Exercise has anti aging effects via:
1. Improved Mitochondrial Function: Exercise has been shown to improve mitochondrial function in skeletal muscle. Mitochondria are responsible for producing energy in cells, and their dysfunction is associated with aging. Exercise can increase the number and efficiency of mitochondria, leading to improved energy production and overall muscle function.
2. Increased Muscle Strength: Resistance exercise training can increase muscle strength in older adults. This improvement in strength is not only due to muscle hypertrophy (increase in muscle size) but also to improvements in neuromuscular coordination and activation. These adaptations can help reverse the age-related decline in muscle strength.
3. Enhanced Protein Synthesis: Exercise stimulates protein synthesis in skeletal muscle, leading to the production of new muscle proteins. This is important for muscle growth, repair, and maintenance. Aging is associated with a decline in protein synthesis, and exercise can help counteract this decline by promoting protein turnover and muscle protein synthesis.
4. Reduced Oxidative Stress: Aging is associated with increased oxidative stress, which can damage cells and contribute to muscle dysfunction. Exercise has been shown to reduce oxidative stress by increasing antioxidant enzyme activity and reducing markers of oxidative damage. This can help protect muscle cells from oxidative damage and improve overall muscle health.
5. Improved Gene Expression: Exercise can modulate gene expression in skeletal muscle, leading to changes in the expression of genes involved in muscle growth, metabolism, and inflammation. These changes in gene expression can help reverse the age-related alterations in the transcriptome profile of skeletal muscle, leading to a more youthful gene expression profile
Resistance exercise reverses aging in human skeletal muscle
Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.
Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.