User Image Cart Icon 0 Search Image
  • Home > Blog > (Sirt1 | Sirt 1) (Activator | Activators | Activation)

(Sirt1 | Sirt 1) (Activator | Activators | Activation)

  1. SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages
  2. Sirt 1 activator inhibits the AGE-induced apoptosis and p53 acetylation in human vascular endothelial cells
  3. Cardiovascular effects of a novel SIRT 1 activator, SRT 2104, in otherwise healthy cigarette smokers
  4. The SIRT1 activator resveratrol protects SK‐N‐BE cells from oxidative stress and against toxicity caused by α‐synuclein or amyloid‐β (1‐42) peptide
  5. Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase
  6. Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis
  7. SIRT 1‐mediated epigenetic downregulation of plasminogen activator inhibitor‐1 prevents vascular endothelial replicative senescence
  8. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
  9. Treadmill exercise decreases amyloid-β burden possibly via activation of SIRT-1 signaling in a mouse model of Alzheimer’s disease
  10. Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity
  11. A novel biological role of α‐mangostin in modulating inflammatory response through the activation of SIRT‐1 signaling pathway
  12. Two novel SIRT1 activators, SCIC2 and SCIC2. 1, enhance SIRT1-mediated effects in stress response and senescence
  13. Peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial …
  14. SIRT1/PGC-1 pathway activation triggers autophagy/mitophagy and attenuates oxidative damage in intestinal epithelial cells
  15. Probing the mechanism of SIRT1 activation by a 1, 4-dihydropyridine
  16. Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway
  17. Involvement of TACE in colon inflammation: a novel mechanism of regulation via SIRT-1 activation
  18. Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection
  19. Pharmacokinetics and tolerability of SRT 2104, a first‐in‐class small molecule activator of SIRT 1, after single and repeated oral administration in man
  20. Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in mice
  21. PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis
  22. SIRT1 silencing confers neuroprotection through IGF‐1 pathway activation
  23. Induction of autophagy and activation of SIRT‐1 deacetylation mechanisms mediate neuroprotection by the pomegranate metabolite urolithin A in BV2 microglia and …
  24. SirT1 activator represses the transcription of TNF‑α in THP‑1 cells of a sepsis model via deacetylation of H4K16
  25. Parthenolide Phytosomes Attenuated Gentamicin-Induced Nephrotoxicity in Rats via Activation of Sirt-1, Nrf2, OH-1, and NQO1 Axis
  26. SIRT 1 activator loaded inhaled antiangiogenic liposomal formulation development for pulmonary hypertension
  27. Oligo-fucoidan improves diabetes-induced renal fibrosis via activation of sirt-1, glp-1r, and nrf2/ho-1: An in vitro and in vivo study
  28. Inhibition of SIRT1 by HIV-1 viral protein Tat results in activation of p53 pathway
  29. α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase
  30. Sirt 1 activator attenuates the bleomycin-induced lung fibrosis in mice via inhibiting epithelial-to-mesenchymal transition (EMT).
  31. Homocysteine facilitates LOX-1 activation and endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human hyperhomocysteinaemia
  32. … Effect of DiDang Tang Against AlCl3-Induced Oxidative Stress and Apoptosis in PC12 Cells Through the Activation of SIRT1-Mediated Akt/Nrf2/HO-1 …
  33. AMPK inhibits MTDH expression via GSK 3β and SIRT 1 activation: potential role in triple negative breast cancer cell proliferation
  34. Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation
  35. A pharmacological review on SIRT 1 and SIRT 2 proteins, activators, and inhibitors: Call for further research
  36. … dysfunction by cantleyoside confines inflammatory response and promotes apoptosis of human HFLS-RA cell line via AMPK/Sirt 1/NF-κB pathway activation
  37. Low-frequency electroacupuncture improves insulin sensitivity in obese diabetic mice through activation of SIRT1/PGC-1 in skeletal muscle
  38. Activating SIRT-1 Signalling with the Mitochondrial-CoQ10 Activator Solanesol Improves Neurobehavioral and Neurochemical Defects in Ouabain-Induced …
  39. Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways
  40. Activation of SIRT-1 Signalling in the Prevention of Bipolar Disorder and Related Neurocomplications: Target Activators and Influences on Neurological Dysfunctions
  41. Thymoquinone ameliorates diabetic phenotype in Diet-Induced Obesity mice via activation of SIRT-1-dependent pathways
  42. N1-Methylnicotinamide Improves Hepatic Insulin Sensitivity via Activation of SIRT1 and Inhibition of FOXO1 Acetylation
  43. Resveratrol-mediated SIRT-1 interactions with p300 modulate receptor activator of NF-κB ligand (RANKL) activation of NF-κB signaling and inhibit …
  44. Resveratrol inhibits the hydrogen dioxide-induced apoptosis via Sirt 1 activation in osteoblast cells
  45. … IIA sulfonate protects against hyperhomocysteine-induced vascular endothelial injury via activation of NNMT/SIRT1-mediated NRF2/HO-1 and AKT/MAPKs …
  46. … ischemia–reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation
  47. Aloin reduces HMGB1-mediated septic responses and improves survival in septic mice by activation of the SIRT1 and PI3K/Nrf2/HO-1 signaling axis
  48. … ethanolic extract attenuates chronic restraint stress aggravated DSS-induced ulcerative colitis in mice via inhibition of NF-κB/STAT3 and activation of HO-1/Nrf2/SIRT1 …
  49. Activation of AMPK-dependent SIRT-1 by astragalus polysaccharide protects against ochratoxin A-induced immune stress in vitro and in vivo
  50. … confers neuroprotection against hypoxia-ischemia induced brain damage in neonatal rats via autophagy and silent information regulator 1 (SIRT1) activation
  51. Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1
  52. … M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1
  53. 1, 25-Dihydroxyvitamin D decreases tertiary butyl-hydrogen peroxide-induced oxidative stress and increases AMPK/SIRT1 activation in C2C12 muscle cells
  54. Grape seed proanthocyanidins prevent H2O2‐induced mitochondrial dysfunction and apoptosis via SIRT 1 activation in embryonic kidney cells
  55. Activation of SIRT-1 Pathway by Nanoceria Sheds Light on Its Ameliorative Effect on Doxorubicin-Induced Cognitive Impairment (Chemobrain): Restraining Its …
  56. SIRT1 protects against aortic dissection by regulating AP-1/decorin signaling-mediated PDCD4 activation
  57. … the expression of adiponectin in 3T3-L1 adipocytes via the activation of silent mating type information regulation 2 homologue 1 (SIRT1)-deacetylase and peroxisome …
  58. Avasimibe and Sirt 1 Activators Reverse NAFLD and Obesity.
  59. … sulfate promotes arterial thrombosis in rat model via increased levels of complex TF/VII, PAI-1, platelet activation as well as decreased contents of SIRT1 and …
  60. Corylin reduces obesity and insulin resistance and promotes adipose tissue browning through SIRT-1 and β3-AR activation
  61. Sirt1 regulates microglial activation and inflammation following oxygen-glucose deprivation/reoxygenation injury by targeting the Shh/Gli-1 signaling pathway
  62. … inhibits hypoxia‐inducible factor‐1 alpha and carbonic anhydrase expression through activation of AMP‐activated protein kinase/HO‐1/Sirt1 pathway in glioblastoma …
  63. Dysregulation of SIRT-1 signaling in multiple sclerosis and neuroimmune disorders: a systematic review of sirtuin activators as potential immunomodulators and their …
  64. Discovery of Imidazo[1,2-b]thiazole Derivatives as Novel SIRT1 Activators
  65. A series of novel indazole derivatives of Sirt 1 activator as osteogenic regulators
  66. Fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through USP22/Sirt 1
  67. … Mellitus by Activating Monophosphate-Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Axis and Inhibiting Nuclear Factor-kappa B (NF-κB) Activation
  68. … acid inhibits insulin-induced activation of sterol regulatory-element binding protein 1 and cyclooxygenase-2 expression through upregulation of SIRT1 in human colon …
  69. Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1
  70. SIRT-1 ACTIVATORS–IN DIABETIC NEPHROPATHY
  71. Amelioration of high-fat diet (HFD)+ CCl4 induced NASH/NAFLD in CF-1 mice by activation of SIRT-1 using cinnamoyl sulfonamide hydroxamate derivatives …
  72. Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation
  73. HIC2, a new transcription activator of SIRT1
  74. Synthesis of four SIRT1 activators based on an imidazo [1, 2-b] thiazole structure, in vitro derived metabolites and deuterated analogs
  75. Integrated ligand and structure-based investigation of structural requirements for silent information regulator 1 (SIRT1) activation
  76. Solanesol Mediated SIRT-1 Activation Prevents Neurobehavioral and Neurochemical Defects in Ouabain-Induced Experimental Model of Bipolar Disorder in Rats
  77. Solanesol Mediated SIRT-1 Signaling Activation Prevents Neurobehavioral and Neurochemical Defects in Ouabain-induced Experimental Model of Bipolar Disorder …
  78. Activation of Sirtuin 1 (SIRT1) Signaling by Resveratrol Increases Human Beta‐Defensins‐2 and‐3 (HBD2, HBD3) Production in Response to Lipopolysaccharide …
  79. Silent Information Regulator 1 (SIRT1) Promotes Pancreatic β-Cell Mitochondrial Autophagy and Pyrin Domains-Containing Protein 3 (NLRP3) Activation Under High …
  80. Identification and molecular modeling of novel endogenous activator proteins of Sirt-1: an in silico study.
  81. SIRT-1 ACTIVATOR RESVERATROL PROTECTS HUVECs FROM HIGH GLUCOSE-DEPENDENT REDOX AND GLYCATIVE IMBALANCES
  82. INVESTIGATION OF SIRT-1 ACTIVATOR IN INTRACEREBROPEDUNCLE ETHIDIUM BROMIDE INDUCED EXPERIMENTAL MODEL OF MULTIPLE SCLEROSIS IN …
  83. Cardiovascular Effects of a Novel SIRT 1 Activator, SRT2104, in Otherwise Healthy Cigarette Smokers
  84. Cardiovascular effects of the treatments for diabetes mellitus: the effect of SIRT-1 activation on markers of endothelial function, arterial stiffness and thrombosis; and …
  85. … OF NOVEL 4-THIAZOLIDINONE DERIVATIVES BEARING 1, 3, 4-OXADIAZOLE MOIETY AS SIRT-3 ACTIVATORS TARGETING PARKINSON’S DISEASE
  86. SirT1 blocks apoptosis in human chondrocytes via activation of the IGF-1 Receptor/Akt pathway
  87. GW25-e1524 SIRT1-Mediated Epigenetic Downregulation of Plasminogen Activator Inhibitor-1 Prevents Vascular Endothelial Replicative Senescence
  88. Ligand docking suggests isomer specific catechin induced SIRT‐1 activation
  89. … modeling, Molecular Dynamic Simulation and in silico screening of Activator for the Intensification of human sirtuin type 1 (SIRT1) by novel 1, 3, 4-thiadiazole …
  90. Treadmill exercise upregulates the non-amyloidogenic pathway and inhibits amyloid-b production via activation of SIRT-1 signaling in a mouse model of Alzheimer’s …
  91. Activation of a class-III histone deacetylase, SIRT1, prevents the oxidative-stress mediated cell-death by suppressing the activity of poly (ADP) ribose polymerase-1
  92. Sirt-1 Induces Vascular Endothelial Growth Factor Through The Activation of HIF-2α In Hypoxia
  93. Endothelial LOX-1 Protects Against Arterial Thrombosis via Activation of the Oct-1/SIRT1 Pathway
  94. Hsp90 inhibition suppresses NF-kB transcriptional activation via Sirt-2 in human 1 lung microvascular endothelial cells. 2
  95. Activation of the AKT Pathway Mediates Upregulation of Hif-1α and Sirt1 via Downregulation of miR-199a and is Neutralized by Beta-adrenergic Stimulation
  96. Paeonol attenuates high glucose-induced expression of FN and ICAM-1 by promoting the activation of Nrf2/ARE pathway via upregulation of Sirt1 in GMCs
  97. Synthesis and Yeast-based Screening of 1, 3-benzodioxole Derivatives for SIRT1 Activators
Related Posts

Hsp70, The Anti-aging Protein

Cold-inducible Rna-binding Protein (Cirbp) & Dna Repair

Anxiogenic

Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.

0
    0
    Your Cart
    Your cart is emptyReturn to Shop
    Continue Shopping