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Extracellular Matrix Stiffening (10th Hallmark of Aging)
Extracellular Matrix Stiffening (10th Hallmark of Aging)
EXTRACELLULAR GLYCATION crosslinks: prospects for removal
Attenuation of EXTRACELLULAR MATRIX accumulation in diabetic nephropathy by the advanced GLYCATION end product cross-link BREAKER ALT-711 via a protein kinase C-α …
Advanced GLYCATION endproduct CROSSLINKING in the cardiovascular system
Advanced GLYCATION End Product Cross‐Linking: Pathophysiologic Role and Therapeutic Target in Cardiovascular Disease
GLYCATION end-product cross-link BREAKER reduces collagen and improves cardiac function in AGING diabetic heart
Advanced GLYCATION end-product cross-link BREAKERs: a novel approach to cardiovascular pathologies related to the AGING process
Advanced GLYCATION endproduct crosslink BREAKER (alagebrium) improves endothelial function in patients with isolated systolic hypertension
BREAKERs of advanced GLYCATION end products restore large artery properties in experimental diabetes
Role of the AGE crosslink BREAKER, alagebrium, as a renoprotective agent in diabetes
Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy
A BREAKER of advanced GLYCATION end products attenuates diabetes-induced myocardial structural changes
Crosslink BREAKERs: a new approach to cardiovascular therapy
Advanced GLYCATION endproducts and osteoarthritis
Accumulation of advanced GLYCATION endproducts reduces chondrocyte-mediated EXTRACELLULAR MATRIX turnover in human articular cartilage
Cross-link BREAKERs as a new therapeutic approach to cardiovascular disease
Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of AGING and diabetes
The role of advanced GLYCATION end products in retinal ageing and disease
AGE-BREAKERs cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats
The AGE of the MATRIX: chemistry, consequence and cure
Advanced GLYCATION: an important pathological event in diabetic and age related ocular disease
The relationship between myocardial EXTRACELLULAR MATRIX remodeling and ventricular function
Importance of advanced GLYCATION end products in diabetes-associated cardiovascular and renal disease
Repairing EXTRACELLULAR AGING and GLYCATION
Novel inhibitors of advanced GLYCATION endproducts
Does accumulation of advanced GLYCATION end products contribute to the AGING phenotype?
The role of AGEs in AGING: causation or correlation
Diabetes and advanced GLYCATION endproducts
Role of advanced GLYCATION end products in diabetic nephropathy
Advanced GLYCATION end‐products (AGEs) and heart failure: pathophysiology and clinical implications
AGEing and osteoarthritis: a different perspective
Combination therapy with the advanced GLYCATION end product cross-link BREAKER, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or …
Characteristics, formation, and pathophysiology of glucosepane: a major protein cross-link
The breakdown of pre‐existing advanced GLYCATION end products is associated with reduced renal fibrosis in experimental diabetes
EXTRACELLULAR MATRIX maturation in the left ventricle of normal and diabetic swine
Inhibitors of the Maillard reaction and AGE BREAKERs as therapeutics for multiple diseases
Advanced GLYCATION end-products: implications for diabetic and non-diabetic nephropathies
The role of advanced GLYCATION end products in progression and complications of diabetes
AGE, RAGE, and ROS in diabetic nephropathy
Advanced GLYCATION endproducts (AGEs): pharmacological inhibition in diabetes
Prevention and Repair of Protein Damage by the Maillard Reaction In Vivo
Alagebrium chloride, a novel advanced GLYCATION end-product cross linkage BREAKER, inhibits neointimal proliferation in a diabetic rat carotid balloon injury …
Advanced GLYCATION end products: a Nephrologist’s perspective
Collagen cross-link BREAKERs: a beginning of a new era in the treatment of cardiovascular changes associated with AGING, diabetes, and hypertension
AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
Molecular mechanisms of ageing in connective tissues
Effects of alagebrium, an advanced GLYCATION end‐product BREAKER, in patients with chronic heart failure: study design and baseline characteristics of the BENEFICIAL …
Advanced GLYCATION end products and diabetic complications
Vascular AGING: from molecular mechanism to clinical significance
Advanced GLYCATION end products: sparking the development of diabetic vascular injury
Cardiac fibrosis and AGING
Role of advanced GLYCATION end products in diabetic neuropathy
Restraining cross-links responsible for the mechanical properties of collagen fibers: natural and artificial
Getting better without AGE: new insights into the diabetic heart
Arterial stiffness and EXTRACELLULAR MATRIX
Limited joint mobility in diabetes and ageing: recent advances in pathogenesis and therapy
Effects of advanced GLYCATION end-product inhibition and cross-link breakage in diabetic rats
An agent cleaving glucose-derived protein crosslinks in vitro and in vivo
Advanced GLYCATION end products, diabetes and ageing
The role of AGEs in cardiovascular disease
Effect of the age cross-link BREAKER alagebrium on anterior segment physiology, morphology, and ocular age and rage
Clinical studies of advanced GLYCATION end product inhibitors and diabetic kidney disease
Ultrasonic detection of the anisotropy of protein cross-linking in myocardium
TRC4149 a novel advanced GLYCATION end product BREAKER improves hemodynamic status in diabetic spontaneously hypertensive rats
Long-term exercise training attenuates age-related diastolic dysfunction: association of myocardial collagen cross-linking
Inhibitors and BREAKERs of advanced GLYCATION endproducts (AGEs): a review
The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy
Advanced GLYCATION end products and diabetic foot disease
Serum carboxymethyl–lysine, an advanced GLYCATION end product, is associated with increased aortic pulse wave velocity in adults
Mechanisms of maturation and ageing of collagen
Below the Radar: Advanced GLYCATION End Products that Detour “around the side”: Is HbA1c not an accurate enough predictor of long term progression and …
Advanced GLYCATION endproducts—role in pathology of diabetic complications
New therapies for advanced GLYCATION end product nephrotoxicity: current challenges
The role of advanced GLYCATION in the pathogenesis of diabetic retinopathy
Advanced GLYCATION end products and diabetic complications: a general overview
Advanced GLYCATION end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
Evolution and modulation of age-related medial elastocalcinosis: impact on large artery stiffness and isolated systolic hypertension
Agents that block advanced GLYCATION end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: a novel therapeutic strategy for diabetic vascular …
Ultrasonic detection of the anisotropy of protein cross linking in myocardium at diagnostic frequencies
Advanced GLYCATION end products and the progressive course of renal disease
Glucose, GLYCATION, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy
Protein CROSSLINKING by the maillard reaction with ascorbic acid and glucose
Green tea attenuates diabetes induced Maillard-type fluorescence and collagen cross-linking in the heart of streptozotocin diabetic rats
EXTRACELLULAR MATRIX changes and vascular smooth muscle signaling
Mechanisms, pathophysiology, and therapy of arterial stiffness
Inhibition of NADPH oxidase prevents advanced GLYCATION end product–mediated damage in diabetic nephropathy through a protein kinase C-α–dependent pathway
The effect of advanced GLYCATION end products (AGE) BREAKER, alagebrium on the cardiac structural and functional change in type I diabetic rat model
Glucose-mediated cross-linking of collagen in rat tendon and skin
The role of advanced GLYCATION end products in the development of atherosclerosis
Advanced GLYCATION end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines
Advanced GLYCATION end-products and arterial stiffness in hypertension
Beneficial effects of C36, a novel BREAKER of advanced GLYCATION endproducts cross‐links, on the cardiovascular system of diabetic rats
Advanced GLYCATION: implications in tissue damage and disease
Regulation of advanced GLYCATION end product (AGE)-receptor (RAGE) system by PPAR-gamma agonists and its implication in cardiovascular disease
Potential Usefulness of AGE Cross–Link BREAKERs for Modulating the Progression of AMD
Feasibility of using magnetic resonance elastography to study the effect of AGING on shear modulus of skeletal muscle
AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?
Advanced GLYCATION end product interventions reduce diabetes-accelerated atherosclerosis
GLYCATION and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control …
Arguing for the motion: yes, RAGE is a receptor for advanced GLYCATION endproducts
Oxidative stress and AGING: is methylglyoxal the hidden enemy?
Changes in bone collagen with age and disease
Advanced GLYCATION and ROS: a link between diabetes and heart failure
Methylglyoxal and advanced GLYCATION endproducts: new therapeutic horizons?
Trends in advanced GLYCATION end products research in diabetes mellitus and its complications
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711)
Diabetic nephropathy: important pathophysiologic mechanisms
Decreased plasma levels of soluble receptor for advanced GLYCATION end-products in patients with essential hypertension
Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects
LR-90 a new advanced GLYCATION endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats
Diabetic cardiomyopathy
AGE-RAGE and AGE Cross-link interaction: important players in the pathogenesis of diabetic kidney disease
Arterial AGING: a journey into subclinical arterial disease
AGING of myocardial collagen
Advanced GLYCATION end products and the kidney
Therapeutic potential of AGE inhibitors and BREAKERs of AGE protein cross-links
Reactive oxygen species amplify glucose signalling in renal cells cultured under high glucose and in diabetic kidney
The effects of the Maillard reaction on the physical properties and cell interactions of collagen
The clinical relevance of advanced GLYCATION endproducts (AGE) and recent developments in pharmaceutics to reduce AGE accumulation
Advanced GLYCATION end-products as a potential target for treatment of cardiovascular disease
Protein GLYCATION and Eye Diseases
Advanced GLYCATION and retinal pathology during diabetes
Advanced glycoxidation end products in chronic diseases—clinical chemistry and genetic background
Role of AGEs in diabetic nephropathy
Skin-autofluorescence, a measure of tissue advanced GLYCATION end-products (AGEs), is related to diastolic function in dialysis patients
Heart, AGING, and hypertension
Combination therapy with the AGE cross-link BREAKER, alagebrium and angiotensin converting enzyme inhibitors in diabetes: Synergy or redundancy
Microvascular Complications of Diabetes Mellitus
Advanced GLYCATION end products, oxidative stress and diabetic nephropathy
XLF-III-43, a novel coumarin–aspirin compound, prevents diabetic nephropathy in rats via inhibiting advanced GLYCATION end products
Advanced GLYCATION end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women
Pathophysiology, genetic, and therapy of arterial stiffness
Mechanisms of diastolic dysfunction in heart failure
Receptor for advanced GLYCATION endproducts and atherosclerosis: from basic mechanisms to clinical implications
AGING hearts and vessels: masters of adaptation and survival
The role of inflammatory and fibrogenic pathways in heart failure associated with AGING
Diastolic heart failure: mechanisms and controversies
RAGE signaling in inflammation and arterial AGING
Reversal of chaperone activity loss of glycated αA-crystallin by a crosslink BREAKER
Cells and tissue interactions with glycated collagen and their relevance to delayed diabetic wound healing
The clinical relevance of assessing advanced GLYCATION endproducts accumulation in diabetes
Alagebrium chloride, a novel AGE cross linkage BREAKER, inhibits neointimal proliferation after carotid balloon injury in diabetic animal model
Advanced GLYCATION end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor β-independent …
The AGE/RAGE axis in diabetes‐accelerated atherosclerosis
Advanced GLYCATION end products and diabetic nephropathy
The maillard reaction in eye diseases
Republished paper: arterial stiffness in chronic kidney disease: causes and consequences
Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced GLYCATION end products
Medical treatment of Marfan syndrome: a time for change
Oxidative stress, AGE, and atherosclerosis
Mechanisms of diabetic vasculopathy: an overview
The breakdown of preformed advanced GLYCATION end products reverses erectile dysfunction in streptozotocin‐induced diabetic rats: Preventive versus curative …
Accumulation of advanced GLYCATION end products as a molecular mechanism for AGING as a risk factor in osteoarthritis
Advanced GLYCATION and endothelial functions: a link towards vascular complications in diabetes
Advanced GLYCATION end-products and the progress of diabetic vascular complications
Advanced GLYCATION endproducts: a biomarker for age as an outcome predictor after cardiac surgery?
AntiGLYCATION properties of aged garlic extract: possible role in prevention of diabetic complications
GLYCATION—a sweet tempter for neuronal death
Advanced GLYCATION end-products: a review
The next generation of diabetic nephropathy therapies: an update
Clinical relevance of advanced GLYCATION endproducts for vascular surgery
Advanced GLYCATION end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study
Hyperglycemia and the pathobiology of diabetic complications
Arterial AGING: is it an immutable cardiovascular risk factor?
The receptor for advanced GLYCATION endproducts (RAGE) and cardiovascular disease
Interactions between advanced GLYCATION end-products (AGE) and their receptors in the development and progression of diabetic nephropathy-are these receptors …
Advanced glycosylated end products and hyperglycemia in the pathogenesis of diabetic complications
Advanced GLYCATION endproducts: activators of cardiac remodeling in primary fibroblasts from adult rat hearts
Diabetic heart disease
The road to advanced GLYCATION end products: a mechanistic perspective
Blockade of diabetic vascular injury by controlling of AGE-RAGE system
Clinical potential of advanced GLYCATION end-product inhibitors in diabetes mellitus
GLYCATION increases human annulus fibrosus stiffness in both experimental measurements and theoretical predictions
Phase I clinical studies of the advanced GLYCATION end-product (AGE)-BREAKER TRC4186
Protein GLYCATION: a firm link to endothelial cell dysfunction
Treating diastolic heart failure with AGE crosslink BREAKERs: thinking outside the heart failure box
MATRIX biology of abdominal aortic aneurysms in diabetes: mechanisms underlying the negative association
Advanced GLYCATION endproducts and rat dental implant osseointegration
AGEs induce oxidative stress and activate protein kinase C-βII in neonatal mesangial cells
Advanced GLYCATION end products and vascular structure and function
Nitrite-induced cross-linking alters remodeling and mechanical properties of collagenous engineered tissues
Do diabetes and hypertension interact to accelerate vascular ageing?
Molecular targets of diabetic cardiovascular complications
Skin autofluorescence, a marker for advanced GLYCATION end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease
Age associated changes of AGE-receptor expression: RAGE upregulation is associated with human heart dysfunction
Transition metal‐mediated glycoxidation accelerates cross‐linking of β‐amyloid peptide
Ventricular remodeling/fibrosis, renal arterial brachytherapy, collagen crosslink BREAKERs, salt, and therapeutic adherence
Effects of Compounds Isolated from the Fruits of Rumex japonicus on the Protein GLYCATION
Therapeutic interventions in the glyc (oxid) ation pathway
Skin autofluorescence is a strong predictor of cardiac mortality in diabetes
Modification of the effect of glycemic status on aortic distensibility by age in the multi-ethnic study of atherosclerosis
The role of AGEs and AGE inhibitors in diabetic cardiovascular disease
Clinical and prognostic value of advanced GLYCATION end-products in chronic heart failure
Glycosylation Inhibitors, PKC Inhibitors and Related Interventions Against Complications
Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options
Significance of advanced GLYCATION end products in AGING-related disease
The role of collagen crosslinks on passive cardiac mechanics in volume-overload hypertrophy
Dicarbonyls linked to damage in the powerhouse: GLYCATION of mitochondrial proteins and oxidative stress
Advanced GLYCATION end products and RAGE: a common thread in AGING, diabetes, neurodegeneration, and inflammation
Potential new therapeutic agents for diabetic kidney disease
TRC4186, a novel AGE-BREAKER, improves diabetic cardiomyopathy and nephropathy in Ob-ZSF1 model of type 2 diabetes
Accumulation of advanced GLYCATION end products and chronic complications in ESRD treated by dialysis
MATRIX metalloproteinase 2 activation of transforming growth factor-β1 (TGF-β1) and TGF-β1–type II receptor signaling within the aged arterial wall
Modulation of soluble receptor for advanced GLYCATION end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy
Advanced GLYCATION endproducts: what is their relevance to diabetic complications?
AGING and arterial stiffness
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice
Pyridoxamine, an inhibitor of advanced GLYCATION and lipoxidation reactions: a novel therapy for treatment of diabetic complications
Emerging concepts in cardiac MATRIX biology
Ageing of the conduit arteries
Fe2+-catalyzed non-enzymatic glycosylation alters collagen conformation during AGE-collagen formation in vitro
Microvascular complications of diabetes
Intervention against the Maillard reaction in vivo
Age-associated changes in cardiac MATRIX and integrins
Advanced GLYCATION end products and cardiovascular disease
Arterial AGING and subclinical arterial disease are fundamentally intertwined at macroscopic and molecular levels
The AGING hypertensive heart: a brief update
Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction
Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced GLYCATION end-products in human myocardium
ALT-946 and aminoguanidine, inhibitors of advanced GLYCATION, improve severe nephropathy in the diabetic transgenic (mREN-2) 27 rat
Lens AGING: effects of crystallins
Causes and consequences of increased arterial stiffness in chronic kidney disease patients
Therapeutic effect of green tea extract on advanced GLYCATION and cross‐linking of collagen in the aorta of streptozotocin diabetic rats
Advanced GLYCATION end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor
Targeting MATRIX remodeling in cardiac hypertrophy and heart failure
Detection of noncarboxymethyllysine and carboxymethyllysine advanced GLYCATION end products (AGE) in serum of diabetic patients
Hyperglycemia and GLYCATION in diabetic complications
Smooth muscle cell pathophysiology and advanced GLYCATION end products (AGEs)
Connective tissue growth factor plays an important role in advanced GLYCATION end product–induced tubular epithelial-to-mesenchymal transition: implications for …
RAGE and its ligands in retinal disease
Advanced GLYCATION end‐products and the kidney
Advanced GLYCATION and advanced lipoxidation: possible role in initiation and progression of diabetic retinopathy
Do advanced GLYCATION end products contribute to the development of long-term diabetic complications?
Evaluation of advanced GLYCATION end-products in diabetic and inherited canine cataracts
GLYCATION
Advanced GLYCATION End Products in Diabetes‐Associated Atherosclerosis and Renal Disease: Interventional Studies
Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy
Can you reduce your AGE?: Strategies to prevent AGE accumulation in diabetes
Basic Science for Clinicians
Chelating activity of advanced GLYCATION end-product inhibitors
Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study
Systolic hypertension in the elderly: arterial wall mechanical properties and the renin–angiotensin–aldosterone system
The metal chelators, trientine and citrate, inhibit the development of cardiac pathology in the Zucker diabetic rat
Inhibition of NADPH oxidase prevents AGE mediated damage in diabetic nephropathy through a protein kinase C-α dependent pathway.
Diabetes increases formation of advanced GLYCATION end products on Sarco (endo) plasmic reticulum Ca2+-ATPase
Pulse pressure and arterial stiffness in type 1 diabetic patients
Advanced GLYCATION end products decrease mesangial cell MMP-7: a role in MATRIX accumulation in diabetic nephropathy?
Advanced GLYCATION End Products in Polycystic Ovarian Syndrome
Glucose, advanced GLYCATION end products, and diabetes complications: what is new and what works
Protection against GLYCATION and similar post-translational modifications of proteins
Pimagedine: a novel therapy for diabetic nephropathy
AGEs and diabetic retinopathy
Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs
Advanced GLYCATION end products in kidney transplant patients: a putative role in the development of chronic renal transplant dysfunction
Renal accumulation and clearance of advanced GLYCATION end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and …
Failure of mineralized collagen fibrils: modeling the role of collagen cross-linking
Medical bioremediation of age-related diseases
Rosiglitazone prevents advanced GLYCATION end products–induced renal toxicity likely through suppression of plasminogen activator inhibitor-1
What is the future of diabetic wound care?
Free radicals and antioxidants in human health: current status and future prospects
Diabetic nephropathy: where hemodynamics meets metabolism
Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus
Diabetes and advanced glycoxidation end products
Molecular determinants of heart failure with normal left ventricular ejection fraction
GLYCATION and tubulointerstitial injury; in vitro and in vivo studies
Central arterial AGING: humans to molecules
Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca2+ regulatory proteins and EXTRACELLULAR MATRIX
RAGE: a multi-ligand receptor unveiling novel insights in health and disease
Non-enzymatic GLYCATION of proteins: from diabetes to cancer
Vascular endothelial dysfunction in diabetic cardiomyopathy: pathogenesis and potential treatment targets
Effects of puerarin on receptor for advanced GLYCATION end products in nephridial tissue of streptozotocin-induced diabetic rats
A tense situation: forcing tumour progression
RAGE: a novel target for drug intervention in diabetic vascular disease
Oxidative stress mediates protein kinase C activation and advanced GLYCATION end product formation in a mesangial cell model of diabetes and high protein diet
Advanced GLYCATION end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways
Advanced GLYCATION–New AGE Focus for Diabetes
Cardiac dysfunction in AGING conscious rats: altered cardiac cytoskeletal proteins as a potential mechanism
Diabetic threesome (hyperglycaemia, renal function and nutrition) and advanced GLYCATION end products: evidence for the multiple-hit agent?
Diabetic vascular disease: it’s all the RAGE
Arterial elasticity in cardiovascular disease: focus on hypertension, metabolic syndrome and diabetes
Regulation of MATRIX synthesis, remodeling and accumulation in glomerulosclerosis
A new perspective on therapeutic inhibition of advanced GLYCATION in diabetic microvascular complications: common downstream endpoints achieved through …
5 Diabetes and Advanced
Advanced GLYCATION end products (AGEs) in diabetes
Vascular stiffening and arterial compliance: implications for systolic blood pressure
Advanced GLYCATION end‐products, anti‐hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction
Ablation of the gene encoding p66 Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE …
Preferential stiffening of central over peripheral arteries in type 2 diabetes
Protein GLYCATION: creation of catalytic sites for free radical generation
Neurodegenerative diseases of the retina and potential for protection and recovery
Age-dependent expression of advanced GLYCATION end product receptor genes in the human heart
Molecular mechanisms of diabetic angiopathy–clues for innovative therapeutic interventions
Diabetic cardiomyopathy
Central arterial AGING and the epidemic of systolic hypertension and atherosclerosis
Use of genetic mouse models in the study of diabetic nephropathy
Soluble Receptor for advanced GLYCATION end products (RAGE) is a prognostic factor for heart failure
GLYCATION, carbonyl stress, EAGLEs, and the vascular complications of diabetes
Pharmacological approaches to the treatment of diabetic complications
Involvement of Maillard reactions in Alzheimer disease
AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced GLYCATION end products, and myocyte resting tension
The Role of Advanced GLYCATION in Diabetic Retinopathy
Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials
Maculoplasty for age-related macular degeneration: reengineering Bruch’s membrane and the human macula
Challenging but essential targets for genuine anti-ageing drugs
Advanced GLYCATION: how are we progressing to combat this web of sugar anomalies in diabetic nephropathy
Factors influencing crosslink formation in muscle tissue
Age effects on vascular smooth muscle: an engineered tissue approach
Arterial stiffness and hypertension: emerging concepts
Collagen in its fibrillar state is protected from GLYCATION
Evaluation of advanced GLYCATION end-products in diabetic and inherited canine cataracts
Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced GLYCATION endproducts
Receptor for advanced GLYCATION end products and the cardiovascular complications of diabetes and beyond: lessons from AGEing
Is human AGING still mysterious enough to be left only to scientists?
AGE-RAGE Interactions: Sticky Sugar Kills
Cardiovascular disease: what’s all the AGE/RAGE about?
The failing diabetic heart: focus on diastolic left ventricular dysfunction
Maillard reaction, mitochondria and oxidative stress: potential role of antioxidants
Molecular mechanisms of diabetic vasculopathy
Inhibitors of advanced GLYCATION end products (AGEs): potential utility for the treatment of cardiovascular disease
Advanced GLYCATION End Products Inhibit Glucose-Stimulated Insulin Secretion through Nitric Oxide-Dependent Inhibition of Cytochrome c Oxidase and Adenosine …
Equal and local-load-sharing micromechanical models for collagens: Quantitative comparisons in response of non-diabetic and diabetic rat tissue
Advanced GLYCATION end-products and diabetic renal disease
AGE-RAGE signalling in endothelial dysfunction and atherosclerosis in diabetes
Growth factors, AGEing, and the diabetes link in Alzheimer’s disease
Mechanisms of vascular AGING: new perspectives
Arterial and cardiac AGING: major shareholders in cardiovascular disease enterprises: Part I: AGING arteries: a “set up” for vascular disease
Oxidative and nitrative stress markers in glaucoma
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
New therapeutic avenues for age-related macular degeneration: targeting Bruch’s membrane
Reactive immunization suppresses advanced GLYCATION and mitigates diabetic nephropathy
Protein cross-linking in the Maillard reaction
Anti-age antibodies and markers of oxidative stress in spontaneously hypertensive rats at different ages
What mechanisms underlie diastolic dysfunction in heart failure?
Disturbance of macro-and microcirculation: relations with pulse pressure and cardiac organ damage
Diabetes and Advanced Glycoxidation End-Products
Polycystic ovary syndrome: the influence of environmental and genetic factors
New potential agents in treating diabetic kidney disease
Receptor for Advanced GLYCATION Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & AGING
New insights into the causes of heart failure
Renal microvascular injury in diabetes: RAGE and redox signaling
Arterial stiffness and systolic hypertension: determinants, assessment, and clinical consequences
The roles of protein GLYCATION, glycoxidation, and advanced GLYCATION end-product formation in diabetes-induced atherosclerosis
Advanced GLYCATION end products (AGEs) and diabetic vascular complications
Alagebrium chloride protects the heart against oxidative stress in AGING rats
Novel therapeutics for diabetic micro-and macrovascular complications
Ageing and vascular ageing
Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease
Inhibition of renin-angiotensin system and advanced GLYCATION end products formation: a promising therapeutic approach targeting on cardiovascular diseases
Advanced GLYCATION end products and nephrotoxicity of high-protein diets
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells—protection by carbonyl scavengers
Oxidative stress in diabetic nephropathy
The sources and the targets of oxidative stress in the etiology of diabetic complications
A mechanical model for collagen fibril load sharing in peripheral nerve of diabetic and nondiabetic rats
Vascular complications in diabetes mellitus: the role of endothelial dysfunction
Arterial stiffness: clinical relevance, measurement and treatment
The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature
GLYCATION of tau protein
Large arteries and the kidney
The RAGE axis and endothelial dysfunction: maladaptive roles in the diabetic vasculature and beyond
MATRIX metalloproteinase-3 genotype contributes to age-related aortic stiffening through modulation of gene and protein expression
Approaches to the development of cosmetic products to counter the effects of skin AGING
Grape seed proanthocyanidins ameliorate diabetic nephropathy via modulation of levels of AGE, RAGE and CTGF
Current concepts in targeted therapies for the pathophysiology of diabetic microvascular complications
Advanced GLYCATION endproduct-induced diabetic complications
Role of advanced GLYCATION end products (AGEs) in diabetic cardiovascular and renal disease
Current perspectives in diastolic dysfunction and diastolic heart failure
Novel approaches to the treatment of progressive renal disease
Methylglyoxal, oxidative stress, and AGING
Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness
Aminoguanidine prevents arterial stiffening and cardiac hypertrophy in streptozotocin‐induced diabetes in rats
15th Golgi lecture: from hyperglycaemia to the dysregulation of vascular remodelling in diabetes
Advanced GLYCATION end products in clinical nephrology
Correlates of aortic stiffness in elderly individuals: a subgroup of the Cardiovascular Health Study
Oxidative stress as a major culprit in kidney disease in diabetes
Diabetic nephropathy: mechanisms of renal disease progression
Modulation of the cellular expression of circulating advanced GLYCATION end-product receptors in type 2 diabetic nephropathy
AGING of the heart and arteries
Advanced GLYCATION end products, rage, and AGING
Targeting the arterial wall, but what is the target?
Mechanical properties of normal and diseased cerebrovascular system
Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation
Advanced GLYCATION end products (AGEs)‐induced expression of TGF‐β1 is suppressed by a protease in the tubule cell line LLC‐PK1
The effect of the microscopic and nanoscale structure on bone fragility
Effect of elastin degradation on carotid wall mechanics as assessed by a constituent-based biomechanical model
Targets for pharmacological modulation of cardiac fibrosis
Agents in development for the treatment of diabetic nephropathy
Mechanisms of Diabetic Complications (Nephropathy) as Related to Perspectives of Treatment
Vascular AGING
AGE and their receptor RAGE in systemic autoimmune diseases: an inflammation propagating factor contributing to accelerated atherosclerosis
Advanced GLYCATION end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase
Validation in awake rats of a tail-cuff method for measuring systolic pressure.
Biochemical process of AGEs formation in complications of hyperglycemia-induced diabetes and its pathological damage effects: A possible target for new drugs
Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering
Diabetic retinopathy: a review
Large artery stiffness predicts ischemic threshold in patients with coronary artery disease
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic …
Future strategies to prevent renal microvascular disease complications in diabetes
Vascular compliance in the cardiometabolic syndrome
Regional arterial stiffness in patients with type 2 diabetes and chronic kidney disease
Quantitative analysis of the effect of diabetes on fibroflast migration
Urinary proteomics in diabetes and CKD
AGE and RAGE inhibitors in the treatment of diabetic retinopathy
Arterial stiffness and hand osteoarthritis: a novel relationship?
Preconditioning with Maillard reaction products improves antioxidant defence leading to increased stress tolerance in cardiac cells
Chronic diabetes increases advanced GLYCATION end products on cardiac ryanodine receptors/calcium-release channels
Molecular mechanisms of diabetic vascular complications
Mechanisms of target organ damage caused by hypertension: therapeutic potential
Left ventricular dysfunction in hypertensive patients with type 2 diabetes mellitus
From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
5. Crucial involvement of advanced GLYCATION end-products in experimental diabetes-associated arterial elastocalcinosis.
The vascular endothelium in diabetes: a practical target fordrug treatment?
Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-α signaling
Hormetic triggers for intervention in AGING, disease and trauma
Skin autofluorescence as a measure of advanced GLYCATION endproduct deposition: a novel risk marker in chronic kidney disease
Strategies for proteomic analysis of non‐enzymatically glycated proteins
Advanced GLYCATION endproducts analysis of glucosamine with reducing sugars, DNA nucleosides and serum proteins
Mechanisms of disease: the oxidative stress theory of diabetic neuropathy
Cell biology of diabetic kidney disease
3, 5-Di-O-caffeoyl-epi-quinic acid from the leaves and stems of Erigeron annuus inhibits protein GLYCATION, aldose reductase, and cataractogenesis
Mitochondrial ageing
Soleus and EDL muscle contractility across the lifespan of female C57BL/6 mice
Treatment of heart failure with normal ejection fraction: an inconvenient truth!
Cardiovascular Changes with AGING
Plasma carboxymethyl‐lysine, an advanced GLYCATION end product, and all‐cause and cardiovascular disease mortality in older community‐dwelling adults
Critical appraisal of the differential effects of antihypertensive agents on arterial stiffness
Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats
Therapeutic Approach on AGE-RAGE Interaction and Its Function in Diabetic Inflammation Process
Molecular and cellular mechanisms by which diabetes mellitus promotes the development of atherosclerosis
Cytotoxicity of advanced GLYCATION endproducts in human micro-and astroglial cell lines depends on the degree of protein GLYCATION
Heart failure with preserved ejection fraction: is there a passage between Scylla and Charybdis?
Tissue-advanced GLYCATION end product concentration in dialysis patients
Influence of lifestyle modification on arterial stiffness and wave reflections
Diabetic patients and kidney protection: an attainable target
9 Cardiovascular Changes with AGING
Emerging therapies for chronic kidney disease: what is their role?
Agents in development for the treatment of diabetic nephropathy
Drug therapy for the cardiac complications of diabetes
The early life origins of vascular ageing and cardiovascular risk: the EVA syndrome
New molecular histopathologic insights into the pathogenesis of age-related macular degeneration
Diastolic dysfunction as a link between hypertension and heart failure
Diabetic cardiomyopathy: mechanisms, diagnosis and treatment
Diabetic kidney disease: emerging mechanism, new therapeutic possibilities
AGEs/RAGE in CKD: irreversible metabolic memory road toward CVD?
Association of arterial stiffness with HbA1c in 1,000 type 2 diabetic patients with or without hypertension
Impaired elastic properties of the aorta in fat-fed, streptozotocin-treated rats
Macrophages and diabetic nephropathy
Emerging drugs for diabetic retinopathy
Pathophysiology and treatment of diabetic peripheral neuropathy: the case for diabetic neurovascular function as an essential component
Type 2 diabetes—implications for macrovascular mechanics and disease
Pulse pressure and arterial stiffness in rats: comparison with humans
Preservation of pressure-induced cutaneous vasodilation by limiting oxidative stress in short-term diabetic mice
Diabetic cardiomyopathy: the search for a unifying hypothesis
Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced GLYCATION end products in lipofuscin of human retinal pigment epithelium
Characterizing the advanced GLYCATION endproducts formation of proteins and nucleotides by methylglyoxal and glyoxal
Greater age-related reductions in central arterial compliance in resistance-trained men
Future Therapies in Diastolic Heart Failure
Inhibition of protein GLYCATION by polyphenolic extracts of culinary herbs and spices
Blood pressure, large arteries and atherosclerosis
Obesity and vascular compliance
Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo
Coupled systolic-ventricular and vascular stiffening with age: implications for pressure regulation and cardiac reserve in the elderly
Effects of collagen dysregulation on structure and mechanics of normal and post-infarction myocardium
EXTRACELLULAR protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications
Arterial stiffness and coronary ischemic disease
Structural remodeling in the limb circulation: impact of obesity and diabetes
Arterial stiffness and kidney function
Mechanical factors in arterial AGING: a clinical perspective
The future of AGING therapies
Biocompatibility of icodextrin
Update on the treatment of diabetic retinopathy
Inhibition of protein kinase C in diabetic nephropathy—where do we stand?
Animal models of arterial stiffness
Impact of age and hyperglycemia on the mechanical behavior of intact human coronary arteries: an ex vivo intravascular ultrasound study
Advanced GLYCATION end‐products in sickle cell anaemia
Oxidative stress and uremia
Recent advances in pharmacotherapy for diabetic nephropathy: current perspectives and future directions
Heart failure in the elderly: advances and challenges
The diabetic myocardium
Aldosterone receptor inhibition alters the viscoelastic biomechanical behavior of the aortic wall
… GLYCATION end products levels are related to ischaemic aetiology and extent of coronary disease in chronic heart failure patients, independent of advanced GLYCATION …
Mechanisms involved in the genesis of diabetic nephropathy
Effects of low‐level light therapy on hepatic antioxidant defense in acute and chronic diabetic rats
Diastolic disturbances in diabetes mellitus
Plasticity of kidney cells: role in kidney remodeling and scarring
Modification of the Glycemic Status on Aortic Distensibility by Age in the Multi-Ethnic Study of Atherosclerosis
Pentosidine accumulates in the AGING vitreous body: a gender effect
Synergistic attenuation of myocardial fibrosis in spontaneously hypertensive rats by joint treatment with benazepril and candesartan
Cellular therapy using microglial cells
Introduction of hyperglycemia and dyslipidemia in the pathogenesis of diabetic vascular complications
Interactions between angiotensin ll and atrial natriuretic peptide in renomedullary interstitial cells: the role of neutral endopeptidase
Emerging drugs for acute and chronic heart failure: current and future developments
Experimental models for the study of the cellular and molecular pathophysiology of Peyronie’s disease
Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment
… anti-glucose oxidase antibodies or the F (ab)′ 2/F (ab)′ fragments derived therefrom protects both the enzyme and antibody/antibody fragments against GLYCATION
Skin AGING handbook: an integrated approach to biochemistry and product development
Role of methylglyoxal in the pathogenesis of hypertension
Mechanisms, significance and treatment of vascular dysfunction in type 2 diabetes mellitus
The metabolic syndrome in elderly individuals is associated with greater muscular, but not elastic arterial stiffness, independent of low-grade inflammation …
Medical treatment of diabetic retinopathy
Future strategies for the treatment of diastolic heart failure
RAGE and soluble RAGE: potential therapeutic targets for cardiovascular diseases
Disruptions and detours in the myocardial MATRIX highway and heart failure
Study on the nonenzymatic GLYCATION of nucleosides/nucleotides and proteins with sugars: An in vitro investigation of advanced GLYCATION endproducts (AGEs) …
Structural emphysema does not correlate with lung compliance: lessons from the mouse smoking model
Reversing chronic remodeling in heart failure
Connective tissue growth factor and cardiac fibrosis
[11] Advanced GLYCATION end products: Detection and reversal
Arterial Stiffness and Coronary Ischemic
Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity
Reducing the burden of diabetic vascular complications
New therapeutic agents for diabetic kidney disease
Discovery of rifampicin as a new anti-glycating compound by MATRIX-assisted laser desorption/ionization mass spectrometry-based insulin GLYCATION assay
Intervening in atherogenesis: lessons from diabetes
Large artery stiffness and antihypertensive agents
Effects of blood pressure lowering and metabolic control on systolic left ventricular function in Type II diabetes mellitus
Pathogenesis and pathophysiology of diabetic nephropathy
Cardiac overexpression of antioxidant catalase attenuates AGING-induced cardiomyocyte relaxation dysfunction
Biochemistry of tropoelastin
Advanced GLYCATION end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation …
The heart, macrocirculation and microcirculation in hypertension: a unifying hypothesis
Using myocardial imAGING to identify and manage subclinical heart disease in diabetes mellitus and obesity
ADVANCED GLYCATION END PRODUCTS AND THEIR RECEPTOR RAGE IN SYSTEMIC AUTOIMMUNE DISEASES
Post-translational modifications of proteins: implications for AGING, antigen recognition, and autoimmunity
Diabetes complications
Vitamin B1 blocks damage caused by hyperglycemia
Arterial Stiffness and Hypertension: A Review of Mechanism and Clinical Relevance
OCT activity and GLYCATION damage in rat liver mitochondria
AGING and the Frontier Ahead
The role of arterial stiffness in stratifying the overall cardiovascular risk
Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy
Clinical applications of arterial stiffness: therapeutics and pharmacology
Pacing and Diastolic Heart Failure
Low adipocyte IRS-1 protein expression is associated with an increased arterial stiffness in non-diabetic males
Protein carbonylation, cellular dysfunction, and disease progression
Clinical trials update from the European Society of Cardiology Heart Failure Meeting 2010: TRIDENT 1, BENEFICIAL, CUPID, RFA‐HF, MUSIC, DUEL, handheld BNP …
The role of protein kinase C activation and the vascular complications of diabetes
Atherosclerosis, arterial stiffness and antihypertensive drug therapy
Developing and characterization of bioadsorbent for extracorporeal blood purification
The skin
Mechanisms of kidney fibrosis and the role of antifibrotic therapies
Pulse wave velocity as a marker of arteriosclerosis and its comorbidities in Chinese patients
New horizons in the management of cardiovascular disease
Inhibition of protein GLYCATION by extracts of culinary herbs and spices
Hypertension and diabetes
Heart failure and nephropathy: catastrophic and interrelated complications of diabetes
Role of inflammation in diabetic nephropathy
The role of renin–angiotensin–aldosterone system inhibition in chronic kidney disease
EXTRACELLULAR remodeling in heart failure–potential use of MMP inhibitors
Nutrition, Diet, and Supplements for Peak Physical & Mental Performance
Poly (adenosine 5′-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy
The pulsatile component of blood pressure–Its role in the pathogenesis of atherosclerosis
A microstructural hyperelastic model of pulmonary arteries under normo-and hypertensive conditions
Pyridoxal phosphate prevents progression of diabetic nephropathy
Alterations in circulatory function
Aortic correlates of clinical markers of large artery structure and function. Effects of AGING and hypertension
Does angiotensin receptor blockade improve outcomes in patients with heart failure and preserved ejection fraction? Results of the I-PRESERVE study
Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis _ state of the art
AGING of the Vasculature and Related Systems
Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function
Hypertension and cardiovascular disease
Molecular and Cellular Phenotypes of Cardiovascular AGING
Diabetic cardiomyopathy
Linking diabetes and atherosclerosis
Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies
Cardiovascular complications in diabetes mellitus
Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets
Arterial stiffness in chronic inflammatory diseases
Diabetic cardiomyopathy: signaling defects and therapeutic approaches
Cardiovascular biomarkers in CKD: pathophysiology and implications for clinical management of cardiac disease
Covalent binding antibodies suppress advanced GLYCATION: on the innate tier of adaptive immunity
Large animal models for diastolic dysfunction and diastolic heart failure—a review of the literature
Vascular Endothelial Growth Factor as a Determinant of Diabetic Nephropathy
Type 2 diabetes, related conditions, in relation and dementia: an opportunity for prevention?
Apoptosis in patients with dilated cardiomyopathy and diabetes: a feature of diabetic cardiomyopathy?
High-density lipoprotein at the interface of type 2 diabetes mellitus and cardiovascular disorders
Studies on protein GLYCATION
Diabetes and the skin: an update for dermatologists
Chronic heart failure in the elderly: a current medical problem
Cardiovascular risk factors in type 2 diabetes: the role of hyperglycaemia
Cellular Noise and The AGING Process
Plasma protein advanced GLYCATION end products, carboxymethyl cysteine, and carboxyethyl cysteine, are elevated and related to nephropathy in patients with …
Biochemical and molecular mechanisms of diabetic retinopathy
Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria
Assessment of protein glycoxidation in ventricular tissues
Arterial stiffness and the systolic hypertension syndrome
Cardiac metabolism in diabetes mellitus
Differential regulation of collagen types I and III expression in cardiac fibroblasts by AGEs through TRB3/MAPK signaling pathway
Pioglitazone improves aortic wall elasticity in a rat model of elastocalcinotic arteriosclerosis
Reactivity-based drug discovery using vitamin B6-derived pharmacophores
Covalent binding antibodies suppress advanced GLYCATION: on the innate tier of adaptive
Is AGE accumulation a therapeutic target for diabetic complications?
Role of increased aortic stiffness in the pathogenesis of heart failure
Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering
Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers
Development and post-pilot modification of a questionnaire for assessing dietary AGE intake in Australian children with and without type 1 diabetes mellitus
Metabolism, cell surface organization, and disease
The association of heart failure with insulin resistance and the development of type 2 diabetes
Methylglyoxal, diabetes mellitus and diabetic complications
Aortic correlates of clinical markers of large artery structure and function. Effects of AGING and hypertension
Hypertension and Cardiovascular
Interventions in AGING and Age-Related Diseases: The Present and the Future
Diabetes mellitus-associated atherosclerosis
Development of an experimental system to determine the contribution of titin and collagen to passive stiffness of myocardium
Diabetic cardiomyopathy
Antioxidants reverse age-related collateral growth impairment
Redox changes precede the occurrence of oxidative stress in eyes and aorta, but not in kidneys of diabetic rats
Pulse pressure, arterial stiffness, and drug treatment of hypertension
PLC/CAMK IV–NF-κB involved in the receptor for advanced GLYCATION end products mediated signaling pathway in human endothelial cells
Intake of advanced GLYCATION endproducts: Role in the development of diabetic complications
Pulse pressure—a review of mechanisms and clinical relevance
RAGE in diabetic nephropathy
Age-and gender-related oxidative status determined in healthy subjects by means of OXY-SCORE, a potential new comprehensive index
Walking may be related to less vascular stiffness in the Activity Counseling Trial (ACT)
Pyridoxamine inhibits chemical modification of proteins by lipid peroxidation reactions, in vitro: Mechanism of action of pyridoxamine
Characteristics of arterial stiffness in very low birth weight premature infants
Oxidative stress and functional deficit in diabetic cardiomyopathy
Central blood pressure and hypertension: role in cardiovascular risk assessment
Altered Glucose Transport and Its Metabolic Effects in Glomerular Cells
Angiotensin II and the cardiac complications of diabetes mellitus
The role of scavenging antioxidants and the transcription factor NRF2 in protection against advanced GLYCATION end products in a neuronal-derived cell line
Chronic estradiol treatment attenuates stiffening, glycoxidation, and permeability in rat carotid arteries
Specific aspects of high blood pressure in the elderly
Ascorbic acid selectively improves large elastic artery compliance in postmenopausal women
Altered Glucose Transport and Its Metabolic Effects in Glomerular Cells
Response to Comment on: Thallas-Bonke et al.(2008) Inhibition of NADPH Oxidase Prevents Advanced GLYCATION End Product–Mediated Damage in Diabetic …
Therapeutic interventions and oxidative stress in diabetes
AGING and arterial structure-function relations
Fifth Pivotal Research in Cardiology in the Elderly (PRICE‐V) Symposium: Preventive Cardiology in the Elderly—Executive Summary. Part I: Morning Session
Physiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscle
Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure
Early predictors of cardiac decompensation in experimental volume overload
Reduced acute vascular injury and atherosclerosis in hyperlipidemic mice transgenic for lysozyme
CCN genes and the kidney
Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study
Hypertension, systolic blood pressure, and large arteries
Heart failure with normal ejection fraction: consideration of mechanisms other than diastolic dysfunction
Arterial stiffness: a potential therapeutic target to reduce cardiovascular mortality
Role of exercise and metabolism in heart failure with normal ejection fraction
Pathogenic factors in vascular dementia and Alzheimer’s disease
MATRIX metalloproteinase in left ventricular remodeling and heart failure
The RAGE Axis
Diabetic neuropathy: mechanisms to management
Hepatocyte susceptibility to glyoxal is dependent on cell thiamin content
Animal models of diabetes mellitus: relevance to vascular complications
Emerging drugs for diabetic nephropathy
Evolving insights into the pathophysiology of heart failure with preserved ejection fraction
Arterial stiffness and stroke in hypertension
Recapitulation of embryological programmes in renal fibrosis–the importance of epithelial cell plasticity and developmental genes
Constituents of the flowers of Platycodon grandiflorum with inhibitory activity on advanced GLYCATION end products and rat lens aldose reductase in vitro
8th EASD/JDRF OXFORD WORKSHOP
Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 …
CCN GENESAND THE KIDNEY
Inflammatory mediators in diabetic retinopathy
Drug discovery for heart failure: a new era or the end of the pipeline?
Proinsulin C‐peptide abrogates type‐1 diabetes‐induced increase of renal endothelial nitric oxide synthase in rats
Examination of advanced GLYCATION end-products in children with type 1 diabetes
Comprehensive nanorobotic control of human morbidity and AGING
Effects of blocking the renin-angiotensin system on expression and translocation of protein kinase C isoforms in the kidney of diabetic rats
Pathophysiologic Aspects of Myocardial Relaxation and End-Diastolic Stiffness of Cardiac Ventricles
Integrins as unique receptors for vascular control
Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways
Why don’t fistulas mature?
Leg flow-mediated arterial dilation in elderly patients with heart failure and normal left ventricular ejection fraction
Diastolic dysfunction in diabetic normotensive patients, regardless of the presence of microangiopathy
GM MTS S00S S GMMM MMMMMMMS
15 Large artery stiffness and
URINARY PROTEOMICS IN DIABETES AND CHRONIC RENAL DISEASE
The effects of diabetes and aminoguanidine treatment on endothelial function in a primate model of type 1 diabetes
IDEPARTMENT OF BIOCHEMISTRY AND 2DEPARTMENT OF UROLOGY, KUMAMOTO UNIVERSITY SCHOOL OF MEDICINE, HONJO 2-2-1, KUMAMOTO 860 …
The central arterial burden of the metabolic syndrome is similar in men and women: the SardiNIA Study
Diabetic microangiopathy in ischemic limb is a disease of disturbance of the platelet-derived growth factor-BB/protein kinase C axis but not of impaired expression of …
Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine …
Cross-talk between cardiac muscle and coronary vasculature
Natural compounds with potential antioxidant activity; in vitro study in a model of protein glycoxidation
Arterial stiffness and cardiovascular risk factors
Heart failure with normal ejection fraction
Altered multiaxial mechanical properties of the porcine anterior lens capsule cultured in high glucose
Insulin resistance syndrome: interaction with coagulation and fibrinolysis
Redox control of renal function and hypertension
Nonenzymatic antioxidative and antiglycative effects of oleanolic acid and ursolic acid
Heart failure with normal left ventricular ejection fraction: what is the evidence?
AGING and the Cardiovascular System
The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007
Investigational drugs for diabetic nephropathy
Influence of alpha-lipoic acid on streptozotocin induced diabetic cardiomyopathy in adult male albino rats: A biochemical and microscopical study
Novel therapeutic targets for diabetic nephropathy
The gero-inflammatory manifold
Association of plasma pentosidine concentrations with renal function in kidney graft recipients
Structure-function studies of amadoriase enzymes from Aspergillus sp., relevance for treatment of diabetic complications
Lipoproteins, glycoxidation and diabetic angiopathy
The Impact of Diabetic Renal Disease
28 Diabetes, lipids and other cardiovascular risk factors
Will new antihypertensive drugs emerge? Part 1
Cardiomyopathy and heart failure in AGING
Risk factors preceding type 2 diabetes and cardiomyopathy
Arterial Stiffness is Related to Oxidative Stress, Inflammation, and Calcium-phosphate Metabolism in Haemodialysis Patients
The AGING of the heart and blood vessels: a consideration of anatomy and physiology in the era of computed tomography, magnetic resonance imAGING, and positron …
The role of GLYCATION and glycoxidation of low-density lipoproteins in foam cell formation.
Mechanisms linking diabetes mellitus to the development of atherosclerosis: a role for endoplasmic reticulum stress and glycogen synthase kinase-3
Development of an oral fluid assay for the detection of uncontrolled diabetics using glycated albumin as a marker
Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model
Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities
Sweet heart–contributions of metabolism in the development of heart failure in diabetes mellitus
Murine models to investigate the influence of diabetic metabolism on the development of atherosclerosis and restenosis
Recent advances in diabetic nephropathy
Novel pharmacological treatments for heart failure
Current perspectives on cardiac function in patients with diastolic heart failure
Agents that modulate peritoneal membrane structure and function
Laboratory forum: experimental models of Peyronie’s disease. Implications for new therapies
Renal effects of C-peptide in experimental type-1 diabetes mellitus
Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and MATRIX
A mechanistic strain energy function and experimental results for the human annulus fibrosus
Diastolic dysfunction and heart failure with preserved ejection fraction: rationale for RAAS antagonist/CCB combination therapy
Evolving pandemic diabetic nephropathy
Vascular pharmacology: opportunities for intervention
Clinical and therapeutic aspects of diabetic nephropathy
Basic Mechanisms Mediating Cardiomyopathy and Heart Failure in AGING
Current therapies and emerging targets for the treatment of diabetes
Subclinical left ventricular dysfunction in hypertension and diabetes assessed by tissue Doppler imAGING
Structure-function relationships in soft tissue mechanics: Examining how the micro-scale architecture of biochemical constituents effects health
Ultrasonic delineation of aortic microstructure: the relative contribution of elastin and collagen to aortic elasticity
Oxidative Stress in Diabetes-A Key Therapeutic Agent
Ambulatory monitoring of the cardiovascular system: the role of pulse wave velocity
The impact of the diabetic state on gingival tissues: The role of tetracyclines in disease management
The relationship between the continuum of elevated adiposity, hyperinsulinemia, and type 2 diabetes and late-onset Alzheimer’s disease: An epidemiological …
Mechanisms in protein O-glycan biosynthesis and clinical and molecular aspects of protein O-glycan biosynthesis defects: a review
Targeting the protein kinase C family in the diabetic kidney: lessons from analysis of mutant mice
Progress towards medical bioremediation by enzymatic transformation of 7-ketocholesterol and the pyridinium bisretinoid A2E
Pathogenesis of renal microvascular complications in diabetes mellitus
Preservation of protein in marine systems: Hydrophobic and other noncovalent associations as major stabilizing forces
Reduced wall compliance suppresses Akt-dependent apoptosis protection stimulated by pulse perfusion
Chasing the wave. Unfashionable but important new concepts in arterial wave travel
A mechanical model of porcine vascular tissues-Part II: Stress–strain and mechanical properties of juvenile porcine blood vessels
KIOM-79 prevents S100b-induced TGF-β1 and fibronectin expression in mouse mesangial cells
11 Diagnosis and assessment of non-pulmonary arterial hypertension masquerading as idiopathic pulmonary arterial
Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy
Preventive strategies for diabetic nephropathy
Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of MATRIX metalloproteinases
Micronutrients that decrease endogenous toxins, a strategy for disease prevention
Endogenous secretory RAGE as a novel biomarker for metabolic syndrome and cardiovascular diseases
Clinical studies on coronary revascularization in patients with type 2 diabetes
The diabetic, hypertensive heart: epidemiology and mechanisms of a very high-risk situation
Novel insights in the treatment of diabetic nephropathy
Rationale for a metabolic approach in diabetic coronary patients
Atrial remodeling and atrial fibrillation: mechanistic interactions and clinical implications
Nephrin in diabetes and in diabetes-related conditions: Emphasis on urinary proteins immunoreactive with nephrin antibodies
Arterial stiffness and subclinical atherosclerosis in elderly participants from the Cardiovascular Health Study
Heart failure with normal left ventricular ejection fraction
Hypertension and Diabetes: A Dangerous Liaison
Omega-3 fatty acid rich diet prevents diabetic renal disease
The effect of age and ovarian hormones on skeletal muscle contractility and myosin in female mice
Methylglyoxal-induced increase in peroxynitrite and inflammation related to diabetes
The effects of strength training on arterial structure and function in middle-aged and older adults
Acute effects of interferon-alpha administration on testosterone concentrations in healthy men
Biogenesis and metabolism of Alzheimer’s disease Aβ amyloid peptides
LIVIU KLEIN, MD, MS ROBERT O. BONOW, MD
Ageing: biology and nutrition
Characterization of the Alzheimer´ s disease-associated clac protein
Retinal blood flow and vascular reactivity in diabetic retinopathy
Impact of Oxidative Stress on Diabetes Mellitus and Inflammatory Bowel Diseases
Applied healthspan engineering
Mechanical and structural changes in diabetic rat peripheral nerve collagens
Calcified splenic artery
Bibliography Current World Literature Vol 19 No 4 July 2004
Fisiopatología de la nefropatía diabética
Diabetic nephropathy: diagnosis, prevention, and treatment
Effect of telmisartan on expression of protein kinase C‐α in kidneys of diabetic mice1
Clinical presentation, treatment, and prognosis of heart failure in diabetes
Candidate Genes for Late Diabetic Complications
Diabetic vascular disease: from endothelial dysfunction to atherosclerosis
Rôle du système rénine-angiotensine intrarénal dans l’hypertension et les dommages rénaux chez les souris transgéniques diabétiques
The effect of blood glucose on the vasculature in young patients with type 1 diabetes
Myocardial infarction, heart failure and sympathetic nervous system activity: new pharmacological approaches that affect neurohumoral activation
Beta amyloid peptide: from different aggregation forms to the activation of different biochemical pathways
Relationship between Insulin Resistance and Left Ventricular Diastolic Dysfunction
Uremic toxins
Protective effect of calcium dobesilate against inflammation and oxidative/nitrosative stress in the retina of a diabetic rat model
Mechanisms underlying changes in microvascular blood flow in a diabetic rat model: relevance to tissue repair
Textbook of pathology
Effects of AGING and exercise training on structural and vasoconstrictor properties of skeletal muscle arterioles
Cardiovascular dysfunction in Zucker obese and Zucker diabetic fatty rats: role of hydronephrosis
Biomechanics of the Lens Capsule from Native to After Cataract Surgery
The structural basis of arterial stiffness and its relationship to cardiovascular outcome
Angiotensin II contributes to arterial compliance in congestive heart failure
Enhancement of fruit shelf life by suppressing N-glycan processing enzymes
Age-related changes in vascular structure and function Determinants and cardiovascular risk
Renal immunology and pathology
The amyloid‐β peptide and its role in Alzheimer’s disease
Current Therapies and Emerging Targets for the Treatment of Diabetes
Arterial stiffness, functional decline and mortality risk in older adults
Substrate Metabolism in the Diabetic Heart: Relationship to the Observed Cardiac Dysfunction and the Significance of Putative Mechanisms in the Control of …
Detection of Deoxyribonucleic Acid Damage Induced by Metal Ion Interactions and Repair of Metal Ion Deoxyribonucleic Acid Cross-links
To what extent can coronary calcification and arterial stiffness be influenced by the nephrologist?
Ultrastructural Dynamics of Human Reproduction, from Ovulation to Fertilization and Early Embryo Development1
Hormones, autacoids, neurotransmitters and growth factors
The Influence of Exercise on Inflammation and IGF-1 Signaling in Diabetes
10 Vitamin B6
Comprehensive assessment and pulsed electromagnetic therapy for diabetic peripheral neuropathy
Emerging drugs for renal failure
Heart failure: A combined medical and surgical approach
Michael R. Graham, Julien S. Baker
The Effects of Weight Gain and Atorvastatin Treatment on Arterial Stiffness
Causes and diagnosis of Alzheimer’s disease: a proteomics approach
Revisiting methods for assessing and comparing left ventricular diastolic stiffness: impact of relaxation, external forces, hypertrophy, and comparators
Agarwal MR, Feldon SE, Nguyen V. Clinical Features of Graves’ Ophthalmopathy in a Latino Incidence Cohort. E-337. Agarwal N, Patel N, Cai ZY, Covey D, Simpkins …
Rapid Review Biochemistry E-Book
Molecular genetics
Emerging affinity-based techniques in proteomics
Mineral metabolism
Insights into structure and dynamics of MATRIX metalloproteinase-9
Viscoelastic behavior of small intestine in streptozotocin-induced diabetic rats
Anthraquinones inhibit tau aggregation and dissolve Alzheimer’s paired helical filaments in vitro and in cells
The Bimodal Features of Butyrylcholinesterase in Cholinergic Neurotransmission and Amyloid Suppression
4.5 Ab POLYMERIZATION REDUCTION
Pharmacotherapeutic targets in Alzheimer’s disease
Pharmacological treatment of Alzheimer disease: from psychotropic drugs and cholinesterase inhibitors to pharmacogenomics
Washington State University, Pullman, WA 99164-6340
The effects of acute muscle damage and autoimmune disease on vascular function: The potential role of inflammation
WSLB01–Macrophages, Neutrophils and other Myeloid Cells
Diabetes mellitus: pathophysiology, etiologies, complications, management, and laboratory evaluation: special topics in diagnostic testing
Misfolding of the prion protein: linking biophysical and biological approaches
Beta-amyloid/plasma lipoprotein interactions: Implications got vascular damage
Interaction of viruses with human joint material
Pulse transit time and the pulse wave contour as measured by photoplethysmography: the effect of drugs and exercise
Influence of glycemic control on the development of diabetic cardiovascular and kidney disease
The role of Rab GTPases in cell wall metabolism
Studies of vascular function in patients with heart failure and either preserved or reduced left ventricular systolic function
In vitro modelling of neurodegeneration and neuroprotection specific for Alzheimer’s disease in cell cultures
Evaluation of the ability of antioxidants to counteract lipid oxidation: Existing methods, new trends and challenges
The development and use of a new animal model for inflammatory bowel disease
THE INVESTIGATION, DEVELOPMENT
Biogenesis of tartrate-resistant acid phosphatase isoforms 5a and 5b in cell and animal models
Structural elements that regulate interactions between the EXTRACELLULAR and transmembrane domains of human nucleoside triphosphate diphosphohydrolase …
Synthesis and biological activity of gramicidin S analogues containing constrained phenylalanines
Protein aggregation: A perspective from amyloid and inclusion-body formation
Strength and compassion in kidney failure: writings of Mildred (Barry) Friedman, professional kidney patient
Growing bone
Prediction of factors determining changes in stability in protein mutants
Biomechanics, biochemistry, and molecular biology of a molluscan scleroprotein elastomer: whelk egg capsules
Engineering Cell Function by RNA Interference
Survey of the year 2003 commercial optical biosensor literature
The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene family
Molecular aspects of ripening-and stress-related protein metabolism in higher plants
Food proteins: properties and characterization
Pathogenic interactions between the amyloid β-protein and cerebrovascular smooth muscle cells
BIOT 1 Investigation of the use of FACS in cell line development
Diffusion of protease inhibitors in the muscle cell
Molecular cloning and characterization of the beta-subunit of tomato fruit polygalacturonase isoenzyme 1
Characterization of growth hormone induced signal transduction intermediates in liver, kidney, and fat of “Dwarf” and “Giant” mice
The phagotrophic origin of eukaryotes and phylogenetic classification of Protozoa.
Targeted siRNA carrier systems for the treatment of acute myeloid leukaemia (AML)
… G2, to Achieve High Level Active Enzyme Expression at the Plasma Membrane of Tumour Cells, Facilitating Localised Extra-Cellular Prodrug Activation and …
Industrial fermentation: principles, processes, and products
The secreted aspartic proteinases of Candida albicans: a thesis submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Institute …
Single chain antibodies against the 37 kDa/67 kDa laminin receptor as tools for prion diseases therapy
Peptides for Youth: The Proceedings of the 20th American Peptide Symposium
COLLAGEN FIBRIL FORMATION IN THE PRESENCE OF DEXAMETHASONE PHOSPHATE AND SODIUM DODECYL SULFATE (MORPHOLOGY)
Biotechnology for New Zealand engineers: A review.
HIF-1α modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms
The Molecular Basis of Familial Danish Dementia
Interaction studies between biocompatible polymers and amyloid-B peptides
Intracellular pathways involved in formation and degradation of prions
Vertebrate membrane proteins: structure, function, and insights from biophysical approaches
Natural protein motifs and their use in design
Importance of methionine 35 in free radical-associated mechanisms of Alzheimer’s amyloid beta-peptide neurotoxicity, and experimental rationale for the use …
Microarrays and mass spectrometry-the future of proteomics
Abstracts, Division of Biological Chemistry, 219th National Meeting of the American Chemical Society, March 26− 30, 2000
Aggregation of therapeutic proteins
The design, synthesis and evaluation of affinity ligands for prion proteins
Aptamers for proteomics
Analysis of the Molecular Basis of the Conversion and Aggregation of Prion Proteins induced by Oxidative Stress
The 37kDa/67kDa laminin receptor as a therapeutic target in prion diseases: potency of antisense LRP RNA, siRNAs specific for LRP mRNA and a LRP decoy mutant
CHARACTERIZATION OF A THIRD FORM OF THE MAJOR ERYTHROCYTE MEMBRANE GLYCOPROTEIN IN SODIUM DODECYL SULFATE.
Anti-viral immunity in Anopheles gambiae mosquitoes
Development of ss DNA aptamers for c-Myc: Max by SELEX (Systematic Evolution of Ligands by Exponential Enrichment)
Hydrophobic Interaction Chromatography of Carbohydrates and Glycoconjugates
Bioactivity and structure of biophenols as mediators of chronic diseases
Engineering the bioelectronic interface: applications to analyte biosensing and protein detection
Peptide Design Considerations
1. Teaching Evolution through Evo-Devo. Scott F. Gilbert. Swarth
Structure-function analysis of Phytophthora parasitica elicitins
Studies of the refolding processes of recombinant growth hormones
12 Sugar and abscisic acid regulation of germination and transition to seedling growth
Maternal and placental adaptations to hypoxia
Cloning and expression analysis of tomato abscission cell wall hydrolases
Interaction of deamidated soluble wheat protein (SWP) with other food proteins and metals
DNase 1 hypersensitive sites in rabbit cytochrome P-450IIC subfamily genes and binding of liver nuclear proteins
Industrial fermentation: principles, processes, and products
Evaluation of some food processing by-products as sources for natural antioxidants
The Role of Glycoprotein H in Varicella-Zoster Virus Pathogenesis
Evaluation of some food processing by-products as sources for natural antioxidants Untersuchung und Charakterisierung von Nebenprodukten der …
Synthesis of irisquinone and analogues: Evaluation of their anti-cancer properties
The Effects of Cholesterol on the Structure and Function of
Characterization of RNA aptamers that bind to HIV-1 gp120
Intracellular pathways in prion peptide trafficking
Colour changes during chilling of tomato (Lycopersicon esculentum Mill.) fruit, surface topology of injury and some physiological changes
The role of collagen crosslinks in ageing and diabetes-the good, the bad, and the ugly
Potential clinical utility of advanced GLYCATION end product cross-link BREAKERs in age-and diabetes-associated disorders
Protein GLYCATION during AGING and in cardiovascular disease
Role of advanced GLYCATION end products in cardiovascular disease
Attenuating effects of Ganoderma lucidum polysaccharides on myocardial collagen cross-linking relates to advanced GLYCATION end product and antioxidant enzymes …
The impact of AGING on cardiac EXTRACELLULAR MATRIX
Advanced GLYCATION end products mediated cellular and molecular events in the pathology of diabetic nephropathy
An update on advanced GLYCATION endproducts and atherosclerosis
Emerging role of advanced GLYCATION-end products (AGEs) in the pathobiology of eye diseases
Advanced GLYCATION end products: key players in skin AGING?
Advanced GLYCATION end products: role in pathology of diabetic cardiomyopathy
Advanced GLYCATION end products: association with the pathogenesis of diseases and the current therapeutic advances
Cardiac fibroblast-dependent EXTRACELLULAR MATRIX accumulation is associated with diastolic stiffness in type 2 diabetes
Molecular basis of arterial stiffening: role of GLYCATION–a mini-review
Involvement of advanced GLYCATION end products in the pathogenesis of diabetic retinopathy
Advanced GLYCATION end product associated skin autofluorescence: a mirror of vascular function?
Exercise training initiated in late middle age attenuates cardiac fibrosis and advanced GLYCATION end-product accumulation in senescent rats
The role of nonenzymatic GLYCATION and carbonyls in collagen cross-linking for the treatment of keratoconus
Proinflammation: the key to arterial AGING
Molecular mechanisms of AGE/RAGE-mediated fibrosis in the diabetic heart
A fast and mild decellularization protocol for obtaining EXTRACELLULAR MATRIX
Age-related vascular stiffening: causes and consequences
Therapeutic interventions against accumulation of advanced GLYCATION end products (AGEs)
Potential of collagen cross-linking therapies to mediate tendon mechanical properties
Molecular effects of advanced GLYCATION end products on cell signalling pathways, ageing and pathophysiology
Advanced GLYCATION end-products: a common pathway in diabetes and age-related erectile dysfunction
Large elastic artery stiffness with AGING: novel translational mechanisms and interventions
Advanced GLYCATION end products and diabetic complications
Effects of alagebrium, an advanced GLYCATION endproduct BREAKER, on exercise tolerance and cardiac function in patients with chronic heart failure
Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration
Pharmacological control of receptor of advanced GLYCATION end-products and its biological effects in psoriasis
GLYCATION stress and photo-AGING in skin
Advanced GLYCATION end products (AGEs) and cardiovascular dysfunction: focus on high molecular weight AGEs
Mechanistic targeting of advanced GLYCATION end-products in age-related diseases
Advanced GLYCATION end products
Naturally occurring inhibitors against the formation of advanced GLYCATION end-products
Advanced GLYCATION end products: a link between periodontitis and diabetes mellitus?
Targeting EXTRACELLULAR MATRIX stiffness to attenuate disease: From molecular mechanisms to clinical trials
AGING and ocular tissue stiffness in glaucoma
Implication of advanced GLYCATION end products (Ages) and their receptor (Rage) on myocardial contractile and mitochondrial functions
The Effect of Advanced GLYCATION End Products (AGE) BREAKER, Alagebrium on the Cardiac Structural and Functional Change in Type I Diabetic Rat Model
Current therapeutic interventions in the GLYCATION pathway: evidence from clinical studies
Significance of advanced GLYCATION end-products (AGE) and the receptor for AGE (RAGE) in diabetic nephropathy
AGING and cardiac fibrosis
Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus
Effect of GLYCATION inhibitors on AGING and age-related diseases
The AGE-RAGE axis: implications for age-associated arterial diseases
Current perspectives on the health risks associated with the consumption of advanced GLYCATION end products: recommendations for dietary management
Soft-tissue wound healing by anti-advanced GLYCATION end-products agents
Relationship of advanced GLYCATION end products with cardiovascular disease in menopausal women
Advanced GLYCATION End-products (AGEs): an emerging concern for processed food industries
Chelation: a fundamental mechanism of action of AGE inhibitors, AGE BREAKERs, and other inhibitors of diabetes complications
Natural products as anti-GLYCATION agents: possible therapeutic potential for diabetic complications
Pharmacologic approaches against advanced GLYCATION end products (AGEs) in diabetic cardiovascular disease
Do advanced GLYCATION end products and its receptor play a role in pathophysiology of hypertension?
Advanced GLYCATION Endproducts,(AGEs): Formation, Complication and Pharmacological Evaluation to Its Inhibition
Tissue taurine depletion induces profibrotic pattern of gene expression and causes AGING-related cardiac fibrosis in heart in mice
GLYCATION: Implication in perceived age and dermatology
The accumulation of the glycoxidation product Nε-carboxymethyllysine in Cardiac Tissues with age, diabetes mellitus and coronary heart disease
Phytochemicals against advanced GLYCATION end products (AGEs) and the receptor system
Natural inhibitors of advanced GLYCATION end‐products
The effects of advanced GLYCATION end products (AGEs) on dermal wound healing and scar formation: a systematic review
Cross-linking versus RAGE: How do high molecular weight advanced GLYCATION products induce cardiac dysfunction?
The pathogenic role of Maillard reaction in the AGING eye
Advanced GLYCATION end products (AGEs): Emerging mediators of skin AGING
N‐Phenacylthiazolium Bromide Inhibits the Advanced GLYCATION End Product (AGE)–AGE Receptor Axis to Modulate Experimental Periodontitis in Rats
Therapeutic interventions for advanced GLYCATION-end products and its receptor-mediated cardiovascular disease
Early-and advanced non-enzymatic GLYCATION in diabetic vascular complications: the search for therapeutics
Heart failure with preserved ejection fraction: emerging drug strategies
The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease
Dynamic changes in myocardial MATRIX and relevance to disease: translational perspectives
AGE–RAGE stress, stressors, and antistressors in health and disease
Role of AGEs-RAGE system in cardiovascular disease
Normalizing aberrant vasculature characteristics generated by elevated EXTRACELLULAR MATRIX stiffness
Advanced GLYCATION end products and diabetic retinopathy
AGING and the cardiac collagen MATRIX: Novel mediators of fibrotic remodelling
Advanced GLYCATION end products: a molecular target for vascular complications in diabetes
Plasma advanced GLYCATION end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure
Disruption of collagen homeostasis can reverse established age-related myocardial fibrosis
Role of advanced GLYCATION end products in carcinogenesis and their therapeutic implications
Advanced GLYCATION Endproducts in AGING Skin
Diabetes-induced alterations in the EXTRACELLULAR MATRIX and their impact on myocardial function
Role of tissue transglutaminase in age-associated ventricular stiffness
Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness
Transglutaminse 2 and EGGL, the protein cross-link formed by transglutaminse 2, as therapeutic targets for disabilities of old age
Advanced GLYCATION end products and diabetic retinopathy
GLYCATION, carbonyl stress and AGEs inhibitors: a patent review
Glycoxidative stress in AGING and pathology
To AGE or not to age. The effect of physical activity and advanced GLYCATION end-products (AGEs) on the vasculature in older individuals
Dichotomous mechanisms of aortic stiffening in high‐fat diet fed young and old B 6 D 2 F 1 mice
The role of advanced GLYCATION end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review
Targeting advanced GLYCATION with pharmaceutical agents: where are we now?
Evaluation of tissue accumulation levels of advanced GLYCATION end products by skin autofluorescence: a novel marker of vascular complications in high-risk patients …
Arterial stiffness and cardiovascular therapy
Dietary advanced GLYCATION end-products: molecular mechanisms and preventive tools
Effects of alagebrium, an AGE BREAKER, on exercise tolerance and cardiac function in patients with chronic heart failure
Advanced GLYCATION end products upregulate lysyl oxidase and endothelin-1 in human aortic endothelial cells via parallel activation of ERK1/2–NF-κB and JNK–AP-1 …
Glycated lysine residues: a marker for non-enzymatic protein GLYCATION in age-related diseases
Betanin reduces the accumulation and cross-links of collagen in high-fructose-fed rat heart through inhibiting non-enzymatic GLYCATION
Diabetes, AGING, and their tissue complications
Mechanical regulation of cardiac AGING in model systems
Alagebrium attenuates methylglyoxal induced oxidative stress and AGE formation in H9C2 cardiac myocytes
Pathologic role of dietary advanced GLYCATION end products in cardiometabolic disorders, and therapeutic intervention
The role of GLYCATION in the pathogenesis of AGING and its prevention through herbal products and physical exercise
Effects of alagebrium, an AGE BREAKER, in patients with chronic heart failure: study design and baseline characteristics of the BENEFICIAL trial
Targeting Fibrosis for the Treatment of Heart Failure: A Role for Transforming Growth Factor‐β
KIOM-79, an inhibitor of AGEs–protein cross-linking, prevents progression of nephropathy in Zucker diabetic fatty rats
AGING: Drugs to eliminate methylglyoxal, a reactive glucose metabolite, and advanced GLYCATION endproducts
Glycated proteome: From reaction to intervention
Advanced GLYCATION end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases
Sodium nitrite de-stiffening of large elastic arteries with AGING: role of normalization of advanced GLYCATION end-products
Advanced GLYCATION end product accumulation in the cardiomyocytes of heart failure patients with and without diabetes
Consequences of advanced GLYCATION end products accumulation in chronic kidney disease and clinical usefulness of their assessment using a non-invasive …
Targeting advanced GLYCATION endproducts and mitochondrial dysfunction in cardiovascular disease
New Approach to Preventing and Treating Diabetes Mellitus: Focus on Advanced GLYCATION End Products (AGE)
Abnormal levels of age-elastin derived peptides in sera of diabetic patients with arterial hypertension
Inhibitory effect of gallic acid on advanced GLYCATION end products induced up-regulation of inflammatory cytokines and MATRIX proteins in H9C2 (2-1) cells
AGE-RAGE axis blockade in diabetic nephropathy: current status and future directions
A simple method to detect plant based inhibitors of GLYCATION induced protein cross-linking
Collagen cross-linking but not collagen amount associates with elevated filling pressures in hypertensive patients with stage C heart failure: potential role of lysyl …
Receptor for advanced GLYCATION end products (RAGE): novel biomarker and therapeutic target for atrial fibrillation
Advanced GLYCATION end products in the pathogenesis of chronic kidney disease
RAGE and TGF-β1 cross-talk regulate EXTRACELLULAR MATRIX turnover and cytokine synthesis in AGEs exposed fibroblast cells
Advanced GLYCATION end products inhibitor
Pharmacological modulation of arterial stiffness
The presence of fructosamine in human aortic valves is associated with valve stiffness
Effects of EXTRACELLULAR MATRIX Stiffness on Muscle Fiber Mechanotransduction Signaling in Aged Rats
Endurance Exercise Training Attenuates Fibrosis and Collagen Cross-linking in Myocardium of Aged Rats
The role of collagen metabolism in CKD-associated arterial senescence: underestimated and underappreciated
The role of titin and EXTRACELLULAR MATRIX remodelling in heart failure with preserved ejection fraction
Glycoxidation and wound healing in diabetes: an interesting relationship
Advanced GLYCATION end‐products accelerate the cardiac AGING process through the receptor for advanced GLYCATION end‐products/transforming growth factor‐β‐Smad …
… management and cosmetic skincare solutions against oxidative GLYCATION and free-radical production as a causal mechanism of diabetic complications and skin AGING
GLYCATION research in amino acids: a place to call home
Dicarbonyls and advanced GLYCATION end-products in the development of diabetic complications and targets for intervention
The role of AGE/RAGE signaling in diabetes-mediated vascular calcification
Effects of maturation and advanced GLYCATION on tensile mechanics of collagen fibrils from rat tail and Achilles tendons
Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
IgG GLYCATION and diabetes: a review
Kidney, heart and brain: three organs targeted by ageing and GLYCATION
The effect of 1 year of Alagebrium and moderate-intensity exercise training on left ventricular function during exercise in seniors: a randomized controlled trial
Uremic toxicity of advanced GLYCATION end products in CKD
Fibrosis, enzymatic and non-enzymatic cross-links in hypertensive heart disease
Sex differences in the association of skin advanced GLYCATION endproducts with knee osteoarthritis progression
Advanced GLYCATION endproducts: from precursors to RAGE: round and round we go
Advanced GLYCATION end-products induce basement membrane hypertrophy in endoneurial microvessels and disrupt the blood–nerve barrier by stimulating …
Basic and clinical research against advanced GLYCATION end products (AGEs): new compounds to tackle cardiovascular disease and diabetic complications
Influence of advanced GLYCATION endproducts on neuronal plasticity
Cardiac AGING–a review
Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using MATRIX-binding polyphenol
More than genes and cells: drug discovery in the ECM
Evaluate the effect of Withania somnifera methanolic extracts as in-vitro antiglycating agents
Soluble receptor for advanced GLYCATION end products and increased aortic stiffness in the general population
Diabetes, non-enzymatic GLYCATION, and AGING
Role of advanced GLYCATION end products in mobility and considerations in possible dietary and nutritional intervention strategies
Ellagic acid inhibits non-enzymatic GLYCATION and prevents proteinuria in diabetic rats
Targeting AGEs signaling ameliorates central nervous system diabetic complications in rats
Cardiovascular effects of 1 year of alagebrium and endurance exercise training in healthy older individuals
Reduction of advanced-GLYCATION end products levels and inhibition of RAGE signaling decreases rat vascular calcification induced by diabetes
The status of GLYCATION in protein aggregation
Ramipril inhibits AGE-RAGE-induced MATRIX metalloproteinase-2 activation in experimental diabetic nephropathy
Remodeling of the rat distal colon in diabetes: function and ultrastructure
Stimulatory effects of non-enzymatic GLYCATION on fibronectin MATRIX assembly
Glucose as an agent of post-translational modification in diabetes—New cardiac epigenetic insights
Fully Atomistic Modelling of Collagen Cross-linking
Nonenzymatic glycosylation: A biochemical link between chronic hyperglycemia and pathophysiologic processes associated with diabetic complications and AGING …
Advanced GLYCATION/glycoxidation endproduct carboxymethyl-lysine and incidence of coronary heart disease and stroke in older adults
Neurite regeneration in adult rat retinas exposed to advanced GLYCATION end-products and regenerative effects of neurotrophin-4
RAGE and cardiovascular disease
Structural alterations in arterial stiffness: role of arterial fibrosis
Advanced GLYCATION endproducts in diabetes and diabetic complications
Chelation therapy for the management of diabetic complications: a hypothesis and a proposal for clinical laboratory assessment of metal ion homeostasis in plasma
Advanced GLYCATION end products (AGEs) in diabetic complications
Localised micro-mechanical stiffening in the ageing aorta
Role of hyperglycemia-induced advanced GLYCATION end product (AGE) accumulation in atherosclerosis
Functional effects of alagebrium (alt-711)–isolated rat carotid artery
ADVANCED GLYCATED END PRODUCTS: A REVIEW
Advanced GLYCATION end-products are associated with the presence and severity of paratonia in early stage Alzheimer disease
Effect of type 2 diabetes-related non-enzymatic GLYCATION on bone biomechanical properties
21. GLYCATION-An imperative target in diabetes and complications
The AGE–RAGE pathway and its relation to cardiovascular disease in patients with chronic kidney disease
Oxidation as an important factor of protein damage: Implications for Maillard reaction
GLYCATION, antiGLYCATION, and deGLYCATION: Their role in AGING mechanisms and geroprotective effects (literature review)
An anti-glycating property roots ethanol and methanol extracts of Withania somnifera on in vitro GLYCATION of elastin protein
Vitamin B6: beyond coenzyme functions
Diabetes-induced cardiovascular disease
N-phenacylthiazolium bromide reduces bone fragility induced by nonenzymatic GLYCATION
Therapeutic agents targeting at AGE-RAGE axis for the treatment of diabetes and cardiovascular disease: a review of clinical evidence
Stiffening of the EXTRACELLULAR MATRIX in skeletal muscle of aged rats and the effect on muscle fiber mechanotransduction
Vascular stiffness and increased pulse pressure in the AGING cardiovascular system
Nitrite modification of EXTRACELLULAR MATRIX alters CD46 expression and VEGF release in human retinal pigment epithelium
Advanced GLYCATION endproduct changes to Bruch’s membrane promotes lipoprotein retention by lipoprotein lipase
Vascular effects of advanced GLYCATION endproducts: clinical effects and molecular mechanisms
Linking RAGE and Nox in diabetic micro-and macrovascular complications
Decreasing Arterial Stiffness and/or Wave Reflections Independently of Mean Arterial Pressure: Effect of Non-antihypertensive Drugs (Part 2)
Diabetes mellitus: novel insights, analysis and interpretation of pathophysiology and complications management with imidazole-containing peptidomimetic …
Role of receptor for advanced GLYCATION end products (RAGE) and its ligands in cancer risk
Vascular mechanics in decellularized aortas and coronary resistance microvessels in type 2 diabetic db/db mice
Novel in Vitro Modification of Bone for an Allograft with Improved Toughness Osteoconductivity
Oxidative stress in early diabetic nephropathy: fueling the fire
RAGE biology, atherosclerosis and diabetes
Increased collagen, per se, may not affect left ventricular function in spontaneously hypertensive rats
Mechanisms of arterial remodeling: lessons from genetic diseases
Coronary microvascular disease as an early culprit in the pathophysiology of diabetes and metabolic syndrome
Arterial stiffness and wave reflections in relation to plasma advanced GLYCATION end products in a Chinese population
A glimpse of various pathogenetic mechanisms of diabetic nephropathy
Glycoxidation of biological macromolecules: a critical approach to halt the menace of GLYCATION
Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy
Skin autofluorescence and pentosidine are associated with aortic stiffening: The Maastricht Study
AGING-Associated Alterations in Myocardial Inflammation and Fibrosis: Pathophysiological Perspectives and Clinical Implications
Advanced GLYCATION end products in diabetes mellitus: mechanism of action and focused treatment
What are new avenues for renal protection, in addition to RAAS inhibition?
Optic nerve head biomechanics in AGING and disease
Jakyakgamcho-tang and Its major component, paeonia lactiflora, exhibit potent anti-GLYCATION properties
Relationship between tissue GLYCATION measured by autofluorescence and pulse wave velocity in young and elderly non-diabetic populations
Methylglyoxal and Other AGEs: Good and Bad Dual Role in the Body
Diabetic cardiomyopathy: pathophysiology and clinical features
Advanced GLYCATION end-products and skin autofluorescence in end-stage renal disease: a review
The clinical usefulness of glycated albumin in patients with diabetes and chronic kidney disease: Progress and challenges
Integrating the myocardial MATRIX into heart failure recognition and management
Proinflammation of AGING central arteries: a mini-review
Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats
Impact of non-enzymatic GLYCATION in neurodegenerative diseases: Role of natural products in prevention
AGE-RAGE Axis in the AGING and Diabetic Heart
A potential role for glycated cross-links in abdominal aortic aneurysm disease
Recent development of plant products with anti-GLYCATION activity: a review
The role of titin and EXTRACELLULAR MATRIX remodelling in HFpEF
Inhibition of advanced GLYCATION end product formation by cymene–A common food constituent
Effect of ageing on left ventricular compliance and distensibility in healthy sedentary humans
Predictive value of advanced GLYCATION end products for the development of post-infarction heart failure: a preliminary report
DNA-aptamers raised against AGEs as a blocker of various AGING-related disorders
Therapeutic modification of arterial stiffness: an update and comprehensive review
Arterial Stiffness and Hypertension–Which Comes First?
Inhibition of miR-25 aggravates diabetic peripheral neuropathy
AGE-RAGE Axis in the AGING and Diabetic Heart: Prime Target for Adjunctive Therapeutic Intervention
How AGEs cause disease: cellular mechanisms
Natural antioxidant polyphenols on inflammation management: Anti-GLYCATION activity vs metalloproteinases inhibition
In vitro GLYCATION of an endothelialized and innervated tissue-engineered skin to screen anti-AGE molecules
Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease
Altered enzyme mechanokinetic cleavage of type I collagen following GLYCATION
The AGE-BREAKER ALT-711 restores high blood flow–dependent remodeling in mesenteric resistance arteries in a rat model of type 2 diabetes
Arterial stiffness gradient
Treatment of arterial remodeling in essential hypertension
Diabetic cardiomyopathy: a hyperglycaemia-and insulin-resistance-induced heart disease
Accumulation of Advanced GLYCATION End Products, Measured by Skin Auto-fluorescence is Associated with Presence and Number of Diabetes Complications; …
AGEs and chronic subclinical inflammation in diabetes: disorders of immune system
Targeting the AGE‐RAGE axis improves renal function in the context of a healthy diet low in advanced GLYCATION end‐product content
Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transGLYCATION
Is increased arterial stiffness a cause or consequence of atherosclerosis?
The mechanisms of inhibition of advanced GLYCATION end products formation through polyphenols in hyperglycemic condition
The role of advanced GLYCATION end products on sarcoplasmic reticulum calcium handling during diabetic cardiomyopathy
Diabetic cardiovascular disease induced by oxidative stress
Molecular mechanisms of diabetic cardiomyopathy
Inhalation therapy for repairing damaged elastin fibers and decelerating elastinolysis in chronic obstructive pulmonary disease
The diverse ligand repertoire of the receptor for advanced GLYCATION endproducts and pathways to the complications of diabetes
A Potential Mechanism for Diabetic Wound Healing: Cutaneous Environmental Disorders
Baking, ageing, diabetes: a short history of the Maillard reaction
Compromised mechanical homeostasis in arterial AGING and associated cardiovascular consequences
Therapeutic potential of DNA-aptamers raised against AGE-RAGE axis in diabetes-related complications
Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: an update
Cellular mechanisms for diastolic dysfunction in the human heart
DamAGING effects of hyperglycemia on cardiovascular function: spotlight on glucose metabolic pathways
Lifelong cyclic mechanical strain promotes large elastic artery stiffening: increased pulse pressure and old age-related organ failure
AGEs and cardiovascular diseases in patients with end-stage renal diseases
Cardiovascular calcifications in old age: mechanisms and clinical implications
Diabetic cardiomyopathy: the case for a role of fructose in disease etiology
The influence of disease and age on human cardiac stem cells
Arterial stiffness
Future treatment of hypertension: shifting the focus from blood pressure lowering to arterial stiffness modulation?
Abundance, localization, and functional correlates of the advanced GLYCATION end‐product carboxymethyl lysine in human myocardium
Arterial stiffening: Causes and consequences
Tuning a 96-well microtiter plate fluorescence-based assay to identify AGE inhibitors in crude plant extracts
Diastolic heart failure: progress, treatment challenges, and prevention
Renoprotective antioxidant effect of alagebrium in experimental diabetes
Mechanisms Involved in Premature AGING in the Heart—Is There an Implication for Cardiac Surgery?
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal-and glyoxal-glycated cysteine, arginine, and lysine residues
Pulse pressure partially explains the higher incidence of cardiovascular disease associated with advanced GLYCATION endproducts and low-grade inflammation …
Effect of diet-derived advanced GLYCATION end products on inflammation
Glucose-induced cell signaling in the pathogenesis of diabetic cardiomyopathy
Recent advances in understanding the biochemical and molecular mechanism of diabetic cardiomyopathy
Advanced GLYCATION end products are direct modulators of β-cell function
Novel therapies in acute and chronic heart failure
Arterial stiffness, vascular calcification and bone metabolism in chronic kidney disease
Dietary interventions to reduce advanced GLYCATION endproducts (AGEs)
Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice
Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment
AGE and RAGE: Hazardous to the Mind?
Study of GLYCATION and drug induced protein CROSSLINKING
Hemoglobin A1c and arterial and ventricular stiffness in older adults
In vitro study of GLYCATION of pyruvate kinase and its effect on activity and proteolytic resistance in absence and presence of aminoguanidine
Role of Amino Acids on Prevention of Nonenzymatic GLYCATION of Lens Proteins in Senile and Diabetic Cataract
Dietary glycotoxins and infant formulas
Amadori albumin in diabetic nephropathy
Quantifying analysis of advanced glycosylation end products (ages) expression in periodontitis patients with diabetes type II
Dynamic Changes in Myocardial MATRIX and Relevance to Disease
Arterial stiffness: A review in type 2 diabetes
Seeds of Cornus officinalis and diabetic cataracts
The pathobiology of diabetic vascular complications—cardiovascular and kidney disease
Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness
IE Diabetic Vitreopathy
Regulatory mechanism of gallic acid against advanced GLYCATION end products induced cardiac remodeling in experimental rats
Advanced GLYCATION end products (AGEs) increase renal lipid accumulation: a pathogenic factor of diabetic nephropathy (DN)
Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin‐treated, apolipoprotein E‐deficient mice
Diabetic kidney disease: a role for advanced GLYCATION end-product receptor 1 (AGE-R1)?
Advanced GLYCATION end-products and their receptor-mediated roles: inflammation and oxidative stress
Functional decorations: post-translational modifications and heart disease delineated by targeted proteomics
The AGING ovary—the poor granulosa cells
Oxidative stress in AGING human skin
Ezrin contributes to impaired podocyte migration and adhesion caused by advanced GLYCATION end products
Diabetic cardiomyopathy: an immunometabolic perspective
Heat stable inhibitors of protein cross-linking from Sri Lankan medicinal plants
Contribution of receptor for advanced GLYCATION end products to vasculature-protecting effects of exercise training in aged rats
Relation of diabetes to coronary artery ectasia: A meta-analysis study.
Role of antihypertensive drugs in arterial ‘de-stiffening’and central pulsatile hemodynamics
Novel therapies for diabetic kidney disease
Pharmacological evaluation of novel alagebrium analogs as methylglyoxal scavengers in vitro in cardiac myocytes and in vivo in SD rats
The inhibitory activities of the edible green alga Capsosiphon fulvescens on rat lens aldose reductase and advanced GLYCATION end products formation
Pyridoxamine improves survival and limits cardiac dysfunction after MI
Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms
Arterial stiffness, pulse pressure, and cardiovascular disease—is it possible to break the vicious circle?
Higher levels of advanced GLYCATION endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype
Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced GLYCATION end products in dilated cardiomyopathy
Diabetes and advanced GLYCATION end products
AGEs induce ectopic endochondral ossification in intervertebral discs
Structural proteins and arterial ageing
Differential impact of glucose levels and advanced GLYCATION end-products on tubular cell viability and pro-inflammatory/profibrotic functions
Role of Smad1 in diabetic nephropathy: molecular mechanisms and implications as a diagnostic marker
Diabetic cardiomyopathy—What do we know about it?
Arterial stiffness and stroke: de-stiffening strategy, a therapeutic target for stroke
Diabetes and complications: cellular signaling pathways, current understanding and targeted therapies
Abdominal aortic aneurysms and diabetes mellitus
Lipoprotein GLYCATION in diabetes mellitus
Methylglyoxal promotes oxidative stress and endothelial dysfunction
Changes in the myocardial interstitium and contribution to the progression of heart failure
Identifying and interpreting novel targets that address more than one diabetic complication: a strategy for optimal end organ protection in diabetes
Left ventricular hypertrophy regression and allopurinol: more questions than answers
Predictors and prevention of diabetic cardiomyopathy
Circulating levels of carboxy‐methyl‐lysine (CML) are associated with hip fracture risk: the Cardiovascular Health Study
Aortic stiffness: current understanding and future directions
The reality of AGING viewed from the arterial wall
Arterial stiffness
Oxidative stress-related mechanisms and antioxidant therapy in diabetic retinopathy
Intraoperative sRAGE kinetics
Advanced GLYCATION end products and schizophrenia: A systematic review
Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes
Nox-4 and progressive kidney disease
Metabolic Karma—the atherogenic legacy of diabetes: the 2017 Edwin Bierman Award Lecture
CCN-2 is up-regulated by and mediates effects of MATRIX bound advanced glycated end-products in human renal mesangial cells
Advanced GLYCATION end products promote proliferation of cardiac fibroblasts by upregulation of K Ca 3.1 channels
Advanced GLYCATION end-products: modifiable environmental factors profoundly mediate insulin resistance
VASCULAR STIFFENING IN ATHEROSCLEROSIS: CELL CONTRACTILITY AND MATRIX MECHANICAL HETEROGENEITIES MEDIATE BARRIER INTEGRITY
Role of advanced GLYCATION end products related to the onset of diabetic kidney disease complications
Toxicity of protein and DNA-AGEs in neurodegenerative diseases (NDDs) with decisive approaches to stop the deadly consequences
Skin autofluorescence is associated with inappropriate left ventricular mass and diastolic dysfunction in subjects at risk for cardiovascular disease
Advanced GLYCATION end products, diabetes, and the brain
Age-and diabetes-induced regulation of oxidative protein modification in rat brain and peripheral tissues: Consequences of treatment with antioxidant pyridoindole
Receptor for advanced GLYCATION endproducts and progressive kidney disease
Osseous wound repair under inhibition of the axis of advanced GLYCATION end-products and the advanced GLYCATION end-products receptor
Dietary AGEs in the Development and Progression of Chronic Kidney Disease
Similarities and differences between the pathogenesis and pathophysiology of diastolic and systolic heart failure
Pathophysiology and medical treatment of carotid artery stenosis
Changes in the mechanical and biochemical properties of aortic tissue due to cold storage
GLYCATION: the angiogenic paradox in AGING and age-related disorders and diseases
Advanced GLYCATION end-products and outcome in heart failure patients with preserved and reduced ejection fraction
An in vitro study on the non-enzymatic GLYCATION of melamine and serum albumin by reducing sugars
The possible role of advanced GLYCATION endproducts (AGEs) in experimentally-induced ischemic brain damage.
Strategies for achieving healthy vascular AGING
Arterial stiffness, cognitive impairment and dementia: confounding factor or real risk?
Significance of Advanced GLYCATION End Products in AGING-Related Disease
Determinants of progression of aortic stiffness in hemodialysis patients: a prospective longitudinal study
Dietary glycotoxins exacerbate progression of experimental fatty liver disease
Substrate stiffness regulates PDGF-induced circular dorsal ruffle formation through MLCK
The effect of BAPN on heart structure and function in the angiotensin II hypertensive mouse
Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells
Novel Treatments in Diabetic Nephropathy
Regenerative therapies for diabetic microangiopathy
Arterial stiffness and pulse pressure in CKD and ESRD
Age-related changes in the mechanical properties of large arteries
Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: possible underlying mechanisms
Curcumin ameliorates arterial dysfunction and oxidative stress with AGING
Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular AGING
Amino carbonylation of epidermal basement membrane inhibits epidermal cell function and is suppressed by methylparaben
Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats
5.2 Integrin function in heart fibrosis: mechanical strain, transforming growth factor-beta 1 activation, and collagen GLYCATION
Arterial function in cardio-metabolic diseases: from the microcirculation to the large conduits
Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options
Osteoarthritis: an update with relevance for clinical practice
Prevention of protein GLYCATION by natural compounds
The question is, my dear watson, why did the dog not bark?: The joslin 50-year medalist study
Diabetic nephropathy–complications and treatment
Antioxidants in health, disease and AGING
Factors associated with pentosidine accumulation in the human vitreous
Management of limited joint mobility in diabetic patients
Interrelationship between diabetes mellitus and heart failure: The role of peroxisome proliferator-activated receptors in left ventricle performance
Advanced GLYCATION end product 3 (AGE3) suppresses the mineralization of mouse stromal ST2 cells and human mesenchymal stem cells by increasing TGF-β …
Flow (shear stress)-mediated remodeling of resistance arteries in diabetes
Elastin, Calcium and Age-Related Stiffening of the Arterial Wall
Comparative evaluation of fosinopril and herbal drug Dioscorea bulbifera in patients of diabetic nephropathy
Toward regeneration of articular cartilage
Inhibitory effects and actions of pentacyclic triterpenes upon GLYCATION
The renal endothelium in diabetic nephropathy
AGE–RAGE interaction and oxidative stress in obesity-related renal dysfunction
A review on advanced GLYCATION end-products (age) and their role in diabetes mellitus
Advanced GLYCATION end products in children with type 1 diabetes and early reduced diastolic heart function
Tandem inhibition of PKC in Diαβetic nephropathy: it takes two to tango?
The efficiency of compounds with α-amino-β-mercapto-ethane group in protection of human serum albumin carbonylation and cross-linking with methylglyoxal
Blocking Gastrointestinal Absorption of AGEs
AGING-induced biological changes and cardiovascular diseases
Tiny molecule, big power: multi-target approach for curcumin in diabetic cardiomyopathy
AGE and RAGE: Hazardous to the Mind? A plea for translational work
How exercise may amend metabolic disturbances in diabetic cardiomyopathy
Collagen processing and its role in fibrosis
PROTECTIVE EFFECT OF SOME NATURAL PRODUCTS ON GLUCOSE OR METHYLGLYOXAL INDUCED GLYCATION OF SUPEROXIDE DISMUTASE
AGING in blood vessels. Medicinal agents FOR systemic arterial hypertension in the elderly
Increased levels of advanced GLYCATION end products positively correlate with iron overload and oxidative stress markers in patients with β-thalassemia major
The effectiveness of the peel extract of water chestnut (Trapa bispinosa Roxb.) in an α-crystallin GLYCATION model with glyoxal
Advanced GLYCATION End Products And Risks For Chronic Diseases: Intervening Through Lifestyle Modification
Aortic stiffness is reduced beyond blood pressure lowering by short-term and long-term antihypertensive treatment: a meta-analysis of individual data in 294 patients
Halting arterial AGING in patients with cardiovascular disease: hypolipidemic and antihypertensive therapy
Current concepts in the management of diabetic nephropathy
Coronary Microvascular Disease as an Early Culprit in
Multiligands/Rage Axis: an Emerging Actor in Tumour Angiogenesis
Receptor for AGEs (RAGE) as mediator of NF-kB pathway activation in neuroinflammation and oxidative stress
Skin autofluorescence as a marker of cardiovascular risk in children with chronic kidney disease
Dietary AGEs and their role in health and disease
The low AGE diet: a neglected aspect of clinical nephrology practice?
Phaseolamin treatment prevents oxidative stress and collagen deposition in the hearts of streptozotocin-induced diabetic rats
Understanding the viscoelastic behavior of collagen matrices through relaxation time distribution spectrum
Synergistic effects of telmisartan and pyridoxamine on early renal damage in spontaneously hypertensive rats
Study of advanced GLYCATION endproducts (AGEs) of human fibrinogen and nucleobases with methyl glyoxal: An in vitro investigation of ages formation
Heart failure with preserved ejection fraction: the new devil in the pandemic
The AGING Arterial Wall
Targeting inflammation in diabetic nephropathy: a tale of hope
Interference of amlodipine combined with ALT-711 on arteriosclerosis in spontaneously hypertensive rats
Novel Mechanistic Insights into the Role of Advanced GLYCATION End Products in the Development of Diabetic Cardiomyopathy
Relation between glycemia level and common carotid artery intima-media thickness in females
Expression and regulation of facilitative glucose transporters in equine insulin-sensitive tissue: from physiology to pathology
Cardiovascular Complications in Renal Failure: Implications of Advanced GLYCATION End Products and Their Receptor RAGE
Protective role of sulphoraphane against vascular complications in diabetes
Healthy lifestyle-based approaches for successful vascular AGING
Effects of mesenchymal stromal cells on diabetic cardiomyopathy
Controlling the receptor for advanced GLYCATION end‐products to conquer diabetic vascular complications
A comparison of dicarbonyl stress and advanced GLYCATION endproducts in lifelong endurance athletes vs. sedentary controls
The two faces of hypertension: role of aortic stiffness
Receptor for advanced GLYCATION end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes
Aortic stiffness as a surrogate endpoint to micro-and macrovascular complications in patients with type 2 diabetes
The role of advanced GLYCATION end-products in cancer disparity
A novel in vitro method to identify protein GLYCATION inhibitors
Hypertension and chronic kidney disease: respective contribution of mean and pulse pressure and arterial stiffness
Role of Rap1a in AGE/RAGE-mediated Signaling in Type II Diabetes Mellitus
Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By EXTRACELLULAR MATRIX Stiffness
Novel drug treatment for diabetic nephropathy
Advanced GLYCATION endproducts and diabetes. Beyond vascular complications
Arterial stiffness
Plant-derived agents with anti-GLYCATION activity
Diabetic peripheral neuropathy: current perspective and future directions
Animal models of heart failure with preserved ejection fraction
Diabetic Nephropathy: Current and Novel Therapeutic Approaches to Prevent Its Development and Progression
A novel in vitro method to detect inhibitors of protein GLYCATION
Regulation of RAGE for attenuating progression of diabetic vascular complications
Cardiovascular Complications
MATRIX metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and …
Renal nerve ablation reduces augmentation index in patients with resistant hypertension
Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like …
Tendinopathy in diabetes mellitus patients—epidemiology, pathogenesis, and management
Molecular mechanisms associated with diabetic endothelial–erectile dysfunction
The multiple faces of RAGE–opportunities for therapeutic intervention in AGING and chronic disease
Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia
Elevated glucose levels promote contractile and cytoskeletal gene expression in vascular smooth muscle via Rho/protein kinase C and actin polymerization
Inhibition of Na+/H+ exchanger 1 attenuates renal dysfunction induced by advanced GLYCATION end products in rats
Attenuation of glucose-induced myoglobin GLYCATION and the formation of advanced GLYCATION end products (AGEs) by (R)-α-lipoic acid in vitro
Localized micro-and nano-scale remodelling in the diabetic aorta
Type 2 diabetes and cognitive impairment: linking mechanisms
Mitofusin 2 attenuates the histone acetylation at collagen IV promoter in diabetic nephropathy
L-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced GLYCATION end products, and tumor necrosis factor–α levels in patients with type 2 …
How drugs influencing central blood pressure prevent atherosclerosis complications?
Mechanism for the development of bone disease in diabetes: increased oxidative stress and advanced GLYCATION end products
Anti-glycative potential of triterpenes: a mini-review
Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity
Pathophysiology of the diabetic kidney
The role of human serum carnosinase 1 in diabetic nephropathy
Phytate decreases formation of advanced GLYCATION end-products in patients with type II diabetes: Randomized crossover trial
Panvascular risk factor–diabetes
Trans-resveratrol mitigates type 1 diabetes-induced oxidative DNA damage and accumulation of advanced GLYCATION end products in glomeruli and tubules of rat …
Aldolase B Knockdown Prevents High Glucose-Induced Methylglyoxal Overproduction and
Heart failure with preserved ejection fraction: current understanding and emerging concepts
Heart failure with preserved ejection fraction and future pharmacological strategies: a glance in the crystal ball
Abnormal thiamine-dependent processes in Alzheimer’s Disease. Lessons from diabetes
Molecular mechanism of diabetic cardiomyopathy and modulation of microRNA function by synthetic oligonucleotides
The vulnerable myocardium
30. Optic nerve head biomechanics in health, AGING, and disease
Meta-profiles of gene expression during AGING: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature
Pharmacologic targets and peritoneal membrane remodeling
Molecular players at the intersection of obesity and osteoarthritis
Biomolecular basis of the role of diabetes mellitus in osteoporosis and bone fractures
Pregnancy and Hypertension
Pathological Role of AGEs in Osteoporosis
Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in AGING male rats
Anti-GLYCATION skin care–a promising approach for young, mature and diabetic skin
Mesenchymal stem cells: a future experimental exploration for recession of diabetic nephropathy
The Role of Cortical and Cancellous Bone Quality on Vertebral Fragility
Modeling of bone failure by cohesive zone models
Antioxidant and AntiGLYCATION effect of some Phytochemicals
Diabetic Cardiomyopathy: Current Status
Diabetes mellitus and rhegmatogenous retinal detachment
Vascular stiffness and AGING in HIV
Longitudinal left ventricular function in normotensive prediabetics: a tissue Doppler and strain/strain rate echocardiography study
A constituent-based model of age-related changes in conduit arteries
Diabetic cardiomyopathy: A new perspective of mechanistic approach
AGING and vascular endothelial function in humans
Present insights on cardiomyopathy in diabetic patients
A method to quantify intracellular GLYCATION in dermal fibroblasts using liquid chromatography coupled to fluorescence detection–Application to the selection of …
Role of protein kinase C in podocytes and development of glomerular damage in diabetic nephropathy
Diabetes Mellitus and Limited Joint Mobility in the Upper Extremity
Breakthrough in heart failure with preserved ejection fraction: are we there yet?
Are targeted therapies for diabetic cardiomyopathy on the horizon?
About AGEs
Advanced GLYCATION end products overload might explain intracellular cobalamin deficiency in renal dysfunction, diabetes and AGING
Advances in the non-invasive assessment of vascular dysfunction in metabolic syndrome and diabetes: focus on endothelium, carotid mechanics and renal vessels
Structures required of polyphenols for inhibiting advanced GLYCATION end products formation
Skin autofluorescence, as marker of accumulation of advanced GLYCATION endproducts and of cumulative metabolic stress, is not increased in patients with …
Measurement of arterial stiffness: a novel tool of risk stratification in hypertension
Vascular Stiffening Regulates Endothelial Permeability And Smooth Muscle Cell Motility
Associations between structural and functional changes to the kidney in diabetic humans and mice
Heart failure with preserved ejection fraction: a clinical dilemma
ImAGING in diabetic cardiomyopathy
Biology of diabetic neuropathy
Dynamic micro-and macrovascular remodeling in coronary circulation of obese Ossabaw pigs with metabolic syndrome
AGING biology in the kidney
Mechanisms of diabetic complications
Protein GLYCATION and oxidative stress in pathophysiology of diabetic complications
Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond
Heart failure with preserved ejection fraction: an ongoing enigma
Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the AGING heart
Structural and functional properties, chaperone activity and posttranslational modifications of alpha-crystallin and its related subunits in the crystalline lens: N …
Improved diabetes control in the elderly delays global cognitive decline
Dicarbonyls induce senescence of human vascular endothelial cells
Arterial stiffness in chronic kidney disease: an update
Glucose, insulin and potential strategies of vascular stiffening
S100B Expression Modulates Diabetic Myocardium following Myocardial Infarction and Development of Diabetes
New insight into the molecular drug target of diabetic nephropathy
Study of association between carboxymethyllysine and circulating soluble receptor for advanced GLYCATION end products and cardiovascular dysfunction in …
The AGE of Biomaterials: Preserving the Myocardium after Infarction to Promote Heart Repair and Function
Worse cardiac remodeling in response to pressure overload in type 2 diabetes mellitus
Protein modification and maintenance systems as biomarkers of ageing
Role of serum biomarkers in early detection of diabetic cardiomyopathy in the West Virginian population
The impracticality of biomedical rejuvenation therapies: translational and pharmacological barriers
Stiffness-induced endothelial DLC-1 expression forces leukocyte spreading through stabilization of the ICAM-1 adhesome
Glucotoxic mechanisms and related therapeutic approaches
Regulation of AGING in yeast by GLYCATION inhibitors
A review on role of advanced GLYCATION end products (ages) in rheumatoid arthritis
Barrier Maintenance in Neovessels
Slowing the AGING process
Attenuated age-related carotid arterial remodeling in adults with a high level of cardiorespiratory fitness
RAGE deletion confers renoprotection by reducing responsiveness to transforming growth factor-β and increasing resistance to apoptosis
Diabetic microvascular disease: an endocrine society scientific statement
The vascular smooth muscle cell: a therapeutic target in type 2 diabetes?
Challenging the dogma of mitochondrial reactive oxygen species overproduction in diabetic kidney disease
Salvianolic acid A protects against diabetic nephropathy through ameliorating glomerular endothelial dysfunction via inhibiting AGE-RAGE signaling
Effect of KIOM-79 on diabetes-induced myocardial fibrosis in Zucker diabetic fatty rats
Metabolic effects of metformin in the failing heart
Chelation therapy: overlooked in the treatment and prevention of diabetes complications?
Investigation of circulating RAGE in patients with cardiovascular disease
Food processing: The influence of the maillard reaction on immunogenicity and allergenicity of food proteins
Development and evaluation of delayed CT arthrography of cartilage
New molecular insights in diabetic nephropathy
Limited joint mobility syndrome in diabetes mellitus: a minireview
New drugs under development for cardiovascular prevention
Insulin resistance and progression of heart failure in the older adult
Advanced GLYCATION end products induced immune maturation of dendritic cells controls heart failure through NF-κB signaling pathway
VU Research Portal
IL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function
Diabetes‐induced mechanophysiological changes in the esophagus
Effect of AGING on metabolic pathways in endothelial progenitor cells
Targeting Blood Pressure Lowering and the Sympathetic Nervous System
Challenges in vascular tissue engineering for diabetic patients
Distinct myocardial targets for diabetes therapy in heart failure with preserved or reduced ejection fraction
Elucidating molecular mechanism of antiGLYCATION compounds by proteomic approaches
The role of fibrinogen GLYCATION in ATTR: evidence for chaperone activity loss in disease
Stain-free LED scanning lifetime imAGING system for diabetes modified tissue matrices
Diabetic Glomerulopathy
Inhibitory effect of Arachis hypogaea (Peanut) and its phenolics against methylglyoxal-derived advanced GLYCATION end product toxicity
Finite element modeling of collagen fibers in the mechanical interaction between cells and the EXTRACELLULAR MATRIX
The arterial microenvironment: the where and why of atherosclerosis
Current update in the management of diabetic nephropathy
Anti-Ageing Medicines: The Facts, What Works and What Doesn’t
New approaches to the treatment of nephropathy in diabetes
Early functional and structural microvascular changes in hypertension related to AGING
Glucose, Insulin and Potential
Heart and Arterial AGING
Novel therapies for diabetic kidney disease: storied past and forward paths
Diastolic dysfunction in hypertension
Could Advanced GLYCATION End Products Explain the Poor Response to Controlled Ovarian Hyperstimulation in Obese Women?
Blood proteome characterization of the interplay between GLYCATION and aspirin-mediated acetylation in vitro and in diabetic patients
AGEs promote oxidative stress and induce apoptosis in retinal pigmented epithelium cells RAGE-dependently
New insights into arterial stiffening: does sex matter?
The Evolving Face of Heart Failure Associated with Elevated Cardio-Metabolic Risk Factors
Antidiabetic functional foods with antiGLYCATION properties
Pathology of AD
Do advanced GLYCATION end products (AGEs) contribute to the comorbidities of polycystic ovary syndrome (PCOS)?
α‑lipoic acid can greatly alleviate the toxic effect of AGES on SH‑SY5Y cells
Treatment of chronic kidney disease
Soluble RAGEs—Prospects for treating & tracking metabolic and inflammatory disease
Inhibitory efficacy of Ligularia fischeri against aldose reductase and advanced GLYCATION end products formation
An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes
Cyclopeptide alkaloids: isolation, structure elucidation, antiplasmodial activity and AGEs inhibiting properties
The role of matricellular proteins Nov and Wisp1 in AGING and myocardial infarction
Targeting Signaling Pathways
Effect of Nebivolol and Lifestyle Modification on Large Artery Stiffness in Middle-Aged and Older Hypertensive Adults
Brachial-ankle PWV: current status and future directions as a useful marker in the management of cardiovascular disease and/or cardiovascular risk factors
RAGE in the pathophysiology of skeletal muscle
Vascular changes in type 2 diabetes mellitus: Application to restenosis after stenting
Diabetic microangiopathy—etiopathogenesis, new possibilities in diagnostics and management
Small artery remodeling in obesity and insulin resistance
Vascular Complications in Diabetes 15
AGING Does Not Affect Radial Viscoelastic Behavior of the Left Ventricle
A histopathological investigation of Tenon’s capsule in diabetic eyes
AGING IN BLOOD VESSELS. MEDICINAL AGENTS FOR SYSTEMIC ARTERIAL HYPERTENSION IN THE ELDERLY.
Metabolic dysfunction in diabetic cardiomyopathy
EVALUATION OF REACTIVE GLUCOSE BY-PRODUCTS DICARBONYLS AND GLYCATED HAEMOGLOBIN IN HYPERGLYCEMIC PATIENTS
Coronary arterioles in type 2 diabetic (db/db) mice undergo a distinct pattern of remodeling associated with decreased vessel stiffness
Vascular Complications in Diabetes
Effects of diabetes-induced hyperglycemia in the heart: Biochemical and structural alterations
Coronary microvascular remodeling in type 2 diabetes: synonymous with early AGING?
Peripheral Nerve Disorders: Chapter 34. Biology of diabetic neuropathy
Roles of claudin-5 and von Willebrand factor in patients with rheumatoid arthritis
Endothelial dysfunction—a major mediator of diabetic vascular disease
Study of antioxidant activity of formononetin by in vitro method
Type-1 pericytes participate in fibrous tissue deposition in aged skeletal muscle
Journal of Pharmaceutical and Scientific Innovation
Effect of mononuclear cells versus pioglitazone on streptozotocin-induced diabetic nephropathy in rats
The biology of AGING: implications for diseases of AGING and health care in the twenty-first century
Cardiovascular tissue engineered constructs for patients with diabetes
Exercise training ameliorates MATRIX metalloproteinases 2 and 9 messenger RNA expression and mitigates adverse left ventricular remodeling in streptozotocin …
Off the beaten renin–angiotensin–aldosterone system pathway: New perspectives on antiproteinuric therapy
Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease
Functional aortic stiffness: role of CD4+ T lymphocytes
Cellular stress responses, hormetic phytochemicals and vitagenes in AGING and longevity
Can targeting the incretin pathway dampen RAGE-mediated events in diabetic nephropathy?
Heart failure with preserved ejection fraction: current management and future strategies
Deficiency in Mitochondrial Complex I Activity Due to Ndufs6 Gene Trap Insertion Induces Renal Disease
Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
Dialysis initiation and clinical outcomes in chronic kidney disease: Role of education and biomarkers
AGE/RAGE as a mediator of insulin resistance or metabolic syndrome: another aspect of metabolic memory
THE AGE-RELATED MACULAR DEGENERATION AS A VASCULAR DISEASE: CONTRIBUTIONS TO THE NON-PHARMACOLOGICAL INTERVENTIONS AND …
Metabolic and biochemical stressors in diabetic cardiomyopathy
Anagliptin, a dipeptidyl peptidase-4 inhibitor ameliorates arterial stiffness in association with reduction of remnant-like particle cholesterol and alanine transaminase …
AGING disorders of the eye: Challenges and approaches for their treatment
Hyperglycemia impairs atherosclerosis regression in mice
Metabolic alterations in diabetic cardiomyopathy
The role of fibrinogen GLYCATION in ATTR: evidence for chaperone activity loss in
Cardiac effects of HDL and its components on diabetic cardiomyopathy
Testing isotopic labeling with [13C6] glucose as a method of advanced GLYCATION sites identification
Anthranilic acid derivatives: novel inhibitors of protein GLYCATION and the associated oxidative stress in the hepatocytes
Effect of some plant extract on non enzymatic glycosylation of IgG under in-vitro conditions
A comparative study of levels of methylglyoxal and reduced glutathione in different organs of rats treated with high carbohydrate diets
Effects of adipose-derived stem cells plus insulin on erectile function in streptozotocin-induced diabetic rats
Impact of Dietary Polyphenols on Arterial Stiffness: Outline of Contributing Mechanisms
Role of renin-angiotensin-aldosterone system activation in promoting cardiovascular fibrosis and stiffness
Heart failure with preserved ejection fraction: fighting misconceptions for a new approach
Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status
Preventative role of alpha-lipoic acid, curcumin and ginger in inhibiting myoglobin GLYCATION and the formation of advanced GLYCATION end products (AGEs)
Diet with high content of advanced GLYCATION end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic …
Microvascular modifications in diabetic retinopathy
Study of oxidation and non-enzymatic glycosylation posttranslational modifications using a proteomic approach
The role of invasive diagnostics and its impact on the treatment of dilated cardiomyopathy: a systematic review
Diabetic cardiomyopathy: current and future therapies. Beyond glycemic control
The inhibitory effect of selenium nanoparticles on protein GLYCATION in vitro
Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function
Effects of Vascular Nitric Oxide Bioactivity and Vascular Ageing on Arterial Blood Pressure and Flow Waveforms
Targeting mitochondria and reactive oxygen species-driven pathogenesis in diabetic nephropathy
The Roles of Oxidative Stress, Inflammation and Adaptive Immunity in Aortic Stiffening
Perturbation of cellular and vascular function by hyperglycaemia and hyperlipidaemia and their role in cardiovascular disease
The role of glucosamine-induced ER stress in diabetic atherogenesis
Evolving insights into the pathophysiology of diabetic neuropathy: implications of malfunctioning glia and discovery of novel therapeutic targets
Hyperglycemia-induced cardiac contractile dysfunction in the diabetic heart
Sex Differences in Cardiovascular and Cerebrovascular Physiology, Disease, and Signaling Mechanisms: New insights into arterial stiffening: does sex matter …
Inhibitory activities of tree bark extracts against AGEs formation and their correlation with phenolic components
Étude de l’impact de la GLYCATION sur la guérison des plaies cutanées
Different impact of hemodialysis vintage on cause-specific mortality in long-term hemodialysis patients
Visualizing the RAGE: Molecular ImAGING After MI Provides Insight Into a Complex Receptor
Age associated endothelial dysfunction: Role of oxidative stress, inflammation and Western Diet
Heart failure with normal ejection fraction: a growing pandemic
Assessment of oral glycine and lysine therapy on receptor for advanced GLYCATION end products and transforming growth factor beta expression in the kidney of …
Diabetic Membrane Repair Deficiency and Repair Promotion By Vitamin E
Clinical implications for patients with heart failure with preserved ejection fraction
Dicarbonyl stress and dysfunction of the glyoxalase system in periodontal diseases
GLUCOTOXICITY, PROTEIN GLYCATION AND ADIPOSE TISSUE DYSFUNCTION
DIABETES AND TENDINOPATHIES
Natural compounds with anti-ageing activity
Association of metabolic syndrome with the cardioankle vascular index in asymptomatic Korean population
Emerging role of epigenetics and miRNA in diabetic cardiomyopathy
Enhanced formation of methylglyoxal-derived advanced GLYCATION end products in Arabidopsis under ammonium nutrition
Calcium signaling in the ventricular myocardium of the Goto-Kakizaki type 2 diabetic rat
Diabetic cardiomyopathy: ongoing controversies in 2012
Carbonylation induces heterogeneity in cardiac ryanodine receptor function in diabetes mellitus
Effects of conjugated linoleic acid on cardiomyocyte abnormalities in diabetic cardiomyopathy
Cardiovascular AGING: the next frontier in cardiovascular prevention
New antihypertensive drugs under development
Elevated plasma B-type natriuretic peptide concentration and resistive index, but not decreased aortic distensibility, associate with impaired blood flow at popliteal …
Pathological effects of exosomes in mediating diabetic cardiomyopathy
Therapy for diabetic neuropathy: an overview
The role of inflammation in diabetic cardiomyopathy
Literature-related discovery techniques applied to ocular disease: a vitreous restoration example
Time-course morphological and functional disorders of the kidney induced by long-term high-fat diet intake in female rats
Preventive aspects in peripheral artery disease
Blood pressure and arterial load after transcatheter aortic valve replacement for aortic stenosis
Novel therapeutic targets in the management of atrial fibrillation
Optimization of Biophotonics and Optomechanics for Frequency Domain Tissue Fluorescence Measurements
Immune modulation of vascular stiffening
In vitro efficacy evaluation for prevention of diabetes and diabetic complications using Aster sphathulifolius
Regulation and bioactivity of the CCN family of genes and proteins in obesity and diabetes
Oxidative stress and inflammation as a response to glucose exposure and dialysis
Pawan K. Singal, Adriane Belló-Klein
Vasculopathy in the setting of cardiorenal syndrome: roles of protein-bound uremic toxins
Signaling in Diabetes and Metabolic Syndrome
Myocardial reverse remodeling: how far can we rewind?
Differential cardiovascular profiles of sodium-glucose cotransporter 2 inhibitors: critical evaluation of empagliflozin
Amyloid beta: structure, biology and structure-based therapeutic development
CORNEAL HYSTERESIS: LOOKING BEYOND GLAUCOMA: A SYSTEMATIC REVIEW
Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imAGING
Large arterial stiffness and associated cardiovascular risk factors in black South Africans
Increased Bacterial Adherence and Decreased Bacterial Clearance in Urinary Tract Infections with Diabetes Mellitus
AntiGLYCATION and antioxidant properties of Momordica charantia
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells
Interdisciplinary challenges and promising theranostic effects of nanoscience in Alzheimer’s disease
The role of reactive oxygen species in microvascular remodeling
Traditional, Nontraditional, and Uremia-Related Threats for Cardiovascular Disease in Chronic Kidney Disease
Carbohydrate Directed Photoaffinity Labelling
The diagnosis and treatment of myocardial and arterial dysfunction in Marfan Syndrome.
Drugs for Diabetic Nephropathy-full review
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients …
Li-Li Tong and Sharon Adler
Jessica Cervantes, Ana Paula Lamas, Andre Lencastre, Daniel Coelho de Sá, and Antonella Tosti
Formation and inhibition of advanced GLYCATION endproducts in meat and model systems
Cardiac adaptation in prolonged inverted bats (Eidolon helvum)
Deciphering non-coding RNAs in cardiovascular health and disease
Role of oxidative stress and targeted antioxidant therapies in experimental models of diabetic complications
HIGH RESOLUTION MASS SPECTROMETRIC STRATEGIES IN DRUG DISCOVERY FOR THE INVESTIGATION OF COVALENT AND NON-COVALENT …
Protein folding and aggregation into amyloid: the interference by natural phenolic compounds
Endothelial Dysfunction in Diabetes: An Update on Mechanisms and Therapeutic Targets
Chemical Approaches to Modulate Biological Processes: Unique Activity of N-Phenacylthiazolium Compounds, Bacterial Cell Wall Engineering and Other …
Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status
Treating heart failure with preserved ejection fraction related to arterial stiffness. Can we kill two birds with one stone?
Mesenchymal stem cells as therapeutic candidates for halting the progression of diabetic nephropathy
N⁶-formylation of lysine: a pathological secondary modification of proteins
Oxidative Stress in Retinal Diseases
Efficacy of sitagliptin in retarding the progression of albuminuria and assessing its safety and efficacy in patients with diabetic nephropathy
Effects of vitamin D restricted diet administered during perinatal and postnatal periods on the penis of Wistar rats
Mediators of renal cell injury in diabetic kidney disease: A role for ADAM17
The Arterial Pulse: Vascular Biology, Vascular Function Testing, and Therapies
Basic Science Liver
Antioxidants in health and disease
Obesity in a model of haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
Pre-Diabetes, Cardiovascular Risk Factors, Arterial Stiffness—ADMA: Mechanisms of Pre-Diabetes and Diabetes: Modulation of Cardiac Tissues
Neurodegeneration is dependant on microglial proximity and nitric oxide production
Probiotic Supplementation, The Gut Microbiota, and Cardiovascular Health
Cellular and molecular mechanisms of diabetic glomerulopathy
Diabetes and chronic oxidative stress. A perspective based on the possible usefulness of ozone therapy
Effects of phosphate binding with sevelamer carbonate on cardiovascular structure and function in patients with early chronic kidney disease
Identification and characterization of enzymes responsible for methylglyoxal overproduction in the metabolic syndrome
Investigation into the role of the hexosamine biosynthesis pathway in hyperglycemia-induced atherosclerosis
Short-term rapamycin persistently improves cardiac function after cessation of treatment in aged male and female mice.
Implications of metal binding and asparagine deamidation for amyloid formation
Functional Genomics of Ageing and Its Modulation by Diet
The Role of the IRE1α Pathway in Vascular Stiffening and Fibrosis
Induced pluripotent stem (iPS) cells inhibit apoptosis and fibrosis in streptozotocin-induced diabetic rats
Daily monitoring of arterial stiffness in children with end-stage renal disease
Arteries and veins
… of DNAzymes catalyzing thymine dimer photoreactivation and phosphodiester cleavage using a new method of iodine-mediated phosphorothioate cross-linking
Investigating Type 2 Diabetes Related Biosensing and Amyloid Peptide Fibrillation
Potential of Curcuma Longa and Withania Somnifera for Diabetes and Associated Neurological Comorbidities
Review of erectile dysfunction in diabetic animal models
The AGING Gap Between Species
Daily Monitoring of Arterial Stiffness in Children with End-stage Renal Disease
Reduction of arterial stiffness after kidney transplantation: a systematic review and Meta‐Analysis
Vascular Stem and Progenitor Cells in Diabetic Complications
Phytopharmacology of Ashwagandha as an anti-diabetic herb
Stiff Heart and Stiff Arteries. Could We Soften Both?
Molecular Mechanisms Underlying the Prevention of Glucose-Induced Life Span Reduction by the Polyphenol Quercetin in the mev-1 Mutant of Caenorhabditis …
Physiology and pathophysiology of carnosine
The physical measurement of bone
The effect of spices on carboxymethyllyinse levels in biscuits
Flavor addition in dairy products: health benefits and risks
Heart failure with preserved ejection fraction
The eggshell: structure and protective function
The Role of Intestinal Derived Remnant Lipoproteins in the Progression of Atherosclerosis in Animal Models of Type 1 and Type 2 Diabetes.
Traditional, Nontraditional, and Uremia-Related Threats for Cardiovascular Disease in Chronic Kidney
Drugs and the peroxisome proliferator activated receptors
Heart failure: novel therapeutic approaches
Is endothelial dysfunction the one to blame in Heart Failure with Preserved Ejection Fraction?
Pathophysiologie diabetischer Spätschäden
Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery
Mitochondria and Oxidative Stress in Diabetes
Effect of age and chronic hypoxia on oxidative status, mitochondria and apoptosis in rat liver
The role of antioxidants in the chemistry of oxidative stress: A review
Diabetes alters the expression and translocation of the insulin-sensitive glucose transporters 4 and 8 in the atria
PRECLINICAL STUDIES ON PTEROSTILBENE FOR DIABETIC CARDIOMYOPATHY
Vascular function and structure in the rat aorta
Diabetes mellitus type 2 and proteinuria
Assessing the functional properties of high-density lipoproteins: an emerging concept in cardiovascular research
Amyloids of multiple species: are they helpful in survival?
Cardiovascular Risk Assessment in Diabetes and Chronic Kidney Diseases: A New Insight and Emerging Strategies
Aorto-Coronary Haemodynamics: Studies in Cardiovascular Magnetic Resonance
Peptides as potential therapeutics for Alzheimer’s disease
IMMUNOPATHOGENETIC AND PHARMACOLOGICAL ASPECTS OF INTERSTITIAL LUNG DISEASES
Studies on antibodies that form immune complexes with lipoprotein (a)[Lp (a)] in plasma
Expression and function of cellular prion protein in blood cells
Irbesartan ameliorates diabetic cardiomyopathy by regulating protein kinase D and ER stress activation in a type 2 diabetes rat model
Autoxidation of Plasma Lipids, Generation of Bioactive Products, and Their Biological Relevance
Histochemistry and cell biology: the annual review 2010
Stressful signaling: A role for endoplasmic retuculum stress in aortic stiffening during hypertension
AGING and Cardiovascular Risk
Immunomodulatory effects of human adipose derived stem cells on human macrophages in diabetic environment
Antioxidant-based therapies for angiotensin II-associated cardiovascular diseases
Mammalian thioredoxin reductase 1 in antioxidant defense, regulation of adipocyte differentiation and as an anticancer drug target
Reactive carbonyl species and their roles in sarcoplasmic reticulum Ca2+ cycling defect in the diabetic heart
Virulence factors of Clostridium difficile and their role during infection
The Study of the Properties of Collagen Hydrogel and 3T3 Fibroblast Cells’ Behavior Within Collagen Hydrogel by Multiphoton Microscopy (MPM)
Protective effects of desacyl ghrelin on doxorubicin-induced and diabetic cardiomyopathy
Delivery of nanoformulated superoxide dismutase to the brain for the treatment of angiotensin II-mediated hypertension
Cardiology Research and Practice
Micropatterns for Surface Potential Mapping of Biomolecules by Kelvin Probe Force Microscopy
Health Library
Mechanisms of Methylglyoxal-elicited Leukocyte Recruitment
PREMISES FOR THE THERAPEUTIC USE OF SELENIUM NANOPARTICLES IN OXIDATIVE STRESS-ASSOCIATED DISEASES
Amyloid fibril based bionanotechnologies.
The amyloid beta peptide: a chemist’s perspective. Role in Alzheimer’s and fibrillization
Myocardial metabolism in diabetic cardiomyopathy: potential therapeutic targets
Biomaterials: a systems approach to engineering concepts
PASPCR
Overview of antibody drug delivery
The effect of curcumin on cardiovascular health in obese men
Ph. D in Engineering of Materials and Structures XXV Cycle
Methodological approaches and insights on protein aggregation in biological systems
Animal Models of Myocardial Disease
Aptamer-based biosensors for biomedical diagnostics
A PROANGIOGENIC STRATEGY TO PROMOTE DIABETIC WOUND CLOSURE
A proangiogenic strategy to promote diabetic wound closure
IgG pharmacokinetics in a rat model of type 2 diabetes mellitus and diabetic nephropathy
Study to Correlate HBA1c and Left Ventricular Diastolic Dysfunction in Newly Diagnosed Type II Diabetes Mellitus
Ventricular-vascular Coupling and Central Arterial Pulse Pressure
Kidney disease in diabetes
Mechanism of 12/15 Lipoxygenase-induced Retinal Microvascular Dysfunction in Diabetic Retinopathy
The effect of topical therapies on ulcer healing and the wound micro-environment in diabetes mellitus
The HSP47-Procollagen Interaction: Mechanism of pH-Dependent Client Release and Development of Antifibrotic Inhibitors
Helix 8 plays a crucial role in bradykinin B2 receptor trafficking and signaling
Renal mitochondrial response to low temperature in non-hibernating and hibernating species
Beneficial effects of co-administration of PPAR-γ agonist with melatonin on cardiovascular complications associated with diabetes.
The anti-cancer effect of polyphenols against breast cancer and cancer stem cells: molecular mechanisms
Functional nucleic acids as molecular recognition elements for small organic and biological molecules
The Effect of Submerged Culture Mycelium of Higher Basidiomycetes Medicinal Mushrooms Agaricus Brasiliensis and Ganoderma Lucidum on …
Generation and characterization of RNA aptamer againtrHuEPO-α by SELEX technology
CD59a–A novel role in bone
Carnosine and cognitive deficits
Evidence for a Reversible, Redox-Mediated Component to Eccentric Contraction-Induced Force Loss in Dystrophin-Deficient Skeletal Muscle
Animal Models for the Study of Human Disease: Chapter 7. Animal Models of Myocardial Disease
From sequence to structure: determinants of functional and non-functional. Protein aggregation
Tomato proteomics: tomato as a model for crop proteomics
Oxidative Stress and Friedreich’s Ataxia
Neuroprotective properties of curcumin in Alzheimer’s disease-merits and limitations
A DFT study on the complexation of metal cations by the protein α-synuclein
Interventional Study of Low-magnitude High Frequency Vibration on the Healing of Foot Wound in Streptozotocin-induced Diabetic Rat Model
Left ventricular diastolic dysfunction in a community of African ancestry
Antioxidant capacity determination in plants and plant-derived products: A review
Investigation on key molecular targets responsible for antidiabetic properties of Symplocos Cochin Chinensis (Lour.) S. Moor
Gene Regulatory Networks: Modeling, Intervention and Context
Probing Early Stage Aggregates of Amyloidogenic Proteins using Mass Spectrometry Based Methods
Transforming the blood glucose meter into a general healthcare meter for in vitro diagnostics in mobile health
Oligomerisation-Aggregation and Fragmentation of Synuclein Polypeptides Revealed by Mass Spectrometry
Detection of Sap2 in the secretome of Candida albicans cell wall and secretory mutants
Proteomics in food science: From farm to fork
Biochemical basis for functional ingredient design from fruits
Molecular characterization of fruit-specific class III peroxidase genes in tomato (Solanum lycopersicum)
Composition, properties and nutritional aspects of milk fat globule membrane-a review
NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108 (5): 2052-2057, 2011 UMCG Afdeling: ANE CEL FAR MMB RKI Ref. ID: 542 …
Engineering Microdevices for Global Health Diagnostics
Vitamins B1, B2, B3 and B9–occurrence, biosynthesis pathways and functions in human nutrition
HIV, Immune activation and Endothelial Damage in Malawian Adults
Discovery and Mechanisms of Small Molecule Amyloid Formation Inhibitors
Aneurysm: New Insights for the Healthcare Professional: 2013 Edition
BRICHOS
Targeted nanoparticles for the treatment of Alzheimer’s disease
Interaction-mediating sequences within Class I viral fusion glycoproteins: their roles in viral infection and in applications
Peroxidase Catalyzed Degradation of Partially Hydrolyzed Polyacrylamide
Development of therapeutic systems to treat the infarcted heart
Intracellular Trafficking Governs the Processing of the Amyloid Precursor Protein and the Secretion of Beta-Amyloid
Efrosini Artikis1, Charles L. Brooks III1, 2 1Biophysics Program, University of Michigan, 930 North University, 2Department of Chemistry, Univer-sity of Michigan, 930 …
Structure and composition of the sorghum grain
Molecular basis of prion pathogenesis and development of a novel therapeutic strategy
Butylglyceryl-modified Polysaccharide Nanoparticles for Drug Delivery to the Brain
Impact of the environmental conditions and substrate pre-treatment on whey protein hydrolysis: A review
Neuroprotective effects of amantadine–flavonoid conjugates
4–8 December, 201 Cancuīn, Meīxico
Organized by ISEV and ISEV-Americas
Overview of polyphenols and their properties
Psychosocial and Oxidative Stress and Health of Adults
A comparative portrait of retroviral fusogens and syncytins
Development of New Tools for the Synthesis of” difficult Peptides”
Investigations into Structure Formation of Dairy Products
Chemical protein synthesis to study structure and function of amyloid fibers
HISTORY OF PIGMENT CELL RESEARCH IN EUROPE
A Novel Approach To Accommodative Human Intraocular Lenses
Process chromatography: a guide to validation
The identification and validation of GRIN2D as a novel endothelial target in colorectal cancer, and the investigation of its effects as a therapeutic tumour vaccine
Polyphenols: properties, recovery, and applications
Identification of beta-amyloid fibrillogenesis modulators as pharmacological tools in Alzheimer’s disease: an integrated approach
Production of recombinant Immunoglobulin A in plants for passive immunotherapy.
Biosensor evaluation of the antioxidant activity of wines and teas. Interference studies and comparison with other
Biosensor evaluation of the antioxidant activity of wines and teas. Interference studies and comparison with other methods
Spider silk: understanding the structure–function relationship of a natural fiber
Nutritional composition, antioxidant activity and bioaccessibility of phenolic compounds in selected wild cereal and pseudo-cereal grains found in Zimbabwe
Dengue virus type 3 in Malaysia: Diversity, origin, and spread/Tan Kim Kee
BIOSENSOR EVALUATION OF THE ANTIOXIDANT ACTIVITY OF WINES AND TEAS. INTERFERENCE STUDIES AND COMPARISON WITH OTHER …
Graduate Option in Biochemistry and Molecular Biophysics, Caltech 277. Computational design of a novel aldolase Jessica Mao, Stephen L. Mayo Designed …
Assessment of structural properties of amyloid aggregates and their application potential
Halanaerobium congolense: A Transplanted Microbe that Dominates Hydraulically Fractured Well Microbial Communities
Founder virus envelope glycoproteins as novel oligomeric HIV-1 vaccine immunogens
Influenza virus hemagglutinin contains a cholesterol consensus motif required for efficient intracellular transport and lipid raft integration
RNA Secondary Structure Inference and Functionalized Virus-Like Particles for Tumor Cell Detection and Enumeration
Textbook of structural biology
Defining the in vivo effects of divalent manganese in Caenorhabditis elegans
10. Large-Scale Mammalian Cell Culture Technology, edited by Anthony
Nucleic acids: function and potential for abiogenesis
From bee venom to blood-brain barrier shuttles. Development of minimized apamin derivatives for brain delivery of antibodies and other cargoes
Enzymes in non-conventional media
Long non-coding RNA antisense to Uchl1 increases its protein translation and identifies a new class of protein translation activators
Integrated atomic force microscopy techniques for analysis of biomaterials: Study of membrane proteins
Is It Time to Abandon Darwin?
Aptamer sensors for live-cell imAGING of Pol II promoter activity
Modeling The 3-Dimensional Structure Of D (Cgcgaattcgcg) And Its 8-Oxo-Da5 Adduct With 1H Nmr Noesy Refinements
Nano-fabrication of Accommodative Intraocular Lenses Using Gray-scale Electron Beam and Soft Lithography
Department of Biology Biotechnology Program
Designed and Evolved Nucleic Acid Nanotechnology
STUDY OF CHEMICAL AND MOLECULAR INFORMATION RELATED TO NIR AND IR SPECTROSCOPIC DATA FOR DAIRY SECTOR
Aggregation of alpha-synuclein using single-molecule spectroscopy
Chimera Ligand for Pili and Lectin A Protein Controls Antibiotic-Promoted Biofilm Formation, Swarming Motility, Tolerance and Persister Formation by Pseudomonas …
PARMA. A full text search based method for matching non-patent literature citations with scientific reference databases. A pilot study.
Theoretical studies of apolipoprotein interactions
Oxidation of Marine Oils during In Vitro Gastrointestinal Digestion and Its Effects on Stress in Human Intestinal Caco-2 Cells
Principal components of buffalo and cow milk from Bangladesh: Proteolysis and lipolysis of buffalo, cow and omega-3 enriched milk by ex vivo digestion
Construction and Characterization of Genomically Recoded Organisms and Synthetic Auxotrophs
Simulation Studies of Signaling and Regulatory Proteins
Reprint of “The complex dynamics of myocardial interstitial fibrosis in heart failure. Focus on collagen cross-linking”
Advanced GLYCATION End Products Are Retained in Decellularized Muscle MATRIX Derived from Aged Skeletal Muscle
Effect of Defatted Torreya nucifera Seed Extract on the Cross-linking of Advanced GLYCATION End Products to Collagen
Corneal stiffness and collagen cross-linking proteins in glaucoma: Potential for novel therapeutic strategy
GLYCATION-induced modification of tissue-specific ECM proteins: A pathophysiological mechanism in degenerative diseases
Alagebrium and complications of diabetes mellitus
Tumor necrosis factor Alpha-mediated inflammation and remodeling of the EXTRACELLULAR MATRIX underlies aortic stiffening induced by the common chemotherapeutic …
Collagen CROSSLINKING: effect on structure, mechanics and fibrosis progression
Stochastic non-enzymatic modification of long-lived macromolecules-A missing hallmark of AGING
Clinical/translational aspects of advanced GLYCATION end-products
More than genes and cells: Drug discovery in the EXTRACELLULAR MATRIX (ECM)
Too sweet: Problems of protein GLYCATION in the eye
Cross your heart? Collagen cross-links in cardiac health and disease
GLYCATION-induced protein aggregation and cellular toxicity: an insight into the disease realm of high dietary sugar intake
The role of inflammAGING and advanced GLYCATION end products on paratonia in patients with dementia
Effect of tetrahydrocurcumin analysis of fluorescence of collagenin experimental diabetes
The Putative Role of Methylglyoxal in Arterial Stiffening: A Review
Effect of advanced GLYCATION end‐products (AGE) lowering drug ALT‐711 on biochemical, vascular, and bone parameters in a rat model of CKD‐MBD
The impact of diabetic conditions and AGE/RAGE signaling on cardiac fibroblast migration
Advanced GLYCATION end products: A potential contributor of oxidative stress for cardio-vascular problems in diabetes
Inhibitors of Advanced GLYCATION End Product (AGE) Formation and Accumulation
Advanced GLYCATION end products: potential mechanism and therapeutic target in cardiovascular complications under diabetes
Deterioration of Glutaraldehyde Crosslinked Heterograft Biomaterials due to Advanced GLYCATION End Product Formation and Serum Albumin Infiltration
Advanced GLYCATION end-products, measured as skin autofluorescence, associate with vascular stiffness in diabetic, pre-diabetic and normoglycemic …
MATRIX metalloproteinase-9-dependent mechanisms of reduced contractility and increased stiffness in the AGING heart
Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With AGING in Mice and Humans
Development and progression of non-alcoholic fatty liver disease: The role of advanced GLYCATION end products
Therapeutic potential of vitamin D in AGE/RAGE-related cardiovascular diseases
Advanced GLYCATION end products (AGEs), receptor for AGEs, diabetes, and bone: review of the literature
A review on prevention of GLYCATION of proteins: Potential therapeutic substances to mitigate the severity of diabetes complications
Inhibitory effect and cross-link breaking activity of Moringa oleifera leaf crude extracts on fructose-derived advanced GLYCATION end-products
Mechanical characterization of native and sugar-modified decellularized kidneys
A review on mechanism of inhibition of advanced GLYCATION end products formation by plant derived polyphenolic compounds
Advanced GLYCATION end products (AGEs) may be a striking link between modern diet and health
Are Finger Skin Fluorophores Other Than Advanced GLYCATION End Products (AGEs) Associated With Impaired Musculoskeletal Properties?
Model studies of advanced GLYCATION end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen …
Large artery stiffness and brain health: Insights from animal models
Role of changes in state of bound water and tissue stiffness in development of age-related diseases
Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice
Mechanosensing dysregulation in the fibroblast: a hallmark of the AGING heart
Anti-AGING effects of Muntingia calabura leaves extract in D-galactose-induced skin AGING mouse model
Flavonoids derived from buckwheat hull can break advanced GLYCATION end-products and improve diabetic nephropathy
The impact of advanced GLYCATION end products on bone properties in chronic kidney disease
Arterial stiffness: a focus on vascular calcification and its link to bone mineralization
The melibiose-derived GLYCATION product mimics a unique epitope present in human and animal tissues
The collagen suprafamily: from biosynthesis to advanced biomaterial development
Advanced GLYCATION End Products: Origins and Role in AGING
Diabetic fibrosis
Rise and fall of elastic fibers from development to AGING. Consequences on arterial structure-function and therapeutical perspectives
GLYCATION and antioxidants: hand in the glove of antiGLYCATION and natural antioxidants
AGE/Non-AGE GLYCATION: An Important Event in Rheumatoid Arthritis Pathophysiology
Cellular and molecular differences between HFpEF and HFrEF: a step ahead in an improved pathological understanding
Clinical complications of tendon tissue mechanics due to collagen cross-linking in diabetes
Constitutive interpretation of arterial stiffness in clinical studies: a methodological review
Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications, and other age-related diseases
AGE/RAGE in diabetic kidney disease and ageing kidney
Advanced GLYCATION endproducts and bone quality: practical implications for people with type 2 diabetes
GLYCATION and Glycosylation in Cardiovascular Remodeling: Focus on Advanced GLYCATION End Products and O-Linked Glycosylations as Glucose-Related …
… of Maillard reaction, and Advanced GLYCATION End Product (AGE)-Receptor for AGE (RAGE) signaling inhibitors as novel therapeutic strategies for patients with age …
The multifunctional roles of flavonoids against the formation of advanced GLYCATION end products (AGEs) and AGEs-induced harmful effects
Serum 25-hydroxyvitamin D3 is associated with advanced GLYCATION end products (AGEs) measured as skin autofluorescence: The Rotterdam Study
Engineered cardiac tissues: a novel in vitro model to investigate the pathophysiology of mouse diabetic cardiomyopathy
Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities
Hypoglycemic Drugs and Advanced GLYCATION End products
Role of advanced GLYCATION end products (AGEs) and its receptor (RAGE)-mediated diabetic vascular complications
Soluble receptor for advanced GLYCATION end-products independently influences individual age-dependent increase of arterial stiffness
GLYCATION and serum albumin infiltration contribute to the structural degeneration of bioprosthetic heart valves
Cardiac tissue remodeling in healthy AGING: the road to pathology
Role of Amino Acids on Prevention of Lens Proteins Nonenzymatic GLYCATION In Vitro, in Senile, and Diabetic Cataract
Central artery stiffness and thoracic aortopathy
Of mice and men: models and mechanisms of diabetic cardiomyopathy
Tendon EXTRACELLULAR MATRIX Assembly, Maintenance and Dysregulation Throughout Life
Advanced GLYCATION End Products: New Clinical and Molecular Perspectives
Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor?
A novel treatment for heart failure targets myocardial fibrosis
The Gut-Arterial Stiffness Axis: Is TMAO a Novel Target to Prevent Age-Related Aortic Stiffening?
Book Chapter The Receptor for Advanced GLYCATION End Products (RAGE): A Potential Target for Therapeutic Intervention in the Progression of Non-Alcoholic …
Interleukin-10 protects schwann cells against advanced GLYCATION end products-induced apoptosis via NF-κB suppression
Uremic toxin–targeting as a therapeutic strategy for preventing cardiorenal syndrome
Concerns about clinical efficacy and safety of warfarin in diabetic patients with atrial fibrillation
Fibrosis in chronic kidney disease: Pathogenesis and consequences
Fibrosis of the diabetic heart: clinical significance, molecular mechanisms, and therapeutic opportunities
Ryanodine receptor GLYCATION favors mitochondrial damage in the senescent heart
In Vitro and In Vivo AntiGLYCATION Effects of Connarus ruber Extract
Advanced GLYCATION end products and their receptors in serum of patients with type 2 diabetes
Endothelial dysfunction: a contributor to adverse cardiovascular remodeling and heart failure development in type 2 diabetes beyond accelerated atherogenesis
L-carnosine and its Derivatives as New Therapeutic Agents for the Prevention and Treatment of Vascular Complications of Diabetes
The diabetic cardiomyopathy: The contributing pathophysiological mechanisms
The relevance of toxic AGEs (TAGE) cytotoxicity to NASH pathogenesis: A mini-review
D-ribose induces podocyte NLRP3 inflammasome activation and glomerular injury via AGEs/RAGE pathway
Natural Products as a Source of Inspiration for Novel Inhibitors of Advanced GLYCATION Endproducts (AGEs) Formation
Chronic kidney disease as a risk factor for heart failure with preserved ejection fraction: a focus on microcirculatory factors and therapeutic targets
Role of advanced GLYCATION end products and insulin resistance in diabetic nephropathy
An Electrochemical Chip to Monitor In Vitro GLYCATION of Proteins and Screening of AntiGLYCATION Potential of Drugs
Linking LOXL2 to Cardiac Interstitial Fibrosis
Advanced GLYCATION End-Products (AGEs) and Their Soluble Receptor (sRAGE) in Women Suffering from Systemic Lupus Erythematosus (SLE)
AGE/RAGE signaling-mediated endoplasmic reticulum stress and future prospects in non-coding RNA therapeutics for diabetic nephropathy
Skin Autofluorescence, a Noninvasive Biomarker for Advanced GLYCATION End‐Products, Is Associated With Prevalent Vertebral and Major Osteoporotic Fractures: The …
Role of the lysyl oxidase enzyme family in cardiac function and disease
Advanced GLYCATION End Products Are Associated With Inflammation and Endothelial Dysfunction in HIV
Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications
Nitroxidized-Albumin Advanced GLYCATION End Product and Rheumatoid Arthritis
Poor bone MATRIX quality: What can be done about it?
The Potential Role of Gene Editing in the AGING of Somatic cells: A Review of Literature
Arterial stiffness as a measure of vascular dysfunction in hypertensive women
Therapeutic potential of Nigella sativa in the prevention of aggregation and GLYCATION of proteins
Arterial stiffness and cardiovascular risk in hypertension
Left ventricular dysfunction in heart failure with preserved ejection fraction—molecular mechanisms and impact on right ventricular function
The AGE receptor, OST48 drives podocyte foot process effacement and basement
Pathological role of advanced GLYCATION end products (AGEs) and their receptor axis in atrial fibrillation
Advanced GLYCATION end products and risks for chronic diseases: intervening through lifestyle modification
Trapa bispinosa Roxb. extract lowers advanced GLYCATION end-products and increases live births in older patients with assisted reproductive technology: a …
Intramyocardial injections to de-stiffen the heart: A subject-specific in silico approach
The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion in experimental diabetic kidney disease via promotion of …
Circulating advanced GLYCATION endproducts and long-term risk of cardiovascular mortality in kidney transplant recipients
Established and emerging mechanisms of diabetic cardiomyopathy
Skin autofluorescence is associated with progression of kidney disease in type 2 diabetes: A prospective cohort study from the Hong Kong diabetes biobank
Phytochemicals against anti‐diabetic complications: targeting the advanced GLYCATION end product signaling pathway
The Impact of Advanced GLYCATION End-Products (AGEs) on Proliferation and Apoptosis of Primary Stem Cells: A Systematic Review
Effect of antidiabetic drugs on the risk of atrial fibrillation: mechanistic insights from clinical evidence and translational studies
Prevention of vascular complications in diabetes mellitus patients: focus on the arterial wall
Collagen peptide simulated bending after applied axial deformation
Absolute configuration of mycosporine-like amino acids, their wound healing properties and in vitro anti-AGING effects
Arterial Stiffness as a Measure of Vascular Dysfunction in Hypertensive Women
Dysregulated Protein Homeostasis in the AGING Organism
Effect of Citrullus colocynthis extract on glycated hemoglobin formation (In vitro)
Arterial stiffness in the heart disease of CKD
Casein Hydrolysate Containing Milk-Derived Peptides Reduces Facial Pigmentation Partly by Decreasing Advanced GLYCATION End Products in the Skin: A …
Natural products as potential inhibitors of Advanced GLYCATION Endproducts (AGEs) and modulators of autophagy
AGEs-related dysfunctions in PCOS: evidence from animal and clinical research
Induction and rescue of skeletal fragility in a high-fat diet mouse model of type 2 diabetes: An in vivo and in vitro approach
Advanced GLYCATION End Products
Glycolaldehyde-derived high-molecular-weight advanced GLYCATION end-products induce cardiac dysfunction through structural and functional remodeling of …
The association of non-invasive skin autofluorescence measurements with cardiovascular and all-cause mortality in hemodialysis patients: a meta-analysis
Arterial stiffness and hypertension in the elderly
Diabetes and Pancreatic Cancer—A Dangerous Liaison Relying on Carbonyl Stress
Glucose and Blood Pressure-Dependent Pathways–The Progression of Diabetic Kidney Disease
Effect of Advanced GLYCATION End-Products and Excessive Calorie Intake on Diet-Induced Chronic Low-Grade Inflammation Biomarkers in Murine Models
Microalbuminuria
Carbamylated Proteins in Renal Disease: Aggravating Factors or Just Biomarkers?
Alagebrium and spironolactone ameliorate dietary induced metabolic syndrome in male Wister rats
Glyoxalase 1 modulation in obesity and diabetes
Physical activity and markers of GLYCATION in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE)
Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model
Protective effect of vanillin on diabetic nephropathy by decreasing advanced GLYCATION end products in rats
Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19—The Role of RAGE-RAS Crosstalk
Polyphenols and AGEs/RAGE axis. Trends and challenges
Novel advances in inhibiting advanced GLYCATION end product formation using natural compounds
Diabetes, Incretin Therapy and Thoracic Aortic Aneurysm–What Does the Evidence Show?
The physical microenvironment of tumors: characterization and clinical impact
Soluble RAGEs and cardiovascular risk factors in adult offspring of patients with premature coronary heart disease
Switching dipeptidyl peptidase-4 inhibitors to tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2 improve arterial stiffness evaluated by cardio-ankle …
Biomarkers of inflammation in left ventricular diastolic dysfunction
AGING of the Retina: Molecular and Metabolic Turbulences and Potential Interventions
Translational applications of glucose metabolism in abdominal aortic aneurysm
Basic mechanisms of diabetic heart disease
The importance of mechanical forces for in vitro endothelial cell biology
Inhibition of the receptor for advanced GLYCATION end-products in acute respiratory distress syndrome: a randomised laboratory trial in piglets
Role of GLYCATION in Type 2 Diabetes Mellitus and Its Prevention through Nymphaea Species
Treating Arterial Ageing in Patients with Diabetes: From Mechanisms to Effective Drugs
Why and how do we age? A single answer to two questions
Novel paradigms in the therapeutic management of heart failure with preserved ejection fraction: clinical perspectives
Perivascular drainage of amyloid beta (Aβ) and waste products from the brain and its failure.
Cross linkage between oxidative stresses in diabetic nephropathy: An updated review
Advanced GLYCATION End Products in Meat during Processing and Storage: A Review
Biocatalytic Transformation of AGING-Associated Metabolites
Arterial de-stiffing Drugs: Which Promising Therapeutic Agent is Useful?
Molecular Signature of HFpEF: Systems Biology in a Cardiac-Centric Large Animal Model
The diabetic cardiac fibroblast: mechanisms underlying phenotype and function
Metabolic syndrome and its components predict the development of arterial stiffening in a sample of adult men
Peroxidasin promotes diabetic vascular endothelial dysfunction induced by advanced GLYCATION end products via NOX2/HOCl/Akt/eNOS pathway
Macrovasculature and microvasculature at the crossroads between type 2 diabetes mellitus and hypertension
Novel dietary factors in diabetic and non-diabetic kidney disease
As time flies by: investigating cardiac AGING in the short-lived Drosophila model
Molecular characteristics of RAGE and advances in small-molecule inhibitors
Potential role of metal chelation to prevent the cardiovascular complications of diabetes
A STUDY OF PLASMA GLUCOSE AND SERUM CERULOPLASMIN IN TYPE-2 DIABETES MELLITUS (T2DM) AT A TERTIARY CARE HOSPITAL
Synthesis, characterization and detection of novel protein modifications in vitro and in vivo:[kumulative Dissertation]
Lipoxidation in cardiovascular diseases
Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future
Salvia miltiorrhiza prevents methylglyoxal-induced glucotoxicity via the regulation of apoptosis-related pathways and the glyoxalase system in human umbilical vein …
Improvement in diabetic retinopathy through protection against retinal apoptosis in spontaneously diabetic torii rats mediated by ethanol extract of Osteomeles …
Advanced GLYCATION end products (AGEs)
Diabetes as a risk factor for periodontal disease—plausible mechanisms
Heart failure in type 2 diabetes mellitus: impact of glucose-lowering agents, heart failure therapies, and novel therapeutic strategies
Effect of Advanced GLYCATION End Products on Regulation of Placental Growth Factor
Advanced GLYCATION End Products and Oxidative Stress in a Hyperglycaemic Environment
Myocardial Basis for Heart Failure: Role of Cardiac Interstitium
The role of inflammation and neurodegeneration in diabetic macular edema
Non-invasive measurements of arterial function: What? When? Why should we use them?
Type I Angiotensin II Receptor Blockade Reduces Uremia‐Induced Deterioration of Bone Material Properties
Skin autofluorescence is associated with rapid renal function decline in subjects at increased risk of coronary artery disease
Role of AMP-activated protein kinase on cardio-metabolic abnormalities in the development of diabetic cardiomyopathy: A molecular landscape
Diet-Derived Advanced GLYCATION End Products (dAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective …
Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin …
Therapeutic targets for the treatment of cardiac fibrosis and cancer: focusing on TGF-β signaling
Recent advances in Raman spectroscopy of proteins for disease diagnosis
8.1 EXTRACELLULAR MATRIX (ECM)
Targeting cardiac fibrosis in heart failure with preserved ejection fraction: mirage or miracle?
Pathogenesis of Diabetic Cardiomyopathy and role of miRNA
Left Ventricular Diastolic Function: an Early Sign of Cardiac Damage
Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle
Concurrent diabetes and heart failure: interplay and novel therapeutic approaches
Phenethyl isothiocyanate attenuates diabetic nephropathy via modulation of glycative/oxidative/inflammatory signaling in diabetic rats
Pathological perturbations in diabetic retinopathy: hyperglycemia, AGEs, oxidative stress and inflammatory pathways
Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells
Recent advances and the potential for clinical use of autofluorescence detection of extra-ophthalmic tissues
A unifying model of glucotoxicity in human renal proximal tubular epithelial cells and the effect of the SGLT2 inhibitor dapagliflozin
Alagebrium targets the miR-27b/TSP-1 signaling pathway to rescue Nε-carboxymethyl-lysine-induced endothelial dysfunction
Application of Animal Models in Diabetic Cardiomyopathy
A concise appraisal of lipid oxidation and lipoxidation in higher plants
Novel treatments for diastolic heart failure
Heart failure with preserved ejection fraction based on AGING and comorbidities
Swertiamarin mitigates nephropathy in high-fat diet/streptozotocin-induced diabetic rats by inhibiting the formation of advanced GLYCATION end products
Sirtuins: To Be or Not To Be in Diabetic Cardiomyopathy
The efficacy of dry beans (Phaseolus vulgaris L.) for improving vascular function: exploring seed coat colour as an indicator of functionality
LOX and LOX-Like Proteins as Potential Therapeutic Target for Atrial Fibrillation
Advances in research on the bioactivity of alginate oligosaccharides
Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs
Biomarkers of osteoporosis: an update
Bone quality analysis of jaw bones in individuals with type 2 diabetes mellitus—post mortem anatomical and microstructural evaluation
Pathogenesis of Microvascular Complications
The biological basis of AGING: implications for medical genetics
Regulation of Coronary Blood Flow in Normal and Ischemic States: Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular …
Potential of Vasoprotectives to Inhibit Non-Enzymatic Protein GLYCATION, and Reactive Carbonyl and Oxygen Species Uptake
Investigating aberrant DNA methylation patterns in LOXL2 as a potential predictor of diabetes-induced cardiac dysfunction
Aortic Stiffness: Review of Life Course, Epidemiology, Risk Factors, and Relevant Biomarkers
Nanomedicine for the treatment of diabetes-associated cardiovascular diseases and fibrosis
Diabetes and Cognitive Impairment
Arterial stiffness–A measurable vascular marker in clinical practice
Potential therapeutic value of melatonin in diabetic nephropathy: improvement beyond anti-oxidative stress
Lipopeptides in promoting signals at surface/interface of micelles: Their roles in repairing cellular and nuclear damages
The Mystery of Diabetic Cardiomyopathy: From Early Concepts and Underlying Mechanisms to Novel Therapeutic Possibilities
Dietary N‐epsilon‐carboxymethyllysine as for a major glycotoxin in foods: A review
WOMEN IN REPRODUCTIVE SCIENCE: My WOMBan’s life: understanding human endometrial function
Reduction of renal tubular injury with a RAGE inhibitor FPS-ZM1, valsartan and their combination in streptozotocin-induced diabetes in the rat
Pyrazolotriazines: biological activities, synthetic strategies and recent developments
The impact of dietary choline-deprivation on kidneys and heart of stz-induced diabetic rats
CHAPTER NUMBER CHAPTER NAME PAGE
Differential Gene Transcription in Monocytes from Chronic Kidney Disease and Healthy Patients
Reducing PD-L1 expression with a self-assembled nanodrug: an alternative to PD-L1 antibody for enhanced chemo-immunotherapy
Activation of general control nonderepressible-2 kinase ameliorates glucotoxicity in human peritoneal mesothelial cells, preserves their integrity, and prevents …
Functionalised Flouroquinolones as a Potentially Novel Class of Anti-inflammatory and Anti-GLYCATION Compounds; Synthesis and Pharmacological Appraisal
Cardiovascular changes with AGING
Conditioning Medicine
SIRT1-dependent upregulation of antiglycative defense in HUVECs is essential for resveratrol protection against high glucose stress
Diabetes and hypertension differentially affect renal catecholamines and renal reactive oxygen species
Atomic Force Microscopy-based essay for biomedical applications
A Study to Evaluate the Associated Systemic Risk Factors in Type 2 Diabetes Mellitus patients with Clinically Significant Macular Edema
A clinical primer for the glymphatic system
Syntheses, characterization, in vitro antiGLYCATION and DPPH radical scavenging activities of isatin salicylhydrazidehydrazone and its Mn (II), Co (II), Ni (II), Cu …
Understanding collagen interactions and their targeted regulation by novel drugs
Insulin Treatment Reduces Susceptibility to Atrial Fibrillation in Type 1 Diabetic Mice
The effects of diet and gut microbiota on the regulation of intestinal mucin glycosylation
Impact of diabetes on cardiac and vascular disease: Role of calcium signaling
A concise appraisal of lipid oxidation and lipoxidation in higher plants
Oxidative Stress, Ageing and Methods of Seed Invigoration: An Overview and Perspectives
Intestinal microbiota and diabetic kidney diseases: role of microbiota and derived metabolites in the modulation of renal inflammation and disease …
Speckle-Tracking Echocardiography is Preferable Measurement for Detecting the Early and Subtle Alterations of Cardiac Dysfunction in Diabetic Rats
Peptidome and Proteome Peritoneal Dialysate Evolutionary Atlas (P3DEVOATLAS)
3, 4-dehydro-L-proline Induces Programmed Cell Death in the Roots of Brachypodium distachyon
Expression profiling and recombinant production of TomEP, a Tomato Extensin Peroxidase
Factors affecting thermal stability of collagen from the aspects of extraction, processing and modification
Examining SERCA2a acetylation in the diseased human heart
Mucolytic bacteria: prevalence in various pathological diseases
Musculoskeletal disorders associated with diabetes
Development of health products from natural sources
Solubility of extracted proteins from Chlorella sorokiniana, Phaeodactylum tricornutum, and Nannochloropsis oceanica: Impact of pH-value
Preliminary evidence for the presence of multiple forms of cell death in diabetes cardiomyopathy
The Role of FCGBP in Mucus-Structure, Processing and Function
Introduction to Peptide Science
Bibliography Current World Literature Vol 15 No 2 March 2006
Nanobiotechnology in neurodegenerative diseases
ANTIOXIDANT CAPACITIES AND BIOACTIVE COMPOUNDS OF NOVEL THERMO-TOLERANT GREEN MICROALGAE
Discovering inhibitors of cell surface receptor function as the basis for novel therapeutics to treat cancer
Value-a ddedUsesofEggshell andEggshellMembranes
On the Mechanobiology of Collagen Growth and Remodelling
Processing and Presentation of Hybrid Polypeptides in Type 1 Diabetes
Understanding the Structure, Toxicity and Inhibition of IAPP at the Nanoscale
Bibliography Current World Literature Vol 14 No 5 September 2005
Fluorescent diagnostic probes in neurodegenerative diseases
Pharmacological management of vascular endothelial dysfunction in diabetes: TCM and western medicine compared based on biomarkers and biochemical …
Development of oligomer-specific antibodies against tau protein and testing of therapeutic potential in a cell model of tau pathology
Receptor specific, stimuli responsive and subcellular targeted approaches for effective therapy of Alzheimer: Role of surface engineered nanocarriers
Nanoparticle-Guided Brain Drug Delivery: Expanding the Therapeutic Approach to Neurodegenerative Diseases
Computational design and experimental validation of novel Self-Assembling Peptides
Investigation into multifunctional nanoparticles for the detection, imAGING and intervention of amyloid
Development of a Yeast Biosynthetic Platform for Rapid Production and Engineering of an Influenza Virus-like Particle Vaccine
Quantitative fluorescence microscopy techniques to study three-dimensional organisation of T-cell signalling molecules.
Identification of small molecules with reactivities against multiple pathogenic elements of alzheimer’s disease
Molecular Biology Gene to Proteins
Inorganic Nanoparticles and Their Strategies to Enhance Brain Drug Delivery
Novel Delivery Systems of Polyphenols and Their Potential Health Benefits
Antioxidant and AntiGLYCATION Properties of Fifteen Cultivated and Wild Vigna Species
Advanced Fermentation and Cell Technology, 2 Volume Set
Photochromic ligands for in vivo modulation of adrenergic neurotrasmission
Microencapsulation of Thunbergia lauriforlia crude extract and its antioxidant properties
Microencapsulation of Thunbergia laurifolia crude extract and its antioxidant properties
Synthetic macromolecules as therapeutics that overcome resistance in cancer and microbial infection
A holistic view on transcriptional regulatory networks in S. cerevisiae: Implications and utilization
Molecular mechanisms underlying Woodhouse-Sakati syndrome: characterization of DCAF17 with specific, polyclonal antibodies
Laccase-mediated biotransformation of phenolic compounds for the synthesis of new antioxidants
Review of the current state of protein aggregation inhibition from a materials chemistry perspective: special focus on polymeric materials
About TFE: Old and new findings
Present health challenges in fresh and processed meat
Single-molecule mechanics and regulatory conformational transitions of the force-sensing protein von Willebrand factor
The impact of wavelength in plant’s response to extreme light-induced stress
The Impact of Wavelength in Plant’s Response to Extreme Light-Induced Stress
The Role of GAGA Motif Domains in Chromatin Remodeling of Igκ during B Cell Development
M6A Reshapes the Folding and Recognition Landscape of RNAs
Combining Computational and Experimental Approaches to Study Disordered and Aggregation Prone Proteins
From Plants to Pores: Selection, Design, and Optimization of Antimicrobial Peptide Scaffolds from Putative Bacteriocins
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