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Cyp2e1

  1. Oxidative stress, toxicology, and pharmacology of CYP2E1
  2. Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity
  3. CYP2E1 and oxidative liver injury by alcohol
  4. Human CYP2E1 is regulated by miR-378
  5. Role of CYP2E1 in the Hepatotoxicity of Acetaminophen (∗)
  6. CYP2E1
  7. CYP2E1: from ash to nash
  8. Human hepatic CYP2E1 expression during development
  9. Ethanol Induces CYP2E1 by Protein Stabilization: ROLE OF UBIQUITIN CONJUGATION IN THE RAPID DEGRADATION OF CYP2E1 (∗)
  10. Role of CYP2E1 in Diethylnitrosamine-Induced Hepatocarcinogenesis In vivo
  11. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
  12. Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region
  13. Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
  14. The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity
  15. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
  16. Genetic polymorphism of human CYP2E1: characterization of two variant alleles
  17. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
  18. Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
  19. CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
  20. CYP2E1 and risk of chemically mediated cancers
  21. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
  22. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
  23. CYP2E1 mediated isoniazid-induced hepatotoxicity in rats
  24. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.
  25. CYP2E1 is not involved in early alcohol-induced liver injury
  26. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese.
  27. Detection and characterization of novel polymorphisms in the CYP2E1 gene.
  28. Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
  29. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury
  30. Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans.
  31. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
  32. Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone
  33. CYP2E1—biochemical and toxicological aspects and role in alcohol-induced liver injury
  34. CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
  35. Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period
  36. Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
  37. The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression
  38. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice
  39. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model
  40. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
  41. Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
  42. Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …
  43. Development and properties of HepG2 cells that constitutively express CYP2E1
  44. Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
  45. CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis
  46. Human CYP2E1 mediates the formation of glycidamide from acrylamide
  47. Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts
  48. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
  49. Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
  50. Iron and CYP2E1-dependent oxidative stress and toxicity
  51. Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
  52. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity
  53. Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
  54. Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
  55. CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
  56. In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
  57. CYP2E1-dependent toxicity and up-regulation of antioxidant genes
  58. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
  59. Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain
  60. Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
  61. Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
  62. Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
  63. Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective
  64. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
  65. Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
  66. Association of CYP2E1 gene polymorphism with predisposition to cancer development
  67. CYP2E1 substrate inhibition: Mechanistic interpretation through an effector site for monocyclic compounds
  68. Transcriptional control of the rat hepatic CYP2E1 gene
  69. Transcriptional control of CYP2E1 in the perivenous liver region and during starvation
  70. Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate
  71. Nrf2 and antioxidant defense against CYP2E1 toxicity
  72. Acetaldehyde as well as ethanol is metabolized by human CYP2E1
  73. NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis
  74. Associations of CYP1A1, GSTM1, and CYP2E1 Polymorphisms with Lung Cancer Suggest Cell Type Specificities to Tobacco Carcinogens
  75. Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization
  76. Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics
  77. Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity
  78. Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice
  79. Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.
  80. Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
  81. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
  82. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1
  83. CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells
  84. Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
  85. CYP2E1 activity in patients with alcoholic liver disease
  86. Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
  87. CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury
  88. Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats
  89. CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
  90. Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Cancer: The Fukuoka Colorectal Cancer Study
  91. Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients
  92. Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice
  93. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
  94. Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples
  95. CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase
  96. Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients
  97. Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population
  98. The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
  99. Ethanol induction of CYP2A5: permissive role for CYP2E1
  100. Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse
  101. Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
  102. Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
  103. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
  104. Red Meat Intake, CYP2E1 Genetic Polymorphisms, and Colorectal Cancer Risk
  105. Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
  106. Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
  107. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
  108. Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice
  109. Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
  110. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
  111. Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress
  112. Tissue-specific expression and methylation of the human CYP2E1 gene
  113. Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations.
  114. Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
  115. Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells
  116. Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population
  117. Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis
  118. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
  119. Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors
  120. The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population
  121. Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
  122. Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1
  123. Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability
  124. Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions
  125. Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1 …
  126. Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation
  127. Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …
  128. Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
  129. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
  130. Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole
  131. Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
  132. The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives
  133. The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis
  134. Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling
  135. Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations
  136. Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
  137. The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …
  138. Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
  139. Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression
  140. Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
  141. Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice
  142. Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
  143. The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
  144. Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene
  145. Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
  146. Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
  147. Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice
  148. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver
  149. The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
  150. Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
  151. Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
  152. Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?
  153. Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer
  154. Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
  155. Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
  156. … for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
  157. Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
  158. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China
  159. Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …
  160. Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
  161. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …
  162. Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order
  163. Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
  164. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1
  165. CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.
  166. NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review
  167. Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation
  168. An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)
  169. Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
  170. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
  171. Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation
  172. Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice
  173. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
  174. Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats
  175. CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
  176. St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
  177. Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes
  178. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine
  179. Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma
  180. Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues
  181. Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
  182. Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
  183. Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene
  184. A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
  185. CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
  186. Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
  187. Differential Modulation of CYP2E1 Activity by CAMP-Dependent Protein Kinase upon Ser129Replacement
  188. Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
  189. Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
  190. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations
  191. Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat
  192. Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)
  193. Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice
  194. CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
  195. Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
  196. Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
  197. Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.
  198. Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users
  199. Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A
  200. Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations
  201. CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus
  202. Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro
  203. Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
  204. Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
  205. Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
  206. Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …
  207. Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
  208. A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer …
  209. Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease
  210. CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro
  211. Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.
  212. Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver
  213. Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population
  214. Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes
  215. Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
  216. Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1
  217. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90
  218. CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …
  219. Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
  220. Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro
  221. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity
  222. Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma
  223. Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
  224. CYP2E1 expression in human lymphocytes from various ethnic populations
  225. Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
  226. CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …
  227. CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism
  228. The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
  229. Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population
  230. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
  231. Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans
  232. Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers
  233. Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer
  234. The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
  235. CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
  236. Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …
  237. DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1
  238. Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes
  239. Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …
  240. Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation
  241. Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
  242. The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney
  243. Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody
  244. Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition
  245. Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population
  246. Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments
  247. Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein
  248. Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population
  249. Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation
  250. CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
  251. The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures
  252. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats
  253. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
  254. CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism
  255. Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes
  256. Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …
  257. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
  258. Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians
  259. CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and …
  260. CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians
  261. The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
  262. Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
  263. A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …
  264. Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels
  265. Identification of CYP2E1 in marmoset monkey
  266. Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …
  267. Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?
  268. Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China
  269. ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects
  270. Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
  271. Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats
  272. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity
  273. Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
  274. Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung
  275. CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese
  276. Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity
  277. Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition
  278. Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1
  279. NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species
  280. Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors
  281. GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.
  282. Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
  283. A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate
  284. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1
  285. GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
  286. A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice
  287. Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats
  288. Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …
  289. Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice
  290. Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
  291. Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
  292. Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
  293. Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells
  294. Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai’an population, China
  295. Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
  296. Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
  297. Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver
  298. … exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …
  299. Relationship between alcoholism and CYP2E1 C/D polymorphism
  300. Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma
  301. Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells
  302. Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
  303. Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects
  304. Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells
  305. Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes
  306. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …
  307. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
  308. Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1
  309. Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years
  310. Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis
  311. A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations
  312. Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes
  313. Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
  314. Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese
  315. Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity
  316. Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney
  317. cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1
  318. … and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1
  319. CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis
  320. Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ
  321. Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
  322. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells
  323. Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1
  324. Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …
  325. The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver
  326. Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells
  327. Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1
  328. The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
  329. Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
  330. Impact of CYP2E1 genotype in renal cell and urothelial cancer patients
  331. Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage
  332. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1
  333. Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response
  334. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes
  335. Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration
  336. Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism
  337. Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.
  338. Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
  339. Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice
  340. Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
  341. Changes of CYP2E1 activity in diabetic rat model
  342. Use of molecular simulation for mapping conformational CYP2E1 epitopes
  343. Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion
  344. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
  345. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine
  346. Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
  347. CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …
  348. Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital
  349. Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing
  350. Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
  351. The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
  352. Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups
  353. Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—
  354. Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice
  355. … in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …
  356. Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects
  357. Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C
  358. CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice
  359. Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
  360. Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity
  361. Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
  362. Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
  363. Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity
  364. Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
  365. Functional CYP2E1 is required for substantial in vivo formation of 2, 5-hexanedione from n-hexane in the mouse
  366. Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A
  367. Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics
  368. … by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3
  369. Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans
  370. Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model
  371. Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells
  372. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1
  373. Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways
  374. DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …
  375. Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?
  376. XRCC1 and CYP2E1 Polymorphisms as Susceptibility Factors of Plasma Mutant p53 Protein and Anti-p53 Antibody Expression in Vinyl Chloride …
  377. Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood
  378. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
  379. CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers
  380. Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction
  381. Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide
  382. High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks
  383. Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
  384. Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …
  385. Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
  386. Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation
  387. Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality
  388. Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1
  389. The 2006 bernard B. Brodie award lecture: CYP2E1
  390. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
  391. Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers
  392. Genetic polymorphisms of CYP2E1 and GSTM1 in a Thai population
  393. DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1
  394. A comparison of substrate dynamics in human CYP2E1 and CYP2A6
  395. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice
  396. Expression of CYP2E1 by human monocyte‐derived macrophages
  397. CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians
  398. NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption
  399. Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway
  400. Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation
  401. Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology
  402. Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
  403. Insertion polymorphism of CYP2E1 and urinary N-methylformamide after N, N-dimethylformamide exposure in Japanese workers
  404. Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
  405. Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver
  406. Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry
  407. Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver
  408. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios
  409. Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
  410. CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …
  411. Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …
  412. Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene
  413. In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment
  414. Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells
  415. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
  416. Adenovirus-mediated expression of Cu/Zn-or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity
  417. CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck
  418. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
  419. Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
  420. Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice
  421. Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats
  422. … dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …
  423. Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol
  424. In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene
  425. Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
  426. Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians
  427. Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
  428. Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
  429. Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …
  430. Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells
  431. Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls
  432. Transcriptional and posttranscriptional regulation of CYP2E1, an N-nitrosodimethylamine demethylase.
  433. Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide
  434. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity
  435. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase
  436. Role of CYP2E1 in deramciclane metabolism
  437. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury
  438. The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis
  439. p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.
  440. Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone
  441. Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes
  442. Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Adenomas in the Self Defense Forces Health Study
  443. CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls
  444. The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
  445. Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts
  446. Role of CYP2E1 in the mouse model of MPTP toxicity
  447. Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals
  448. CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
  449. Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
  450. Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
  451. Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium
  452. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …
  453. Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar
  454. Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice
  455. Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase
  456. PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes
  457. In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
  458. Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells
  459. Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys
  460. … of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1
  461. Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily
  462. Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells
  463. Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression
  464. Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer
  465. A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping
  466. Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1
  467. APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population
  468. Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
  469. D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1
  470. Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
  471. Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals
  472. Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …
  473. Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
  474. Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …
  475. Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …
  476. Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …
  477. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells
  478. No significant expression of CYP2E1 in rat liver stellate cells
  479. CYP2E1 and clinical features in alcoholics
  480. Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
  481. Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1
  482. No Association between Polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the Risk of Gastric Adenocarcinoma in the European Prospective Investigation into …
  483. The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.
  484. A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans
  485. A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures
  486. Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1
  487. Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test
  488. Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity
  489. INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …
  490. Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet
  491. Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure
  492. Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
  493. Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast
  494. Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele
  495. Identification and functional analysis of a novel human CYP2E1 far upstream enhancer
  496. Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice
  497. Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
  498. Molecular cloning and sequence analysis of hamster CYP2E1
  499. Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism
  500. … mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …
  501. … overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1
  502. Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism
  503. [12] Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
  504. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
  505. Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …
  506. Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy
  507. Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
  508. Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
  509. Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system
  510. Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice
  511. Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
  512. Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes
  513. … of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …
  514. CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation
  515. CYP2E1 inhibition enhances mallory body formation
  516. XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …
  517. Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium
  518. Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone
  519. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity
  520. CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
  521. Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell
  522. The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
  523. Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats
  524. Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …
  525. Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
  526. Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …
  527. Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies
  528. Cytochrome P4502E1 (CYP2E1) Genetic Polymorphisms in a Lebanese Population: Frequency Distribution and Association with Morbid Diseases
  529. CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population
  530. THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION
  531. Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes
  532. Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury
  533. Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition
  534. Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …
  535. Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver
  536. Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene
  537. Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane
  538. A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population
  539. Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study
  540. CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform
  541. Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C
  542. Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm
  543. Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells
  544. Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone
  545. Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …
  546. Use of Duplex PCR-CTPP Methods for CYP2E1 RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C Polymorphisms
  547. Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse
  548. CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
  549. Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice
  550. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells
  551. Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity
  552. Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides
  553. Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene
  554. Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …
  555. Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C
  556. Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia
  557. Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases
  558. ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers
  559. The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase
  560. Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
  561. Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis
  562. Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic
  563. Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
  564. Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
  565. Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver
  566. The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat
  567. Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility
  568. Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in Mononuclear …
  569. Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
  570. Fetal and maternal CYP2E1 genotypes and the risk of nonsyndromic oral clefts
  571. Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
  572. Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells
  573. Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C
  574. IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
  575. Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism
  576. Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity
  577. Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism
  578. Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support
  579. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
  580. Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver
  581. Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice
  582. A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
  583. Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers
  584. Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …
  585. Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice
  586. Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
  587. Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys
  588. Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets
  589. Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)
  590. Insertion Polymorphism of the CYP2E1 gene in patients with infiltrative pulmonary tuberculosis from Bashkortostan
  591. Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats
  592. Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats
  593. Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease
  594. … , Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat
  595. Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida
  596. Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors
  597. Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats
  598. The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis
  599. Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung
  600. Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
  601. Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide
  602. CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury
  603. Case-control study of the polymorphisms of CYP2E1-RsaⅠ and STT1 genes and susceptibility to pancreatic cancer
  604. Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population
  605. Expression of human CYP2E1 in insect cells using bac-to-bac expression system
  606. A Case-control study on effects of genetic polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on risk of lung cancer
  607. Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells
  608. Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats
  609. … of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene
  610. No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia
  611. Antibodies against CYP2E1 after exposure to 1, 1, 1-trifluoroethane and 1, 1, 1, 2-tetrafluoroethane
  612. Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
  613. Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …
  614. CYP2E1 genotypes and serum LAP in Japanese alcoholics
  615. Genetic polymorphisms of CYP2E1
  616. Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons
  617. Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes
  618. The colorectal cancer risk of meat intake, smoking, and CYP2E1 polymorphisms: the comparison of colorectal cancer patients with controls
  619. Genetic Polymorphism of Alcohol Metabolizing Enzymes, CYP2E1
  620. Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis
  621. Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
  622. Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer
  623. Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes
  624. Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver
  625. Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats
  626. Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches
  627. Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …
  628. Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation
  629. Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer
  630. Effect of Genetic Polymorphisms of CYP2E1 and ALDH2 on the Relationship between the Levels of Urinary 8-Hydroxydeoxyguanosine and t, t-Muconic Acid
  631. Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
  632. Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality
  633. Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds
  634. GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer
  635. Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people
  636. Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
  637. A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1
  638. Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis
  639. Identification of polymorphisms in CYP2E1 gene and association analysis among chronic HBV patients
  640. Increase expression of CYP2E1 mRNA after methamphetamine administration in rats
  641. The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity
  642. Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice
  643. Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1
  644. Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity
  645. A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1
  646. Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium
  647. A study for regulation of ethanol-inducible P450 (CYP2E1) on CCl4-induced hepatic damage
  648. Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery
  649. Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
  650. Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions
  651. Relationship between alcoholism and CYP2E1 genotypes
  652. A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer
  653. Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice
  654. Association of genetic polymorphisms of aldehyde dehydrogenase II and CYP2E1 and clinical characteristics of patients with alcohol dependence
  655. Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis
  656. Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)
  657. Human CYP2E1 developmental expression: a role in fetal and pediatric susceptibility to toxicants?
  658. Effects of environmental carcinogens and genetic polymorphisms of CYP2E1 and NAT2 on gastric carcinogenesis
  659. Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice
  660. Fast CYP2E1 genotyping using automated fluorescent detection.
  661. Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children
  662. Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity
  663. CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase
  664. Expression and regulation of cytochrome P450 CYP2E1 in the minipig
  665. Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.
  666. Effects of ginsenoside Rd and Panax ginseng extract on Cyp1a, Cyp2b, Cyp2c, CYP2E1, and Cyp3a activities in C57BL/6JNarl mice
  667. The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer
  668. Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons
  669. CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population
  670. Ontogeny of Rat CYP2E1 and CYP1A2: A Characterization and
  671. Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
  672. The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates
  673. Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity
  674. Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals
  675. Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.
  676. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
  677. Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity
  678. Effect of total saikosaponins on the intestinal first-pass effect and liver Cyp3a, CYP2E1
  679. Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene
  680. High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats
  681. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
  682. Silibinin inhibits CYP2E1‐dependent ethanol metabolism, oxidative stress and cell proliferation in a rat model of hepatocellular carcinoma (HCC)
  683. Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)
  684. Computational docking studies of nitroanisoles and nitrophenols with CYP2E1
  685. ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
  686. Role of CYP2E1 in Hepatocarcinogenesis and Hepatotoxicity
  687. An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies
  688. Formation of Multiple CYP2E1 Complexes Affects Activity
  689. Regulation of CYP2E1 and Tissue Protection Effect of CYP2E1 Inhibitor
  690. Mapping of pig CYP2E1 to SSC14
  691. ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
  692. CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability
  693. Alcohol, Nicotine and Genetic Variation Influence CYP2E1
  694. Different CYP2E1 genotypes and alcoholic liver disease.
  695. Establishment and toxicological application of a cell line expressing human CYP2E1
  696. The Toxicological Mechanism Of Styrene In CYP2E1 Transgenic Cells
  697. Effect of CYP2E1 Ras I genotypes on CYP2E1 enzyme activity and DNA damage induced by phenol in immortalized human lymphocytes
  698. Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice
  699. Molecular Evidence for the Presence of CYP2E1 Retropseudogene in Human Genome
  700. Role Of Mouse CYP2E1 In The O-Hydroxylation Of P-Nitrophenol: Comparison Of Activities In CYP2E1 (-/-) And Wildtype Mice
  701. Structure-functional characterization of cytochrome P4502E1 (CYP2E1)
  702. Establishment of model with exogenous human CYP2E1 expression and inducement of substrates
  703. Chlorzoxazone as a Single Sample Probe of Hepatic CYP2E1 Activity
  704. A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population
  705. Application of a map Bayesian method for CYP2E1 phenotyping
  706. Role of CYP2E1 Immunoglobulin G4
  707. Individual variability of CYP2E1 xenobiotic oxidation in human liver
  708. The genotype of CYP2E1 and liver-derived serum enzymes
  709. A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA
  710. Pathogenesis of nonalcoholic steatohohepatitis [sic]: the role of CYP2E1
  711. Hormonal regulation of CYP2E1 and CYP2C11 in rat liver and kidney
  712. Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract
  713. Immunological detection of CYP2E1 in the fresh lymphocytes
  714. THE EFFECT OF COPROPHAGY ON THE EXPRESSION OF HEPATIC CYP2E1 DURING STARVATION
  715. Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate
  716. Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects
  717. CYP2E1-DEPENDENT BIOACTIVATION OF 191
  718. Role Of Cytochrome P450 2E1 (CYP2E1) In Trichloroethylene (TCE) Metabolism And Disposition: Comparative Studies Using CYP2E1-/-And Wild-Type Mice
  719. The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis
  720. CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation
  721. Substrate inhibition of CYP2E1 activity is primarily determined by lipophilicity
  722. Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice
  723. Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease
  724. An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.
  725. The Effects of CYP2E1 and CYP2C19 Polymorphisms on the Susceptibility for Gastric Cancer
  726. Time-coursed Changes of CYP2E1 Protein in Acute Liver Injury by a Single CCI₄ Administration in SD Rats
  727. Search for possible changes in murine gene CYP2E1 structural region under exposure to ionizing radiation
  728. MAPPING CONFORMATIONAL CYP2E1 EPITOPES RECOGNISED BY AUTO-ANTIBODIES IN HALOTHANE HEPATITIS AND ALCOHOLIC LIVER DISEASE
  729. The Genetic Polymorphism of CYP2E1 in a Korean Healthy Subjects and Hepatocellular Carcinoma Patients
  730. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio
  731. CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers
  732. Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1
  733. Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1
  734. ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES
  735. e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice
  736. Catalytic activity and quantitation of CYP2E1 in human embryonic and fetal brain tissues
  737. Various Fatty Acids Induce Cell Damages Differently in CYP2E1-transduced HepG2 Cells, E47 Cells, Compared to C34 Cells
  738. Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world
  739. Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA
  740. The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury
  741. Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)
  742. Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
  743. Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …
  744. The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.
  745. Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption
  746. Increased citrate levels in non-alcoholic steatohepatitis: effect on CYP2E1
  747. The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization
  748. Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.
  749. Meta-analysis on relationship between polymorphisms of CYP2E1 gene and susceptibility to antituberculosis drug-induced liver injury
  750. Modulation of Murine CYP2E1 Activity by Disulfiram on Trichloroethylene-Induced Neurotoxicity A Pilot Study
  751. Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.
  752. Single Nucleotide Polymorphisms in the Non-coding region of CYP2E1 among Koreans
  753. The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1
  754. Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice
  755. Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).
  756. Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …
  757. The Effects of Chungganhaeju-tang(Qingganjiejiu-tang) on Alcohol induced Cytotoxicity in CYP2E1-transfected HepG2 cells.
  758. Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
  759. CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation
  760. Analyses of Mutation Frequency on the CYP2E1, ADH2, and ALDH2 Genes among Five Ethnic Groups
  761. Molecular Regulation of Ethanol-inducible P450 (CYP2E1) in Acute CCI₄Treatment
  762. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.
  763. CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells
  764. Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism
  765. Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
  766. The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine
  767. Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma
  768. THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.
  769. Cytochrome P450 2E1 (CYP2E1) Induction By Pyridazine Produces Qualitative And Quantitative Changes In The Metabolism Of Trichloroethylene To Potentially …
  770. Inhibition of B12‐dependent methionine synthase activity in HepG2 cells over‐expressing CYP2E1
  771. Overexpression of CYP2E1 Increases Sensitivity of HepG2 Cells to Isoniazid-Induced Cytotoxicity
  772. Relation between genetic polymorphisms of ADH, CYP2E1, GSTP1 and their expression in Caucasian lung tissue
  773. Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C
  774. Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics
  775. RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES
  776. NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …
  777. Single nucleotide polymorphisms and variable number of tandem repeat polymorphism of CYP2E1 in Koreans
  778. Strain-related Differences in CYP2E1 Levels are Associated with Differential Bioactivation of 1, 1-dichloroethylene in Murine Lung and Liver
  779. Inductive Effect Of Pyridazine (Pz) On Cytochrome P4502E1 (CYP2E1) Alters The Metabolism Of Trichloroethylene (TCE)
  780. Interactive effects between genetic polymorphisms of CYP2E1 & NAT1 and smoking on the development of lung cancer in Korean
  781. RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES-STUDIES …
  782. AhR Mediated Hematotoxicity Is Induced At The Site Of Bone Marrow Where Consequent CYP2E1-Derived Benzene Metabolites Locally Induce Their Toxicity
  783. The potent protective effect of red ginseng against acetaminophen-induced toxicity through metabolic regulation of CYP2E1 and GSTs
  784. CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
  785. Effects of CYP Inducers and Inhibitors on the Furosemide Pharmacokinetics: Involvement of CYP2E1 and 3A 1/2 for the Furosemide Metabolism
  786. Effect of tobacco smoke on the expression of Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mice. Possible role of CYP2E1 in pulmonary DNA single strand breaks …
  787. Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems
  788. An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations
  789. Effects of in vivo hepatic ischemia‐reperfusion injury on the CYP2E1‐mediated metabolism of chlorzoxazone and biliary clearance of its metabolite in isolated …
  790. Assessment of the role of cytochrome P450 2E1 (CYP2E1)-mediated metabolism in urethane-induced cell proliferation and gene expression: Biomarkers of …
  791. Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2
  792. … of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1
  793. Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population
  794. Alkyl sulfides Potentiation of Carbon Tetrachloride-induced Hepatotoxicity: The Role of CYP2E1 Expression
  795. The influence of alcohol on acetaminophen hepatotoxicity: CYP2E1 induction and selective mitochondrial glutathione depletion
  796. Interaction of genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and CYP2E1 in development of lung cancer
  797. A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene
  798. A Composition of Metadoxine and Garlic Oil Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with AMPK Restoration
  799. The Association between Pneumoconiosis and Genetic Polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1
  800. The effect of trans-resveratrol analogues on the catalytic activities of CYP1A2 and CYP2E1 in mouse liver microsomes in vitro
  801. Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption
  802. Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction
  803. The Role of Genetic Polymorphisms of CYP2E1, CYP1A1, NAT1, and NAT2 in Bladder Cancer in Korea
  804. Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …
  805. Diphenyl-Dimethyl-Dicarboxylate Inhibits Carbon tetrachloride-induced Increase Kupffer Cell Counts in the Absence of CYP2E1 Suppression in the Rat
  806. Diallyl Sulfone, a Derivative of Garlic, Inactivates the Cytochrome P450 Enzyme CYP2E1 by Forming N-alkylprotoporphyrin Heme Adducts
  807. EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …
  808. … Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism
  809. MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA
  810. Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …
  811. Saponins Isolated from the Root of Platycodi Radix Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with Restoration of AMPK Activity
  812. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …
  813. Identification of 2‐Piperidone as a Biomarker of CYP2E1 Activity through Metabolomic Phenotyping
  814. The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …
  815. Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking
  816. IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …
  817. Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1
  818. CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease
  819. The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system
  820. The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
  821. Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
  822. Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
  823. New insight and potential therapy for NAFLD: CYP2E1 and flavonoids
  824. A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
  825. Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
  826. CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
  827. Induction of CYP2E1 in non-alcoholic fatty liver diseases
  828. Molecular dynamics simulations of CYP2E1
  829. Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen
  830. CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat
  831. Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness
  832. Higher CYP2E1 activity correlates with hepatocarcinogenesis induced by diethylnitrosamine
  833. CYP2E1 autoantibodies in liver diseases
  834. Role of CYP2E1 in mitochondrial dysfunction and hepatic injury by alcohol and non-alcoholic substances
  835. CYP2E1 in alcoholic and non-alcoholic liver injury. Roles of ROS, reactive intermediates and lipid overload
  836. Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
  837. Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem
  838. Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway
  839. Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
  840. Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity
  841. Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
  842. Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity
  843. NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways
  844. The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects
  845. Downregulation of CYP2E1 is associated with poor prognosis and tumor progression of gliomas
  846. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction
  847. … psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
  848. Nrf2 and antioxidant defense against CYP2E1 toxicity
  849. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability
  850. MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
  851. Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway
  852. Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
  853. Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis …
  854. Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy
  855. Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure
  856. Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2
  857. Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1
  858. Involvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro
  859. Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis
  860. Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
  861. Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol
  862. CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid
  863. Protective effects of taraxasterol against ethanol-induced liver injury by regulating CYP2E1/Nrf2/HO-1 and NF-κB signaling pathways in mice
  864. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …
  865. CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
  866. Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB
  867. Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK
  868. Toxicological implications of mitochondrial localization of CYP2E1
  869. Alcoholic liver disease: from CYP2E1 to CYP2A5
  870. Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
  871. CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study
  872. Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver
  873. Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation
  874. … effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
  875. Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol
  876. Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …
  877. Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1
  878. Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme
  879. Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
  880. Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion
  881. CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit
  882. The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis
  883. Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans
  884. Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …
  885. Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress …
  886. CYP2E1 metabolism of styrene involves allostery
  887. ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes
  888. Sex‐dependent regulation of cytochrome P450 family members Cyp1a1, CYP2E1, and Cyp7b1 by methylation of DNA
  889. The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes
  890. Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
  891. Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis
  892. CYP2E1 regulates the development of radiation-induced pulmonary fibrosis via ER stress-and ROS-dependent mechanisms
  893. CYP2E1*5B, CYP2E1*6, CYP2E1*7B, CYP2E1*2, and CYP2E1*3 Allele Frequencies in Iranian Populations
  894. Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
  895. Investigating the CYP2E1 potential role in the mechanisms behind INH/LPS-induced hepatotoxicity
  896. Enantioselective metabolism of phenylpyrazole insecticides by rat liver microsomal CYP3A1, CYP2E1 and CYP2D2
  897. CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
  898. CYP2E1 hydroxylation of aniline involves negative cooperativity
  899. Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation
  900. Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions
  901. Functional PstI/RsaI Polymorphism in CYP2E1 Is Associated with the Development, Progression and Poor Outcome of Gastric Cancer
  902. CYP2E1 RsaI/PstI polymorphism and risk of anti-tuberculosis drug-induced liver injury: a meta-analysis
  903. Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences
  904. Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury
  905. Prilocaine-and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation
  906. CYP2E1 sensitizes the liver to LPS-and TNF α-induced toxicity via elevated oxidative and nitrosative stress and activation of ASK-1 and JNK mitogen …
  907. Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway
  908. Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites
  909. Why hepatic CYP2E1-elevation by itself is insufficient for inciting NAFLD/NASH: Inferences from two genetic knockout mouse models
  910. Amalgamation of in-silico, in-vitro and in-vivo approach to establish glabridin as a potential CYP2E1 inhibitor
  911. Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice
  912. High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines
  913. Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …
  914. Relevance of CYP2E1 to non-alcoholic fatty liver disease
  915. Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS
  916. Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells
  917. Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570
  918. CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis
  919. The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
  920. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population
  921. Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
  922. Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway
  923. CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol
  924. Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST
  925. Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers
  926. … final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …
  927. Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects
  928. CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
  929. Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates
  930. Contributing roles of CYP2E1 and other cytochrome P450 isoforms in alcohol-related tissue injury and carcinogenesis
  931. Stat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway
  932. Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells
  933. CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis
  934. Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids
  935. CYP2E1 gene promoter polymorphism-1293G> C increases the risk of essential hypertension in men with alcohol abuse
  936. Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)
  937. Interactions of inhibitor molecules with the human CYP2E1 enzyme active site
  938. Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers
  939. Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse
  940. Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders
  941. A case control study on relationship between lung cancer and genetic polymorphism of CYP1A1, CYP2E1 and GSTM1 in Han Nationality in Guangzhou area
  942. A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer
  943. A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …
  944. A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer
  945. A Case-Control Study on Effects of Genetic Polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on Risk of Lung Cancer.
  946. A comparison of substrate dynamics in human CYP2E1 and CYP2A6
  947. A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
  948. A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1
  949. A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene.
  950. A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans
  951. A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate
  952. A Meta-analysis of CYP2E1 Genetic Polymorphism and Gastric Cancer Susceptibility [J]
  953. A meta-analysis on association of CYP2E1 rs2031920 and rs3813867 polymorphisms with breast cancer risk
  954. A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping
  955. A Nanosensor System Based On Disuccinimydyl–CYP2E1 for Amperometric Detection of the Anti-Tuberculosis Drug, Pyrazinamide
  956. A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations
  957. A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1
  958. A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a …
  959. A novel role of CYP2E1 in human megakaryocyte development
  960. A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population
  961. A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures
  962. A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma
  963. A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population
  964. A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
  965. A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations
  966. A study for regulation of ethanol-inducible P450(CYP2E1) on CCl4-induced hepatic damage
  967. A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells
  968. A Study on the Optimization of CYP2E1 Enzyme Activity in C57Bl/6 Mouse Brain and Liver/C57Bl/6 Fare Beyin ve Karaciger Mikrozomlarinda CYP2E1 Enzim …
  969. A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
  970. A systematically combined genotype and functional combination analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in different geographic areas of mainland …
  971. A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice
  972. A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA
  973. Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide
  974. Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
  975. Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
  976. Acetaldehyde as well as ethanol is metabolized by human CYP2E1
  977. Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes
  978. Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1
  979. Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation
  980. Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
  981. Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice
  982. Aconitine, a famous active and toxic alkaloid, has no impact on the activities of CYP1A2, CYP2D6, CYP2E1, and CYP3A in rats
  983. Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons
  984. Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)
  985. Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics
  986. Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support
  987. Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways
  988. Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes
  989. Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity
  990. Adenovirus‐mediated expression of Cu/Zn‐or Mn‐superoxide dismutase protects against CYP2E1‐dependent toxicity
  991. Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
  992. ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects
  993. Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …
  994. Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective
  995. Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1
  996. Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome
  997. Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats
  998. Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
  999. ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …
  1000. Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis
  1001. Alcohol Suppresses Cardiovascular Diurnal Variations In Male Normotensive Rats: Role Of Reduced PER2 Expression And CYP2E1 Hyperactivity In The Heart
  1002. Alcoholic liver disease: from CYP2E1 to CYP2A5
  1003. Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity
  1004. ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers
  1005. All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …
  1006. Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …
  1007. ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES
  1008. Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse
  1009. Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR
  1010. Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction
  1011. Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats
  1012. Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats
  1013. An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations
  1014. An improved in vitro method for screening toxin and medicine targeting CYP2E1
  1015. An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)
  1016. An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies
  1017. An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.
  1018. An Rsa I Polymorphism in the CYP2E1 Gene Does Not Affect Lung Cancer Risk in a Japanese Population
  1019. An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies
  1020. Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer
  1021. Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
  1022. Analysis of CYP2E1, GSTM1 genetic polymorphisms in relation to human lung cancer and esophageal carcinoma
  1023. Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling
  1024. Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …
  1025. Analysis of human CYP2E1 mRNA in a HepG2 cell line by reverse transcription-polymerase chain reaction (RT-PCR)
  1026. Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population.
  1027. Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and …
  1028. and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1
  1029. Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver
  1030. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
  1031. Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
  1032. Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol
  1033. Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation
  1034. Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …
  1035. APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population
  1036. Application of a map Bayesian method for CYP2E1 phenotyping
  1037. Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice
  1038. Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in …
  1039. Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats
  1040. Assessing Specificity of Indazole Derivatives as Inhibitors to CYP2E1
  1041. Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …
  1042. Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis
  1043. Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population
  1044. Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N,N-dimethylformamide occupational exposure-induced liver injury
  1045. Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis
  1046. Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma
  1047. Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies
  1048. Association between genetic polymorphism of GSTM1, CYP2E1 and susceptibility to cervical cancer and its precancerous lesions in Uighur women in Xinjiang
  1049. Association between genetic polymorphisms of CYP2E1 and lung cancer susceptibility: a case control study
  1050. Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis
  1051. Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity
  1052. Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …
  1053. Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis
  1054. Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer
  1055. Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
  1056. Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease
  1057. Association of CYP2E1 gene polymorphism with predisposition to cancer development
  1058. Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis
  1059. Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm
  1060. Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide
  1061. Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children
  1062. Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
  1063. Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review and meta …
  1064. Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population
  1065. Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population
  1066. Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran
  1067. Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis
  1068. Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity
  1069. Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid
  1070. Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …
  1071. Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population
  1072. Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls
  1073. Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China
  1074. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio
  1075. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios
  1076. Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens
  1077. Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis
  1078. Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery
  1079. Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1
  1080. Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
  1081. Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity
  1082. B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …
  1083. Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …
  1084. Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition
  1085. bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …
  1086. Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation
  1087. Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)
  1088. Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans
  1089. Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung
  1090. Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
  1091. Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.
  1092. Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis
  1093. Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
  1094. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription
  1095. Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
  1096. Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry
  1097. Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice
  1098. by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3
  1099. Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1
  1100. Camelus dromedarius Putative Cytochrome P450 Enzyme CYP2E1: Complete Coding Sequence and Phylogenetic Tree
  1101. Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1
  1102. CARBON MONOXIDE PROTECTS MICROSOMES FROM ETHANOL-DERIVED OXIDATIVE STRESS MEDIATED BY CYP2E1
  1103. Case Control Study of Genetic Polymorphism of Cytochrome P4502E1 5′(CYP2E1 5′) and Susceptibility of Occupational Manganism [J]
  1104. Case-control study of the polymorphisms of CYP2E1-RsaⅠ and GSTT1 genes and susceptibility to pancreatic cancer
  1105. CCl 4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat
  1106. cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1
  1107. Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology
  1108. Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …
  1109. Changes of CYP2E1 activity in diabetic rat model
  1110. Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity
  1111. Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
  1112. Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population
  1113. Chemical characteristics for optimizing CYP2E1 inhibition
  1114. CHIP−/−-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Thhttps://journals.lww.com/ajg/Fulltext/2007/09002/Association_of_GSTM1,_P1erapeutic Implications
  1115. Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.
  1116. Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
  1117. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1
  1118. Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts
  1119. Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans
  1120. Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
  1121. Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
  1122. Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy
  1123. Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …
  1124. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase
  1125. Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)
  1126. Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides
  1127. Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA
  1128. Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma
  1129. Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
  1130. Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
  1131. Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches
  1132. Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice
  1133. Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats
  1134. Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
  1135. Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C
  1136. Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups
  1137. Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
  1138. Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
  1139. COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …
  1140. Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys
  1141. Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide
  1142. Compatible effects of euphorbia and glycyrrhiza on CYP2E1 expression and activity in rat liver
  1143. Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1
  1144. Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1
  1145. Computational docking studies of nitroanisoles and nitrophenols with CYP2E1
  1146. Concentration-dependent inhibitory effect of Baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …
  1147. Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C
  1148. Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice
  1149. Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations
  1150. Construction and Identification of miRNA Expression Vector Targeting on Mouse CYP2E1
  1151. Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order
  1152. Construction of CRISPR/Cas9-mediated genomic deletion of the CYP2E1 gene in human HEK293FT cell line
  1153. Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects
  1154. Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis
  1155. Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
  1156. Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers
  1157. Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism
  1158. Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers
  1159. Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
  1160. CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …
  1161. Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures
  1162. Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
  1163. Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
  1164. Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality
  1165. Correlation between genetic polymorphism in CYP2E1, GST and toxicity of dimethylformamide
  1166. CORRELATION BETWEEN GENETIC POLYMORPHISM OF CYP2E1 AND SUSCEPTIBILITY OF ESOPHAGEAL CANCER IN GANSU PROVINCE
  1167. Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province
  1168. Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province [J]
  1169. CORRELATION BETWEEN GENETIC POLYMORPHISMS OF CYP2E1 RSAⅠ AND SUSCEPTIBILITY OF GASTRIC CANCER IN QINGHAI PROVINCE [J]
  1170. Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes
  1171. Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
  1172. Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen
  1173. Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
  1174. Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol‐Drug Interactions.
  1175. Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
  1176. Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.
  1177. Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria
  1178. CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau
  1179. CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir
  1180. CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus
  1181. CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …
  1182. CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
  1183. CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population
  1184. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
  1185. CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese
  1186. CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head …
  1187. CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …
  1188. CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
  1189. CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India
  1190. CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro
  1191. CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism
  1192. CYP2E1
  1193. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
  1194. CYP2E1 activity and children with obesity: possible confounding factors
  1195. CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
  1196. CYP2E1 activity in cisplatin resistant cancer cells
  1197. CYP2E1 activity in patients with alcoholic liver disease
  1198. CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism
  1199. CYP2E1 and ALDH2 Gene Polymorphisms in Squamous Cell Head and Neck
  1200. CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck cancer in the Turkish population
  1201. CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese
  1202. CYP2E1 and clinical features in alcoholics
  1203. CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation
  1204. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
  1205. CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer
  1206. CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity
  1207. CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
  1208. CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease
  1209. CYP2E1 and oxidative liver injury by alcohol
  1210. CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
  1211. CYP2E1 and risk of chemically mediated cancers
  1212. CYP2E1 autoantibodies in liver diseases
  1213. CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
  1214. CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase
  1215. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90
  1216. CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells
  1217. CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit
  1218. CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …
  1219. CYP2E1 expression in human lymphocytes from various ethnic populations
  1220. CYP2E1 Expression in Liver of Type 2 Diabetic Rats [J]
  1221. CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck
  1222. CYP2E1 gene polymorphism and ovarian cancer risk in the Yakut population
  1223. CYP2E1 GENE POLYMORPHISM AND SUSCEPTIBILITY OF HEPATOCELLULAR CARCINOMA IN QINGHAI TIBETAN POPULATION
  1224. CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease
  1225. CYP2E1 Gene Promoter Polymorphism -1293G>C Increases the Risk of Essential Hypertension in Men with Alcohol Abuse
  1226. CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China
  1227. CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers
  1228. CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
  1229. CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis
  1230. CYP2E1 genotype and transaminase level of tuberculosis patients receiving fixed dose combination of antituberculosis
  1231. CYP2E1 genotypes and serum LAP in Japanese alcoholics
  1232. CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
  1233. CYP2E1 hydroxylation of aniline involves negative cooperativity
  1234. CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia
  1235. CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator
  1236. CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol
  1237. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
  1238. CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
  1239. CYP2E1 inhibition enhances mallory body formation
  1240. CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation
  1241. CYP2E1 is not involved in early alcohol-induced liver injury
  1242. CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.
  1243. CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform
  1244. CYP2E1 mediated ethanol metabolism in ARPE-19 cells.
  1245. CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells
  1246. CYP2E1 metabolism of styrene involves allostery
  1247. CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers
  1248. CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability
  1249. CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
  1250. CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase
  1251. CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
  1252. CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
  1253. CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
  1254. CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene
  1255. CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients
  1256. CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis
  1257. CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians
  1258. CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis
  1259. CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
  1260. CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
  1261. CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …
  1262. CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
  1263. CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis
  1264. CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls
  1265. CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults
  1266. CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
  1267. CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population
  1268. CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
  1269. CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls
  1270. CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis
  1271. CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians
  1272. CYP2E1 RsaⅠpolymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
  1273. CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies
  1274. CYP2E1 Rsai/Psti polymorphisms contributed to oral cancer susceptibility: A meta-analysis
  1275. CYP2E1 substrate inhibition mechanistic interpretation through an effector site for monocyclic compounds
  1276. CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.
  1277. CYP2E1 substrate inhibition..
  1278. CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls
  1279. CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity
  1280. CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation
  1281. CYP2E1* 5B, CYP2E1* 6, CYP2E1* 7B, CYP2E1* 2, and CYP2E1* 3 allele frequencies in Iranian populations
  1282. CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study
  1283. CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity
  1284. CYP2E1, oxidative stress, post-translational modifications and lipid metabolism
  1285. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury
  1286. CYP2E1: from ash to nash
  1287. CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation.
  1288. CYP2E1: the anesthesia enzyme
  1289. CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease
  1290. CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury
  1291. CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy
  1292. CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice
  1293. CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
  1294. CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism
  1295. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
  1296. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.
  1297. CYP2E1-DEPENDENT BIOACTIVATION OF 191
  1298. CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid
  1299. CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
  1300. CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury
  1301. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
  1302. CYP2E1-dependent toxicity and up-regulation of antioxidant genes
  1303. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
  1304. CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
  1305. CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
  1306. CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
  1307. Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium
  1308. Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium
  1309. Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test
  1310. Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation
  1311. Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments
  1312. Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice
  1313. Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
  1314. Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
  1315. Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver
  1316. Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
  1317. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver
  1318. Cytochrome P450 Genes (CYP2E1 and CYP1A1) Variants and Susceptibility to Chronic Hepatitis B Virus Infection
  1319. Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism
  1320. Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes
  1321. Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
  1322. Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
  1323. Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets
  1324. D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1
  1325. Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases
  1326. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1
  1327. dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …
  1328. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells
  1329. Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …
  1330. Detection and characterization of novel polymorphisms in the CYP2E1 gene.
  1331. Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C
  1332. Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C
  1333. Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese population
  1334. Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1
  1335. Development and properties of HepG2 cells that constitutively express CYP2E1
  1336. Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes
  1337. Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines
  1338. Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period
  1339. Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality
  1340. Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
  1341. Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats
  1342. Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean
  1343. Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells
  1344. Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue
  1345. Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites
  1346. Different CYP2E1 genotypes and alcoholic liver disease.
  1347. Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region
  1348. Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
  1349. Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver
  1350. Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells
  1351. Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
  1352. Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity
  1353. Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney
  1354. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
  1355. Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
  1356. Differential Modulation of CYP2E1 Activity by cAMP-Dependent Protein Kinase upon Ser129Replacement
  1357. Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …
  1358. Differential role of CYP2E1-mediated metabolism in the lethal and vestibulotoxic effects of cis-crotononitrile in the mouse
  1359. Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors
  1360. Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …
  1361. Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat
  1362. Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population
  1363. Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration
  1364. DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1
  1365. DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1
  1366. DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil
  1367. DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …
  1368. Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?
  1369. Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage
  1370. Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?
  1371. Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies
  1372. Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis
  1373. Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells
  1374. Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?
  1375. Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
  1376. e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice
  1377. Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A
  1378. Effect of {gamma}-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
  1379. Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats
  1380. effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
  1381. Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers
  1382. Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury
  1383. Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes
  1384. Effect of BI-1 on insulin resistance through regulation of CYP2E1
  1385. Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1
  1386. Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects
  1387. Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung
  1388. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
  1389. Effect of CYP2E1 genetic polymorphisms on susceptibility of aplastic anemia
  1390. Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure
  1391. Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility
  1392. Effect of CYP2E1 Ras I Genotypes on CYP2E1 Enzyme Activity and DNA Damage of Immortalized Human Lymphocytes Induced by Phenol
  1393. Effect of different radix polygoni multiflori preparata on CYP2E1 mRNA expression in rat liver [J]
  1394. Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone
  1395. Effect of Er Chen Tang on CYP2E1 and Mitochondrial Energy Metabolism in Nonalcoholic Fatty Liver Disease
  1396. Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
  1397. Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam
  1398. Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
  1399. Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity
  1400. Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.
  1401. Effect of Ganzheng formula on CYP2E1, adiponectin and TNF-α in NAFLD rats
  1402. Effect of Gegen Powder on CYP450 Content of Liver Microsomal and Activity of CYP2E1 in Mice Acute Alcohol-induced Liver Injury
  1403. Effect of genetic polymorphisms of toxin metabolic enzyme CYP2E1 on metabolism of styrene
  1404. Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
  1405. Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease
  1406. Effect of Leflunomide on the content of cytochrome P450 enzyme and CYP2E1 mRNA expression of mice with acute chemical injury [J]
  1407. Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats
  1408. EFFECT OF NARINGIN ON THE ACTIVITY OF HUMAN LIVER MICROSOMES CYP2E1 USING PROBE DRUG METHOD
  1409. Effect of neferine on CYP450 total enzyme and CYP3A1, CYP2D1, CYP2E1 mRNA in Rats
  1410. Effect of oleanolic acid on CYP1A2, CYP2E1 and CYP3A4 activity in healthy subjects
  1411. Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers
  1412. Effect of quercetin on CYP1A2, CYP2E1, CYP3A2 activities and its inhibitory mechanism studies in rat liver microsomes
  1413. Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …
  1414. Effect of Sanchi on expression of hepatic CYP2E1 in liver tissues in rats with alcoholic liver disease [J]
  1415. Effect of Seed Coat ofEuryale ferox Extract in Non-alcoholic Fatty Liver Disease Induced by High-fat Diet in Mice by Increasing IRs-1 and Inhibiting CYP2E1
  1416. Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats
  1417. Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
  1418. Effect of Sulfamethoxazole, Glycyrrhiza Uralensis Fisc and Fisch Fructus Forsythiae on Cytochrome CYP2E1 in Paralichthys Olivaceus by Probe Drugs
  1419. Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
  1420. Effect of temperature on carp CYP2E1-like isoform activity.
  1421. Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.
  1422. Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
  1423. Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2
  1424. EFFECT OF TOTAL ALKALOIDES OF ACONITUM EXCELSUM REICHB ON CYP2E1 METABOLISM ACTIVITY IN MORPHINE DEPENDENT RATS [J]
  1425. Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury
  1426. Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes
  1427. Effect of XiaozhiHugan Capsule on Pathologic Changes and CYP2E1 Gene Expression of Rats with Non-alcoholic Fatty Liver [J]
  1428. Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
  1429. Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells
  1430. Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …
  1431. Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans
  1432. Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells
  1433. Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …
  1434. Effects of blueberry on ultrastructural and expression of cytochrome CYP2E1 in rats with immune hepatic fibrosis
  1435. Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
  1436. Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
  1437. Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate
  1438. Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …
  1439. Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …
  1440. Effects of Environmental Carcinogens and Genetic Polymorphisms of CYP2E1 and NAT2 on Gastric Carcinogenesis.
  1441. Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice
  1442. Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet
  1443. Effects of flavonoids in Lysimachia clethroides duby on the activities of cytochrome P450 CYP2E1 and CYP3A4 in rat liver microsomes
  1444. Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats
  1445. Effects of Ganzhengfufang on the PPARγ and CYP2E1 in the rat with nonalcoholic fatty liver disease
  1446. Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers
  1447. Effects of GSTM1 and CYP2E1 Genetic Polymorphism and Drinking on DNA Damage among Workers Exposed to Phenol and Acetone
  1448. Effects of metadoxine on the expression of CYP2E1 in liver tissue of male rats with alcoholic fat liver [J]
  1449. Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
  1450. Effects of mitomycin (MMC) and γ-ray irradiation on cytochome p450 content and activities of CYP2B1and CYP2E1 in rats [J]
  1451. Effects of mitomycin (MMC) and γ-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
  1452. Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …
  1453. Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats
  1454. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations
  1455. Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice
  1456. Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
  1457. Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …
  1458. Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism
  1459. EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …
  1460. Effects of SU-MIAN-XIN on CYP3A1 and CYP2E1 in Rat Primary Cultured Hepatocytes
  1461. Effects of the activities and mRNA level of CYP2E1 in mouse liver microsomal by Folium Isatidis
  1462. Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
  1463. Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620
  1464. Effects of Trichloroethylene Toxicity on Normal Human Liver Cells and Hepatocytes With CYP2E1 Gene Overexpression
  1465. Effects of Zhenyuan Capsule on Cytochrome P450 Enzymes CYP1A2, CYP3A4 and CYP2E1
  1466. Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I
  1467. Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking
  1468. Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
  1469. End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes
  1470. Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …
  1471. ‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …
  1472. Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats
  1473. Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
  1474. Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats
  1475. Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
  1476. Establishment and toxicological application of a cell line expressing human CYP2E1
  1477. Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro
  1478. Establishment of model with exogenous human CYP2E1 expression and inducement of substrates
  1479. Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol
  1480. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1
  1481. Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion
  1482. Ethanol induces CYP2E1 by protein stabilization role of ubiquitin conjugation in the rapid degradation of CYP2E1
  1483. Ethanol induction of CYP2A5: permissive role for CYP2E1
  1484. Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway
  1485. Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
  1486. Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341
  1487. Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice
  1488. Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1
  1489. Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
  1490. Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1
  1491. Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions
  1492. Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver
  1493. Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells
  1494. Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
  1495. Evaluation of activity of hepatic CYP2E1 following administration of Radix et Rhizoma Rhei by probe drug in rats [J]
  1496. Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations
  1497. Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …
  1498. Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone
  1499. Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals
  1500. Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood
  1501. Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs
  1502. Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells
  1503. Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse
  1504. Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
  1505. Experimental study on the effects of combined administration of Shuanghuanglian powder for injection and levofloxacin hydrochloride injection on CYP2E1 in mice
  1506. exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …
  1507. Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals
  1508. Expression and regulation of cytochrome P450 CYP2E1 in the minipig
  1509. Expression of CYP2E1 by human monocyte‐derived macrophages
  1510. Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples
  1511. Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice
  1512. Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
  1513. Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …
  1514. Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro
  1515. Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice
  1516. Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
  1517. Expression of human CYP2E1 in insect cells using bac-to-bac expression system
  1518. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
  1519. Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …
  1520. Fast CYP2E1 genotyping using automated fluorescent detection.
  1521. Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—Impact of the extent of ortho-chlorination
  1522. Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …
  1523. final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …
  1524. for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
  1525. Formation of multiple CYP2E1 complexes affects activity
  1526. Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations
  1527. Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population
  1528. Functional analyses of the pig CYP2E1 promoter and identification of the transcription factors required for CYP2E1 expression
  1529. Functional CYP2E1 is required for substantial in vivo formation of 2,5-hexanedione from n-hexane in the mouse
  1530. Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels
  1531. Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.
  1532. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
  1533. Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1
  1534. Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1
  1535. Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation
  1536. Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily
  1537. Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …
  1538. Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone
  1539. Genetic Interaction between NAT2, GSTM1, GSTT1, CYP2E1, and Environmental Factors Is Associated with Adverse Reactions to Anti-Tuberculosis Drugs
  1540. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population
  1541. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China
  1542. Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity
  1543. Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds
  1544. Genetic polymorphism of CYP2D6, CYP2E1 and susceptibility to chronic occupational manganism poisoning [J]
  1545. Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals
  1546. Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans
  1547. Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …
  1548. Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients
  1549. Genetic polymorphism of human CYP2E1: characterization of two variant alleles
  1550. Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions
  1551. Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population
  1552. Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese
  1553. Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population
  1554. Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
  1555. Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors
  1556. Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma
  1557. Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population
  1558. Genetic Polymorphisms of CYP1A1, CYP2E1, and GSTM1 Genes: Susceptibility to Colon Cancer
  1559. Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer
  1560. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
  1561. Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer
  1562. Genetic polymorphisms of CYP2E1 and GSTM1 and T1 on susceptibility to esophageal cancer in Huaian, China
  1563. Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity
  1564. Genetic polymorphisms of CYP2E1 and risk of colorectal adenomas in the Self Defense Forces Health Study
  1565. Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study
  1566. Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women
  1567. Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.
  1568. Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
  1569. Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …
  1570. Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
  1571. Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption
  1572. Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients
  1573. Genetic Polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and Susceptibility to Anti-Tuberculosis Drug-Induced Hepatotoxicity: A Chinese Population-Based …
  1574. Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida
  1575. Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics
  1576. Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects
  1577. Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population
  1578. Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis
  1579. Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population
  1580. Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1
  1581. Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population
  1582. Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
  1583. Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran
  1584. Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population
  1585. Genotype Polymorphisms of NAT2 and CYP2E1 Genes Associated with Drug Induced Liver Injury (DILI) in Indonesian Tuberculosis Patients
  1586. Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes
  1587. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
  1588. Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells
  1589. Glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
  1590. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …
  1591. Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
  1592. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity
  1593. Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein
  1594. GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.
  1595. GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
  1596. GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer
  1597. Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
  1598. HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells
  1599. Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years
  1600. Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice
  1601. Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
  1602. Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1
  1603. Hepatoprotective Effect of Punica granatum Seed Oil Extract on Paracetamol Intoxication in Rat Via Inhibory Effect of CYP2E1
  1604. Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice
  1605. Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
  1606. High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype
  1607. High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines
  1608. High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats
  1609. High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks
  1610. Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS
  1611. Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1
  1612. Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells
  1613. Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
  1614. Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes
  1615. How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants
  1616. Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites
  1617. Human CYP2E1 is regulated by miR-378
  1618. Human CYP2E1 mediates the formation of glycidamide from acrylamide
  1619. Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results
  1620. Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …
  1621. Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment
  1622. Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells
  1623. Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.
  1624. Human hepatic CYP2E1 expression during development
  1625. Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition
  1626. Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes
  1627. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
  1628. Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors
  1629. Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)
  1630. Identification and functional analysis of a novel human CYP2E1 far upstream enhancer
  1631. Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping
  1632. Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
  1633. Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)
  1634. Identification of CYP2E1 in marmoset monkey
  1635. Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity
  1636. Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
  1637. Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
  1638. Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.
  1639. Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—
  1640. Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity
  1641. Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1-null …
  1642. Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast
  1643. IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …
  1644. IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
  1645. Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues
  1646. Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …
  1647. Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody
  1648. Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
  1649. Impact of CYP2E1 genotype in renal cell and urothelial cancer patients
  1650. Impact of CYP2E1 polymorphisms on the risk of esophageal cancer
  1651. Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia
  1652. Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
  1653. Implication of xenobiotic metabolizing enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma
  1654. in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1
  1655. in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …
  1656. In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …
  1657. In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent
  1658. In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
  1659. In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment
  1660. In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
  1661. In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene
  1662. Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes
  1663. Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
  1664. Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
  1665. Increase expression of CYP2E1 mRNA after methamphetamine administration in rats
  1666. Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
  1667. Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population
  1668. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
  1669. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1
  1670. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
  1671. Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys
  1672. Individual variability of CYP2E1 xenobiotic oxidation in human liver
  1673. Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
  1674. Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.
  1675. Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem
  1676. Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell
  1677. Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress
  1678. Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies
  1679. Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium
  1680. Induction of CYP2E1 activity in Ctenopharyngodon idellus hepatocyte
  1681. Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation
  1682. Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …
  1683. Induction of CYP2E1 in non-alcoholic fatty liver diseases
  1684. Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders
  1685. Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
  1686. Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation
  1687. Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
  1688. Induction of rat hepatic CYP2E1 expression by arecoline in vivo
  1689. Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway
  1690. Influence of Acarbose, Metformin and Pioglitazone on TNF-αand CYP2E1 in Liver Tissue of NAFLD Rat
  1691. Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro
  1692. INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …
  1693. Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …
  1694. Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
  1695. Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
  1696. Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans
  1697. Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
  1698. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …
  1699. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
  1700. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single-dose watercress ingestion; comparison with one week isoniazid treatment
  1701. Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
  1702. Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity
  1703. Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
  1704. Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy
  1705. Inhibition of CYP2E1 by chlormethiazole as measured by chlorzoxazone pharmacokinetics in patients with alcoholism and in healthy volunteers
  1706. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine
  1707. Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells
  1708. Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
  1709. Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice
  1710. Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
  1711. Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model
  1712. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
  1713. Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
  1714. Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract
  1715. Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …
  1716. Inhibition of Urethane-Induced Carcinogenicity in CYP2E1−/− in Comparison to CYP2E1+/+ Mice
  1717. Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice
  1718. Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
  1719. Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots
  1720. Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity
  1721. Insertion polymorphism of CYP2E1 and urinary N -methylformamide after N,N - dimethylformamide exposure in Japanese workers
  1722. Insertion Polymorphism of the CYP2E1 Gene in Patients with Infiltrative Pulmonary Tuberculosis from Bashkortostan
  1723. Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic
  1724. Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …
  1725. Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …
  1726. Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
  1727. Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
  1728. Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)
  1729. Interaction between Polymorphisms in CYP2E1 Rsa Ⅰ Genotypes and Lifestyle with Risk of Stomach Cancer
  1730. Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer
  1731. Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism
  1732. Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality
  1733. Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
  1734. Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
  1735. Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness
  1736. Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells
  1737. Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
  1738. Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1
  1739. Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice
  1740. In-Vitro CYP3A4, CYP2E1 and UGT Activity in Human Liver Microsomes by Strobilanthes crispus Leaf Extracts
  1741. Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes
  1742. Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
  1743. Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice
  1744. Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
  1745. Iron and CYP2E1-dependent oxidative stress and toxicity
  1746. Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver
  1747. Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes
  1748. Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1
  1749. Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
  1750. Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
  1751. Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
  1752. Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women
  1753. Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …
  1754. Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics
  1755. Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy
  1756. Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats
  1757. Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ
  1758. Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole
  1759. Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury
  1760. Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet
  1761. Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats
  1762. Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity
  1763. Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK
  1764. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
  1765. Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
  1766. Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.
  1767. Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1
  1768. Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1
  1769. Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects
  1770. M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …
  1771. Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
  1772. Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
  1773. Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …
  1774. Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar
  1775. Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway
  1776. Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …
  1777. MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA
  1778. Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line
  1779. mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …
  1780. Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate
  1781. Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
  1782. Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis
  1783. Meta-analysis on the relationship between CYP2E1 genetic polymorphism and susceptibility to hepatocellular carcinoma in Chinese
  1784. Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia
  1785. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
  1786. Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …
  1787. Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
  1788. Metabolic activities of cytochrome P-450 CYP2E1 and cytochrome P-450 CYP3A in hepatic alcohol-injuried rats [J]
  1789. Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
  1790. Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice
  1791. Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression
  1792. Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
  1793. Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A
  1794. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity
  1795. Method for in vivo and in vitro Evaluation of CYP2E1 Activities
  1796. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction
  1797. MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
  1798. MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression
  1799. Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.
  1800. Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
  1801. Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver
  1802. Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene
  1803. Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …
  1804. Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
  1805. Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring
  1806. Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver
  1807. Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …
  1808. Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …
  1809. Molecular cloning and sequence analysis of hamster CYP2E1
  1810. Molecular dynamics simulations of CYP2E1
  1811. Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
  1812. Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …
  1813. Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …
  1814. Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen
  1815. mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …
  1816. Multifold Activation of CYP3A4 Caused by Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes
  1817. Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent
  1818. NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …
  1819. NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species
  1820. Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver
  1821. NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis
  1822. NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption
  1823. NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways
  1824. N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
  1825. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes
  1826. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity
  1827. No association between polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the risk of gastric adenocarcinoma in the European prospective investigation into …
  1828. No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population
  1829. No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia
  1830. No significant expression of CYP2E1 in rat liver stellate cells
  1831. Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2
  1832. Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes
  1833. Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons
  1834. Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk
  1835. Novel CYP2E1 haplotype identified in a South African cohort
  1836. NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review
  1837. Nrf2 and antioxidant defense against CYP2E1 toxicity
  1838. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
  1839. Obesity‐induced CYP2E1 activity in children
  1840. Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
  1841. of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1
  1842. of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 …
  1843. of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …
  1844. OF THE PLANT PHENOLIC QUERCETIN ON PROTEIN AND mRNA EXPRESSIONS OF XENOBIOTIC METABOLIZING CYP1A1, CYP2E1, NQO1 AND GST …
  1845. of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1
  1846. Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
  1847. Ontogeny of rat CYP2E1 and CYP1A2: a characterization and a pharmacokinetic model
  1848. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells
  1849. Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)
  1850. Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism
  1851. overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1
  1852. Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity
  1853. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
  1854. Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
  1855. Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …
  1856. Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis
  1857. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
  1858. Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes
  1859. Oxidative stress, toxicology, and pharmacology of CYP2E1
  1860. p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.
  1861. Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression
  1862. patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1
  1863. Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression
  1864. Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization
  1865. Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation
  1866. Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1.
  1867. Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation
  1868. Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?
  1869. Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
  1870. Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
  1871. Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism
  1872. Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase
  1873. Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
  1874. PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes
  1875. Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
  1876. Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway
  1877. Polimorfismos en los genes de la enzima alcohol deshidrogenasa (ADH1) y la citocromo P450 2E1 (CYP2E1) en pacientes con cirrosis y carcinoma …
  1878. Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida
  1879. Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway
  1880. Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users
  1881. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …
  1882. Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).
  1883. Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma
  1884. Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism
  1885. Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity
  1886. Polymorphisms in detoxification genes CYP1A1, CYP2E1, GSTT1 and GSTM1 in gastric cancer susceptibility
  1887. Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …
  1888. Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are Associated with Susceptibility and Chemotherapy Response in Non-small-cell Lung Cancer …
  1889. Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain
  1890. Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)
  1891. Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients
  1892. Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world
  1893. Polymorphisms of Alcohol Metabolizing Enzymes in Indigenous Mexican Population: Unusual High Frequency of CYP2E1*c2 Allele
  1894. Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians
  1895. Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group
  1896. Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population
  1897. Polymorphisms of GSTP1 and GSTT1 , but not of CYP2A6 , CYP2E1 or GSTM1 , modify the …
  1898. Polymorphisms of NAT2, CYP2E1, GST, and HLA Related to Drug‑Induced Liver Injury in Indonesian Tuberculosis Patients
  1899. Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk
  1900. Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study
  1901. Polymorphisms of the Cytochrome P450 (CYP1A1, CYP2E1) and Microsomal Epoxide Hydrolase (mEPHX) Genes in Cystic Fibrosis and Chronic Respiratory …
  1902. Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
  1903. Possible impact of human CYP2E1 polymorphisms on the metabolism of acrylonitrile
  1904. Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability
  1905. Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme
  1906. Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
  1907. Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća
  1908. Prediction of The Needs for Benzene Detox with Foods Intake Containing CYP2E1 Enzyme, Sulfation, and Glutathione at Gas Stations Pancoranmas Depok …
  1909. Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice
  1910. Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
  1911. Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes
  1912. Progress of research on characteristics of cytochrome P-450 CYP2E1 in protein structure and regulation mechanisms
  1913. Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
  1914. Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells
  1915. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice
  1916. Protective Effect of Curcumin on Acrylamide-Induced Hepatic and Renal Impairment in Rats: Involvement of CYP2E1
  1917. Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α
  1918. Protective Effects of CYP2E1 Inhibitors on Metabolic Syndrome-induced Liver Injury in Guinea Pigs
  1919. Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB
  1920. Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells
  1921. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats
  1922. Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
  1923. Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells
  1924. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells
  1925. Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems
  1926. psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
  1927. Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice
  1928. Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1
  1929. Pulmonary CYP2E1 bioactivates 1, 1-dichloroethylene in male and female mice.
  1930. Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats
  1931. Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency
  1932. Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment
  1933. Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat …
  1934. Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1
  1935. Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO
  1936. Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …
  1937. Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
  1938. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
  1939. Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels
  1940. Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk
  1941. Red meat intake, CYP2E1 genetic polymorphisms, and colorectal cancer risk
  1942. Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss
  1943. Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
  1944. Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
  1945. Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
  1946. Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
  1947. Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats
  1948. Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia
  1949. Relationship among Qi-deficiency constitution and CYP2E1 gene polymorphisms and anti-tuberculosis drug-induced hepatitis
  1950. Relationship between alcoholism and CYP2E1 C/D polymorphism
  1951. Relationship between alcoholism and CYP2E1 genotypes
  1952. Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis
  1953. Relationship between CYP2E1, GSTT1 genetic polymorphisms and susceptibility to gastric cancer
  1954. Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is …
  1955. Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene
  1956. Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism
  1957. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …
  1958. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …
  1959. Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang
  1960. Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China
  1961. Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
  1962. Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis
  1963. Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST
  1964. Relationship of CYP2E1 RsaⅠ genetic polymorphism and smoking, alcohol drinking habit with risk of rectal cancer
  1965. Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …
  1966. RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES
  1967. Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice
  1968. Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone
  1969. Relevance of CYP2E1 to non-alcoholic fatty liver disease
  1970. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1
  1971. Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
  1972. Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …
  1973. Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer
  1974. Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1
  1975. Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people
  1976. Research on the relationship between polymorphism of CYP2E1 and dermatitis medicamentosa-like of trichloroethylene [J]
  1977. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
  1978. Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
  1979. Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats
  1980. Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers
  1981. Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice
  1982. Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
  1983. Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme
  1984. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability
  1985. Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development
  1986. Role of brain acetaldehyde in drinking preference: genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …
  1987. Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells
  1988. Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction
  1989. Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
  1990. Role of CYP2E1 (PstI/RsaI) gene polymorphisms on the tacrolimus drug toxicity of kidney transplantations among South Indians
  1991. Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response
  1992. Role of CYP2E1 and NQO1 polymorphisms in oxidative stress derived cancer in Thais with and without dyslipidemia
  1993. Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital
  1994. Role of CYP2E1 gene polymorphisms association with hepatitis risk in Northeast India
  1995. Role of CYP2E1 Immunoglobulin G4
  1996. Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis
  1997. Role of CYP2E1 in deramciclane metabolism
  1998. Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo
  1999. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity
  2000. Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption
  2001. Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells
  2002. Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances
  2003. Role of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases
  2004. Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and Formation of DNA and Hemoglobin Adducts
  2005. Role of CYP2E1 in the hepatotoxicity of acetaminophen
  2006. Role of CYP2E1 in the mouse model of MPTP toxicity
  2007. Role of CYP2E1 in the pathogenesis of alcoholic liver disease
  2008. Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway
  2009. Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
  2010. Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis
  2011. Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse
  2012. Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice
  2013. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
  2014. Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1
  2015. Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1
  2016. Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice
  2017. Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
  2018. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
  2019. Role of P38 MAP kinase in CYP2E1 dependent arachidonic acid toxicity
  2020. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity
  2021. Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity
  2022. Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells
  2023. Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …
  2024. Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene
  2025. Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene
  2026. Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells
  2027. Roles of CYP1A1 and CYP2E1 Gene Polymorphisms in Oral Submucous Fibrosis
  2028. Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice
  2029. Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane
  2030. Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene
  2031. RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure
  2032. RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study
  2033. Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity
  2034. S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …
  2035. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury
  2036. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice
  2037. Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
  2038. Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation
  2039. Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …
  2040. Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat
  2041. Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole
  2042. Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of liver graft hepatitis C recurrence
  2043. Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C
  2044. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1
  2045. Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver
  2046. Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities
  2047. Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice
  2048. Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
  2049. Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations
  2050. Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug
  2051. Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
  2052. Similarity Check: Genotype Polymorphisms Of Nat2 And CYP2E1 Genes Associated With Drug Induced Liver Injury (Dili) In Indonesian Tuberculosis Patients
  2053. Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses
  2054. Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570
  2055. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes
  2056. Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation
  2057. Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity
  2058. St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
  2059. Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing
  2060. Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice
  2061. Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes
  2062. Structure-functional characterization of cytochrome P4502E1 (CYP2E1)
  2063. Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells
  2064. Studies on Pharmacokinetic Interaction Among CYP1A2, CYP2E1 and CYP3A4 Probes in Rats [J]
  2065. Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran
  2066. Study of genetic polymorphisms of CYP2E1 and GSTM1
  2067. Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
  2068. Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …
  2069. STUDY ON AA METABOLISM IN RAT LIVER AND THE EXPRESSION OF CYP2E1
  2070. Study on Chinese medicine constitution and its relation with CYP2E1 gene polymorphisms of anti‐tuberculosis drug‐induced hepatitis
  2071. Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver
  2072. Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease
  2073. Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer
  2074. Study the effect of Baijie Capsule on cytochrome P450 isozymes CYP2C19, CYP2E1 by cocktail probe drugs
  2075. Study the effect of cytochrome p450 isozymes cyp1A2, cyp3A4, CYP2E1 following administration of Zhenqi Fuzheng Capsules by cocktail probe drugs [J]
  2076. Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates
  2077. Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis
  2078. Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele
  2079. Sus scrofa mRNA for cytochrome p450 2E1 (CYP2E1 gene)
  2080. Sus scrofa partial CYP2E1 gene for cytochrome p450 2E1, exon 9 and partial CDS
  2081. Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …
  2082. Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese
  2083. Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury
  2084. Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1
  2085. Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury
  2086. Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer
  2087. Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices
  2088. Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
  2089. Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene
  2090. The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
  2091. The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia
  2092. The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
  2093. The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression
  2094. The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis
  2095. The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients
  2096. The Changes in the Analgesic Effect of Probe Drug Chlorzoxazone Metabolized by CYP2E1 on Alcoholic Liver Injury in Rats
  2097. The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism
  2098. The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity
  2099. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine
  2100. The difference of metabolism activity of CYP2E1 between in immune liver damage rats and in alcohol-mediated hepatic injury rats
  2101. The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice
  2102. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
  2103. The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat
  2104. The effect of ethanol and nitric oxide on the N-nitrosodimethylamine formation in HepG2 cells overexpressing CYP2E1
  2105. THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.
  2106. The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
  2107. The Effect of Huangqi on CYP2E1 Activity of Diabetic Rats
  2108. The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.
  2109. The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney
  2110. The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
  2111. The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children
  2112. The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects
  2113. The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint
  2114. The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
  2115. The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities
  2116. The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine
  2117. The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis
  2118. The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1.
  2119. The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …
  2120. THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION
  2121. The effects of toluene on the total CYP450 content and on levels of CYP2E1 and 2B6 Isoforms in the rat liver
  2122. The essential role of CYP2E1 in metabolism and hepatotoxicity of N,N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study
  2123. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
  2124. The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
  2125. The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
  2126. The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis
  2127. The genotype of CYP2E1 and liver-derived serum enzymes
  2128. The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
  2129. The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population
  2130. The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response
  2131. The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures
  2132. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model
  2133. The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver
  2134. The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
  2135. The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation
  2136. The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
  2137. The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis
  2138. The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury
  2139. The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro
  2140. The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway
  2141. The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1
  2142. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
  2143. The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates
  2144. The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide
  2145. The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver
  2146. The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase
  2147. The Physiological Mechanism of Improved Formaldehyde Resistance in Petunia hybrida Harboring a Mammalian CYP2E1 Gene
  2148. The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde
  2149. The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
  2150. The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies
  2151. The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans
  2152. The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them
  2153. The regulation of CYP2E1 gene expression and its role in breast cancer
  2154. The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer
  2155. The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
  2156. The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.
  2157. The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives
  2158. The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis
  2159. The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization
  2160. The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system
  2161. The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
  2162. The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity
  2163. THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA
  2164. The role of inflammatory and oxidative stress, CYP2E1 and bile acid disturbance in rat liver injury induced by isoniazid and lipopolysaccharide co-treatment
  2165. The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
  2166. The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …
  2167. The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes
  2168. Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1
  2169. Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model
  2170. Therapeutic potential of CYP2E1 inhibitor combined N-acetyl-cysteine in acute acrylonitrile intoxication in rats
  2171. Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system
  2172. Tissue-specific expression and methylation of the human CYP2E1 gene
  2173. Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2
  2174. Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
  2175. Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity
  2176. Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene
  2177. Transcriptional control of CYP2E1 in the perivenous liver region and during starvation
  2178. Transcriptional control of the rat hepatic CYP2E1 gene.
  2179. Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity
  2180. Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …
  2181. Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene
  2182. Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
  2183. Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
  2184. Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane
  2185. Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
  2186. Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
  2187. TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity
  2188. TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.
  2189. TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression
  2190. Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …
  2191. Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver
  2192. Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: A comparative study with 1000 genomes population
  2193. UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3
  2194. Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice
  2195. Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes
  2196. Urinary Biomarker of Prenatal Exposure to Disinfection Byproducts, Maternal Genetic Polymorphisms in CYP2E1 and GSTZ1, and Birth Outcomes
  2197. Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity
  2198. Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol
  2199. Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …
  2200. Use of molecular simulation for mapping conformational CYP2E1 epitopes
  2201. Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene
  2202. Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
  2203. Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1
  2204. Value of polymorphisms and DNA methylation for the expression of CYP2E1 enzyme: implications in pharmacogenomics
  2205. Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma
  2206. Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?
  2207. Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds
  2208. Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats
  2209. Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition
  2210. XRCC1 and CYP2E1 polymorphisms as susceptibility factors of plasma mutant p53 protein and anti-p53 antibody expression in vinyl chloride monomer-exposed …
  2211. XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …
  2212. Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like
  2213. ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study
  2214. π–π Stacking mediated drug–drug interactions in human CYP2E1
  2215. Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
  2216. Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress
  2217. Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
  2218. … patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1
  2219. In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent
  2220. Cytochrome P450 2E1 (CYP2E1) positively regulates lipid catabolism and induces browning in 3T3-L1 white adipocytes
  2221. Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole
  2222. Expression and activities of hepatic cytochrome P450 (CYP1A, CYP2A and CYP2E1) in entire and castrated male pigs
  2223. Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO
  2224. CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
  2225. Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats
  2226. … in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1
  2227. Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis
  2228. Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes
  2229. Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are associated with susceptibility and chemotherapy response in non-small-cell lung cancer patients
  2230. Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis
  2231. TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity
  2232. Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene
  2233. The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation
  2234. Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population
  2235. Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer
  2236. Cytochrome P450 CYP2E1 suppression ameliorates cerebral ischemia reperfusion injury
  2237. Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review …
  2238. Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity
  2239. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes
  2240. CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir
  2241. Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme
  2242. Chronic acrylamide exposure in male mice results in elevated DNA damage in the germline and heritable induction of CYP2E1 in the testes
  2243. Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities
  2244. Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells
  2245. The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them
  2246. Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women
  2247. Urinary biomarker of prenatal exposure to disinfection byproducts, maternal genetic polymorphisms in CYP2E1 and GSTZ1, and birth outcomes
  2248. CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene
  2249. Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4
  2250. Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …
  2251. Cooperative effects for CYP2E1 differ between styrene and its metabolites
  2252. Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk
  2253. Effectiveness of antioxidant treatments on cytochrome P450 2E1 (CYP2E1) activity after alcohol exposure in humans and in vitro models: A systematic review
  2254. Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR
  2255. Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis
  2256. Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice
  2257. Genetic polymorphisms of drug‐metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population
  2258. HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells
  2259. Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China
  2260. Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—impact of the extent of ortho-chlorination
  2261. Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patients
  2262. CHIP−/−-mouse liver: adiponectin-AMPK-FOXO-activation overrides CYP2E1-elicited JNK1-activation, delaying onset of NASH: therapeutic implications
  2263. Protective effect of curcumin on acrylamide-induced hepatic and renal impairment in rats: Involvement of CYP2E1
  2264. Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis
  2265. Altered vulnerability to asthma at various levels of ambient Benzo [a] Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms
  2266. CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis
  2267. Genetic polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and susceptibility to anti-tuberculosis drug-induced hepatotoxicity: a Chinese population-based …
  2268. CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
  2269. Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1
  2270. Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats
  2271. Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines
  2272. Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
  2273. Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity
  2274. … bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …
  2275. Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes
  2276. Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats
  2277. Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver
  2278. The essential role of CYP2E1 in metabolism and hepatotoxicity of N, N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study
  2279. Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1
  2280. Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses
  2281. Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population
  2282. Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results
  2283. CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
  2284. Aidi injection altered the activity of CYP2D4, CYP1A2, CYP2C19, CYP3A2, CYP2E1 and CYP2C11 in normal and diethylnitrosamine-induced hepatocellular …
  2285. Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1
  2286. Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury
  2287. Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots
  2288. Concentration-dependent inhibitory effect of baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …
  2289. The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia
  2290. Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese
  2291. Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations
  2292. CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling
  2293. Genetic interaction between NAT2, GSTM1, GSTT1, CYP2E1, and environmental factors is associated with adverse reactions to anti-tuberculosis drugs
  2294. Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population
  2295. Organosulfur compounds in fermented garlic extracts and the effects on alcohol induced cytotoxicity in CYP2E1-transfected HepG2 cells
  2296. TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy‐proven nonalcoholic fatty …
  2297. Metallothionein protects against isoniazid-induced liver injury through the inhibition of CYP2E1-dependent oxidative and nitrosative impairment in mice
  2298. The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver
  2299. A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations
  2300. Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …
  2301. Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
  2302. Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy
  2303. CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies
  2304. CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy
  2305. Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1
  2306. Protective effect of Schisandra chinensis total lignans on acute alcoholic-induced liver injury related to inhibiting CYP2E1 activation and activating the Nrf2/ARE …
  2307. Effect of Acrylamide Treatment on CYP2E1 Expression and Redox Status in Rat Hepatocytes
  2308. Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma
  2309. … Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …
  2310. Association of CYP2E1, STK15 and XRCC1 polymorphisms with risk of breast cancer in Malaysian women
  2311. Alcohol suppresses cardiovascular diurnal variations in male normotensive rats: Role of reduced PER2 expression and CYP2E1 hyperactivity in the heart
  2312. Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss
  2313. CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator
  2314. Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures
  2315. Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …
  2316. CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
  2317. The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response
  2318. Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1
  2319. The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide
  2320. Adverse outcome pathway on CYP2E1 activation leading to liver cancer
  2321. Increased DNA damage is not associated to polymorphisms in OGGI DNA repair gene, CYP2E1 detoxification gene, and biochemical and hematological findings in …
  2322. CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity
  2323. Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean
  2324. Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes
  2325. Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver
  2326. Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress
  2327. A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma
  2328. Insulin resistance enhances binge ethanol-induced liver injury through promoting oxidative stress and up-regulation CYP2E1
  2329. Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies
  2330. CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease
  2331. Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …
  2332. CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India
  2333. Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice
  2334. Effect of CYP2E1 gene polymorphisms on lamb odor and flavor in Indonesian sheep
  2335. Coordinate regulation of CYP2E1 by β-catenin-and hepatocyte nuclear factor 1α-dependent signaling
  2336. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription
  2337. Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …
  2338. Intracellular ethanol‐mediated oxidation and apoptosis in HepG2/CYP2E1 cells impaired by two active peptides from seahorse (Hippocampus kuda bleeler) protein …
  2339. The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
  2340. CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls
  2341. A novel role of CYP2E1 in human megakaryocyte development
  2342. Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity
  2343. Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia
  2344. The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway
  2345. Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways
  2346. … ‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …
  2347. Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis
  2348. High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype
  2349. … of interactions of cathinone with human recombinant cytochrome P450 CYP (1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
  2350. Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes
  2351. Relationships among N, N-dimethylformamide exposure, CYP2E1 and TM6SF2 genes, and non-alcoholic fatty liver disease
  2352. Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
  2353. CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity
  2354. Romidepsin (FK228) in a mouse model of lipopolysaccharide-induced acute kidney injury is associated with down-regulation of the CYP2E1 gene
  2355. Effects of insulin treatment on hepatic CYP1A1 and CYP2E1 activities and lipid peroxidation levels in streptozotocin-induced diabetic rats
  2356. The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism
  2357. CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau
  2358. Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
  2359. … of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5
  2360. Genetic polymorphism of the drug-metabolizing enzyme Cytochrome P4502E1 (CYP2E1) in a healthy Saudi population
  2361. Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis
  2362. Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury
  2363. Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population
  2364. Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice
  2365. CYP2E1, oxidative stress, post-translational modifications and lipid metabolism
  2366. CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer
  2367. … stem cells rescue rat hippocampal cells from aluminum oxide nanoparticle-induced apoptosis via regulation of P53, Aβ, SOX2, OCT4, and CYP2E1
  2368. High-Risk HPV with Multiple Infections Promotes CYP2E1, Lipoperoxidation and Pro-Inflammatory Cytokines in Semen of Asymptomatic Infertile Men
  2369. Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen
  2370. Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia
  2371. Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes
  2372. Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice
  2373. Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1
  2374. DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil
  2375. CYP2E1 RsaI/PstI polymorphism and liver cancer risk among east Asians: a HuGE review and meta-analysis
  2376. Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model
  2377. Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …
  2378. Functional PstI/RsaI polymorphisms in the CYP2E1 gene among south Indian populations
  2379. Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism
  2380. … quantification of metabolic reaction products catalysed by CYP2E1 enzyme activity: inhibitory effect of cytochrome P450 enzyme CYP2E1 by salicylic acid in rat liver …
  2381. Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis …
  2382. Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-CYP2E1 Signaling
  2383. RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure
  2384. The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans
  2385. Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1
  2386. Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α
  2387. Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
  2388. RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study
  2389. Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality
  2390. Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats
  2391. Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran
  2392. Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells
  2393. The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells
  2394. CYP2E1 testis expression and alcohol-mediated changes of rat spermatogenesis indices and type I collagen
  2395. π–π Stacking mediated drug–drug interactions in human CYP2E1
  2396. Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …
  2397. Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes
  2398. Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population
  2399. Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes
  2400. Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
  2401. CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients
  2402. Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats
  2403. Increased oxidative stress and toxicity in ADH and CYP2E1 overexpressing human hepatoma VL-17A cells exposed to high glucose
  2404. Targeted delivery of CYP2E1 recombinant adenovirus to malignant melanoma by bone marrow-derived mesenchymal stem cells as vehicles
  2405. Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet
  2406. Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A …
  2407. Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity
  2408. Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro
  2409. CYP2E1 genetic polymorphism with dietary, tobacco, alcohol habits, H. pylori infection status and susceptibility to stomach cancer in Mizoram, India
  2410. Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1
  2411. CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population
  2412. Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan
  2413. Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression
  2414. … experimental and theoretical study of ROS scavenging by organosulfur compounds from garlic: In silico analysis of metabolic pathways and interactions on CYP2E1
  2415. Cytochrome P450 genes (CYP2E1 and CYP1A1) variants and susceptibility to chronic hepatitis B virus infection
  2416. Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies
  2417. … -2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
  2418. Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis
  2419. Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury
  2420. Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs
  2421. Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway
  2422. Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population
  2423. CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls
  2424. Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats
  2425. CYP2C8 and CYP2E1 genetic variants increase risk of tuberculosis in northwest Chinese Han population
  2426. Polymorphisms in the CYP2E1 and GSTM1 Genes as Possible Protection Factors for Leprosy Patients
  2427. Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent
  2428. Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping
  2429. A Systematically Combined Genotype and Functional Combination Analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in Different Geographic Areas of …
  2430. Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis
  2431. Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …
  2432. Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …
  2433. Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …
  2434. Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …
  2435. Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome
  2436. Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han populations in the Inner Mongolian region
  2437. Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
  2438. In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …
  2439. N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
  2440. Investigation of CYP2E1 and Caspase-3 Gene Expressions in COVID-19 patients
  2441. How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants
  2442. Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …
  2443. CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer
  2444. Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …
  2445. Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels
  2446. 4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism
  2447. In-Vitro CYP3A4, CYP2E1 and UGT activity in human liver microsomes by Strobilanthes crispus leaf extracts
  2448. Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk
  2449. The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis
  2450. Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population
  2451. Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
  2452. Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1
  2453. Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity
  2454. CYP2E1 inhibition and NF_κB Signaling Pathway are Involved in the Protective Molecular Effect of Origanum floribundum against Acetaminophen-induced …
  2455. The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies
  2456. Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population
  2457. Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α
  2458. Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells
  2459. 1, 3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice
  2460. CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China
  2461. Chemical characteristics for optimizing CYP2E1 inhibition
  2462. Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1
  2463. Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N, N-dimethylformamide occupational exposure-induced liver injury
  2464. A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
  2465. Novel CYP2E1 haplotype identified in a South African cohort
  2466. Adrenergic blocker terazosin potentially suppresses acetaminophen induced-acute liver injury in animal models via CYP2E1 gene
  2467. Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment
  2468. Vitamin E in vivo studies on the activity of antioxidant enzymes and CYP2E1 expression in high PUFA-treated brains
  2469. Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
  2470. A study on the optimization of CYP2E1 enzyme activity in C57Bl/6 mouse brain and liver
  2471. Chemoprotective Effect of Daphnetin Against Benzene-induced Leukemia via Alteration of CYP2E1
  2472. Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers
  2473. Ethanol-induced oxidative stress modifies inflammation and angiogenesis biomarkers in retinal pigment epithelial cells (ARPE-19): role of CYP2E1 and its inhibition …
  2474. The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
  2475. … effect of seed coat ofEuryale ferox extract in non-alcoholic fatty liver disease induced by high-fat diet in mice by increasing IRs-1 and inhibiting CYP2E1
  2476. Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1
  2477. Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices
  2478. Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1
  2479. Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease
  2480. Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro
  2481. No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population
  2482. Roles of CYP1A1 and CYP2E1 gene polymorphisms in Oral submucous fibrosis
  2483. Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations
  2484. Camelus dromedarius putative cytochrome P450 enzyme CYP2E1: complete coding sequence and phylogenetic tree
  2485. Alteration of CYP2E1, DBN1, DNMT1, miRNA-335, miRNA-21, c-Fos and Cox-2 gene expression in prefrontal cortex of rats’ offspring submitted to prenatal ethanol …
  2486. Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes
  2487. Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms and lung cancer risk in Chinese population
  2488. Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene
  2489. Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis
  2490. Effect of BI-1 on insulin resistance through regulation of CYP2E1
  2491. Propolis alleviates 4‐aminobiphenyl‐induced oxidative DNA damage by inhibition of CYP2E1 expression in human liver cells
  2492. Protective effects of garlic oil against 1, 3-dichloro-2-propanol-induced hepatotoxicity: Role of CYP2E1 and MAPKs
  2493. Pyridoxine deficiency modulates benzene inhalation-induced hematotoxicity associated with hepatic CYP2E1 activity in B6C3F1 mice
  2494. Polymorphisms in alcohol dehydrogenase (ADH1) and cytochrome p450 2E1 (CYP2E1) genes in patients with cirrhosis and/or hepatocellular carcinoma
  2495. CYP2E1: the anesthesia enzyme
  2496. Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis
  2497. Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?
  2498. CYP2E1 RsaI/PstI polymorphisms contributed to oral cancer susceptibility: a meta-analysis
  2499. Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk
  2500. Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …
  2501. Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue
  2502. CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck Cancer in the Turkish population
  2503. Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms
  2504. Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver
  2505. Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells
  2506. Association between CYP2E1 genetic polymorphisms and urinary cancer risk: a meta-analysis
  2507. mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …
  2508. Investigation of cytochrome p450 CYP1A2, CYP2D6, CYP2E1 and CYP3A4 gene expres-sions and polymorphisms in alcohol with-drawal
  2509. 2‐mercaptobenzothiazole generates γ‐H2AX via CYP2E1‐dependent production of reactive oxygen species in urothelial cells
  2510. CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease
  2511. Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran
  2512. Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity
  2513. Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment
  2514. Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line
  2515. Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites
  2516. Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells
  2517. Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
  2518. Induction of rat hepatic CYP2E1 expression by arecoline in vivo
  2519. Ethanol-induced CYP2E1 Expression is Reduced by Lauric Acid via PI3K Pathway in HepG2 Cells
  2520. The physiological mechanism of improved formaldehyde resistance in Petunia hybrida harboring a mammalian CYP2E1 gene
  2521. Obesity‐induced CYP2E1 activity in children
  2522. CYP2E1, GSTM1, and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai …
  2523. Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …
  2524. Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats
  2525. All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …
  2526. CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
  2527. End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes
  2528. ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study
  2529. CYP2E1 activity and children with obesity: possible confounding factors
  2530. Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …
  2531. Exogenous toluene gas removal improvement in recombinant rabbit cytochrome P450 2E1 (CYP2E1)-transgenic Ardisia pusilla DC
  2532. CYP2E1 polymorphisms and colorectal cancer
  2533. Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury. Antioxidants 2021, 10, 52
  2534. Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
  2535. Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats
  2536. Association of CYP1A1 and CYP2E1 gene polymorphisms with prostate cancer in a Lebanese population
  2537. Anti-tuberculosis drug-induced liver injury correlated with the methylation in the promoter regions of CYP2E1 and GSTM1
  2538. Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: a comparative study with 1000 genomes population
  2539. The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities
  2540. The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice
  2541. Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid
  2542. Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
  2543. Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring
  2544. M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …
  2545. Effect of Dietary Supplementation with Dried Tuber of Jerusalem Artichoke on Skatole Level in Backfat and CYP2E1 mRNA Expression in Liver of Boars
  2546. Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane
  2547. An improved in vitro method for screening toxin and medicine targeting CYP2E1
  2548. … : Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and …
  2549. The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients
  2550. Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
  2551. Effect of Er Chen Tang on CYP2E1 and mitochondrial energy metabolism in nonalcoholic fatty liver disease
  2552. Requirement prediction for toluene detox with foods intake rich in CYP2E1 enzyme and glycine to prevent nerve and kidney damage at shoe home industry …
  2553. Association of CYP1A1 and CYP2E1 gene polymorphism with risk of arsenism caused by coal-burning
  2554. Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …
  2555. Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group
  2556. Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug
  2557. Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province
  2558. Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population
  2559. Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity
  2560. Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women
  2561. TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.
  2562. Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
  2563. Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like
  2564. Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer
  2565. THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA
  2566. CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia
  2567. Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1
  2568. Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …
  2569. Chemoprotective Effect of Daphnetin against Benzene Induced Leukemia Cancer via Alteration of CYP2E1
  2570. Modulatory effects of persimmon vinegar and its fractions on hepatic immune response and CYP2E1 activation in chronically alcohol drinking rats (649.4)
  2571. Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I
  2572. Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity
  2573. CYP2E1 Associated Dysregulation of Nucleotide Excision Repair (NER) Process In Hepatocellular Carcinoma
  2574. Heliotropium undulatum attenuates hydrazine induced hepatotoxicity: involvement of cytochrome P450 CYP2E1 and oxidative stress
  2575. Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …
  2576. In Silico Approach for Hepatoprotective Activity of Piper crocatum Leaf Towards CYP2E1 Protein:(TJPS-2020-0154. R2)
  2577. Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …
  2578. Extracts of Poria cocos polysaccharides improves alcoholic liver disease in mice via CYP2E1 and NF-κB inflammatory pathways
  2579. Liver Tissue-specific Genes IGFALS, CYP3A4, SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer
  2580. CYP2E1-DEPENDENT VARIATIONS IN HEPATOCYTES DAMAGE DURING TREATMENT OF TUBERCULOSIS
  2581. Higher CYP2E1 activity is a risk factor for hepatocarcinogenesis
  2582. Expression of CYP2E1 in different brain regions during the formation of toxic cerebral edema induced by 1, 2-DCE in mice and its effect on cerebral edema formation
  2583. Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)
  2584. Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism
  2585. The Polymorphism and Expression of CYP2E1 Gene and Its Relation to Carcass and Meat Quality of Indonesian Lamb
  2586. The regulation of CYP2E1 gene expression and its role in breast cancer
  2587. Effect of grapefruit juice on CYP2E1 gene expression in obese and control rats
  2588. CYP2E1 mediated ethanol metabolism in ARPE-19 cells.
  2589. Correction: Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
  2590. Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2
  2591. The correlation between CYP2E1 and CYP1A1 genotypes with the susceptibility of HBV infection in northern Guangzhou people
  2592. COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …
  2593. Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol-Drug Interactions.
  2594. MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression
  2595. Evaluation of smoke burning AnbarNesara on changes of the gene expression of P53 and CYP2E1 in human liver cancer cells
  2596. Profile of retinal pigment epithelium response to ethanol: Role of CYP2E1
  2597. CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism
  2598. Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća
  2599. Relationship between CYP2E1 genetic polymorphism and susceptibility of gastric cancer in Hakkaness
  2600. Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.
  2601. Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
  2602. … Protects Hepato-Renal Tissues Against Antituberculosis Drugs Induced Toxic Manifestations by Modulating IL-6, IGF-1, CYP2E1, Biochemical and Ultra …
  2603. Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
  2604. Results of intensive phase tretament of tuberculosis treatment according to CYP2E1 genotype
  2605. Association of CYP2E1 Gene Polymorphisms with the Risk of Schizophrenia in the Bangladeshi Population
  2606. Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
  2607. Enhanced Hepatotoxicity of Extract of Polygoni Multiflori Radix after Inhibition of CYP2E1 and Screening of Toxic Constituents
  2608. CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults
  2609. Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group. Open Access Maced J Med Sci …
  2610. CYP2E1 activity in cisplatin resistant cancer cells
  2611. Effect of temperature on carp CYP2E1-like isoform activity.
  2612. The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1
  2613. CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.
  2614. The Oxidative Effect Of Nlrp3 And CYP2E1 In Development Of Renal Failure Associated With Hypertension And Diabetes Mellitus Diseases
  2615. UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3
  2616. Distribution of single nucleotide polymorphisms of CYP2E1 gene in Congjiang Xiang-pigs.
  2617. Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds
  2618. Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1
  2619. TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression
  2620. Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran
  2621. Effects of trichloroethylene toxicity on normal human liver cells and hepatocytes with CYP2E1 gene overexpression
  2622. Assessing specificity of indazole derivatives as inhibitors to CYP2E1
  2623. Effects of three kinds of tea beverages on intestinal first-pass effect and liver Cyp3a, CYP2E1 activities in mice
  2624. Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes
  2625. Association of genetic polymorphisms of CYP2E1 and MPO genes with acute leukemia risk: a meta-analysis.
  2626. Effect of Jiangzhiligan Granules on CYP2E1 Gene and Protein Expression of Rat Model with Non-alcoholic Fatty Liver Disease
  2627. Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.
  2628. Effects of Mailuoning injection on rat activities of CYP1A2, CYP2E1 and CYP3A4 using a three-drug Cocktail approach
  2629. Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …
  2630. CYP2E1 Epigenetic Regulation In Workers Exposed To Low-Level Voc Mixture: Relationship With Nitrosative Stress And Inflammation
  2631. The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro
  2632. Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
  2633. The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde
  2634. Non‐Additive Effects of Changing the Composition of the Cytochrome P450 Ensemble in Human Liver Microsomes: the Focus on CYP2E1 and Alcohol‐Drug …
  2635. Higher chlorzoxazone clearance in obese children compared with none-obese peers, an open-label explorative pharmacokinetic study of CYP2E1 activity
  2636. Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation
  2637. CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
  2638. A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells
  2639. Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer
  2640. CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity
  2641. Study on CYP2E1 gene polymorphism and the relationship between methylation level of its promoter region and liver injury induced by anti-tuberculosis drugs in …
  2642. Relative contribution of hepatic CYP3A and CYP2E1 to oxidative stress upon CHIP E3 ligase knockdown
  2643. Effect of Neiyixiao on Hepatic CYP1A2, CYP2E1, CYP3A4 in Rats with Endometriosis
  2644. Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis
  2645. Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.
  2646. CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation
  2647. Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation
  2648. Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?
  2649. CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
  2650. Study the Correlation of GSTM1 and CYP2E1 Gene Polymorphism and Genetic Susceptibility to Non-small Cell Lung Cancer in Shenzhen Area
  2651. CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …
  2652. Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)
  2653. Effects of cefetamet hydrochloride injection on activity of CYP1A2, CYP3A4 and CYP2E1 in liver microsomes of rats
  2654. Evaluation of genotoxicity of environmental contaminants, production of bio-sensor cell lines and measurment of CYP2E1 enzymatic activity
  2655. B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …
  2656. An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies
  2657. Analysis of Protein and mRNA Expressions of CYP1A1 and CYP2E1 Enzymes In Liver, Colon And Prostate Cancer Cell Lines to Study Drug and Carcinogen …
  2658. Correction: Investigation of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations
  2659. Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida
  2660. GENOTYPE POLYMORPHISMS OF NAT2 AND CYP2E1 GENES ASSOCIATED WITH DRUG INDUCED LIVER INJURY (DILI) IN INDONESIAN …
  2661. Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats.
  2662. Modulatory effects of persimmon vinegar and its fractions on alcohol-induced inflammatory stress and CYP2E1 expressions in the liver of Wistar rats
  2663. CYP2E1 rs2031920, COMT rs4680 Polymorphisms, Cigarette Smoking, Alcohol Use and Lung Cancer Risk in a Japanese Population
  2664. The role of brain acetaldehyde in drinking preference: Genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …
  2665. The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children
  2666. Nonclassical ROR Alpha Pathway Switches Transcriptional Mode of ERR Gamma that Results in Repression of Alcohol-induced CYP2E1 Expression
  2667. Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620
  2668. Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and carcinogen …
  2669. Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …
  2670. Hepatoprotective Activity of Eugenol, Hesperidin and Lepidium Sativum Alkaloids in Rats with Liver Injury through Attenuating CYP2E1/Nuclear Factor Kappa-B and …
  2671. S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …
  2672. ISALPDC-03: CYP2E1 Regulation of Ethanol-Induced Intestinal miRNAs in Liver Injury
  2673. Comparison of Polymorphism rs3813865 Cytochrome P450 Family 2 Subfamily E Polypeptide 1 (CYP2E1) Gene in Various Clinical Stage of Undifferentiated …
  2674. 0466 The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint
  2675. Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
  2676. Regulation of il-1 and TNF-α on metabolic enzyme CYP2E1 in immunological liver injury in rats
  2677. … ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …
  2678. Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1
  2679. Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
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