Plaque Phenotype Enriched In Giant-Cells
  883. Low Mcl-1 Mrna Expression Correlates With Prolonged Survival In B-Cell Chronic Lymphocytic Leukemia
  884. Low-Dose Actinomycin D Decreases Mcl-1 Expression And Acts Synergistically With Abt-737 To Induce Apoptosis Of Sclc Cell Lines
  885. Low‐Molecular‐Mass Hyaluronan Induces Pulmonary Inflammation By Up‐Regulation Of Mcl‐1 To Inhibit Neutrophil Apoptosis Via Pi 3K/Akt1 Pathway
  886. Lycorine Induces Apoptosis And Down-Regulation Of Mcl-1 In Human Leukemia Cells
  887. Lysophosphatidic Acid Induces Upregulation Of Mcl-1 And Protects Apoptosis In A Ptx-Dependent Manner In H19-7 Cells
  888. M. Leprae Inhibits Apoptosis In Thp-1 Cells By Downregulation Of Bad And Bak And Upregulation Of Mcl-1 Gene Expression
  889. M2I-1 Disrupts The In Vivo Interaction Between Cdc20 And Mad2 And Increases The Sensitivities Of Cancer Cell Lines To Anti-Mitotic Drugs Via Mcl-1S
  890. Ma27. 09 Dual Inhibition Of Bcl-Xl And Mcl-1 Is Required To Induce Tumour Regression In Lung Squamous Cell Carcinomas Sensitive To Fgfr Inhibition
  891. Macc1 Regulates Death Receptor Mediated Apoptosis In Solid Cancers Through Stat1/3–Mcl-1 Signaling
  892. Macc1 Regulates Fas Mediated Apoptosis Through Stat1/3–Mcl-1 Signaling In Solid Cancers
  893. Macrophages Confer Survival Signals Via Ccr1-Dependent Translational Mcl-1 Induction In Chronic Lymphocytic Leukemia
  894. Magnolin Promotes Autophagy And Cell Cycle Arrest Via Blocking Lif/Stat3/Mcl-1 Axis In Human Colorectal Cancers
  895. Male Sterility In Mcl-1-Flox Mice Is Not Due To Enhanced Mcl1 Protein Stability
  896. Mapk P38 And Jnk Have Opposing Activities On Trail-Induced Apoptosis Activation In Nsclc H460 Cells That Involves Rip1 And Caspase-8 And Is Mediated By Mcl-1
  897. Mapk/P38/Nf-Kb Signaling Pathway For Radiation Increased Il-6 Expression Of Endothelial Cells With Anti-Apoptosis Effect Through Mcl-1
  898. Mapping The Bh3 Binding Interface Of Bcl-Xl, Bcl-2, And Mcl-1 Using Split-Luciferase Reassembly
  899. Marinopyrrole Derivatives With Sulfide Spacers As Selective Disruptors Of Mcl-1 Binding To Pro-Apoptotic Protein Bim
  900. Maritoclax And Dinaciclib Inhibit Mcl-1 Activity And Induce Apoptosis In Both A Mcl-1-Dependent And-Independent Manner
  901. Maritoclax Induces Apoptosis In Acute Myeloid Leukemia Cells With Elevated Mcl-1 Expression
  902. Maritoclax, A Selective Mcl-1 Inhibitor, Sensitizes Melanoma Cells To The Bad Bh3-Mimetic Abt-737.
  903. Mbp-1 Upregulates Mir-29B, Which Represses Mcl-1, Collagens, And Matrix Metalloproteinase-2 In Prostate Cancer Cells
  904. Mcl-1
  905. Mcl-1 And Bax In The Fetal Ovary: Studies Of The Undernourished Pregnant Ewe
  906. Mcl-1 And Bcl-2 Expression In Neuroendocrine Carcinoma (Nec) And Potential For New Therapeutic Target.
  907. Mcl‐1 And Bcl‐2/Bax Ratio Are Associated With Treatment Response But Not With Rai Stage In B‐Cell Chronic Lymphocytic Leukemia
  908. Mcl-1 And Bcl-X L Sequestration Of Bak Confers Differential Resistance To Bh3-Only Proteins
  909. Mcl‐1 And Bcl‐Xl Are Co‐Regulated By Il‐6 In Human Myeloma Cells
  910. Mcl-1 And Bcl-Xl Are Essential For Survival Of The Developing Nervous System
  911. Mcl‐1 And Bcl‐Xl Cooperatively Maintain Integrity Of Hepatocytes In Developing And Adult Murine Liver
  912. Mcl-1 And Bcl-Xl Coordinately Regulate Megakaryocyte Survival
  913. Mcl-1 And Bcl-Xl Regulate Bak/Bax-Dependent Apoptosis Of The Megakaryocytic Lineage At Multistages
  914. Mcl-1 And Bcl-Xl-Dependent Resistance To The Bcl-2 Inhibitor Abt-199 Can Be Overcome By Preventing Pi3K/Akt/Mtor Activation In Lymphoid …
  915. Mcl-1 And Fbw7 Control A Dominant Survival Pathway Underlying Hdac And Bcl-2 Inhibitor Synergy In Squamous Cell Carcinoma
  916. Mcl-1 And Its Role In Cancer Research
  917. Mcl-1 And Mir-181C In Gata2 Mutation Associated Monomac And Familial Myelodysplastic Syndrome
  918. Mcl-1 And Pka/Ampk Axis Fuel Venetoclax Resistance In Lymphoid Cancers
  919. Mcl-1 And Tumor Cell Persistence
  920. Mcl-1 And Vdac Interaction Promotes Mitochondrial Ca2+ Uptake And Ros Production (1159.12)
  921. Mcl-1 And Yy1 Inhibition And Induction Of Dr5 By The Bh3-Mimetic Obatoclax (Gx15-070) Contribute In The Sensitization Of B-Nhl Cells To Trail Apoptosis
  922. Mcl-1 Antagonism Enhances The Anti-Invasive Effects Of Dasatinib In Pancreatic Adenocarcinoma
  923. Mcl-1 Antagonism Is A Potential Therapeutic Strategy In A Subset Of Solid Cancers
  924. Mcl-1 Antagonizes Bax/Bak To Promote Effector Cd4+ And Cd8+ T-Cell Responses
  925. Mcl-1 Antisense Therapy Chemosensitizes Human Melanoma In A Scid Mouse Xenotransplantation Model
  926. Mcl-1 As A Buffer For Proapoptotic Bcl-2 Family Members During Trail-Induced Apoptosis A Mechanistic Basis For Sorafenib (Bay 43-9006)-Induced …
  927. Mcl-1 As A Possible Predictor Of Progression-Free Survival In Previously Untreated Chronic Lymphocytic Leukemia Patients Treated With Pentostatin …
  928. Mcl-1 As A Potential Therapeutic Target For Human Hepatocelluar Carcinoma
  929. Mcl-1 As A Therapeutic Target In Acute Myelogenous Leukemia (Aml)
  930. Mcl-1 Attenuates Vinblastine-Induced Apoptosis In Ml-1 Leukemia Cells
  931. Mcl-1 Blocks Radiation-Induced Apoptosis And Inhibits Clonogenic Cell Death
  932. Mcl-1 But Not Bcl-Xl Is Critical For The Development And Sustained Expansion Of Thymic Lymphoma In P53-Deficient Mice
  933. Mcl-1 Cleavage And Sustained Phosphorylation Of C-Jun-N-Terminal Kinase Mediate Melanoma Apoptosis Induced By 2-Acetyl Furanonaphthoquinone: Roles Of Bcl-2 …
  934. Mcl-1 Confers Protection Of Her2-Positive Breast Cancer Cells To Hypoxia: Therapeutic Implications
  935. Mcl-1 Correlates With Reduced Apoptosis In Neutrophils From Patients With Sepsis
  936. Mcl-1 Couples Mitochondrial Dynamic Machinery To Mitochondrial Quality Control In Response To Stress
  937. Mcl-1 Critically Regulates Survival Of T-Lymphocyte Non-Hodgkin Lymphoma
  938. Mcl-1 Deficiency Results In Peri-Implantation Embryonic Lethality
  939. Mcl-1 Degradation During Hepatocyte Lipoapoptosis
  940. Mcl-1 Degradation Is Required For Targeted Therapeutics To Eradicate Colon Cancer Cells
  941. Mcl-1 Degradation Mediated By Jnk Activation Via Mekk1/Tak1-Mkk4
  942. Mcl-1 Degradation Mediated By Jnk Activation Via Mekk1/Tak1-Mkk4 Contributes To Anticancer Activity Of New Tubulin Inhibitor Mt189
  943. Mcl-1 Dependence Predicts Response To Vorinostat And Gemtuzumab Ozogamicin In Acute Myeloid Leukemia
  944. Mcl-1 Dependency Is A Predictive Biomarker For Apoptotic Induction By Short-Term Dinaciclib (Sch 727965) Treatment
  945. Mcl-1 Dependency Of Cisplatin-Resistant Cancer Cells
  946. Mcl-1 Depletion Impairs Dna Double-Strand Break Repair And Reinitiation Of Stalled Dna Replication Forks
  947. Mcl-1 Depletion In Apoptosis Elicited By Ionizing Radiation In Peritoneal Resident Macrophages Of C3H Mice
  948. Mcl-1 Depletion Sensitizes The Apoptosis Of Gastrointestinal Cancer Cells Mediated By Anti-Cancer Drugs.
  949. Mcl-1 Determines The Bax Dependency Of Nbk/Bik-Induced Apoptosis
  950. Mcl-1 Determines The Imiquimod-Induced Apoptosis But Not Imiquimod-Induced Autophagy In Skin Cancer Cells
  951. Mcl-1 Dictates Dna Double-Strand Break Repair Pathway Choice
  952. Mcl-1 Downregulation By Pro-Inflammatory Cytokines And Palmitate Is An Early Event Contributing Beta Cell Apoptosis.
  953. Mcl-1 Downregulation By Pro-Inflammatory Cytokines And Palmitate Is An Early Event Contributing To Β-Cell Apoptosis
  954. Mcl-1 Downregulation By Ym155 Contributes To Its Synergistic Anti-Tumor Activities With Abt-263
  955. Mcl-1 Downregulation Leads To The Heightened Sensitivity Exhibited By Bcr-Abl Positive All To Induction Of Energy And Er-Stress
  956. Mcl-1 Downregulation Plays A Crucial Role In The Synergistic Anticancer Activities Between Pi-3 Kinase Inhibitors And Histone Deacetylase Inhibitors In Primary Nsclc …
  957. Mcl-1 Down-Regulation Potentiates Abt-737 Lethality By Cooperatively Inducing Bak Activation And Bax Translocation
  958. Mcl-1 Downregulation Sensitizes Glioma To Bortezomib-Induced Apoptosis
  959. Mcl-1 Drives Resistance Of Estrogen Receptor-[Alpha] Positive Breast Cancers To Targeted Therapies
  960. Mcl-1 Dynamics Influence Mitotic Slippage And Death In Mitosis
  961. Mcl-1 Expression And Jnk Activation Induces A Threshold For Apoptosis In Bcl-Xl-Overexpressing Hematopoietic Cells
  962. Mcl-1 Expression Has In Vitro And In Vivo Significance In Chronic Lymphocytic Leukemia And Is Associated With Other Poor Prognostic Markers
  963. Mcl-1 Expression In B-Cell Non-Hodgkin’S Lymphomas
  964. Mcl‐1 Expression In Gestational Trophoblastic Disease Correlates With Clinical Outcome: A Differential Expression Study
  965. Mcl-1 Expression In Human Neutrophils: Regulation By Cytokines And Correlation With Cell Survival
  966. Mcl-1 Expression Influcences Cd8+ Anti-Tumor Immunity.
  967. Mcl-1 Expression Is Up-Regulated In Malignancies Of The Parotid Gland
  968. Mcl-1 Expression Of Non-Small Cell Lung Cancer As A Prognostic Factor And Mcl-1 As A Promising Target For Gene Therapy.
  969. Mcl-1 Expression Predicts Progression-Free Survival In Chronic Lymphocytic Leukemia Patients Treated With Pentostatin, Cyclophosphamide, And Rituximab
  970. Mcl-1 Facilitates Mitochondrial Fission And Clearance
  971. Mcl-1 Facilitates The Removal Of Damaged Mitochondria Via The Mitophagy Receptor Bnip3
  972. Mcl-1 Fragment Mcl-1 (128–350) Induces Inhibition Of Multiple Myeloma Cell Proliferation And Apoptosis Via Both Upregulation Of C-Jun As Well As Modulation Of Its …
  973. Mcl-1 Functions As Major Epidermal Survival Protein Required For Proper Keratinocyte Differentiation
  974. Mcl-1 Gene And Hepatocellular Carcinoma [J]
  975. Mcl-1 Gene And Its Role In Leukemia [J]
  976. Mcl-1 Gene Promoter Insertions Do Not Correlate With Disease Outcome, Stage Or Vh Gene Mutation Status In Chronic Lymphocytic Leukaemia
  977. Mcl-1 In Breast Cancer: Regulation By The Egf Receptor Family And Role In Cell Survival And Drug Resistance
  978. Mcl-1 In Transgenic Mice Promotes Survival In A Spectrum Of Hematopoietic Cell Types And Immortalization In The Myeloid Lineage
  979. Mcl-1 Inhibition Ameliorates The Expansion Of Human Leukemia In A Dose Dependent Fashion
  980. Mcl-1 Inhibition By Selective Bh3 Mimetics Disrupts Mitochondrial Dynamics In Ipsc-Derived Cardiomyocytes
  981. Mcl-1 Inhibition By The Selective Mcl-1 Inhibitor Amg-176 Induces In Vitro Activity Against Burkitt Lymphoma Cell Lines And Synergistically Enhances The Cytotoxic …
  982. Mcl-1 Inhibition In Cancer Treatment
  983. Mcl-1 Inhibition Provides A New Way To Suppress Breast Cancer Metastasis And Increase Sensitivity To Dasatinib
  984. Mcl-1 Inhibitor Induces Cells Death In Braf-Mutant Amelanotic Melanoma Trough Gsh Depletion, Dna Damage And Cell Cycle Changes
  985. Mcl-1 Inhibitor Suppresses Tumor Growth Of Esophageal Squamous Cell Carcinoma In A Mouse Model
  986. Mcl-1 Inhibitor-Induced Killing Of Multiple Myeloma Is Modulated By The Relative Level Of Expression Of Pro-Survival Members Of The Bcl-2 Family And The Proto …
  987. Mcl-1 Inhibitors For The Treatment Of Cancer
  988. Mcl-1 Inhibitors: A Patent Review
  989. Mcl-1 Inhibitors–Where Are We Now (2019)?
  990. Mcl-1 Inhibits Bax In The Absence Of Mcl-1/Bax Interaction
  991. Mcl-1 Inhibits Mff-Mediated Mitochondrial Fragmentation And Apoptosis
  992. Mcl-1 Integrates The Opposing Actions Of Signaling Pathways That Mediate Survival And Apoptosis
  993. Mcl-1 Interacts With Akt To Promote Lung Cancer Progression
  994. Mcl-1 Interacts With Truncated Bid And Inhibits Its Induction Of Cytochrome C Release And Its Role In Receptor-Mediated Apoptosis
  995. Mcl-1 Inversely Correlates With Gsk-3Β Activity And Associates With Poor Prognosis In Human Breast Cancer
  996. Mcl-1 Involvement In Mitochondrial Dynamics Is Associated With Apoptotic Cell Death
  997. Mcl-1 Involves In G_2/M Arrest Of Hl-60 Cells Induced By Diallyl Disulfide
  998. Mcl-1 Is A Common Target Of Stem Cell Factor And Interleukin-5 For Apoptosis Prevention Activity Via Mek/Mapk And Pi-3K/Akt Pathways
  999. Mcl-1 Is A Critical Survival Factor In Neural Precursor Cells Of The Adult Mammalian Brain
  1000. Mcl-1 Is A Gate Keeper Regulating Cell Death In Cancer Cells
  1001. Mcl-1 Is A Key Antiapoptotic Protein In Human And Rodent Pancreatic Β-Cells
  1002. Mcl-1 Is A Key Anti-Apoptotic Protein In Human And Rodent Pancreatic Β-Cells
  1003. Mcl-1 Is A Key Determinant Of Breast Cancer Cell Survival: Validation Of Mcl-1 Dependency Utilizing A Highly Selective Small Molecule Inhibitor
  1004. Mcl-1 Is A Key Regulator Of Apoptosis During Cns Development And After Dna Damage
  1005. Mcl-1 Is A Key Regulator Of Apoptosis In Neural Precursor Cells And Autophagy In Post-Mitotic Neurons
  1006. Mcl-1 Is A Key Regulator Of Apoptosis Resistance In Chlamydia Trachomatis-Infected Cells
  1007. Mcl-1 Is A Key Regulator Of The Ovarian Reserve
  1008. Mcl-1 Is A Novel Target Of Mir-26B That Is Associated With The Apoptosis Induced By Trail In Hcc Cells
  1009. Mcl-1 Is A Novel Therapeutic Target For Human Sarcoma: Synergistic Inhibition Of Human Sarcoma Xenotransplants By A Combination Of Mcl-1 Antisense Oligonucleotides …
  1010. Mcl-1 Is A Potential Therapeutic Target In Multiple Types Of Cancer
  1011. Mcl-1 Is A Prognostic Indicator And Drug Target In Breast Cancer
  1012. Mcl-1 Is A Relevant Molecular Target For Antisense Oligonucleotide Strategies In Gastric Cancer Cells
  1013. Mcl-1 Is A Relevant Therapeutic Target In Acute And Chronic Lymphoid Malignancies: Down-Regulation Enhances Rituximab-Mediated Apoptosis And Complement …
  1014. Mcl-1 Is A Stress Sensor That Regulates Autophagy In A Developmentally Regulated Fashion
  1015. Mcl‐1 Is A Stress Sensor That Regulates Autophagy In A Developmentally Regulated Manner
  1016. Mcl-1 Is An Anti-Apoptotic Factor For Human Hepatocellular Carcinoma
  1017. Mcl-1 Is An Immediate-Early Gene Activated By The Granulocyte-Macrophage Colony-Stimulating Factor (Gm-Csf) Signaling Pathway And Is One Component Of The Gm …
  1018. Mcl-1 Is An Important Determinant Of The Apoptotic Response To The Bh3-Mimetic Molecule Ha14-1 In Cisplatin-Resistant Ovarian Carcinoma Cells
  1019. Mcl-1 Is An Important Therapeutic Target For Oral Squamous Cell Carcinomas
  1020. Mcl-1 Is Critical For Survival In A Subgroup Of Non-Small-Cell Lung Cancer Cell Lines
  1021. Mcl-1 Is Differentially Regulated In Acute Myeloid Leukemia Cells Treated With All Trans Retinoic Acid And Arsenic Trioxide
  1022. Mcl-1 Is Downregulated In Cisplatin-Induced Apoptosis, And Proteasome Inhibitors Restore Mcl-1 And Promote Survival In Renal Tubular Epithelial Cells
  1023. Mcl-1 Is Essential For Germinal Center Formation And B Cell Memory
  1024. Mcl-1 Is Essential For Myocardial Homeostasis And Autophagy
  1025. Mcl-1 Is Essential For The Survival Of Plasma Cells
  1026. Mcl-1 Is Essential For The Survival Of Synovial Fibroblasts In Rheumatoid Arthritis
  1027. Mcl-1 Is Important For Integrity And Survival Of Hepatocytes
  1028. Mcl-1 Is Modulated In Crohn’S Disease Fibrosis By Mir-29B Via Il-6 And Il-8
  1029. Mcl-1 Is Overexpressed In Multiple Myeloma And Associated With Relapse And Shorter Survival
  1030. Mcl-1 Is Overexpressed In Multiple Myeloma And Correlates With Disease Severity.
  1031. Mcl-1 Is Regulated By Il-6 And Mediates The Survival Activity Of The Cytokine In A Model Of Late Stage Prostate Carcinoma
  1032. Mcl-1 Is Required For Akata6 B-Lymphoma Cell Survival And Is Converted To A Cell Death Molecule By Efficient Caspase-Mediated Cleavage
  1033. Mcl-1 Is Required For Melanoma Cell Resistance To Anoikis
  1034. Mcl-1 Is Required Throughout B-Cell Development And Its Loss Sensitizes Specific B-Cell Subsets To Inhibition Of Bcl-2 Or Bcl-Xl
  1035. Mcl-1 Is The Key Target Of Adjuvant Chemotherapy To Reverse The Cisplatin-Resistance In Nsclc
  1036. Mcl-1 Is Vital For Neutrophil Survival
  1037. Mcl-1 Keeps A Charming Home For Thymocytes
  1038. Mcl-1 Levels Need Not Be Lowered For Cells To Be Sensitized For Abt-263/737-Induced Apoptosis
  1039. Mcl-1 Localizes To Sites Of Dna Damage And Regulates Dna Damage Response
  1040. Mcl-1 Mediates Cytokine Deprivation Induced Apoptosis Of Human Myeloma Cell Line Xg-7.
  1041. Mcl-1 Mediates Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Resistance In Human Cholangiocarcinoma Cells
  1042. Mcl-1 Mediates Tweak/Fn14-Induced Non–Small Cell Lung Cancer Survival And Therapeutic Response
  1043. Mcl-1 Or Bcl-Xl-Dependent Resistance To The Bcl-2 Antagonist (Abt-199) Can Be Overcome By Specific Inhibitor As Single Agents And In Combination With Abt-199 In …
  1044. Mcl-1 Overexpression In Hepatocellular Carcinoma: A Potential Target For Antisense Therapy
  1045. Mcl‐1 Overexpression Leads To Higher Viabilities And Increased Production Of Humanized Monoclonal Antibody In Chinese Hamster Ovary Cells
  1046. Mcl-1 Phosphorylation Defines Abt-737 Resistance That Can Be Overcome By Increased Noxa Expression In Leukemic B Cells
  1047. Mcl-1 Phosphorylation Without Degradation Mediates Sensitivity To Hdac Inhibitors By Liberating Bh3-Only Proteins
  1048. Mcl-1 Promoter Insertions As An Independent Prognostic Factor For Treatment Free Survival In Chronic Lymphocytic Leukaemia.
  1049. Mcl-1 Promoter Insertions Dial-Up Aggressiveness Of Chronic Leukemia
  1050. Mcl-1 Promotes Drp1-Mediated Mitochondrial Fission As An Adaptive Response To Stress
  1051. Mcl–1 Promotes Drug Resistance In Pancreatic Cancer Cells
  1052. Mcl-1 Promotes Lung Cancer Cell Migration By Directly Interacting With Vdac To Increase Mitochondrial Ca 2+ Uptake And Reactive Oxygen Species Generation
  1053. Mcl-1 Promotes Mitochondrial Fusion And Survival In Cardiac Myocytes
  1054. Mcl-1 Promotes Neural Precursor Cell Cycle Exit And Differentiation In The Mouse Embryonic Brain
  1055. Mcl-1 Promotes Survival And Influences Mitochondrial Dynamics In Cardiac Myocytes
  1056. Mcl-1 Promotes Survival Of Thymocytes By Inhibition Of Bak In A Pathway Separate From Bcl-2
  1057. Mcl-1 Promotes T Cell Survival Independently Of Bcl-2 Through Interaction With Bak (84.19)
  1058. Mcl-1 Protects Prostate Cancer Cells From Cell Death Mediated By Chemotherapy-Induced Dna Damage
  1059. Mcl-1 Protects Prostate Cancer Cells From Chemotherapy-Induced Dna Damage
  1060. Mcl-1 Quadruplex Nucleic Acids And Uses Thereof
  1061. Mcl-1 Reduction: Releasing A Death Brake?
  1062. Mcl-1 Regulates Effector And Memory Cd8 T-Cell Differentiation During Acute Viral Infection
  1063. Mcl-1 Regulates Mitochondrial Dynamics And Mitophagy
  1064. Mcl-1 Regulates Mitochondrial Fission And Mitophagy
  1065. Mcl-1 Regulates Reactive Oxygen Species Via Nox4 During Chemotherapy-Induced Senescence
  1066. Mcl-1 Regulates Survival And Sensitivity To Diverse Apoptotic Stimuli In Human Non-Small Cell Lung Cancer Cells
  1067. Mcl-1 Regulates The Balance Between Autophagy And Apoptosis
  1068. Mcl-1 Regulates The Survival Of Adult Neural Precursor Cells
  1069. Mcl-1 Regulation And Its Role In Multiple Myeloma
  1070. Mcl-1 Rescues A Glitch In The Matrix
  1071. Mcl-1 Sequesters Pro-Apoptotic Bh3-Only Bim To Inhibit Its Collaboration With Bax In Myeloma Cells.
  1072. Mcl-1 Signals Pathway Inhibitors In Mouse Peritoneal Macrophage Apoptosis Infected With The Xinjiang Strain Of M. Tuberculosis
  1073. Mcl-1 Small-Molecule Inhibitors Encapsulated Into Nanoparticles Exhibit Increased Killing Efficacy Towards Hcmv-Infected Monocytes
  1074. Mcl-1 Stability Determines Mitotic Cell Fate Of Human Multiple Myeloma Tumor Cells Treated With The Kinesin Spindle Protein Inhibitor Arry-520
  1075. Mcl-1 Stabilization Confers Resistance To Taxol In Human Gastric Cancer
  1076. Mcl-1 Structural Dynamics From Protein Ensembles, Enhanced Sampling And Pocket Crosstalk Analysis.
  1077. Mcl-1 Suppresses Abasic Site Repair Following Bile Acid–Induced Hepatic Cellular Dna Damage
  1078. Mcl-1 Suppression Sensitizes Kras-Mutant Crc To Bcl-2/Bcl-Xl Inhibition
  1079. Mcl‐1 Targeting Could Be An Intriguing Perspective To Cure Cancer
  1080. Mcl-1 Ubiquitination And Destruction
  1081. Mcl-1 Ubiquitination: Unique Regulation Of An Essential Survival Protein
  1082. Mcl-1 Up-Regulation Through Mapk Activation Confers Acquired Resistance To Bcl-2 Inhibitor Abt-199 In Pre-Clinical Aml Models
  1083. Mcl-1, A Bcl-2 Family Member, Delays The Death Of Hematopoietic Cells Under A Variety Of Apoptosis-Inducing Conditions
  1084. Mcl-1, A Member Of The Bcl-2 Family, Delays Apoptosis Induced By C-Myc Overexpression In Chinese Hamster Ovary Cells
  1085. Mcl‐1, A Member Of The Bcl‐2 Family, Is Induced Rapidly In Response To Signals For Cell Differentiation Or Death, But Not To Signals For Cell Proliferation
  1086. Mcl-1, A Novel Target Gene Of Foxm1, Is Negatively Associated With Sensitivity To Oxaliplatin In Gastric Cancer
  1087. Mcl-1, An Anti-Apoptotic Bcl-2 Family Member, Essentially Overlaps With Insulin-Producing Cells In Neonatal Nesidioblastosis
  1088. Mcl-1, An Early-Induction Molecule, Modulates Activin A-Induced Apoptosis And Differentiation Of Cml Cells
  1089. Mcl-1, Bcl-Xl And Cell Cycle Inhibition By Gcs-100: A Novel Therapy For Myeloma.
  1090. Mcl-1, Bcl-Xl And Mitf Are Diversely Employed In Adaptive Response Of Melanoma Cells To Changes In Microenvironment
  1091. Mcl-1, Bcl-Xl And Stat3 Expression Are Associated With Progression Of Melanoma Whereas Bcl-2, Ap-2 And Mitf Levels Decrease During Progression Of …
  1092. Mcl-1, Vascular Endothelial Growth Factor-R2, And 14-3-3Σ Expression Might Predict Primary Response Against Radiotherapy And Chemotherapy In Patients With Locally …
  1093. Mcl-1, Which Can Prevent Leukemia Cell Death, Is Necessary For Bone Marrow Stem Cell Survival
  1094. Mcl-1/Cdk9 Targeting By Azd5991/Azd4573 Overcomes Intrinsic And Acquired Venetoclax Resistance In Vitro And In Vivo In Pdx Model Of Aml Through …
  1095. Mcl-1: A Gateway To Trail Sensitization
  1096. Mcl-1: A Highly Regulated Cell Death And Survival Controller
  1097. Mcl-1: The 1 In Cll
  1098. Mcl‐1; The Molecular Regulation Of Protein Function
  1099. Mcl‐1–Bim Complexes Accommodate Surprising Point Mutations Via Minor Structural Changes
  1100. Mcl-1-Dependent Activation Of Beclin 1 Mediates Autophagic Cell Death Induced By Sorafenib And Sc-59 In Hepatocellular Carcinoma Cells
  1101. Mcl-1–Dependent Leukemia Cells Are More Sensitive To Chemotherapy Than Bcl-2–Dependent Counterparts
  1102. Mcl-1Es, A Novel Variant Of Mcl-1, Associates With Mcl-1L And Induces Mitochondrial Cell Death
  1103. Mcl-1-Guardian Of The Ovarian Reserve: Characterization Of The Contribution Of Mcl-1 To Oocyte Survival
  1104. Mcl-1-Independent Mechanisms Of Synergy Between Dual Pi3K/Mtor And Bcl-2 Inhibition In Diffuse Large B Cell Lymphoma
  1105. Mcl-1—Just Another Antiapoptotic Bcl-2 Homolog?
  1106. Mcl-1-Mediated Impairment Of The Intrinsic Apoptosis Pathway In Circulating Neutrophils From Critically Ill Patients Can Be Overcome By Fas Stimulation
  1107. Mcl-1-Mediated Resistance To Abt-263 Is Combated By Mtor Inhibition In Luminal Breast Cancers
  1108. Mcl-1S, A Splicing Variant Of The Antiapoptotic Bcl-2 Family Member Mcl-1, Encodes A Proapoptotic Protein Possessing Only The Bh3 Domain
  1109. Mcl-1V, A Novel Mouse Antiapoptotic Mcl-1 Variant, Generated By Rna Splicing At A Non-Canonical Splicing Pair
  1110. Mechanism And Functional Role Of Xiap And Mcl-1 Down-Regulation In Flavopiridol/Vorinostat Antileukemic Interactions
  1111. Mechanism By Which Mcl-1 Regulates Cancer-Specific Apoptosis Triggered By Mda-7/Il-24, An Il-10–Related Cytokine
  1112. Mechanism Of Apoptosis Induced By Mcl-1 Inhibitor Umi-77 On Gallbladder Carcinoma Gbc-Sd Cells
  1113. Mechanism Of Mcl‐1 Conformational Regulation Upon Small Molecule Binding Revealed By Molecular Dynamic Simulation
  1114. Mechanism Of Synergy Of Bh3 Mimetics And Paclitaxel In Chronic Myeloid Leukemia Cells: Mcl-1 Inhibition
  1115. Mechanism Of Synergy Of N-(4-Hydroxyphenyl)Retinamide And Abt-737 In Acute Lymphoblastic Leukemia Cell Lines: Mcl-1 Inactivation
  1116. Mechanisms Involved In Interleukin‐15‐Induced Suppression Of Human Neutrophil Apoptosis: Role Of The Anti‐Apoptotic Mcl‐1 Protein And Several Kinases Including …
  1117. Mechanisms Of Ethanol‐Mediated Colorectal Carcinogenesis: The Role Of Cytochrome P4502E1, Etheno‐Dna Adducts, And The Anti‐Apoptotic Protein Mcl‐1
  1118. Mek Inhibition Enhances Abt-737-Induced Leukemia Cell Apoptosis Via Prevention Of Erk-Activated Mcl-1 Induction And Modulation Of Mcl-1/Bim Complex
  1119. Mek/Erk And Mcl-1 Inhibition Synergistically Reverse Apoptosis Resistance In Colon Cancer Cells With Braf (V600E)-Mediated Mcl-1-Upregulation
  1120. Mek/Erk Signaling Pathway Regulates The Expression Of Bcl‐2, Bcl‐Xl, And Mcl‐1 And Promotes Survival Of Human Pancreatic Cancer Cells
  1121. Melphalan-Induced Apoptosis In Multiple Myeloma Cells Is Associated With A Cleavage Of Mcl-1 And Bim And A Decrease In The Mcl-1/Bim Complex
  1122. Membrane Expression Of Dr4, Dr5 And Caspase-8 Levels, But Not Mcl-1, Determine Sensitivity Of Human Myeloma Cells To Apo2L/Trail
  1123. Mesothelin Confers Pancreatic Cancer Cell Resistance To Tnf-Α-Induced Apoptosis Through Akt/Pi3K/Nf-Κb Activation And Il-6/Mcl-1 Overexpression
  1124. Metformin Combined With Aspirin Significantly Inhibit Pancreatic Cancer Cell Growth In Vitro And In Vivo By Suppressing Anti-Apoptotic Proteins Mcl-1 And Bcl-2
  1125. Metformin Combined With Sodium Dichloroacetate Promotes B Leukemic Cell Death By Suppressing Anti-Apoptotic Protein Mcl-1
  1126. Metformin Enhances Trail-Induced Apoptosis By Mcl-1 Degradation Via Mule In Colorectal Cancer Cells
  1127. Metformin Requires 4E-Bps To Induce Apoptosis And Repress Translation Of Mcl-1 In Hepatocellular Carcinoma Cells
  1128. Methylseleninic Acid Potentiates Multiple Types Of Cancer Cells To Abt-737-Induced Apoptosis By Targeting Mcl-1 And Bad
  1129. Methylseleninic Acid Potentiates Multiple Types Of Cancer Cells To Abt-737-Induced Apoptosis Involving Mcl-1, Akt-Bad, And Mitochondrial Cascade
  1130. Microrna 133B Targets Pro-Survival Molecules Mcl-1 And Bcl2L2 In Lung Cancer
  1131. Microrna 17‐5P Regulates Autophagy In Mycobacterium Tuberculosis‐Infected Macrophages By Targeting Mcl‐1 And Stat3
  1132. Microrna Hsa-Mir-29B Potentiates Etoposide Toxicity In Hela Cells Via Down-Regulation Of Mcl-1
  1133. Microrna-101 Inhibits Cell Progression And Increases Paclitaxel Sensitivity By Suppressing Mcl-1 Expression In Human Triple-Negative Breast Cancer
  1134. Microrna-101 Sensitizes Hepatocellular Carcinoma Cells To Doxorubicin-Induced Apoptosis Via Targeting Mcl-1
  1135. Microrna-101 Targets Ezh2, Mcl-1 And Fos To Suppress Proliferation, Invasion And Stem Cell-Like Phenotype Of Aggressive Endometrial Cancer Cells
  1136. Microrna‐105 Promotes Epithelial‐Mesenchymal Transition Of Nonsmall Lung Cancer Cells Through Upregulating Mcl‐1
  1137. Microrna-125B Promotes Apoptosis By Regulating The Expression Of Mcl-1, Bcl-W And Il-6R
  1138. Microrna-133A, Downregulated In Osteosarcoma, Suppresses Proliferation And Promotes Apoptosis By Targeting Bcl-Xl And Mcl-1
  1139. Microrna-193B-3P Represses Neuroblastoma Cell Growth Via Downregulation Of Cyclin D1, Mcl-1 And Mycn
  1140. Microrna-30 Inhibits Antiapoptotic Factor Mcl-1 In Mouse And Human Hematopoietic Cells After Radiation Exposure
  1141. Microrna-302B Enhances The Sensitivity Of Hepatocellular Carcinoma Cell Lines To 5-Fu Via Targeting Mcl-1 And Dpyd
  1142. Microrna-302B Targets Mcl-1 And Inhibits Cell Proliferation And Induces Apoptosis In Malignant Pleural Mesothelioma Cells
  1143. Microrna-451 Sensitizes Lung Cancer Cells To Cisplatin Through Regulation Of Mcl-1
  1144. Mik665/S64315, A Novel Mcl-1 Inhibitor, In Combination With Bcl-2 Inhibitors Exhibits Strong Synergistic Antitumor Activity In A Range Of Hematologic Malignancies
  1145. Mim1, The Mcl-1–Specific Bh3 Mimetic Induces Apoptosis In Human U87Mg Glioblastoma Cells
  1146. Mir-101 And Mcl-1 In Non-Small-Cell Lung Cancer: Expression Profile And Clinical Significance
  1147. Mir-101 Synergistically Enhances Abt-737 Mediated Apoptosis Through Inhibition Of Mcl-1 Expression In Non-Small Cell Lung Cancer
  1148. Mir-106A Targets Mcl-1 To Suppress Cisplatin Resistance Of Ovarian Cancer A2780 Cells
  1149. Mir-137 And Mir-197 Induce Apoptosis And Suppress Tumorigenicity By Targeting Mcl-1 In Multiple Myeloma
  1150. Mir-137 And Mir-197 Within Chromosome 1P Minimal Deletion Region Regulate Apoptotic Activity In Multiple Myeloma By Targeting Mcl 1
  1151. Mir‐139 Inhibits Mcl‐1 Expression And Potentiates Tmz‐Induced Apoptosis In Glioma
  1152. Mir-153 Regulates Apoptosis And Autophagy Of Cardiomyocytes By Targeting Mcl-1
  1153. Mir181 Regulates Mcl-1 Expression In Lyn-Dependent Imatinib-Resistant Cml
  1154. Mir‑181B Increases Drug Sensitivity In Acute Myeloid Leukemia Via Targeting Hmgb1 And Mcl-1
  1155. Mir-193B Modulates Resistance To Doxorubicin In Human Breast Cancer Cells By Downregulating Mcl-1
  1156. Mir-193B Regulates Mcl-1 In Melanoma
  1157. Mir-205 And Mir-218 Expression Is Associated With Carboplatin Chemoresistance And Regulation Of Apoptosis Via Mcl-1 And Survivin In Lung Cancer Cells
  1158. Mir-22 And Mir-29A Are Members Of The Androgen Receptor Cistrome Modulating Lamc1 And Mcl-1 In Prostate Cancer
  1159. Mir-26A Inhibits Proliferation And Migration Of Breast Cancer Through Repression Of Mcl-1
  1160. Mir-29 Regulates Mcl-1 Protein Expression And Apoptosis
  1161. Mir-29A Down-Regulation In Alk-Positive Anaplastic Large Cell Lymphomas Contributes To Apoptosis Blockade Through Mcl-1 Overexpression
  1162. Mir-29A Promotes Intestinal Epithelial Apoptosis In Ulcerative Colitis By Down-Regulating Mcl-1
  1163. Mir‑29B Affects Neurocyte Apoptosis By Targeting Mcl‑1 During Cerebral Ischemia/Reperfusion Injury
  1164. Mir-29B And Mir-198 Overexpression In Cd8+ T Cells Of Renal Cell Carcinoma Patients Down-Modulates Jak3 And Mcl-1 Leading To Immune Dysfunction
  1165. Mir-363 Sensitizes Cisplatin-Induced Apoptosis Targeting In Mcl-1 In Breast Cancer
  1166. Mir-519D Impedes Cisplatin-Resistance In Breast Cancer Stem Cells By Down-Regulating The Expression Of Mcl-1
  1167. Mir-9 Enhances The Chemosensitivity Of Aml Cells To Daunorubicin By Targeting The Eif5A2/Mcl-1 Axis
  1168. Mirna-29B Targets Mcl-1 And Is Down-Regulated In Chemotherapy-Resistant Acute Myeloid Leukemia (Aml).
  1169. Mirna98 Induces Apoptosis Of Hcc827 Cell Via Downregulation Of Mcl-1
  1170. Mithramycin A Induces Apoptosis By Regulating The Mtor/Mcl-1/Tbid Pathway In Androgen-Independent Prostate Cancer Cells
  1171. Mitochondria-Independent Cytotoxic Effect Of Nelfinavir On Leukemia Cells Can Be Enhanced By Sorafenib-Mediated Mcl-1 Downregulation And Mitochondrial …
  1172. Mitochondrion-Dependent N-Terminal Processing Of Outer Membrane Mcl-1 Protein Removes An Essential Mule/Lasu1 Protein-Binding Site
  1173. Mitotic Arrest And Jnk-Induced Proteasomal Degradation Of Flip And Mcl-1 Are Key Events In The Sensitization Of Breast Tumor Cells To Trail By …
  1174. Mitotic Arrest-Induced Phosphorylation Of Mcl-1 Revisited Using Two-Dimensional Gel Electrophoresis And Phosphoproteomics: Nine Phosphorylation Sites …
  1175. Ml311: A Small Molecule That Potently And Selectively Disrupts The Protein-Protein Interaction Of Mcl-1 And Bim: A Probe For Studying Lymphoid Tumorigenesis
  1176. Modification Of Alternative Splicing Of Mcl-1 Pre-Mrna Using Antisense Morpholino Oligonucleotides Induces Apoptosis In Basal Cell Carcinoma Cells
  1177. Modification Of Bcl-X And Mcl-1 Pre-Mrna Splicing Using Splice-Switching Oligonucleotides
  1178. Modulation Of Akt, Erk And Mcl-1 By Apigenin Sensitizes Colon Cancer Cells To Anti-Tumor Activities Of Abt263.
  1179. Modulation Of Apoptosis By Berberine Through Inhibition Of Cyclooxygenase-2 And Mcl-1 Expression In Oral Cancer Cells
  1180. Modulation Of Mcl-1 Expression Reduces Age-Related Cochlear Degeneration
  1181. Modulation Of Mcl-1 Sensitizes Glioblastoma To Trail-Induced Apoptosis
  1182. Modulation Of Mcl-1 Transcription By Serum Deprivation Sensitizes Cancer Cells To Cisplatin
  1183. Modulation Of Navitoclax Sensitivity By Dihydroartemisinin-Mediated Mcl-1 Repression In Bcr-Abl+ B-Lineage Acute Lymphoblastic Leukemia
  1184. Modulation Of Noxa And Mcl-1 As A Strategy For Sensitizing Melanoma Cells To The Bh3-Mimetic Abt-737
  1185. Modulator Of Apoptosis (Puma) Chemosensitizes Intrinsically Resistant Ovarian Cancer Cells To Cisplatin By Lowering The Threshold Set By Bcl-X L And Mcl-1
  1186. Molecular Cloning Of Canine Mcl-1 Gene And Its Expression In Tumor Cell Lines
  1187. Molecular Comprehension Of Mcl-1: From Gene Structure To Cancer Therapy
  1188. Molecular Docking Studies Of Anti-Apoptotic Bcl-2, Bcl-Xl, And Mcl-1 Proteins With Ginsenosides From Panax Ginseng
  1189. Molecular Docking Studies Of Bioactive Compounds From Annona Muricata Linn As Potential Inhibitors For Bcl-2, Bcl-W And Mcl-1 Antiapoptotic Proteins
  1190. Molecular Dynamics Study Of Segment Peptides Of Bax, Bim, And Mcl-1 Bh3 Domain Of The Apoptosis-Regulating Proteins Bound To The Anti-Apoptotic Mcl-1 Protein
  1191. Monoclonal Antibody Induces Apoptosis In Chronic Lymphocytic Leukemia B Cells By Downregulating Mcl-1 And Upregulating Bim
  1192. Monosaccharide Digitoxin Derivative Sensitize Human Non-Small Cell Lung Cancer Cells To Anoikis Through Mcl-1 Proteasomal Degradation
  1193. Most Putative Bh3 Mimetics Preferentially Antagonize The Anti-Apoptotic Protein Mcl-1 Rather Than Bcl-2
  1194. Mouse Noxa Uses Only The C-Terminal Bh3-Domain To Inactivate Mcl-1
  1195. Mpt0B169, A Novel Tubulin Inhibitor, Induces Apoptosis In Taxol-Resistant Acute Myeloid Leukemia Cells Through Mitochondrial Dysfunction And Mcl-1 Downregulation
  1196. Mtor Complex 2 (Mtorc2) Positively Regulates Mcl-1 Stability By Suppressing Gsk3-Dependent And Fbxw7-Mediated Proteasomal Degradation Of Mcl-1
  1197. Mtor Complex 2 Stabilizes Mcl-1 Protein By Suppressing Its Glycogen Synthase Kinase 3-Dependent And Scf-Fbxw7-Mediated Degradation
  1198. Mtor Inhibition Specifically Sensitizes Colorectal Cancers With Kras Or Braf Mutations To Bcl-2/Bcl-Xl Inhibition By Suppressing Mcl-1
  1199. Mtorc1 Activity Contributes To The Mcl-1 Dependence Of Her2 Amplified Breast Cancer Cells.
  1200. Mtorc1 Hyperactivity Inhibits Serum Deprivation Apoptosis Via Increased Hkii And Glut1 Expression, Sustained Mcl-1 Expression, And Gsk3Β Inhibition
  1201. Mtorc1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis Via Increased Hexokinase Ii And Glut1 Expression, Sustained Mcl-1 Expression, And Glycogen …
  1202. Mtorc1 Promotes Survival Through Translational Control Of Mcl-1
  1203. Muc1-C Stabilizes Mcl-1 In The Oxidative Stress Response Of Triple-Negative Breast Cancer Cells To Bcl-2 Inhibitors
  1204. Mule/Arf-Bp1, A Bh3-Only E3 Ubiquitin Ligase, Catalyzes The Polyubiquitination Of Mcl-1 And Regulates Apoptosis
  1205. Mule: Mcl-1 Ubiquitination Ligase E3
  1206. Multiple Mechanisms Of Mcl-1 Depletion By The Cyclin-Dependent Kinase Inhibitor Flavopiridol In Mantle Cell Lymphoma Cell Lines
  1207. Multiple Myeloma Induces Mcl-1 Expression And Survival Of Myeloid-Derived Suppressor Cells
  1208. Multiple Myeloma With 1Q21 Amplification Is Highly Sensitive To Mcl-1 Targeting
  1209. Multiple Myeloma With Amplification Of Chromosome 1Q Is Highly Sensitive To Mcl-1 Targeting
  1210. Multi-Walled Carbon Nanotubes Induce Apoptosis In Normal Human Small Airway Epithelial Cells Through Proteasome-Mediated Mcl-1 Protein Degradation
  1211. Mutant Braf Upregulates Mcl-1 To Confer Apoptosis Resistance That Is Reversed By Mcl-1 Antagonism And Cobimetinib In Colorectal Cancer
  1212. Mutant Braf Upregulates Mcl-1 To Confer Apoptosis Resistance That Is Reversed By Mcl-1 Antagonism And Cobimetinib In Colorectal Cancer.
  1213. Mutant B-Raf-Mcl-1 Survival Signaling Depends On The Stat3 Transcription Factor
  1214. Mutual Activities Of Iex-1 And Mcl-1 On The Apoptosis Of Ovarian Cancer Cells
  1215. Myc Induces Acute Myeloid Leukemia By Conferring Self-Renewal Activity To Committed Myeloid Progenitor Cells That Resist Apoptosis Via Endogenous Mcl-1.
  1216. Myc-Dependent Pi3K And Mcl-1 Feedbacks Attenuate Bet Inhibitors Activity In Diffuse Large B-Cell Lymphoma
  1217. Myeloid Cell Leukemia 1 (Mcl−1) Protects Against 1-Methyl-4-Phenylpyridinium Ion (Mpp+) Induced Apoptosis In Parkinson’S Disease
  1218. Myeloid Cell Leukemia 1 (Mcl-1), An Unexpected Modulator Of Protein Kinase Signaling During Invasion
  1219. Myeloid Cell Leukemia-1 (Mcl-1) Sirna Therapy Showed Cytotoxic Effect On T Cells Acute Lymphoblastic Leukemia
  1220. Myeloid-Specific Deletion Of Mcl-1 Yields Severely Neutropenic Mice That Survive And Breed In Homozygous Form
  1221. Myeloma Exhibits Dependence On Atypical Glucose Transporters: Targeting Mcl-1 Through Glut4 Inhibition
  1222. Nap1L1 Regulates Nf-Κb Signaling Pathway Acting On Anti-Apoptotic Mcl-1 Gene Expression
  1223. Nbk/Bik Antagonizes Mcl-1 And Bcl-X
  1224. Nbk/Bik Antagonizes Mcl-1 And Bcl-Xl And Activates Bak-Mediated Apoptosis In Response To Protein Synthesis Inhibition
  1225. Ndrg2 Contributes To Cisplatin Sensitivity Through Modulation Of Bak-To-Mcl-1 Ratio
  1226. Nedaplatin Enhanced Apoptotic Effects Of Abt-737 In Human Cancer Cells Via Mcl-1 Inhibition
  1227. Nelfinavir Induces Mitochondria Protection By Erk1/2-Mediated Mcl-1 Stabilization That Can Be Overcome By Sorafenib
  1228. Neuroprotective Effect Of G14-Humanin On Global Cerebral Ischemia/Reperfusion By Activation Of Socs3 – Stat3 – Mcl–1 Signal Transduction Pathway In Rats
  1229. Neutralization Of The Transcription Factor Nuclear Factor Erythroid Derived-2 (Nf-E2) Causes Robust Increases In The Anti-Apoptotic Protein Mcl-1 In Human Neutrophils
  1230. New Chemical Tools For Disrupting The Mcl-1/Bh3 Protein-Protein Interaction
  1231. New Face Of Antiapoptotic Proteins. I. Protein Mcl-1
  1232. Nf-Κb Activation Fails To Protect Cells To Tnfα-Induced Apoptosis In The Absence Of Bcl-Xl, But Not Mcl-1, Bcl-2 Or Bcl-W
  1233. Nf-Κb And Mcl-1 Are Important Determinants For The Effectiveness Of Bortezomib In Cd34+ Aml Versus Cd34− Aml Cells
  1234. Nf-Κb Is Active In Mcl-1 Promoter Regulation In Human Cll.
  1235. Nfκb Signaling And Mcl-1 Are Critical In B Cell Maturation Antigen-Promoted Multiple Myeloma Cell Growth And Survival
  1236. Nicotine Enhances The Antiapoptotic Function Of Mcl-1 Through Phosphorylation
  1237. Nicotine Induces Cell Survival And Chemoresistance By Stimulating Mcl‐1 Phosphorylation And Its Interaction With Bak In Lung Cancer
  1238. Nicotine Upregulates The Level Of Mcl-1 Through Stat3 In H1299 Cells
  1239. Nitidine Chloride Represses Mcl‐1 Protein Via Lysosomal Degradation In Oral Squamous Cell Carcinoma
  1240. Nkg2D Induces Mcl-1 Expression And Mediates Survival Of Cd8 Memory T Cell Precursors Via Phosphatidylinositol 3-Kinase
  1241. Nkg2D Induces Mcl-1 Expression And Mediates Survival Of Cd8 Memory T Cell Precursors Via Pi3K
  1242. Norcantharidin Enhances Abt-737-Induced Apoptosis In Hepatocellular Carcinoma Cells By Transcriptional Repression Of Mcl-1
  1243. Norcantharidin Induces Mitochondrial-Dependent Apoptosis Through Mcl-1 Inhibition In Human Prostate Cancer Cells
  1244. Notch Signaling Regulates Expression Of Mcl-1 And Apoptosis In Ppd-Treated Macrophages
  1245. Notch Signaling Sustains The Expression Of Mcl-1 And The Activity Of Eif4E To Promote Cell Survival In Cll
  1246. Notch1 Represses Mcl-1 Levels In Gsi-Resistant T-All, Making Them Susceptible To Abt-263
  1247. Notch1 Signaling Promotes Survival Of Glioblastoma Cells Via Egfr-Mediated Induction Of Anti-Apoptotic Mcl-1
  1248. Novel Cyclin Dependent Kinase (Cdk) Inhibitors Induce Down Regulation Of Mcl-1 And Apoptosis In Multiple Myeloma Cells
  1249. Novel Functions Of Mcl-1 In Atm Signalling, Homologous Recombination, And Heterochromatin Dynamics
  1250. Novel Mcl-1 Inhibitor Effectively Restores In Vivo Regorafenib Sensitivity In Resistant Colorectal Cancer
  1251. Novel Mcl‐1/Bcl‐2 Dual Inhibitors Created By The Structure‐Based Hybridization Of Drug‐Divided Building Blocks And A Fragment Deconstructed From A Known Two …
  1252. Novel Molecular Therapy Targeting Mcl-1 And Modulating Autophagy In Castration-Resistant Prostate Cancer
  1253. Novel Post-Transcriptional And Post-Translational Regulation Of Pro-Apoptotic Protein Bok And Anti-Apoptotic Protein Mcl-1 Determine The Fate Of Breast Cancer …
  1254. Novel Soluble Myeloid Cell Leukemia Sequence 1 (Mcl-1) Inhibitor (E, E)-2-(Benzylaminocarbonyl)-3-Styrylacrylonitrile (4G) Developed Using A Fragment-Based …
  1255. Novel Tyrosine Kinase Inhibitor Exel-0862 Induces Apoptosis In Human Fip1L1-Pdgfr-Α-Expressing Cells Through Caspase-3-Mediated Cleavage Of Mcl-1
  1256. Nox4-Mediated Ros Production Induces Apoptotic Cell Death Via Down-Regulation Of C-Flip And Mcl-1 Expression In Combined Treatment With Thioridazine And …
  1257. Noxa Controls Mule-Dependent Mcl-1 Ubiquitination Through The Regulation Of The Mcl-1/Usp9X Interaction
  1258. Noxa Determines Localization And Stability Of Mcl-1 And Consequently Abt-737 Sensitivity In Small Cell Lung Cancer
  1259. Noxa Induces Apoptosis In Oncogene-Expressing Cells Through Catch-And-Release Mechanism Operating Between Puma And Mcl-1
  1260. Noxa Up-Regulation And Mcl-1 Cleavage Are Associated To Apoptosis Induction By Bortezomib In Multiple Myeloma
  1261. Noxa, A Sensor Of Proteasome Integrity, Is Degraded By 26S Proteasomes By An Ubiquitin-Independent Pathway That Is Blocked By Mcl-1
  1262. Noxa/Mcl-1 Balance Influences The Effect Of The Proteasome Inhibitor Mg-132 In Combination With Anticancer Agents In Pancreatic Cancer Cell Lines
  1263. Noxa/Mcl-1 Balance Regulates Susceptibility Of Cells To Camptothecin-Induced Apoptosis
  1264. Npm-Alk Regulated Gsk3Β Phosphorylation Results In Mcl-1 And Cdc25A Accumulation And Enhanced Oncogenic Potential
  1265. Nuclear Topography Of The 1Q21 Genomic Region And Mcl-1 Protein Levels Associated With Pathophysiology Of Multiple Myeloma
  1266. Nucleoside Analog Arc Targets Mcl-1 To Induce Apoptosis In Leukemia Cells
  1267. Nvp-Bez235-Induced Apoptosis In Human Renal Carcinoma Caki Cells Through Down-Regulation Of P53-Dependent Bcl-2 Expression And Inhibition Of Mcl-1 …
  1268. Obatoclax (Gx15-070) Is A Potent Antagonist Of Constitutive Mcl-1/Bak Interactions In Intact Mitochondrial Membrane And Synergizes With Bortezomib In Mantle Cell …
  1269. Obatoclax Is A Direct And Potent Antagonist Of Membrane-Restricted Mcl-1 And Is Synthetic Lethal With Treatment That Induces Bim
  1270. Obesity And Il-6 Promote Liver Carcinogenesis Via Mcl-1 Stabilization
  1271. Obesity Promotes Liver Carcinogenesis Via Mcl-1 Stabilization Independent Of Il-6Rα Signaling
  1272. Obligate Role Of Anti-Apoptotic Mcl-1 In The Survival Of Hematopoietic Stem Cells
  1273. Observation On The Antisense Mcl-1 Transfected Malignant Melanoma Cells By Light Microscope And Electron Microscope
  1274. Occurs By A Mechanism Involving The Activation Of Pro-Apoptotic Bcl-2 Proteins Bak And Bid And The Inactivation Of Anti-Apoptotic Bcl-2 Proteins Bcl-Xl And Mcl-1
  1275. Of Adult Rat Germ Cell Death After Exposure To Xenoestrogens: Role Of Microrna Mir-29 Family In The Down-Regulation Of Dna Methyltransferases And Mcl-1
  1276. Of Cd44, A Receptor For Extracellular Matrix Components, Protects Chronic Lymphocytic Leukemia Cells From Spontaneous And Drug Induced Apoptosis Through Mcl-1
  1277. Of Docetaxel-Induced Cytotoxicity And Apoptosis By All-Trans Retinoic Acid (Atra) Through Downregulation Of Survivin (Birc5), Mcl-1 And Ltbeta-R In …
  1278. Of Marinopyrrole A (Maritoclax) As A Selective Mcl-1 Antagonist That Overcomes Abt-737 Resistance By Binding To And Targeting Mcl-1 For Proteasomal Degradation
  1279. Of Mcl-1 As A Novel Target In Neoplastic Mast Cells And Demonstration Of Cooperative Growth-Inhibitory Effects Of Mcl-1 Antisense Oligonucleotides, Pkc412, And …
  1280. Of Nf-Κb-Regulated Balance Of Anti-Apoptotic And Pro-Apoptotic Activity By Controlling Transcription And Cleavage Of Mcl-1
  1281. Of The Bcl-2 Inhibitor Abt199 (Venetoclax) In Bcl-2 High-Expressing Neuroblastoma Cell Lines And Xenografts And Rational For Combination With Mcl-1 …
  1282. Of The Human Mcl-1 Gene Encoding An Anti-Apoptotic Member Of The Bcl-2 Family: The Role Of Sp1 And Of Basic Transcription Factor Binding Sites In The Mcl-1 …
  1283. Of The Mtorc1/Torc2 Inhibitor Ink128 And The Bcl-2/Bcl-Xl Antagonist Abt-737 Kills Human Myeloid Leukemia Cells Through Mcl-1 Down-Regulation And Akt …
  1284. Of Xpo1 By Kpt-330 (Selinexor) Enhances Cell Death Induced By The Bcl-2 Selective Inhibitor Abt-199 (Venetoclax) Through Downregulation Of Mcl-1 In Acute Myeloid …
  1285. Omacetaxine May Have A Role In Chronic Myeloid Leukaemia Eradication Through Downregulation Of Mcl-1 And Induction Of Apoptosis In Stem/Progenitor Cells
  1286. Oncostatin M-Dependent Mcl-1 Induction Mediated By Jak1/2-Stat1/3 And Creb Contributes To Bioenergetic Improvements And Protective Effects Against …
  1287. Opposing Mcl-1, The Galig Proapoptotic Gene Is Upregulated As Neutrophils Die And Underexpressed In Acute Myeloid Leukemia Cells
  1288. Optimal Targeting Of Bcl-Family Proteins In Head And Neck Squamous Cell Carcinoma Requires Inhibition Of Both Bcl-Xl And Mcl-1
  1289. Or In A Supportive Microenvironment And Is Synergistic With Fludarabine In A Mechanism That Involves Decreased Levels Of Reactive Oxygen Species And Mcl-1 …
  1290. Ouabain Downregulates Mcl-1 And Sensitizes Lung Cancer Cells To Trail-Induced Apoptosis
  1291. Ovarian Cancer Ascites Increase Mcl-1 Expression In Tumor Cells Through Erk1/2-Elk-1 Signaling To Attenuate Trail-Induced Apoptosis
  1292. Overcomes Resistance Of Hepatocellular Carcinomas Against Chemotherapy And Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand By Elimination Of Mcl-1
  1293. Overcoming Acquired Resistance To Azd9291, A Third-Generation Egfr Inhibitor, Through Modulation Of Mek/Erk-Dependent Bim And Mcl-1 Degradation
  1294. Overcoming Chemoresistance In Pancreatic Cancer By Targeting The Anti-Apoptotic Mcl-1 Protein
  1295. Overexpression Of Anti‐Apoptotic Mcl‐1 In Testicular Germ Cell Tumours
  1296. Overexpression Of Mcl-1 Attenuates Liver Injury And Fibrosis In The Bile Duct–Ligated Mouse
  1297. Overexpression Of Mcl-1 Confers Multidrug Resistance, Whereas Topoisomerase Iiβ Downregulation Introduces Mitoxantrone-Specific Drug Resistance In Acute Myeloid …
  1298. Overexpression Of Mcl-1 Confers Resistance To Brafv600E Inhibitors Alone And In Combination With Mek1/2 Inhibitors In Melanoma
  1299. Overexpression Of Mcl-1 Exacerbates Lymphocyte Accumulation And Autoimmune Kidney Disease In Lpr Mice
  1300. Over-Expression Of Mcl-1 Impairs The Ability Of Atra To Induce Growth Arrest And Differentiation In Acute Promyelocytic Leukemia Cells
  1301. Overexpression Of Mcl-1 In Anaplastic Large Cell Lymphoma Cell Lines And Tumors
  1302. Overexpression Of Microrna-29B Induces Apoptosis Of Multiple Myeloma Cells Through Down Regulating Mcl-1
  1303. Overexpression Of Mir-101 Promotes Trail-Induced Mitochondrial Apoptosis In Papillary Thyroid Carcinoma By Targeting C-Met And Mcl-1
  1304. Overexpression Of P-Stat3 And Mcl-1, And Their Correlation With Differentiation And Apoptotic Resistance In Esophageal Squamous Cell Carcinoma
  1305. Overexpression Of The Anti-Apoptotic Genes Mcl-1, Bcl-W, Bcl-Xl And A1 Is Correlated With Chronic Myelogenous Leukemia Progression And Resistance To Gleevec.
  1306. P32, A Novel Binding Partner Of Mcl-1, Positively Regulates Mitochondrial Ca2+ Uptake And Apoptosis
  1307. P38 Mapk Controls Sensitivity Towards Bh3 Mimetics By Regulating Mcl-1 Expression Of Chronic Lymphocytic Leukemia In Hypoxia And Acquired Resistance
  1308. P53-Dependent Regulation Of Mcl-1 Contributes To Synergistic Cell Death By Ionizing Radiation And The Bcl-2/Bcl-Xl Inhibitor Abt-737
  1309. Paclitaxel In Combination With At-101 Induces Apoptosis Via Supressing Bcl-2, Bcl-Xl, Mcl-1 Proteins In Human Breast Cancer Cells.
  1310. Pan-Mammalian Target Of Rapamycin (Mtor) Inhibitor Azd8055 Primes Rhabdomyosarcoma Cells For Abt-737-Induced Apoptosis By Down-Regulating Mcl-1 Protein
  1311. Parkin Sensitizes Toward Apoptosis Induced By Mitochondrial Depolarization Through Promoting Degradation Of Mcl-1
  1312. Parkin-Dependent Degradation Of The F-Box Protein Fbw7Β Promotes Neuronal Survival In Response To Oxidative Stress By Stabilizing Mcl-1
  1313. Pathways In Cutaneous Squamous Cell Carcinoma Cells By Diclofenac/Hyaluronic Acid Is Related To Upregulation Of Bad As Well As Downregulation Of Mcl‐1 And Bcl‐W
  1314. Paxillin Confers Resistance To Tyrosine Kinase Inhibitors In Egfr-Mutant Lung Cancers Via Modulating Bim And Mcl-1 Protein Stability
  1315. Pcna And Anti-Apoptotic Mcl-1 Proteins Predict Disease-Free Survival In Oral Cancer Patients Treated With Definitive Radiotherapy
  1316. Pdgf Regulation Of Mcl-1 Expression In Bone-Metastatic Human Prostate Cancer Cells
  1317. Pdgf Upregulates Mcl-1 Through Activation Of Β-Catenin And Hif-1Α-Dependent Signaling In Human Prostate Cancer Cells
  1318. Pemetrexed Exerts Anticancer Effects By Inducing G0/G1‑Phase Cell Cycle Arrest And Activating The Noxa/Mcl‑1 Axis In Human Esophageal Squamous Cell …
  1319. Persistent Hepatitis C Virus (Hcv) Infection Impairs Hcv‐Specific Cytotoxic T Cell Reactivity Through Mcl‐1/Bim Imbalance Due To Cd127 Down‐Regulation
  1320. Persistent Mcl-1/Bim Protein Signature After Cd40 Ligation In Chronic Lymphocytic Leukemia Is Associated With Specific Drug Sensitivity
  1321. Phenylethyl Isothiocyanate Reverses Cisplatin Resistance In Biliary Tract Cancer Cells Via Glutathionylation-Dependent Degradation Of Mcl-1
  1322. Phosphatidylinositol 3-Kinase And P38 Mitogen-Activated Protein Kinase Regulate Induction Of Mcl-1 And Survival In Glucocorticoid-Treated Human Neutrophils
  1323. Phosphorylated Bcl-2 And Mcl-1 As Prognostic Markers In Small Cell Lung Cancer
  1324. Phosphorylation Alters Bim‐Mediated Mcl‐1 Stabilization And Priming
  1325. Phosphorylation Of Mcl‐1 By Cdk1–Cyclin B1 Initiates Its Cdc20‐Dependent Destruction During Mitotic Arrest
  1326. Photocatalytic Proximity Labelling Of Mcl-1 By A Bh3 Ligand
  1327. Phytosterols And Triterpenes From Morinda Lucida Benth (Rubiaceae) As Potential Inhibitors Of Anti-Apoptotic Bcl-Xl, Bcl-2, And Mcl-1: An In-Silico Study
  1328. Pi3K And Bcl-2 Inhibition Primes Glioblastoma Cells To Apoptosis Through Downregulation Of Mcl-1 And Phospho-Bad
  1329. Pi3K And P38 Mapk Regulate Induction Of Mcl-1 And Survival In Glucocorticoid Treated Human Neutrophils
  1330. Pi3K/Mtor Dual Inhibitor Nvp-Bez235 Decreases Mcl-1 Expression And Sensitizes Ovarian Carcinoma Cells To Bcl-Xl-Targeting Strategies, Provided That Bim …
  1331. Pi3K/Mtor Inhibition Markedly Potentiates Hdac Inhibitor Activity In Nhl Cells Through Bim-And Mcl-1–Dependent Mechanisms In Vitro And In Vivo
  1332. Pi3K-Dependent Upregulation Of Mcl-1 By Human Cytomegalovirus Is Mediated By Epidermal Growth Factor Receptor And Inhibits Apoptosis In Short-Lived Monocytes
  1333. Pik3Ca Mutations Enable Targeting Of A Breast Tumor Dependency Through Mtor-Mediated Mcl-1 Translation
  1334. Pk11195, A Mitochondrial Benzodiazepine Receptor Antagonist, Reduces Apoptosis Threshold In Bcl-Xl And Mcl-1 Expressing Human Cholangiocarcinoma Cells
  1335. Plasticity Of Bh3 Domain-Binding Hydrophobic Grooves In The Anti-Apoptotic Mcl-1 And A1 Proteins
  1336. Platinum Compounds Sensitize Ovarian Carcinoma Cells To Abt-737 By Modulation Of The Mcl-1/Noxa Axis
  1337. Platinum Sensitize Ovarian Carcinoma Cells To Abt-737 In Vitro And Ex Vivo Through Inhibition Of Mcl-1
  1338. Po-061 Bcl-2 Family Of Proteins, Bcl-Xl And Mcl-1, Regulate Apoptosis And Cancer Cell Survival By Different Mechanisms
  1339. Polymeric Delivery Of Sirna For Dual Silencing Of Mcl-1 And P-Glycoprotein And Apoptosis Induction In Drug-Resistant Breast Cancer Cells
  1340. Polymeric Micelles For Mcl-1 Gene Silencing In Breast Tumors Following Systemic Administration
  1341. Polymorphisms In The Promoter Region Of The Mcl-1 Gene Are Associated With Ex Vivo Cytotoxicity But Not With Response To Treatment In Advanced Chronic …
  1342. Potent And Selective Small-Molecule Mcl-1 Inhibitors Demonstrate On-Target Cancer Cell Killing Activity As Single Agents And In Combination With Abt-263 …
  1343. Potent Efficacy Of Mcl-1 Inhibitor-Based Therapies In Preclinical Models Of Mantle Cell Lymphoma
  1344. Potential Pharmacological Chaperones Targeting Cancer-Associated Mcl-1 And Parkinson Disease-Associated Α-Synuclein
  1345. Potently Increases The Sensitivity Of Resistant Acute Myeloid Leukemia Lines To The Bcl-2 Inhibitor Venetoclax By Mediating A Reduction In Cellular Mcl-1 Levels
  1346. Pparγ Is Critical For Mycobacterium Tuberculosis Induction Of Mcl-1 And Limitation Of Human Macrophage Apoptosis
  1347. Pre Clinical Mtor-Inhibition Of Acute Lymphoblastic Leukemia Cells Synergizes With Pro-Apoptotic Target Therapy Through Mcl-1 Down-Regulation
  1348. Pre-Apoptotic Response To Therapeutic Dna Damage Involves Protein Modulation Of Mcl-1, Hdm2 And Flt3 In Acute Myeloid Leukemia Cells
  1349. Pre-Clinical Assessment Of Mcl-1 As A Therapeutic Target In T-Cell Lymphomas
  1350. Preclinical Efficacy Of Sepantronium Bromide (Ym155) In Multiple Myeloma Is Conferred By Down Regulation Of Mcl-1
  1351. Preclinical Evaluation Of Amg 176, A Novel, Potent And Selective Mcl-1 Inhibitor With Robust Anti-Tumor Activity In Mcl-1 Dependent Cancer Models
  1352. Pre-Clinical Evaluation Of Mcl-1 Inhibition Through Maritoclax In Acute Myeloid Leukemia
  1353. Preclinical Evaluation Of The Simultaneous Inhibition Of Mcl-1 And Bcl-2 With The Combination Of S63845 And Venetoclax In Multiple Myeloma.
  1354. Preclinical Studies Of Apogossypolone, A Novel Pan Inhibitor Of Bcl-2 And Mcl-1, Synergistically Potentiates Cytotoxic Effect Of Gemcitabine In Pancreatic Cancer …
  1355. Preclinical Studies Of Apogossypolone: A New Nonpeptidic Pan Small-Molecule Inhibitor Of Bcl-2, Bcl-Xl And Mcl-1 Proteins In Follicular Small Cleaved Cell …
  1356. Predicting Cellular Response To Small Molecule Mcl-1 Antagonists
  1357. Predicting Response To Mcl-1 Targeting Agents In Nsclc And Multiple Myeloma
  1358. Preferential Targeting Of Mcl-1 By A Hydrocarbon-Stapled Bim Bh3 Peptide
  1359. Preparation Of Prokaryotic Expression Construct Of Bufo Japonicus Formosus Mcl-1 And Its Recombinant Protein Expression
  1360. Prevention Of Cytokine Withdrawal-Induced Apoptosis By Mcl-1 Requires Interaction Between Mcl-1 And Bim
  1361. Prevents Mcl-1 Protein Dephosphorylation At The Thr-163/Ser-159 Phosphodegron, Dramatically Reducing Expression In Mcl-1-Amplified Lymphoma Cells
  1362. Proapoptotic Bak Is Sequestered By Mcl-1 And Bcl-Xl, But Not Bcl-2, Until Displaced By Bh3-Only Proteins
  1363. Pro-Apoptotic Meiogynin A Derivatives That Target Bcl-Xl And Mcl-1
  1364. Probing The Difference Between Bh3 Groove Of Mcl-1 And Bcl-2 Protein: Implications For Dual Inhibitors Design
  1365. Prognostic Role Of Myeloid Cell Leukemia‐1 Protein (Mcl‐1) Expression In Human Gastric Cancer
  1366. Prognostic Significance Of A Short Sequence Insertion In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia
  1367. Progress In Research Of Structure, Function And Inhibitors Of Mcl-1 Protein
  1368. Progress Of Study On Relationship Between Mcl-1 Gene And Hematologic Malignancies-Review
  1369. Progress On Mcl-1 Small Molecule Inhibitors
  1370. Progression Of Rsearch For On Mcl-1 Mlecule [J]
  1371. Proinflammatory Lipids In Stored Blood And From Injury Delay Neutrophil Apoptosis Via Mcl-1 Expression.: 72
  1372. Prolactin Regulation Of Bcl-2 Family Members: Increased Expression Of Bcl-Xl But Not Mcl-1 Or Bad In Nb2-T Cells
  1373. Prolyl Hydroxylase 3 Attenuates Mcl-1–Mediated Atp Production To Suppress The Metastatic Potential Of Colorectal Cancer Cells
  1374. Promiscuous And Selective: How Intrinsically Disordered Bh3 Proteins Interact With Their Pro-Survival Partner Mcl-1
  1375. Promoter Knock-In Mutations Reveal A Role Of Mcl-1 In Thymocyte-Positive Selection And Tissue Or Cell Lineage-Specific Regulation Of Mcl-1 Expression
  1376. Promoting Vaginal Distribution Of E7 And Mcl-1 Sirna-Silencing Nanoparticles For Cervical Cancer Treatment
  1377. Prospects For Drug Designing: Similar Conserved Interactions Of Bim With Mcl-1 And Bcl-2
  1378. Proteasomal Degradation Of Mcl-1 By Maritoclax Induces Apoptosis And Enhances The Efficacy Of Abt-737 In Melanoma Cells
  1379. Proteasome Inhibitors Induce Apoptosis In Human Lung Cancer Cells Through A Positive Feedback Mechanism And The Subsequent Mcl-1 Protein Cleavage
  1380. Protection From Cell Death By Mcl-1 Is Mediated By Membrane Hyperpolarization Induced By K+ Channel Activation
  1381. Protection Of Cll B Cells By A Follicular Dendritic Cell Line Is Dependent On Induction Of Mcl-1
  1382. Protective Effect Of Melatonin On Oxaliplatin‐Induced Apoptosis Through Sustained Mcl‐1 Expression And Anti‐Oxidant Action In Renal Carcinoma Caki Cells
  1383. Protein Kinase C-Eta Regulates Mcl-1 Level Via Erk1
  1384. Protein Kinase Ck2 Enhances Mcl‐1 Gene Expression Through The Serum Response Factor‐Mediated Pathway In The Rat Hippocampus
  1385. Protein Kinase G Type‐Iα (Pkg‐Iα) Signaling Pathway Promotes Creb Phosphorylation And Maintains Higher C‐Iap1, Livin, Survivin, And Mcl‐1 Expression And The …
  1386. Protein Phosphatase 1 Activation And Alternative Splicing Of Bcl‐X And Mcl‐1 By Egcg+ Ibuprofen
  1387. Proteolysis Targeting Chimeras For The Selective Degradation Of Mcl-1/Bcl-2 Derived From Nonselective Target Binding Ligands
  1388. Ps06. 02 Drug-Tolerant Egfr Mutant Lung Cancer Cells Rely On Mcl-1 Translation And Are Eliminated By Mcl-1 Inhibitors: Topic: Pulmonology
  1389. Pseudomonas Exotoxin A-Mediated Apoptosis Is Bak Dependent And Preceded By The Degradation Of Mcl-1
  1390. Puma* Mcl-1 Interaction Is Not Sufficient To Prevent Rapid Degradation Of Mcl-1
  1391. Purified Mouse Anti-Human Mcl-1
  1392. Purported Mcl-1 Inhibitor Marinopyrrole A Fails To Show Selective Cytotoxicity For Mcl-1-Dependent Cell Lines
  1393. Pyoluteorin Derivatives Induce Mcl-1 Degradation And Apoptosis In Hematological Cancer Cells
  1394. Pyridoclax And Its Derivatives From Oligopyridine Family Directly Inhibit Mcl-1 And Exert Potent Antitumor Effects On Ovarian Cancer In Vitro And In Vivo
  1395. Quercetin Downregulates Mcl-1 By Acting On Mrna Stability And Protein Degradation
  1396. Quercetin Induces Tumor-Selective Apoptosis Involving Downregulation Of Mcl-1 And Activation Of Bax
  1397. Quercetin Induces Tumor-Selective Apoptosis Through Downregulation Of Mcl-1 And Activation Of Bax
  1398. Quercetin-Mediated Mcl-1 And Survivin Downregulation Restores Trail-Induced Apoptosis In Non-Hodgkin Lymphoma B-Cells
  1399. Quercetin-Mediated Mcl-1 And Survivin Downregulation Restores Trail-Induced Apoptosis In Non-Hodgkin’S Lymphoma B Cells
  1400. Quinacrine Sensitizes Hepatocellular Carcinoma Cells To Trail Via Up-Regulating Dr5 And Eradicating Mcl-1
  1401. Rankl Increases The Level Of Mcl-1 In Osteoclasts And Reduces Bisphosphonate-Induced Osteoclast Apoptosis In Vitro
  1402. Rapid Optimization Of Mcl-1 Inhibitors Using Stapled Peptide Libraries Including Non-Natural Side Chains
  1403. Rapid Turnover Of Mcl-1 Couples Translation To Cell Survival And Apoptosis
  1404. Rassf6-Mediated Inhibition Of Mcl-1 Through Jnk Activation Improves The Anti-Tumor Effects Of Sorafenib In Renal Cell Carcinoma
  1405. Rational Design Of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors
  1406. Rational For A Combination Of Bortezomib And Doxorubicin In The Treatment Of Multiple Myeloma: A Pivotal Role For Mcl-1.
  1407. Rationally Derived Drug Combinations With The Novel Mcl-1 Inhibitor Eu-5346 In Breast Cancer
  1408. Rb, Mcl-1 And P53 Expression Correlate With Clinical Outcome In Patients With Liver Metastases From Colorectal Cancer
  1409. Re: Prognostic Significance Of A Short Sequence Insertion In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia
  1410. Reactive Oxygen Species Mediate Cancer Stem-Like Cells And Determine Bortezomib Sensitivity Via Mcl-1 And Zeb-1 In Mantle Cell Lymphoma
  1411. Recent Advances In Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein
  1412. Recent Advances In The Development Of Mcl-1 Inhibitors For Cancer Therapy
  1413. Reciprocal Protection Of Mcl-1 And Bim From Ubiquitin-Proteasome Degradation
  1414. Recombinant Mda-7/Il24 Suppresses Prostate Cancer Bone Metastasis Through Downregulation Of The Akt/Mcl-1 Pathway
  1415. Reduced Association Of Anti-Apoptotic Protein Mcl-1 With E3 Ligase Mule Increases The Stability Of Mcl-1 In Breast Cancer Cells
  1416. Reduced Mast Cell And Basophil Numbers And Function In Cpa3-Cre; Mcl-1Fl/Fl Mice
  1417. Reducing Mcl-1 By Homoharringtonine Induces Apoptosis In Chronic Lymphocytic Leukemia Cells
  1418. Reducing Mcl-1 Gene Dosage Induces Dopaminergic Neuronal Loss And Motor Impairments In Park2 Knockout Mice
  1419. Reduction Of Trail-Induced Mcl-1 And Ciap2 By C-Myc Or Sorafenib Sensitizes Resistant Human Cancer Cells To Trail-Induced Death
  1420. Regulated Expression Of Anti-Apoptotic Mcl-1 And A1 Controls The Population Structure Of Myeloid Derived Suppressor Cells (P1070)
  1421. Regulation Of 2-Methoxyestradiol-Induced Cell Apoptosis By Mcl-1 And Bax Genes In Myelodysplastic Syndrome
  1422. Regulation Of A1 And Mcl-1 From Costimulatory Signals Affects T Cell Survival (47.2)
  1423. Regulation Of Anti-Apoptotic Bcl-2 Family Protein Mcl-1 By S6 Kinase 2
  1424. Regulation Of Antiapoptotic Mcl-1 Function By Gossypol: Mechanistic Insights From In Vitro Reconstituted Systems
  1425. Regulation Of Heat-Induced Apoptosis By Mcl-1 Degradation And Its Inhibition By Hsp70
  1426. Regulation Of Intestinal Epithelial Apoptosis By Protease-Activated Receptor 2 Involves Egfr-Transactivation And Is Associated With Mcl-1 Upregualtion (151.1)
  1427. Regulation Of Macrophage Cell Death Proteins Mcl-1 And Bax During Infection By Mycobacterium Tuberculosis
  1428. Regulation Of Mcl-1 Alternative Splicing By Hnrnp F, H1 And K In Breast Cancer Cells
  1429. Regulation Of Mcl-1 And Caspase Family Members In Pmn By Laminin And Oxidative Stress.: 222
  1430. Regulation Of Mcl-1 By Constitutive Activation Of Nf-Kappab Contributes To Cell Viability In Human Esophageal Squamous Cell Carcinoma Cells
  1431. Regulation Of Mcl-1 By E2F-1 In Endoplasmic Reticulum Stress In Gastric Adenocarcinoma Cells [J]
  1432. Regulation Of Mcl-1 By Srsf1 And Srsf5 In Cancer Cells
  1433. Regulation Of Mcl-1 Expression In Context To Bone Marrow Stromal Microenvironment In Chronic Lymphocytic Leukemia
  1434. Regulation Of Mcl‐1 Expression In Rheumatoid Arthritis Synovial Macrophages
  1435. Regulation Of Neutrophil Apoptosis By Mcl-1
  1436. Regulation Of Neutrophil Survival/Apoptosis By Mcl-1
  1437. Regulation Of Placental Autophagy By The Bcl-2 Family Proteins Myeloid Cell Leukemia Factor 1 (Mcl-1) And Matador/Bcl-2 Related Ovarian Killer (Mtd/Bok)
  1438. Regulation Of The Bcl-2 Family Members Bim, Puma And Mcl-1 By Mek/Erk Signaling Plays A Critical Role In Survival Of Melanoma Cells
  1439. Relationship Of Mcl-1 Isoforms, Ratio P21Waf1/Cyclin A, And Jun Kinase Phosphorylation To Apoptosis In Human Breast Carcinomas
  1440. Renieramycin T Induces Lung Cancer Cell Apoptosis By Targeting Mcl-1 Degradation: A New Insight In The Mechanism Of Action
  1441. Reply To Hu Et Al.: Mcl-1 Reduction Due To Caspase-Dependent Cleavage During Endoplasmic Reticulum Stress-Induced Apoptosis
  1442. Repression Of Mcl-1 And Disruption Of The Mcl-1/Bak Interaction In Myeloma Cells Couple Er Stress To Mitochondrial Apoptosis
  1443. Repression Of Mcl-1 Expression By The Cdc7/Cdk9 Inhibitor Pha-767491 Overcomes Bone Marrow Stroma-Mediated Drug Resistance In Aml
  1444. Repurposing Of Mtor Complex Inhibitors Attenuates Mcl-1 And Sensitizes To Parp Inhibition
  1445. Requirement For Antiapoptotic Mcl-1 In The Survival Of Bcr-Abl B-Lineage Acute Lymphoblastic Leukemia
  1446. Resistance To The Novel Translation Inhibitor Silvestrol Is Mediated By Elevated Mcl-1 Expression.
  1447. Response To Yang-Yen: Does N-Terminal Processing Of Mcl-1 Occur At Mitochondrial Outer Membrane Or Matrix?
  1448. Response: Re: Prognostic Significance Of A Short Sequence Insertion In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia
  1449. Resveratrol And Clofarabine Induces A Preferential Apoptosis-Activating Effect On Malignant Mesothelioma Cells By Mcl-1 Down-Regulation And Caspase-3 …
  1450. Resveratrol Suppresses Cell Proliferation Via Inhibition Of Stat3 Phosphorylation And Mcl-1 And Ciap-2 Expression In Htlv-1-Infected T Cells
  1451. Revealing A Non-Canonical Role Of Anti-Apoptotic Mcl-1 In Early Embryonic Development
  1452. Rna Antagonist Compounds For The Modulation Of Mcl-1
  1453. Rna Silencing Of Mcl-1 Enhances Abt-737-Mediated Apoptosis In Melanoma: Role For A Caspase-8-Dependent Pathway
  1454. Rnai-Mediated Inhibition Of Mcl-1 Expression Enhances Apoptosis In Imatinib-Treated Cml Progenitors
  1455. Role Of Bile Salt In Regulating Mcl-1 Phosphorylation And Chemoresistance In Hepatocellular Carcinoma Cells
  1456. Role Of Ku70 In Deubiquitination Of Mcl-1 And Suppression Of Apoptosis
  1457. Role Of Mcl-1 In Regulation Of Cell Death In Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes In Vitro
  1458. Role Of Mitogen‐Activated Protein Kinases And Mcl‐1 In Apoptosis Induction By Withaferin A In Human Breast Cancer Cells
  1459. Role Of Myeloid Cell Factor-1 (Mcl-1) In Chronic Lymphocytic Leukemia
  1460. Role Of Myeloid Cell Leukemia 1 (Mcl-1) In Mediating Chemoresistance Towards Bcl-2 Homology 3 (Bh3) Mimetics In Lymphoid Malignancies
  1461. Role Of Non-Native Electrostatic Interactions In The Coupled Folding And Binding Of Puma With Mcl-1
  1462. Role Of Raf/Mek/Erk Pathway, P‐Stat‐3 And Mcl‐1 In Sorafenib Activity In Human Pancreatic Cancer Cell Lines
  1463. Roles Of Microrna-29A In Expression Of Bcl-2 And Mcl-1 In Rat Cardiomyocytes
  1464. Roscovitine-Induced Apoptosis In Neutrophils And Neutrophil Progenitors Is Regulated By The Bcl-2-Family Members Bim, Puma, Noxa And Mcl-1
  1465. Running Title: Mcl-1 And Mitochondrial Ca2
  1466. S1, A Bid-Like Bh3 Mimetic, Induces Apoptosis By Dynamic Change Of Mcl-1 And Dependent On Bak, Not Bax
  1467. S1, A Novel Pan-Bh3 Mimetic, Induces Apoptosis In Mcl-1-Overexpressing Cells Through Bak
  1468. S63845, A Novel Bh3 Mimetic Mcl-1 Inhibitor Synergizes With Midostaurin To Induce Potent Apoptosis In Acute Myeloid Leukemia Cells Carrying Flt3-Itd Mutations
  1469. S63845, An Mcl-1 Selective Bh3 Mimetic: Another Arrow In Our Quiver
  1470. S6K1 Inhibition Enhances Tamoxifen-Induced Cell Death In Mcf-7 Cells Through Translational Inhibition Of Mcl-1 And Survivin
  1471. Sabutoclax (Bi97C1) And Bi112D1, Putative Inhibitors Of Mcl-1, Induce Mitochondrial Fragmentation Either Upstream Of Or Independent Of Apoptosis
  1472. Sabutoclax, A Mcl-1 Antagonist, Inhibits Tumorigenesis In Transgenic Mouse And Human Xenograft Models Of Prostate Cancer
  1473. Saga Of Mcl-1: Regulation From Transcription To Degradation
  1474. Sann-Joong-Kuey-Jian-Tang Decreases The Protein Expression Of Mcl‑1 And Tctp And Increases That Of Tnf-Α And Bax In Bxpc‑3 Pancreatic Carcinoma Cells
  1475. Sar By Interligand Nuclear Overhauser Effects (Iloes) Based Discovery Of Acylsulfonamide Compounds Active Against Bcl-Xl And Mcl-1
  1476. Sec6/8 Regulates Bcl-2 And Mcl-1, But Not Bcl-Xl, In Malignant Peripheral Nerve Sheath Tumor Cells
  1477. Securidaca–Saponins Are Natural Inhibitors Of Akt, Mcl-1, And Bcl2L1 In Cervical Cancer Cells
  1478. Securidaca–Saponins Are Natural Inhibitors Of Akt, Mcl-1, And Bcl2L1 In Cervical Cancer Cells [Corrigendum]
  1479. ‘Seed’Analysis Of Off-Target Sirnas Reveals An Essential Role Of Mcl-1 In Resistance To The Small-Molecule Bcl-2/Bcl-X L Inhibitor Abt-737
  1480. Seeking A Mcl-1 Inhibitor
  1481. Selection Of Antibodies For Immunohistochemical Detection Of Bcl-2 Family Members In Dogs And Immunohistochemical Expression Pattern Of Mcl-1 And Bcl-X In Canine …
  1482. Selective Bh3-Mimetics Targeting Bcl-2, Bcl-Xl Or Mcl-1 Induce Severe Mitochondrial Perturbations
  1483. Selective Cdk9 Inhibition Overcomes Trail Resistance By Concomitant Suppression Of Cflip And Mcl-1
  1484. Selective Flt3 Inhibitor Fi-700 Neutralizes Mcl-1 And Enhances P53-Mediated Apoptosis In Aml Cells With Activating Mutations Of Flt3 Through Mcl-1/Noxa …
  1485. Selective Induction Of Cell Death In Melanoma Cell Lines Through Targeting Of Mcl-1 And A1
  1486. Selective Inhibitors Of Mcl-1 With Potent Activity Against Multiple Myeloma Patient Cells And Animal Xenografts.
  1487. Selective Mcl-1 Inhibition By Azd5991 Induces On-Target Cell Death And Achieves Antitumor Activity In Multiple Myeloma And Acute Myeloid Leukemia
  1488. Selective Roles For Antiapoptotic Mcl-1 During Granulocyte Development And Macrophage Effector Function
  1489. Selective Small Molecule Inhibition Of Anti-Apoptotic Mcl-1
  1490. Selective Small Molecule Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors: Novel Agents In Cancer Therapy
  1491. Selective Small Molecule Targeting Of Anti-Apoptotic Mcl-1
  1492. Selectively Targeting Mcl-1 For The Treatment Of Acute Myelogenous Leukemia And Solid Tumors
  1493. Seliciclib (Cyc202 Or R-Roscovitine), A Small-Molecule Cyclin-Dependent Kinase Inhibitor, Mediates Activity Via Down-Regulation Of Mcl-1 In Multiple Myeloma
  1494. Sensitization Of Colon Cancer (Cc) Cells To The Cytotoxic Ligand Trail By The Cox-2 Inhibitor Dup-697 Correlates With Downregulation Of Mcl-1 And Clustering Of Dr5
  1495. Sensitization Of Ovarian Carcinoma Cells To Bcl-Xl-Targeting Strategies Through Indirect Modulation Of Mcl-1 Activity By Mr22388, A Molecule Of The Tripentone …
  1496. Serine 162, An Essential Residue For The Mitochondrial Localization, Stability And Anti-Apoptotic Function Of Mcl-1
  1497. Serine 64 Phosphorylation Enhances The Antiapoptotic Function Of Mcl-1
  1498. Serine Phosphorylation Of Stat3 Is Essential For Mcl-1 Expression And Macrophage Survival
  1499. Sf3B1 Inhibitors Sensitize Head And Neck Squamous Cell Carcinoma To Bcl-Xl Inhibition By Regulating Mcl-1 Alternative Splicing.
  1500. Shiga Toxin Induces Decreased Expression Of The Anti-Apoptotic Protein Mcl-1 Concomitant With The Onset Of Endothelial Apoptosis
  1501. Short Nucleotide Insertions In The Mcl-1 Promoter Affect Its Gene Expression.
  1502. Short Nucleotide Polymorphic Insertions In The Mcl-1 Promoter Affect Gene Expression
  1503. Side-By-Side Comparison Of Bh3-Mimetics Identifies Mcl-1 As A Key Therapeutic Target In Aml
  1504. Significance Of Mcl-1 Expressions In Gastric Cancer By Tissue Microarray
  1505. Silence Of Mcl-1 Upstream Signaling By Shrna Abrogates Multiple Myeloma Growth
  1506. Silencing Of Mcl-1 By Mir-101 Induces Apoptosis And Enhances Etoposide Chemosensitivity In A549 Lung Cancer Cells
  1507. Simultaneous Chk1 And Mek1/2 Inhibition Circumvents Mcl-1 Anti-Apoptotic Function And Bortezomib Resistance In Human Multiple Myeloma Cells
  1508. Simultaneous Chk1 And Mek1/2 Inhibition Circumvents Mcl-1-Mediated Anti-Apoptotic Functions And Bortezomib Resistance In Human Multiple Myeloma Cells.
  1509. Simultaneous Inhibition Of Dna Methyltransferase And Histone Deacetylase Induces P53-Independent Apoptosis Via Down-Regulation Of Mcl-1 In Acute Myelogenous …
  1510. Simultaneous Inhibition Of Mcl-1 And Induction Of Dna Damage Accumulation By Chidamide, A Novel Selective Hdaci, Potentiates The Cytotoxicity Of Abt-199 In …
  1511. Simultaneous Inhibition Of Mcl-1 And Xiap To Induce Apoptosis In Aml Cells.
  1512. Simultaneous Knock-Down Of Bcl-Xl And Mcl-1 Induces Apoptosis In Gemcitabine-Sensitive And-Resistant Pancreatic Cancer Cells
  1513. Simultaneous Knock-Down Of Bcl-Xl And Mcl-1 Induces Apoptosis Through Bax Activation In Pancreatic Cancer Cells
  1514. Simultaneous Suppression Of Mcl-1 And Survivin Expression Via Rna Interference In Hl-60 Leukemia Cell Line
  1515. Simultaneous Targeting Of Atm And Mcl-1 Increases Cisplatin Sensitivity Of Cisplatin-Resistant Non-Small Cell Lung Cancer
  1516. Simvastatin Enhances Irinotecan-Induced Apoptosis In Prostate Cancer Via Inhibition Of Mcl-1
  1517. Sindbis Viral Vector Induced Apoptosis Requires Translational Inhibition And Signaling Through Mcl-1 And Bak
  1518. Sirt6 Is Upregulated And Associated With Cancer Aggressiveness In Papillary Thyroid Cancer Via Braf/Erk/Mcl‑1 Pathway
  1519. Small Interfering Rna Targeting Mcl-1 Enhances Proteasome Inhibitor-Induced Apoptosis In Various Solid Malignant Tumors
  1520. Small Molecule Inhibitors Of Membrane-Bound Mcl-1 And Bcl-2.
  1521. Small Molecule Mcl-1 Inhibitors For The Treatment Of Cancer
  1522. Small Molecule Mcl-1 Inhibitors Induce Apoptosis And Death In Multiple Cancer Subtypes In Vitro
  1523. Small Molecule Obatoclax (Gx15-070) Antagonizes Mcl-1 And Overcomes Mcl-1-Mediated Resistance To Apoptosis
  1524. Small Molecules Targeting Mcl-1: The Search For A Silver Bullet In Cancer Therapy
  1525. Small‐Molecule And Peptide Inhibitors Of The Pro‐Survival Protein Mcl‐1
  1526. Small-Molecule Inhibitors Of The Mcl-1 Oncoprotein
  1527. Small-Molecule Mcl-1 Inhibitors: Emerging Anti-Tumor Agents
  1528. Sns-032, A Novel Inhibitor Of Cyclin-Dependent Kinases 2, 7 And 9, Blocks Transcription Of Cyclin D1 And Mcl-1, Causing Cell Death In Mantle Cell Lymphoma Cell …
  1529. Sodium Salicylate Promotes Neutrophil Apoptosis By Stimulating Caspase-Dependent Turnover Of Mcl-1
  1530. Solution Structure Of Mcl-1 And Its Complexes
  1531. Solution Structure Of Prosurvival Mcl-1 And Characterization Of Its Binding By Proapoptotic Bh3-Only Ligands
  1532. Sorafenib Induces Cell Death In Chronic Lymphocytic Leukemia By Translational Downregulation Of Mcl-1
  1533. Sorafenib Induces Endometrial Carcinoma Apoptosis By Inhibiting Elk‐1‐Dependent Mcl‐1 Transcription And Inducing Akt/Gsk3Β‐Dependent Protein Degradation
  1534. Sorafenib Inhibition Of Mcl-1 Accelerates Atra-Induced Apoptosis In Differentiation-Responsive Aml Cells
  1535. Sorafenib Inhibits In Vitro Osteoclastogenesis By Down-Modulating Mcl-1
  1536. Sorafenib Plus Aspirin Promotes Trail-Induced Apoptosis By Targeting Flip And Mcl-1 And Potentiates Growth Inhibition In Colon Cancer Cells
  1537. Sorafenib Sensitizes (−)-Gossypol-Induced Growth Suppression In Androgen-Independent Prostate Cancer Cells Via Mcl-1 Inhibition And Bak Activation
  1538. Sorafenib-Induced Apoptosis Of Chronic Lymphocytic Leukemia Cells Is Associated With Downregulation Of Raf And Myeloid Cell Leukemia Sequence 1 (Mcl-1)
  1539. Sorafenib-Mediated Mcl-1 And Cflipl Down-Regulation Synergistically Increase Trail Lethality In Human Leukemia Cells
  1540. Specific Cleavage Of Mcl-1 By Caspase-3 In Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (Trail)-Induced Apoptosis In Jurkat Leukemia T Cells
  1541. Sphingosine 1-Phosphate Induces Mcl-1 Upregulation And Protects Multiple Myeloma Cells Against Apoptosis
  1542. Sphingosine Kinase-1 Mediates Bcr/Abl-Induced Upregulation Of Mcl-1 In Chronic Myeloid Leukemia Cells
  1543. Sphingosine-1-Phosphate Receptor S1P 1 Via Reciprocal Erk-Dependent Suppression Of Bim And Pi-3-Kinase/Protein Kinase C-Mediated Upregulation Of Mcl-1
  1544. Spontaneous Oligomerization Of Bak/Bax Is Suppressed By Hetero-Dimerization With Mcl-1
  1545. Stabilization And Enhancement Of The Antiapoptotic Activity Of Mcl-1 By Tctp
  1546. Stapled Bh3 Peptides Against Mcl-1: Mechanism And Design Using Atomistic Simulations
  1547. Stat3 And Mcl-1 Associate To Cause A Mesenchymal Epithelial Transition
  1548. Stat3-And Gsk3Β-Mediated Mcl-1 Regulation Modulates Tpf Resistance In Oral Squamous Cell Carcinoma
  1549. Stat3-Mediated Transcription Of Bcl-2, Mcl-1 And C-Iap2 Prevents Apoptosis In Polyamine-Depleted Cells
  1550. Statins Enhance Killing Of Multiple Myeloma Cells By The Bcl-2 Inhibitor Venetoclax And The Mcl-1 Inhibitor S63845
  1551. Staurosporine Resistance In Inflammatory Neutrophils Is Associated With The Inhibition Of Caspase‐And Proteasome‐Mediated Mcl‐1 Degradation
  1552. Sti571 Induces Apoptosis Of K562 Cells Through Down-Regulation Of Anti-Apoptotic Protein Mcl-1 And Bcl-Xl Expression
  1553. Strain-Specific Suppression Of Microrna-320 By Carcinogenic Helicobacter Pylori Promotes Expression Of The Antiapoptotic Protein Mcl-1
  1554. Strong Correlation Between Vegf And Mcl-1 Mrna Expression Levels In B-Cell Chronic Lymphocytic Leukemia
  1555. Structural Insights Into The Degradation Of Mcl-1 Induced By Bh3 Domains
  1556. Structural Insights Into The Design Of Small Molecule Inhibitors That Selectively Antagonize Mcl-1
  1557. Structural Re‐Engineering Of The Α‐Helix Mimetic Jy‐1‐106 Into Small Molecules: Disruption Of The Mcl‐1–Bak‐Bh3 Protein–Protein Interaction With 2, 6‐Di …
  1558. Structure Based Design Of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
  1559. Structure Of A Myeloid Cell Leukemia-1 (Mcl-1) Inhibitor Bound To Drug Site 3 Of Human Serum Albumin
  1560. Structure Of The Bh3 Domains From The P53-Inducible Bh3-Only Proteins Noxa And Puma In Complex With Mcl-1
  1561. Structure-Based Design And Development Of Pyrazolopyridine-Based Inhibitors Of Mcl-1
  1562. Structure-Based Design And Synthesis Of Selective Small Molecule Inhibitors For Mcl-1, An Important Cancer Target
  1563. Structure-Based Design Of 3-Carboxy-Substituted 1, 2, 3, 4-Tetrahydroquinolines As Inhibitors Of Myeloid Cell Leukemia-1 (Mcl-1)
  1564. Structure-Based Design Of Inhibitors Of The Mcl-1 Oncoprotein
  1565. Structure-Based Design Of N-Substituted 1-Hydroxy-4-Sulfamoyl-2-Naphthoates As Selective Inhibitors Of The Mcl-1 Oncoprotein
  1566. Structure-Based Design, Synthesis And Evaluation Of Novel And Selective Small-Molecule Inhibitors Of The Anti-Apoptotic Protein Mcl-1.
  1567. Structure-Function Analysis Of The Mcl-1 Protein Identifies A Novel Senescence-Regulating Domain
  1568. Structure-Guided De Novo Design Of Selective Mcl-1 Inhibitors: Synthesis, Structural And Biochemical Characterization
  1569. Structure-Guided Design Of A Series Of Mcl-1 Inhibitors With High Affinity And Selectivity
  1570. Structure-Guided Design Of Pyridoclax Derivatives Based On Noxa/Mcl-1 Interaction Mode
  1571. Structure-Guided Discovery Of A Selective Mcl-1 Inhibitor With Cellular Activity
  1572. Structure-Guided Discovery Of Selective Mcl-1 Inhibitors
  1573. Studies Of (E)-T-Butyl-2-((E)-2-Methyl-3-Phenylallylidene) Hydrazine Carboxylate And (E)-T-Butyl-2-((E)-3-Phenylallylidene) Hydrazine Carboxylates As A Possible Mcl-1 …
  1574. Studies Of The Role Of Mcl-1 In Haemopoiesis And Leukaemia
  1575. Studies Of Tw-37, A New Nonpeptidic Small-Molecule Inhibitor Of Bcl-2, In Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action On Both Bcl-2 And Mcl-1
  1576. Studies On The Role Of Bid And Mcl-1 In The Regulation Of Apoptosis.
  1577. Study On Apoptosis Of Peripheral Neutrophil And Mcl-1, Caspase-3 Expression In Preeclamptic Patients
  1578. Substituted Indole Mcl-1 Inhibitors: A Patent Evaluation (Wo2015148854A1)
  1579. Sumoylation Site In Mcl-1 Regulates Its Anti-Apoptotic Activity
  1580. Supplemental Data The Bh3 Mimetic Abt-737 Targets Selective Bcl-2 Proteins And Efficiently Induces Apoptosis Via Bak/Bax If Mcl-1 Is Neutralized
  1581. Supplementary Figure 1| Knockdown Of Mcl-1 Sensitizes H196 Cells To Abt-737.
  1582. Supplementary Materials: Role Of Non-Native Electrostatic Interactions In The Coupled Folding And Binding Of Puma With Mcl-1
  1583. Suppression Of Mcl‐1 Induces Apoptosis In Mouse Peritoneal Macrophages Infected With Mycobacterium Tuberculosis
  1584. Suppression Of Mcl-1 Via Rna Interference Sensitizes Human Hepatocellular Carcinoma Cells Towards Apoptosis Induction
  1585. Suppression Of Myeloid Cell Leukemia-1 (Mcl-1) Enhances Chemotherapy-Associated Apoptosis In Gastric Cancer Cells
  1586. Suppression Of Pmn Apoptosis By Hypoxia Is Dependent On Mcl-1 And Mapk Activity
  1587. Surface Plasmon Resonance Study Of Apoptotic Regulators Bcl-2, Bcl-W, Bcl-Xl, And Mcl-1 Indicate That The Preclinical Small Molecule Inhibitor (Smi) Tw-37 Binds To …
  1588. Surface Plasmon Resonance Study Of Apoptotic Regulators Bcl-2, Bcl-W, Bcl-Xl, Mcl-1 And A1 And The Small Molecule Inhibitor (Smi) Tw-37: The Idea Of A Temporal …
  1589. Survival Control Of Malignant Lymphocytes By Anti-Apoptotic Mcl-1
  1590. Survival Factor Withdrawal-Induced Apoptosis Of Tf-1 Cells Involves A Trb2-Mcl-1 Axis-Dependent Pathway
  1591. Survival Of Mycobacterium Tuberculosis In Host Macrophages Involves Resistance To Apoptosis Dependent Upon Induction Of Antiapoptotic Bcl-2 Family Member Mcl-1
  1592. Survivin Inhibitor Ym-155 Sensitizes Trail-Resistant Glioma Cells To Apoptosis Through Mcl-1 Down-Regulation And By Engaging The Mitochondrial Death Pathway
  1593. Sustained A1 And Mcl-1 Expression From Costimulatory Signals Promotes T Cell Survival (50.20)
  1594. Sustained Signaling Through The B-Cell Receptor Induces Mcl-1 And Promotes Survival Of Chronic Lymphocytic Leukemia B Cells
  1595. Sustained Signaling Through The B-Cell Receptor Induces Mcl-1 And Promotes Survival Of Chronic Lymphocytic Leukemia B-Cells.
  1596. Syk Inhibition Disrupts The Cross-Talk Between B-Cell Activation Factor (Baff) And B-Cell Receptor (Bcr) And Thereby Antagonizes Mcl-1 In Chronic Lymphocytic …
  1597. Syk Inhibition Thwarts The Baff-B-Cell Receptor Crosstalk And Thereby Antagonizes Mcl-1 In Chronic Lymphocytic Leukemia
  1598. Synergism Between P53 And Mcl-1 In Protecting From Hepatic Injury, Fibrosis And Cancer
  1599. Synergistic Action Of The Mcl-1 Inhibitor S63845 With Current Therapies In Preclinical Models Of Triple-Negative And Her2-Amplified Breast Cancer
  1600. Synergistic Activity Of The Mcl-1 Inhibitor S63845 With Midostaurin In Preclinical Human Models Of Flt3-Itd Mutated Acute Myeloid Leukemia (Aml)
  1601. Synergistic Activity Of The Mcl-1-Specific Inhibitor S63845 With Venetoclax In B-Cell Precursor Acute Lymphoblastic Leukemia
  1602. Synergistic Anti-Proliferative Effects Of Combination Of Abt-263 And Mcl-1 Selective Inhibitor A-1210477 On Cervical Cancer Cell Lines
  1603. Synergistic Antitumor Activity Of Gemcitabine And Abt-737 In Vitro And In Vivo Through Disrupting The Interaction Of Usp9X And Mcl-1
  1604. Synergistic Anti-Tumor Activity Of Mcl-1 Antisense Oligonucleotides And Docetaxel In Gastric Cancer Cells
  1605. Synergistic Induction Of Apoptotic Cell Death In Aml By Targeting Bcl-2 With Abt-199 In Combination With Bcl-Xl/Mcl-1 Inhibition Or Selective Kinase Inhibitors
  1606. Synergistic Interactions Between Vorinostat And Sorafenib In Chronic Myelogenous Leukemia Cells Involve Mcl-1 And P21Cip1 Down-Regulation
  1607. Synthesis And Evaluation Of Substituted Hexahydronaphthalenes As Novel Inhibitors Of The Mcl-1/Bimbh3 Interaction
  1608. Synthesis Of A Rhodanine-Based Compound Library Targeting Bcl-Xl And Mcl-1
  1609. Synthesis Of Cell-Permeable Stapled Bh3 Peptide-Based Mcl-1 Inhibitors Containing Simple Aryl And Vinylaryl Cross-Linkers
  1610. Tailored Fragments Of Roseophilin Selectively Antagonize Mcl-1 In Vitro
  1611. Tankyrase 1 Interacts With Mcl-1 Proteins And Inhibits Their Regulation Of Apoptosis
  1612. Tanshinone Iia Inhibits Human Gastric Carcinoma Ags Cell Growth By Decreasing Bip, Tctp, Mcl‑1 And Bcl‑Xl And Increasing Bax And Chop Protein …
  1613. Tanshinone Iia Inhibits The Growth Of Pancreatic Cancer Bxpc‑3 Cells By Decreasing Protein Expression Of Tctp, Mcl‑1 And Bcl‑Xl
  1614. Targeted Delivery Of Ubiquitin-Conjugated Bh3 Peptide-Based Mcl-1 Inhibitors Into Cancer Cells
  1615. Targeted Mcl-1 Inhibition To Induce Cell Death And Synergize With Conventional Chemotherapeutic Agents In Diffuse Large B-Cell Lymphoma (Dlbcl) Pre-Clinical …
  1616. Targeted Therapy: Sunitinib Modulates Mcl-1 And Mtor Signalling
  1617. Targeting Acute Myeloid Leukemia By Dual Inhibition Of Pi3K Signaling And Cdk9-Mediated Mcl-1 Transcription
  1618. Targeting Aml Through Apoptosis Activation Using Bcl-2/Mcl-1 Or Bcl-2/Hdm2 Inhibitor Combination Therapies
  1619. Targeting Cdk9 And Mcl-1 By A New Cdk9/P-Tefb Inhibitor With And Without 5-Fluorouracil In Esophageal Adenocarcinoma
  1620. Targeting Destruction Of Mcl-1 By Activation Of Protein Phosphatase 2A In Cll And B-Cell Lymphomas
  1621. Targeting Flip And Mcl‐1 Using A Combination Of Aspirin And Sorafenib Sensitizes Colon Cancer Cells To Trail
  1622. Targeting Kpnb1 Overcomes Trail Resistance By Regulating Dr5, Mcl-1 And Flip In Glioblastoma Cells
  1623. Targeting K-Ras, Pak-1, And Mcl-1 For The Treatment Of Cancer
  1624. Targeting Mcl-1 And Bak As A Therapeutic Tool To Selectively Induce Apoptosis In Hepaptocellualr Carcinoma
  1625. Targeting Mcl-1 And Other Bcl-2 Family Member Proteins In Cancer Therapy
  1626. Targeting Mcl-1 By Proteasome Inhibitors Enhances The Anti-Tumor Activity Of Venetoclax In Mantle Cell Lymphoma Pre-Clinical Models
  1627. Targeting Mcl-1 Enhances Dna Replication Stress Sensitivity To Cancer Therapy
  1628. Targeting Mcl-1 Expression, Through The Inhibition Of Cdk9 And Super Enhancer Driven Transcription, Offers Multiple Opportunities For Rational Drug Combinations
  1629. Targeting Mcl-1 For Multiple Myeloma (Mm) Therapy: Drug-Induced Generation Of Mcl-1 Fragment Mcl-1128–350 Triggers Mm Cell Death Via C- Jun Upregulation
  1630. Targeting Mcl-1 For Multiple Myeloma (Mm) Therapy: Drug-Induced Generation Of Mcl-1 Fragment Mcl-1128–350 Triggers Mm Cell Death Via C-Jun Upregulation
  1631. Targeting Mcl-1 For Radiosensitization Of Pancreatic Cancers
  1632. Targeting Mcl-1 For The Therapy Of Cancer
  1633. Targeting Mcl-1 Inhibits Survival And Self-Renewal Of Hepatocellular Cancer Stem-Like Cells
  1634. Targeting Mcl-1 Regulated Apoptosis Pathway As A Novel Therapy In Pancreatic Cancer
  1635. Targeting Mcl-1 Sensitizes Flt3-Itd-Positive Leukemias To Cytotoxic Therapies
  1636. Targeting Mcl-1 Sensitizes Human Esophageal Squamous Cell Carcinoma Cells To Cisplatin-Induced Apoptosis
  1637. Targeting Mcl-1/Bcl-Xl Forestalls The Acquisition Of Resistance To Abt-199 In Acute Myeloid Leukemia
  1638. Targeting Of Mcl-1 Kills Myc-Driven Mouse And Human Lymphomas Even When They Bear Mutations In P53
  1639. Targeting Sf3B1 Mediated Splicing Control Of Mcl-1 In Chronic Lymphocytic Leukemia
  1640. Targeting The Anti-Apoptotic Protein Mcl-1 In Human Cancer
  1641. Targeting The Apoptotic Mcl-1-Puma Interface With A Dual-Acting Compound
  1642. Targeting The Bcl-2/Bh3 Protein-Protein Interaction: Identification, Design, And Synthesis Of New Selective Inhibitors Of The Mcl-1/Bh3 Interaction
  1643. Targeting The Dna Repair As Well As Survival Functions Of Mcl-1 Enhances Cancer Cell Killing
  1644. Targeting Tslp-Induce Upregulation Of Mcl-1 For The Treatment Of Ph-Like All With Crlf2 Alterations
  1645. Taz Promotes Temozolomide Resistance By Upregulating Mcl-1 In Human Glioma Cells
  1646. T-Cell Lymphoma And Adult T-Cell Leukemia/Lymphoma Cells Partially Depends On Up-Regulation Of Noxa, Functional Repression Of Mcl-1, And Down-Regulation Of …
  1647. Telomerase-Dependent Oncolytic Adenovirus Sensitizes Human Osteosarcoma Cells To Chemotherapy Through Mcl-1 Downregulation
  1648. Tertiary Structural Motif Sequence Statistics Enable Facile Prediction And Design Of Peptides That Bind Anti-Apoptotic Bfl-1 And Mcl-1
  1649. Tertiary Structural Motif Sequence Statistics Enable Rapid Discovery Of Novel Ligands For Anti-Apoptotic Bfl-1 And Mcl-1
  1650. The Akt/Mcl-1 Pathway Plays A Prominent Role In Mediating Antiapoptotic Signals Downstream Of The B-Cell Receptor In Chronic Lymphocytic Leukemia B Cells
  1651. The Akt/Mcl-1 Pathway Plays A Prominent Role In Mediating Pro-Survival Signals Derived From The B-Cell Receptor In Chronic Lymphocytic Leukemia B-Cells.
  1652. The Anti-Apoptotic Bcl-2 Family Member Mcl-1 Promotes T Lymphocyte Survival At Multiple Stages
  1653. The Antiapoptotic Effect Of Il-6 Autocrine Loop In A Cellular Model Of Advanced Prostate Cancer Is Mediated By Mcl-1
  1654. The Anti-Apoptotic Effect Of Leukotriene B4 In Neutrophils: A Role For Phosphatidylinositol 3-Kinase, Extracellular Signal-Regulated Kinase And Mcl-1
  1655. The Antiapoptotic Gene Mcl-1 Is Up-Regulated By The Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Through A Transcription Factor Complex Containing Creb
  1656. The Antiapoptotic Member Of The Bcl-2 Family Mcl-1 Is A Ctl Target In Cancer Patients
  1657. The Antiapoptotic Protein Mcl-1 Controls The Type Of Cell Death In Theiler’S Virus-Infected Bhk-21 Cells
  1658. The Anti-Apoptotic Protein Mcl-1 Inhibits Mitochondrial Ca2+ Signals
  1659. The Anti-Apoptotic Protein Mcl-1 Is An Important Regulator Of Mitochondrial Turnover
  1660. The Antiapoptotic Protein Mcl-1 Is Essential For The Survival Of Neutrophils But Not Macrophages
  1661. The Anti-Apoptotic Protein Mcl-1 Is Overexpressed In Prostate Cancer
  1662. The Anti-Apoptotic Role Of Interleukin-6 In Human Cervical Cancer Is Mediated By Up-Regulation Of Mcl-1 Through A Pi 3-K/Akt Pathway
  1663. The Apoptosis And Proliferation Of Sac-Activated B Cells By Il-10 Are Associated With Changes In Bcl-2, Bcl-Xl, And Mcl-1 Expression
  1664. The Apoptotic Response Of High‐Grade Serous Ovarian Cancers With Ccne1 Amplification To Paclitaxel In Vitro By Targeting Apc/C And The Pro‐Survival Protein Mcl‐1
  1665. The Bcl-2 Family Members Mcl-1 And Bim Modulate Apoptosis In Glutamine-Deprived Sp2/0-Ag14 Mouse Cells
  1666. The Bcl-2/Xl Inhibitor Abt-263 Increases The Stability Of Mcl-1 Mrna And Protein In Hepatocellular Carcinoma Cells
  1667. The Bh3 Mimetic Abt-737 Targets Selective Bcl-2 Proteins And Efficiently Induces Apoptosis Via Bak/Bax If Mcl-1 Is Neutralized
  1668. The Bh3 Α-Helical Mimic Bh3-M6 Disrupts Bcl-Xl, Bcl-2, And Mcl-1 Protein-Protein Interactions With Bax, Bak, Bad, Or Bim And Induces Apoptosis In A Bax-And Bim …
  1669. The Carboxyl-Terminal Tail Of Noxa Protein Regulates The Stability Of Noxa And Mcl-1
  1670. The Cd44 Adhesion Molecule By The Antibody A3D8 Induces And Enhances Drug-Induced Apoptosis In Acute Myeloid Leukemia Cells Through Down-Regulation Of Mcl-1.
  1671. The Cdk Inhibitor Purvalanol A Induces Neutrophil Apoptosis And Increases The Turnover Rate Of Mcl‐1: Potential Role Of P38‐Mapk In Regulation Of Mcl‐1 Turnover
  1672. The Cdk Inhibitor, R‐Roscovitine, Promotes Eosinophil Apoptosis By Down‐Regulation Of Mcl‐1
  1673. The Cdk5-Mcl-1 Axis Promotes Mitochondrial Dysfunction And Neurodegeneration In A Model Of Alzheimer’S Disease
  1674. The Cdk9 Inhibitor, Alvocidib, Potentiates The Non-Clinical Activity Of Azacytidine Or Decitabine In An Mcl-1-Dependent Fashion, Supporting Clinical Exploration Of A …
  1675. The Coffee Diterpene Kahweol Enhances Sensitivity To Sorafenib In Human Renal Carcinoma Caki Cells Through Down-Regulation Of Mcl-1 And C-Flip Expression
  1676. The Combination Of Reduced Mcl-1 And Standard Chemotherapeutics Is Tolerable In Mice
  1677. The Complex Mcl-1/Bim Regulates The Sensitivity Of Human Myeloma Cells To Melphalan.
  1678. The Coordinated Neutralization Of Bcl-Xl And Mcl-1 By Abt-737 In Combination With Radiation Treatment Leads To Enhanced Cytotoxicity In Nsclc Cells
  1679. The Cxcr4 Inhibitor Bl-8040 Induces The Apoptosis Of Aml Blasts By Downregulating Erk, Bcl-2, Mcl-1 And Cyclin-D1 Via Altered Mir-15A/16-1 Expression
  1680. The Cyclin-Dependent Kinase Inhibitor Flavopiridol Induces Apoptosis In Multiple Myeloma Cells Through Transcriptional Repression And Down-Regulation Of Mcl-1
  1681. The Cyclin‐Dependent Kinase Inhibitor R‐Roscovitine Down‐Regulates Mcl‐1 To Override Pro‐Inflammatory Signalling And Drive Neutrophil Apoptosis
  1682. The Cyclin-Dependent Kinase Inhibitor Sns-032 Induces Apoptosis In Breast Cancer Cells Via Depletion Of Mcl-1 And X-Linked Inhibitor Of Apoptosis Protein And …
  1683. The Design And Development Of Dual Mcl-1/Bcl-2 And Hdm2/Bcl-2 Protein Family Inhibitors Using A Polypharmacology Approach
  1684. The Discovery Of Small Molecule Chemical Probes Of Bcl-Xl And Mcl-1
  1685. The Downregulation Of Mcl-1 Via Usp9X Inhibition Sensitizes Solid Tumors To Bcl-Xl Inhibition
  1686. The Drug Combination Sorafenib And Quinacrine Targets The Expression Of Mcl-1-An Anti-Apoptotic Protein And Candidate Prognostic Factor In Anaplastic Thyroid Cancer …
  1687. The Dual Effects Of Tnfα On Neutrophil Apoptosis Are Mediated Via Differential Effects On Expression Of Mcl-1 And Bfl-1
  1688. The E3 Ubiquitin Ligases Β-Trcp And Fbxw7 Cooperatively Mediates Gsk3-Dependent Mcl-1 Degradation Induced By The Akt Inhibitor Api-1, Resulting In …
  1689. The Eat/Mcl-1 Gene, An Inhibitor Of Apoptosis, Is Up-Regulated In The Early Stage Of Acute Myocardial Infarction
  1690. The Effect Of N-Nitrosodimethylamine (Ndma) On Bax And Mcl-1 Expression In Human Neutrophils
  1691. The Effects Of Lentivirus-Mediated Shrna Interference Targeting Mcl-1 On Growth Of Nk/T-Cell Lymphoma.
  1692. The Effects Of Mcl-1 Gene On Atra-Resistant Hl-60 Cell
  1693. The Effects Of Thymoquinone On Viability, And Anti-Apoptotic Factors (Bcl-Xl, Bcl-2, Mcl-1) In Prostate Cancer (Pc3) Cells: An In Vitro And Computer …
  1694. The Enteroviral Capsid Protein Vp1 In The Islet Cells Of Patients With Type 1 Diabetes Is Associated With Induction Of Protein Kinase R And Downregulation Of Mcl-1
  1695. The Expression And Clinical Significances Of Mcl-1 In Cervical Cancer
  1696. The Expression Of Antiapoptotic Proteins Bcl-2, Bcl-Xl, And Mcl-1 In Benign, Dysplastic, And Malignant Biliary Epithelium
  1697. The Expression Of Cox-2 In Human Lung Cancer And Its Relationship With Expression Of K-Ras And Mcl-1.
  1698. The Expression Of Mcl-1 In Human Cervical Cancer And Its Clinical Significance
  1699. The Expressions And Clinical Significance Of Mcl-1 And Bar/Abl Genes In Chronic Myeloid Leukemia
  1700. The Fast-Mobility Isoform Of Mouse Mcl-1 Is A Mitochondrial Matrix-Localized Protein With Attenuated Anti-Apoptotic Activity
  1701. The First Mcl-1-Selective Bh3 Mimetics Have Therapeutic Potential For Chronic Lymphocytic Leukemia
  1702. The Foxm1-Induced Resistance To Oxaliplatin Is Partially Mediated By Its Novel Target Gene Mcl-1 In Gastric Cancer Cells
  1703. The Functional Role Of Mcl-1 In The Dynamics Of Mitotic Cell Fate.
  1704. The Hepatitis C Virus Core Protein Contains A Bh3 Domain That Regulates Apoptosis Through Specific Interaction With Human Mcl-1
  1705. The Human Stem Cell Hierarchy Is Defined By A Functional Dependence On Mcl-1 For Self-Renewal Capacity
  1706. The Imbalance Between Bim And Mcl‐1 Expression Controls The Survival Of Human Myeloma Cells
  1707. The Intracellular Distribution And Pattern Of Expression Of Mcl-1 Overlap With, But Are Not Identical To, Those Of Bcl-2.
  1708. The Involvement Of Pi 3-K/Akt-Dependent Up-Regulation Of Mcl-1 In The Prevention Of Apoptosis Of Hep3B Cells By Interleukin-6
  1709. The Kit D816V-Targeting Drug Pkc412 Induces Re-Expression Of Bim And Synergizes With Mcl-1 Antisense Oligonucleotides In Producing Growth Inhibition In …
  1710. The Lnc Rna Malat 1 Functions As A Competing Endogenous Rna To Regulate Mcl‐1 Expression By Sponging Mir‐363‐3P In Gallbladder Cancer
  1711. The Loss Of Mcl‐1 Expression In Human Polymorphonuclear Leukocytes Promotes Apoptosis
  1712. The Mcl-1 Bh3 Helix Is An Exclusive Mcl-1 Inhibitor And Apoptosis Sensitizer
  1713. The Mcl-1 Targeting Effect Of Alvocidib Potentiates The Activity Of Cytarabine And Mitoxantrone In A Time-Sequential Regimen In Aml
  1714. The Mtorc1/2 Inhibitor Azd8055 Strengthens The Efficiency Of The Mek Inhibitor Trametinib To Reduce The Mcl-1/[Bim And Puma] Ratio And To Sensitize Ovarian …
  1715. The Multikinase Inhibitor Sorafenib Potentiates Trail Lethality In Human Leukemia Cells In Association With Mcl-1 And Cflipl Down-Regulation
  1716. The Multi‐Kinase Inhibitor Tg 02 Overcomes Signalling Activation By Survival Factors To Deplete Mcl 1 And Xiap And Induce Cell Death In Primary Acute Myeloid …
  1717. The N Terminus Of The Anti-Apoptotic Bcl-2 Homologue Mcl-1 Regulates Its Localization And Function
  1718. The Novel Atp-Competitive Mek/Aurora Kinase Inhibitor Bi-847325 Overcomes Acquired Braf Inhibitor Resistance Through Suppression Of Mcl-1 And Mek Expression
  1719. The Novel Bmi-1 Inhibitor Ptc596 Downregulates Mcl-1 And Induces P53-Independent Mitochondrial Apoptosis In Acute Myeloid Leukemia Progenitor Cells
  1720. The Novel Cancer Drug Seliciclib Engages The Mitochondrial Apoptosis Pathway Via The Mcl-1/Noxa Axis In Cll.
  1721. The Noxa, Bim And Mcl-1 Axis Mediates Apoptosis In Response To General Metabolic Stress
  1722. The Noxa/Mcl-1 Axis Regulates Susceptibility To Apoptosis Under Glucose Limitation In Dividing T Cells
  1723. The Phosphotidyl Inositol 3-Kinase/Akt Signal Pathway Is Involved In Interleukin-6-Mediated Mcl-1 Upregulation And Anti-Apoptosis Activity In Basal Cell …
  1724. The Pi3 Kinase Inhibitor Nvp-Bkm120 Induces Gsk3/Fbxw7-Dependent Mcl-1 Degradation, Contributing To Induction Of Apoptosis And Enhancement Of Trail …
  1725. The Polyamines Regulate Endothelial Cell Survival During Hypoxic Stress Through Pi3K/Akt And Mcl-1
  1726. The Possible Role Of Apoptosis-Suppressing Genes, Bcl-2 And Mcl-1/Eat In Human Adrenal Tumors
  1727. The Protein Kinase Cδ Catalytic Fragment Targets Mcl-1 For Degradation To Trigger Apoptosis
  1728. The Raf Kinase Inhibitor Bay 43-9006 Accelerates Mcl-1 Degradation And Regulates Pro-Apoptotic Function
  1729. The Ratio Of Mcl-1 And Noxa Determines Abt737 Resistance In Squamous Cell Carcinoma Of The Skin
  1730. The Regulatory Role Of Mcl-1 In Apoptosis Of Mouse Peritoneal Macrophage Infected With M. Tuberculosis Strains That Differ In Virulence
  1731. The Relationship Between The Expression Of Mcl-1, Bax And Histologic Grade, Prognosis In Human Hepatocellular Carcinoma
  1732. The Relevance Of Sequence Insertions In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia And In Normal Cells
  1733. The Role Of Glucocorticoid Receptor Phosphorylation In Mcl-1 And Noxa Gene Expression
  1734. The Role Of Hectd1 And Mcl-1 In The Regulation Of Normal And Malignant Haematopoiesis
  1735. The Role Of Mcl-1 Downregulation In The Proapoptotic Activity Of The Multikinase Inhibitor Bay 43-9006
  1736. The Role Of Mcl-1 Expression And Phosphorlyation In Resistance To Chemotherapy And Kinase Inhibitors In Flt3-Itd-Positive Acute Myeloid Leukemia (Aml)
  1737. The Role Of Mcl-1 In S. Aureus-Induced Cytoprotection Of Infected Macrophages
  1738. The Role Of Mcl-1 In The Heart: Gateway From Life To Death
  1739. The Role Of Mcl-1 In The Response Of Human Colorectal Cancer Cells To Treatment With Dichloroacetate
  1740. The Role Of Noxa/Mcl-1 Axis In Solid Tumors Treated With Dna Damaging Agents
  1741. The Role Of Noxa/Mcl-1 In Head And Neck Squamous Cell Carcinoma (Hnscc) Treatment
  1742. The Roles Of Mcl-1 And Bcl-X In Central Nervous System Development
  1743. The Roles Of The Anti-Apoptotic Proteins Bcl-2 And Mcl-1 In The Survival Of The Cells Of The Immune System
  1744. The Secret Of Mim: A Novel, Mcl-1-Specific Small Molecule
  1745. The Sensitivity Of Ovarian Cancer Cells To The Hdac Inhibitor Belinostat Is Improved By Inhibiting Bcl-Xl Or Mcl-1 Anti-Apoptotic Proteins
  1746. The Sf3B1 Inhibitor Spliceostatin A (Ssa) Elicits Apoptosis In Chronic Lymphocytic Leukaemia Cells Through Downregulation Of Mcl-1
  1747. The Small Molecule Bcl-2/Mcl-1 Inhibitor Tw-37 Shows Single-Agent Cytotoxicity In Neuroblastoma Cell Lines
  1748. The Stress Protein Bag3 Stabilizes Mcl-1 Protein And Promotes Survival Of Cancer Cells And Resistance To Antagonist Abt-737
  1749. The Study Of The Effect Of Curcumin On Apoptosis-Regulating Protein Mcl-1, Bax And Bak In Acute Myeloid Leukemia Hl-60 Cell Line
  1750. The Tyrosine Kinase Syk Regulates Survival Of Chronic Lymphocytic Leukemia B Cells Through Pkcδ Phosphorylation And Proteasome-Dependent Regulation Of Mcl-1 …
  1751. The Tyrosine Kinase Syk Regulates The Survival Of Chronic Lymphocytic Leukemia B Cells Through Pkcδ And Proteasome-Dependent Regulation Of Mcl-1 …
  1752. The Vtlisfg Motif In The Bh1 Domain Plays A Significant Role In Regulating The Degradation Of Mcl-1
  1753. Therapeutic Efficacy Of Mcl-1 Antagonism In Large Granular Lymphocyte Leukemia
  1754. Therapeutic Inhibition Of Mcl-1 Blocks Cell Survival In Estrogen Receptor-Positive Breast Cancers
  1755. Therapeutic Potential Of Bcl-Xl/Mcl-1 Synthetic Inhibitor Jy-1-106 And Retinoids For Human Triple-Negative Breast Cancer Treatment
  1756. Thioridazine Enhances Sensitivity To Carboplatin In Human Head And Neck Cancer Cells Through Downregulation Of C-Flip And Mcl-1 Expression
  1757. Thr 163 Phosphorylation Causes Mcl-1 Stabilization When Degradation Is Independent Of The Adjacent Gsk3-Targeted Phosphodegron, Promoting Drug …
  1758. Thymic Stromal Lymphopoietin Interferes With The Apoptosis Of Human Skin Mast Cells By A Dual Strategy Involving Stat5/Mcl-1 And Jnk/Bcl-Xl
  1759. Tic10/Onc201 Synergizes With Bcl-2/Bcl-Xl Inhibition In Glioblastoma By Suppression Of Mcl-1 And Its Binding Partners In Vitro And In Vivo
  1760. Timed Degradation Of Mcl-1 Controls Mitotic Cell Death
  1761. Tipping The Noxa/Mcl-1 Balance Overcomes Abt-737 Resistance In Chronic Lymphocytic Leukemia
  1762. Titelbild: Deactivation Of Mcl‐1 By Dual‐Function Small‐Molecule Inhibitors Targeting The Bcl‐2 Homology 3 Domain And Facilitating Mcl‐1 Ubiquitination (Angew …
  1763. Tivantinib (Arq 197) Affects The Apoptotic And Proliferative Machinery Downstream Of C-Met: Role Of Mcl-1, Bcl-Xl And Cyclin B1
  1764. Tlr9 Signaling Delays Neutrophil Apoptosis By Increasing Transcription Of Mcl-1
  1765. Tofa (5-Tetradecyl-Oxy-2-Furoic Acid) Reduces Fatty Acid Synthesis, Inhibits Expression Of Ar, Neuropilin-1 And Mcl-1 And Kills Prostate Cancer Cells Independent Of P53 …
  1766. Toll-Like Receptor 9 Signaling Delays Neutrophil Apoptosis By Increasing Transcription Of Mcl-1
  1767. Toward Targeting Antiapoptotic Mcl-1 For Cancer Therapy
  1768. Toward Understanding Mcl-1 Promiscuous And Specific Binding Mode
  1769. Toxoplasma Gondii Induces Autophagy And Apoptosis In Human Umbilical Cord Mesenchymal Stem Cells Via Downregulation Of Mcl−1
  1770. Tp53 Deficient/Mutant Amls Are Resistant To Individual Bh3 Mimetics: High Efficacy Of Combined Inhibition Of Bcl-2 And Mcl-1
  1771. Trail And Proteasome Inhibitors Combination Induces A Robust Apoptosis In Human Malignant Pleural Mesothelioma Cells Through Mcl-1 And Akt Protein …
  1772. Trail Enhances Proteasome Inhibitor-Induced Apoptosis In Human Malignant Pleural Mesothelioma Cells Through Promoting Caspase Activation And Mcl-1 …
  1773. Trail Resistance Through Transcriptional Control Of Mcl-1
  1774. Trail-Activated Stress Kinases Suppress Apoptosis Through Transcriptional Upregulation Of Mcl-1
  1775. Trailr Triggering By Human Antibodies Induces Apoptosis Through An Early Cleavage Of Mcl-1 And Caspase 3 In Myeloma Cells.
  1776. Transcriptional And Translational Control Of Mcl-1 During Apoptosis
  1777. Transcriptional Regulation Of Mcl-1 Plays An Important Role Of Cellular Protective Effector Of Vincristine-Triggered Autophagy In Oral Cancer Cells
  1778. Transcriptional Silencing Of Mcl-1 Through Cyclin-Dependent Kinase Inhibition In Acute Myeloid Leukemia
  1779. Translation Inhibition During Cell Cycle Arrest And Apoptosis: Mcl-1 Is A Novel Target For Rna Binding Protein Cugbp2
  1780. Translation Inhibitors Induce Cell Death By Multiple Mechanisms And Mcl-1 Reduction Is Only A Minor Contributor
  1781. Translational Repression Of Mcl-1 Couples Stress-Induced Eif2Α Phosphorylation To Mitochondrial Apoptosis Initiation
  1782. Treatment With Homoharringtonine Reduces Levels Of Bcr-Abl, Mcl-1, And Hsp90 In Leukemia Cell Lines And The Survival Of Leukemic Stem Cells
  1783. Trichomonas Vaginalis Promotes Apoptosis Of Human Neutrophils By Activating Caspase‐3 And Reducing Mcl‐1 Expression
  1784. Trichonomas Vaginalis Metalloproteinase Induces Apoptosis Of Siha Cells Through Disrupting The Mcl-1/Bim And Bcl-Xl/Bim Complexes
  1785. Trim17-Mediated Ubiquitination And Degradation Of Mcl-1 Initiate Apoptosis In Neurons
  1786. Triptolide Induces Apoptotic Cell Death Of Multiple Myeloma Cells Via Transcriptional Repression Of Mcl-1
  1787. Tsc2+/-Eμ-Myc Tsc2+/-Eμ-Myc Shfluc. 1309 Mcl-1 Shbim. 764 Shbim. 825
  1788. Tyrosine Kinase Inhibitor (Tki) Exel-0862 Potently Induces Apoptosis In Human Fip1L1-Pdgfr-Α-Expressing Cells Through Caspase-Dependent Cleavage Of Mcl-1 …
  1789. Tyrosine Kinase Inhibitor Tyrphostin Ag490 Triggers Both Apoptosis And Autophagy By Reducing Hsf1 And Mcl-1 In Pel Cells
  1790. Ubiquitin-Independent Degradation Of Antiapoptotic Mcl-1
  1791. Umi-77 Primes Glioma Cells For Trail-Induced Apoptosis By Unsequestering Bim And Bak From Mcl-1
  1792. Understanding Bcl-Xl And Mcl-1 Gain-Of-Function (Gof) Inhibition Mechanism In Relation To Mitochondrial Metabolic Changes
  1793. Understanding The Species Selectivity Of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors
  1794. Unexpected Complexity In Mcl-1 Phosphorylation In Response To Microtubule Inhibitors.
  1795. Unique Biology Of Mcl-1: Therapeutic Opportunities In Cancer
  1796. Unraveling Mcl-1 Degradation
  1797. Up-Regulation Of Cdk9 Kinase Activity And Mcl-1 Stability Contributes To The Acquired Resistance To Cyclin-Dependent Kinase Inhibitors In Leukemia
  1798. Upregulation Of Mapk/Mcl-1 Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance To Bcl-2 Inhibitor Venetoclax In Aml
  1799. Up-Regulation Of Mcl-1 And Bak By Coronavirus Infection Of Human, Avian And Animal Cells Modulates Apoptosis And Viral Replication
  1800. Upregulation Of Mcl-1 Inhibits Jq1-Triggered Anticancer Activity In Hepatocellular Carcinoma Cells
  1801. Up-Regulation Of Mcl-1 Is Critical For Survival Of Human Melanoma Cells Upon Endoplasmic Reticulum Stress
  1802. Up-Regulation Of Pro-Apoptotic Protein Bim And Down-Regulation Of Anti-Apoptotic Protein Mcl-1 Cooperatively Mediate Enhanced Tumor Cell Death Induced By The …
  1803. Ursolic Acid Facilitates Apoptosis In Rheumatoid Arthritis Synovial Fibroblasts By Inducing Sp1-Mediated Noxa Expression And Proteasomal Degradation Of Mcl-1
  1804. Use Of A Mcl-1 Inhibitor Alone To De-Bulk Melanoma And In Combination To Kill Melanoma Initiating Cells
  1805. Using Cetsa Assay And A Mathematical Model To Reveal Dual Bcl-2/Mcl-1 Inhibition And On-Target Mechanism For Abt-199 And S1
  1806. Usp9X-And Noxa-Mediated Mcl-1 Downregulation Contributes To Pemetrexed-Induced Apoptosis In Human Non-Small-Cell Lung Cancer Cells
  1807. Vaccinia Virus F1L Interacts With Bak Using Highly Divergent Bcl-2 Homology Domains And Replaces The Function Of Mcl-1
  1808. Vascular Endothelial Growth Factor (Vegf) Is A Survival Factor In Metastatic Human Prostate Cancer Cells Via Induction Of Myeloid Cell Leukemia-1 (Mcl-1)
  1809. Vegf Induces Mcl-1 Up-Regulation And Protects Multiple Myeloma Cells Against Apoptosis
  1810. Vegf Upregulates Mcl-1 Expression And Protects Multiple Myeloma Cells Against Starvation Induced-Apoptosis.
  1811. Vesicular Stomatitis Virus Induces Apoptosis Primarily Through Bak Rather Than Bax By Inactivating Mcl-1 And Bcl-Xl
  1812. Vinblastine Induces Acute, Cell Cycle Phase–Independent Apoptosis In Some Leukemias And Lymphomas And Can Induce Acute Apoptosis In Others When Mcl-1 Is …
  1813. Vinca Alkaloids Cause Aberrant Ros-Mediated Jnk Activation, Mcl-1 Downregulation, Dna Damage, Mitochondrial Dysfunction, And Apoptosis In Lung Adenocarcinoma …
  1814. Virtual Screening For Inhibitors Of Anti-Apoptotic Proteins: Dck, Bcl-Xl, Mcl-1, Mdmx, And Mdm2
  1815. Virtual Screening For Potential Inhibitors Of Mcl-1 Conformations Sampled By Normal Modes, Molecular Dynamics, And Nuclear Magnetic Resonance
  1816. Virtual Screening, Docking Study And Molecular Dynamics (Md) Simulation Approach To Identify Inhibitors With Novel Scaffolds For Myeloid Cell Leukemia (Mcl-1 …
  1817. Voruciclib, A Clinical Stage Oral Cdk9 Inhibitor, Represses Mcl-1 And Sensitizes High-Risk Diffuse Large B-Cell Lymphoma To Bcl2 Inhibition
  1818. Vsv Virotherapy Improves Chemotherapy By Triggering Apoptosis Due To Proteasomal Degradation Of Mcl-1
  1819. Vsv Virotherapy Of Tumors Enhances Chemotherapeutic Efficacy By Proteasomal Degradation Of Mcl-1
  1820. Wee-1 Kinase Inhibition Sensitizes High-Risk Hpv+ Hnscc To Apoptosis Accompanied By Downregulation Of Mcl-1 And Xiap Antiapoptotic Proteins
  1821. Weight Glycoprotein Fraction From Ganoderma Lucidum Inhibits The Akt Pathway In Resistant Myeloma Cell Lines Decreasing Mcl-1 Expression, Up-Regulating Fkhr …
  1822. Wogonin And Related Natural Flavones Are Inhibitors Of Cdk9 That Induce Apoptosis In Cancer Cells By Transcriptional Suppression Of Mcl-1
  1823. Xanthohumol Induces Apoptosis In B-Cll Mediated By Caspase 9 Following Downregulation Of Bcl-Xl And Mcl-1.
  1824. Xpo1 Inhibitor Kpt-330 Synergizes With Bcl-Xl Inhibitor To Induce Cancer Cell Apoptosis By Perturbing Rrna Processing And Mcl-1 Protein Synthesis
  1825. Ym155 Enhances Abt-737-Mediated Apoptosis Through Mcl-1 Downregulation In Mcl-1-Overexpressed Cancer Cells
  1826. Ym155 Exerts Potent Cytotoxic Activity Against Quiescent (G0/G1) Multiple Myeloma And Bortezomib Resistant Cells Via Inhibition Of Mcl-1 And Survivin
  1827. Ym155 Exerts Potent Cytotoxic Activity Against Quiescent (G0/G1) Multiple Myeloma And Bortezomib Resistant Cells Via Inhibition Of Survivin And Mcl-1
  1828. Ym155 Induces Apoptosis Through Proteasome-Dependent Degradation Of Mcl-1 In Primary Effusion Lymphoma
  1829. Ym155 Induces Caspase-8 Dependent Apoptosis Through Downregulation Of Survivin And Mcl-1 In Human Leukemia Cells
  1830. Ym-155 Potentiates The Effect Of Abt-737 In Malignant Human Glioma Cells Via Survivin And Mcl-1 Downregulation In An Egfr-Dependent Context
  1831. Ym-155 Sensitizes Malignant Human Glioma Cells To Abt-737 Via Survivin And Mcl-1 Downregulation In An Egfr-Dependent Context.
  1832. Ym155 Sensitizes Trail-Induced Apoptosis Through Cathepsin S-Dependent Down-Regulation Of Mcl-1 And Nf-Κb-Mediated Down-Regulation Of C-Flip …
  1833. Zoledronic Acid Increases Docetaxel Cytotoxicity Through Pmek And Mcl-1 Inhibition In A Hormone-Sensitive Prostate Carcinoma Cell Line
  1834. Α-Tocopherol Impairs 7-Ketocholesterol-Induced Caspase-3-Dependent Apoptosis Involving Gsk-3 Activation And Mcl-1 Degradation On 158N Murine Oligodendrocytes
  1835. Βarrestin-1 And Mcl-1 Modulate Self-Renewal Growth Of Cancer Stem-Like Side-Population Cells In Non-Small Cell Lung Cancer
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