Cytokines are tiny but mighty messengers in the body, acting as signal flares between cells, particularly those of the immune system. They play a critical role in both inflammation and pain. When tissues are injured or infected, immune cells release pro-inflammatory cytokines, triggering the classic signs of inflammation: redness, swelling, heat, and pain.These cytokines directly stimulate nerves, contributing to the pain sensation. However, cytokines are a double-edged sword. While they cause discomfort during inflammation, they also help heal and repair damaged tissue. The key lies in a balanced response.
This balance becomes disrupted with aging. A chronic, low-grade inflammatory state termed “inflammaging” sets in,fueled by an increase in pro-inflammatory cytokines. This disrupts normal tissue function and is linked to various age-related diseases like arthritis and Alzheimer’s. Research suggests that targeting cytokine activity could hold immense potential for promoting healthy aging and managing chronic pain and inflammation.
Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.
Mandatory FDA Disclaimer: Not intended to diagnose, treat, cure or prevent any disease.